LOCUS       c00037_gnlPro..        13720 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KDKLKNFL_37.
ACCESSION   c00037_gnlPro..
VERSION     c00037_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 11:19:32
            Original ID  :: gnl|Prokka|KDKLKNFL_37
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13720
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..234
                     /locus_tag="ctg37_1"
                     /transl_table=11
                     /translation="PSLSDGACLGFVRHFQVRSPGLLGTFRCNIYFLRCATMRKQLSDI
                     LFLVQGNLIMKKTPDSRCRREFLQSVLRRNLL"
     protocluster    1..13720
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[230:3720]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      231..3720
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13720
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13720
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(231..998)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.5; E-value: 8.6)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg37_2"
                     /sec_met_domain="Fer2_3 (E-value: 1.4e-23, bitscore: 74.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 4.7e-11, bitscore: 34.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.7e-06, bitscore: 19.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENREAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPERQVTTCQLHMRKFKDGDTVWIE
                     PFRAKAFPILRDLMVDRSALDRIIASGGYIDVRTGSAPNANNIAVEKVKADAAFDAAAC
                     IGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSKRVLAMMKQMEAEGFGNCTNQY
                     ECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(1039..2997)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg37_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.6e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 7.4e-38,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             complement(3019..3720)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg37_4"
                     /sec_met_domain="SucD_FumR (E-value: 1.6e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             3921..4193
                     /locus_tag="ctg37_5"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAATRAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             4226..5011
                     /locus_tag="ctg37_6"
                     /transl_table=11
                     /translation="MVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSADGFRDYFVQLT
                     ECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLGIGEIGLNRNT
                     SHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLDPCRVLVDHCE
                     EHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADWGDSDPLALTA
                     LACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(5045..5323)
                     /locus_tag="ctg37_7"
                     /transl_table=11
                     /translation="VGKWLSLNLYPPFPSMNLQKQQLLLRLFRYFKSRKGEPRFFNKRN
                     ICLLAAAGAYILTPDEFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(5710..6444)
