LOCUS       c00045_gnlPro..        13466 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HCKKCODJ_45.
ACCESSION   c00045_gnlPro..
VERSION     c00045_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 10:11:52
            Original ID  :: gnl|Prokka|HCKKCODJ_45
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13466
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13466
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6281:10628]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      6282..10628
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..13466
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13466
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(98..799)
                     /locus_tag="ctg45_1"
                     /transl_table=11
                     /translation="MATLQHTDELYHILEDEICALKILPGEALSENQLCKRFGVSRTPI
                     RSVLQRLEQNRFVQIIPCKGTIVTAIDTGVVDQLIFQRVAVEGMVFRDFVQSCSPMEIL
                     AVEHLYNMLLEAAAGRSDPENFDFNHFLSCDLAMHEYWFHKTSKEYLWEQMTRPQADYS
                     RFIRLDIVGARNVSSVVSEHAEMLRILREKDLDAIEPLMRTHLYGGVSRMGSKIYSDEY
                     RGYFKLPENKK"
     CDS             1274..2071
                     /gene_functions="resistance (resist) AAC3 (Score: 107.1;
                     E-value: 5e-33)"
                     /gene_kind="resistance"
                     /locus_tag="ctg45_2"
                     /transl_table=11
                     /translation="MAYTKADLKHDLAAMGLTGNETILIHSSMKSIGPVEGGADTVLDA
                     WMEFFAEGLLLLPTHTWRFINEENRVFDVRRSPCCVGILPELFRHRPGVVRSLHPTHSM
                     AAYGKGAAAYLEGELDANTPCTPGGCYDRLRAAHGKVLLLGVTHARNTFIHSVEEVLNV
                     PNRLTDKPLQLTVVDEAGAQHTVYMRRHYNAQQPHISEDFVKLEQAYLDCGAARNTKFG
                     DASCILCDAGGLFRVTRHVLAPNPEAFVTEPVIPPERWQGGIL"
     CDS             complement(2119..3051)
                     /locus_tag="ctg45_3"
                     /transl_table=11
                     /translation="MAYQTSCASYTSGRVGLSSATAVVADAAGREQTQHGSPLFPIACY
                     AEDLSCFSVAWHWHEEFEFILAALGPIHVDVNKTRLTLQTGQGVFINSGALHAVEPAEG
                     RALLHSGVFQPRLIGGMDTVFWQKLIRPLLQPGTPPFFLLDEAVPWQRQVLLCLREAWK
                     SVADEPFDYENRVRYHLTAALRLLITQCVSGKVKVSEQEQIASERMKQMLRYVEEHYAE
                     ELTVEKLADCVALSESACLRSFRQFLGITPIQYVKQFRVEKAAELLRSTRLKTGEVGLE
                     CGFSDASYFIKTFREIKHCTPREYRIRFC"
     CDS             3321..3575
                     /locus_tag="ctg45_4"
                     /transl_table=11
                     /translation="MLRIEYFDKERFMRQLSASHGSVLLHLDNGKTCDLKKDTTARSML
                     QMMDTAPQKGFDLTVTDPADVTGFLRYMLEAGRTERVAG"
     CDS             3736..4374
                     /locus_tag="ctg45_5"
                     /transl_table=11
                     /translation="MNLKEAFRYQNKLQSLLDEAQGILDCDANVTKVANTYLRHKVMPE
                     AEDETVMDVAQTEYAEQITDVARFMLYLLEEKSRLFAAIRKAKDALDMDMDSEVSLNAA
                     RQSIARTFKRMNDLRSSEQLLSGGGTGYRFNAEGNQISYCCDVKRVTTINYDRKVIHAA
                     LSKLNRQADETSNRLDICLVTSKVDYTVPFDVNASFAEAFETYLENVKN"
     CDS             4789..4944
