LOCUS       c00369_gnlPro..        10845 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EKFCBCIP_369.
ACCESSION   c00369_gnlPro..
VERSION     c00369_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 11:40:06
            Original ID  :: gnl|Prokka|EKFCBCIP_369
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10845
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..684)
                     /locus_tag="ctg369_1"
                     /transl_table=11
                     /translation="MTDIESLCRLTEAVEAAGADIAPTYLEYVQLSFAIATDCGEAGRE
                     FFHRLCRVSPKYQREHAERVFSNALHTQRGEVHLGTAFHLAEATGVAISYVETVGTVRT
                     APQTLTQARAYNKVANEETDEETITEEKEELLSGSDPQHPLPTLPEANWPKLLQRIIKV
                     AKSEIQRDIMLMGAFTALGACMSRHVRCLYGGKYYYPSLQCFIVAPSASGKGILSYLRL
                     LVQPIH"
     protocluster    1..10845
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2457:7708]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2458..7708
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..10845
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10845
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(712..1341)
                     /locus_tag="ctg369_2"
                     /transl_table=11
                     /translation="MSNNYRMSYFMPPIAPIKDKQGRLMTPPTLIPFCEVSIEQVFQMI
                     TCNENLKTLTAQVRNATDIRAAKASLLPYVTPCGTFTRRSCKDFVSPSHLVIVDVDGLH
                     SYQEAVEMRRMLYDDPLLQPVLTFISPSGLGVKAFVPCHYSSTTNDVQNITDNMSWAMR
                     YVETAYNTVTAVSSETKSKVDFSGKDLVRSCFLSYDPEALFRTTNE"
     CDS             1512..1652
                     /locus_tag="ctg369_3"
                     /transl_table=11
                     /translation="MKKKTVCCSDLGAYINELLKRAKLKNEYVCETLGMGHDVLNGIKK
                     G"
     CDS             2025..2450
                     /locus_tag="ctg369_4"
                     /transl_table=11
                     /translation="MTNNTIKHLGIVENIQGSHLSVRIVQTSACAACSAKGHCSSADSK
                     DKIIDIIDTAASSYQVGEKVMVVGETSMGMMAVLLAFVLPFVLLIFSLFLLMALIENEL
                     YAALLSLAVLIPYYFVLWLNKTRLKQQFSFTIKPINN"
     CDS             2458..3411
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 38.1; E-value:
                     6e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg369_5"
                     /sec_met_domain="Fer4_7 (E-value: 1.5e-12, bitscore: 38.1,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 3.6e-09, bitscore: 26.3,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 7.4e-09, bitscore: 25.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 1.3e-08, bitscore: 25.4,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 3.1e-11, bitscore: 32.9,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.1e-06, bitscore: 17.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLILIAVISLGAIALVLAAILYVASKKFAVYEDPRIAQVGEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKFCPVGGQPVMAQIADILGLAAGEAEPMVAVV
                     RCNGTCMNRPRINQYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEAKCTACGACVKACPKAIIEIRPQGKKSRRVYISCVNKDKGAVARKACTVSCI
                     GCGKCVKTCPFEAITLENNLAYIDPHKCKSCRKCVEVCPQNTIIELNFPPRKPKEEAPA
                     APKPAAVSKEAVETPAPAAKVETPAEKATEAPKVTE"
     CDS             3436..4773
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg369_6"
                     /sec_met_domain="Fer4_10 (E-value: 1.5e-09, bitscore: 28.0,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 8.7e-17, bitscore: 50.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 2.6e-51, bitscore:
                     163.5, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 5.6e-30, bitscore: 93.4,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3e-06, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIITAEVPAKAVILLGQHIGAPAK
                     PVVAKGDVVKVGTKIAEPAGFVSAAIHSSVSGKVAKIDTIVDASGYAKPAIFIDVEGDE
                     WEETIDRSATLVKECELPAEEIVKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEIMVGVSILMKAVKVNKAFIGIENNKPDAIELMTKVASS
                     YAGIEVVPLKVKYPQGGEKQLIDAITKRQVASGALPISTGAVVQNVGTAFAVYEAVQKN
                     KPLFERVITVTGKSVAKPSNFLARIGTPMKQLIDACGGLPEDTGKVIGGGPMMGKALVN
                     IEVPTAKGSSGILIMNRKEAKRGEAQTCIRCAKCVSACPMGLEPYLLGALSENGDFETM
                     EKERIMDCIECGSCQFTCPANRPLLDYCRLGKGKVGAMIRARQAKK"
     CDS             4779..5771
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg369_7"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 1.8e-120,
                     bitscore: 391.7, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLIVSLSPHVHGGDSVQKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTATSVAACLFFEWAIGKYLMKKPTTTICDGSAIITGVLLAFNLPSNLPIWIIILGA
                     LFAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTSWPVVGQLTAYTDATTGATPL
                     ALMKQAIYGDTAALSQIPDALTLLIGQNGGCLGEVSALALLIGLVYMLWKKIITWHIPV
                     SILATVFVFAGIMHLADPEKYVSPVLQLLSGGLMLGAVFMATDYVTSPMSKKGMLIYGV
                     CIGLLTVVIRLFGAYPEGMSFAILIMNAFTPLINTYCKPKRFGEVAKKK"
     CDS             5798..6514
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg369_8"
                     /sec_met_domain="FMN_bind (E-value: 3.4e-23, bitscore:
                     72.2, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAISVALLAYVNELTKGPIAEANAKTLNEALKKVLPE
                     FTNNPVAESDTIFSEKDGKKNVDFIVYPAKNGEELVGTAVEAKSMGFGGELKVLVGFNA
                     EGKIYNYSLLAHTETPGLGSKADKWFGAYDPAKGEKAVSHEESTKSILGMNPGEAPLTV
                     SKDGGAVDAITASTITSRAFLNAVNAAYQAYKAEGGEVNGVTGASQKAKGADADAADAA
                     TGATIKVELTDSVSAK"
     CDS             6529..7113
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg369_9"
