LOCUS       c01133_gnlPro..         4884 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CMHPDAIK_1134.
ACCESSION   c01133_gnlPro..
VERSION     c01133_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 10:44:47
            Original ID  :: gnl|Prokka|CMHPDAIK_1134
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4884
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4884
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[337:4480]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      338..4480
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..4884
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4884
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(2..256)
                     /locus_tag="ctg1133_1"
                     /transl_table=11
                     /translation="MIGNYLIHAASSHAGERGFGFNDMSERHTAWVLSRLAIEMKEYPT
                     AFDKINLYTWIDEVGRLFTSRCFELADENGKTFGFARSIW"
     CDS             complement(338..892)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1133_2"
                     /sec_met_domain="ALS_ss_C (E-value: 4.9e-18, bitscore:
                     53.4, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKKLYTVIIFSENIVGLLNQITIIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDMIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEGLIRKYNARILEMNETCVVLEKSGHYDETQALFNELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLADMERKLQEKQQ"
     CDS             complement(908..2611)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1133_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 7e-51, bitscore:
                     160.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LRHVLVRHEQGATHAAQGYARVSGKVGVTLVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRKPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGLVDYEYKKVDYVRSYQPEPDIKKDRIKAAADLINEAKKPFCLVGQGVLLGG
                     AEEELKAFLQKNDIPAGSTVLGLSALPTDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFDRDEKEEYDKVIEKELYPTEGQLKMGEVVRKVSEATGNDAVLVTDVGQNQM
                     MGVRYFKYKQTRSVVTSGGLGTMGFGLPAAMGAKFGAPDRTVCFFTGDGGMQMTIQELG
                     TIMQEKLNVKIIILNNNFLGMVRQWQELFFHERYSNTIMENPDFVAIAKAYGIASRAVE
                     KREELDDAIAEMLNHDGAYVLVANVETCGMVYPMVPAGGSVTNMIMGDEK"
     CDS             complement(2645..4480)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1133_4"
                     /sec_met_domain="ILVD_EDD (E-value: 3.3e-217, bitscore:
                     710.1, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNPLRSSFSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSFT
                     QFVPGHTHLHEIGQLVKAEIEKQGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTVFVSGGPMEAGELDGRHLDLID
                     AMIESADTSVSDERIEQVERHACPGCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     KNRIQLFRDAAKQIVENAYKYYRDGDDSVLPRNIATRQAFLNAMSLDIAMGGSTNTVLH
                     LLAVAQEASADFHMEDIDMLSRKTPCLCKVAPNTHTYHVQDVNRAGGILGIMNELMKAG
                     LVDGSTRRADGLTLAEAVDKYAVTSPNVTEEAIRKYKSAPAHRFSIQMGSQESYYKELD
                     TDRAEGCIRDVEHAYSKDGGLAVLRGNIALDGCVVKTAGVDESIWKFSGPAKVFDSQDA
                     ACEGILGGKVVSGDVVVITYEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHISPEAASGGAIGLVRDGDIIEINIPERSINVRLSDEELAERRKAEEARGKK
                     AFTPPMRQREVSKALRAYGKMVSSADKGGVRIVED"
ORIGIN
        1 cccaaataga acgggcgaat ccaaaggttt tcccattctc atccgccagc tcaaaacaac
       61 ggctggtgaa aagacgtccg acctcatcga tccaagtgta taaattaatc ttatcgaagg
      121 cggtaggata ttccttcatc tcgatagcca gacgggacaa cacccaagcc gtatgacgct
      181 ccgacatatc attgaaaccg aacccacgct ctccggcatg gctggaagcg gcgtgaatca
      241 aatagttacc aatcataggg agcgttacac gtcccctaaa atccatcaaa tatggctccg
      301 ccacgaaatg aaataatcct actttctcga tatcttatta ttgttgcttt tcctgtaact
      361 ttcgctccat atcggccaac atatcgctca agcgctccac cttgctcttc gtgatagcca
      421 cacgtccgga gcggatgaat tgcaggacac cgatcgtctc gctcaactca ttgaacaagg
      481 cctgtgtctc gtcatagtgg ccactcttct ccaataccac gcaggtctcg ttcatctcca
      541 agatacgggc gttgtattta cggatcaatc cctccacggt tcccatcttg atgaaaagct
      601 cggtacttag cttataaaga gcgatctctt gataaaccag atcctcatcc gtattataat
      661 aagccttcaa gatatccaca cgtttatcga tctgtttcac caccttatcg atcatatcct
      721 catcggcgaa tgtcgtgatc gtaaacttat ggatgccctt gatagcggac ggagagacgg
      781 acagagtctc gatgttcagc tgtcggcgtg taaagataat cgttatctgg ttcaaaagac
      841 ctacgatatt ctctgaaaag ataataacgg tatataattt ctttgttgtc atagcttcat
      901 ctcctcctta tttctcgtct cccataatca tgtttgtcac gcttcccccg gcaggaacca
      961 tcggatacac cattccgcaa gtctccacgt tagcgaccaa cacgtaagcg ccgtcgtggt
     1021 ttagcatctc ggcgatagcg tcgtccaatt cctcccgctt ttcaacggca cggctggcga
     1081 taccataggc tttagcgatc gccacgaaat ccggattctc catgatggtg tttgaataac
     1141 gctcgtggaa gaacaattct tgccactgac gtaccatacc taagaagtta ttattaagaa
     1201 taataatctt cacgttcagt ttctcctgca tgatggtacc caattcctga atcgtcatct
     1261 gcataccccc atcaccggta aagaagcaga ccgtacggtc tggagccccg aacttagcgc
     1321 ccatagcggc cggcagacca aatcccatcg tacctaaacc accggaagtc accacgctac
     1381 gggtttgttt atatttgaaa tagcggacac ccatcatctg gttctgccca acgtcggtca
     1441 ccaatacagc gtcgttaccg gtcgcctcgg aaaccttacg gactacctcg cccattttca
     1501 gttggccctc ggtcggatac aattccttct cgattacctt atcgtattcc tctttctcgt
     1561 cccgatcgaa ctcggcattc cattccggac gtttacgttc ttccaacaac gccgtgatca
     1621 tcggtatcgt gtgcttggca ttacccagca cctttacatc tacggggacg ttcttaccga
     1681 tttccgagtt gtcgatatcc agatggataa tcttggcttg cttagcgtat gtctttaaat
     1741 cgccagtcac acggtcgtcg aaacgcatac cgatagcgat caatacatca cactcattcg
     1801 ttttccggtt cggccctacg tttccatgca taccgagcat tcccttgttc aatgggaaat
     1861 cggttggcaa cgcagataag cccaataccg tagatccggc aggtatatca ttcttttgga
     1921 gaaacgcttt caattcctct tccgcaccgc ctaacaatac tccctgcccg accagacaga
     1981 agggtttctt cgcctcattg attaaatcgg cggcggcctt gatacgatcc tttttgatat
     2041 ccggctccgg ctgataacta cgtacgtaat ctaccttctt atattcatag tccaccagcc
     2101 ctacttgcgc gtccttcgct aaatccagca caactggacc cggacggcct gtagaagcga
     2161 tataaaaagc acgagaaaca gcccatgcga tctcctccgg cttgcggatt tgataagccc
     2221 atttcgtgat cggttgcgtg atgccaatca cgtcgacttc ctgaaaagca tcggttccca
     2281 acaacggcga gggtacttga ccggcgatta cgaccattgg cgtactatcc atcagcgcgt
     2341 cagcgatacc cgtgatggta ttcgtagcgc ccgggccgga agtaaccaac gtcactccta