                     /locus_tag="ctg45_6"
                     /transl_table=11
                     /translation="MKRYKLFYLIGLLFFLAAALNFVTGGDHATAVVWRCLGATFLLLG
                     CSQQKK"
     CDS             5058..5834
                     /locus_tag="ctg45_7"
                     /transl_table=11
                     /translation="MSTKTIDSTATTRFDLSAAALHILAMALMLMDHLWATLLPAQEWL
                     TCAGRVAFPIFAFMAVEGYFHTHDLKKYTLRLLLFALLSEIPFDLMYGGTWFYPVHQNV
                     IWTLLLGILGIHLMETVRKKQKTGLYLLVSALVVVAGAVLGTLGMVDYYGAGVLTVFIF
                     YFFHGHGRKWWCLLGQLAALYWVNVELLGGLMYPIQLFGMDFELCQQGLALLALVPIWL
                     YRGRQGYHSKPFQYACYAFYPVHMLLLVLVLNFVNR"
     CDS             6282..9221
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_8"
                     /sec_met_domain="HGD-D (E-value: 9.5e-16, bitscore: 47.9,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 4.6e-39, bitscore:
                     124.0, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRVGLDIGSTTIKCVVLGEHDELLYSTYERHYSHILEKAQELLRR
                     IDAEHLHGRKALLSISGSAGMGLADSCGVPFVQEVFSTRVAVKRFMPKTDCVIELGGED
                     AKILFLTNGTEVRMNGSCAGGTGAFIDQMATLLKMSAGEMNKAAEQAQRTYTIASRCGV
                     FAKSDVQPLINQGARTEDIAASIYKAVVNQTIAGLAQGRPIKGNILYLGGPLTFSTVLR
                     KSFDEALNVTGICPENSLLYVALGAALYADKEFVLTEVAAALDKYAATATYASEPPLFA
                     SKEEYEAFHARHMSHSVPRVAFSAHCGPVHIGIDSGSTTVKLVVVDEKSQILYTNYQPN
                     LGNPLPLIREQLLKLYKEHPGLQVASVTTTGYGEELVKNAFRCDYGLVETVAHFTAAKY
                     FMPDVDFIIDIGGQDMKCFKIEDGAISNIFLNEACSSGCGSFLQTFAQALGYDVKEFAA
                     LGLFADRPVDLGSRCTVFMNSSVKQAQKDGASIENISAGLSISVVKNALYKVIRASSPE
                     ELGRKIVVQGGTFYNEAVLRAFEKEMGVEVIRPDIAGLMGAYGAALYGLRQSHKNNQTT
                     SAMMDEQELEKFAQQVVSVKCGGCGNHCQLTVNTFADGRKFISGNRCDKPVTGKSEDNS
                     LNLYAYKQQLLASYKPVPGKRGSIGIPMCLGFYELLPFWYAFWTSLGFAVHTSPVSTRG
                     LYLAGQATIPSDTACFPAKLSHGHIKALSQMQLDAIFYPCLTYNVDEGLGDNHYNCPVV
                     AYYPEVLAGNCPELEGKKFIYDYVGIHRPKDFVHKMAKEVLPKYFGGISEREVQAAADA
                     AYAEYEAHMAKIRVKGSEIIDEARRQGKRIIVLAGRPYHVDPEVNHGIDHLITRHGAAV
                     VTEDSISNRVQKFPTSVLNQWTYHSRLYAAAKYCTTQKDMDLVQLVSFGCGVDAITTDE
                     TREILQRGNKLYTQLKIDEITNLGAVNIRLRSLFAALDERDEAAAEKSE"
     CDS             9312..10628
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_9"
                     /sec_met_domain="HGD-D (E-value: 4.6e-22, bitscore: 68.7,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYHYPKFTPEMKKTHTILIPNMAVTQFRLMEYALRCEGYKCELL
                     GNCGSAVAQLGLKYVHNDTCYPALLVIGQFLDALNSGKYDLEHTALLITQTGGGCRASN
                     YIHLLRKALVKAGYPQIPVASLNFSGLEKDSGFQMTLPLARKCIACIFYGDMLCALRNQ
                     VAPYENEKGAADRMVDRWIARLGRALLAGKGFTSREMKHTFPLIAKEFATIPVTRVPKV
                     KVGVVGEIYVKYSPLGNNELQKFLESQDCEVNFPGLMGFVQYCAFNMGEDHVLYGGKLA
                     VKVGTDQFLNWLDSVERVMLKAETAAGFYAPGPFKELVKKPKGVISLGAKMGEGWLLTA
                     EMIELVQGGYGNIVCAQPFGCLPNHIVGKGMVNKIRALYPSANITPIDYDPSATRVNQE
