LOCUS       c00030_gnlPro..        15599 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BKGDMMDK_30.
ACCESSION   c00030_gnlPro..
VERSION     c00030_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 07:55:54
            Original ID  :: gnl|Prokka|BKGDMMDK_30
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15599
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15599
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2020:5599](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(2021..5599)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..15599
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15599
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             2..601
                     /locus_tag="ctg30_1"
                     /transl_table=11
                     /translation="VLDKYAPEFKIVSAVNRPTAMTRDVYDVSPVIDHAGTVTGDLLAQ
                     RKKEGKKTTFYVCVHPKKPNTFTISPLAEAEWLPLFAAANHLDGFLRWAYNSWNRNPFE
                     KTDFGNWPAGDCYLVYPGNLSSLRFEKLRDGLEEFEKVNILRARAAKNPKAKAAVARMD
                     EELSKLFTVEKSRGDSHEEDVRKAREIIRKTTEISR"
     CDS             complement(683..1003)
                     /locus_tag="ctg30_2"
                     /transl_table=11
                     /translation="MTYYNSSCPVETTLQLISSRWKVLILRDLLEGTRRFGELRKSIGP
                     VTQKVLTANLRSMEKDGLLTRKVYAEVPPRVEYTLTELGRSLRPVLASMAEWGSKYQRE
                     NR"
     CDS             1128..1295
                     /locus_tag="ctg30_3"
                     /transl_table=11
                     /translation="MNKIIIANYRETEPQVISREGNSFAVKPVIREADAGKCAASFVEV
                     EPGRSTIIMK"
     CDS             1238..1555
                     /locus_tag="ctg30_4"
                     /transl_table=11
                     /translation="MCGQFRGSGAGAVYHYHEVNEEVFYIIRGHAVVRTPEGEKNLKEG
                     DAIAFPASPEGAHVIRNGSATEKLVYLDVGTRLTPDVVHFPDTASGMVYSSSGVHHFRE
                     S"
     CDS             complement(2021..5599)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_5"
                     /sec_met_domain="PFOR_II (E-value: 6.4e-17, bitscore: 55.4,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 4.9e-78, bitscore: 255.6,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 1.8e-31, bitscore: 103.1,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.8e-11, bitscore:
                     36.6, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 1.2e-12, bitscore: 42.3,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 1.2e-09, bitscore: 31.5,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.1e-05, bitscore: 17.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 3.3e-25, bitscore: 81.3,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDQTTVTYSTIDANEAVASVAYRFSEVIAIYPITPSSPMGESAE
                     SWAAVNRKNLWGTVPSVVEMQSEGGAAGTVHGALQTGALATTFTASQGLLLMIPNMFKI
                     AGELTPAVFHVAARSLAYQALSIFGDHSDVMSARSCGWAMLCGSSTQEAADFAAISHAA
                     TLESRIPFINFFDGFRTSHEIGKIADITDDTLNGMIKQEWLDSFRERALTPDAPVLRGT
                     AQNPDVYFQGRETVNRFYEATPAIVQNAMDKFAELTGRSYHLVDYTGAPDAERVIILMG
                     SGAEAVEETVEAMMTRENAKVGVLKVRLFRPFPAAELVKALPATVRKIAVLDRTKEPGS
                     QGEPLHQDIIQALFDAQANGTLPFTNGMPKVVGGRYGLSSKEFTPAMVKGVYDNLALDT
                     PKNHFTIGINDDVLGTSLPYDEDYSTEADDVTRAMFFGLGSDGTVGANKDAIKIIGQHT
                     NLYVQGYFVYDSKKSGSSTISHLRFGPRPIKSTYLITKANFLALHQPSLLDLFDFLKNA
                     ANGATFLMNSPHPADKLWDTLPARMQQQILDKNIKLYTIDAFAVARKTGMGGRINMIMQ
                     TCFFKLASVIPADEAIGYIKKAIAKTYAKKGQEVVDKNIAAVDATLENLHQVDTTGKTV
                     NGHAIPPAMSPDAPDYVQNVLGKMMCGEGDSIPVSQMPVDGTFPNGTSQYEKRNLALDL
                     PEWDPTLCIQCGKCTAVCPHAVIRSKFFSPDALANAPEGFECLDAKHPDWKGEKFVIQI
