LOCUS       c00024_gnlPro..        13702 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PNLFACFB_24.
ACCESSION   c00024_gnlPro..
VERSION     c00024_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 05:50:36
            Original ID  :: gnl|Prokka|PNLFACFB_24
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 22725
            Orig. end    :: 36427
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13702
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[32725:36215]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13490
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13702
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13702
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(542..1132)
                     /locus_tag="ctg24_26"
                     /transl_table=11
                     /translation="MSGLANAFLALLPPDQASLPAAGAEARWLADTAVVQSAAIARDNR
                     TVLFGWLNNILVNSNLRDRGLCWQVQQDLYRDLRRRPVKYFRIGLTIRDRGTGREHSCV
                     YVNAAGKGLQGSIVLDAWKNCGHLVTLTQKDREGGKWEEDWREPFVSKAFPEGHSYGME
                     HHLVWPGWARKRPMLVQRIFQSDQQNEAKAAAE"
     CDS             1372..2982
                     /locus_tag="ctg24_27"
                     /transl_table=11
                     /translation="MLTIKNLTKSHAGRTLFRETEMTINWGERVALVGPNGAGKSTLFR
                     MILGEDTPDEGSISMDEYAIVGYLPQEASEPKDETVLEIALGITPEMEQAIHTIRTAEN
                     ANKTDTPEYAEAIDTFNAANGYQLEPKAKKILKGLAFRESDFHRPAREMSGGWIMRAYL
                     AKLLVLEPDLLMLDEPTNHLDLLSLLWLQRYLKNYPGAILMISHDRDFMDELVESVYDI
                     DNEELVEYRGNYSDFLQQKDVRFEQLQAAYRNQQKEIAHIQEFIDRFRSINSKAGQVQS
                     RIKQLEKMKIIQKPVARRKVFKFNFPQPPRSTQKVIELEKVCQSYGDRRVYENLDLLVE
                     RGERTVLVGPNGAGKSTLLKILAGIIPIDSGQRTPGTTTRIGYFSQARTENLNPENTVL
                     EEIMKCSAEIREEEARSILGSFLFRRLDVEKRVSVLSGGEKSRLSLVKFLVDPPNLLLM
                     DEPTTHLDLLSVEALVQALKHYEGTLVFISHDVHFIRSLAQKTLHVNRGTITAYAGGYD
                     YYLEKSGILDDEKGGITAE"
     CDS             3225..3563
                     /locus_tag="ctg24_28"
                     /transl_table=11
                     /translation="LAGVQDKESADNAVKTLQDIQKDIRHFLQLQDKLNDAEKEKEDAL
                     IEKMKKRMEMLDNRCRQEGKRPFEARYYGSAALKDILENSDEFSGLVEPDEDGAPPNAI
                     RENEEAGQ"
     CDS             3665..4438
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg24_29"
                     /sec_met_domain="adh_short_C2 (E-value: 5.3e-75, bitscore:
                     243.3, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKNGFTVGSMQKLAGKTAIVTGAGRGIGNAVARRFASEGARVILI
                     SRSPSSCGGAAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFLQIDILVNNAGIT
                     RDSLMLRMKEEDWDAVLDTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQA
                     NYAASKAGLIGFTKSLALEFAPRKVTCNAIAPGFISTEMSNAIPDNLKEEIVKKIPLKE
                     QGSVEDIAALTAFLASDDARYITGQVIACDGGMTM"
     CDS             4819..5667
                     /locus_tag="ctg24_30"
                     /transl_table=11
                     /translation="MGSPAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFMENGR
                     PRAKDGQLLEEQPDDELWDSVTQPTAPYAAMNLGMGHGYEHGLPAISMSHHAASKFCEW
                     LSAQTGHYYRLPTEAEWEYACRAGSAGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSKK
                     PNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPTKDPLVIIPGAPHIVRGGSWEDDPDS
                     LRSAARRASTPAWNRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDIMTMHRLWNFSKGE
                     P"
     CDS             complement(5711..5896)
                     /locus_tag="ctg24_31"
                     /transl_table=11
                     /translation="MTDVASTMFPDDAAAVDGDCILLRDEGRTDAHDMEQVMFIAAGDE
                     IVSERFSRDMFRFGMV"
     CDS             5934..6371
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg24_32"
                     /sec_met_domain="Acetyltransf_1 (E-value: 1.8e-08,
                     bitscore: 26.1, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGPIAVLPEYQRRGIGRRMIGYTRNRAREMGFRAIFLYGDPDYSS
                     HCGFVPAETLGIRTADNRYAAALQVCALQRGSLSGLKGRYVEAAVYHMDEKRAAEFDRH
                     FPVKKKLSGIASQKRFQQIAAMRRKPDTAPCPRKSRTFRRA"
     CDS             complement(6473..7213)
                     /locus_tag="ctg24_33"
                     /transl_table=11
                     /translation="MKKTLTLLIAMGSFAVSSEAATVFNYYTPGTDNYNSTIHGFYLSL
                     GSSSLAPSDSSSPSSLSGEIRLDSFTLRGAANNLGANVTYGFLVLNGSDNSVIGWSTNT
                     GTTAAGINLTFSFSSLDGSPLLLDAALTYRFLAVSQSVMGLMQDTSKTYLYAAGGTAAP
                     TANTEGDTVTISGGLTAPGIRGHYDAEGAPGDSVVITGANGTNTFSLLSPIFTEIRGEM
                     VPEPATVSLGLLGLAALMMRRRRA"
     CDS             7318..8025
                     /locus_tag="ctg24_34"
                     /transl_table=11
                     /translation="MNKLLSTLILSAGMSLSATAATSLLDSSIVGYSDFASQTADFGTL
                     KDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPDAYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYNGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYS
                     NSGLKFGNQQINQILMDAGLAESIEQLYIHDSLLSQDQIGQLMSEIASVPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             8450..8713
                     /locus_tag="ctg24_35"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLCRYFKSRKGEPRFFNKRNICLLAAASAYILTPD
                     EFLFDGIGKLGLLDDAAVILGAVLTVLFSGWRLTARTHRRRN"
     CDS             complement(8710..9525)
                     /locus_tag="ctg24_36"
                     /transl_table=11
                     /translation="MMAFIEPHIHMVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSVD
                     GFRDYFVQLTECEPARAAKFGMDHYTWLCINPKEAQDVAFAREVMKLIPEFIDRPNVLG
                     IGEIGLNRNTSHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLD
                     PCRVLVDHCEEHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADW
                     GDSDPLALTALACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(9528..9779)
                     /locus_tag="ctg24_37"
                     /transl_table=11
                     /translation="VLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYRALMEVLPLLS
                     ASGPGRVRAILEALSYRDDAVPETAAAKAACGAPNLSK"
     CDS             10001..10702