                     NRIKLMLAVAKERLNAPAEAQPLTAEQLAGGAPQVGVTV"
     CDS             10712..11617
                     /locus_tag="ctg45_10"
                     /transl_table=11
                     /translation="MEKPAAACYHLPGLFEFYELYRRFLPLYREHREYFYDWCSIGSIY
                     GAPAGCIWGGGRISSGGAAAREVLALLREYGISGRLTFSNSLLRAEHLADPQCNALCDQ
                     FAKSGSVPNGVIVHSDLLADYLRQRWPELYLVSSTTKVLTEFAQLRQELAKPQFRYVVP
                     DFRLNPALEQLRTLPPEQKAKVEFLCNECCWFGCTERKRCYETVSRQNLGEDCPDHRCA
                     APDAAGGYRFSKAMRSPGFIGTDDIRQRYLPAGFSQFKIEGRGLGSALVLEFLLYYMIK
                     PEYQLQVREEIYLDNMLDLF"
     CDS             11747..13465
                     /locus_tag="ctg45_11"
                     /transl_table=11
                     /translation="METTQKQIVLGILAHVDSGKTTLSEAMLYRAGAIRKLGRVDHGDA
                     FLDTDSLEKARGITIFSKQALLTAGNTAITLLDTPGHVDFSTETERTLQVLDYAVLVVS
                     GTDGVQSHTETLWRLLRRYHVPTFVFVNKMDLPGMTREQLLSQLNHRLGEGFVDFGAGP
                     AARNEALALCDEQLMEKMLDAGTLTDADIIPAVARRHVFPCWFGAALRLDGVDALLEGL
                     DRYTRPAPALHAFGARVFKVSQDEQGARLTWLRVTGGELKVKTLLTGEADGEPWAEKAN
                     QLRLYSGAKYTLSEAIGPGQVCAVTGLTHAKPGTGLGAERDSDVPVLEPVLSYQVLLPE
                     GADVHAALGKLHRLEEEEPQLHVVWNESLGEIHVQLMGEVQLEVLRSLLAERFGLEVSF
                     GPGGILYKETITEPMEGVGHYEPLRHYAEVHLLLEPLPRGSGMQFAADCREEVLDKNWQ
                     RLVLTHLEEKQHLGVLTGAPLTDVKITLLTGKAHLKHTEGGDFRQATYRAVRQGLMLAK
                     SQLLEPWYAFRLEVPAENIGRAMSDIQRMEGSFDPPESGAETATLTGFAPVSTMRS"
ORIGIN
        1 gtaaggcagg ggactttgac tcccccatcg taggttcgac tcctgctggc gcaaccagaa
       61 gaaggccgct gcacagtttc ctgtgcagcg gccttcttta ttttttgttc tccggcagct
      121 tgaagtagcc gcggtattcg tccgagtaga tcttgctgcc catacggctc acaccgccgt
      181 acaggtgggt gcgcatcagc ggctcgatgg cgtccagatc cttctcacgc aggatgcgca
      241 gcatctcggc gtgctcgctg acgacgctgg acacgttgcg tgcgcccacg atgtccagac
      301 ggataaagcg ggagtagtct gcctgcgggc gggtcatctg ctcccaaagg tactccttgc
      361 tggtcttgtg gaaccagtac tcgtgcatgg caaggtcgca gctgagaaag tggttgaaat
      421 caaagttctc cgggtcgctg cgccctgcag cggcttccag cagcatatta taaaggtgtt
      481 ctaccgcaag aatctccatg ggcgagcagc tctgcacaaa gtcccggaac accatgccct
      541 ccactgcaac acgctggaag atgagctggt ccaccacgcc ggtgtcgatg gcggtaacaa
      601 tggtgccctt gcagggaatg atctgcacaa agcggttctg ctccagccgc tgtaaaacgc
      661 tgcggatagg agtgcgcgaa acgccgaacc gcttgcacag ctggttttcg ctcagcgctt
      721 ccccgggcag gatcttcaac gcgcagatct cgtcctcgag aatatgatag agctcatcag
      781 tgtgctgtaa tgtagccata gttgttctcc atttatccgg taaatgtaat cttagtatca
      841 ttgtaccgtt acagcaactg aatgtcaatg ctggaatgga acttaatttg aatacttgta
      901 tacaagaatg cgcactcgcg cacggaactg ttcctgaaac tgaaaaactg atataccact
      961 ttgcaatgca ggaaaagtgc tgataaaatg ctgcaatcaa gtgactgttg taccaaatgc
     1021 acaaagaaaa caggaaacaa ctgtcaaatt gctataattg caaggcgctg tgcttgtttc
     1081 gcggtaacgc tgcgagatga tatgctgtat acaggatttt actaaaaaag ctgcaagggc
     1141 acacaccccg cagataccgg ctcgtctccg gcaaatacaa cagggtgttt gccttttttg
     1201 cgtgcgtgct tgctttgccg cacaaaaggc ggtaaactgg gtacagacaa aatgcccgaa
