LOCUS       c00016_gnlPro..        13485 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ANEDPODM_17.
ACCESSION   c00016_gnlPro..
VERSION     c00016_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 10:16:03
            Original ID  :: gnl|Prokka|ANEDPODM_17
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13485
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..240
                     /locus_tag="ctg16_1"
                     /transl_table=11
                     /translation="ACSAAPRFFPHGSGSLQTVADRAPELPPCPACRGCRRLQSTISGS
                     RERQNDGRRRNDEADSSGIQESGVMKEARGAALS"
     protocluster    1..13485
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[738:4228]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      739..4228
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13485
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13485
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             503..742
                     /locus_tag="ctg16_2"
                     /transl_table=11
                     /translation="MGPSLSDGACLGFVRHFQVRSPGLLGTFRCNIYFLRCATMRKQLS
                     DILFLVQGNLIMKKTPDSRCRREFLQSVLRRNLL"
     CDS             complement(739..1569)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.6; E-value: 9.2)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_3"
                     /sec_met_domain="Fer2_3 (E-value: 2.3e-23, bitscore: 74.1,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 7.5e-11, bitscore: 34.2,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.1e-06, bitscore: 19.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LPSAATSKDSQYINTQKKDYNMAKTLNLTLKVWRQENREAKGRIE
                     TYAAKDIPVDASFLEMLDIVNEGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPER
                     QVTTCQLHMRKFKDGDTVWIEPFRAKAFPILRDLMVDRSALDRIIASGGYIDVRTGSAP
                     NANNIAVEKVKADAAFDAAACIGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSK
                     RVLAMMKQMEAEGFGNCTNQYECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(1547..3505)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 177; E-value:
                     2.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_4"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.9e-54, bitscore:
                     177.0, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1e-37, bitscore:
                     120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGTQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             complement(3527..4228)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_5"
                     /sec_met_domain="SucD_FumR (E-value: 2.2e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             4429..4701
                     /locus_tag="ctg16_6"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAATRAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             4704..5519
                     /locus_tag="ctg16_7"
                     /transl_table=11
                     /translation="MMAFIEPHIHMVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSAD
                     GFRDYFVQLTECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLG
                     IGEIGLNRNTSHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLD
                     PCRVLVDHCEEHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADW
                     GDSDPLALTALACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(5553..5831)
                     /locus_tag="ctg16_8"
                     /transl_table=11
                     /translation="VGKWLSLNLYPPFPSMNLQKQQLLLRLFRYFKSRKGEPRFFNKRN
                     ICLLAAAGAYILTPDEFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(6218..6952)
                     /locus_tag="ctg16_9"
                     /transl_table=11
                     /translation="LHHFIKILTMNKLLSTLILSVGMSLSATAATSLLDSSIVGYSDFA
                     SQTADFGTLKDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPDAYTA
                     LFNAKNSSVSWGVGLNTDRKLQGLWNNTSYSGPVVDTPLGTEGSLTISVVTGDLGTRIY
                     FGDSTTYYSNSGLKFGNQQIDQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIP
                     EPATASLGLLGLAALMMRRRRA"
     CDS             7079..8227
                     /locus_tag="ctg16_10"
                     /transl_table=11
                     /translation="MKLANLLINKRLFLLDYGFQNRCKIYEMREKISATDHAALAILKK
                     TGLDVVEAAQLAHELLQASKGRGSRWKRARECIRLGEEALVARGKTVVFRKAVDEAMEA
                     RQDRRKRTRDDFRYISRRLLRFCPEIARRPVRFITPRECRACLEKSFDTLRQRHKARLV
                     LSGIFGTAVKRGWCTENPVAHVDLPRLKEHSIPVLSLEEMRRLLAAAEEYDGGACLAAV
                     GLMLYAGIRPEEVRRLDWAQINLREGMVSLRARHSKTGGARIVTIQPVLGNLLERAVAM
                     GSVSGSVCPRNWPAKWRELRRLAGWDGKEKKWPADMLRHTFASYFARHFKNLHVLQMEM
                     GHASSDLLRTRYLNMEGITEMTAAVFWGNCHAGRHAIKNGRP"
     CDS             complement(8270..9601)
                     /locus_tag="ctg16_11"
                     /transl_table=11
                     /translation="MKTYTLPVIGLMTLGASAFAAAAPSTGNSLPARDNFSACKWLGDR
                     FKWFNSERDHKNPYIQEFNVSLRMQYGLDWIDPNGEGRVMGEKEGNGHRFNDEWRRFRA
                     GFNMKFLNNFKLNNVWNIGGMDGLESYNAKTNTWDTSDLTYSLYELNLEYKGGPVTYAI
                     GKIKPRITGEYRTSSSAILTIERSMLVNQLRSETNYGFQVNNSDKKDKLGWAAGVWLNG
                     NGGTGTGTFNNRIEPAFNSRDNCFITGTLSYDTSNDVFLKKSRLWLDYAHNFTKWGDDA
                     QNKAYEKLTGYGFKSKYQGTGARDVVALTWEGSEGDFSLMTEVMAGFNVIGMKAGAENV
                     FGVTVMPSYKFTPHWEGVVRYQMAAGSNAVKWEKRYTQNSTYSGTSDCMQALYLGVNYY
                     IFECSPNMAKIMAGIEYAHSNGTDASRQKGFTGWSYNIAFRTNF"
     CDS             complement(9745..10440)
                     /locus_tag="ctg16_12"
                     /transl_table=11
                     /translation="MNHTALEDKLGYRFNNPDLLVQALTHPSTDSKPETRRAYERLEFL
                     GDAILQLAVTQYLYHHMPQSPEGELTQLRARTVSRANLGKYGFILGLDKHIALGKGEER
                     AGGRSKNSIIANTFESVFGAMSLDSNYETAKAVALRVLHEALDSAASHPKEINPKGELQ
                     AILQDILPETPSYETEEKGPRDAENRFESRVFWHGHAIGAGSGASKRKAEVAAAADALD
                     ARAWLRMTL"
     CDS             10601..11107
                     /locus_tag="ctg16_13"
                     /transl_table=11
                     /translation="MMKKIEPKEIQDNAVQLIGGDWMLVTAGSPEHFNMMTASWGGLGF