                     /locus_tag="ctg37_8"
                     /transl_table=11
                     /translation="LHHFIKILTMNKLLSTLILSVGMSLSATAATSLLDSSIVGYSDFA
                     SQTADFGTLKDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPDAYTA
                     LFNAKNSSVSWGVGLNTDRKLQGLWNNTSYSGPVVDTPLGTEGSLTISVVTGDLGTRIY
                     FGDSTTYYSNSGLKFGNQQIDQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIP
                     EPATASLGLLGLAALMMRRRRA"
     CDS             6467..6688
                     /locus_tag="ctg37_9"
                     /transl_table=11
                     /translation="LNNEFGIRYDRFIRALMNHGRNDGFVPLPFTGCDSYNPIRIMFSI
                     SWFPFYSRSSSSFPLHAETVLQHYYPGL"
     CDS             6648..7277
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg37_10"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.6e-37,
                     bitscore: 119.1, seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKPFFSIIIPAYNLENYIAAALQSVLVQTFQDFEIIIVDDGSSD
                     ETVSIIQSFHDPRIRLVSQVNGGVSRARNAGMKKAVGAYIAFMDGDDYWYPEHLELAAD
                     FFNRHPEILAYANRYMRDELAAIPPRPPSYPESIRRLGIRGVLFMNSSSVILNSFLASR
                     LPPLGRSDALWGRRPVLDTVHAGDRPDRAGRLRHLHLQAESFFRHA"
     CDS             7270..7686
                     /locus_tag="ctg37_11"
                     /transl_table=11
                     /translation="MHNEHYQHISLHSLIAPLLNELEAMKNPKWQFAVHYLVIRELHPK
                     RLLSLNVEERISLTGRIRKIMHPCLNRPFLDSYMKACSARAGMEQSFSALMDRTMFSCK
                     WLDRLERMGRFLFFRLQTNNGTESKHQDPVRSRS"
     CDS             7683..7877
                     /locus_tag="ctg37_12"
                     /transl_table=11
                     /translation="MNIVYATDDNGALGTGVSIVSLMENLPLGVHADIYIMTDGLSGDN
                     TARFHSLQQDTISICTSLT"
     CDS             7874..8629
                     /locus_tag="ctg37_13"
                     /transl_table=11
                     /translation="MKDKYTDFPVGSKWSAATYYRLGLAGELPATVERALYVDIDTIFN
                     RDISPMYESEFGDCLIAGVFTTEDLSEESFSRWKREMNLDRDSIYINAGVILYHIGRIR
                     EERFESQVLSWAKNNIHRLSWQDQDILNVCYQQRILLLHPMWNICDGAIWSIRWEGVKS
                     FRNNPLKPADLLEAARRPGIIHYWGHPKPWHPNSIRQDYGLFYKYWKKSPWKDDIRDFR
                     KQNDTGRMFISKMRCLLGKGKRLLQGKHQ"
     CDS             8952..10106
                     /locus_tag="ctg37_14"
                     /transl_table=11
                     /translation="MLILEAGEKGQYGFAAPTDAIEVSDEDALITQVFKTAVPGLPGQN
                     GIRQGENAELKNLTAESGTFAGAVNANGGINIPLTVGAATDTSAVNRLYAAGLAAVTDA
                     FSLRCYPLPADCSSSNGTVFKTDKEPNSLYFNVPPNSSFTVKCGLVTNARPMHNYSSIR
                     GWVAPLRLPSVSAKFTTRFGQMKTVVRMGRDRDAFTLVPDQAAGGYRIGEIIDITFDHV
                     RDAAAGGYHIRVREIYYSNAEQKWKMKTTQALAPETSSNNGYPVCVYAVVYEQYQDGGY
                     DTEDRGALWLLHGGNSTRGCVKIATVRGVHCFENIYPFSGYYLDMENANSWALAGAFLP
                     ATMHLHCNNVNPAYYGFSSMESNIIVSEAVEDFVDPEAETTTED"
     CDS             complement(10160..11722)
                     /locus_tag="ctg37_15"
                     /transl_table=11
