LOCUS       c00033_gnlPro..        16035 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OGGIOPCJ_73.
ACCESSION   c00033_gnlPro..
VERSION     c00033_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 05:56:43
            Original ID  :: gnl|Prokka|OGGIOPCJ_73
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16035
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16035
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2937:6035]"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2938..6035
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
     cand_cluster    1..16035
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="single"
                     /product="porA"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16035
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="porA"
                     /region_number="1"
                     /rules="(Fer4_7 and TPP_enzyme_C and POR and POR_N and
                     PFOR_II and not (EKR or Fer4_16))"
                     /tool="gutsmash"
     CDS             200..349
                     /locus_tag="ctg33_1"
                     /transl_table=11
                     /translation="MTKDFKNPGLISQVAEFIDKKRIEEGISIDTLCQSAHISKRIYID
                     FKRG"
     CDS             488..2833
                     /locus_tag="ctg33_2"
                     /transl_table=11
                     /translation="MIVFHLFFIKLLIGTVLHLTAPRTLFPEACSTLLYSSDGQLLGAR
                     IAPDGQWRFPPADSLPGKFVTCLLTYEDKRFFRHPGVDPVAIVRAMRINLSRGKVVSGG
                     STITMQLARIARGNRDRTLYEKMVETGYALLLETAFDKHQILNLYASHAPFGGNVVGIE
                     TAAWRYFGRSAADLSWAESATLAVLPNSPALIHPGRNRARLKAKRDKLLTALKEKGILD
                     ETEYGLSLLEPLPEAPVPLPDEAPHLLERLAADAPGTRITTSVNRMLQRQTQEIVNRYA
                     RDYASNHIHNLAALIADAETGEVLAYAGNVTFKADARKGNQVDIITSPRSTGSILKPFL
                     YAAMLHDGQLLPGTLVSDVPLNLNGFSPQNYNKTFYGAVPAHWAIERSLNVPLVRMLSA
                     YNTGRFMSLLKKAGMTTLRFSEEHYGASLILGGAEGTLWDLTGMYASLARTLAHYRTYN
                     GRYDPADIHPLTPYPAPPADPVRSVADKRLTDKPFLSAASIWFAFEAMSALNRPEEEAD
                     WQQFGSMKQVAWKTGTSYGGRDAWAIGTTPRYTVGVWVGNASGEGRPGLTGVGNAAPVL
                     FDLFSLLPGSGWFDMPYDELLPMAICRLSGHKASAICDRVDTLYMPRSADKTEVCPYHR
                     LVHLSADGRFRVNSSCESVGRMIARPWFVLPPSEEYYYRNYHIDYAPLPPVKPGCGEDR
                     GRQIELIYPEHNAILYLPKGFSGKREQFVFKAAHARPDAILYWHLDDTYAGETTDHHQI
                     SFSASPGKHRLTLIDDQGNRKTISFEVK"
     CDS             2938..3171
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_3"
                     /sec_met_domain="Fer4_7 (E-value: 5.2e-14, bitscore: 45.0,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 3.5e-07, bitscore: 22.3,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 3.8e-08, bitscore: 25.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 8.9e-06, bitscore: 18.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKIKGAVVVNTERCKGCNLCVVACPSDVLELHPREVNNKGYHYV
                     YMKNPDDCIGCASCGLVCPDGCLTIYKKRIDN"
     CDS             3269..4351
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_4"
                     /sec_met_domain="PFOR_II (E-value: 4.2e-28, bitscore: 90.1,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 3.1e-49, bitscore: 160.1,
                     seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEEVKLMKGNEAIAHAAIRYGVDGYFGYPITPQSEILETLMAEM
                     PWETTGMVVLQAESEVAAINMVYGGAGTGKRVMTSSSSPGVSLKQEGISYIAGAELPCL
                     IVNVMRGGPGLGTIQPSQADYFQTVKGGGHGDYRLITLAPSSVQEMADFVGLGFELAFK
                     YSNPAIILADGIIGQMMEKVVLPPFHTRRTEEEIIAECPWATQGKTAGRKPNVITSLEL
                     DPAKMEENNIRFQAKYRKIEENEVRYEEFQCEDAEYLLIAFGSSARICQKVVEIARAEG
                     IKLGLLRPITLWPFPTKAIAAYAEKVKGMLSVELNAGQMVEDVRLAVNGKVKVEHFGRL
                     GGIVFTPDEVLNALKKNFEL"
