LOCUS       c00255_gnlPro..        16616 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GPHLAPMJ_255.
ACCESSION   c00255_gnlPro..
VERSION     c00255_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 07:09:46
            Original ID  :: gnl|Prokka|GPHLAPMJ_255
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 52606
            Orig. end    :: 69222
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16616
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[62606:65598]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12992
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16616
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16616
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="2"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(488..1696)
                     /locus_tag="ctg255_53"
                     /transl_table=11
                     /translation="METQQRSTEYNFQGIMYFFRREKIQCRYQFSLRDAVDITLLQRAL
                     TAALASAPYYTQRLVQEKREMWLEPNTEPCLVYPGSTMRNIPEQTNGYLFCVSCEGDTV
                     YFDWHHFLLDGHGVSPLLTSILEQYCNLRYGTAFAVPQIVCDPPYDMEAMLAEYPPVEY
                     GSDVIQRDVVQTYEGALRRTRVCLSKQSLVEKALANNAKPVSALMGLLCMAMREYLGKE
                     KIRYSYSSDTRDVAGVPNALYNCVCSFGHTVQLQAQTRLADFVADVDADIRRDLQPESK
                     RHRMADQMGWVYKVNQQKAPLRIKQRVFQMGEYIGGTISDFWLSYLGNPLMPATPELAQ
                     YTTDFGVWVPPDGASVGVEAASLNGKIILCIHNKAPNPGLADILRKTFENEGVAVLEAE
                     DLD"
     CDS             complement(1703..1945)
                     /locus_tag="ctg255_54"
                     /transl_table=11
                     /translation="MERAEIISQITAILEDVAEVSPEDVTESSVLMDDLDLSSMEILTI
                     VADLEETFGLRIPEKELRNFVTMGDLVDYLAANVG"
     CDS             complement(1973..3442)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 214.2; E-value:
                     8.2e-66)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg255_55"
                     /sec_met_domain="AMP-binding (E-value: 8.5e-66, bitscore:
                     214.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKVLDNVYDLVTLNMEQRFSERVALRFYDKETDEVTAVHYKDYA
                     RDIRRAVNYFQSTIPDIKGKKICLLNKNSYEYAVNTFGIILAGGVLVLLNQHKSWDELS
                     YELGLVDPAAILTDGDDYGTKEQLQAAYGSILRPMDGFRAYEPVAEMPRCIGHDDLMIL
                     MFTSGTTGRSKGVMLSERNFFSVMRAHVQIGERMMEYKHDPELVVSQYTVLPMFHLGAF
                     ICLFSWAHGGWALNISGDIRNFYKEIRRMPSQVMAVVPVIMNSLHKDVMRGRKERLGEL
                     WVPICSSAMFDPQVMLDMATNGMFVVQTYGATETCGDGIINYAQDAKHIGAVGQGNDYL
                     DYKIEPDGELCIRGDSIMLGYYKDPEATAAVIDKDGWFHTGDLARVDEDGYYYITGRKK
                     NLIILDSGENVSPEELEGMLEKCPAVQECIVKELGKKIGVVVYCEKEHQQTVRDFIAQM
                     NRTVPLYKRIGVVEFSETPLPRNGAGKLVRK"
     CDS             3819..4934
                     /locus_tag="ctg255_56"
                     /transl_table=11
                     /translation="METTKPRTVNSIGMFDMLKGAGMLAIVLGHTAELYPLQLEGGLSL
                     TAFVGFIYRETLMAAFFIASGYGFRKRSISKCIHQQLKSLLKPFCYTAVFTTVLHFIIH
                     YKTFHYLPGSMTESIKVAGGFLLGLPHTATYFGQEFFSCGPMWYLLALLMGWILLDVIL
                     NIFPERYIPWAVGGAALLGWGASLVWELPFCLIQGAVITPYLYLGYLAKRQHWLDQPLS
                     RRMSCILWAAVLLIPAAALATRRTDCVSMAEWSLGPISILLDGLAGLLFIRLFLRWSQR
                     RNPLVRFFEAIGRRSLYIFCVHTVELIAIPWYLFAAKYADRPVLGISLQYILSLGSIWL
                     ICALLQRRRDLIIKLFPARRRTPQVHYAPRH"
     CDS             5001..5795
                     /locus_tag="ctg255_57"
                     /transl_table=11
                     /translation="MNHDAPMTPAAMQAHIAELEQQLKLSDEGVSQLAQRCLELEQQLL
                     ACQTELAKHSAEAENITLTLPQLFYDTGSGFSPRECLTATEDVYNELTHEVSVTFVLPE
                     DARAIRLDPGELACCITDLAISDERISFQSVNGLLLQEDSLLFLDVDPNLSLHCTTGFG
                     AGMKFAVNYHYYPLGRFLHEQPGKSLLRALNDLKLENAAAAQEAEEVLQASRAECMRLN