                     MWKKPVAFVVIRPQRHTFRFIEAGDELTLSFFSHEYHKALTVCGTTSGRDTDKVAASGL
                     TPYVTENGNVSFTEARLVLECRKLYAEPLNPEAFLDKSIVPEWYAAGDFHKMYIVEILN
                     VWVKE"
     CDS             complement(11162..12217)
                     /locus_tag="ctg16_14"
                     /transl_table=11
                     /translation="MISRLKLMDFRCYGSFSWQIPQQGAIILGNNARGKTSLLEAVCFL
                     LRLQSPRTARTGPLVSHGKQSFGIRGELPGQIRRILWAPDAPDLRVNGEPRKDQRSYLA
                     DSYPVVWMGNDDLSLVQAGADARRKYMDFLGSQWHPGYRLALFSYRRALKTRNYLLKHR
                     HRDKLQLDAYTRQLALHGTELRNLRAHLLALLAPHIALAYRNIGGRQEQVSIAYRASEE
                     GDLYERLCASMDRDIRYGQTQNGPHRDDLDITLNGRNAAQFASEGQQRTTAISMKLAQS
                     SLLTEETGHTPIHLIDDVFGELDPTRRIAFLQSLPADAQSLITTTHLDWLHDAPCPLPA
                     FRLEDGTLAPL"
     CDS             complement(12236..12847)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_15"
                     /sec_met_domain="Acyltransferase (E-value: 2.4e-24,
                     bitscore: 77.3, seeds: 46, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSFYWVFYTLFKSISKAFFSWKVVNREKLIEDGPVLIVSNHQSF
                     LDPPMLGISYEDGIYFFARKTLFQGIFKWALPLCQAIPIDQENPDAASLKHVIRLLKSG
                     KRVLVFPEGSRTPDGKIHDGMGGIGLILSKTKVPVQPLRISGAYEAFPIGARFPRLRPV
                     TVTVGDPIPFTPAELNAKGKDAYQHLTDKIMDAIRSLPAE"
     CDS             complement(12844..13485)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cytidylate_kin"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_16"
                     /sec_met_domain="Cytidylate_kin (E-value: 3.3e-69,
                     bitscore: 224.6, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHPAIAIDGPAASGKSTVAKLIADRLGYTFINTGAMYRAVTWYML
                     EQGINPADTAAVLESLPAVPLSFGKDGSQSVVLCGQHVLGEELTSQQVNDHVSTIAAIP
                     EVRALLVERQREYNRREPVVMEGRDIGTVVFPDTPFKYFVTASEEVRAARRAAEGLTDS
                     IAERDRKDSSRATAPLAQAPDALLVDTSDMTIDQVVRFITDNIQQKLSSR"
ORIGIN
        1 gcgtgctcgg cggccccacg gttctttcct catggatccg gatcgcttca aacggtagcg
       61 gatcgggctc cggagctgcc tccatgcccc gcctgccggg gctgccgccg gctccaaagt
      121 accatttccg gtagccggga acggcagaac gatggacgga ggaggaacga tgaggcggat
      181 tcatcaggta ttcaagagtc gggggtaatg aaggaagcga ggggggccgc cctttcctga
      241 tcgttttatc aatagtatga tctgaagtcg gtgtcgatag aattttattt gtatgttttt
      301 gattttttat aaaagatggt cattatttta cacgaaaaga taatattata attcttacgt
      361 tcagtgcatt cccttaatag acatcaatgt tgtctgtttg ttagaaaatg ttttcctctc
      421 atgctgagcc cttgacagga ggccatccct tccgggcatc agtccaattc ctgtaatcaa
      481 tgtttttctt tctcgaagaa agatggggcc gtcgctgtcg gacggggcct gcttaggttt
      541 cgtccggcat ttccaagtac ggtctcctgg attactggga accttccggt gtaacattta
      601 ttttttacgc tgcgcgacga tgaggaagca actgtctgat attttattcc tggttcaagg
      661 aaacctgata atgaaaaaaa ctcccgacag ccgatgccgc cgggagtttt tacagagcgt
      721 cttaagaagg aatcttcttt agaaacagag accttccttg gcgttggctc gcatgaagtc
      781 gcggttgagg cgggcgatgt tgtccacgct gatgcctttc gggcaggcag cttcacattc
      841 atactggttc gtgcagttgc cgaagccttc cgcttccatt tgcttcatca tggccaggac
      901 gcgcttggaa cgttccggct ggccctgcgg cagcagattg agatgggcga tcttggcgga