     CDS             4394..4567
                     /locus_tag="ctg33_5"
                     /transl_table=11
                     /translation="MIRGSKIDTILTWLFMVLAVAAVVCYFAFPENRLPFLYCGGAAIC
                     FRLVQYLMRFIN"
     CDS             4691..5455
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_6"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.1e-24, bitscore:
                     77.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEINEIIKPENLVYGKPRLMNENPMHYCPGCSHGVIHKLIAEVIA
                     EMGMEDKTIGISPVGCAVFAYNYLDIDWIEAAHGRAPAIATAVKRLNPGKMVFTYQGDG
                     DLAAIGTAETIHAANRGENIVIVFVNNAIYGMTGGQMAPTTLEGMPTATCPYGRNIALN
                     GYPLKIGDLLAQLEGTCLVTRQSVQTAAAVRKAKKMLRKAFENSMAGKGTSIVEFVSTC
                     SSGWKMTPEKANKWMEENMFPFYPLGDLKNKE"
     CDS             5481..6035
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_7"
                     /sec_met_domain="POR (E-value: 3.7e-36, bitscore: 117.2,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQEIIIAGFGGQGVLSMGKILAYSGLMEGKEVSWMPSYGPEQRG
                     GTANVTVILSDDRISSPVLNEYDIAIILNQPSMEKFENKVKKGGIIIYDGYGIHTPVKR
                     TDVSVYRVDAMDAATEMKNEKAFNMLILGGLLKIVPMVKLENVLLGLKKSLPERHHKLI
                     PMNEAAIKKGMEIITNVQTCH"
     CDS             6141..8252
                     /locus_tag="ctg33_8"
                     /transl_table=11
                     /translation="MKHSLYILLLLIISASALHAQRRPGGDRKGFSLGNLSKANQEVPD
                     SLLIPDSAAISNRRITAYRLTPLLGDPYIAPLDTHKLNFANSTLVESESLAVGYLANTG
                     SPAQTRIFSERKEPRDFLFADAYDYYITDPQNAQYYNTKIPYTNVMYTTMGGSESKNER
                     LKGTLTMNFGPKINVGGDLDYIYSRGYYKNNGNKLLSYRLFGSYKSDRYEAHAYLSNFN
                     FINYENGGLANDSVITNPDQYFAGERNQDDPKAFNTRYPVKAWNRVRGKQYFLSHHYNL
                     GFERELEGEVDTLGNPVKVFIPVSSIIHTLEYQDNRRRFRSEAGENLNECYLTPDGYPR
                     VFGLENGTGVDDRTSYWNLRNTFGLSLREGFQDWAKFGITAFATFDKRKFQLPAQIPGL
                     SYDPEYGSGLNASPSTIEFPITQVYDEFSTYIGAEISKRRGNILTYNARGELCVVGDDI
                     GEFRATGNLQTKFKLLKKDATISAEGYIKNVTPSFYMRHFHSRYFWWDNRDMNMIQQIY
                     AGVKINLESTRTQLSAGVESIQNYVFFNKQGMPEQKSGNLQVINARIKQDVMYRAFGWE
                     NEVAYQLSSDKSVLPLPQISLYTNMYLKFKVAKVLMVQLGANMYYNTSYYAPYYEPATQ
                     QFQVQDEVKVGNFPLVNAYVNFHLKQARFFVMGYNLGSKFVNPNYFSLAHYPLDPFVLK
                     MGVAVTFNN"
     CDS             8257..9084
                     /locus_tag="ctg33_9"
                     /transl_table=11
                     /translation="MKSRKLIGVYTGLLIIAVATMIMLWRLKTMPKAEVFPRDYPEIKE
                     EGILRLVTEYNQSGYYVAGDTIEGFQYELSQAIAQLSGLEIQIFLEMSLAESFDMLEEN
                     NCDAVARNIPITSEIKEKYLFTEPIVLDKQVLIQRTEAANNGLKPIRNQLDLAGKTLYI
                     PKDSPAQLRLQNLGHEIGDTIYVIEDELYSGEQLAIMVAKGDIDYAVCDQQTAVLSQKQ
                     LPEIDIKTDISFTQLQSWAVRKDSPILLDSLNSWLEQIRKNGTFDKIYKKYYK"
     CDS             complement(9094..10779)
                     /locus_tag="ctg33_10"
                     /transl_table=11
                     /translation="LLYRTQLFFQKSYFFKGRLIFVIFSGEDCDKNKYLYTQISVLKHF
                     VYMGGIYGGKDIRPISQKQDSLHGLINTILDKLPLGVFVKDAEDGFRYLYWNRFMEEIT
                     GIGTEEVEGHNDFELSFDAIMPAEERLGLDRDVMETGRTIEFSGKISDAYGIPKDIEVT
                     KFPIALSNGKPLLLALWRDVTVRNKMENTLRRSQVLTKMALHSNDIRLCSIFVNPDSKR
                     NYDDSVVQVNNWLPGKEDELVDISWPRFAARVHPDDRERHDEAFRKLCSGEISEMKIEL
                     RVKYPGMDHYHWRESSATVYERDERGRVLVILGCTINIQERKGQELNLEEAKHKAELAD
                     KMKSKYLADMSHEIRTPLNAITGFSELMAFADSDEERREYYEIIKTNNLLLMQLINDIL
                     DLSKIEADAIRISYEPVDINGLMDTIFASIKLRMPEGVQLFLEKGSCTCCFGADSIRLL
                     QLINNLANNAIKNTKQGSITLGYTCLPDKCLKFYVKDTGTGIAKDKLESLFTRFVKVND
                     YVEGIGLGLAICQGLVTKMGGSMHVESELGVGSTFSFVLPSHEG"
     CDS             10827..12110