                     /sec_met_domain="Rnf-Nqr (E-value: 5.6e-71, bitscore:
                     228.1, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNFKVMMNGIIKENPTFVLLLGMCPTLGTTSSAINGMGMGLATM
                     FVLICSNVVISLIKNLIPDMVRIPSFIVVIASFVTLLQMVMQAYVPGLYATLGLFIPLI
                     VVNCIVLGRAEAFAAKNNAVASMFDGIGMGLGFTIALTLLGAVREFLGTGKIFDLTIMP
                     EEYGMLVFVLAPGAFIALGYLIALINSFKKA"
     CDS             7136..7708
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg369_10"
                     /sec_met_domain="Rnf-Nqr (E-value: 2.6e-63, bitscore:
                     203.1, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETAMGMSAAVA
                     FVLTIATIVTFLIQKFVLDVFGLGYLQTITFILVIAGLVQMVEIILKKVSPALYQALGV
                     FLPLITTNCCILGVAILVIQKDYDLLTGVVYAFSTAIGFGLALVLFAGLREQMSLVKIP
                     KGMQGTPIALITAGLLAMAFMGFSGVV"
     CDS             7933..8967
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg369_11"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 3.6e-52, bitscore:
                     167.7, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKERILVTGGTGYIGSHTVVELQNSGYEVIIIDNLSNSSADVVDN
                     IEKVSGIRPVFEKLDCLDFAGLDAVFAKYKGIKAIIHFAASKAVGESVQKPLLYYRNNL
                     VSLINLLELMPKHGVEGIVFSSSCTVYGQPDELPVTEKAPIKKAESPYGNTKQINEEII
                     RDTVASGAPINAIMLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAIGIREKLSVFG
                     DDYDTPDGSCIRDFINVVDLAKAHVIAIRRILEKTQKEKVEVFNIGTGRGVSVLELING
                     FEKATGVKLNYQIVGRRAGDIEKVWANPDFANKELGWKAVETLEDTLRSAWNWQLKLRE
                     RGIQ"
     CDS             complement(9085..9207)
                     /locus_tag="ctg369_12"
                     /transl_table=11
                     /translation="MLGVPKKRYHDSRRSTVTTQTQNKTRQNYYAIFPVYAGEA"
     CDS             9292..9591
                     /locus_tag="ctg369_13"
                     /transl_table=11
                     /translation="MRVVSHKKLKDFYETKGCEDSRVALERWYDIAEKAEWRNLSDIKA
                     DFLSTDYVGNQHYVFNIRGNNYRLVVVVKFTVGYIFVRWVGTHKEYDKIDCSTI"
     CDS             9602..9964
                     /locus_tag="ctg369_14"
                     /transl_table=11
                     /translation="MTKITKEQYEFALARVEELLPLVDDSTPANDKSMVELSVMSDIVI
                     AYEKEHFPIEKPTVAELIELSLEEKGMTQKQLASEIGVSPSRVNDYISGRSEPTLKIAR
                     LLCRVLNIHPAAMLGF"
     CDS             complement(9997..10827)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg369_15"
                     /sec_met_domain="GHMP_kinases_C (E-value: 1.1e-10,
                     bitscore: 31.9, seeds: 112, tool: rule-based-clusters)"
                     /sec_met_domain="GHMP_kinases_N (E-value: 1.1e-10,