                     SPNDCTGCTLCADVCPAKSKTDPTHKALTMVPAGKIHDKEEANWNFFLSLPDVDRTKVR
                     TDNIRSMQVLRPLFEFSGACAGCGETPYVKMLSQLFGNRLVVANATGCSSIYGGNLPTT
                     PWSHDSEGRGPAWANSLFEDNAEFGLGFRVSLDKQMEHAIELLHEAAGAVGQELVDRIL
                     ANPQKDEADIAQQRENIEELKKKIAGKPEYARLLTLADKLVRKSVWILGGDGWAYDIGY
                     GGLDHILASGRNVKVLVMDTEVYSNTGGQCSKSTPRAAVAKFATTGKPGVKKDLGLMAM
                     TYGNVYVASVALGAKDEHTLKAFVEAEAYDGPALIIAYSHCISHGINMAKGLQQQKAWV
                     DSGRVLLYRYNPDLARQGKNPLIVEGKGPKGDLRDVLLSENRFKLLAKTNKEGFEKLLE
                     EAQKDVWHRWNLYQSIAGMGADKPAE"
     CDS             5945..7426
                     /locus_tag="ctg30_6"
                     /transl_table=11
                     /translation="MSEQQQAHPTTTESELIAVRRDKLAKIRELGIDPYGARFDVTTTP
                     AGLKADFQEDKQVAVAGRLLAIRDMGKSQFFVIGDVRGKIQGFLHKNEVDETTWKLWKL
                     LDRGDWVGIRGTTFLTRTGEPTVKVSGLTILSKSLRPLPDKWHGLADKEVTYRKRHLDL
                     ISNEESASLFVTRSLMIAEIRRFLQERGYLEVETPMLQDVAGGAAAKPFETYHNALDMP
                     LTLRIAPELFLKRLMVGGFTKIFELNRSFRNEGIDRRHNPEFTMLEAYCACGDFETMAN
                     MVEELICHLAEKFCGGLQIDHKDAEGNVLYTIDLSRPWKRADYQDLIRGVAGEDWFDIS
                     PEVRRARCEELGVEISPDMKDVDVSQQVYEKLVEEKTMNPCFVTHVAKDLVPLAKLNRE
                     NPDVVDVYELVINGQEISPGYSELNDPDVQKERLEHQAAGETQRVDYDFIETLEYGMPS
                     AGGIGIGIDRVVMMLTGASSIRDVLLFPQLKRKDS"
     CDS             7444..8229
                     /locus_tag="ctg30_7"
                     /transl_table=11
                     /translation="MAPRTPDILDCASAQWIGKRREQEDVVKSLPAAGGMLGIVCDGMG
                     GHLRGDCASCVVAQEFAAVFAESGIEDIPERLTAALHAANRALAAIQKEPEESGTTLLA
                     VFIRDHFLWWISVGDSPLYLWSGADSFRMDRLNEDHSMRPIADCLYRKGKMSLQGALRQ
                     RCILRSAVMGGPMELVDISAMPLLLHPGDAVLACSDGLQVWSELLREPSFLALQKARDC
                     SSRELVGIIMEQVKDMLEPQQDNASVWAAVMRKPCEGGK"
     CDS             8482..9126
                     /locus_tag="ctg30_8"
                     /transl_table=11
                     /translation="MIAWIVFYYLIGAIPFGYLAGRIRGIDLRQQGSRNIGATNAWRVL
                     GWKWGLSVFILDFLKGFIPVFGALNWLPFLTGDAGGWDFNVLVVLSCFAVILGHTYTCF
                     LGFRGGKGVATTAGVLFALNPVVACVALASWLVVMGISGIVSLASLVAAVVMIAAGWWI
                     YPLCQDGDVSPQILYVAFFTVVGALVILKHRSNIARLLNGTEHSFYSKKSK"
     CDS             9131..10138
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_Gly3P_dh_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_9"
                     /sec_met_domain="NAD_Gly3P_dh_N (E-value: 2.6e-42,
                     bitscore: 138.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRLHKIAVIGAGSWGTALSMVLATRECEVVLWTPEEAQARQLAE
                     TRRSPVLSKTALPLAPNIHPTCDLGQVKDAELIVVVVPSVAMRSVAQRLRSLPVQPDAV
                     IVSCTKGIEQGTHKRMTEILQEYLPSNPIGVLSGPNHAEDICLGLPSASLIGFEDPKYA
                     DWVQQIFASKTFRVYSATDIIGMQLGGTIKNVFAIGAGLCEGLNLGDNAQAALLTRGLA
                     EMTRIGVASGGRRETFMGLSGVGDLIVTCYSRHSRNQTVGRRLAEGKSLQEILDTLGMV
                     AEGVPNTLSVYEIARKLEVRTPLIDAVYSVLYESKPPMEALAELMTRDPRPELD"
     CDS             10196..10630
                     /locus_tag="ctg30_10"
                     /transl_table=11
                     /translation="MKRAIISALFAAGVVGVASADIQAPPASEYTPTRKLGRAIANLIY
                     SVEEIPLGIINWTSREGDYAGFSVGIVDGTATMFERMGYGIYELVTFWAPTYKCTYKPP
                     YQGRCGMSGLKEYNPNGGLSEFPAELSFQSYYKYSRQQRD"
     CDS             10733..10984
                     /locus_tag="ctg30_11"
                     /transl_table=11
                     /translation="MHEIAAALDKVTDEPGAAAAVETVKKVHKKLLDIGKRQLELPGAT
                     LQEQAQVSAQITEAQKISGELIKSLSRLKKEEPKLWRK"
     CDS             10972..11301