                     QQLLTLQGIQHEYQVSLETMRASSSWRLTAPLRRLLNLVRGH"
     CDS             5830..7437
                     /locus_tag="ctg255_58"
                     /transl_table=11
                     /translation="MYTSYSTLQRKQLSKQVYTDTQSTYLLVYAPGRHKALQAALQNQL
                     HRKFRLVTQLEDELTPDVAGVLLVSEDVECTPTALTYFAAALREGADLAVCDASFGFDG
                     STALYLSTRHLPGSSCALVSRALLDKVRAAARGKDSVTELLRLAHAMAQHSRCIPQALL
                     HFRRELCADDVFSAKGRRALILSHELTMTGAPIVLVSAVPVLRSLGFEVVVLGPSDEGS
                     LPLFLDAGAAVVTRPDCVTSSALWGLATSADFVLANTVVEAPVVNTLNGSFVPVLWWLH
                     DAFAGYPFISHSIPKALGKNVHLCAVGSHATAAMHSVRPDFAIEQLIYGLPDYAAEQFP
                     RYDISFAGGRPLFVTVGSLEHRKGPDIFCNAIRLLPSAVREKAAFLFVGKAADKGMYNA
                     VDSLVRDYPQTVFYRKRLERPEVKSLMEQCSCVVCASRDDPMPTFVTEGLIFGKPSIVS
                     EHTGTAGLVTEGVDGFLYKDDDPQQLADKLAWAIEHPEALAAMHGSCRCLYEQQFSNES
                     YVATLTRLVKELTDGEES"
     CDS             7616..8653
                     /locus_tag="ctg255_59"
                     /transl_table=11
                     /translation="MSQAAAQQPSRKKAVISLLVLLALTCIIVFTFKDHWAEITAALAQ
                     LSVWQVLAVLAVGLSYPLLEGCVAWVIVRSRLPQFTLRQGLDVGWCGTFGNVVTLGAGA
                     VPVQLYYLHKAGLPLGPGAGLMTLEYVFHKSTVLLYATVMLLLQHRWLAANTTGVMRYL
                     PMAYAVVAVIIVALVLLCVSPLVQNLARWLLGFLPKTEKWQQRRADWLEQLEVLGTESR
                     RLLTDKPRCLKIFALQALKLFGLFCLPYLCIRFMGLSPLGFWQVQLLTSLMLFVSNALP
                     NVAGMGSIETAFLLVFGSFLERGEVMSVLMLYRIASYYVVFAASAVGFFIAQRHLAQME
                     PPKEG"
     CDS             8658..9113
                     /locus_tag="ctg255_60"
                     /transl_table=11
                     /translation="MKSFHIPRTALFFILFALAAFAVLYRPVNVTSLIRASSQCTIRTE
                     VLTSPGHMSGTELSVLSMDDEKYQQVTEVLSTISCRKKLNQLYSSYRHDYPTQSVTASF
                     YDDAENHKMLITVYSDGVCILNNAFVSVKYPGGGAAQLYEQLAGLGK"
     CDS             10001..12253
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg255_61"
                     /sec_met_domain="Gly_radical (E-value: 2e-40, bitscore:
                     129.7, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 2.1e-267, bitscore:
                     880.3, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQFEQWEGFEGRIWKEEVNVRDFIQKNYTPYDGDESFLAGPTEA
                     TDKLWGALQQLQKAERAKGGVLDMETEVVSSLTSYGPGYIDENLKDLEQIVGLQTDKPL
                     KRAFMPYGGIKMAEQACTTYGYQPSAELHKIFTDYTRTHNQAVFDAYTPEMKKARHTHI
                     ITGLPDTYGRGRIVGDYRRVALYGIDALIKFKQEDLANCGDGTMTDDVIRLREEIARQI
                     SALKGMKKMAEAYGYDISQPAKDAKEACQWLYFGYLAAIKTQNGAAMSVGRISTFLDIY
                     IQRDLDKGILTESQAQELIDHMVMKFRMVKFARIPSYNQLFSGDPVWATLEVGGIGMDG
                     RSMVTKNCYRFLHTLENMGPAPEPNLTVLYSSALPEAFKKYAAKVSVNTSSVQYENDDV
                     MKPVWGDDYSICCCVSATQTGKEMQFFGARANLAKCLLYAINGGVDEKSHEQCGPNYAP
                     ITSEYLNYDEVLPKYVQMLDWLAGLYVNVLNLIQYMHDKYYYEEAEMALIDTDVRRTFA
                     TGIAGFSHVIDSLSAIKYAKVKVVRDENGLATGFETEGDFPKYGNDDDRADEIGVWLLK
                     TFLEMIKKRHTYRNSEATTSILTITSNVVYGKYTGALPDGRAAFTPFAPGATPSYGAEQ
                     NGLLASLNSVAKLPYHWALDGISNTQTINPEALGHSEGERVENLVQVLDGYFDQGAHHL
                     NVNVFGKEKLLDAMEHPEKEEYANFTIRVSGYAVKFIDLTREQQMDVMSRTCHAAL"
     CDS             12240..12992
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 63.8;
                     E-value: 6.5e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg255_62"
                     /sec_met_domain="Radical_SAM (E-value: 2.7e-29, bitscore:
                     94.7, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQPCNPIGYVHSLESFGSVDGPGVRFVVFLQGCALRCKYCHNPET
                     WAEGGEEWTAEALFQRVYRYRNYWGKKGGITVSGGEPLRQMDFLTEFFTLARAKGVHTA
                     LDTAGQPFRPDDPAYLAAFDRLMANTSLVILDLKEIDPERHRQLTGKDNANILAMARHI