     1261 aaggagaaac gacatggcat acacaaaggc tgacctcaag cacgaccttg cagcaatggg
     1321 gctgacaggc aacgagacca tcctgatcca ttcctccatg aagtccatcg gcccagtgga
     1381 gggcggcgca gacacggttc tggacgcatg gatggagttt tttgcggagg gcttgctgtt
     1441 gctgcccacc cacacatggc ggttcatcaa cgaggaaaac cgggtgttcg atgtacgccg
     1501 cagcccgtgc tgcgtgggca ttctgccgga gctgttccgg catcgccccg gggtggtgcg
     1561 ctcgctgcac cccacccaca gcatggcggc ttacggcaag ggggcggctg cgtatctgga
     1621 aggggagttg gacgccaaca ccccctgcac tcccggcggc tgctacgacc ggctgcgggc
     1681 agcccacggc aaagtgctgc tgctgggggt cacccacgcc cgcaacacct ttatccatag
     1741 cgtggaggag gtactgaacg tgccgaaccg cctgaccgac aagcccctgc agctgaccgt
     1801 ggtggacgaa gccggggcgc agcacaccgt ctatatgcgc cgccactaca acgcacagca
     1861 gccgcacatc tcggaggatt tcgtcaagct ggaacaggcg tatctggact gcggcgcagc
     1921 ccggaacacg aaatttggcg atgcaagctg cattttgtgc gacgccgggg ggcttttccg
     1981 ggtcacccgc catgttcttg ccccgaatcc cgaagccttt gtcaccgagc cggtcatccc
     2041 gccggagcgc tggcaggggg gaattttata atgcaatgcc gggcagcttg cagctgcccg
     2101 gcatttttta ctttttgctc agcagaagcg gatacggtac tcccgagggg tgcagtgctt
     2161 gatctcccgg aaggtcttga taaagtagct ggcatccgaa aagccgcatt ccagccccac
     2221 ctcgccggtc ttgagccggg tggagcgcag cagctcggcg gctttttcca cccggaactg
     2281 cttgacgtac tggatgggcg tgatacccag aaactgccgg aaactgcgca gacaggcact
     2341 ttcgctcagg gcaacgcagt cggccagttt ttccacggtc agctcctcag cgtagtgctc
     2401 ctctacatag cgcagcatct gcttcatccg ctccgaggca atctgctcct gctccgatac
     2461 ctttactttg ccgctgacgc attgggtaat gagcagccgc agggcggcag taaggtggta
     2521 acgcacccgg ttctcgtagt cgaaaggctc gtccgccacg ctcttccacg cctcccgcag
     2581 gcagagcagc acctgccgct gccatggcac ggcctcgtcc agcaaaaaga agggcggtgt
     2641 gccgggctgc aagagtgggc ggatgagttt ttgccagaat acggtgtcca tgccgccgat
     2701 aagccgtggc tggaacacgc cggagtgcag cagcgccctg ccctcggcag gctctaccgc
     2761 gtgcagcgcc ccggagttga tgaacacccc ctgcccggtc tgcaaagtca gccgggtctt
     2821 gttcacatct acatggatgg gccccaacgc cgccagaatg aactcaaatt cctcgtgcca
     2881 gtgccacgcc accgaaaaac aggaaagatc ctcggcatag caggcaatag ggaacagcgg
     2941 gctgccgtgc tgggtctgct cccgcccggc ggcatcggca accacggcag tagcgctgga
     3001 cagccccacc cggccgctgg tataagaggc acagcttgtc tgatatgcca tattcaccaa
     3061 ttcctttccg caatactttg aatgtttttt gtcaatgccg gttttgttgc atatactatg
     3121 cggttttatt ctattattag cgattgtttt gtggtattat cctatcagag cttccaagct
     3181 cagtatagca ccaaggcagc ggggacgcaa gctgtgcaag cgtttccact gtcgggcaaa
     3241 actgccattc tcccgccgtc tatccaaaga ggactggacg gcaagtgtaa cataaaccat
     3301 ttcatcaagg aggtattcct atgcttcgta tcgagtattt tgataaggaa cgtttcatgc
     3361 gccagctttc tgccagccac ggcagcgtgc tgctgcatct ggacaacggt aagacctgcg
     3421 acctgaaaaa ggacactacc gcacgctcca tgctgcagat gatggacact gccccccaaa
     3481 agggctttga cctcaccgtg accgaccctg ccgacgtgac cggcttcctg cgctatatgc
     3541 tggaggcagg ccgcaccgag cgcgtggccg gctgagtaat gccaatctct tatcccaata
     3601 agtgtcacag caaatgcaaa gcgcccgtcc cggtcatgcc ggggcgggcg ttttgctcat
