LOCUS       c00205_gnlPro..         4693 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HCKKCODJ_205.
ACCESSION   c00205_gnlPro..
VERSION     c00205_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 10:11:52
            Original ID  :: gnl|Prokka|HCKKCODJ_205
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4693
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4693
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:4691]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..4691
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..4693
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4693
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(3..1406)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg205_1"
                     /sec_met_domain="ILVD_EDD (E-value: 3e-190, bitscore:
                     621.2, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSDNVTKGSERAPNRSLFYALGYTPEELERPLIGVVSAYSEIVP
                     GHMNLDKIAEAVKAGVQMAGGTPILIPAIGVCDGIAMGHVGMKYSLASRELICDSVETM
                     LMAHQLDGLVLVPNCDKIVPGMVMAAVRMDVPAVVCSGGPMLAGTYGGEEVSLSKMFEA
                     VGAYKAGMITDEQLEDCTCNCCPSCGSCSGMYTANSMNCLCEAIGIALPGNGTIPAVYS
                     KRLQLAKHAGMAVMEMVRKGITARQIINERSIRNALTCDMALGCSTNTVLHLLAIAYEA
                     GVPIDLKLFNEISAKTPNLCHLAPAGPTHMPDLYAAGGIPAVQAELAKKGLLDLDVPTV
                     TGKTLGENIKGAHILNEKAIRPIENPYSETGGLQILWGNIAPDGCVVKRSAVAPEMQKH
                     AGPARVFNSEEEAIAAIYAGKIVPGDVVVIRYEGPKGGPGMREMLNPTSALAGMKLDKT
                     VALITDGRFS"
     CDS             complement(1573..2592)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg205_2"
                     /sec_met_domain="IlvN (E-value: 2e-75, bitscore: 240.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 3e-66, bitscore: 210.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIKKYYDSDCNLGVLDGKTVAVIGFGSQGHAHSENLAESGVNVV
                     VGLRKGSAHWAKASEFAATHDNFKVMEVEEAAKAGDVVMMLVPDELCADIYNTQVAPYM
                     TEGKALAFAHGFNIHFKTITAPKNVDVIMIAPKGPGHIVRRLYTEGEGCPSLICVEQDY
                     TGKAKDIALAYASGIGAGRAGILQTTFKEETETDLFGEQAVLCGGVSELIHAGFDTLVE
                     AGYEPEMAYFETCHEMKLIVDLINEGGFSKMRYSISNTAEYGDYRTGKRLITEETRKEM
                     KKVLTEIQDGTFASEFLTEMSPKGGRKVHFLAKRRMEAELPIEKVGAELRSMMSWLKK"
     CDS             complement(2691..3254)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg205_3"
                     /sec_met_domain="ALS_ss_C (E-value: 5.1e-29, bitscore:
                     88.6, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESDQRRVISLLVDNQSGVLARVSSLFCRRGFNIDSLTVSATNDP
                     AVSRITVTITSDEKALQQLVLQTERLEVTRQVFVLDSEKSLERELLLLKVESDVHNRTE
                     LREIACIYKAKIIDLSPDSMVFELIGRPDKLDAFLKMFEGYNILEQCRTGVTALERGGM
                     HQHIQKPPQEVRSVQLPPPGARRA"
     CDS             complement(3270..4691)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg205_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5e-52, bitscore:
                     163.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LVTGIATAYMDSVPMVAFTGNVPTSSIGKDGFQEAYIEGITVPIT
                     KHNFTVRRVEDLADTMRAAFRIAQSGRKGPVLVDIPKDVTAAVCEFTPKQPEPIRTVTT