                     /translation="MEESRVKKSLLNARVNLIFYVLILLISFFSRKIFLNCLGADFVGL
                     TGTLMSLLNFLNLAELGISTAIGYVLYKPIFEHDETRINEIISVLGYMYRWIGRIIIAA
                     GVALSCFLPVIFPSTGFSYGIIYFAYYSFLASSLIGYFANYRQTLLGADQRNYVVAFYF
                     QTASIIKIICQMLSAWYTGSYYLWIGIELFFGIIYSFILNWKINQVYPWLKSNVALGKE
                     LFKKYPEVTKYTKQLFMHRLGSFFQFQMTPFLVYAFVSLQMAAYFGNYSTIVDKLHLLV
                     NNLLGSTEAGVGNLIAEGNEGKIRKVFSELFSLRMLIAGTVCFPLYQLLEPFITLWLGA
                     EYILPREIMLLLVIRLFITITRGVVDQFLYGYGLFWDVWAPLAESVINISVAIIGGYLW
                     GLPGVLLGGVSSLILIVGIWKPFMLYNWGFRKNVMSYWFQFGYQLALVSISAVFMGWIW
                     KFVPLQPSASFFFWFLCAFLMAVSYGGVTVLLMYCGTQGMRGMVRRALEMAGTRLPWRK
                     KTE"
     CDS             12141..13301
                     /locus_tag="ctg37_16"
                     /transl_table=11
                     /translation="MAAYEMACSLSSLDWDIHVLTRPLDSPEEPFRSRPYSPLTTLPDT
                     LTKNSARLREYLDGFLKDFRPDVIIYHSWADWCREELLDAARDSGIPFFLRSHGAATNF
                     RSFFRFNYPPFFGLKKWLRSFFQIRRNILNVCRKSPLNRLVFLDPYGTLFKRFDYYCAS
                     RSKLAHYSCIPNTFPALKRTAPFFREKYGLSSAPVFTCPAGASMRKRQLLFIRHVKRSR
                     LRHIIFLFLIPQRNAYAEQMEQAIGDDPRFRILYRLPRLEVEAAIMESDAVFLYSYQEQ
                     QPLSILEAMSCGVPWFAPDAGALSTLEGGIVLKNASPSALEKAVESLTDEKTRKLLGSK
                     GRRQWEARFAPDAVNQEWEQLLFSSIRPEGKPPFASSIVREHLPTC"
ORIGIN
        1 ccgtcgctgt cggacggggc ctgcttaggt ttcgtccggc atttccaagt acggtctcct
       61 ggattactgg gaaccttccg gtgtaacatt tattttttac gctgcgcgac gatgaggaag
      121 caactgtctg atattttatt cctggttcaa ggaaacctga taatgaaaaa aactcccgac
      181 agccgatgcc gccgggagtt tttacagagc gtcttaagaa ggaatcttct ttagaaacag
      241 agaccttcct tggcgttggc tcgcatgaag tcgcggttga ggcgggcgat gttgtccacg
      301 ctgatgcctt tcgggcaggc agcttcacat tcatactggt tcgtgcagtt gccgaagcct
      361 tccgcttcca tttgcttcat catggccagg acgcgcttgg aacgttccgg ctggccctgc
      421 ggcagcagat tgagatgggc gatcttggcg gaggtgaaca gcatggcgga ggcgttttta
      481 caggaggcca cgcaggcgcc gcagccgatg caggcggccg cgtcaaaggc ggcgtccgcc
      541 ttcacttttt ccacggcgat gttgttggcg ttcggcgcgg aaccggtacg cacgtcaata
      601 tagcctccgg aggcgatgat gcggtccagg gcggagcggt ccaccatcag gtcccgcagg
      661 attgggaaag ccttcgcgcg gaagggttca atccagacgg tatcgccgtc cttgaacttg
      721 cgcatgtgaa gctggcaagt ggtcacctgg cgttccggcc cgtggggaat gccgttgatg
      781 gtcagggagc acatgccgca gatgccttcc cggcagtcgt ggtcaaaatg gatgggttcc
      841 ttgccttcct tgaccaggcc ttcattgacg atgtccagca tttccaggaa ggaggcgtcc
      901 accggaatgt ccttggcggc ataggtctca atgcggccct tagcttcccg gttttcctgg
      961 cgccagacct tgagagtgag attgagtgtt ttagccatgt tataatcttt cttttgagtg
     1021 ttaatgtatt ggctatcttt acttgtagct gcggatggca aggtgcacgt tctcgaaggt
     1081 cagcggttcc ttgtggagaa caggcaggct gtccacgcca gtgtattccc aggcggctac
     1141 ataggcgtat tcatcgtcgt tgcgcttggc ttcgccgtcc ggcagctggt attccacgcg
     1201 gaagtgggcg ccgcaggatt cctggcggtt cagggcgtca tagcagagca gctgggcgaa
     1261 ttccaggaag tcggccacgc ggcaggcttt ttccagttcc gcgttgatgc cgtccgccgt
     1321 gccggttacg cgcacgtttt cccagaattc cttgcggagc tggggaatgc gttcaatggc