                     /locus_tag="ctg30_12"
                     /transl_table=11
                     /translation="VEEVKKLNDSLARVRDEETGKAAVEQIGRYRAAMLDVARKQAALP
                     PLTRNQQAKLMGVQQQLVEMMQPIVKHVTAIMLSPDASRNLKEALNSLSELPKEVQKIR
                     EEAAK"
     CDS             11373..12434
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_13"
                     /sec_met_domain="Radical_SAM (E-value: 2.7e-22, bitscore:
                     73.5, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPVFSETDLNERPFLVFWEVTRACALACRHCRAVAQPRPHPDEL
                     THEEALRLIDQLAELRPPMLVLTGGDPVMRPDILELVRAASGKGLHVALSPAATARLLH
                     TDFHALKEAGVQSMSLSLDGAHESTHDAFRGVPHTYERTLRAAEMAKEAGMHLQINTTI
                     TRSTLGEFDDFVELVKKMKPGMWSVFLLVPTGRAAMDEMPAAEEVEAVWKKLSRISHEV
                     SFGVKTTEGHHYRRVALQEARAQGSKPARRAIPTRDGKGIMFISHTGEIQPSGFLPITA
                     GNVRTDDPGEIYRTHPLFLKLRDDNALQGKCGRCEYRTICGGSRSRAYAVYGDMMAEDN
                     LCPYQPRLSQHHD"
     CDS             12427..13674
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_14"
                     /sec_met_domain="Radical_SAM (E-value: 7.4e-27, bitscore:
                     88.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINITRLWTGAEQPADHLRYGQGHGHGRFAGGAVESCAPASSRAR
                     KPIVVWNITRTCNLKCVHCYADASARKFKGELDWDQCCAVIDDLADYKVNALLFSGGEP
                     LAHPRFMELLERATGKGLKVTISTNGTRITPEAAARFKELGVAYVGISLDGIGAVHDKF
                     RGVEGSFEQAVRGFRLCSEVGQKTGLRLTLTRNNVQCMGQILDFIDANDIQRVCFYHLV
                     PTGRGVEVQTLTQEEARNAMDTLIARVEEWKAEGKNREVLTVTQPADGIYLLLRQLREG
                     SPLAKETLGLLQWNGGGANSSGRGIANIDTQGAVHPDQFWQSVTLGNVKSDRFSDLWDA
                     RAGTAAEMLPELRGSDDPLERQKKIEGRCGRCVHFALCGGGFRTRAAFANGHWYGSDPG
                     CYLTEEEISTPLPEIK"
     CDS             13923..15224
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cys_Met_Meta_PP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_15"
                     /sec_met_domain="Cys_Met_Meta_PP (E-value: 1.5e-135,
                     bitscore: 445.1, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRMMNQELRPETLCVQAGWAPKKGEPRVLPIYQSTTFKYETSEQ
                     MAKLFDLEEAGFFYTRLQNPTNEAVARKIAELEGGVAAILTSSGQAASFFAIFNICEAG
                     DHIVSASAIYGGTYNLFAVTFRKMGIEVTFVDQDAPAEEIAKAFRPNTKAFFAETISNP
                     TLCVLDIRKMADIAHAHGVPLIVDNTFATPINCRPFEWGADIVTHSTTKYMDGHAAAVG
                     GVIVDSGNFDWEAHKDKFPGLTEPDPSYHGLSYSKSFGKGAYITKATVQLMRDLGSIQS
                     PQNAFLLNLGLETLHLRVPRHCENAQKVAEFLQGQEDVAWINYPGLSSNEYYELAQKQF
                     RGGQSCGVVTFGIKGGRERSIKFMDSLKLAAIVTHVADSRTCVLHPASHTHRQLTDEQL
                     MEAGVRPDLIRFSVGTEAAEDIIADLKQALEAIR"
ORIGIN
        1 tgtgctggac aagtatgccc cggaattcaa aatcgtttcc gccgtcaatc ggcctacggc
       61 catgacccgg gacgtttatg acgtctctcc tgtaattgac catgcaggca cggtcacggg
      121 cgatctgctg gcgcagcgta aaaaggaggg aaaaaagacg acgttctatg tctgtgtcca
      181 tcccaaaaag cccaacacct tcactatttc cccgctggcg gaggcggaat ggcttcccct
      241 ctttgccgcc gccaatcatt tggacggctt tttgagatgg gcttataatt cctggaaccg
      301 taatccgttt gaaaagaccg atttcgggaa ctggcccgcg ggagactgct accttgttta
      361 tcccggcaat ctcagttccc tgcggtttga aaaactccgg gacggactgg aggaatttga
      421 aaaggtcaat atcctgcgcg cccgcgccgc aaaaaatcct aaggcgaaag ctgccgtagc
      481 ccgcatggat gaagagcttt ccaagctctt taccgtggaa aaaagccgcg gggattccca
      541 tgaggaagac gtgcggaaag cccgcgaaat tatccgtaaa acgacggaaa tttcccgctg
      601 acctttcttg cgggaaaaag ggaaactgct gtatttccat gtctttccgg aggttcggtt
      661 aagctccgga aaggggggag gatcagcggt tttctctttg gtatttcgat ccccattccg
      721 ccatggaggc caggacgggg cgcagactgc gccccagttc cgtaagagta tattccacgc