     3661 tttaccggaa ggcttgcgcg ggcgggcagt ctgtggtaag ctgaaaacag aaaaaacaag
     3721 atggagggaa cgactatgaa cctgaaggaa gcattccgct accagaacaa gctccagtct
     3781 ctgctggacg aggcgcaggg cattctggat tgcgatgcca acgtgaccaa ggtggccaac
     3841 acctatctgc gccataaggt gatgcccgag gccgaggacg agaccgttat ggacgtggca
     3901 cagaccgaat atgcagagca gatcaccgac gttgcccggt tcatgctcta tctgctggag
     3961 gaaaaaagcc gcctgtttgc cgccatccgc aaggcaaagg atgcgctgga catggatatg
     4021 gacagcgagg ttagcctgaa tgccgcacgg cagagcattg cccgcacctt caaacggatg
     4081 aacgacctgc gcagttctga gcagctgctc tccggcggtg gcaccggcta ccgcttcaac
     4141 gccgagggca accagatctc ctactgctgc gatgtgaagc gggtgaccac catcaactac
     4201 gaccgcaagg tcatccatgc ggcgctgagc aagctgaacc ggcaggcaga cgaaacctcc
     4261 aaccggctgg acatctgcct tgtgacctcc aaggtagact acactgtccc ctttgatgtg
     4321 aacgccagct ttgccgaagc ctttgagacc tatctggaaa acgtcaaaaa ctaaataaac
     4381 gttccaccgg ctattttggg tgcggcaagc gccaggtgca cagctgccgg ttcaggtgca
     4441 gatgaactat aacgctgcac atttccgcaa ggaagttttg gtacggctca ccttacgagc
     4501 cagctattat gaaaaaaatc ttgcgttcgg cttttccgcc accgccagac gctttttcgt
     4561 cgaaaccgtc ccttgctcct tcccgcattc ctgcttttgc gcttacgtct ccatgggcag
     4621 gcaggcaagc cacccttcat gaatttgccc cgcagactgc tgcgggcaca cactttctgc
     4681 gtgccgggcg ggcgctttgc gcccctgtgc acacaaaaaa tggcagccgt ccctgcgctt
     4741 gccgtatcca aaatagccgg tggaaaacca aaaccggagg tatgagctat gaaaaggtat
     4801 aagctgtttt atctcatcgg gctgctgttt tttcttgctg cggcgctgaa ctttgttacc
     4861 ggaggggatc acgctacggc agtggtatgg cgctgccttg gcgctacctt tttgctgcta
     4921 gggtgttcgc agcagaaaaa ataaagcagc aagccagccc cggcggtgga aaaatctggc
     4981 cggggctgca attctttgcg gggctcgttc gtattccaga cagaacgacc aaatttcgac
     5041 aaaaacgagg taggatcatg tcaaccaaaa cgatcgattc cactgccacg acccgctttg
     5101 acctgagcgc tgcggcactt catatccttg ccatggcgct gatgctgatg gaccacctgt
     5161 gggcgacgtt gctgccggca caggaatggc tgacctgcgc ggggcgggtg gcgtttccca
     5221 tctttgcctt tatggcggtg gagggctact tccacaccca cgacctgaaa aaatacacct
     5281 tgcgtctgct gctgtttgcc ctgctttcag agatcccctt cgacctgatg tacggcggca
     5341 catggttcta cccggtgcac cagaacgtca tctggacgtt gcttttgggc attctgggca
     5401 tccacttgat ggaaacggtg cgcaaaaagc aaaaaacagg actgtacctg ctggtatccg
     5461 cccttgtggt ggtggcgggc gcggtgctgg gcacgctggg catggtggac tactacggcg
     5521 caggggtgct gactgtgttc atcttctact tttttcacgg gcacgggcgc aagtggtggt
     5581 gtctgctggg gcagctggca gcgctgtact gggtcaacgt ggagctgctg ggcgggctta
     5641 tgtaccccat tcagctcttc ggcatggact ttgagctttg ccagcagggg ctggcgctgc
     5701 tggcactggt gcccatctgg ctgtaccgcg gtcggcaggg ctaccacagc aagcctttcc
     5761 agtatgcctg ctacgccttt taccccgtgc acatgctgct gctggttctg gtgctgaatt
     5821 tcgtgaaccg gtaaggaaaa cggaacgctc caaaaatatt ttacgcgcgg ggcgtagaga
     5881 ggaacttccg ctgaaaatag ccaaagcgca tgcggagcca ttcgaaatcg tcccgccggt
     5941 acaaggccgc tgcacaaagc gctgtgcggc ggcttttttt gcgggaaaac cgacacatgt
     6001 tcacaaaaag ttcagccttt tgagcaaaaa atactatttt tttcgtgtaa aatagacaac
     6061 atggattgaa tgccgcccgc gattggatta taataataat gtatgcaaaa gtgcatttgc