     1381 gtgggtcagg ctttcttccg tgcgggccat gccgcagtct tcccacatga tgaggcccag
     1441 ttcccggtgg aaggagtcca ccgtcttggt gcccttcaca ttcaggagct tgttgatgcg
     1501 ttccttcact tcgtcttccg cagccttgaa ttccggggcg gcggtggtga cggcaccggg
     1561 cttggtggtc gtcaggtaag cgggcagcgt ggcgggaatg acgaagtagc cgtcagacag
     1621 gccctgcatc agggcggagg ctcccaggcg gttggcgccg tgatcggaga agttggcttc
     1681 accgaggacg tgcaacccct tcacgttgga catgaggttg tagtccaccc acaggccgcc
     1741 catggtgtag tgggaggcgg ggtagatcat catgggcgtt tcatgggggt cgtcgtccgt
     1801 gatttcttcg tacatgtcaa acagattgcc gtattggccg tcaatccatt cgcggcccat
     1861 gcgcttgatt tcatccgcaa aatccaggaa gacgcccttg ccggtgacgg ccacgccgcg
     1921 gccgtcgtcg caggcttcct tggcggcgcg ggaggaaatg tcgcgcggag ccaggttgcc
     1981 gaaggaggga tacttgcgtt ccaggtagta gtcccgttct tcttcgggaa catcggaagg
     2041 cttgatttcc ttcttacgga ttttttctgc ggtttcacgg gacttgggca cccagatgcg
     2101 gccgctgttg cggagggatt ccgacatcag cgtcagtttg gactggtagt cgcctttgac
     2161 cggaatgcag gtggggtgga tttgcgtgaa gcaggggttg gcgaagaagg caccacgctt
     2221 gtaggctttg taggcggcag tgacgttgca acccatcgcg ttggtggaca ggaagaacac
     2281 gttgccgtag ccgcccgtgc agagcaggac ggtatcccct gcgtaggatt tgatttcgcc
     2341 ggtaaccaga ttgcgggtga cgatgccctt ggcttcgccg tccaccaaca ccaggtccat
     2401 catttcatgg cgggagaaca tttcaatgtg tcccttggcc acttcctttt ccagggcctg
     2461 gtaggcaccc agcaggagct gctggcccgt ctgtccgcgt gcgtagaagg ttcgcttgag
     2521 ctgggcgccg ccgaaggagc ggttgtccag caggccgccg tattcacggc cgaagggaac
     2581 gccctgggcc acacactggt caatgatgtt ggaggagact tccgccagac ggtagacatt
     2641 ggcttcacgg gcgcggaagt cgccgccttt aacggtgtcg taaaacaggc ggtaaacgga
     2701 gtcgccgtcg ttctggtagt tcttggccgc gttaatgccg ccctgggccg caatggagtg
     2761 ggcgcggcgg gggctgtcct ggtagcagaa gcatttgacg ttgtagccaa gttcggcaag
     2821 cgtggcggca gcggaggcgc cagccaggcc ggaacctacc acaagtaccg tgtacttgcg
     2881 cttgttgttc ggattgatca gtttggactc aagtttgtac ttggaccatt tgtcctgaat
     2941 agggccggag ggaattttgg catccggcat ccagtcgctt acgggaaaat taatcatgac
     3001 tttgagagga gttgatggtt atttgatgat acccagaaga accgagaccg gcacggagat
     3061 gaagcccagg cagataatcg cgccgtaggc gatggcgata aagttgtaga agggccggat
     3121 tttgcgggaa tcgacgccca cagtctggaa gatggactgt accccgtggc gcagatggct
     3181 gaacagcatc agaacggcca ggatgtagaa ggcggagcac catacgttgg agaatccggt
     3241 cacgatcatc ttgtacacgt caaaggtttc caccgtaccg tcggaaataa aggtggtgaa
     3301 ctgggcgggg tcgtatccca cgcgcagggt gtactggtac aggtggtaga tcaggaacac
     3361 caggacggtc aaaccggtgt aaatcatgta gcgggaggag agcgttgcct taatggtgtt
     3421 cttgaacacg tagggttcgc gggccgcatg gttttccagc ttcagctgga tggtcagcca
     3481 gacgtggatg atgaagatca ccgcaagccc cgcgcggatt ccccagaggg ctgcttccgg
     3541 catggagtgc aggccgtggg cgtaggtgtt gatccattca gggcctccga agatgagaag
     3601 gttgcctgcc aggtgtcccg caaggaacaa gaccaaacat aaccccgtca gagccacaat
     3661 gattttgcgg ccgatggagg atgtcacgaa tgtacatatg gtttttacta gtgcattcat
     3721 aggcgctcta atgaaataaa tgcgtcttca caggatgccc ggttcaagcc cggatggcaa
     3781 gcctcttctt gaatttccgg cgcttttcgg atttttgaaa aaccggggaa agaggttgct