      961 ggtgaacagc atggcggagg cgtttttaca ggaggccacg caggcgccgc agccgatgca
     1021 ggcggccgcg tcaaaggcgg cgtccgcctt cactttttcc acggcgatgt tgttggcgtt
     1081 cggcgcggaa ccggtacgca cgtcaatata gcctccggag gcgatgatgc ggtccagggc
     1141 ggagcggtcc accatcaggt cccgcaggat tgggaaagcc ttcgcgcgga agggttcaat
     1201 ccagacggta tcgccgtcct tgaacttgcg catgtgaagc tggcaagtgg tcacctggcg
     1261 ttccggcccg tggggaatgc cgttgatggt cagggagcac atgccgcaga tgccttcccg
     1321 gcagtcgtgg tcaaaatgga tgggttcctt gccttccttg accaggcctt cattgacgat
     1381 gtccagcatt tccaggaagg aggcgtccac cggaatgtcc ttggcggcat aggtctcaat
     1441 gcggccctta gcttcccggt tttcctggcg ccagaccttg agagtgagat tgagtgtttt
     1501 agccatgtta taatctttct tttgagtgtt aatgtattgg ctatctttac ttgtagctgc
     1561 ggatggcaag gtgcacgttc tcgaaggtca gcggttcctt gtggagaaca ggcaggctgt
     1621 ccacgccagt gtattcccag gcggctacat aggcgtattc atcgtcgttg cgcttggctt
     1681 cgccgtccgg cagctggtat tccacgcgga agtgggcgcc gcaggattcc tggcggttca
     1741 gggcgtcata gcagagcagc tgggcgaatt ccaggaagtc ggccacgcgg caggcttttt
     1801 ccagttccgc gttgatgccg tccgccgtgc cggttacgcg cacgttttcc cagaattcct
     1861 tgcggagctg gggaatgcgt tcaatggcgt gggtcaggct ttcttccgtg cgggccatgc
     1921 cgcagtcttc ccacatgatg aggcccagtt cccggtggaa ggagtccacc gtcttggtgc
     1981 ccttcacatt caggagcttg ttgatgcgtt ccttcacttc gtcttccgca gccttgaatt
     2041 ccggggcggc ggtggtgacg gcaccgggct tggtggtcgt caggtaagcg ggcagcgtgg
     2101 cgggaatgac gaagtagccg tcagacaggc cctgcatcag ggcggaggct cccaggcggt
     2161 tggcgccgtg atcggagaag ttggcttcac cgaggacgtg caaccccttc acgttggaca
     2221 tgaggttgta gtccacccac aggccgccca tggtgtagtg ggaggcgggg tagatcatca
     2281 tgggcgtttc atgggggtcg tcgtccgtga tttcttcgta catgtcaaac agattgccgt
     2341 attggccgtc aatccattcg cggcccatgc gcttgatttc atccgcaaaa tccaggaaga
     2401 cgcccttgcc ggtgacggcc acgccgcggc cgtcgtcgca ggcttccttg gcggcgcggg
     2461 aggaaatgtc gcgcggagcc aggttgccga aggagggata cttgcgttcc aggtagtagt
     2521 cccgttcttc ttcgggaaca tcggaaggct tgatttcctt cttacggatt ttttctgcgg
     2581 tttcacggga cttgggcacc cagatgcggc cgctgttgcg gagggattcc gacatcagcg
     2641 tcagtttgga ctggtagtcg cctttgaccg gaatgcaggt ggggtggatt tgcgtgaagc
     2701 aggggttggc gaagaaggca ccacgcttgt aggctttgta ggcggcagtg acgttgcaac
     2761 ccatcgcgtt ggtggacagg aagaacacgt tgccgtagcc gcccgtgcag agcaggacgg
     2821 tatcccctgc gtaggatttg atttcgccgg taaccagatt gcgggtgacg atgcccttgg
     2881 cttcgccgtc caccaacacc aggtccatca tttcatggcg ggagaacatt tcaatgtgtc
     2941 ccttggccac ttccttttcc agggcctggt aggcacccag caggagctgc tggcccgtct
     3001 gtccgcgtgc gtagaaggtt cgcttgagct gggtgccgcc gaaggagcgg ttgtccagca
     3061 ggccgccgta ttcacggccg aagggaacgc cctgggccac acactggtca atgatgttgg
     3121 aggagacttc cgccagacgg tagacattgg cttcacgggc gcggaagtcg ccgcctttaa
     3181 cggtgtcgta aaacaggcgg taaacggagt cgccgtcgtt ctggtagttc ttggccgcgt
     3241 taatgccgcc ctgggccgca atggagtggg cgcggcgggg gctgtcctgg tagcagaagc
     3301 atttgacgtt gtagccaagt tcggcaagcg tggcggcagc ggaggcgcca gccaggccgg
     3361 aacctaccac aagtaccgtg tacttgcgct tgttgttcgg attgatcagt ttggactcaa
     3421 gtttgtactt ggaccatttg tcctgaatag ggccggaggg aattttggca tccggcatcc