                     bitscore: 31.7, seeds: 447, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLAFPNIKINLGLSITEKRPDGYHNLETVFYPVALEDALEIRTSS
                     ETEKKIILHQYGMEIAGNPEDNLVAKAYSLLDKEFHLPPVEIHLYKHIPSGAGLGGGSS
                     DAAFMLKLLNDHFQLELSEEQLEVYAATLGADCAFFIKNKPTYAEGIGNLFSPIELSLS
                     GYQIMIVKPNVFVSTREAFSNIHPHRPEYPVKEAILRPVAEWKDILINDFEASVFPQHP
                     VIGEIKEELYHQGAIYASMSGSGSSVFGLFAPGFVLPEIDWGTDVFCFKGTLNK"
ORIGIN
        1 atggatgggt tgcacgagca ggcggaggta ggagaggatg cctttgccgg aagcagaggg
       61 cgccacgatg aaacattgga ggctgggata atagtatttg ccgccataga ggcatcgcac
      121 gtggcgcgac atgcaagctc ccagcgcggt gaatgctccc atcagcatga tgtcgcgttg
      181 aatctcactt ttcgcaactt tgatgatacg ctgcaggagt ttcggccagt ttgcttccgg
      241 cagagtgggg agcgggtgtt gcggatcgct accggatagc agttcttctt tttcttccgt
      301 gatcgtttct tcgtctgttt cctcatttgc caccttatta tacgcgcgtg cctgtgtgag
      361 agtttgaggg gctgtcctta ctgtccccac tgtctccaca tagctgatgg cgactcccgt
      421 cgcttcggcc aggtggaaag cggtgcccag gtgcacttct ccgcgttggg tgtggagtgc
      481 gttggagaat acccgttcgg catgttcgcg ctgatacttg ggagagaccc ggcataggcg
      541 gtgaaaaaac tcacgtcctg cttcgccgca atccgttgcg atggcgaatg acaattgtac
      601 gtattcaaga taagtgggag caatgtccgc tcctgccgct tcgactgctt cggtgagacg
      661 gcataaagat tcaatatcag tcatttggat ttatgatttt tgatttatga tttattcgtt
      721 ggtggttctg aacaatgctt ccgggtcgta actaaggaaa caggatctca cgaggtcttt
      781 gccggagaaa tctactttgg attttgtttc ggaagaaact gctgttaccg tattgtatgc
      841 cgtctctacg taccgcatcg cccaactcat gttgtctgtg atattttgga catcatttgt
      901 cgtggaggaa taatggcagg gaacaaatgc ctttacaccc agtccgctgg ggctgataaa
      961 ggtgagtaca ggttgtagga gaggatcatc atagagcata cgtcgcattt ctactgcttc
     1021 ctgataagag tggagaccgt ccacatctac tatcaccaga tgagacgggg agacgaaatc
     1081 cttacagcta cggcgggtga atgtgccgca aggggtcaca tacggaagca atgatgcttt
     1141 ggcggctcgt atatctgtgg cattccgtac ttgtgcggtc agggttttga gattctcatt
     1201 gcaagtaatc atttggaaaa cttgttcgat ggagacttcg cagaagggga taagcgtggg
     1261 aggagtcatc agtcggcctt gtttgtcttt gatgggagcg ataggtggca taaaatagga
     1321 cattctgtag ttgtttgaca tcattttctt tttgttataa gttaaaatgt ttatttttgc
     1381 aaaaaatatg agtgtgtttc aaaaacacgg catgaaggta gtaataacaa aatagactct
     1441 accctgatat gtgaggataa aagttaaaat atttaattat taaagtgtgt atttaacaac
     1501 aaaaaacaaa gatgaaaaag aaaacggttt gttgcagtga tttgggagct tatattaatg
     1561 agttgcttaa acgtgcgaaa ttgaaaaatg agtatgtatg cgagaccctg ggtatgggac
     1621 atgatgtttt gaatggcata aaaaagggct aaatctccca ttgaacgatt atataaaagt
     1681 aatgaatctc tgtttgaatg cctacaacga agaggagatt gaactgattt tgaatacgtt
     1741 ggtgagaatg tatctgcgct actacaagaa gaggatagtg gagtaatccg tgaaataatt
     1801 gatagaaaat cccggctgaa taaataaaaa cggccgggat ttttttgttt aggatgtcta
     1861 tttgtcattc ttgggaaata tcaaatggta gccatacctt ttccgtgtgc gataacgaaa