                     YNEEQVHWAADLINAAQRPLVYFGGGVRSAASCQPLRDLLHKAEIPATYTLMAAGVVPY
                     GDPMNLGMLGMHGCYTSNRAVAECDVLIAVGTRFSDRVALNPKTFAKNATIIQIDIDAS
                     ELGKNVDVDLSIVGDAAYVLNAMLPQIKPAKHPEWMTMIQSWQAQDYHPVSDPTRLMPH
                     QVIGEVCNQCGPDAVYVTDVGQHQMWAAQYLRHTKSRGFITSGGLGTMGFGYGAAIGAQ
                     MALGRQQRVVMFTGDASFHMNLNEACTAVSYELPIITVIFNNSVLGMVRQWQTSFYGKR
                     YSQTDPHRKTDFVKLADGFGLKGYRCTNLPEFQEAFADALQQKGPTWIECIVDKDEKVL
                     PMIPGGGDINDIIME"
ORIGIN
        1 ccggagaagc ggccgtccgt gatgagggct accgtcttat ccagcttcat gcctgccagc
       61 gcagaggtgg ggttgagcat ctcccgcatg cccgggccgc ccttggggcc ttcgtagcgg
      121 atgaccacca catcgcccgg gacgatcttg cctgcgtaga tggcggcaat agcttcctcc
      181 tcgctgttga acacccgcgc cgggcctgcg tgcttctgca tctccggggc gacggcgctg
      241 cgcttgacca cacagccgtc cggggcaatg ttgccccaca ggatctgcag accgccggtc
      301 tcagagtagg ggttctcgat gggacggatg gccttttcgt tcaggatatg ggcacccttg
      361 atgttctcgc caagggtctt gccggtgacg gtgggcacgt ccaagtccag caggcccttc
      421 ttggccagct ctgcctgcac cgccgggata ccgcccgctg cgtacagatc cggcatgtgg
      481 gtggggcctg ccggtgccag atggcacagg ttgggggtct tggcgctgat ctcgttgaac
      541 agcttcaggt cgatgggcac accggcctcg taggcgatag ccagcaggtg cagcaccgtg
      601 ttggtggagc agcccagcgc catatcacag gtcagcgcgt tgcggatgga gcgctcgttg
      661 atgatctggc gcgcggtgat gcccttgcgc accatctcca tcactgccat accggcgtgc
      721 tttgccagct gcaggcgctt ggagtacaca gccgggatgg tgccgttgcc gggcagtgcg
      781 atgccgatgg cctcacacag gcagttcatg ctgttggcgg tgtacatacc ggagcagctg
      841 ccgcagctgg gacagcagtt gcaggtgcag tcctccagct gctcgtcggt gatcataccg
      901 gccttatagg cacccacggc ctcgaacatc ttggaaaggc tcacttcctc gccgccgtaa
      961 gtaccggcca gcatggggcc gccggagcag accacggcgg gcacatccat gcgcaccgct
     1021 gccatcacca tgccgggcac gatcttatcg cagttgggca ccagcacaag gccgtccagc
     1081 tggtgtgcca tcagcatggt ctccacgctg tcgcagatca gttcacggga ggccaaagag
     1141 tacttcatgc ccacatgacc catagcgatg ccatcgcata caccgatggc ggggatcagg
     1201 atgggggtac caccggccat ctgcacaccg gccttgacag cctcggcgat cttatccaga
     1261 ttcatgtgtc cgggcacgat ctcgctgtag gcgcttacca cgccgatgag ggggcgctcc
     1321 agctcctccg gggtgtagcc cagcgcataa aacaggctgc ggttgggcgc gcgctccgag
     1381 cccttggtca cgttgtcact tctcattgca aatcctcttt tctgataaag ccctctccgt
     1441 cacggctgcg ccgtgccacc tctcccgagg gggagaggtt ttcgcggagg agctataagg
     1501 ttcccttttc aacaaaaact ccccctttcg ggggagctga ccgctgaaaa gcggtctgag
     1561 agggtttccc tcttacttct tcagccagct catcatgctg cgcagctcag cacccacctt
     1621 ctcgatgggc agctcggcct ccatacggcg cttggcaagg aagtgcacct tgcggccgcc
     1681 cttggggctc atctcggtca ggaactcgga agcaaaggtg ccgtcctgga tttcggtcag
     1741 aaccttcttc atctccttgc gggtctcctc ggtgatcagg cgcttgccgg tgcggtagtc
     1801 gccgtactca gcagtgttgg agatggagta gcgcatcttg gagaagccgc cctcgttgat
     1861 caggtcaacg atcagcttca tctcgtggca ggtctcaaag taggccatct cgggctcgta
     1921 gccggcctcc accagcgtat cgaaaccggc gtggatcagc tcggaaacgc cgccgcacag
     1981 cacggcctgc tcgccgaaca gatcggtctc ggtctcctcc ttgaaggtgg tctgcaggat
     2041 gcctgcacgg ccagcgccga tgccggaagc atatgccaga gcaatatcct tagccttgcc
     2101 ggtgtagtcc tgctccacgc agatcagaga ggggcagccc tcgccctcgg tgtacaggcg