      781 gcggaggtac ttccgcatac acctttcgcg taagcaggcc gtccttttcc atagaacgca
      841 ggttcgcagt cagaactttc tgcgtcacag gcccaatgga tttgcggagt tctccaaacc
      901 gccgggtgcc ttcgagcaga tcgcggagga tgagcacttt ccagcgggag gaaatcagtt
      961 ggagagtagt ttcaacaggg catgatgaat tatagtaagt catttatttt aagcaatagt
     1021 ttctttcagg aatccagggt actattttct gcctacttta caaaaagaat gttgccgcct
     1081 attttaataa gtgcctgccg ttacggcaag catgaacaga taatgccatg aacaagatca
     1141 tcattgccaa ttacagggag acggagcctc aggttatcag ccgggagggt aattcctttg
     1201 cggtaaagcc cgtcatccgg gaagcggatg ccggaaaatg tgcggccagt ttcgtggaag
     1261 tggagccggg gcggtctacc attatcatga agtgaatgaa gaggtatttt acatcatcag
     1321 gggccatgcc gttgtgcgta cgcctgaggg tgaaaagaat ttaaaagagg gggatgcgat
     1381 tgcattccct gccagcccgg agggagcgca tgttatccgc aacggatccg ctacggagaa
     1441 gctggtctat ctggatgtgg gcactcgcct gacgcctgat gtggtgcact tcccggatac
     1501 ggcatccgga atggtatatt cctcctccgg tgtgcaccat tttcgggaat cttgaagcag
     1561 catccctgtt ttaaagcctt tttccggttt ttccaccggc gcggtccgca ggaaagcggg
     1621 ccgcgctcct ctggggagga aggtgtgagg aaacagtatt cccctggccg catgaaatgc
     1681 ccctctttgc cttggacatg gctggccgca aaggctgcgg ttcattgaag gccttcaaaa
     1741 cctccatgcg gaaattaacc cgtataaggt gatatattaa aactcggcct tgcagcaagg
     1801 tgtgcgccct tttttgtgct gcgggggaag gatgaattct ccggctttca ggaagggaaa
     1861 gtactggcgc gggaagcctg cttgcgtggc tgtatggcgg ggcggaaaag cagtcccctc
     1921 cccgaaatat tcatggtttg tttttcatga atatccggca gtaaaaaacg cccctgccgg
     1981 ataagccgga caggggcgtt gaaattaagc ggcctatacc ttattccgca ggtttgtcgg
     2041 cacccatgcc ggcaatgctt tggtacaggt tccagcggtg ccagacatcc ttctgggctt
     2101 cttcaaggag tttttcgaat ccttccttat tggtcttcgc cagaagtttg aagcggtttt
     2161 cgctgagcag tacatcgcgc agatcgccct tcgggccctt gccttccaca atcagcggat
     2221 tcttgccctg gcgggccagg tccggattat agcggtaaag caggactcgg ccggaatcca
     2281 cccatgcctt ctgctgctgc aggcccttgg ccatgttgat gccgtgggag atgcagtggg
     2341 agtaggcgat gatgagagcc gggccgtcat aggcttccgc ttccacaaag gctttcagcg
     2401 tgtgttcgtc cttggcgccg agagcgacgg aggccacgta cacgttgccg taagtcatgg
     2461 ccatgagccc cagatccttt ttcactccgg gcttgccggt cgtggcgaat ttggctactg
     2521 cggcgcgcgg ggtggatttg gagcactggc cgccggtgtt ggagtatact tccgtatcca
     2581 tgaccagcac cttcacgttc cggccgctgg ccagaatgtg gtccaggccg ccgtagccga
     2641 tgtcgtaggc ccagccgtcg ccgcccagaa tccacacgct cttgcggaca agtttatccg
     2701 caagggtcag gaggcgcgcg tattccggct tgccggcgat tttcttcttg agttcttcaa
     2761 tgttttcacg ctgctgggcg atgtctgctt catccttctg cggattagcc agtatccggt
     2821 ccaccagttc ctggcccacg gcgccggcag cttcatgaag aagctcaatg gcgtgttcca
     2881 tctgcttgtc cagggagacg cggaagccaa ggccgaattc ggcgttgtct tcaaacaggg
     2941 agttggccca ggcggggccg cgcccttcag agtcatggga ccacggggtg gtgggcaggt
     3001 tgccgccgta aatggaggag cagcccgtag cattggcgac caccaggcgg ttgccgaaga
     3061 gctgggagag catttttaca tacggggttt caccgcagcc ggcacaggcg ccggagaatt
     3121 cgaacagcgg gcgcagcacc tgcatggagc ggatgttgtc cgttcttacc ttggtgcggt
     3181 ccacgtccgg aaggctcagg aagaaattcc aattggcttc ttccttgtcg tgaatcttcc
     3241 cggccgggac catggtcagg gccttgtgcg tcggatccgt cttgctcttg gccgggcaga
     3301 cgtccgcgca gagcgtacag cccgtacagt cgttcgggga aatctggatg acgaatttct
     3361 ctcccttcca gtccggatgc ttggcatcca ggcattcaaa cccttccggg gcgtttgcaa
     3421 gagcgtcagg agagaagaat ttgctgcgga taaccgcgtg cgggcagacg gcggtacact
     3481 tgccgcactg gatgcagagg gtcggatccc attccggcag atccagggcc agattgcgct
     3541 tttcgtactg ggacgttccg ttcgggaatg tgccgtccac gggcatttgg ctgaccggga
     3601 tgctgtcgcc ttcaccgcac atcatcttgc caaggacgtt ttgtacgtaa tccggagcgt
     3661 ccggggacat ggcgggcggg atggcgtgtc cgtttacagt ttttccggtt gtgtccacct
     3721 gatgcaggtt ttccagcgtg gcgtccacgg cggcgatgtt tttgtccacc acttcctgcc