                     /locus_tag="ctg33_11"
                     /transl_table=11
                     /translation="MRFDELDLEEAVLDGLDAMNFLETTPVQELTIPVILEGKDIIACA
                     QTGTGKTAAYVLPVINELSKGLHPANAINAIIMAPTRELAQQIDQQIEGFTYFVPVSAV
                     AVYGGTDGIAWEQQKRGMEMGADIVIATPGRLLSHIKLGTVDLSQVSFFVLDEADRMLD
                     MGFYDDIMQVYKLLPATCQTIMFSATMPPKIRTLAQTILKNPEEVKIAISRPPETIMQT
                     AYVCYDMQKLRILEDLFSKSRPQRVIIFSSSKMKVKELASTLKRMKFNVAAMHSDLEQS
                     QREEVMKEFKNGRIDILVATDVVSRGIDINDIKLVINFDIPHDPEDYVHRIGRTARGTN
                     GEGLAITFISTEEQFQFKRIEEFLDKEIYKIPVDPKFGETPLYEPEKYSNMRRGRGRPR
                     KDGGKGKSDNRSGSGNNQRRRGRPRKEA"
     CDS             complement(12277..14325)
                     /locus_tag="ctg33_12"
                     /transl_table=11
                     /translation="MQKYNILELNEKLLPELQSIAEELGIKKVSSLKKEELVYRILDEQ
                     AISYAGIQAEKEKEKEAKKAERQTKAKKTKAAAPKGAKADAKTKVAAPATPVEVSVEEV
                     APEAPEQPERKRRTRIDKKEKVAAAVVPVQKNEEAAVSKSPVSANAPVSETLVQVADAT
                     ADVPAETVKPAAKKVVKKTDKPVEKPLLPPVVVESDNGELPAEIAPEVTEEPAVVETPA
                     ASTPSDEPKRVVFRHPDTKSVLDQLFPFSSTPAKPEPKAREEQPAAAQQQNNPRQNNNR
                     QNNQNNHNNQRNNNNNNAVQEKQYEFDGILTGVGVLEMMPDGYGFLRSSDYNYLTSPDD
                     IYVSQSQIKLFGLKTGDVVEGAIRPPKEGEKYFPLVKVDKINGRTPEEVRDRVPFDHLT
                     PLFPDEKFMLTARKSSKVYDNIAVRVVDLFSPIGKGQRGLIVAQPKTGKTMLLKDIANA
                     IAANHPEVYMIILLIDERPEEVTDMARSVDAEVIASTFDEPAERHVKIAEIVLNKAKRM
                     VECGHDVVILLDSITRLARAYNTVQPASGKVLSGGVDANALQKPKRFFGAARNIENGGS
                     LTILATALTETGSKMDDVIFEEFKGTGNMELQLDRKLANKRVYPAVDITASSTRRDDLL
                     QDENTVNRMWILRKYLADMNSMEAMEFVKKRMEQTFDNMEFLASMNG"
     CDS             complement(14509..15843)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP_bind_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_13"
                     /sec_met_domain="ATP_bind_3 (E-value: 3.1e-49, bitscore:
                     159.5, seeds: 28, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDVVRAYIEKYRLLTENRPVLVGVSGGADSIALLTILVESGYSC
                     IAAHCNFHLRGDESLRDEQFVREYARKLDVPFLMTDFDTRKYAADRHLSIEMAAREVRY
                     GWFEEQRAATGAQAVAVAHHRDDSVETLLMNLVRGTGIRGMSGIRPRNGFVVRPLLAVS
                     REDILEWLAGRGLTYVTDSTNLSDAYTRNFIRLRVLPLLEEINPSVKDAIARTSEHLSA
                     AEAVYLHVVEEARNAVVEQGDRLSIAALMRYPSPDAILYELLKTYGFTRPVAEDVYLSL
                     TKESGKTFFSSTHRLIKDRDYLLLSPLVKEEVREYTLTGGEKVWSGPVELSFEKIVIKE
                     DFHIRKDKNIAYFDYDKLAFPLTLRTWKEGDWFIPFGMKGRKKLSDYFSDHKFSRLDKE
                     RTWLLCSGGAVIWIVGERSDNRFCLDKTTKSVLVVNFFPTKSESN"
ORIGIN
        1 ctgtatttca ataatttcaa agaccgatta gccaactttt attggacagt agtgataata
       61 ctattaaaat taattataca tttgcactcg ctgtcataag cagcataaaa atacggacta
      121 tccggcaaac aaaagttccc acataaggga accggacaac cggaaacttc ctgctattta
      181 actaattata actcatatca tgacaaaaga cttcaaaaat cccggcctaa tcagccaagt
      241 tgccgaattc atcgacaaga aaaggatcga agagggcatc agcatcgaca ccctctgcca
      301 atcggcccac atcagcaaac gtatctacat agactttaaa aggggctgaa gccggcaacg
      361 acgctccact ggttcttccg cctcgcaaat accttcagcc agcacactga cgaagaaaaa
      421 ttcaaggaaa tatggttgga aatcgcgaaa ataatgacta acttagagga gtaaaaccaa
      481 atggcgaatg attgtcttcc acctgttttt cataaagctg ctgataggaa cggtcctgca
      541 tctgaccgcc ccccggacac tctttccgga ggcctgctcc accctgctct attcttccga
      601 cgggcagttg ttaggggcac ggatcgcacc ggacgggcaa tggcgtttcc ctccggcaga
      661 cagtcttccc ggcaagttcg tgacctgcct gctgacctac gaagacaaac gtttcttccg
      721 gcatccggga gtagacccgg ttgccatcgt ccgagccatg cggatcaacc tcagccgggg
      781 caaggtcgtc agcgggggga gcacgatcac catgcagctg gcacggatcg cgcggggcaa
      841 ccgcgaccgt accctgtatg aaaaaatggt cgaaaccggc tatgcccttc tcctggaaac