                     SDLGIPLWVRHVLVPGLTDDEEGLRKTADFIRSLKTVQRVEVLPYHTLGLFKWQKLGIP
                     YPLPDAVPPTAEQVKRAEELLEVSRYPG"
     CDS             13564..14961
                     /locus_tag="ctg255_63"
                     /transl_table=11
                     /translation="MQIFNTLTRQKEEFVPQVPGEYRIYVCGPTVYNYIHIGNARPLIV
                     FDTLRRYLEYRGNKVIYVSNITDIDDKLIKKGQEEGTSMKEVAQRFEAEYLKDAAGLNC
                     EKPTVQPRATEHIPQILDIVKDLIDSGHAYVAKNGDVYFRVKSDPGYGKLSHLNLDDLE
                     SGNRELRSRMEDDLKEDPADFAVWKAAKPGEPAWESPYGMGRPGWHIECSAMSRTHLGK
                     TIDLHCGGQDLIFPHHENEIAQSECANGCEFARYWMHNGFINVDNQKMSKSLHNFFTVR
                     DVANLYGYEPIRYFMLTAGYRMPLNYTVDLIESCKNSLERLYTCRENLDFALSKTDFGT
                     DETLKEKAAEARTKFCTAMDDDLNTPDALASVFDLVKEINTLSATSSKAALETAAAAFD
                     EITGVLGLLYNRKKDEVPAEVTALVEKRAAAKKAKDWATADAIRAQLTELGWAVKDTAQ
                     GPQLSKL"
     CDS             complement(15121..16338)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035:Iron-containing alcohol dehydrogenase (Score:
                     335.1; E-value: 1.4e-102)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg255_64"
                     /sec_met_domain="Fe-ADH (E-value: 1.4e-102, bitscore:
                     335.1, seeds: 219, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARFTLPRDLYHGKGALEALKSFTGKKAMICVGGGSMKRFGFLDR
                     AVEYLKEAGMEVELFEGIEPDPSVETVMRGAEAMLKFEPDWIIAMGGGSPIDAAKAMWI
                     KYEYPEITFEEMCKVFGIPPLRRKAHFCAISSTSGTATEVTAFSIITDYQKGIKYPIAD
                     FEITPDVAIVDPDLAETMPKKLVAHTGMDAMTHAVEAYVSTAHCDYTDPLAIFAIRMIQ
                     GDLVDSYNGDMSKRDSMHNAQCLAGMAFSNALLGIVHSMAHKTGAAFADYGAHIIHGAA
                     NAMYLPKVIAFNAKDPEAKKRYGVIADEMKLGGANDDEKVKLLIEYLRGMNDALNIPHC
                     IQHYGPDSYPTEQGFVPENVFLERLPEIAKNAIADACTGSNPRQPSQEEMEKLLKCCYY
                     DTEVDF"
ORIGIN
        1 aggtattgat gacgctgccc ttggcgatgc ccaccacaaa aaaggccgct gccagcagcg
       61 ccactgcgcc agtcagcccc atgacggcgt agcccgccgc atagccgatg gtcagcagca
      121 gcacactgcg tttcatgccc agcgcactgg gcagcatgcc catcagcagc cctgccagca
      181 ggttgcccac gctcatcagg gagagcagtg taccggtcat gccgtaggca aagccgtagc
      241 gctcctgcag cagactgacc accacacctg cgctgatggc acagatgccg ctgaagaaaa
      301 aggtcgcaaa gcccgcattg cgcaggcgcg tgttctgttg ttccatggtg ttcctctcct
      361 tgcggaaata tcctttctct atttaaccat tttttcgcat ctttgcaacc ggattttctt
      421 acaaaaagca gcaaaaaaac tgccgcacaa aacgtgcagc agttttttct tttataataa
      481 gtatttctca gtccagatct tcggcttcca gcaccgcaac gccttcgttt tcaaaggtct
      541 tgcggaggat atcagccaga cccgggttgg gtgccttgtt gtggatgcac aggatgatct
      601 ttccgttcag gctggcagcc tccacgccca cggatgcacc gtccggcggt acccagacgc
      661 caaaatccgt ggtgtactgc gccagctccg gggtggcagg catgagcgga ttgcccagat
      721 agctgagcca gaaatccgaa atcgtgccgc cgatgtactc gcccatctgg aacacccgct
      781 gcttgatgcg caggggtgcc ttttgctggt tcaccttgta cacccagccc atctggtcgg
      841 ccatacggtg acgcttggac tccggctgca ggtcccgcct gatgtctgca tctacatcag
      901 ccacaaaatc tgccaggcgg gtctgggctt gcagctgcac cgtatgccca aagctgcata
      961 cgcagttgta cagcgcattc ggcacaccgg ccacatcgcg ggtatcagac gagtaggaat
     1021 accggatctt ctccttgccc agatactccc gcatggccat acacagcaga cccatcagag
     1081 cgcttaccgg ctttgcgttg ttcgccagcg ctttttccac aaggctctgc ttgctcaggc
     1141 acacccgggt gcggcgcagc gcaccctcgt aggtctgcac cacatcccgc tggatgacat
     1201 cgctcccgta ctccacaggc gggtactctg ccagcatggc ctccatatca tagggcgggt
     1261 cgcacacgat ctgcggcacc gcaaaggccg tgccgtagcg caggttgcag tactgctcca
     1321 gaatgctggt gagcaggggc gataccccgt ggccgtccag caggaagtga tgccagtcaa
     1381 agtagacggt atccccttcg cagctgacgc agaacaggta gccgttcgtc tgttccggga
     1441 tattgcgcat ggtgctgccg gggtacacaa ggcagggctc cgtattgggc tccagccaca