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_38"
                     /sec_met_domain="SucD_FumR (E-value: 3.7e-13, bitscore:
                     40.9, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLGVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLVYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             10724..12682
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.1e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_39"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.7e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 7.8e-38,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAITGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTASPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             12723..13490
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.5; E-value: 8.6)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_40"
                     /sec_met_domain="Fer2_3 (E-value: 1.5e-23, bitscore: 74.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 4.9e-11, bitscore: 34.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.8e-06, bitscore: 19.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENRDAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPERQVTTCQLHMRKFKDGDTVWIE
                     PFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAPNANNIAVEKVKADAAFDAAAC
                     IGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSKRVLAMMKQMEAEGFGNCTNQY
                     ECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(13557..13700)
                     /locus_tag="ctg24_41"
                     /transl_table=11
                     /translation="VQCIPLIDINVVCLLENVPDRWPLFLATVKFPGRGYLVFYSWLKE
                     TR"
ORIGIN
        1 cggttttgaa acaatccgtt ttccataacg catcaaaaag agcaggactt cagaaaccgg
       61 gggtcctgct cttttctgta atgccgtgac atggaacaag aaaatctctt gatttctact
      121 tgccaccatt tacattggtg ccagcaaacc tccgtggatg cggaggttcc agtagttaac
      181 aaacactgta tttaattcga attatgaaga acatcgctat cctcgccatc gccggcgccg
      241 cttgcttggt cgcttcttgc tcccagcagc agcagcaaca gcaaaccacc gctcctgctc
      301 ccgctccggt tgtgcaggcc aagggcaagt aagtttgcag cggggttttg ccctgcaaca
      361 ctagcaaatt atccaattaa tccgcactcg gtgtacgcac tgagtgcgtt tttatttgcc
      421 ctgagtccgg attccctccg ccatttgccg attcgccggg attttcctta aaaacggcgg
      481 ataccgcaaa ccgccgcggc gcagcaccgt gtgccggttc ttgccggatc aggcttcccc
      541 tttattcagc ggccgccttc gcctcattct gctgatcgga ctgaaatatc cgctgaacca
      601 gcatggggcg tttcctggcc cacccgggcc agaccaggtg atgttccatg ccgtaggaat
      661 ggccctccgg aaaggccttg gaaacaaatg gttcccgcca gtcctcctcc catttgccgc
      721 cttcccggtc cttctgggtc agcgtcacca gatgcccgca gttcttccag gcatccagaa
      781 caatggagcc ctgcaatccc ttccccgcgg cattgacata cacgcaactg tgctccctgc
      841 ccgttccacg gtctcgaatc gtcagcccta tgcggaaata cttcacgggg cggcggcgca
      901 ggtcccggta caaatcctgc tggacctgcc agcacagccc cctgtcgcgc aggttggaat
      961 tgaccagaat attgttcagc cagccaaaca gcacagtcct gttgtcccgg gcaatcgctg
     1021 cggactggac cacggccgtg tccgccagcc acctggcctc cgctccggca gcgggaagag
     1081 aggcctgatc cggcggcagc agcgccagga aggcattagc cagcccggac atttgctgct