      901 agccttcgac aaacatcaga tcctgaacct ctatgcctcg cacgccccgt tcggagggaa
      961 tgtggtaggc atcgagacgg cggcctggcg ctatttcggg cgaagcgccg ccgacctctc
     1021 gtgggccgaa agcgccacac tcgccgtcct gcccaactcg cccgccctga tccatcccgg
     1081 acgtaaccgg gcacggctga aagccaaacg cgacaagctc ctgaccgcct taaaggaaaa
     1141 agggatactg gacgaaaccg aatacgggct gtcgctcctc gaaccgcttc ccgaagcgcc
     1201 cgtgcctctg cccgacgaag cccctcacct gctcgaacgg ttggcggccg acgctccggg
     1261 aacgcgtatc acgacctccg tcaaccggat gttgcaacgc cagacacagg agatcgtcaa
     1321 ccgctacgcc cgcgactacg cctccaacca catccataac ctggccgccc tcatcgccga
     1381 tgccgaaacg ggcgaggtgc tggcctatgc gggaaacgtc actttcaagg ccgacgcccg
     1441 caaagggaac caggtagaca tcatcacttc gccacgcagc acgggcagca tcctgaagcc
     1501 ctttctttat gccgccatgc tgcacgacgg gcagctgctc cccggtacgc tcgtttcaga
     1561 cgtccccctg aacctgaacg gcttctcgcc gcaaaactac aacaagacgt tctacggggc
     1621 ggtcccggca cactgggcga tcgaacgttc gctcaacgtc ccgctggtac ggatgctttc
     1681 ggcctacaac acggggcggt tcatgtcgct gctgaaaaag gcggggatga ccacgctgcg
     1741 cttttccgaa gaacattacg gggcttcgct gatcctggga ggcgccgaag ggacgttatg
     1801 ggacctcacc ggcatgtatg cttcactggc gcgtacgctc gcacattacc ggacttacaa
     1861 cgggcggtat gacccggcgg atattcatcc gctcactcct tacccggctc ctccggccga
     1921 cccggtccgc tcggtcgccg acaaaaggct tacggacaag ccgttcctct ccgccgcctc
     1981 catctggttc gccttcgaag cgatgtcggc actgaaccgc cctgaagaag aggcggactg
     2041 gcagcagttc ggctccatga agcaggtggc ctggaaaacg gggacgagct atggcggacg
     2101 ggacgcctgg gcgatcggga caaccccgcg ctatacggtc ggcgtatggg tgggcaacgc
     2161 ttcgggagaa ggccggccgg gactgacagg cgtgggcaat gccgctcccg tcctcttcga
     2221 cctgttctcg ctccttccgg gaagcggctg gttcgacatg ccttacgacg aactcctccc
     2281 gatggccatc tgccgtctca gcgggcacaa ggcatccgct atctgtgacc gggtagacac
     2341 gctctacatg ccgcgctcgg ccgacaagac ggaagtctgc ccctaccacc ggcttgtcca
     2401 tctttctgcg gacggccgtt tccgggtgaa cagctcgtgc gaatcggtcg gccggatgat
     2461 cgcacgcccg tggttcgtac tgcctccttc cgaagaatat tattaccgga actatcatat
     2521 cgactacgct cccctgcctc ctgtcaaacc gggatgcggc gaagacaggg gccggcagat
     2581 cgaactgatc tatccggagc ataacgccat cctttatctt ccgaaaggct tctccggcaa
     2641 acgggagcag tttgtcttca aagctgccca cgcccgtccg gatgccatcc tctactggca
     2701 tctcgacgac acgtatgccg gcgaaacgac agaccaccac cagatcagct tctccgcttc
     2761 ccccggcaaa catcgcctga cgctgatcga cgaccagggc aatcgaaaga caatatcgtt
     2821 cgaggtgaaa taatcaaaac agtttctaaa aaaggctctt tctgtaaagt ttttactacc
     2881 tttggcagtc gcaagtgaga tagttagtgt tacattagtt tttaaatata ataaattatg
     2941 gcgaagataa aaggagctgt tgttgtaaac acagagcgat gcaaaggatg taacctctgc
     3001 gtagtagcct gcccgtcgga tgttctcgaa ttgcacccgc gtgaagtaaa caacaaggga
     3061 taccattatg tgtacatgaa aaaccccgat gactgcatcg gttgtgcaag ctgcgggttg
     3121 gtttgtccgg acggttgttt gaccatctac aagaagagaa ttgacaattg acaatgcaca
     3181 attgacaatt taacaaacag aaaaaggaat cagaatatta atcacaaaac aaaattgtca
     3241 attgtcaatt gacaattaaa tataaggtat ggcagaagaa gtaaaattaa tgaagggtaa
     3301 cgaagccatc gcccatgcgg ctatccgcta cggtgtggac ggttacttcg gctacccgat
     3361 cactccgcag tcggagatac tcgaaaccct gatggccgaa atgccgtggg aaacaaccgg
     3421 aatggtcgtg ttacaggctg aaagtgaagt ggcagccatc aatatggtat atggaggtgc
     3481 aggtacgggc aaacgtgtga tgacctcctc gtccagcccc ggtgtcagtc tgaaacaaga
     3541 aggtatatct tatatcgcag gagccgaact gccctgtctg atcgtaaacg tgatgcgtgg
     3601 cggtcccggc ctggggacaa tccagcccag ccaggcagac tatttccaga ccgtcaaagg
     3661 cggcggacat ggcgactacc gcctgatcac gctcgctccc tcttccgtac aggaaatggc
     3721 ggactttgtc ggactgggtt tcgaactcgc tttcaaatac agtaatccgg ccattattct
     3781 ggcagacggc atcatcgggc agatgatgga aaaagtggta ttgcctcctt tccatacacg
     3841 ccgtacagag gaagaaatca tagccgaatg cccgtgggcc acacagggaa agacagccgg