     3841 gtttatcagt ttggaatggt tatcattttg ttgcctgttc cggcttgacg aggctttccg
     3901 cacaggcgta tcgtctgtgc atgaaaagaa gtaaaaagga ggtgctggac gcggatttcg
     3961 cagcgacgcg cgccggcgtt ctggatgtgg ccgcatttct ggaccgggtg gaccgcgggg
     4021 aaggggaggc ggatttccgc taccatgccc tgatggatgt tcttcccctc ttgtccgcat
     4081 ccggccccgg acgcgtccgg gccattctgg aagccctttc ctacagggat gacaccgtgc
     4141 cggaaaccgc cgcagccaaa gcggcctgcg gagccccgaa cctcagcaaa taagaatgat
     4201 ggctttcata gaacctcata tacatatggt gtgccgcacc acggacgaat accgggccat
     4261 ggcgcaggcc ggctgcctgg cggtagggga accggcgttc tgggccggtt acgaccgttc
     4321 gtccgcggac ggtttccggg attatttcgt acagcttacg gaatgcgaac ccgccagggc
     4381 ggccaagttc ggcatggacc attacacatg gctgtgcatc aatcccaagg aggcgcagga
     4441 cgtggctttc gcgcgggatg tgatgaaact gattccggag ttcattgacc ggcccaatgt
     4501 cctcggcatc ggggaaatag ggctgaaccg gaatacttcc catgaaatga ctatttttga
     4561 agagcatctg gatctggcgg tgcgcctcaa ccagcttgtg ctgattcaca ctccccatct
     4621 ggaagacaag cttaagggga ccgtaatgat tctttccgcc ctgaaaaacc gtccggatct
     4681 ggacccttgc cgcgtgctgg tggatcactg tgaggaacat accttcccgc tggtgaagga
     4741 ggccggttac tgggccgggc tgacccttta tcccaccagt aagctgaatc ccaagcgggc
     4801 ggcggatatt ctggaattgt acggaatgga ccgtgtctgg gccaattccg cggcggactg
     4861 gggggattcc gatcccctgg cgctgacggc cctggcctgc gagctacgca ggcgcggttt
     4921 ttcccggcag gaaacggaac gtcttctcct ggaaaatccg gagacattca tgggacagtc
     4981 cccgaagttc cggaaagtgt cgtcccgcta attccgcccg aggcgcggcg gagggtacgg
     5041 ccctctagtc cccgtccggg aaaaagacgg tgaggacggc gcccaggatg accgccgcgt
     5101 catccagaag gcccagcctg ccgattccgt caaacaggaa ttcgtcggga gtcaggatgt
     5161 aggcgccggc ggcggccaga aggcatatat tccgtttgtt gaaaaaacgc ggttctcctt
     5221 ttctgctttt gaaataccgg aacaggcgca gtagcagctg ctgtttttga aggttcatgg
     5281 acgggaacgg gggataaagg ttcaagctca gccattttcc cactcctttt ccctgtttcg
     5341 gggaaggagt ctgttgccga cggacggaaa ccgcagcgat ccggaccgtg cggggaaatg
     5401 gattgctgaa aggatgggct gttccggatg ctgagggaag ccgggctttg catgctccgg
     5461 ttccggctgt cccggcatgg gaaaaagggg cgtgtacgga agtggggcgg ggccggaagc
     5521 tcttgaaatg accctcccgg gggagcctga atgccatttc cccgtcaagt gctggccgtg
     5581 agggtaccgc agcaaatgga agcttcttcc cccctgtttt ttccggcaga tgtttgaacg
     5641 gataaggaaa aggccggctc acgattttgt gagccggcct ttgaatatag ggaggcggac
     5701 ggtacaggct tatgccctgc ggcggcgcat catcagcgcg gccagtccca gcaggcccag
     5761 ggaagccgtg gcgggttccg ggatgctggc gatttcactc atcagttgac caacttgttc
     5821 ctgggaaagg agggagtcgt gaatgtagag ctgttcgatg gattcagcca gtcctgcgtc
     5881 catgagaatc tgatcaattt gctggttgcc gaatttcagg ccgctgttgg aatagtacgt
     5941 agtgctgtct ccaaaataga tgcgggtgcc aagatctccg gtgactacgg aaatggtcag
     6001 ggaaccttcc gtgcccagcg gggtgtcaac gacaggcccg ctgtaggagg tgttgttcca
     6061 taatccctgg agtttccggt ccgtgttcag gcccacgccc cagcttacac tgctgttttt
     6121 ggcgttaaac agagcggtat aggcgtccgg agtgttgatt ttggacaggt caagaaccat
     6181 cgtcacagac ataacgtcgc ggttgttggc accgtatccg ttgaaggtta tcccggataa
     6241 cgtcagattg ctgtcgtcag acgtgatgga aacggaatct ttcagggtgc cgaaatccgc