     3781 ccttcttggc gtaggttttg gcaatggcct tcttgatgta gccgatggct tcatccgcgg
     3841 gaatcacgct ggccagcttg aagaagcagg tctgcatgat catattgatg cggccgccca
     3901 tgcccgtttt gcgggccacg gcaaaagcgt caatcgtgta gagcttgatg ttcttgtcca
     3961 gaatctgctg ctgcatgcgg gcgggcagcg tgtcccagag cttgtccgcc gggtgcgggc
     4021 tgttcatcag gaaagtggcg ccgttggcgg cattcttcag gaagtcgaac agatccagca
     4081 gggaaggctg gtgcagggcc aggaagtttg ccttggtgat caggtatgtg gatttgatcg
     4141 gacggggacc gaagcgcagg tgggaaatgg tggaggaacc cgatttcttg gagtcataca
     4201 cgaagtagcc ctgcacatac aggttcgtat gctggccgat gatcttgatg gcgtccttat
     4261 tggcgcctac ggtgccgtcg gaaccgaggc cgaagaacat ggcccgcgtc acgtcgtccg
     4321 cttccgtgga ataatcttca tcatacggga ggctggtgcc cagtacgtcg tcgttgatgc
     4381 cgatggtgaa atgattcttg ggagtgtcca gagccaggtt gtcatagacg cccttgacca
     4441 tggcgggggt gaattccttg gaggagaggc cgtagcgtcc gcctaccacc ttgggcatgc
     4501 cgttggtgaa gggcagcgtg ccgttggcct gggcgtcgaa gagagcctgg atgatgtcct
     4561 ggtggagcgg ttctccctgg gagccgggtt ccttggtgcg gtccagcacg gcgatcttcc
     4621 tgaccgtagc ggggagggcc ttgacgagtt cggcggcggg gaatgggcgg aacaggcgca
     4681 ccttcagcac gcctaccttg gcgttttccc gggtcatcat ggcttctacc gtttcttcca
     4741 cagcttcagc gccggatccc atcaggataa tgacgcgttc ggcgtccgga gcgccggtgt
     4801 aatccaccag atggtaggaa cggccggtaa gttccgcgaa tttgtccatg gcgttctgga
     4861 caatagccgg agtggcttca taaaaacggt tgaccgtttc acgtccttgg aagtaaacgt
     4921 ccgggttctg ggcagtgccg cgcagaacgg gagcatcagg ggtcagggct cgttcccgga
     4981 aggaatccag ccattcctgc ttaatcatgc cgttcagggt atcgtccgtg atgtctgcaa
     5041 tcttgccgat ttcgtgggac gtgcggaacc cgtcaaagaa attaatgaaa ggaatgcggg
     5101 attccagtgt agcggcgtgg gaaatagcgg cgaagtccgc agcttcctga gtggaggagc
     5161 cgcacagcat ggcccatccg caggagcggg cgctcatcac gtcgctgtgg tcgccaaaaa
     5221 tggaaagggc ctggtaagcc agggaccggg cggctacgtg gaacacggcg ggagtcagtt
     5281 cccctgcgat tttgaacatg ttcgggatca tcagcaggag cccctgggat gcagtgaacg
     5341 tagttgcaag cgctccggtc tggagggcgc cgtgaacggt gcctgccgcg ccgccttcac
     5401 tctgcatttc caccacggag ggaacggtgc cccacaggtt cttcctgttg acagcggccc
     5461 agctttcagc tgattcaccc atcggagaag atggtgtaat ggggtaaatg gcaatgactt
     5521 cagaaaaacg ataggctacg gaggctacgg cttcgttagc gtcaatcgtg ctgtaagtta
     5581 cggttgtctg atcactcata agtctgcacg gatagtatat aattgataaa taaggtgcgt
     5641 cttaacggga acatttataa catgtctggt gccaaaggta aaagcaatta tgcgtatgtg
     5701 gggctttgcc ggccattttt taataataag accagttttg tttcaattcc tttggatatc
     5761 gtgctttatg tggttctgtc caagcttttt gcaaaacggc tgaaatactg aggcatgttc
     5821 cggcatccgg cttccggaaa agggggggga agagccttcg ggtcaaaacc ggccgccaaa
     5881 aatgtctcct ctgcctgaca atgcgctagc caaaacggaa gcaagccttt agaatccccg
     5941 cactatgtcc gaacaacagc aggcacatcc gaccacgacg gaatccgaac ttattgccgt
     6001 gcgccgcgac aagctcgcca aaatccgtga gctgggaatt gacccttacg gcgcaagatt
     6061 tgacgtgacc accactcccg ccggattgaa agccgatttc caggaagaca aacaggtagc
     6121 cgtcgccggc cgccttctgg ctattcgcga catgggcaaa tcccagtttt tcgtcattgg
     6181 ggacgtacgg ggaaaaatcc aggggttcct gcataaaaat gaggtggatg aaaccacctg
     6241 gaagctttgg aagctcctgg accgcgggga ctgggtcggc atcaggggaa ccacgttcct
     6301 gacccgtacc ggagaaccta ccgtaaaggt atccggactg accattcttt ccaaaagcct
     6361 ccgccccctg ccggacaagt ggcacggact ggcggacaag gaggtgacct accgcaagcg
     6421 ccacctggac ctcatttcca atgaggaaag cgcctccctg ttcgttacgc gctccctcat
     6481 gattgcggaa atccgccgct ttctccagga acgcggttat ctggaagtgg aaacccccat
     6541 gcttcaggat gtggccggtg gggccgccgc caagccgttt gaaacgtacc ataacgcgct
     6601 tgatatgccg ctgacgctgc gcattgcccc ggagcttttc ctcaaacgcc tgatggtggg
     6661 cggcttcacg aaaattttcg aactcaaccg cagcttccgc aatgaaggaa ttgaccgccg