     3901 ccgtaaaccg aatgtcatta cttcactgga gctggacccg gcaaagatgg aggagaacaa
     3961 catccgcttc caagctaaat atcggaagat cgaagaaaat gaagtccgct acgaagagtt
     4021 ccagtgcgaa gatgccgaat atctgctgat cgctttcggt tcttctgccc gtatctgcca
     4081 gaaggtggtg gaaatagcac gtgcggaagg catcaagctc ggcttgctcc gtcccatcac
     4141 tttgtggccg ttcccgacaa aagcgatcgc cgcttatgcc gagaaagtaa agggcatgct
     4201 ttccgtcgaa ctgaacgccg gacagatggt cgaagacgta cgtctggccg taaacggcaa
     4261 agtaaaggtt gaacatttcg gccgtctcgg aggtatcgtg ttcacgccgg atgaagtgct
     4321 gaatgcgctg aaaaagaatt ttgaattatg attgatttgt aatacataat tcataaatca
     4381 taaattaaca acgatgattc gcggaagtaa aattgatacg atattgacct ggttattcat
     4441 ggttttggca gtggcagcag tcgtttgcta cttcgccttc cctgaaaacc ggctgccatt
     4501 cctgtattgc ggtggcgcgg cgatctgttt ccgcttggtt caatatctga tgagatttat
     4561 aaattaataa tgtggcaatg tgccaatcag acaatgtgcc aatccatatt gttgttgacg
     4621 cattccttaa ctggcacata ggcaaattac cacattatta atataagcac attgaaaaat
     4681 tattcatagt atggaaatta acgaaataat aaaaccggaa aacctggtat atggaaaacc
     4741 caggttgatg aatgaaaatc ccatgcacta ctgtcccggt tgcagccacg gcgtgataca
     4801 caagctgata gccgaagtga tcgccgaaat ggggatggaa gataaaacga tcggcatctc
     4861 tcccgtcgga tgcgccgttt ttgcctataa ctatctggat atcgactgga tcgaagcggc
     4921 ccacggacgt gcgcctgcca tcgcgacagc cgtcaagcga ctgaatccgg gcaagatggt
     4981 gttcacgtac cagggcgacg gcgacttggc tgccatcggt accgccgaaa caatccatgc
     5041 tgccaaccgt ggagaaaata tcgtgatcgt atttgtcaac aatgccatct atggtatgac
     5101 aggcggtcag atggctccta ccacactgga aggaatgccg actgcaacct gtccgtatgg
     5161 ccgtaatatc gccctaaacg gttatccttt gaagatcggc gacctgcttg cacaactgga
     5221 agggacctgc ctggtcaccc gccagagcgt acagaccgcg gcagccgtcc gcaaggctaa
     5281 aaagatgctt cgcaaggcat tcgaaaactc gatggccggc aaaggcactt cgattgtcga
     5341 attcgtttcc acctgctcgt ccggttggaa aatgacacct gagaaagcta acaaatggat
     5401 ggaagagaat atgttcccgt tctatccgtt aggagatctc aagaataagg aataataagt
     5461 aattattaat ttttgaagca atgaagcaag aaattataat agcaggtttc ggtggacaag
     5521 gggttttgtc aatgggtaag atcctggctt attccggcct gatggaagga aaggaagtca
     5581 gttggatgcc ttcttacggc ccagaacaac gaggcggtac agccaacgta accgtcatcc
     5641 tgagcgacga ccgcattagc tctcccgtat tgaacgaata tgacattgcc atcatcctga
     5701 accaaccttc gatggagaag ttcgaaaaca aggtgaaaaa aggcggtatc attatttatg
     5761 acggatacgg aatccataca ccggtgaaac ggaccgatgt cagtgtatat cgtgtggatg
     5821 cgatggacgc ggctaccgag atgaaaaacg agaaagcatt caatatgctg atcctcggcg
     5881 gactgctgaa aatcgttccg atggtgaaac tggaaaacgt tttgttaggc ttgaagaaat
     5941 ccctgcccga acgccaccac aagctcatcc cgatgaacga ggcggctatc aagaaaggca
     6001 tggagattat aaccaatgtg caaacgtgcc attaaggcgc ttagctaaat gtgccaatat
     6061 gccaataaaa atataactaa tattaattgg catattggca cattgttcat attggtacat
     6121 tatcactatc tttgcccctc atgaagcata gcctatacat attattactc ttgataatat
     6181 ccgcttcggc cctgcatgca caacgccgac caggtggaga ccggaaagga ttctcactcg
     6241 gaaacctatc caaagccaat caggaagtcc ctgacagcct gctgattcca gacagcgcag
     6301 caataagcaa cagacgtatc acggcctatc ggctaacccc tctgttgggc gatccttata
     6361 ttgccccgtt ggacacgcat aaattgaatt tcgccaacag cacgctggta gaatccgaat
     6421 cgctggcagt cggctacctg gccaatacag ggtcaccggc acaaacccgc atcttttccg
     6481 aacgtaagga accacgggat ttcctgtttg ccgacgctta cgattattat atcacggacc
     6541 ctcagaacgc acagtactac aacacgaaaa tcccttatac aaacgtgatg tacacgacta
     6601 tggggggaag tgaaagcaaa aacgaacggc tgaaaggcac gctgaccatg aacttcggtc
     6661 cgaagatcaa cgtaggtggc gacctggact atatctacag ccgcggatat tacaagaata
     6721 acggtaataa gctgttaagc taccgccttt tcggcagtta caagtcggat cgctacgaag
     6781 cgcacgctta cttgagcaac ttcaacttca tcaattacga aaacggaggc ttggccaacg
     6841 actcggtcat cactaacccg gaccaatatt ttgccggcga gagaaaccag gacgacccca
     6901 aggcattcaa tacacgctat ccggtcaagg catggaaccg ggtacgtggc aaacagtatt