     3481 agtcgcttac gggaaaatta atcatgactt tgagaggagt tgatggttat ttgatgatac
     3541 ccagaagaac cgagaccggc acggagatga agcccaggca gataatcgcg ccgtaggcga
     3601 tggcgataaa gttgtagaag ggccggattt tgcgggaatc gacgcccaca gtctggaaga
     3661 tggactgtac cccgtggcgc agatggctga acagcatcag aacggccagg atgtagaagg
     3721 cggagcacca tacgttggag aatccggtca cgatcatctt gtacacgtca aaggtttcca
     3781 ccgtaccgtc ggaaataaag gtggtgaact gggcggggtc gtatcccacg cgcagggtgt
     3841 actggtacag gtggtagatc aggaacacca ggacggtcaa accggtgtaa atcatgtagc
     3901 gggaggagag cgttgcctta atggtgttct tgaacacgta gggttcgcgg gccgcatggt
     3961 tttccagctt cagctggatg gtcagccaga cgtggatgat gaagatcacc gcaagccccg
     4021 cgcggattcc ccagagggct gcttccggca tggagtgcag gccgtgggcg taggtgttga
     4081 tccattcagg gcctccgaag atgagaaggt tgcctgccag gtgtcccgca aggaacaaga
     4141 ccaaacataa ccccgtcaga gccacaatga ttttgcggcc gatggaggat gtcacgaatg
     4201 tacatatggt ttttactagt gcattcatag gcgctctaat gaaataaatg cgtcttcaca
     4261 ggatgcccgg ttcaagcccg gatggcaagc ctcttcttga atttccggcg cttttcggat
     4321 ttttgaaaaa ccggggaaag aggttgctgt ttatcagttt ggaatggtta tcattttgtt
     4381 gcctgttccg gcttgacgag gctttccgca caggcgtatc gtctgtgcat gaaaagaagt
     4441 aaaaaggagg tgctggacgc ggatttcgca gcgacgcgcg ccggcgttct ggatgtggcc
     4501 gcatttctgg accgggtgga ccgcggggaa ggggaggcgg atttccgcta ccatgccctg
     4561 atggatgttc ttcccctctt gtccgcatcc ggccccggac gcgtccgggc cattctggaa
     4621 gccctttcct acagggatga caccgtgccg gaaaccgccg cagccaaagc ggcctgcgga
     4681 gccccgaacc tcagcaaata agaatgatgg ctttcataga acctcatata catatggtgt
     4741 gccgcaccac ggacgaatac cgggccatgg cgcaggccgg ctgcctggcg gtaggggaac
     4801 cggcgttctg ggccggttac gaccgttcgt ccgcggacgg tttccgggat tatttcgtac
     4861 agcttacgga atgcgaaccc gccagggcgg ccaagttcgg catggaccat tacacatggc
     4921 tgtgcatcaa tcccaaggag gcgcaggacg tggctttcgc gcgggatgtg atgaaactga
     4981 ttccggagtt cattgaccgg cccaatgtcc tcggcatcgg ggaaataggg ctgaaccgga
     5041 atacttccca tgaaatgact atttttgaag agcatctgga tctggcggtg cgcctcaacc
     5101 agcttgtgct gattcacact ccccatctgg aagacaagct taaggggacc gtaatgattc
     5161 tttccgccct gaaaaaccgt ccggatctgg acccttgccg cgtgctggtg gatcactgtg
     5221 aggaacatac cttcccgctg gtgaaggagg ccggttactg ggccgggctg accctttatc
     5281 ccaccagtaa gctgaatccc aagcgggcgg cggatattct ggaattgtac ggaatggacc
     5341 gtgtctgggc caattccgcg gcggactggg gggattccga tcccctggcg ctgacggccc
     5401 tggcctgcga gctacgcagg cgcggttttt cccggcagga aacggaacgt cttctcctgg
     5461 aaaatccgga gacattcatg ggacagtccc cgaagttccg gaaagtgtcg tcccgctaat
     5521 tccgcccgag gcgcggcgga gggtacggcc ctctagtccc cgtccgggaa aaagacggtg
     5581 aggacggcgc ccaggatgac cgccgcgtca tccagaaggc ccagcctgcc gattccgtca
     5641 aacaggaatt cgtcgggagt caggatgtag gcgccggcgg cggccagaag gcatatattc
     5701 cgtttgttga aaaaacgcgg ttctcctttt ctgcttttga aataccggaa caggcgcagt
     5761 agcagctgct gtttttgaag gttcatggac gggaacgggg gataaaggtt caagctcagc
     5821 cattttccca ctccttttcc ctgtttcggg gaaggagtct gttgccgacg gacggaaacc
     5881 gcagcgatcc ggaccgtgcg gggaaatgga ttgctgaaag gatgggctgt tccggatgct