     1141 gcacgtaagg ttgttgtata taatcctccg ccggaggagt acagcaggaa ctccatccgc
     1201 acaaaagggc ggcagcaagc aaaagcctga atgtctgcgt ggtcggcatg gcgcgccaag
     1261 gctagcagac tacgcgtaaa aatccagtaa agctttcaaa aatgcctgcc tccgccctga
     1321 cggctcttgc cttccccttt ccatcccggt agaatacatc ctctcttcac catgctgacg
     1381 atcaaaaatc tcacaaaatc ccacgccgga cggaccttgt tcagggaaac ggaaatgacc
     1441 attaactggg gggaacgggt ggctctggtc ggccccaacg gagcaggcaa atccaccctg
     1501 ttccgcatga ttctgggaga agacacgccg gacgaaggct ccatcagcat ggatgaatac
     1561 gccatcgtgg gctatcttcc ccaggaagcc agcgaaccga aggatgaaac cgtcctggaa
     1621 atcgccctgg gcatcacgcc ggaaatggaa caggccatcc acaccatccg gacggcggaa
     1681 aacgccaaca aaacggatac gccggaatac gcggaagcca ttgacacctt caacgccgcc
     1741 aacggttacc agctggagcc caaagccaag aaaattctca aagggctggc ctttcgggaa
     1801 agcgacttcc accgccccgc ccgggaaatg tccggcggct ggatcatgcg cgcgtacctg
     1861 gccaagctcc ttgtcctgga gccggacctc ctgatgctgg acgaacctac caaccacctg
     1921 gacctcctgt ccctgctgtg gctccagcga tacctgaaaa actaccccgg agccatcctg
     1981 atgatttccc acgaccggga tttcatggat gagctggtgg aaagcgtgta cgacatcgac
     2041 aacgaagaac tggtggaata ccgaggcaat tactcggact tcctccaaca aaaggacgtg
     2101 cgcttcgagc agcttcaggc ggcctaccgc aaccagcaga aggaaatagc gcacattcag
     2161 gaatttattg accgtttccg ctccatcaat tccaaagccg ggcaagtcca gagccgcatc
     2221 aagcagctgg aaaagatgaa aatcattcaa aaaccggtag cccgcaggaa ggtatttaaa
     2281 ttcaacttcc cccagcctcc gcgcagcacc cagaaagtca ttgagctgga aaaagtctgc
     2341 caatcctatg gcgaccgcag ggtttatgaa aacctggacc tgctggtgga acgcggggag
     2401 cgcactgttc ttgtaggtcc gaacggcgcg ggcaaatcca ctcttctcaa aatcctggcg
     2461 ggcatcatcc ccattgactc cggacaacgc actcccggta ccacgacgcg catcggctac
     2521 ttctcccagg cgcgaacgga aaacctgaat ccggaaaata ccgtgctgga ggaaatcatg
     2581 aaatgcagcg ctgaaatccg ggaggaagaa gcgcgttcca tcctgggttc cttcctgttc
     2641 cggaggctgg atgtggaaaa acgcgtcagc gttctttccg gcggggaaaa atcgcggctc
     2701 agcttggtca aattcctagt ggatccgccc aacctcctgc tgatggacga gccgaccacc
     2761 cacctggacc ttttgtccgt agaagccctg gtgcaggctc tgaagcatta tgaaggaaca
     2821 ctggtcttca tctcccacga tgtgcacttc atccgttccc tggcacaaaa aaccctgcat
     2881 gtgaaccggg ggaccatcac cgcctacgca ggcggatatg actactatct ggaaaagtca
     2941 ggcattctgg acgatgaaaa aggcggcatc acggcggaat aaggctcttt tttcagtttc
     3001 ccctttttcc ttgccgtgga tttcatcctg cctcaaaaga acaggatgaa ggcttttctt
     3061 gttcctctct tatattctgc gcttctgtcc ggagcctctc ttgcatttgg tgaaacggcc
     3121 gccggaacgg cttccccaca gcagcggctc cggcggaaaa aattccttcc gcggaatccc
     3181 tgatcaacca ggccttttcc tttgccatca atatccagca gacgttggca ggcgttcagg
     3241 acaaggaaag cgcggacaac gccgtcaaaa cgctgcagga cattcagaag gacatccggc
     3301 atttcctcca gcttcaggat aaattgaacg atgcggaaaa ggagaaagaa gacgccttga
     3361 tagaaaaaat gaaaaaacga atggaaatgc tggacaaccg ctgcaggcag gaaggcaaac
     3421 gcccgtttga ggcccgttat tacggttccg ccgccttaaa ggacattttg gaaaattcgg
     3481 atgaattcag cggcctggta gaaccggatg aagacggggc gccccccaat gcaatccggg
     3541 aaaatgaaga ggccggacag tagcctcccc ctcaccccgt ttctccccct tttttcattc
     3601 ccggcccgcc ctttccccat atggggtcct gcgcggccag gtccatttca agcttgccgg