     6961 tcctcagcca ccattataac ctcggattcg agcgcgaact ggaaggggaa gtggatacgc
     7021 tgggaaatcc cgtgaaagta tttattcccg tatccagtat cattcataca ctggaatatc
     7081 aggacaaccg ccgccgtttc cgatcggaag cgggcgagaa cctgaatgaa tgttatctga
     7141 ccccggatgg atacccgcgt gtattcggtt tggaaaacgg cacgggtgtc gacgaccgca
     7201 cttcctactg gaatctgcgc aatacgttcg gtctttccct ccgcgaaggt tttcaagact
     7261 gggccaagtt cggcatcact gcctttgcca ctttcgacaa gcgcaaattc cagttgccgg
     7321 cccagatacc gggattgtct tacgaccccg aatatggaag cgggttaaac gcctctcctt
     7381 ccaccatcga atttccgatt acacaagtgt atgatgaatt ctcgacatat atcggagccg
     7441 aaatctccaa acgccgggga aacattctga cttacaatgc ccgtggagaa ctttgtgtcg
     7501 taggcgacga tatcggggaa tttcgggcca cgggaaacct gcaaaccaaa ttcaagctat
     7561 taaaaaaaga tgcgacgatc agtgcggaag gatacatcaa gaatgtcact ccttccttct
     7621 atatgcgtca cttccattcc cgctatttct ggtgggataa ccgggatatg aacatgatcc
     7681 agcaaatcta tgccggagtc aagatcaacc tggagtccac acggacacag ttgtctgccg
     7741 gggtcgaaag catacagaac tatgtattct tcaacaaaca aggaatgccg gaacagaaaa
     7801 gcgggaatct gcaagtgata aacgcccgca tcaaacaaga tgtcatgtac cgcgctttcg
     7861 gatgggaaaa cgaagtggcc taccagctga gcagcgacaa aagcgtactg cctttgcctc
     7921 aaatcagcct gtataccaat atgtatctga aattcaaggt agcaaaggtg ctgatggtgc
     7981 aattgggagc caatatgtat tataacactt cttactacgc cccgtattac gaaccggcca
     8041 cacagcagtt ccaggtacag gacgaagtga aagtcggcaa tttcccgctt gtcaatgcct
     8101 acgtcaactt ccacctgaaa caggctcgtt tctttgtgat gggttataac ctgggttcca
     8161 agttcgtcaa tccgaactat ttctcgctgg cgcactatcc gctggatccg ttcgtcctga
     8221 aaatgggcgt ggctgtcaca ttcaacaact gatcttatga aatcgaggaa actgatagga
     8281 gtctacaccg ggctgctgat aatcgccgta gcaaccatga tcatgttatg gcgcctgaaa
     8341 accatgccga aggctgaagt cttcccacgc gattatccgg agatcaaaga agaaggaatc
     8401 ctgcggctgg tgaccgaata caatcaatcg gggtattatg tggcaggtga cacgatagaa
     8461 ggtttccaat atgaactgag ccaggctatc gcccaattat caggtctgga aatacagata
     8521 tttttggaga tgagcctggc cgaaagcttc gatatgcttg aagagaacaa ttgcgatgcc
     8581 gttgcccgca atatcccgat caccagcgag atcaaagaga aatatctgtt caccgaaccg
     8641 atcgtcctcg acaaacaagt cctgatacaa cggacggaag cggccaataa cgggctcaag
     8701 cccatccgca accaactcga tctggccggt aagaccctat atatccccaa agattctccc
     8761 gcccagctca ggctacaaaa cttaggacat gagatcggcg atacgatcta cgtgatagaa
     8821 gacgaattat actccgggga acagcttgcc atcatggttg ccaaaggaga tatcgattat
     8881 gccgtttgcg accagcagac ggctgtcctt tcccaaaagc aactcccgga aatagatatc
     8941 aaaacagaca taagtttcac gcaactccaa tcctgggcag tccgcaaaga ttcccctatc
     9001 ctgctcgaca gcctgaacag ctggctggaa cagatacgca agaacggtac attcgacaag
     9061 atatacaaga aatattataa ataatgcatc actttatccc tcatgcgacg gcagcacgaa
     9121 ggagaaagtc gaaccgaccc ctaattcgga ttccacgtgc atggaaccac ccattttcgt
     9181 aaccagccct tggcagatgg caagccccaa accgatacct tccacataat cgttcacctt
     9241 aacgaagcgt gtgaaaaggc tctccagttt atcttttgca atgccggttc ccgtatcctt
     9301 cacataaaat ttcagacatt tatccggcag gcaggtatat cccagcgtga tacttccctg
     9361 cttggtattc ttaatcgcat tattcgccag attattgatc aattgcaaca gacggatact
     9421 atcggctccg aaacagcacg tgcagctacc tttttccaag aacaactgca ctccttcggg
     9481 catacgaagt ttgatagagg cgaatatcgt atccatcagc ccgtttatat cgaccggttc
     9541 ataactgatc ctgatagcgt cggcttcgat cttggacagg tcgagtatat cgtttatcag
     9601 ttgcatcagc agcaggttat tggtcttgat gatctcataa tattccctac gctcctcatc
     9661 cgaatcggca aaagccatca attcggaaaa accggtgatc gcattcagcg gggtgcggat
     9721 ctcatggctc atatccgcca gatacttgga cttcatctta tcggcaagct ccgccttgtg
     9781 cttggcttct tccaggttca gctcctgccc tttgcgttcc tgtatgttga tcgtacatcc
     9841 caggatcaca agcacccttc cccgttcatc ccgttcgtag acggttgccg acgattcacg
     9901 ccagtggtaa tgatccattc ccgggtattt cacacgcaac tcgattttca tttccgatat
