LOCUS       c00406_gnlPro..         2857 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JFIKLNHI_406.
ACCESSION   c00406_gnlPro..
VERSION     c00406_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 06:25:58
            Original ID  :: gnl|Prokka|JFIKLNHI_406
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 2857
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..2857
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:2857]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..2857
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..2857
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..2857
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(2..193)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg406_1"
                     /sec_met_domain="ILVD_EDD (E-value: 8.2e-10, bitscore:
                     25.9, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSDNVTKGSERAPNRSLFYALGYTPEELERPLIGVVSAYSEIVP
                     GHMNLDKIAEAVKAGVQMA"
     CDS             complement(398..1417)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg406_2"
                     /sec_met_domain="IlvN (E-value: 2e-75, bitscore: 240.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 4.5e-67, bitscore: 213.0,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIKKYYDSDCNLGVLDGKTVAVIGFGSQGHAHSENLAESGVNVV
                     VGLRKGSAHWAKASEFAATHDNFKVMEVEEAAKAGDVVMMLVPDELCADIYNTQVAPYM
                     TEGKALAFAHGFNIHFKTITAPKNVDVIMIAPKGPGHIVRRLYTEGEGCPSLICVEQDY
                     TGKAKDIALAYASGIGAGRAGILQTTFKEETETDLFGEQAVLCGGVSELIHAGFDTLVE
                     AGYEPEMAYFETCHEMKLIVDLINEGGFSKMRYSISNTAEYGDYRTGKRLITEETRKEM
                     KKVLTEIQDGTFASEFLTEMSPKGGRKVHFLAERRMQAEHPIEKVGAELRSMMSWLKK"
     CDS             complement(1517..2080)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg406_3"
                     /sec_met_domain="ALS_ss_C (E-value: 5.1e-29, bitscore:
                     88.6, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESDQRRVISLLVDNQSGVLARVSSLFCRRGFNIDSLTVSATNDP
                     AVSRITVTITSDEKALQQLVLQTERLEVTRQVFVLDGEKSLERELLLLKVESDVHNRTE
                     LREIACIYKAKIIDLSPDSMVFELIGRPDKLDAFLKMFEGYNILEQCRTGVTALERGGM
                     HQHIQKPPQEVRSVQLPPPGARRA"
     CDS             complement(2096..2857)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg406_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.3e-52, bitscore:
                     165.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="ASELGKNVDVDLSIVGDAAYVLNAMLPQIKPAKHPDWMTMIQSWQ
                     AQDYHPVSDPTRLMPHQVIGEVCNQCGPDAVYVTDVGQHQMWAAQYLRHTKSRGFITSG
                     GLGTMGFGYGAAIGAQMALGRQQRVVMFTGDASFHMNLNEACTAVSYELPIITVIFNNS
                     VLGMVRQWQTNFYGKRYSQTDPHRKTDFVKLADGFGLKGYRCTNLPEFQEAFADALQQK
                     GPTWIECIIDKDEKVLPMIPGGGDINDIIME"
ORIGIN
        1 cggccatctg cacaccggcc ttgacggcct cggcgatctt atccagattc atgtggccgg
       61 gcacgatctc gctgtaagcg ctgaccacgc cgatcagcgg gcgctccagc tcctcggggg
      121 tgtaacccag tgcgtagaat aagcttcggt tgggggcccg ctccgagccc ttggtcacgt
      181 tatcgcttct catggtttat tcctcttttc cttatagcaa aagaccccct cccaaaggag
      241 ggagcctttc ttagttttaa aagcagcttt tggctgaact ccttccgtca tcgcttgcgc