     6721 ccacaacccg gaattcacca tgctggaagc ctattgcgcc tgcggtgatt ttgaaaccat
     6781 ggcgaatatg gtggaggagc tcatctgcca tctggcggaa aaattctgcg gcggccttca
     6841 gattgaccac aaggacgctg aaggcaacgt tctttacaca atcgacctca gccgtccctg
     6901 gaaacgcgcc gactaccagg acctgatccg gggcgtggcg ggggaagact ggtttgacat
     6961 ttcccccgaa gtgcgccgcg cccgctgtga agagctggga gtggaaatca gcccggatat
     7021 gaaagatgtg gatgtttccc agcaggtgta tgaaaaactg gtggaggaaa agaccatgaa
     7081 cccctgcttt gttacccacg tggccaagga cctggttccc ctggccaagc tgaaccggga
     7141 aaatccggac gtagtggatg tatatgaact ggtgatcaac gggcaggaaa tttcccccgg
     7201 ctattcggaa ttgaacgatc ctgacgtgca aaaggaacgc ctggagcacc aggctgccgg
     7261 ggagacccag cgcgtggact atgatttcat tgaaacgctg gaatacggaa tgccctccgc
     7321 aggcggcatc ggcatcggca tcgaccgcgt cgtcatgatg ctgacggggg cttcttccat
     7381 ccgtgacgtg ctgctcttcc cgcagttgaa acgtaaggac agttaatccg aaccaccggc
     7441 cgcatggctc cccgcacccc ggatattctg gactgcgctt ccgcccaatg gatcggcaaa
     7501 cgccgcgagc aggaagacgt ggttaaaagt cttcccgccg ctggcgggat gctaggcatc
     7561 gtgtgcgacg gcatgggagg gcatcttcgc ggagattgcg cctcctgtgt ggtggcgcag
     7621 gaatttgccg cggtatttgc ggaaagcggc atcgaggata tcccggaacg tttaacggcg
     7681 gctttgcatg ctgccaacag ggcgttggcc gccattcaga aggaaccgga ggaatccgga
     7741 accacattgc tggccgtctt catccgcgac catttcctgt ggtggatcag cgtgggagac
     7801 tcccccctgt atttatggag cggagcggac agctttcgca tggaccgtct gaatgaagac
     7861 cattccatga gaccgattgc ggattgcctt taccggaagg ggaaaatgtc acttcagggt
     7921 gcgcttcggc agcgttgcat tctccgttcc gccgttatgg gcggtcccat ggaactggtg
     7981 gacatcagcg ccatgcccct gctcctgcat ccgggagatg cggtgctggc atgctcggac
     8041 ggcttgcagg tttggagcga gctgttgaga gaaccttctt tcctggctct tcaaaaggcc
     8101 agggattgtt ccagcaggga gctggtgggg atcattatgg aacaggtgaa ggatatgctg
     8161 gagccccagc aggataatgc ctccgtctgg gctgccgtca tgcggaaacc ctgcgagggc
     8221 ggtaaataag cttattccgg cgaaggaagt gcgggagcat ggttctgggc gggcgggaaa
     8281 atgttcgcgc tgttcttatt gcgccttaaa cagggctttt ccgcagaccg gggcacggag
     8341 agccttgaaa atgaggatct ggaggaggct gtcaggcatg gtgttctttt acgggagcaa
     8401 cccctccgga aagaaccggg ccggaggtga tttccccatt gtcatttgac cggcggggga
     8461 ttaaaatgca ctccgcacaa catgattgcc tggatagttt tctattacct gatcggagcg
     8521 attccgttcg gctaccttgc cggcagaatc agagggattg acctgaggca gcagggttcc
     8581 cgcaacatag gcgctaccaa tgcgtggcgc gtactgggct ggaagtgggg cctttccgtt
     8641 ttcattctgg acttcttaaa ggggttcatc cctgtgttcg gcgccttgaa ctggctgccg
     8701 ttcctgacgg gggatgcggg cggctgggat ttcaatgtct tggtagttct ctcctgtttc
     8761 gctgttatac tcggtcatac ttacacttgt ttcctgggat tcaggggagg aaaaggcgta
     8821 gcgacaaccg cgggggtttt atttgccctc aatccggtgg tggcttgcgt agctctggct
     8881 tcttggctgg tggttatggg aatctccggc atcgtgtccc tggccagcct ggtggccgct
     8941 gtggtgatga tcgccgccgg atggtggatt tatccgcttt gccaggacgg ggatgtctcc
     9001 ccccagatac tttacgtcgc ctttttcacg gtggtaggcg cgctggtgat tctcaagcac
     9061 cgttccaata tcgcaaggct tctcaacgga acggagcact ccttctattc caaaaagtcc
     9121 aagtaagatg atgaatcggt tacataaaat agcagtcatt ggagccggtt cctggggcac
     9181 ggccctctcc atggttctgg cgacccggga atgtgaagtc gtcctgtgga cgccggaaga
     9241 ggctcaggcc aggcagcttg ccgaaacaag gcgcagcccc gtcctttcga aaaccgccct
     9301 tcccctggcc cccaatatcc atcctacttg cgatctgggc caggtgaagg atgcggaact
     9361 cattgtagta gtggtacctt ccgtggccat gcgttccgtg gcccagcggc tgcgcagcct
     9421 gccggtgcag ccggatgccg tcattgtctc ctgcaccaag ggcattgaac agggaaccca
     9481 taaaagaatg acggaaatcc ttcaggaata tctgccctcc aaccccatag gcgtgctttc
     9541 cggtcccaat catgcggaag atatctgcct gggccttccg tccgcctccc tgattggatt
     9601 tgaagatccg aagtatgcgg attgggtgca gcagatattt gcatccaaaa ccttccgtgt