     2161 gcggacgatg tggccggggc ccttgggagc gatcatgatg acgtccacgt tcttgggagc
     2221 ggtgatggtc ttgaagtgga tgttgaagcc gtgtgcaaag gccagtgcct tgccctcggt
     2281 catgtaggga gcaacctggg tgttgtagat atcggcgcac agctcatcgg gcaccagcat
     2341 catgacaaca tcgccggcct tggcagcctc ttccacctcc atgaccttga agttgtcatg
     2401 ggtggcagcg aactcagaag cctttgccca gtgagcagaa cccttgcgca ggccgaccac
     2461 aacgttgacg ccgctctcag ccagattctc agagtgtgca tgaccctggc tgccgaagcc
     2521 gatgacagcg acggtcttgc cgtccagcac gccgaggttg cagtcggaat cgtagtattt
     2581 cttgatagcc ataatcgtta gtctcctttt acattaactg gttggtttat cttccggtct
     2641 tgtatgctct gttctatctt tcgctcatcc tgagcggaaa agcaatgtaa ttatgcccgt
     2701 cttgcgcccg gcgggggcag ctggacggag cgcacctcct gcggcggctt ctggatatgc
     2761 tggtgcatcc cgccgcgctc cagtgcagta acgccggtgc ggcactgttc aaggatgttg
     2821 taaccctcga acattttcaa aaatgcgtcc agcttgtccg gccggccgat caactcaaac
     2881 accatactgt ccggggaaag atcaatgatc tttgccttgt agatgcaggc gatctcccgc
     2941 agctctgtgc ggttgtgcac gtccgattcc accttgagca gcagtagctc ccgctccagc
     3001 gatttttcgc tgtccagcac gaacacctgc cgggtgactt ccagacgctc ggtctgcaat
     3061 accagctgct gcaaggcctt ttcatcgctg gtaatggtca ctgtgatgcg gctgactgcc
     3121 gggtcgttgg tggcggacac cgtaaggctg tcgatattga agccgcggcg gcagaacagg
     3181 ctggacaccc gggccagaac gccgctctgg ttgtccacca gcaggctgat gaccctgcgc
     3241 tgatcagatt ccatgatgct gtgtcctcct tattccatga tgatgtcgtt gatatcgccg
     3301 ccgccgggga tcatgggcag caccttttcg tctttgtcga cgatgcactc gatccaagtg
     3361 gggcctttct gctgcagggc atctgcaaag gcttcctgaa actccggcag gttggtgcag
     3421 cggtagccct tcaggccaaa gccgtctgcc agcttgacaa aatcggtctt gcggtggggg
     3481 tcggtctggc tgtaacgctt gccgtaaaag ctggtctgcc actggcgcac catgcccagc
     3541 accgagttgt tgaagatgac cgtgatgatg ggcagctcgt agctgacggc ggtgcaggct
     3601 tcgttcaggt tcatgtggaa ggaggcgtca ccggtaaaca tcaccacacg ctgctggcgt
     3661 cccagtgcca tctgggcacc aatggcggca ccgtagccaa agcccatggt gccaaggccg
     3721 ccgctggtga taaagccgcg gctcttggtg tggcgcaggt actgtgctgc ccacatctgg
     3781 tgctgaccca catcggtaac atacacggcg tcggggccgc actggttgca cacctcgccg
     3841 atgacctgat ggggcatcag ccgggtgggg tcggacacag ggtggtaatc ctgtgcctgc
     3901 cagctctgga tcatcgtcat ccattccggg tgcttggcgg gcttgatctg gggcagcatg
     3961 gcgttcagca cataggctgc atcgcccacg atggaaagat ccacgtccac gttcttgccc
     4021 agctcgctgg cgtcaatgtc gatctggatg atggtggcgt ttttggcaaa ggtcttgggg
     4081 ttcagcgcca cacggtcgga aaagcgggtg cccaccgcga tgagcacatc gcactctgcc
     4141 accgcccggt tggaggtgta gcagccgtgc atacccagca tgcccagatt catcgggtcg
     4201 ccatagggca caacgcctgc cgccatcagg gtgtaggtag cagggatctc cgccttgtgc
     4261 agcagatccc gcagcggctg gcagctggct gcgctgcgca cgccgccgcc aaagtacacc
     4321 agcggacgct gtgcggcgtt gatgaggtct gccgcccagt gcacctgctc ttcattatag
     4381 gtagttacgg tgcggatggg ctccggctgc ttgggggtga actcgcacac cgctgcagtc
     4441 acgtccttgg ggatatccac cagcaccggg cccttgcggc cgctctgcgc aatgcggaaa
     4501 gctgcccgca tggtgtcagc caagtcctct acccggcgca ccgtgaagtt atgctttgtg
     4561 atgggcaccg taatgccctc gatgtacgct tcctgaaagc cgtccttgcc gatgctgctg
     4621 gtgggcacgt tgccggtaaa ggccaccatg ggcaccgagt ccatataggc ggtggcaatg
     4681 ccggtgacca gat
//