     3661 aaccgtgaaa aacgggttta ctgtgggcag catgcaaaag ttagcaggta aaacagccat
     3721 cgttaccggc gcgggtcgcg gaatcggcaa tgccgtcgcg cgccgcttcg cttcggaagg
     3781 agccagggtc atcctgatca gccgcagtcc atccagctgc gggggagccg cagaagaaat
     3841 caacaaggaa tttccggatt cctgcaaggc ctacccctgc gacgtagcgg attacgcggc
     3901 cgttcaggaa accatggccg ccattttgaa agacttcctg cagattgaca tcctggtgaa
     3961 caacgccggc atcacgcggg actccctgat gctccgcatg aaggaggaag actgggatgc
     4021 cgttctggac accaacctga aaagcgcgtt caatacggtc aaggccctcc agcgtgttct
     4081 catgaaatcc ccggccgggc gcatcatcaa catgagctcc gtcatcggtc tcgtcggcaa
     4141 catcggccag gccaattacg ccgcttccaa ggcgggcctc atcggcttca ccaaatcact
     4201 ggccctggaa ttcgctccgc gcaaagtcac gtgcaacgcc attgctcccg gcttcatctc
     4261 cacggaaatg tccaatgcca ttcccgacaa tctcaaggaa gaaatcgtca agaaaatacc
     4321 tttgaaagaa caaggttccg tggaagatat cgccgccctg acggccttcc ttgcctctga
     4381 cgatgcccgt tacatcaccg ggcaggtcat tgcctgcgac ggaggcatga cgatgtaggg
     4441 cattccggtt ttcaccattc catgcgcggc attttccttg tttcctgctt tctgggagga
     4501 agcgccctgc tggccgggtg ccgggaagaa aataattccc cccgcccggc cacggaagat
     4561 gccgcgcgca ttaccagcgc acgccagtgg ggagaaagcc gatccgcgct gcaaaaacgg
     4621 gaactggacc gcgctgccgg tcctgccctt cccattccgg atgacctgcc gtcccgggag
     4681 ctggtcggca cgacgcgcca aatccatcag ctcattgaag cttccggaaa tccggcacgt
     4741 tttgaatcct acacggaaac ggttcccgcg gcgggagctt ccctgcgcat ggtcgccata
     4801 ccgggaggaa cgttcctcat ggggagtccc gcggaagagc cgcaccggaa accggacgaa
     4861 ggtccgcagc ataaagtgag catctctccc ttctggatct cggaaacgga aatcccctgg
     4921 gaactttata cggccttcat ggaaaacggg cgtccgcgcg ccaaggacgg ccagcttctg
     4981 gaggaacagc cggatgacga actgtgggac tccgtcacgc agcctaccgc cccctacgcc
     5041 gccatgaacc tgggcatggg ccacggctat gaacacggcc tgcccgccat ctccatgtcc
     5101 caccacgccg ccagcaaatt ctgcgaatgg ctgagcgccc agaccgggca ttactaccgc
     5161 ctgcccacgg aggcggaatg ggaatacgcc tgccgggccg gttccgccgg cgcctattct
     5221 tacggaaacg gggaagcctc tctggaccag tacgcctggt actggaacaa ttccaatgac
     5281 cgctaccaga aaacaggctc taaaaaacca aataagtggg gactccggga catgcacgga
     5341 aatgtggcgg aatgggtttt ggactcttac gttccggatg cctacggcaa acggagcggc
     5401 ttgcccacga aagaccccct ggtcatcatc cccggcgccc ctcacatcgt tcgcggcggt
     5461 tcgtgggaag acgacccgga cagcctgaga agcgctgcgc gccgcgccag cacccccgcc
     5521 tggaaccgtc aggatcctca aaaccctaaa agcatctggt acctgacgga cggaggcatg
     5581 atcgggttcc gcgtggtgcg ccccatgaac attccggaca ttatgacgat gcaccgcctc
     5641 tggaatttct ccaaggggga gccgtaaaga acaatctttc atgaccattg cattaagaac
     5701 ggaacaatcc tcagaccatg ccgaaacgga acatgtcacg agagaagcgt tctgaaacta
     5761 tttcgtcccc ggctgcaatg aacattacct gctccatatc atgcgcgtca gtccttcctt
     5821 catcccggag caggatgcag tcgccatcca cggcagccgc atcgtcggga aacatcgttg
     5881 atgcaacgtc cgtcatcagg gcagacgatg gaaaagaata tgaagtgctg ggcatggggc
     5941 ccattgccgt tcttccggaa taccagcgcc ggggaatagg acggcggatg atcggctaca
     6001 ccaggaaccg ggcgcgtgaa atgggcttcc gtgccatttt cctgtacggc gacccggact
     6061 actcttcaca ctgtggattc gttcccgcgg aaacgctggg catcagaacg gcggataata
     6121 ggtatgcggc ggccctccag gtctgtgcgc tgcaaagggg ttccctatcc ggcctgaaag