     6301 cgtttgggag gcaaagtccg aatatcccac gatggagcta tccagcagag aggtagccgc
     6361 ggtagcgctt aggctcatgc cgaccgaaag aatcagggtg gataataatt tattcatggt
     6421 cagtatctta ataaaatgat gcaagattca atgtatgtac ttgtgcttga ataacgaatt
     6481 tggaattcgc tatgacaggt tcattcgcgc gctgatgaat catgggagga acgatggatt
     6541 cgtccccctg ccattcaccg gttgcgatag ttacaacccc atcagaatca tgttctccat
     6601 atcttggttc ccgttctatt cacgaagcag ttcatcattc cccttacatg cagaaaccgt
     6661 tcttcagcat tattatcccg gcttataatc tggagaatta tattgctgcc gcccttcagt
     6721 cagtactggt tcaaacattt caggattttg agatcatcat cgtggatgac ggttcttccg
     6781 atgagaccgt ttccatcatc caatcttttc atgaccccag aatccgcctg gtttcccaag
     6841 ttaacggcgg cgtgtcgcgg gcgcgaaacg cagggatgaa gaaggccgtg ggggcttaca
     6901 tcgctttcat ggacggagac gattactggt atcccgagca tctggagctg gcagccgatt
     6961 ttttcaaccg tcatccggag atattggcct atgccaaccg ctacatgagg gatgaactgg
     7021 cggccatccc gccgcgccct ccatcttatc ccgaatctat ccggaggctg gggatacggg
     7081 gagtgctttt catgaattcc agcagtgtaa tcctgaattc gtttcttgcg tcccggcttc
     7141 cccccctggg aagaagcgat gccctatggg gaagacggcc tgtactggac acggtgcatg
     7201 cgggggacag gcctgatcgg gctgggaggc tccgtcacct ccatttacag gcagagagct
     7261 tcttccgcca tgcataatga gcattaccag catatctccc tccactcgct cattgcgcct
     7321 ctgctgaatg agcttgaagc catgaaaaat cccaaatggc aatttgccgt tcattatctg
     7381 gtcatcaggg aattgcatcc caaaagactg ttatcgctca acgtagagga acggatttcc
     7441 ctgacgggca gaatcaggaa aatcatgcac ccatgcctga accggccgtt tttggactcc
     7501 tatatgaaag cgtgttccgc aagagcaggc atggaacaat cattttccgc tctcatggac
     7561 agaaccatgt tctcctgcaa atggctggac cgcctggaaa ggatgggacg cttcctgttt
     7621 ttccggttgc aaaccaataa cggaacagag agcaaacacc aagatccagt ccgttcacga
     7681 tcatgaatat cgtatatgct acagacgata acggcgcgct gggaacgggc gtgagcattg
     7741 tgtccctcat ggagaatttg ccgctcggcg ttcatgccga tatttacatc atgactgacg
     7801 ggttaagcgg ggataatacg gcccgtttcc attccctgca acaggataca atctccattt
     7861 gcacttcatt gacatgaagg ataaatatac ggatttcccc gtcggttcca aatggtcggc
     7921 ggcgacgtat taccgtcttg gcctcgcagg ggaacttccc gccacggtag aacgcgccct
     7981 ttacgtggat attgatacca ttttcaacag ggacataagc cccatgtatg aatccgaatt
     8041 cggagattgc ctcattgccg gcgttttcac cacggaagat ttatccgagg aatctttttc
     8101 acgctggaag agagaaatga atctggaccg ggactccatt tacatcaatg ccggcgtcat
     8161 tctttaccat atcggaagaa tacgcgaaga acgttttgaa tcccaggttt tatcctgggc
     8221 gaaaaacaat attcaccgcc tttcctggca ggatcaggat attttgaatg tatgctatca
     8281 gcagcgtatc ctgttgcttc accccatgtg gaacatttgc gacggggcta tctggtccat
     8341 tcgttgggaa ggcgtgaaaa gcttcagaaa taatcccctg aagccggcag acctgctgga
     8401 agccgccagg cggccgggca ttatccacta ctggggccat cccaaaccct ggcatcccaa
     8461 cagtattcgc caggattacg gattgttcta caagtattgg aagaaatctc cgtggaaaga
     8521 tgacatcagg gatttccgga agcaaaacga taccggccgg atgttcatct ccaaaatgag
     8581 atgcctcctg ggaaagggta aacggctttt acagggcaag catcaataga aatacggagg
     8641 gagggcttta tattttcctg atgcccagcc tatttactgc gtcgcctttt atggggaaat
     8701 gccagagccg gctatttttt aacaagccga cttaactccc ctccggaatt ttcccgaatc