     6121 tgtgtttttt ataacgcgta ctgtttgaaa atgacgtaga tgcgcaatgc gggaagctaa
     6181 aaagaaaaaa cgccgttgcg ggtctttgcc gcaaacgact tgtttgccat agcagccggg
     6241 gcgttatgtt ccggttattt gtccttagga ggaaaaacaa ggtgagagta ggtcttgaca
     6301 tcggtagcac caccatcaag tgcgtggtgc tgggcgagca tgatgaactg ctgtattcta
     6361 catacgaacg acattatagt catattctgg aaaaggcgca ggagctgctg cggcgcattg
     6421 atgccgagca tctgcatggc cgcaaggcgc tgctcagcat ctccggctct gccggtatgg
     6481 gcttggccga cagctgcggt gtgccctttg tgcaggaggt attctccacc cgcgtggcgg
     6541 tcaagcgctt tatgccaaag actgattgtg tcattgagct gggcggcgag gatgccaaga
     6601 tcctgttttt gaccaacggc accgaggtgc gcatgaacgg cagctgtgcc ggcggcaccg
     6661 gtgctttcat cgaccagatg gctaccttgc tgaagatgag cgccggggaa atgaacaagg
     6721 ctgccgagca ggcgcagcgc acctatacca tcgcttcccg ctgcggcgtg tttgcaaaaa
     6781 gtgacgtgca gccgctgatc aatcagggtg cccgtaccga ggatatcgcc gccagcatct
     6841 ataaggccgt ggtcaaccag accatcgccg gtctggcaca gggacgtccc atcaagggca
     6901 atatccttta tctgggcggc ccgctcacct tcagcaccgt gctgcgcaag agctttgacg
     6961 aagcgctgaa cgtgaccgga atctgcccgg aaaacagtct gctgtatgtg gcgctgggcg
     7021 ctgcgttgta tgccgacaag gaatttgtgc ttaccgaggt ggccgctgcg ctggacaagt
     7081 acgccgccac cgctacctat gccagcgagc cgccgctgtt cgccagcaag gaggagtacg
     7141 aggctttcca cgcacggcac atgtcccaca gtgtgccccg cgtggctttt agtgcccact
     7201 gcgggccggt gcatatcggc atcgactccg gttctaccac cgtcaagctg gtggtggtgg
     7261 atgaaaagag ccagattttg tacaccaact atcagcccaa ccttggcaac ccgctgcccc
     7321 tcatccggga gcagctgctc aagctctata aggagcatcc ggggctgcag gtggccagtg
     7381 ttaccaccac tggctacggc gaggagctgg taaagaacgc tttccgctgt gattacggtc
     7441 tggtggaaac ggtggcgcat tttaccgctg ccaagtactt tatgccggac gtggatttca
     7501 ttattgatat cggcgggcag gacatgaagt gcttcaagat cgaggatggt gccatcagca
     7561 acatcttcct gaacgaggcc tgctcctccg gctgcggcag ctttttgcag acctttgcgc
     7621 aggcgctggg ctacgacgtc aaggagtttg ccgcgctggg tctgttcgca gaccgcccgg
     7681 tggacttggg cagccgctgc accgtgttca tgaacagctc ggtcaagcag gcgcagaagg
     7741 atggtgccag catcgagaat atctccgcag gcctgtccat cagcgtggtc aagaacgcgc
     7801 tgtacaaggt gatccgcgct tccagcccgg aagagctggg tcgcaagatc gtggtgcagg
     7861 gcggtacctt ctataatgaa gccgtgctcc gcgcctttga aaaggaaatg ggtgtggagg
     7921 tcatccggcc ggacattgcc ggtctgatgg gcgcttacgg cgctgctttg tacggcctgc
     7981 gccagagcca taaaaacaac cagaccacct ctgccatgat ggacgagcag gaactggaaa
     8041 agtttgcaca gcaggtggtc agcgtcaagt gcggcggctg cggcaaccat tgccagctga
     8101 ccgtcaacac ctttgccgat ggccgcaagt tcatctccgg caaccgctgc gataagcccg
     8161 ttaccggcaa aagcgaagat aacagcctga acctgtacgc ctacaagcag cagctgctgg
     8221 ccagctacaa gcctgtgccc ggcaagcgcg gttccatcgg tatcccgatg tgtctgggct
     8281 tctacgagct gctgcccttc tggtacgcct tctggacgag ccttggcttt gcggtgcaca
     8341 ccagcccggt gtccacccgc gggctgtatc tggccggaca ggctaccatc cccagcgata
     8401 ccgcctgctt cccggcaaag ctgagccacg gccacatcaa ggcgctgagc cagatgcagc
     8461 tggacgccat cttctacccc tgcctgacct acaatgtgga cgagggcttg ggcgacaacc
     8521 attataactg cccggtggtg gcctactacc cggaggttct ggcaggcaac tgcccggagc