      301 gatgccacct ccctcacgga gggaggcttc acgctgcggt cagacaaaag gctccctctt
      361 tgagggggct gtcgccgcag gcgactgggg gagttaatta cttcttcagc cagctcatca
      421 tgctgcgcag ctctgcgccc accttctcga tggggtgttc ggcctgcatc cggcgctcag
      481 ccaggaagtg gaccttgcgg ccgcccttgg ggctcatctc ggtcaggaac tcggaagcaa
      541 aggtgccgtc ctggatctcg gtcaggacct tcttcatctc cttgcgggtc tcctcggtga
      601 tcaggcgctt gccggtgcgg tagtcgccgt actcggcagt gttggagatg gagtagcgca
      661 tcttggagaa gccgccctcg ttgatcaggt caacgatcag cttcatctcg tggcaggtct
      721 caaagtaggc catctcgggc tcgtaaccgg cctccaccag cgtatcgaaa ccggcgtgga
      781 tcagctcgga aacaccaccg cacagcacgg cctgctcgcc gaacagatcg gtctcggtct
      841 cctccttgaa ggtggtctgc aggatgcctg cacggcctgc gccgatgccg gaagcataag
      901 ccagtgcgat atccttggcc ttaccggtgt agtcctgctc cacgcagatc agagaggggc
      961 agccctcgcc ctcggtgtac aggcggcgca cgatgtggcc ggggcccttg ggagcgatca
     1021 tgatgacgtc cacattcttg ggggcggtga tggtcttgaa gtggatgttg aagccgtgtg
     1081 caaaggccag tgccttgccc tcggtcatgt agggagcaac ctgggtgttg tagatatcgg
     1141 cgcacagctc atcgggcacc agcatcatga caacatcgcc ggccttggca gcctcttcca
     1201 cctccatgac cttgaagttg tcatgggtgg cagcgaactc agaagccttt gcccagtggg
     1261 cagagccctt gcgcaggccg actacaacgt tgacgccgct ctcggccaga ttctcagagt
     1321 gtgcatgacc ctggctgccg aagccgatga cagcgacggt cttgccgtcc agcacgccga
     1381 ggttgcagtc ggaatcgtag tatttcttga tagccataat cgttagtctc cttttatctt
     1441 ttctggttgg tttatcttcc ggtcttgtat gctctgttct atctttcgct caccctgagc
     1501 ggaaaagcaa tgtgatttat gcccgtcttg cgcccggcgg gggcagctgg acggagcgca
     1561 cctcctgcgg cggcttctgg atatgctggt gcatcccgcc gcgctccagt gcggtaacgc
     1621 cggtgcggca ctgctcaagg atgttgtagc cctcgaacat tttcaggaaa gcgtccagct
     1681 tgtccggccg gccgatgagt tcaaagacca tgctgtccgg ggaaagatcg atgatctttg
     1741 ccttgtagat gcaggcgatc tcccgcagct ctgtgcggtt gtgcacgtcc gattccacct
     1801 tgagcagcag cagctcccgc tccagcgatt tttcgccgtc cagcacgaac acctgccggg
     1861 tgacttccag ccgctcggtc tgcaatacca gctgctgcaa ggccttttca tcgctggtaa
     1921 tggtcaccgt gatgcggctg actgccgggt cgttggtggc ggacaccgta aggctgtcga
     1981 tattgaagcc gcggcggcag aacaggctgg acacccgggc cagaacgccg ctctggttgt
     2041 ccaccagcag gctgatgacc ctgcgctgat cagattccat gatgctgtgt cctccttatt
     2101 ccatgatgat gtcgttgata tcgccgccgc cggggatcat gggcagcacc ttttcgtcct
     2161 tgtcgatgat gcactcgatc caagtggggc ctttctgctg caaggcatct gcaaaggctt
     2221 cctgaaactc cggcagattg gtgcagcggt agcccttcag gccaaagccg tctgccagct
     2281 tgacaaaatc ggtcttgcgg tgggggtcgg tctggctgta acgcttgccg taaaagttgg
     2341 tctgccactg gcgtaccatg cccagcaccg agttgttaaa gatgaccgtg atgatgggca
     2401 gctcgtagct gacggcggtg caggcttcgt tcaggttcat gtggaaggag gcgtcaccgg
     2461 taaacatcac cacacgctgc tggcgtccca gtgccatctg ggcaccaatg gcggcaccgt
     2521 agccaaagcc catggtgcca aggccgccgc tggtgataaa gccgcggctc ttggtgtggc
     2581 gcaggtactg cgccgcccac atctggtgct gacccacgtc ggtaacatac acggcgtcgg
     2641 ggccgcactg gttgcacacc tcgccgatga cctgatgggg catcagccgg gtggggtcgg
     2701 acacagggtg gtaatcctgt gcctgccagc tctggatcat cgtcatccag tccgggtgct
     2761 tggcgggctt gatctggggc agcatggcgt tcagcacata ggctgcatcg cccacgatgg
     2821 aaagatccac gtccacgttc ttgcccagct cgctggc
//