     9661 ttattccgct acggacatta tcggcatgca gctgggcgga accattaaga acgtctttgc
     9721 catcggggcc ggcttatgcg aagggctgaa cctgggggat aacgcccagg ccgctttgct
     9781 gacccgcggc ctggcggaaa tgacgcgcat cggcgtggcc agcggaggcc gcagggaaac
     9841 cttcatgggc ctttccggag taggcgattt gattgttacc tgctattccc gccactcccg
     9901 caaccagacg gtggggcgga gactggcgga agggaagagc ctccaggaaa tcctggatac
     9961 cctgggcatg gtggcggaag gggtgcccaa cacgctatcc gtctatgaaa ttgcgcggaa
    10021 gctggaggtg aggacgcccc tgattgacgc cgtttattcc gttctttatg aatccaagcc
    10081 gccgatggaa gcgcttgcgg aactcatgac gcgggacccc cggccggaat tagattgatt
    10141 ttttgttttt ttgagttgct ttccctcgac aaattatact atataaacaa tcagtatgaa
    10201 acgtgccatc atctcagctc tttttgccgc cggcgtcgtt ggtgtcgcca gtgcggacat
    10261 tcaggctccc cccgcttccg aatatacccc cacccgcaag ctgggccgcg ccatcgccaa
    10321 ccttatttat tccgttgaag aaattccgct gggaatcatc aactggacga gccgcgaggg
    10381 agattatgcc ggtttttccg taggcattgt tgatggcacc gctaccatgt ttgaacgcat
    10441 gggctacgga atttatgaac ttgtcacctt ctgggctcct acttacaaat gcacgtacaa
    10501 gcccccttat caggggcgtt gcggcatgag cggcctcaag gaatacaatc ccaatggcgg
    10561 cctgagcgaa ttccctgcgg aactcagctt ccagagctac tacaagtatt cacgccagca
    10621 gcgcgactaa ggccgggctg ttaagatttc aaaagggctg tccgcaaaca agcggacagc
    10681 cctatttgcc caggactccc atctttccct gaccaggcag agcgttgcca gcatgcatga
    10741 aatcgcagcg gctctggaca aggtaacgga tgaacctggg gcggccgctg ctgtggaaac
    10801 ggttaaaaag gttcataaaa agctgctgga cattgggaaa agacagctgg agcttcctgg
    10861 tgccacgctt caggagcagg ctcaggtttc cgcccagata acggaagcac agaaaatttc
    10921 aggtgaattg ataaaatctc tgtcccgttt gaagaaggaa gaaccaaaac tgtggaggaa
    10981 gtaaaaaagc ttaacgactc tctggccagg gtaagggatg aagaaaccgg caaggctgct
    11041 gtggaacaga taggtcgcta ccgggcggct atgctggacg ttgccaggaa acaggccgcc
    11101 ctgccgcctc tcacccgcaa tcagcaggcc aagctgatgg gagtgcagca gcagcttgtg
    11161 gaaatgatgc agcccattgt caagcatgta acggccatca tgctttctcc ggatgcttcc
    11221 aggaacctga aggaagctct gaattccctt tccgaactgc ctaaggaagt tcaaaaaatc
    11281 cgtgaagagg cggctaagtg aactttttaa aggatgcgtc cttttgggct ggtcaaaaaa
    11341 ttataattgt tctaaattgg ctgtcctgaa aaatgcgccc ggtttttagt gaaacagatc
    11401 tcaatgaacg ccctttcctg gtcttctggg aagtgacgcg cgcttgcgcg cttgcatgca
    11461 gacattgccg cgccgtcgcc cagccgcgtc cccacccgga tgaattgact catgaggagg
    11521 cattgcgcct gattgaccag ttggcggaac tgcggcctcc catgctggtg ctgacaggcg
    11581 gagacccggt catgaggccg gatattctgg aattggtccg tgcggcttcc ggcaaggggc
    11641 tgcatgtagc attgagccct gctgctaccg cccggctgtt gcacacggat ttccatgcgt
    11701 tgaaagaagc tggggttcag agcatgtcat tgagcctgga cggtgcgcat gagagtaccc
    11761 atgacgcctt ccgcggcgtc ccccacacat atgaacggac tctccgggct gcggaaatgg
    11821 cgaaggaagc cggcatgcac ttgcaaatca acaccaccat taccaggagc acgctgggag
    11881 aatttgacga ctttgtggag ctggtgaaaa aaatgaaacc gggcatgtgg agcgtgtttc
    11941 ttctggtgcc cacaggccgc gccgccatgg atgagatgcc tgcggcggaa gaagtggaag
    12001 ccgtctggaa aaaactgagc aggataagcc atgaggtttc tttcggcgtc aaaacgacgg
    12061 aagggcacca ttatcgccgc gtggcgcttc aggaagcccg tgctcaggga agcaagcctg
    12121 ctcgccgcgc cattcccacc cgggacggca agggcattat gtttatttct cataccgggg
    12181 aaatacagcc ctccggtttt ctccccataa cggcaggaaa cgtccggacg gatgaccctg
    12241 gagaaatcta ccgcacgcac ccccttttcc tcaaactccg ggatgacaat gcgttgcagg
    12301 gcaaatgcgg acggtgtgag taccgtacca tctgcggagg gtcccggtct cgcgcttatg
    12361 ccgtttacgg agacatgatg gcggaagaca acctttgccc ttatcagccc aggctttcac
    12421 aacaccatga ttaatattac cagactttgg acaggggcgg aacagcccgc ggaccatttg
    12481 agatacggac agggccacgg gcacggtcgt tttgcagggg gcgccgtgga atcctgtgca
    12541 ccggcttcgt cccgtgcgcg caagcccatt gtggtgtgga atattacgcg tacctgcaat
    12601 ctcaaatgcg tgcattgtta tgcagacgcc tctgcccgga aatttaaggg agagctggat