     5941 gagggaagcc gggctttgca tgctccggtt ccggctgtcc cggcatggga aaaaggggcg
     6001 tgtacggaag tggggcgggg ccggaagctc ttgaaatgac cctcccgggg gagcctgaat
     6061 gccatttccc cgtcaagtgc tggccgtgag ggtaccgcag caaatggaag cttcttcccc
     6121 cctgtttttt ccggcagatg tttgaacgga taaggaaaag gccggctcac gattttgtga
     6181 gccggccttt gaatataggg aggcggacgg tacaggctta tgccctgcgg cggcgcatca
     6241 tcagcgcggc cagtcccagc aggcccaggg aagccgtggc gggttccggg atgctggcga
     6301 tttcactcat cagttgacca acttgttcct gggaaaggag ggagtcgtga atgtagagct
     6361 gttcgatgga ttcagccagt cctgcgtcca tgagaatctg atcaatttgc tggttgccga
     6421 atttcaggcc gctgttggaa tagtacgtag tgctgtctcc aaaatagatg cgggtgccaa
     6481 gatctccggt gactacggaa atggtcaggg aaccttccgt gcccagcggg gtgtcaacga
     6541 caggcccgct gtaggaggtg ttgttccata atccctggag tttccggtcc gtgttcaggc
     6601 ccacgcccca gcttacactg ctgtttttgg cgttaaacag agcggtatag gcgtccggag
     6661 tgttgatttt ggacaggtca agaaccatcg tcacagacat aacgtcgcgg ttgttggcac
     6721 cgtatccgtt gaaggttatc ccggataacg tcagattgct gtcgtcagac gtgatggaaa
     6781 cggaatcttt cagggtgccg aaatccgccg tttgggaggc aaagtccgaa tatcccacga
     6841 tggagctatc cagcagagag gtagccgcgg tagcgcttag gctcatgccg accgaaagaa
     6901 tcagggtgga taataattta ttcatggtca gtatcttaat aaaatgatgc aagattcaat
     6961 gtatgtactt gtgcttgaat aacgaatttg gaatccgtat aggaattcct gtgtcctctt
     7021 tgtcatcaaa ctgtctggaa gagaattgct gatatgacgg tgcggtgaaa cggcatgaat
     7081 gaagttggcg aaccttttga ttaataaacg actattttta cttgactacg gattccaaaa
     7141 ccgttgcaaa atatatgaaa tgagagagaa aatttcagca acggatcatg cggcgctggc
     7201 cattttaaaa aagacagggc tggatgtggt ggaagccgcc cagctggcgc atgaattgct
     7261 gcaggccagc aaagggcgcg gcagccgatg gaagagggca agggaatgca tccggctggg
     7321 agaggaagcc ctggttgcca gaggaaaaac ggtagtgttc aggaaagccg tggatgaggc
     7381 tatggaggct cggcaagatc gcaggaaaag aactagggat gattttcgtt atatcagccg
     7441 gcgtttgttg aggttttgtc cggaaatagc ccgaaggccc gtacgcttta tcacgccccg
     7501 ggaatgccgc gcctgtctgg aaaaatcatt tgataccctt aggcagaggc ataaggcccg
     7561 gttggtgctc agcggtattt tcggaacggc cgtgaaacgc ggatggtgca cggaaaaccc
     7621 tgtggcgcat gtggacctgc cgaggctgaa ggagcattcc attcccgtgc tgtccctgga
     7681 agaaatgcgc cggttgctgg ctgctgcgga agagtatgac ggaggggcgt gcctggccgc
     7741 ggttgggctg atgctgtatg ccggcatccg cccggaagaa gtgagaaggc tggattgggc
     7801 acagattaat ttaagggagg gaatggtttc cctgagggcg cgccacagca agacgggagg
     7861 agcccgcatt gtgacgatcc agccggtttt gggaaatctg ctggaaagag cggttgctat
     7921 gggatctgtg tcgggaagcg tatgcccgcg caactggccg gcgaagtgga gggagctgag
     7981 acggttggcc gggtgggacg ggaaggaaaa gaagtggcct gcggatatgt taaggcatac
     8041 gtttgccagt tattttgcca ggcatttcaa gaatttgcat gtattgcaga tggaaatggg
     8101 gcatgcttct tccgatttgc taagaaccag gtatttgaat atggaaggca ttacggaaat
     8161 gacggctgcc gttttttggg ggaactgcca tgcagggcgc cacgccatta aaaatggccg
     8221 cccctgaaca gaagcggcca gctgttgacg ggatgatacc gtccggcaat tagaagttgg
     8281 tgcggaaagc gatattgtag ctccatccgg taaagccttt ctgccggctg gcgtccgtgc
     8341 cgttggaatg ggcgtattcg atgcccgcca tgatcttggc catgtttggg ctgcattcga
     8401 aaatgtagta gttgacgccc aggtacaggg cctgcatgca gtcggaagtt ccggaataag