     9961 ctctcccgaa cataatttcc gaaaagcctc atcgtgtctc tccctgtcgt caggatgaac
    10021 ccgcgcggca aaacgaggcc atgaaatatc gaccagctcg tcttctttac ccggcaacca
    10081 gttatttacc tggacaaccg aatcatcata attccgtttg ctgtcaggat tcacgaatat
    10141 ggaacagagg cggatatcat tggaatgcag ggccatctta gtaagtacct gcgaacgtct
    10201 caaggtattc tccatcttgt tgcggaccgt gacgtcacgc cacaaagcca gcaaaagggg
    10261 tttgccatta ctcaaggcaa tcgggaattt cgtgacttcg atatccttcg ggatgccata
    10321 cgcatcagaa atcttcccgc taaattcaat agtcctaccc gtctccatga catcacgatc
    10381 cagccctaaa cgctcttctg cgggcatgat cgcatcaaaa ctcagttcga aatcattgtg
    10441 accctcaact tcttccgtac cgataccggt tatttcttcc atgaaacggt tccaatacag
    10501 atacctgaaa ccatcttctg catcttttac aaaaacgcct aacggtagtt tatccaaaat
    10561 cgtattgatc aatccatgta atgaatcttg cttttgtgag attggccgga tgtccttccc
    10621 accataaatg ccgcccatat aaacaaaatg ctttaaaacg ctaatttggg tataaagata
    10681 tttattttta tcacaatctt ccccggaaaa tatcacaaaa atcaatcttc ccttgaaaaa
    10741 ataactcttt tgaaagaaga gctgcgttct atataacaaa tattgccaaa tattatctac
    10801 ctttaccggg aatttaatga tgaaagatga gatttgacga attggactta gaagaggccg
    10861 tattggacgg ccttgacgca atgaattttc tggagacaac tccagtacag gaactgacga
    10921 ttccggtcat tttagaaggg aaagacatta ttgcctgtgc acagacaggg acaggaaaga
    10981 ctgcggctta tgtgttgccg gtgatcaatg aactcagcaa aggattacat ccggccaatg
    11041 ccatcaatgc catcatcatg gctcccacac gcgaattggc ccaacagatc gaccagcaga
    11101 tcgaaggttt cacctatttt gtcccggttt ccgccgttgc cgtctacgga ggcacggacg
    11161 gtattgcctg ggaacagcaa aagcgaggga tggaaatggg ggccgatatc gtgatcgcta
    11221 cccccggacg tctgttgtcg catatcaaac tgggcactgt cgatctgtcg caagtatcct
    11281 tcttcgtcct ggatgaagcg gaccggatgc tcgatatggg attttatgac gatatcatgc
    11341 aggtctacaa actactgccg gcaacctgcc agaccatcat gttctctgcc acaatgcctc
    11401 ccaagatccg gacactggcc caaacgatcc tgaaaaaccc ggaagaagtc aagatagcca
    11461 tctcccgtcc acccgaaaca atcatgcaaa cggcctatgt ctgctatgac atgcagaaac
    11521 tacgcatatt ggaagacttg ttctcaaaga gccgtccgca gcgtgtcatc attttttcgt
    11581 cctcgaaaat gaaagtaaaa gagctggcat ccactctcaa acggatgaag ttcaacgtcg
    11641 cagccatgca ttctgacctt gagcagtcac agcgtgaaga ggtgatgaaa gagttcaaga
    11701 acggacgtat agacatcctc gtcgccactg acgtcgtctc gcgcggtatc gatatcaacg
    11761 acatcaagct ggttatcaat ttcgacattc cccacgaccc ggaagactac gtgcaccgca
    11821 tcggccgtac cgcccgcgga acaaacggcg aagggctggc catcactttc atttcaaccg
    11881 aagaacaatt ccaattcaaa cgcatcgaag aattcctgga taaggaaatc tataaaatac
    11941 cggtcgatcc caaattcggc gaaacacctt tatacgagcc cgaaaaatac tccaacatgc
    12001 gtcgtggcag aggacgcccc cgcaaagacg gcggaaaagg gaaaagcgac aaccgctccg
    12061 gcagcggcaa caaccaacgc cgcagaggaa gaccgaggaa ggaagcatag gctaacgttt
    12121 ataaatatgt cgaccggcat ttatacaaat gccggtcgac gattataagt gcatagcgtt
    12181 gcaaaatata gaaaacagag attcgaatcc aatataaaaa acgcagacca ggccgagccc
    12241 gatctgcgtt tttatcaata tcgagaatcc cctaacttat ccgttcatcg aagccaagaa
    12301 ctccatatta tcgaatgtct gttccatgcg cttcttgaca aattccatag cctccataga
    12361 gttcatatcg gccaggtact tacgcaggat ccacatacgg ttcacggtgt tttcatcctg
    12421 caacaggtcg tcgcggcgcg tgctggacgc tgtgatatcg acagccggat aaacacgttt
    12481 gtttgccagc ttgcgatcca actgcaactc catattaccc gtacctttga attcttcaaa
    12541 gatcacatcg tccatcttcg aaccggtttc agtcaatgcc gttgccagga tcgtcaggct
    12601 gccgccgttt tcgatgttac gggcagcccc gaagaaacgt ttcggtttct gcaatgcgtt
    12661 cgcatccaca ccaccggaga gcactttacc ggaagccggc tgaaccgtat tgtaagcacg
    12721 agccagacgt gtgatagagt ctaacaggat cacgacatca tgtccacatt ccaccatacg
    12781 tttagcctta ttcaatacga tttcggcaat tttcacatgg cgttcagccg gttcgtcgaa
    12841 agtagaagca atcacttcgg catctacgct acgggccata tcggtcacct cttcaggacg
    12901 ttcgtcgatc agcaggataa tcatatacac ttcaggatgg ttggctgcga tcgcattggc
    12961 gatatccttc aacagcatcg tcttaccggt cttcggctgt gccacgatca gaccacgctg