     6181 gccgctatgt ggaagctgcc gtgtaccata tggacgaaaa gcgcgctgcc gaatttgacc
     6241 ggcattttcc ggtaaagaaa aagctttccg gtattgcgtc tcaaaaacgt ttccagcaaa
     6301 ttgccgccat gcggagaaaa ccggatacgg ccccctgccc ccggaaatcc cgtaccttcc
     6361 ggagggcatg aatcccgcat gcggatgagt aattcttcct ctctggatat aaaaaacaag
     6421 agctgttccg caagaacagc tctcatccgc cgatttttcg ccatcaggaa gctcaagccc
     6481 tgcggcggcg catcatcagc gcggccagtc ccagcaggcc cagggaaacc gtggctggtt
     6541 ccggcaccat ttcccctcgg atttccgtga aaatcggaga taataagctg aaagtattgg
     6601 ttccgttggc tcccgtaata acaacagaat caccaggcgc tccctcggcg tcataatggc
     6661 cgcggatgcc gggagcagtc aatccgccgc tgatcgttac ggtatctcct tccgtgttag
     6721 cagtaggggc ggctgtcccc cccgcagcat ataaatacgt tttagacgta tcctgcatca
     6781 agcccatcac ggactggctc acggccagga agcggtatgt caatgccgcg tcaagaagca
     6841 ggggagaacc atccagggaa gaaaaactga acgtcagatt aatccctgct gcagtagttc
     6901 ccgtattggt gctccagccg atgaccgaat tgtcggagcc attcagcacc aggaagccgt
     6961 aagtgacatt agcgcccaaa ttgttggcgg ctccgcgcag cgtaaaactg tccagtctga
     7021 tctctccgga cagggaggag ggagaagagg aatcggaagg agccagggaa gaagacccca
     7081 ggctaagata aaacccatgg atggtactat tgtaattatc cgtaccggga gtgtaataat
     7141 taaaaacggt cgctgcctcc gaggaaacag caaagcttcc catcgcgatt aaaagtgtca
     7201 gtgttttctt catatttatt attccttttg gatggcaact tgtagcgaat tccaaattcg
     7261 ttattcaagc acaagtacat acattgaatc ttgcatcatt ttattaagat actgaccatg
     7321 aataaattat tatccaccct gattctttcg gccggcatga gcctaagcgc taccgcggct
     7381 acctctctgc tggatagctc catcgtggga tattcggact ttgcctccca aacggcggat
     7441 ttcggcaccc tgaaagattc cgtttccatc acgtctgacg acagcaatct gacgttatcc
     7501 gggataacct tcaacggata cggtgccaac aaccgcgacg ttatgtctgt gacgatggtt
     7561 cttgacctgt ccaaaatcaa cactccggac gcctataccg ctctgtttaa cgccaaaaac
     7621 agcagtgtaa gctggggcgt gggcctgaac acggaccgga aactccaggg attatggaac
     7681 aacacctcat acaacgggcc cgtcgttgac accccgctgg gcacggaagg ttccctgacc
     7741 atttccgtag tcaccggaga tcttggcacc cgcatctatt ttggcgacag cgctacgtac
     7801 tattccaaca gcggcctgaa attcggcaac cagcaaatta atcagattct catggacgca
     7861 ggactggctg aatccatcga acagctctac atccacgact cccttctttc ccaggatcag
     7921 atcggtcagc tgatgagtga aatcgccagc gttccggaac ccgccacggc ctccctgggc
     7981 ctgctgggac tggccgcgct gatgatgcgc cgccgcaggg cataagcctg taccgtccgc
     8041 ctccctatat tcaaaggccg gctcacaaaa tcgtgagtcg gccttttcct tatcctctca
     8101 aacatctgcc gaaaaaaaca gggggaagaa gcttccattt gctgcggcaa cctcacggcc
     8161 agcacttgac ggggaaatgg cattcagtct cccccgggag ggtcatttca agagcttccg
     8221 gccccgcccc acttccgtac acgccctttt ttcccatgcc ggaacagccg gagccgggcc
     8281 ctgcaaagtc cggattccct ctgcatccgg aacaggccat cctctcagca attcatttcc
     8341 ccgcatgatc cgagtcaccg cgcttccgtc cgctggaagc gacctctcgc cctgaaacag
     8401 ggggaaagag gggaaatgac tgagctttaa ccttcattcc ccgttcctca tgaaccttca
     8461 aaaacagcag ctgttgctgc gtctgtgccg gtatttcaaa agcagaaaag gagaaccgcg
     8521 ttttttcaac aaacggaata tatgccttct ggccgccgcc agcgcctaca tcctgactcc
     8581 cgacgaattc ctgtttgacg gaatcggcaa gctgggcctt ctagatgacg cggcggtcat
     8641 cctgggagcc gttctcaccg ttcttttttc cggatggaga ctaacggccc gcacccaccg