     8581 tggaaggcaa aaagttcatc tatgattatg tgggcatcca ccgtcccaag gattttgtgc
     8641 acaagatggc aaaggaggtg ctgcccaagt actttggcgg catctccgag cgggaggtgc
     8701 aggccgcagc cgatgccgcc tacgcggagt atgaggcgca catggctaag atccgggtaa
     8761 agggcagtga gatcatcgac gaggcgcgcc gtcagggtaa gcgcatcatc gtgctggcag
     8821 gccgccccta tcatgtagac ccggaggtca accacggcat cgaccatctg atcacccgcc
     8881 acggggctgc ggtggtcacc gaggacagca tctctaaccg ggtgcagaag ttccccacca
     8941 gtgtgctgaa ccagtggacc taccacagcc gcctgtatgc tgccgccaag tactgcacca
     9001 cccagaagga tatggatctg gtgcagctgg tgtccttcgg ctgcggcgtg gatgccatta
     9061 ccaccgatga gacccgcgag attttgcagc ggggcaataa gctgtatacc cagctgaaga
     9121 tcgacgagat cacaaacctc ggtgccgtga acatccgtct gcgcagcctg tttgccgcgc
     9181 tggacgagcg ggacgaggcc gccgcagaaa agtcagaata aaagaaaccc tgagataggc
     9241 tgaagggctt cccccggcgg ggggaagtct ttgcggggac tatcttgttt agagcaacat
     9301 aggaggaacc tatggaatat cattatccca aatttacccc ggagatgaaa aagacccaca
     9361 cgatccttat ccccaacatg gccgttaccc agttccggct tatggagtac gcactgcgct
     9421 gcgagggcta caagtgtgag ctgctgggca actgcggcag tgccgtggca cagctggggc
     9481 tgaagtatgt ccacaacgat acctgctacc cggcgctgct ggtcatcggc cagtttctgg
     9541 atgcgctgaa cagcggcaag tatgatctgg aacataccgc gttgctgatc acccagaccg
     9601 gcggcggctg ccgcgcctcc aactacatcc atttgctgcg caaggcgctg gtcaaggctg
     9661 gatatccgca gatcccggtg gcaagcctga acttttccgg tctggaaaag gacagcggct
     9721 tccagatgac cctcccgctg gcgcgcaagt gcatcgcctg catcttctac ggcgatatgc
     9781 tgtgtgcgct gcgcaatcag gtagccccct acgagaacga aaagggtgct gctgaccgca
     9841 tggtggaccg ctggatcgcc cgtctgggcc gtgccttgct ggccggaaaa ggctttactt
     9901 cccgggaaat gaagcacacc ttcccgctga tcgcaaagga atttgccacc attccggtca
     9961 cccgggtgcc caaggtcaag gtgggtgttg tgggcgagat ctacgtcaaa tacagcccgc
    10021 tgggcaacaa cgaactgcag aagtttctgg aaagtcagga ctgcgaggtg aacttccccg
    10081 gtctgatggg ctttgtgcag tactgcgcct tcaacatggg cgaggatcat gtgctgtacg
    10141 gcggcaagct ggctgtaaag gtaggcaccg atcagttcct caactggttg gacagcgtgg
    10201 agcgtgtcat gctcaaggca gagacggccg ccgggttcta tgcgccgggc cccttcaagg
    10261 agctggtgaa aaagcccaag ggcgttatct cgctgggcgc aaaaatgggc gaaggctggc
    10321 tgctgaccgc cgagatgatc gagctggtgc agggcggcta cggcaacatc gtgtgtgcgc
    10381 agccctttgg ctgcctgccc aaccatatcg tgggcaaggg catggtgaac aagatccgtg
    10441 cgctgtaccc cagtgccaac atcaccccca tcgactacga tcccagtgct acccgggtca
    10501 atcaggaaaa ccgcatcaag ctgatgctgg ctgtggccaa ggagcggctg aacgcccccg
    10561 cagaagccca gccgcttacg gcagagcagc ttgccggtgg tgcccctcag gtcggcgtca
    10621 ccgtgtaaca aaagcaaata cgataaaaac aggggagccg ctgcacggca tttttacgca
    10681 gcagctccct ttttgcagga aaggaaccgc tatggaaaag cccgcagctg cctgttatca
    10741 tctgcccggc ctgttcgagt tttacgagct gtaccgccgt tttttgccgc tgtaccggga
    10801 gcaccgggaa tatttttacg actggtgcag cattggctct atctacggcg ccccggcggg
    10861 ctgcatctgg ggcgggggac gcatttccag cggcggggca gctgcgcgcg aggtgctggc
    10921 gctgctgcgg gaatacggca tctccgggcg gctgaccttc agtaactccc tgctgcgggc
    10981 ggagcacctt gccgatccgc agtgcaacgc cctgtgtgac cagtttgcaa aaagcggcag