     1501 tctcccgctt ttcctgcacc agacgctggg tataataggg cgcacttgcc aaggccgctg
     1561 tcagtgcccg ctgcaaaagg gtgatatcca ccgcatcccg cagcgagaac tggtaccggc
     1621 actggatctt ttcccgacgg aaaaagtaca tgattccctg aaagttatat tccgtcgagc
     1681 gctgctgtgt ttccattggt ttttacccca cgtttgctgc cagataatcc accagatcac
     1741 ccatggtgac aaagttgcgc agctcctttt ccgggatgcg cagaccaaag gtctcttcaa
     1801 gatctgccac aatggtcagg atctccatag aggacagatc cagatcgtcc atcaggacgc
     1861 tgctttcggt cacatcctcc ggcgatacct ctgcgacatc ctccagaata gccgtgatct
     1921 gagaaatgat ttctgcacgt tccatcgtat tatgcttcct ttctgttgcg ttttacttgc
     1981 gcaccagctt gcctgcgccg ttgcggggca gcggcgtttc gctgaattcc accacgccaa
     2041 tgcgcttgta cagcgggaca gtgcggttca tctgggcaat aaagtcccgc accgtctgct
     2101 ggtgctcctt ttcacagtat accacaacac ctatcttttt gcccagttct tttacgatac
     2161 attcctgtac ggcgggacat ttttctaaca tgccctccag ctcttcgggg ctgacgttct
     2221 cgccgctgtc cagaatgatc aggttcttct tgcggccggt gatgtagtag tagccgtcct
     2281 cgtccacccg ggcaaggtcg ccggtgtgga accagccgtc cttgtcgatg accgcagcgg
     2341 tggcctcggg gtccttgtag tagcccagca tgatgctgtc gccccggatg cacagctctc
     2401 cgtccggctc gatcttgtag tccagataat cgttgccctg tcccacagcg ccgatgtgct
     2461 ttgcatcctg cgcgtagttg atgatgccgt cgccgcaggt ctcggtagcg ccgtaggtct
     2521 gcaccacgaa catcccgttg gtggccatat ccagcatcac ctgcgggtca aacatggcag
     2581 aggagcagat gggcacccac agctcgccca agcgctcctt gcggccgcgc atcacgtcct
     2641 tgtgcaggga gttcatgatc accggcacca ccgccatgac ctgactgggc atccgccgga
     2701 tctccttata gaaattgcgg atatcgccgc tgatgttcag cgcccagccc ccgtgtgccc
     2761 aagagaacag gcagatgaat gcacccagat ggaacatggg cagcaccgtg tactggctga
     2821 ccacaagctc cgggtcgtgc ttatactcca tcatgcgctc accgatctgc acatgggcgc
     2881 gcatcacgct gaagaagtta cgctcgctca gcatcacgcc cttgctgcgg ccggtggtgc
     2941 cggaggtgaa catcaggatc atcaggtcat cgtggccgat gcagcggggc atctctgcca
     3001 ccggctcata agcgcggaag ccgtccatcg ggcgcaggat gctgccgtag gcggcctgca
     3061 gctgctcttt tgtgccgtag tcgtcgccgt cggtcaggat ggcagcgggg tccaccagcc
     3121 ccagctcgta ggacagctcg tcccagctct tgtgctggtt gagcagtacc agcacgccgc
     3181 ccgccagaat gatgccgaag gtgttcacgg catattcgta gctgttttta ttcagcaggc
     3241 agatcttttt gcccttgata tccgggatgg tgctctggaa gtagttgacc gcacggcgga
     3301 tgtcccgcgc gtagtcctta taatggactg cggtcacctc gtccgtttcc ttatcataaa
     3361 agcggagcgc cacacgctcc gaaaaacgct gttccatatt cagggtgacc agatcataca
     3421 cgttgtccaa taccttgatc attgtatttt cctcctgcgt tgttatttca tcctgcggca
     3481 gtgtgctgca ctgtgctcag tatacaatat tttccaatgc aatgcaatac ttctgcaaca
     3541 tttaatttct cactttgaca actttcaatt gcacatcttg ggatacgccc cggccaaatt
     3601 ctacctttcg ttgcaatccg ccggttttcg tgctacaatt tttagcgcaa aataccagtt
     3661 ccggtatggt gcagactgca aaacaaaatt gacagtctct ataaaaagca ttatactagc
     3721 catatatcat ggcaatgctg tataaaaact gatcatttgc gccgtatccg gcttttttct
     3781 cgagggggta ttggcccggc gcagggaagg aatctttcat ggaaacaacc aagccccgca
     3841 ctgtcaactc catcgggatg tttgatatgc tcaagggcgc tgggatgctg gccatcgtgc
     3901 tgggacacac tgcggagctt tacccactcc agctggaggg cggcctgtcg ctgacggcct
     3961 ttgtcggctt tatctaccgc gaaacgctga tggcggcctt ttttattgcc agcggctacg
     4021 gcttccgcaa gcgctccatc agcaagtgca tccaccagca gctcaaaagc ctgctcaagc
     4081 ccttttgcta cactgcggtg ttcaccacgg tgctgcactt catcattcat tataaaacct
     4141 ttcactatct gcccggctcc atgactgaga gcatcaaggt ggcgggcggc tttctgctgg
     4201 gtctgcccca cactgccacc tacttcgggc aggagttctt ttcctgcggg cccatgtggt
     4261 atctgctggc gctgttgatg ggctggatct tactggacgt tatcctgaac atcttcccgg
     4321 agcggtacat cccttgggcg gtgggcggtg ccgccctgct gggctggggt gccagccttg
     4381 tatgggagct gcccttctgc ctgatccagg gcgcggtgat cacgccatac ctgtaccttg
     4441 gctaccttgc caaacggcag cattggctgg atcagccttt gtcccgccgg atgtcctgca