     8701 caggcggaat tagcgggacg acactttccg gaacttcgga gactgtccca tgaatgtctc
     8761 cggattttcc aagagaagac gttccgtttc ctgccgggaa aaaccgcgcc tgcgtagctc
     8821 gcaggccaga gccgtcagcg ccaggggatc ggaatccccc cagtctgccg cggaattggc
     8881 ccagacacgg tccattccgt acaattccag aatatccgcc gcccgcttgg gattcagctt
     8941 gctggtggga taaagggtca gtccggccca gtagccggcc tccttcacca gcgggaaggt
     9001 atgttcctca cagtgatcca ccaacacgcg gcaaggatcc agatccggac ggtttttcag
     9061 ggcggaaaga atcattacgg tccccttcag cttgtcttcc aaatggggag tgtgaatcag
     9121 cacaagctgg ttgaggcgca ccgccagatc cagatgctct tcaaaaatgg tcatttcatg
     9181 ggaagtattc cggttcagcc ctatttcccc gatgccaagg acattgggcc ggtcaataaa
     9241 ctccggaatg agtttcatca cctcccgtgc aaaggccacg tcttgcgcct ctttgggatt
     9301 gatgcacaac catgtgtaat ggtccatgcc gaacttggcc gccctggcgg gttcgcattc
     9361 cgtaagctgt acgaaataat cccggaaacc gtccacggac gaacggtcat aaccggccca
     9421 gaacgccggc tcccctaccg ccaggcagcc tgcctgcgcc atggcccggt attcgtccgt
     9481 ggtgcggcac accatatgta tatgaggttc tatgaaagcc atcattctta tttgctgagg
     9541 ttcggagctc cgcatgccgc tttggccgcg gcggtttccg gcacggcgtc atccctgtag
     9601 gaaagggctt ccagaatggc ccggacgcgt ccggggccgg atgcggacaa aaggggaaga
     9661 acctccatca gggcacggta gcggaaatcc gcctctcctt ccccgcggtc cacccggtcc
     9721 agaaatgcgg ccacatccag aacgccggcg cgcgccgctg cgaaatccgc gtccagcacc
     9781 tcttttttac tccttttcac gcacagacga tacgcctgtg cggaaagcct cgtcaagccg
     9841 gaacaggtaa caaaataata actattccaa actgataaac agcaacgcct ttccccggct
     9901 tttcaaaaat ccgaaaagcg ccggaaattc aagaagaggc ttgccatccg ggcttgaacc
     9961 gggcatcctg tgaggacgca tttatttcat tagagcgcct atgaatgcac tagtaaaaac
    10021 catatgtaca ttcgtgacat cctccatcgg ccgcaaaatc attgtggctc tgacggggtt
    10081 atgtttggtc ttgttccttg cgggacacct ggcaggcaac cttctcatct tcggaggccc
    10141 tgaatggatc aacacctacg cccacggcct gcactccatg ccggaagcag ccctctgggg
    10201 cattcgcgcg gggcttgggg tgatcttcat catccatgtc tggctgacca tccagctgaa
    10261 gctggaaaac catgcggccc gcgaacccta tgtgttcaag aacaccatca aggcgacgct
    10321 ctcctcccgc tacatgattt acaccggcct gaccgtcctg gtgttcctgg tctaccacct
    10381 gtaccaatac accctgcgcg tgggatacga ccccgcccag ttcaccacct tcatttccga
    10441 cggtacggtg gagacctttg acgtgtacaa aatgatcgtg accggattct ccaacgtatg
    10501 gtgctccgcc ttctacatcc tggccgttct gatgctgttc agccatctgc gccacggggt
    10561 acagtccatc ttccagactg tgggcgttga ttcccgcaaa atccggccct tctacaattt
    10621 tatcgccatc gcctacggcg cgattatctg cctgggcttc atctccgtgc cggtctcggt
    10681 tcttctgggc atcatcaaat aaccatcaac tcctctcaaa gccatgatta attttcccgt
    10741 aagcgactgg atgccggatg ccaaaattcc ctccggccct attcaggaca aatggtccaa
    10801 gtacaagctt gaatccaaac tgatcaatcc gaacaacaag cgcaagtaca cggtgcttgt
    10861 ggtaggttcc ggcctggctg gcgcctccgc tgccgccacg cttgccgaac ttggctacaa
    10921 cgtcaaatgc ttctgctatc aggacagccc ccgccgcgcc cactccattg cggcccaggg
    10981 cggcatcaac gcggccaaga actaccagaa cgacggtgac tccgtttacc gcctgtttta
    11041 cgacaccgtc aagggcggcg acttccgcgc ccgtgaagcc aacgtttacc gcctggcgga
    11101 agtctcctcc aacatcattg accagtgcgt ggcccagggc gttcccttcg gccgtgaata
    11161 cggcggcctc ctggataacc gctccttcgg cggcgcccag cttaagcgta ccttctacgc