     1921 acacaaaaaa taacatttta ttaggtagaa aaagtttgag gaatgcttcg tagttcacaa
     1981 ataatgatta aatttgccgc gatttgtaat gcggagtttg caaaatgacg aataatacta
     2041 taaagcatct aggtattgtg gaaaacatac agggttctca tctgtcggtg aggattgtcc
     2101 agacatcggc ttgtgcggca tgtagcgcaa aggggcattg ttcctcggcg gatagtaagg
     2161 acaaaatcat agatatcata gataccgcag cttcttccta tcaggtggga gagaaggtga
     2221 tggtggtcgg cgaaacgtcg atgggcatga tggcggtatt gttggctttc gtacttcctt
     2281 tcgtacttct tatattttcg ttgtttcttt tgatggcatt gatagagaat gaactgtatg
     2341 cagctcttct ttctctggct gtccttatac cttattattt cgttttatgg cttaacaaaa
     2401 cgcgactcaa acaacaattt tcatttacta taaaaccaat aaataactaa aaacattatg
     2461 aatttgattc tgattgcagt gatttcattg ggagctatag cgctcgtgct ggccgctatt
     2521 ctttatgtgg cttccaagaa atttgccgtg tatgaagacc cgcggattgc ccaggtggga
     2581 gaagtgcttc cccaggctaa ttgtggtgga tgtggctatc ccggttgtag cggctttgcc
     2641 gacgcttgcg tcaaagccgg ttcgctggat ggtaaattct gccccgtagg cggacagcct
     2701 gtcatggcac aaattgctga tatcctaggg cttgcagccg gagaagctga accgatggta
     2761 gcagtggtaa gatgtaacgg aacgtgtatg aatcgtccgc gtattaatca gtacgacggt
     2821 gcgaagagtt gcgctattgc cgcttcgctc tatggtgggg aaacgggttg tagttacgga
     2881 tgtctggggt gtggtgactg tgtggctgcc tgccagttcg atgccatcca catgaatcct
     2941 gaaacaggac ttccggaagt ggatgaagcg aaatgtaccg cttgcggtgc ctgtgtgaag
     3001 gcttgtccga aggcgatcat cgaaatccgt ccgcaaggaa agaaatcacg ccgtgtgtat
     3061 atctcttgtg tgaataaaga caagggagct gtggcacgca aggcttgtac ggtgagttgt
     3121 atcggctgtg gcaaatgcgt gaagacttgt ccgttcgaag ctatcacgtt ggagaacaac
     3181 ttggcttaca tcgatccgca caagtgcaaa tcttgccgga aatgtgtgga agtctgtccg
     3241 cagaatacca ttatcgaatt gaatttcccg ccgaggaaac cgaaagaaga agctccggct
     3301 gctccaaaac cggctgctgt ttctaaagaa gcggtggaaa ctcctgcacc ggcagcaaaa
     3361 gtggaaactc ctgctgaaaa ggctacagaa gctccgaaag taacagaata ataacagaat
     3421 aaaatacaga actgtatgtt aaagacattt tcaattggtg gagttcatcc acacgaaaat
     3481 aaattgtcgg cacatcaacc tattatcaca gcggaagttc ctgcaaaggc tgttattttg
     3541 ctggggcagc acattggtgc gcctgcaaaa ccggttgtag cgaaagggga tgtggtaaag
     3601 gtaggcacta agattgctga acctgccggc tttgtttcgg cagcaattca ctcttcggtc
     3661 agtggtaaag tggcgaagat tgatactatt gtcgatgcca gcggttatgc gaaacctgct
     3721 atctttatcg atgtggaagg cgacgaatgg gaagaaacaa tcgaccgtag cgccacactg
     3781 gtgaaggaat gtgaacttcc ggcagaagag atcgtgaaga aaattgccga tgccggaatc
     3841 gttggtctgg gcggtgcttg tttccctaca caggtgaaac tttgtcctcc tccttctttt
     3901 aaggctgaat gtgtgattat caatgctgta gagtgtgaac cttatttgac tgccgaccat
     3961 cagctgatgc tggaacacgc ggaagaaatc atggtaggcg tttctatcct gatgaaagcg
     4021 gtgaaagtga acaaggcatt tatcggaatc gaaaataata agccggatgc tatcgaactg
     4081 atgacgaaag tggcttccag ctatgcaggc atcgaagtag tgcccttgaa ggtgaaatat