     4501 tcctgtgggc agccgtactg ctgatcccgg cagccgccct tgccacccgc cgcaccgact
     4561 gtgtatccat ggccgagtgg tcgctgggcc ccatcagcat cctgctggac ggccttgccg
     4621 gtctgctgtt tatccggctg tttttgcgct ggagccagcg ccgcaacccg ctggtgcgct
     4681 ttttcgaggc catcggccgc cgttctctgt acatcttctg cgtacatacg gtggagctga
     4741 tcgccattcc gtggtatctg ttcgccgcca aatacgccga ccgccctgtt ttgggcatca
     4801 gcctgcaata catcctttcg ctgggctcca tctggctgat ctgtgccctg ctgcagcggc
     4861 ggcgggatct gatcatcaag ttgttccccg cccggcggcg cacccctcag gtacattacg
     4921 ccccgcggca ctgatttttc tgaatgtttt ggctgcggcg gtgcagctgt tataggataa
     4981 aggaagagga ggatcccgtt atgaaccacg atgcccccat gacccctgct gccatgcagg
     5041 cgcacattgc cgagctggag cagcagctca agctttcgga cgagggtgtt tcccagctgg
     5101 cgcagcggtg tctggagctg gagcagcagc tgctggcttg ccagaccgag cttgccaagc
     5161 acagcgccga ggctgagaat atcaccctta ccctgccgca gctgttctac gacaccggca
     5221 gcggcttttc gccccgggaa tgcctgactg ccaccgagga tgtctacaac gaactgaccc
     5281 acgaggtctc ggtcaccttt gtcctgccgg aggacgcacg cgccatccgt ctggaccccg
     5341 gcgagttggc ctgctgcatc accgatcttg ccatctcgga cgagcgcatc agcttccagt
     5401 cggtcaacgg ccttctgctg caggaggaca gcctgctgtt tttggacgta gaccccaacc
     5461 tttcgctgca ctgcaccacc ggctttggtg ccggcatgaa gtttgcggtg aactatcact
     5521 actacccgct gggacgtttt ctgcacgagc agcccggcaa gtctctgctg cgggcgctga
     5581 acgacctgaa gcttgagaac gccgctgccg cgcaggaggc agaggaagta ttgcaggcca
     5641 gccgcgccga gtgtatgcgg ctgaaccagc agctgctgac cttgcagggc atccagcacg
     5701 aatatcaggt ttcgctggaa acgatgcgcg ccagcagcag ctggcggctg accgccccgc
     5761 tgcgcagact gctgaaccta gtgcgcggtc actgagcccg cccgatattc tgcccggagg
     5821 agttggatca tgtacaccag ttacagtacc ctgcagcgca agcaattgtc caagcaggtc
     5881 tataccgata cccagagcac ctatcttctg gtctatgcgc cggggcgtca caaggcgctg
     5941 caagcggcgc tgcaaaacca gctgcaccgc aagttccgtc tggtgaccca gcttgaggac
     6001 gagctgaccc ccgatgtagc cggggtgctg ctggtaagcg aggatgtgga gtgcaccccc
     6061 accgccctga cctattttgc cgccgccctg cgggagggcg cagaccttgc ggtctgcgac
     6121 gcctcctttg gctttgacgg ctctaccgcc ctgtacctga gcacccggca cctgcccggc
     6181 agcagctgcg cactggtgtc ccgcgcattg ctggacaagg tacgcgccgc cgcccggggc
     6241 aaggacagcg ttaccgaact gctgcgtctg gcccacgcca tggcgcagca cagccgctgc
     6301 atcccgcagg cgctgctgca cttccgccgg gagctgtgcg ccgacgatgt attctctgcc
     6361 aagggccgcc gtgcgctgat tttgagccat gagctgacca tgaccggtgc gcccatcgtg
     6421 ctggtaagtg ccgtgccggt gctgcgcagc ttaggctttg aggtggtggt gctggggccc
     6481 tcggatgaag gctcgctgcc gctgtttctg gacgccgggg ccgctgtggt cacccgcccg
     6541 gactgcgtta cttccagcgc cctgtggggg ctggccacca gcgcagactt tgtgctggcc
     6601 aacacggtgg tggaagcgcc ggtggtgaac accctgaacg gctcctttgt gccggtgctg
     6661 tggtggctgc acgatgcctt tgcgggctac cccttcatct cccacagcat ccccaaggcg
     6721 ctgggcaaaa acgtgcacct ctgcgccgta ggctcccacg ccaccgccgc catgcactcc
     6781 gtccggccgg attttgccat cgagcagctg atctacggtc tgccggacta tgcagccgag
     6841 caattccccc gctatgacat cagctttgcc ggggggcgtc ccctctttgt gacggtaggc
     6901 tcgctggaac accgcaaggg tccggacatc ttctgcaacg ccatccggct gctgccctct
     6961 gcagtgcggg aaaaagctgc cttccttttt gtgggcaaag ccgccgacaa ggggatgtac
     7021 aacgccgtgg acagcttggt gcgggactat ccccagaccg ttttctaccg caagcggctg
     7081 gagcgcccgg aggtcaaatc cttgatggag cagtgcagct gcgtggtgtg cgcctcccgg
     7141 gatgacccca tgcccacctt cgtcaccgag ggactgatct tcggcaagcc ctccatcgta
     7201 tcggagcaca ccggcaccgc cgggctggtg accgaaggcg tggacggctt cctctacaag
     7261 gacgacgacc cgcagcagct ggccgacaag ctggcctggg ccatcgaaca cccggaggcg
     7321 ctggccgcca tgcacggcag ctgccgctgc ctgtacgagc agcagttctc caacgaatcc
     7381 tatgtcgcca ccctgacaag gctggtaaaa gagctgacgg acggggaaga atcatgaaaa
     7441 aaacactgcc ggacagctgc acgctgcccg gcagtgcttt ttcacgggag aggtctcccc
     7501 attttatcaa atcccccaaa ttgcccaaca aagttccgcc tccgttcaca aagggcggcg