    11221 acgcggacag acgggccagc agctcctgct gggtgcctac caggctttgg aaaaggaagt
    11281 ggccaaggga cacattgaaa tgttctcccg ccatgaaatg atggacctgg tgctggtgga
    11341 cggagaagcc aagggcatcg tcacccgcaa tctggtcacc ggtgaaatca agtcctacgc
    11401 aggggatacc gtcctgctct gcacgggcgg ctacggcaac gtgttcttcc tgtccaccaa
    11461 cgcgatgggc tgcaacgtca ccgccgccta caaggcctac aagcgcggcg ctttcttcgc
    11521 caacccctgc ttcacgcaaa ttcaccccac ctgcattccg gtcaagggcg actaccagtc
    11581 caagctgacg ctgatgtcgg aatccctccg caacagcggc cgcatctggg tgcccaagtc
    11641 ccgtgaaacc gcggaaaaaa tccgcaaaaa ggaaatcaag ccttccgatg ttcccgaaga
    11701 agaacgggac tactacctgg aacgcaaata tccctccttc ggcaacctgg ctccgcgcga
    11761 catttcctcc cgcgccgcca aggaagcctg cgacgacggc cgcggcgtgg ccatcaccgg
    11821 caagggagtc ttcctggact ttgcggatga aatcaagcgc atgggccgcg aatggattga
    11881 cggccagtac ggcaacctgt ttgacatgta cgaagaaatc acggacgacg acccccatga
    11941 aacgcccatg atgatctacc ccgcctccca ctacaccatg ggcggcctgt gggtggatta
    12001 caacctcatg tccaacgtga aggggctgca cgtcctcggt gaagccaatt tctccgacca
    12061 cggcgccaac cgcctgggag cctccgccct gatgcagggc ctgtctgacg ggtacttcgt
    12121 catcccagcc acgcttcccg cctacctgac gaccaccaag ccgggcgccg tcaccaccgc
    12181 ctccccggaa ttcaaggccg cggaagacga ggtgaaggaa cgcatcaaca aactcctgaa
    12241 cgtgaaaggc accaagacgg tggactcctt ccaccgggaa ctgggcctca tcatgtggga
    12301 agactgcggc atggcccgca cggaagaaag cctgacccac gccattgaac gcattcccca
    12361 gctccgcaag gaattctggg aaaacgtgcg cgtaaccggc acggcggacg gcatcaacgc
    12421 ggaactggaa aaagcctgcc gcgtggctga cttcctagaa ttcgcccagc tgctctgcta
    12481 tgacgccctg aaccgtcagg aatcctgcgg cgcgcacttc cgcgtggaat accagctgcc
    12541 ggacggcgaa gccaagcgca acgacgatga atacgcctac gtagccgcct gggaatacac
    12601 cggcgtggac agcctgcctg ttctccacaa ggaaccgctg accttcgaga acgtgcacct
    12661 tgccatccgc agctacaagt aaagatagcc aatacattaa cacttaaaag aaagattata
    12721 acatggctaa aacactcaat ctcactctca aggtctggcg ccaggaaaac cgtgacgcca
    12781 agggccgcat tgagacctat gccgccaagg acattccggt ggatgcctcc ttcctggaaa
    12841 tgctggacat cgtcaatgaa ggtctggtca aggaaggcaa ggaacccatc cattttgacc
    12901 acgactgccg ggaaggcatc tgcggcatgt gctccctgac catcaacggc attccccacg
    12961 ggccggaacg ccaggtaacc acctgccagc ttcacatgcg caagttcaag gacggcgaca
    13021 ccgtctggat cgaacccttc cgcgcgaagg ctttcccgat cctgcgggac ctgatggtgg
    13081 accgttccgc cctggaccgc atcatcgccg ccggcggcta cattgacgtg cgcaccggct
    13141 ccgcgccgaa cgccaacaac atcgccgtgg aaaaagtgaa ggcggacgcc gcctttgacg
    13201 ccgccgcctg catcggctgc ggcgcctgcg tggcctcctg caaaaacgcc tccgccatgc
    13261 tgttcacgtc cgccaaaatc gcccatctca atctgctgcc gcagggccag ccggaacgct
    13321 ccaagcgcgt cctggccatg atgaagcaga tggaagcgga aggcttcggc aactgcacga
    13381 accaatacga atgcgaagcc gcctgcccga aaggcatcag cgtggacaac atcgcccgcc
    13441 tcaaccgcga cttcatgcgg gccaatgcca aggaaggcct ctgcttctaa agaggactcc
    13501 ttcttaagac gctctacaaa aactcccggc ggcctcggct gtcgggagtt tttttattac
    13561 cgggtttcct tgagccagga ataaaatacc agatagcctc ttccgggaaa tttgacagtg
    13621 gccaggaaga gaggccatct atcagggaca ttttctaaca aacagacaac attgatgtct
    13681 attaagggaa tgcactgaac gt
//