     4141 ccgcaaggag gtgaaaagca gctgatcgat gcgatcacca aacgtcaggt ggcgagcggt
     4201 gcgttgccta tctctacggg agcagtcgtg cagaacgtgg gaacggcgtt tgccgtttat
     4261 gaagctgtgc agaagaataa accgttgttt gaacgggtga ttaccgtgac gggaaagtcg
     4321 gttgcgaagc cgtccaactt cctggctcgt atcggtacac cgatgaaaca gttgattgac
     4381 gcttgcggtg gtttgcccga agatacgggt aaggtgatcg gcggtggtcc gatgatgggt
     4441 aaggcgttgg taaatatcga ggttcctact gcgaagggca gttccggcat cctgattatg
     4501 aaccggaagg aagccaaacg tggtgaagct caaacctgca tccgttgcgc gaagtgcgtg
     4561 agtgcctgtc cgatgggact ggaaccgtac ttgctcggag ccttgtctga aaacggagat
     4621 tttgaaacaa tggaaaaaga aagaatcatg gattgtatcg agtgcggctc ttgccagttc
     4681 acttgtcctg ccaaccgtcc gctgctcgac tattgtcgtc tgggtaaagg caaagtggga
     4741 gctatgattc gtgcacgtca agctaaaaaa taacgaatat ggaaaataaa ttaatcgtat
     4801 cactatcgcc ccacgttcat ggcggagaca gcgtacagaa aaatatgtat ggcgtgctga
     4861 ttgcactgat tccggctttt ctggtgtctc tctatttctt cggactgggt gccctgattg
     4921 tcacggctac ttccgttgcg gcttgtttgt tcttcgaatg ggcgatcgga aaatatttaa
     4981 tgaagaaacc gaccaccacc atctgcgacg gctctgccat catcacaggt gtgttgctgg
     5041 catttaattt accgtctaac ctgcctatct ggattatcat cctcggtgca ctgtttgcta
     5101 tcggtgtagg taagatgtct ttcggcggat taggctgcaa tcctttcaac ccggcattgg
     5161 caggccgcgt attcctgctg ctttctttcc cggtgcagat gaccagctgg ccggtagtcg
     5221 gacagttgac cgcttatacg gatgctacca ccggtgccac tccgctggcc ttgatgaagc
     5281 aagccattta cggtgacact gccgctttaa gccagattcc ggacgcattg accttgctga
     5341 tcgggcagaa tggcggatgc ttgggtgaag tgagtgcgct ggctctgctg atcggactcg
     5401 tttatatgct ctggaagaaa atcatcacct ggcatattcc tgtgtctatc ctggctactg
     5461 tgtttgtctt tgcaggcatc atgcacctgg cagatccgga aaaatacgtt tctccggtat
     5521 tgcagttgct ttccggtggt ctgatgctgg gtgctgtctt tatggcaacc gactatgtga
     5581 cttctccgat gagtaagaaa gggatgctga tctatggtgt atgtatcggt ctgctgacgg
     5641 tagttatccg tctgttcggc gcctatcccg aaggtatgtc gttcgccatc ctgattatga
     5701 atgcgttcac tccgctgatt aacacctatt gtaaaccaaa acgctttggg gaggtagcga
     5761 agaagaaatg aaaaagttag aatcatcttt aaagaatatg ttgctggtac ttacgggagt
     5821 gactgctatt tccgttgcgt tgctggctta tgtaaatgaa ctgacaaaag gccccattgc
     5881 cgaagcgaac gcgaagacac tgaacgaggc cttgaaaaag gttcttcccg aatttaccaa
     5941 taatccggta gcggaaagcg atacgatctt cagtgagaaa gacggaaaga agaatgttga
     6001 ctttatcgtt tatccggcta agaacggtga agagcttgta ggtacggctg ttgaagctaa
     6061 atcaatggga tttggcggtg aactgaaagt gctggtaggc tttaatgccg aagggaaaat
     6121 ctataactac tctctgttgg ctcacacgga aactccggga ttgggctcta aagccgacaa
     6181 atggttcgga gcgtatgatc ctgcgaaagg agaaaaggca gtatctcacg aagagagtac
     6241 gaaatctatt ttgggtatga atccgggtga agctccgttg accgtcagta aagatggggg
     6301 agcagtggat gccatcacag cttctaccat tacttcacgc gctttcttga atgccgtgaa