     8761 cgggagaaac cgtccgcata tgccttcagg aacgcctcaa cgttttatgc ctgatgattt
     8821 ttccggagtt ttatcaatag taaaaaaatc attcatttat gaaagttgat accattaagg
     8881 gaagttccta tgtcatgacc tgtacaaaag cttgtactgt aagcgccatt ttcaattccg
     8941 gagagacgtc catgcttatt ctggaagcag gggaaaaagg gcaatacggt tttgcggccc
     9001 cgacggacgc catagaagta tccgatgaag acgctttgat cacccaggtt ttcaaaacag
     9061 ccgttccagg gctgccgggc cagaacggca tcaggcaagg agaaaatgcc gaattaaaaa
     9121 atctgacggc tgagtccggg acttttgcag gggccgtcaa cgccaacgga ggcatcaata
     9181 tcccgctgac cgtgggggcg gcaacggata cgtcagcggt caaccgcctg tacgccgccg
     9241 ggctggctgc cgtgacggac gctttttccc tcaggtgcta tccgctcccg gcggattgct
     9301 cgtcttccaa cgggacggtt ttcaaaacag acaaggaacc caattccctt tatttcaatg
     9361 tccctcccaa ttcctctttt accgtgaagt gcggccttgt gaccaacgcg aggcccatgc
     9421 acaattattc cagcatccgg gggtgggtgg ccccgctgcg cctgccgtct gtcagcgcta
     9481 aattcacgac caggttcggc cagatgaaaa cggtcgtgcg catgggaagg gacagggacg
     9541 catttacgct ggtgccggat caggcggcgg gcggctacag gattggggag attatcgata
     9601 ttacgtttga tcatgtccgg gacgcggccg caggggggta tcacattcgt gtccgggaga
     9661 tttattattc caatgccgag cagaaatgga agatgaagac gacgcaggcc ctcgcgccgg
     9721 agacgtcttc caataacggt tatcccgtct gcgtgtacgc ggtggtttac gagcaatacc
     9781 aggacggagg atatgatacc gaagacaggg gagcgttgtg gctgctgcat ggcgggaatt
     9841 ccacccgcgg ctgcgtcaag atcgccacgg tgaggggagt ccattgcttt gagaatattt
     9901 atcccttttc cggatattat cttgatatgg agaatgccaa cagctgggcg ttggccggag
     9961 cgttccttcc ggcgacgatg cacttgcatt gcaataatgt caatccggcg tattacgggt
    10021 tttcctccat ggagagcaat atcattgtct ccgaggcggt ggaggatttt gttgacccgg
    10081 aagccgaaac gactactgaa gattgagcat aaatgacgca gcgtccccat tcccgatgcc
    10141 cggcaacacc tctgcgtccc tattcagttt ttttccgcca cggcaaccgg gttcccgcca
    10201 tctccagcgc acggcgcacc attccgcgca tgccctgcgt accgcaatac attaaaagaa
    10261 ccgtcactcc gccataagag acggccatga gaaaggcgca taagaaccag aagaagaaag
    10321 atgcggaagg ctgcagggga acgaatttcc agatccagcc catgaacacg gccgaaatcg
    10381 aaaccagcgc cagctggtaa ccgaactgga accagtaact catcacattt tttctgaatc
    10441 cccagttata cagcatgaag ggcttccaga tgcccacaat aagtatcagg ctggagactc
    10501 cccccaacaa aacgccgggc aatccccata agtaacctcc gatgatcgcc acggaaatgt
    10561 tgatcacgct ttccgcaaga ggagcccata catcccagaa caaaccgtaa ccgtataaaa
    10621 actgatccac aaccccccgc gtaatggtga tgaacagcct gatgacaagc agcagcatga
    10681 tttcccgggg aaggatatat tccgccccca gccaaagcgt gatgaatggc tccagaagct
    10741 ggtaaagggg gaaacatacc gtcccggcaa tcagcatgcg cagggaaaac agctcactaa
    10801 acactttgcg gatttttccc tcatttccct ccgcaatcaa gttgcccaca ccggcttccg
    10861 tactgccgag cagattattg accagaaggt gcagtttatc cacaatggtg gaatagttgc
    10921 cgaaataggc cgccatctgg agggaaacaa aggcatatac cagaaacggc gtcatctgaa
    10981 actggaaaaa gcttcccagc cgatgcataa acaactgctt ggtgtattta gtgacttcag
    11041 gatatttttt gaacagctcc ttccccaggg ccacattgct cttcagccag ggatagacct
    11101 gattgatctt ccaattcagg atgaaggaat aaataatgcc gaagaacagt tctatcccta
    11161 tccataaata atagcttccc gtataccatg cagacagcat ctggcatatg attttgatga
    11221 tggatgctgt ctggaaataa aacgccacta cgtaattcct ctggtccgct cccaaaaggg