     7561 ggagatgtgc tatactggtt ccagaatttc cggttatgaa aggagttttg tttccatgag
     7621 ccaagccgcc gcgcagcagc cctcccgcaa aaaggccgtg atctctctgc tggtgctgct
     7681 ggcacttacc tgcatcattg tgttcacttt taaggatcac tgggccgaga tcactgcggc
     7741 gctggcgcag ctgtcggtgt ggcaggtgct ggcggtgctg gcggtcggcc tcagctaccc
     7801 cctgctggaa gggtgcgtgg cgtgggtcat cgtgcgcagc cgtctgccgc agttcaccct
     7861 gcggcagggg ctggatgttg gctggtgcgg cacctttggc aacgtggtca cgctgggtgc
     7921 cggtgcggtg ccggtgcagc tgtactacct gcacaaggcc gggctgccgc tgggccccgg
     7981 cgcagggctg atgacgctgg aatacgtttt ccacaagagc acggtgctct tgtacgccac
     8041 cgtgatgctg ctgttacagc accgctggct tgccgccaac accaccggtg tcatgcggta
     8101 tctgcccatg gcatacgctg tggtagcggt gattatcgtg gcgctggtgc tgctgtgcgt
     8161 ctcgccgctg gtgcagaacc tcgcccgctg gctgctgggc tttttgccca agaccgaaaa
     8221 gtggcagcag cgccgcgccg actggctgga gcagctggag gtgctgggca ccgagagccg
     8281 ccgcctgctg acagataagc cccgctgcct gaaaattttt gccctgcagg cactcaagct
     8341 gttcgggctg ttctgcctgc cctacctgtg catccggttc atggggcttt ccccgctggg
     8401 cttctggcag gtgcagctgc tcaccagcct gatgctcttc gtttccaacg ccctgcccaa
     8461 tgtagccggg atgggctcga ttgaaaccgc ctttctgctg gtgttcggca gctttctgga
     8521 acggggcgag gtaatgagcg tgctgatgct ctaccgcatc gccagctatt atgtggtatt
     8581 tgccgccagc gccgtgggct tcttcatcgc ccagcggcat ctggcccaaa tggagccgcc
     8641 aaaggagggg tgagcagatg aaaagcttcc acattccccg caccgcttta ttttttatcc
     8701 tgtttgcact ggcagctttt gcggtgctat accggcctgt caatgtcaca tctttgatcc
     8761 gtgccagttc tcagtgtacc atccgaacgg aagtcctgac ctctcccggt cacatgagcg
     8821 gcacagagct ttctgttctt tccatggacg atgaaaaata ccagcaggta acggaggtgc
     8881 tttccaccat ttcctgccgg aaaaaactca atcagcttta ttcttcttat cgccacgatt
     8941 accccacgca gtccgtcacg gccagctttt acgacgatgc cgaaaatcac aagatgctta
     9001 tcaccgtcta ttccgacggc gtgtgcatcc tgaacaacgc ctttgtcagc gtaaaatacc
     9061 ccggcggcgg cgcagcacag ctgtatgaac agctggcggg gctgggaaag taaaaacaat
     9121 tttgaatgcc ctccgcttgc gctctgggca tattcagcgg aaagaatatt ttttaatttg
     9181 cagttcggga aaatctgcgg attttcccga actgcctttt cacgggtggg gtcgtaaagg
     9241 cagatggcat atctgtcgtt tgccttgcat ccttctctgt gaaagctgga ttcagaaacg
     9301 cccgcaggcg tttctgaatc caaaatttaa aatgaaattc cttaaactat ggccaaagcg
     9361 cacgcggcgg ccatttcaaa tcgtccctca aggcctagcg cacagaggga gtttcctcac
     9421 aaaacaaaaa tcggggcact caggtggtca agctgagtgt cccgtttttg ttttctttgc
     9481 gtcggctgtg gtaccaaaca cagccggtgc cgcgccggaa gcagcagagc aaaccgtgct
     9541 gccgcttccc gtagaaaaga gaaaggaatg gaggaatgga gcggagcgct tgcagacgct
     9601 ccttttttct ggtgcaacgc ggttagaatt agctaaccac cgctgcgaga acaggatacc
     9661 acagtcagtt agtcttgtca acccttaatt tgcaaatttt ttcgcaaagt tgccgtgccg
     9721 ccggggtttc tgccgttttt ctacattctg cccaaagaat agcctttccg ctggaagaaa
     9781 acccacttgt tttctattgc tttttaaaac gattcttgct attataataa cgcaagattt
     9841 tgtgggcagg tttttatttt tgtctacacc ttgtagtaag ggctgccgca gacggcagcg
     9901 caagaccgtt tcgcccccag aaaaccgccc agacagagcg gtttttcaaa ggctcattag
     9961 ttagaaaacg ctaactgcgt aatggagcaa ggaggttcca atgatccagt ttgaacagtg
    10021 ggaaggcttt gaaggccgca tctggaagga agaggtcaac gtgcgtgact tcatccagaa
    10081 aaactacact ccctatgacg gcgacgaaag ctttctggca ggccccaccg aggctaccga
    10141 taagctttgg ggtgctttgc agcagctgca gaaagccgag cgtgccaagg gcggcgtgct
    10201 ggatatggag accgaggtgg tcagcagcct gacctcctac ggccccggct atattgacga
    10261 aaacctgaag gatctggagc agatcgttgg cttacagacc gacaagcccc tcaagcgcgc
    10321 ctttatgccc tacggcggca tcaagatggc agagcaggcc tgcaccacct acggctacca
    10381 gccctctgcc gagctgcaca agatctttac cgactacacc cgcacccaca atcaggccgt
    10441 gttcgatgcc tacaccccgg agatgaagaa ggcacgccac acccacatca tcaccggcct
    10501 gcccgacacc tacggccgcg gccgcatcgt gggcgactac cgccgcgtgg ccctgtacgg