     6361 tgctgcttat caagcctata aggccgaagg cggggaagtg aatggggtaa ccggtgcttc
     6421 tcaaaaagcg aaaggcgcgg acgcagatgc tgctgacgct gctacgggag ctacgatcaa
     6481 agttgaacta actgattcag tcagtgctaa ataagaaagg agacagatat gaataacttt
     6541 aaagtaatga tgaacgggat tatcaaagag aatcctacgt ttgtactcct gctcggtatg
     6601 tgtcctacat tgggtactac atcatcggct atcaatggta tgggcatggg actggctacc
     6661 atgttcgtat tgatctgctc gaatgtggtg atctctttaa taaagaacct gattccggac
     6721 atggtgcgta tcccatcgtt tattgtggtg attgcgtctt tcgtgacctt gcttcaaatg
     6781 gtgatgcagg cttacgtgcc gggactgtat gctacactcg gtcttttcat tccgttgatt
     6841 gtagtgaact gtattgtact gggacgtgcc gaagccttcg ctgccaagaa taacgcagtt
     6901 gcttctatgt tcgacggtat cggtatgggg cttggcttta ccatcgccct gactttactg
     6961 ggtgctgtcc gcgagttttt gggaaccggt aaaatcttcg atttgaccat catgccggaa
     7021 gaatatggaa tgttggtgtt tgtattggct ccgggcgctt tcatcgcttt gggatacctc
     7081 attgcgttga ttaacagttt caagaaagcc taattcaatt aaataagaaa agaatatgga
     7141 atatatattg atatttattt cggcaatctt tgtaaacaac atcgtgttgt cgcagttcct
     7201 gggtatctgt ccgttcctgg gcgtatccaa gaaggtggaa actgcgatgg gtatgagcgc
     7261 tgcggttgct ttcgtgttga ccatcgctac catcgtcact ttcctgattc agaaatttgt
     7321 actggatgtt ttcggactgg gatacttaca gacgattaca tttatcctgg tgattgccgg
     7381 attggtgcag atggtggaaa tcatcctgaa aaaggtatct ccggccctgt atcaggcttt
     7441 gggtgtgttc ttgccgctga ttacaacgaa ctgttgtatt cttggtgtcg ctatcctggt
     7501 gattcagaaa gactatgacc tgctgacagg tgttgtatac gcattctcta cggctatcgg
     7561 cttcggtctg gcactggtgc tttttgccgg attgcgcgaa cagatgagcc ttgtgaaaat
     7621 tccgaaagga atgcaaggaa ctccgattgc tttgattacc gccggtttgc ttgctatggc
     7681 attcatggga ttctccggcg tggtgtaagg atttacagtt gatgattaaa taggggattg
     7741 gaagctctgc tgtgtggcga catacaggtt agagtttcca attctttttt atacctaaat
     7801 gctaccaaat cgtaccttaa ttacttttca gcaaataaat ttgtggcaga ttattgcaat
     7861 ttcattttat ttccatacat ttgtaactca aacaataata agccgagaaa ctaaccattt
     7921 tttataaagt atatgaaaga aagaatttta gtaacaggcg ggacaggata cattgggtct
     7981 catactgttg tagaactaca aaacagtgga tatgaagtaa tcatcatcga taatttatca
     8041 aattcaagtg ccgacgttgt tgacaatata gagaaagttt ccggtattcg cccagttttt
     8101 gaaaagctgg actgtttgga ctttgccggt ctggatgcag tatttgcaaa atataaagga
     8161 attaaggcaa tcattcactt tgcagctagc aaagcagtag gagagtcggt acaaaaaccg
     8221 ttgctttact accgtaataa cctggtttct ttgattaacc ttctcgaact gatgccaaaa
     8281 catggagtag aaggtattgt gttctcttct tcttgtacag tatacggtca gccggacgag
     8341 ctgccggtaa cggaaaaagc tccgatcaag aaagcggaat caccttatgg aaataccaaa
     8401 cagatcaatg aagagattat tcgtgatacg gtagcttcag gtgctccgat caatgcgatc
     8461 atgttgcgct atttcaaccc gattggcgcg catcctactg cattgcttgg tgaactgcct
     8521 aacggggttc ctcaaaacct gattccatat ctgacccaga cagccatcgg tatccgtgag
     8581 aaacttagcg tgtttggtga cgattatgat acaccggacg gttcttgtat ccgtgacttt