     2401 ccttgccgga tacacgagca tagccttgag ccgcatgggt agcgccttgc tcgtggcgca
     2461 ccaatacatg cctcaactgg tccctataat catataaact gtcgtaaata ggtatcgcct
     2521 gtccgccggg ataaccgaag atagtatcta ctccttcagc aatcaacgct ttcagcaaag
     2581 cttccgaacc ggttatcttt tgtttctcca taagaaataa cgtgtttaat gtatattatt
     2641 ggctttaatc ttcaacaatc cttacacctc ccttatcggc ggagctaacc atcttcccgt
     2701 acgctctcaa cgctttcgat acctcacgct gacgcatcgg cggcgtaaag gctttctttc
     2761 cacgcgcctc ttccgcttta cggcgctcgg ccaactcctc gtcgctcagc cgcacgttga
     2821 tggaacgttc cgggatattg atctcgatga tatccccgtc tctcaccagt ccgatagcgc
     2881 caccggaagc ggcctcagga gagatatgcc cgatagaaag accggacgta ccgccactga
     2941 aacgaccatc cgtgatcaag gcgcactcct tacctaagtg acggctcttt atataagagg
     3001 taggatataa catctcttgc attcccggcc ctcctttcgg accctcatac gtgatgacga
     3061 ccacatcgcc tgaaacgacc ttgcctccta aaatgccctc gcaagcggca tcctgtgaat
     3121 cgaagacttt cgccgggccg gagaatttcc aaatactctc atccacgccg gcggttttta
     3181 cgacacatcc gtccaaggcg atattccctc tcaaaacagc caagccgcca tccttggaat
     3241 aagcgtgctc cacatcacgg atacaacctt cggcacgatc cgtatctaat tccttataat
     3301 aagattcttg ggaacccatc tggatactga accgatgagc gggagcgctc ttgtatttac
     3361 ggatcgcctc ctccgttacg ttcggggaag tgacggcgta tttatcaaca gcctcggcca
     3421 aggtcaggcc gtccgcacgt ctcgtgctgc catccacaag cccggctttc atcaactcgt
     3481 tcatgatacc gaggattcca ccggcacggt ttacgtcttg tacatgataa gtgtgcgtat
     3541 tcggggctac cttacacagg caaggtgtct tgcgggataa catatcgata tcctccatat
     3601 gaaaatcggc actggcttct tgtgccacgg ccaataagtg aagcaccgta ttggtagacc
     3661 cccccatggc gatatccagc gacatggcgt tcaagaaagc ctgacgggta gcgatgttgc
     3721 gaggtaacac ggaatcatcc ccgtcacgat agtatttgta agcgttctca acgatttgct
     3781 tagccgcgtc acggaaaagt tggatacggt tcttatgggt agccacgatc gtcccgttcc
     3841 ccggaagcgc cagaccgatc gcctcgttca agcagttcat agagttagcg gtaaacatac
     3901 cggaacaaca accgcaaccc ggacacgcat ggcgttccac ctgctcgata cgctcatcgc
     3961 ttaccgatgt atcggcggac tcaatcatcg cgtcgatcaa atccagatgg cggccatcca
     4021 gctcacctgc ctccatcggg ccaccggaca cgaacaccgt cgggatattt aatcgcatgg
     4081 aagccataag catacccggc gtgatcttat cgcaattgct gatgcaaacc atagcgtccg
     4141 ccttatgggc atttaccata tattccacgc tgtccgcgat aatgtcgcgt gaaggaagcg
     4201 agtaaagcat cccatcgtgc cccatagcga taccgtcatc gatagcgatc gtattaaatt
     4261 cagcggcgaa acaaccttgt ttctcgatct cggccttgac cagttgcccg atctcatgca
     4321 aatgcgtatg ccccggcacg aactgggtaa atgaatttac gatagcgata ataggcttgc
     4381 cgaactgttc ctctttcatc ccgttggcac gccatagcgc acgggctccg gccatcctac
     4441 gaccttcggt gctaaatgag cttcttaacg gattcttcat ctctttccta ttttttgttc
     4501 gtagagcgct ttatccacgc ctctaccttg aattatttat aataaaaaaa gcctttccct
     4561 atatggagaa aggcttaaga aatatctcta cgacttcaca acttcttaca cacctttctc
     4621 cttacctact aatgactaga aggaccacca cgagaataat atgcaatacg ttgttcatca
     4681 tcttttctta ttgtctttgt ttgtttgact ctgcaaatgt agaacaataa ttgatatgcg
     4741 caaaggattt aaaagaaaat tctttatttt tctttcaatt ctcaagcaaa tatcatttta
     4801 ggattgcatt ttaacaggag caagagtgta ttacttagga atcggaaggt atagaagaga
     4861 aaaaacttcg atttcctact aagg
//