    12661 tgggaccagt gttgcgcggt cattgatgat ctggcggact acaaggtgaa tgccctcctt
    12721 ttttccggag gggagccgct ggcgcatccg cgctttatgg aactgctgga acgtgccacc
    12781 ggaaaagggc tgaaggtgac catttccaca aacggcaccc gtattacgcc ggaagctgca
    12841 gcgcggttca aggaattggg cgtggcgtac gtaggcattt ccctggacgg cattggcgcc
    12901 gttcatgaca aattccgcgg tgtggaaggt tcttttgagc aggcggtgcg cggattcagg
    12961 ctttgcagtg aagtggggca aaagacaggc ctgcgcctga ctctgacccg caacaatgtg
    13021 cagtgcatgg gccagatttt ggattttatt gacgccaacg acatccagcg cgtctgtttt
    13081 taccatctgg tccccactgg ccgcggcgtg gaagtgcaga ccctgactca ggaggaagca
    13141 aggaatgcca tggatacgct gattgcccgt gtggaggaat ggaaagcgga gggaaaaaac
    13201 cgtgaagtgc tgactgtaac ccagcctgcg gacggaattt acctgcttct gcgccagctc
    13261 cgggaaggct cccctctggc gaaggaaacc ctcggcctgc ttcaatggaa tggcggaggc
    13321 gcgaacagtt ccggccgggg catcgccaat attgacacac agggcgccgt gcatccggac
    13381 cagttctggc aatccgttac tctgggcaat gtgaaaagtg accggttttc cgatttatgg
    13441 gatgccaggg ccggaactgc tgcggaaatg ttgcctgagc tgcgcggttc cgacgatcct
    13501 ctggaacggc agaagaagat agaaggccgt tgcggccgct gcgttcactt cgccctgtgc
    13561 ggcggaggct tccgcacccg tgccgcgttt gccaacggac actggtacgg gtccgatccc
    13621 ggctgctatc tgacggaaga ggaaatttcc acccctttgc cggaaatcaa gtagtgagat
    13681 gcccggcttt attcaccggg gaacggttgg ttccgggaaa gaggtatcgg aggaattgcc
    13741 gtttcattcg atcgtagggt atcccgcgcg caggtaaaac gcccctgtcc ttgcggttga
    13801 tttgccggga acaggggttt tatactggga aaaaaccggg agtgtgcttc ggcgggggca
    13861 ggggcgaatt tgtccatacg tctggttttc cctgctttac aaggcaggag gcatcgcata
    13921 gcatgccccg catgatgaat caggaattga gaccggagac cctgtgcgtg caggcgggct
    13981 gggcgcctaa aaagggcgaa ccccgcgtat tgcccattta ccagagcacg acgttcaagt
    14041 acgagaccag cgaacaaatg gcaaaattgt ttgatctgga agaagccgga ttcttttata
    14101 cacgcctcca gaaccccacc aatgaggcgg ttgccagaaa aattgccgaa ctggagggcg
    14161 gtgtggccgc cattctgacg tcttccggcc aggcggcttc cttctttgcc attttcaata
    14221 tttgcgaggc tggggatcat atcgtcagtg cttcggcgat ttacgggggc acatacaacc
    14281 tctttgccgt cacattccgg aaaatgggca ttgaagttac tttcgtggac caggacgctc
    14341 cggcggagga aatcgccaaa gcgttccgcc ccaatacgaa agctttcttt gcggagacta
    14401 tttccaatcc cacgctttgc gtgctggata tccgtaaaat ggcggatatt gcccatgcgc
    14461 acggcgttcc cctcattgtg gacaatacct ttgccacacc cattaattgc cgtccttttg
    14521 aatggggtgc ggatatcgtc acccactcca ccaccaagta catggacggc catgccgccg
    14581 ccgtgggcgg cgtgattgtg gacagcggca actttgactg ggaagcgcac aaggataaat
    14641 tcccgggttt gacggaaccg gacccctcct atcacgggct ctcctacagc aaaagcttcg
    14701 gcaagggagc ctatattacc aaggcgaccg tccagctcat gcgcgatctg ggttccatcc
    14761 aatctccgca gaatgccttt ttgctcaatt tgggtttgga aaccctccac ctgcgtgtgc
    14821 cgcggcattg tgaaaatgcg cagaaagtgg cggaattcct gcaagggcag gaagatgttg
    14881 cctggattaa ttatccgggt ctttcttcca atgagtatta tgaattggcg cagaagcaat
    14941 tccgcggtgg ccaatcttgt ggtgtggtaa ccttcggcat taagggaggc cgtgaacgtt
    15001 ccatcaagtt catggacagt ctgaagctgg ccgccatcgt gacccatgtg gcggactccc
    15061 gtacctgcgt tctccatccc gccagccata cgcaccgcca gttgacggat gagcagctca
    15121 tggaggcggg cgtacggcct gacctcatcc ggttttccgt agggacggaa gctgcggaag
    15181 acattattgc ggacctcaaa caggctttgg aagctattcg ttaaaaagtc ttcttggaaa
    15241 aagccgcctc actttgctga ggcggctttt tctttatcat taaggattgg ataaagggga
    15301 cagcggattg ttaatccgtt gtcaacataa aaagttgaaa gagcggtatt ccggcagtgg
    15361 acttcttttt tgatgcaagg gctttataga gactaatcct tgcgcctctt ccattctaac
    15421 ccattacatt atgcggtcgc tccggagtag cggggtcttc ctttgccatg gttcttggag
    15481 ggccgcagga gggggattcc gtttcttcca ttacgttttc ctgcaatact ccttcttctg
    15541 taatcagcag ttattccatg gtacttgccg tatatgattc aaccggcact ctggttgag
//