     8641 atcaatgtcg ttgacttggc taaagcacac gtgattgcta tccgtcgtat cttggaaaag
     8701 acacaaaaag aaaaagtaga agtatttaat attggtacag gacgtggtgt ttctgtattg
     8761 gaattaataa atggctttga aaaagccact ggcgtaaaat tgaattatca gattgtcgga
     8821 cgtcgtgcag gcgacattga aaaagtttgg gctaacccgg attttgctaa taaagagctg
     8881 ggttggaaag ccgtagaaac tttagaagat actttacgct ctgcatggaa ctggcagctg
     8941 aaactccgtg aaagagggat tcaataaaag agaaacttgt tttaaataac ataaaagttt
     9001 aaacaaatcg tgcatgcgat ttgtttaatt gatgctaatc gacctgaagc tgtttatgag
     9061 tatgcgaata tacgtagata gtacttatgc ctccccggca tagacaggaa agattgcata
     9121 gtagttttgt cgtgttttat tttgtgtttg tgttgtgacg gtactacgac gtgagtcgtg
     9181 gtaccgtttt tttggtacgc ccagcatgga tgttctgttt tataaaatat ttagcactaa
     9241 ttcttttgtt atccaaaatt attttgtaat tttgtatcaa atgaataaga tatgagagta
     9301 gtatcacata agaaattgaa agatttctac gagacgaaag ggtgtgaaga ttcacgtgtt
     9361 gctttagaac gttggtatga tatagcggaa aaagcagaat ggcggaattt gtctgatata
     9421 aaagcggatt ttctatcgac tgattatgtg ggcaatcaac actatgtttt taatatcaga
     9481 gggaacaact atcggctggt agtggttgtt aaatttacgg tgggatacat ttttgtccgt
     9541 tgggtgggaa ctcataaaga gtatgataaa atagattgtt caactatata atataataga
     9601 tatgactaaa ataacgaaag aacaatacga atttgcattg gcaagagtcg aagaacttct
     9661 gcctttggtg gacgacagca ctcctgcaaa tgacaagagc atggtggagc tttctgttat
     9721 gtctgatata gtgattgcgt atgagaagga acattttcct atagaaaaac caaccgtagc
     9781 agaattgata gaattgtccc ttgaagaaaa ggggatgaca caaaaacagc ttgccagtga
     9841 aataggggtt agcccttcac gcgtgaatga ttatatttcg ggtcgctcgg aacctacttt
     9901 aaaaatagct cgcttgcttt gccgggtact caatatacac cccgctgcca tgttgggatt
     9961 ttgaaaaaat agtcaaaaca taattgttag tgagatttat ttgtttaatg tacctttgaa
    10021 gcagaatacg tcagttcccc aatcaatttc cggtaagacg aatccgggag caaacagccc
    10081 gaatacggat gagccggagc cgctcatgga tgcgtagatt gctccttgat gatagagttc
    10141 ttctttgatt tctccaatga cgggatgttg cgggaataca cttgcttcga aatcattgat
    10201 taggatatcc ttccattctg caactggacg caggattgcc tctttgaccg gatattccgg
    10261 acggtgcggg tggatatttg aaaaggcttc ccgggtagaa acgaaaacgt tcggcttgac
    10321 gatcatgatt tggtaaccgc ttaatgaaag ctcgattggt gagaacaggt ttccgatccc
    10381 ttcggcatag gtcggcttgt ttttaataaa gaaagcacag tccgctccca aagtggcggc
    10441 atatacctcc agctgttctt cagataattc cagctgaaaa tgatcattga gcaacttcag
    10501 cataaaagcg gcatcggatg aaccgccccc cagtccggct cccgagggaa tatgcttata
    10561 taaatgaatt tcgacagggg gaagatgaaa ctccttatcc agcaatgaat aggcctttgc
    10621 caccaggttg tcttccggat tgccggctat ctccatgcca tactggtgga ggataatctt
    10681 cttttctgtt tcagaagaag tacggatttc gagagcgtct tcgagggcta ccggatagaa
    10741 aacggtttcc agattgtgat atccgtccgg gcgtttttcc gtgatggaaa gtcccaggtt
    10801 tattttgata ttaggaaaag cgagcataag gttatttact atttt
//