    10561 cattgatgcc ctgatcaagt tcaagcagga ggaccttgcc aactgcggcg acggcaccat
    10621 gaccgatgac gtcatccgcc tgcgcgagga gatcgcccgc cagatcagcg ccctgaaggg
    10681 catgaagaag atggccgagg cctacggcta cgacatctcc cagcctgcca aggacgccaa
    10741 ggaggcctgc cagtggctgt acttcggcta tctggccgcc atcaagaccc agaacggcgc
    10801 cgccatgagc gtgggccgca tctccacctt ccttgacatt tatatccagc gcgatctgga
    10861 caagggcatc ctgaccgaaa gtcaggcaca ggagctcatc gaccacatgg tcatgaagtt
    10921 ccgcatggtc aagtttgccc gcatccccag ctacaaccag ctgttctccg gcgaccccgt
    10981 gtgggcgacg ctggaggtgg gcggcatcgg catggacggc cgcagcatgg tcaccaagaa
    11041 ctgctaccgc ttcctgcaca cgctggaaaa catgggcccc gcaccggagc ccaacctgac
    11101 cgtgctgtac tcctctgccc tgcccgaggc ctttaagaag tacgccgcca aggtgtccgt
    11161 caacaccagc agcgtccagt acgagaacga tgacgtgatg aagcccgtct ggggcgacga
    11221 ttactccatc tgctgctgcg tgtctgccac ccagaccggc aaggagatgc agttcttcgg
    11281 cgcacgcgcc aaccttgcca agtgcctgct gtacgccatc aacggcggcg tggacgagaa
    11341 gagccacgag cagtgcggcc ccaactacgc ccccatcacc agcgagtacc tgaactatga
    11401 cgaagttctg cccaagtacg tccagatgct ggactggctg gccgggctgt acgtcaacgt
    11461 gctgaacctc atccagtata tgcacgacaa gtactactac gaggaagccg agatggccct
    11521 gatcgacacc gatgtgcgcc gcacctttgc caccggcatt gcaggcttct cccacgtgat
    11581 cgactccctg agcgccatta agtacgccaa ggtgaaggtg gtgcgcgatg aaaacggcct
    11641 tgccaccggc tttgagaccg agggcgactt ccccaagtac ggcaacgacg atgaccgcgc
    11701 cgacgagatc ggcgtgtggc tgctcaagac cttccttgag atgatcaaga agcgccacac
    11761 ctaccgcaac tccgaggcta ccacctccat cctgaccatc acctccaacg tggtgtacgg
    11821 caagtacacc ggcgctctgc cggatggccg cgccgccttc accccgtttg cacccggcgc
    11881 tacccccagc tacggcgcag agcagaacgg cctgctggcc tcgctgaact ctgtggcaaa
    11941 gctgccctac cactgggcgc tggacggcat ctccaacacc cagaccatca accccgaggc
    12001 actgggtcac agcgagggcg agcgcgtgga gaatctggtg caggtgctgg acggctactt
    12061 cgatcagggc gcacaccacc tgaacgtgaa cgtctttggc aaggagaagc tgctggacgc
    12121 catggagcac cccgagaagg aagagtacgc caacttcacc atccgcgttt ccggctacgc
    12181 cgtcaagttc atcgacctga cccgcgagca gcagatggat gtcatgtccc gtacctgcca
    12241 tgcagccctg taaccccatc ggctatgtcc actcgctgga atccttcggc tcagtggacg
    12301 gccccggcgt gcgctttgtg gtgtttttgc aggggtgtgc cctgcggtgc aagtactgcc
    12361 acaaccccga aacatgggca gagggcggcg aggaatggac agcagaagcg ctgttccagc
    12421 gggtataccg ctaccgcaac tactggggca aaaagggcgg catcacggtc agcggcggcg
    12481 agccgctgcg gcagatggac tttctgaccg agttcttcac gctggcgcgt gccaagggcg
    12541 tgcacacggc gctggacact gccgggcagc ccttccgccc ggatgacccg gcctatctgg
    12601 cggcgttcga ccgcctgatg gctaacacca gtctggtgat tttagacctc aaggagatcg
    12661 acccggagcg ccaccggcag ctcaccggca aggacaacgc caacattctt gccatggcgc
    12721 ggcacatctc cgacctcggc atcccgctgt gggtgcggca cgtccttgtg cccgggctga
    12781 ccgacgacga ggaaggtctg cgcaaaacag cagacttcat ccgcagcctg aaaacggtac
    12841 agcgggtgga ggtgctgccc taccacacct tggggctgtt caagtggcaa aagctgggca
    12901 ttccctatcc tctgccggac gcagtaccgc ccacggcaga gcaggtaaag cgggcagaag
    12961 aactgctgga agtgagccgg tatcccgggt aaagcaccac cgttttgatt gcgctccgct
    13021 tcgctctgcg caatttcagc ggaaagaata tctatgattt tggcccccgg agcgtctgcg
    13081 gacgctccgg gggccctttt cacgggtaaa aataggatat cggaacgccc gcaggcgttc
    13141 cgatatcccg aaatttaaaa taattcttcc gctgaggatg cccaaagcaa cgcggagggc
    13201 attctgaatc gttctttgtt cctccttgac ttccctgcac cgcaccgcta taataaaggg
    13261 gtaaaaggat aaatgcgttt atccgggcag agtagcgccg cacaccgtct gcgcagagag
    13321 aacaggccac tggctggaag cctgtttgca gatcgctgcg caaagtgcgc ccggacagca
    13381 cgcggcggga accccgtggg gaagtatcgc cgtgcggtgc gccgccgtta ccggctttga
    13441 gcgacaaaca gaagtggaac cgcgattttg attttaaaac cgccttcgga gttgtgcctt
    13501 gtgcaccgct ccgggggcgt tttgttttgc ggcttctgtt tggaacaaaa aggagaattg
    13561 accatgcaga tcttcaacac cctgacccga cagaaggaag aatttgtgcc gcaggtgccc