    11041 tgtgccaaac ggcgtcatcg tccattctga tttgctggcg gactatctgc ggcagcgctg
    11101 gccggagttg tatctggtgt cctccaccac caaggtactc acggagtttg cgcagttgcg
    11161 gcaggaattg gcaaagccgc agttccggta tgtggtgccg gatttccggc tgaacccggc
    11221 actggaacag ctgcgcaccc tgccgccgga gcaaaaagcc aaggtggaat ttttgtgcaa
    11281 tgagtgctgc tggttcggct gcaccgagcg caagcgctgc tacgagacgg tcagccgtca
    11341 gaatctgggc gaggactgcc cggaccaccg ctgcgccgcc ccggatgccg ccgggggcta
    11401 ccgcttttcc aaggcgatgc gcagtcccgg gtttatcggg acggatgaca tccgacagcg
    11461 gtacctgccc gcaggctttt cccagtttaa gatagagggc agggggctag gcagtgcact
    11521 ggtgctggaa tttctgcttt actacatgat aaagccggaa taccagctgc aagtgcggga
    11581 ggaaatctat ctggacaata tgctggatct tttttaagaa aattgcaccg ggcagaccat
    11641 tttctgtccg gtgctgtttt ttgcttgtgg gatttgcaca tgaaaacttt cttttcccgg
    11701 caaagcgtgc tacaataaat gagaaacttt tttataggag cagtgcatgg aaacaacgca
    11761 aaaacagatc gtactgggca ttctggccca tgtggactcc ggcaagacca ccctctccga
    11821 ggccatgctc taccgcgcag gtgctatccg caagctgggg cgggtagacc acggagatgc
    11881 ctttctggac accgacagct tggaaaaagc gcgcggtatc accatctttt ccaagcaggc
    11941 gctgcttacg gcgggcaata ccgccatcac cctgctggac acccccggcc atgtggattt
    12001 ttccaccgag accgagcgca ccttgcaggt gctggattac gccgtgctgg tggtcagcgg
    12061 aacagacggc gtgcaaagcc ataccgaaac gctgtggcgg ttgctgcggc gctaccatgt
    12121 gcccaccttt gtattcgtga acaagatgga cctgcccggc atgacccggg aacagttact
    12181 cagccagctg aaccaccgcc ttggcgaggg ctttgtggat tttggcgcag ggcctgccgc
    12241 ccgcaacgaa gcactggcgc tgtgcgatga gcagctgatg gaaaaaatgc tggacgcggg
    12301 aaccttgacc gatgcggaca ttatccccgc agttgcccgg cggcacgtct ttccgtgctg
    12361 gttcggggcg gcgctgcggc tggacggggt ggatgcactt ttggaggggc ttgaccgcta
    12421 cacccgcccc gccccggcgc tgcacgcctt tggcgcaagg gtatttaagg tatcgcagga
    12481 cgagcagggc gcccgcctga catggctgcg ggtcaccggc ggagaactga aggtgaaaac
    12541 tctgctcacc ggcgaagcgg acggcgagcc gtgggcagaa aaagcgaacc agctgcggct
    12601 gtactccggc gcaaagtata ctctgtccga ggctatcggc ccgggacagg tgtgcgccgt
    12661 gaccggcctg acccatgcaa agcccggcac cgggcttggg gcagagcggg acagcgatgt
    12721 gccggtgctg gaaccggtgc tcagctatca ggtgctgctg ccggaggggg cggacgtgca
    12781 cgccgcgctg ggcaagctgc accggctgga ggaggaagaa ccgcagcttc atgtagtgtg
    12841 gaatgaaagc ttgggcgaaa tccatgtgca gctgatgggc gaggtacagc tggaagtgct
    12901 gcgcagcctg ttggcggagc ggttcgggct ggaagtgtcc tttggcccgg gcggtatttt
    12961 gtataaggag accatcaccg agcccatgga gggcgtaggc cactacgagc cgctgcgcca
    13021 ctatgccgag gtgcatctgc tgctggaacc gctgccccgg ggcagcggga tgcagtttgc
    13081 cgccgactgc cgggaagagg tgctggataa aaactggcag cgtctggtgc tgacccatct
    13141 ggaagaaaag cagcaccttg gcgttttgac cggcgcaccg ctgacggatg taaagatcac
    13201 tctgctcacc ggcaaagcac acctcaagca cactgagggc ggcgatttcc ggcaggccac
    13261 ctaccgcgcc gtgcggcagg ggctgatgct ggccaaaagc cagctgctag agccgtggta
    13321 tgccttccgg ctggaggtgc cggcggaaaa tatcggccgc gccatgagcg atatccagcg
    13381 catggagggc agctttgacc cgccggaaag tggcgcggag accgccaccc tgaccggctt
    13441 tgcgccggta tccaccatgc gcagct
//