    11281 tctgcctgta gttggcgaaa tacccgatca gggaagaggc cagaaaggaa taataagcaa
    11341 aatagatgat tccataggaa aagcccgtgg aaggaaaaat aaccggcagg aaacaggaaa
    11401 gcgctactcc agccgcgatg attatccgcc ctatccaccg gtacatgtat cccagcacgg
    11461 agataatttc attaatcctg gtctcatcat gttcaaagat cggcttgtaa agcacatacc
    11521 cgatagccgt gcttatgcca agttccgcca aattgaggaa attcagcaga ctcattaatg
    11581 ttcccgtcaa accgacaaaa tcggcaccca ggcaattcaa gaatatcttt cttgaaaaaa
    11641 aggaaatgag aagaatcaaa acataaaaaa tgagattgac cctggcgttc aacaggcttt
    11701 tctttacgcg ggattcttcc atgttattta ttccatcaac cttatccttt cccgggagaa
    11761 gttaaaaata tctgttttat taataaccgg attatttatt caaccggcaa tataccaacg
    11821 gcatattgcg gccatacggg tacggaaagc ggtgccaatc tagcacaaca tcctgccgca
    11881 tcaatatctt tttatgaagc ctcagccaac aggcttccac aggggataga aaccggtcag
    11941 aatcgcctgt tcccatgacg cctccttatc gctcaccgga taaaaaacaa attcctcatt
    12001 tttacaggtt ccatggaccg gaacagttcc ataaagtgtc cttgttttat tttttctttt
    12061 catctacatt accgcccgtg agcaagggca gggttctcat cgttacatat gtttttcctc
    12121 cggaggaagg aggcgtaggc atggctgcct atgaaatggc ctgcagcctg agctccctgg
    12181 actgggatat ccacgtcctc acccgcccgc tggattcacc ggaggagcct ttccgctccc
    12241 gcccatacag ccctctcaca accctgccgg acaccctgac aaaaaacagc gcccgtttaa
    12301 gggaatacct ggacgggttt ctgaaagatt tccggccgga tgttattatc taccactcct
    12361 gggcggactg gtgccgggaa gaattgctgg acgcggcgcg ggattcaggc attccgtttt
    12421 tcctccgctc ccatggtgca gctaccaatt tccgctcttt tttccgcttc aattaccctc
    12481 ctttcttcgg cctgaaaaaa tggctccgct ccttttttca aatacgcagg aatatcctca
    12541 acgtatgcag gaaatcaccg ttaaaccgtc tcgtttttct cgacccttac gggacactgt
    12601 tcaagagatt tgattattac tgcgcatcca gaagcaaact tgcccattac tcctgcattc
    12661 ccaacacatt cccggctctg aaaagaaccg ctcctttttt ccgggaaaaa tacggacttt
    12721 cctccgcccc cgttttcacc tgccctgccg gcgccagcat gaggaaacgg cagcttctct
    12781 tcatccgcca tgtgaaacgc tcccgtctgc ggcatatcat ttttcttttt ctcattcccc
    12841 agcgcaatgc ctacgcggaa caaatggaac aggccatcgg tgatgacccc agattcagga
    12901 ttctctacag gctcccccgt ttggaggtag aagccgccat tatggaaagc gatgccgttt
    12961 tcctttactc ttatcaggaa cagcagcccc tctccattct ggaggcgatg tcatgcggcg
    13021 ttccctggtt cgctccggac gcaggagctc tttccaccct ggaaggggga atcgtcctga
    13081 aaaacgcatc cccctccgcg ctggaaaaag ctgtggaatc gttgacggac gaaaaaacac
    13141 gcaaactact ggggagtaaa ggccgccggc aatgggaagc ccgtttcgcc cccgacgcag
    13201 taaaccagga atgggagcaa ctgctttttt cctccatccg cccggaagga aagcctccgt
    13261 tcgcgtcttc catcgtccgg gagcatttac ccacctgcta accttgcctc cttttttcca
    13321 atccatgccg accaaacgcc tccgtcccgt attagccata gcagcggacc tccctctggg
    13381 ccggctgctg acgtctttcc gtaacaaaga ccggcgtacg attccctgga ttttttccct
    13441 ttttcatgct ctggaatctc aggaagattt tgacatccac tggattactc tcagcaaagc
    13501 cgtttccgcc gcggaaacca tccggatgcg caaccagacc atccacatcc ttcccctggg
    13561 cagcatgggc aggaatatcc tgacggccca tttcctgacc gtccggagaa tacgcaagac
    13621 tctgaacgat atccagccgg atctcctgca cgtatgggga gtggagcagg cttacgctct
    13681 ggcggggatt accttccggg gaaagaagct cctttcctac
//