    13621 ggcgagtacc gcatctacgt ctgcggccct accgtgtaca actatatcca catcggcaac
    13681 gcacgcccgt tgatcgtgtt cgacaccctg cgccgctatc tggaataccg gggcaacaag
    13741 gtgatctacg tttccaacat caccgatatc gacgataagc tcatcaaaaa gggacaggaa
    13801 gagggcacct ccatgaagga ggtagcgcag cgctttgagg ccgagtacct gaaggatgcc
    13861 gccgggctga actgcgaaaa gcccaccgtg cagccccgcg ctaccgagca tatcccccag
    13921 atcctcgata tcgtcaagga tctgatcgac tccggccacg cctacgttgc caagaacggc
    13981 gatgtgtact tccgggtgaa gagcgacccc ggctacggca agctgagcca cctgaatctg
    14041 gacgatctgg aaagcggcaa ccgcgagctg cgcagccgca tggaggacga tctgaaggaa
    14101 gatcccgccg actttgccgt ctggaaggct gcaaagcccg gtgagcccgc atgggaaagt
    14161 ccctacggca tgggccgccc gggctggcac attgagtgca gcgccatgag ccgcacccat
    14221 ctgggcaaga ccatcgacct gcactgcggc ggtcaggatc tgatcttccc ccaccacgaa
    14281 aacgagatcg cccagagcga gtgcgccaac ggctgcgagt ttgcccgcta ctggatgcac
    14341 aacggtttca tcaacgtgga caatcagaag atgtccaaga gcctgcacaa cttctttacc
    14401 gtgcgggatg tggcaaacct ctatggctac gagcccatcc gctacttcat gctgaccgcc
    14461 ggctaccgca tgcccctgaa ctacaccgta gacctcatcg agagctgcaa gaacagtctg
    14521 gagcgcctgt acacctgccg cgagaatctg gactttgccc tgagcaagac cgacttcggc
    14581 accgatgaga ctttgaagga aaaggccgcc gaggcacgca ccaagttctg caccgccatg
    14641 gacgatgacc tgaacacccc ggatgcactg gcctccgtgt tcgatctggt caaggagatc
    14701 aacaccctgt ctgcaacttc cagcaaggct gcactggaga ccgctgccgc cgcctttgac
    14761 gagatcaccg gtgtgctggg tctgctgtat aaccgcaaga aggacgaggt gcccgccgag
    14821 gtgaccgcgc tggtagagaa gcgcgctgcc gccaaaaagg ccaaggactg ggccaccgct
    14881 gatgccatcc gcgcacagct gaccgaactg ggctgggctg ttaaggacac tgcacagggt
    14941 ccccagctga gcaagctgta acgccttagt agtatgaaag gggttcggaa acgccgtagg
    15001 cgtttccgaa cccctttttt cacgggagaa tgcaggcaaa accggcaaaa gccccgcagg
    15061 gcggtatgct ctgcggggct tttgtccata aggaaggagg tgtaataaag aaaggacgga
    15121 tcagaaatcc acctcagtgt cgtagtagca gcacttgagc agcttctcca tctcctcctg
    15181 actgggctgg cgggggttgg agccggtgca ggcgtcggcg atggcgttct tggcgatctc
    15241 gggcagacgc tccaggaaca cattctccgg cacaaagccc tgctcagtgg ggtaggagtc
    15301 cgggccgtag tgctggatgc aatgggggat gttcagggcg tcgttcatgc cgcgcaggta
    15361 ctcgatgagc agcttgacct tttcgtcatc gtttgcgccg cccagcttca tctcgtctgc
    15421 gatgacgccg tagcgcttct tggcctcggg gtccttggcg ttgaaggcga tgaccttggg
    15481 caggtacatg gcgttggcag cgccgtggat gatgtgtgcg ccgtagtctg caaaggcagc
    15541 gccggtcttg tgtgccatgg agtgcacgat gcccaacagt gcgttggaga aagccatacc
    15601 ggcaaggcac tgggcgttgt gcatggagtc gcgcttggac atatcgccat tgtagctgtc
    15661 cactagatcg ccctggatca tgcggatggc gaagatggcc agaggatcgg tgtagtcgca
    15721 gtgtgcggtg gaaacataag cctccacagc gtgagtcatg gcgtccatac cggtgtgggc
    15781 aaccagcttc ttgggcatgg tctcagccag atcggggtcc acgatggcca cgtccggggt
    15841 gatctcaaag tctgcgatgg ggtacttgat gcccttctgg tagtcggtga taatggagaa
    15901 agcggtcacc tcggtggcag tgccggaggt ggaggaaatg gcgcagaagt gtgccttgcg
    15961 gcgcagcggc gggatgccga acaccttgca catctcctca aaggtgatct cggggtactc
    16021 gtacttgatc cacatggcct tggctgcatc gatgggagag ccgccgccca tggcaatgat
    16081 ccagtcgggc tcaaacttca gcatagcctc ggcaccgcgc atgacggtct ccacggaagg
    16141 atcgggttcg atgccctcga acagctccac ttccatgccg gcttccttca ggtactccac
    16201 ggcacgatcc aggaagccga aacgcttcat ggagccgccg ccgacgcaga tcattgcctt
    16261 ttttccggtg aaggacttca gcgcttccag agcgcccttg ccatggtaca gatcacgggg
    16321 cagagtaaaa cgagccataa tacaaaacct ccaaaaatag tacggcacac gcagcgctgt
    16381 gccatatttc attattatgt taattatata acaatttgga ggcagcttca attgacgtac
    16441 cgggagaaaa agtcgttcta ttttgggcgg tttccacaag cagtaggatg caacaagccc
    16501 cctgccctga aaaagcgcaa aaaaacaccc cgaagtccta agacttcgag gtgtttgcct
    16561 ttggagctgc tatccagatt cgaactggag acctcatcct taccaaggat gcgctc
//