    13021 tcccttgccg atcggcgaga acagatctac tacacgtacg gcgatattat catatacttt
    13081 cgaagacttg cgggccgtca acatgaattt ttcgtccggg aaaagcggag tcagatgatc
    13141 gaaaggaaca cggtcacgga cttcttcagg cgtacggccg ttgatcttgt ccactttgac
    13201 aagcgggaaa tatttttcac cttccttcgg aggacggata gccccctcca ccacgtcgcc
    13261 ggtcttcagg ccgaacagct tgatctgcga ctgcgatacg taaatatcat ccggggaagt
    13321 caggtagtta taatcggaag aacgcaagaa accatatccg tcaggcatca tttccagcac
    13381 accgacacct gtcagtatac cgtcaaactc atactgtttt tcctgcacag cattgttatt
    13441 attgttgttg cgctggttgt tatgattatt ctggttgttc tgtctgttgt tattctggcg
    13501 aggattgttc tgctgctggg cggctgcagg ttgttcttca cgcgctttcg gttccggttt
    13561 tgcaggtgtg gaagagaatg ggaaaagttg atcgagaact gatttggtgt ccggatggcg
    13621 gaataccaca cgtttaggtt cgtctgacgg agtcgaagcg gcaggagttt ccacgacagc
    13681 cggttcttcc gttacttcag gagcgatttc ggccggaagc tctccgttat ccgattccac
    13741 gacaacagga ggaagcaacg gtttctctac aggcttgtca gtcttcttaa ccactttctt
    13801 tgctgccggt tttaccgttt cggcagggac gtcggccgta gcatcagcta cctggacaag
    13861 agtttcggat acaggagcat tggctgaaac cggacttttg gaaacggctg cctcttcgtt
    13921 tttctggaca ggaacaacag ccgcggccac tttttctttc ttgtcaatac gagtccgtct
    13981 tttacgttcg ggctgttccg gagcttccgg agcgacctct tctaccgaaa cttcaacggg
    14041 tgtggcggga gcagcgactt tcgttttggc atcagctttt gcgcctttcg gagccgcagc
    14101 ttttgttttc ttagccttag tctgcctttc tgctttcttt gcttcctttt ctttctcctt
    14161 ttcagcctgg atgccggcgt atgaaatggc ctgttcgtca agaattctgt atacaagttc
    14221 ctctttctta agggaactta cttttttaat acctaactct tccgctatac tttgcaactc
    14281 aggaaggagt ttttcattta gttctagaat gttatatttt tgcataatgc gaagtgaata
    14341 ataaaaacga cgtacttaca cgaccggaca cggcacgcgt acaacgcaat cattgtatct
    14401 tttataattt gataattaat aatttcatgt gaaaaccgga ttgttgagct aatttgaatc
    14461 attagtaaca catctgcgga gtaaatcttt gcaaatgtaa taatattttc agttactctc
    14521 gctttttgtc ggaaaaaaat tcacaactaa cacactttta gttgttttgt ccaggcaaaa
    14581 acgattatcg gaacgttctc ctacaatcca gataacagcg cctccgctgc ataaaagcca
    14641 cgtccgttcc ttatctaaac ggctgaattt atgatccgag aaataatcgc ttaatttctt
    14701 ccgccctttc atgccaaaag gaataaacca atctccttct ttccatgtac gcagggtaag
    14761 cggaaaagcc agtttgtcgt aatcgaaata agcgatattt ttatctttcc ggatatggaa
    14821 atcttcctta ataacaatct tctcgaaaga aagttcgaca ggaccggacc aaactttctc
    14881 gccaccggtc agtgtatatt cacggacctc ttcttttaca aggggagata acaataaata
    14941 gtcccgatct tttatcaacc ggtgcgtaga agagaaaaag gttttgcccg attctttcgt
    15001 cagggacaaa taaacatcct ccgccaccgg acgagtaaag ccataggttt tgagtaactc
    15061 gtataaaata gcatcgggcg acgggtaacg catcaaggcg gcaatcgaaa ggcggtcccc
    15121 ttgctcgacc acggcattcc tcgcctcttc caccacatgc agataaacgg cttcggctgc
    15181 cgacagatgt tcggacgtac gggcgatcgc atccttcacg gaaggattga tttcctccag
    15241 aagcggaagg acacgcaggc ggataaaatt gcgcgtataa gcatcggaaa ggttggtact
    15301 gtcggtcaca tacgtcaaac cgcgtccggc aagccactcc aagatatcct cacggctcac
    15361 ggcaagcaaa gggcgcacca cgaaaccgtt cctcggacga atcccgctca ttcccctgat
    15421 gccggtccca cgtaccagat tcatcaaaag cgtttccaca ctgtcgtcac gatgatgagc
    15481 cacagcgaca gcctgcgccc cggttgcagc ccgttgctct tcgaaccagc catagcgcac
    15541 ctcgcgggca gccatttcaa tggagagatg ccggtcggct gcatattttc gggtatcgaa
    15601 gtccgtcatc aggaaaggga catccagttt tcgggcatac tcccttacaa actgttcatc
    15661 acgcagggat tcgtctcccc gcaaatgaaa attacaatgc gccgcaatac aggaatagcc
    15721 cgactccacc aaaatggtga gtagggctat tgaatctgct ccgccactta caccgaccag
    15781 aaccggacgg ttttccgtaa gcaaccgata tttctctata tatgcacgga caacgtcgcg
    15841 catccgatta ttcttctatg cctgccaatt cagggtcgat catgatacga ccacagtatt
    15901 cgcaaacgat cactttctta cgcaacttga tatccaactg tttctggggc ggaatcttgt
    15961 tgaaacaacc accgcaggca ccacgctgta catatacgac agccaagccg ttacgtgccc
    16021 ccttgcggat acgtt
//