     8461 tggagttctg cgtatagcgc ttttcccatt ttacggcgtt gctgcccgcc gccatctggt
     8521 agcggaccac tccttcccag tggggggtga acttgtagga cggcatgacg gtcacgccga
     8581 agacgttttc agcccccgct ttcatgccga tgacgttgaa gccggccatg acttcggtca
     8641 tcagggagaa gtccccctcg gaaccttccc aggtcagggc taccacgtcc ctggctccgg
     8701 taccctggta tttggattta aagccgtaac cggtcagttt ttcatacgcc ttgttttggg
     8761 cgtcgtctcc ccacttggtg aaattgtggg cgtaatccag ccacagacgg cttttcttca
     8821 ggaaaacgtc gttagacgtg tcatagctca gcgtgccggt gatgaagcag ttgtcccggg
     8881 aattgaaagc gggttcaatg cggttgttga acgtgccggt tccggtgccc ccgttgccgt
     8941 tcagccagac gcctgctgcc cagccgagct tatccttttt gtcggaattg ttcacctgga
     9001 atccgtaatt ggtttccgag cggagctggt tgaccagcat ggagcgttcg atagtcagaa
     9061 tggcggagga ggatgttcgg tattccccgg tgatgcgcgg ctttattttg ccgatggcat
     9121 aggtgacggg gcctcccttg tattccagat tcagttcgta aagggagtag gtcaggtcgg
     9181 aggtgtccca tgtgttggtt tttgcattgt agctttccag gccgtccatg ccgccgatgt
     9241 tccagacgtt gttgagcttg aagttgttca gaaacttcat gttgaacccg gcgcggaagc
     9301 ggcgccattc atcgttgaag cggtggccgt tgccttcctt ttctcccatg acgcggcctt
     9361 cgccgttcgg gtcaatccag tccagtccgt actgcatgcg gagggaaacg ttgaattcct
     9421 ggatgtaggg attcttgtgg tcccgttccg agttgaacca cttgaaacgg tcgccgagcc
     9481 atttgcaggc ggaaaagttg tcacgggccg gcagggagtt tccggtagag ggtgcggcag
     9541 cggcaaaggc ggaggctccg agagtcatga ggccgatgac ggggagagta taggtcttca
     9601 tttgttttct atggttggtt tgtctgtgag aaggtcttcc ggggaaggtt cttcctcccg
     9661 gagacggctt ctgtctatca aaccagccac aggagtgtcc aaggcttaag ggtgacaaaa
     9721 tagccacccg tccccctttg gcggttacaa ggtcatgcgg agccatgccc tggcgtccag
     9781 ggcgtctgcg gcggcggcca cttccgcctt tctcttgctg gccccggaac cggctccaat
     9841 ggcgtgacca tgccagaaaa cgcgggattc aaaacggttt tcggcgtctc tcggcccttt
     9901 ttcttccgtt tcataggaag gagtttcggg caggatgtcc tgaaggatag cctggagttc
     9961 ccccttgggg ttgatttcct tgggatggct ggccgcggaa tccagagctt catggaggac
    10021 gcgcagggcc acagccttgg ccgtttcata gttggaatcc agagacatgg ctccgaagac
    10081 ggattcaaat gtgttggcga tgatggaatt tttgctccgt ccgccggccc gttcctcccc
    10141 ctttcccagg gcaatgtgtt tatccagccc caggataaag ccgtatttgc ccagattggc
    10201 gcggctgacg gttcgggcgc gcagctgggt cagttcccct tccggggatt ggggcatgtg
    10261 gtggtaaagg tactgtgtga cggccagctg aagaatggcg tctcccagga attccagccg
    10321 ttcatacgcc cggcgcgttt ccggcttgct gtccgtgctg gggtgggtaa gggcctgaac
    10381 gagcagatcc ggattgttga aacggtaacc cagcttgtct tccagcgcgg tgtgattcat
    10441 cccggaaatg ctagggccgc cgttccggaa atgcaactcc aaacggagag agcttcccgg
    10501 cggggacgga atttgttttc ccgcgtcatc ccggccgctc cacagctttg acatatggga
    10561 ggaggggtat agaatagttt gcgaacgaac gttggagacg atgatgaaga agattgaacc
    10621 aaaagagatt caggataatg ccgtacaatt gatcgggggc gactggatgc tggtgacggc
    10681 gggttctccg gagcatttca acatgatgac ggccagttgg ggcggtttgg ggttcatgtg
    10741 gaagaagccc gtggcgtttg tcgttatccg cccccagcgc cataccttcc gttttattga
    10801 ggccggggac gagctgacgc tttccttttt cagccatgag taccataagg ctctgaccgt
    10861 gtgcggaaca acgagcggac gggatacgga caaggtggcc gcctccggcc tgacgccata
    10921 cgtgacggag aacggcaatg taagttttac ggaagcgcgc ctggtgttgg agtgccgcaa
    10981 gctgtacgcg gagcctctta acccggaagc ctttctggat aaatctattg tgccggagtg
    11041 gtatgccgcc ggggatttcc ataaaatgta tattgtggaa atcctgaacg tatgggtgaa
    11101 ggaatagcgt cccggaaatg ccgcaggcgg acgcctgttc gttgtttctg tccgcgcttt
    11161 ttcagagggg ggcaagggtt ccatcctcca gccggaaggc tggcaggggg cacggagcat
    11221 cgtgcagcca gtccagatgg gtggtggtga tgaggctctg cgcgtccgct ggaagcgact
    11281 gcagaaaggc tatccggcgc gtgggatcca gctccccgaa gacatcgtca atcaggtgga
    11341 tgggtgtatg tcccgtttct tccgtcagga gggaggactg cgccagcttc atggagatgg
    11401 cggtggtgcg ctgctgccct tcggaagcga attgagcggc gtttctgccg ttcagcgtga
    11461 tgtccaggtc atcccggtgg gggccgttct gggtttgtcc gtaccggata tcccggtcca
    11521 tggaggcgca cagccgttca tacaggtctc cttcctccga ggcgcggtaa gcgatggaga
    11581 cctgttcctg ccttccgccg atattgcggt aggccagggc gatatggggc gccaggagcg
    11641 ccagcagatg ggcgcgcagg tttctcagtt ccgtgccgtg cagggccagc tggcgcgtgt
    11701 aggcgtccag ctggagtttg tcccggtgcc tgtgcttgag caggtaattg cgcgttttca
    11761 gcgcccggcg gtagctgaac agggccagtc tgtagcctgg atgccactgg ctgcccagaa
    11821 agtccatgta tttccggcgg gcgtccgcgc cggcctgcac cagggaaagg tcgtcattcc
    11881 ccatccatac cacgggatag ctgtccgcca ggtagctgcg ctggtctttg cggggctctc
    11941 cgttgacgcg gaggtccgga gcgtccggcg cccacaggat gcgccggatt tgccccggaa
    12001 gttctccgcg gatgccgaag gattgttttc cgtgggagac cagaggtccg gtccgggctg
    12061 tgcgcgggga ttgcaggcgc agcaggaagc aaacggcctc cagcaggctg gtttttcccc
    12121 gggcgttgtt tcccaggatg atggccccct gctgcggaat ctgccaggag aagcttccgt
    12181 agcaacggaa gtccattaat ttcagcctgg agatcatggg gccgggaaag gggggttatt
    12241 ccgcagggag ggagcggatg gcgtccatga ttttgtccgt caggtgctgg tatgcatctt
    12301 ttcctttggc gttgagttcc gccggcgtga aggggatggg gtctcccacc gtgaccgtga
    12361 cggggcggag cctgggaaac cgggcgccga tgggaaaggc ttcatacgca ccgctgatgc
    12421 gcaggggctg cacgggaact ttcgttttgc tcaggatgag gccgatcccg cccatgccgt
    12481 catggatttt accatccggc gtgcgggagc cttccggaaa cacgagtacg cgcttgccgg
    12541 atttcagcag gcgtatcacg tgcttgaggc tggcggcatc cgggttttcc tggtcaatgg
    12601 ggatagcctg gcagaggggc agggcccatt tgaaaatgcc ctggaacagc gtcttgcgtg
    12661 cgaaaaaata gatgccgtcc tcataagaaa tgcccagcat gggcggatcc agaaagctct
    12721 ggtgattgct gacgatgagc acggggccgt cttcgatgag tttttcccgg ttgacgactt
    12781 tccaggagaa gaaggctttg gaaatgcttt tgaagagcgt gtagaaaacc cagtagaaag
    12841 agttcatctg gaggagagtt tttgttggat gttgtcggtg atgaaacgga cgacctggtc
    12901 aatcgtcatg tctgacgtat ccaccagaag agcgtcaggc gcctgcgcca gcggggcggt
    12961 ggcgcgggag gaatccttgc ggtcccgctc cgcgatggag tccgtcagtc cctccgcagc
    13021 gcggcgcgcg gccctcactt cctcggaggc ggtgacgaag tacttgaacg gcgtatccgg
    13081 aaaaaccacg gtgcctatgt cccttccttc catcacgacg ggttcccggc ggttatattc
    13141 ccgttgccgt tccaccagca gggcgcgtac ttccgggatg gccgcaatgg tggaaacatg
    13201 gtcgttgacc tgctggctcg tgagttcttc gcccagcaca tgctgtccgc acagaactac
    13261 ggattggctg ccgtccttgc cgaaggagag gggcacggcc ggcagggatt ccagcacggc
    13321 cgccgtgtcc gcagggttga tgccctgttc cagcatgtac caggtaacgg cccggtacat
    13381 ggccccggtg ttgatgaacg tatagccgag gcggtccgcg atgagcttgg cgacggtgga
    13441 ttttccggag gcggcggggc cgtcaatggc gatggctgga tgcat
//
