LOCUS       c00080_gnlPro..        15374 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BHKNFCMO_80.
ACCESSION   c00080_gnlPro..
VERSION     c00080_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 11:21:57
            Original ID  :: gnl|Prokka|BHKNFCMO_80
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15374
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15374
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2552:5374]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2553..5374
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..15374
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15374
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(2..235)
                     /locus_tag="ctg80_1"
                     /transl_table=11
                     /translation="MIFLCIGSHLAEARSLAGKHVDIIHLEVYLCFVSNSQQVKNRIGR
                     SPHCYIQRHGVQESLTGSDATGKYTFVSFFII"
     CDS             complement(446..1162)
                     /locus_tag="ctg80_2"
                     /transl_table=11
                     /translation="MTVENEWFTIIALSAAQLTITYQLSPTILYNSHCSLIGRAYHAGI
                     RLQALWYITVTSDRSHRTGCQFFIRQSHVNLPGRNIDFDNVSVYNFSDIASSCRFRRNM
                     SDTQSGSSTAETSVGNQSTFFSEMTGFYIRGRIKHFLHTGTTLRTFVRDDDDVSTDDST
                     SEDAFTSCFLRIKYFGRSGKLPDTFVYTCCFYYTTVLSNIAFQYGQSAVFTVSMFQVTD
                     TSVCTVLIQFLIVHTL"
     CDS             complement(1212..2552)
                     /locus_tag="ctg80_3"
                     /transl_table=11
                     /translation="LQSAISHKYAYGTFRCSESCPDSCGKPEAHCSKSSGSNDTAFFRI
                     FKVTCRYHLILTYICYQNSFMVSSVTYRTYHFPHAQRVCGRMKFRTDYFFLLYFLIFFE
                     AINPFGMSVLFQEFRHRSQCFLAISQYSYIYLYILINFRRIDIKMNHFCLFGISSQITG
                     HTVVKTHTDSNQHIAFIGIDIRSQIAVHTQHTFIQRMFCRQSRKPEQRTTRRHIRFFDK
                     LAQFALCISQFNTLSNQYKRTFSVINQFGSSLYRLLVHIGNRNIATDKIDFRRFVFRFL
                     YLRIFGKVQYHRPRTTTTSNVKRTCYRPGYIFRTANLITPFSDWLGDTYQVNFLKSIRP
                     KKACSYLSGNHHDRRTIDHRICNACYRIGCSGTARHQANTYITRYTGITLCGMGSSLFV
                     TNQDMVQYILMIVQGIEYRHNRATGVTKDGSHSLMFQGAHQSLCTCY"
     CDS             2553..2897
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 7e-24, bitscore:
                     75.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIQELGTIMEQKAPVKIICLNNNYLGNVRQWQAMFFNRRYSFTP
                     MLNPDYMKVASAYDIPSKRVFTREELKEAITEMLATDGPFLLEACVVEEGNVLPMTPPG
                     GSVNQMLLEC"
     CDS             2955..3512
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_5"
                     /sec_met_domain="ALS_ss_C (E-value: 5.5e-19, bitscore:
                     59.1, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDKTLYTIIVHSENIAGLLNQVTAVFTRRQINIESLNVSASSIK
                     GVHKYTITAWTDKDIIEKVVKQIEKKIDVIQAHYFTEDEIYFHEIALYKVSTPAFQENP
                     EASKLIRRYNARIVEVNPVFSIVEKNGMSEDITSLYGELKALNCVLQFVRSGRVAITTS
                     CFERVNEFLDGREAMYNQSKNQ"
     CDS             3518..4261
                     /locus_tag="ctg80_6"
                     /transl_table=11
                     /translation="MSEENRIGTYQFVAEPFHVDFNGRLTMGVLGNHLLNCAGFHANDR
                     GFGIATLNEDNYTWVLSRLAIELDEMPYQYENFSVQTWVENVYRLFTDRNFAILDKDGK
                     KIGYARSVWAMINLNTRKPADLLTLHGGSIVDYVCDEPCPIEKPSRIKVTSDQPIATLT
                     AKYSDIDINGHVNSIRYIEHILDLFPIELYKTKRIRRFEMAYVAESYFGDELSFFCDEV
                     NANEFHVEVKKNGNEVVCRSKVIFE"
     CDS             4331..5374
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_7"
                     /sec_met_domain="IlvN (E-value: 1.9e-46, bitscore: 148.5,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.8e-41, bitscore: 132.7,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGTTETVVIRDEFPLEKAREVLKNETIAVIGYGVQGPGQ
                     ALNLRDNGFNVIVGQREGKTYDKAVADGWVPGETLFGIEEACEKGTIVMCLLSDAAVMS
                     VWPTIKPYLTAGKALYFSHGFAITWNDRTGVVPPADIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAIYQDATGKAYERTIALGIGIGSGYLFETTFQREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHSPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMG
                     PFHDAIKPVVEKLYNSVKTGNEAQISIDSNSQPDYREKLNEELRQLRESEMWQTAVTVR
                     KLRPENN"
     CDS             5977..7527
                     /locus_tag="ctg80_8"
                     /transl_table=11
                     /translation="LYKTKVVGSDVSAKITFENVLDVTPVDSSTRSAQTRAAVKFITDV
                     IPNVLGTWNANSGKPDYLDASKKINVDATLKSYITTYFPEGKNNVGPLVTDNADILIKE
                     DANVVINYFGGDTGAKSVFAYYCYPKDASTDEIRKATKHACVIFPNAHGNSLGYYSGVA
                     VNLKYINETGNFPQKDPERIPANTKIGFLIWNNGWVNAKANGNMFYSTKSLNSDKISHT
                     AIFAAKNKAGDRVNVITMEDWKNGENDYNDVAFVISSNPIAAIEVPDVPNPGDRQGTEM
                     YSGVLGFEDNWPEQGDYDLNDVVMKYQSSVDYNIDNKVLNIIDKFTLAWTGANYKNSFA
                     YEVPFDLSKASKVTVNGSEASSYSGNVITLFKDAKAELGVSNVNAEDMINQNIQEKTYT
                     VSIQFNNPTLDKSVVVAPYNPFIKVFNSATEVHLTDHKPTTGANNRFPSGADISRGDVD
                     GTYFICKDGFPFAIHVDARLDASILNLDLKKENQRIDKTYPKFAEWAKTRDPQIKWWK"
     CDS             complement(7671..8603)
                     /locus_tag="ctg80_9"
                     /transl_table=11
                     /translation="MSRLRDRATELEIQINADLFDSARVIASTLVSSNHRLLNGRRFST
                     LFIDEAAQALEAACWIAIRKADRVILAGDHCQLPPTIKCIEASRGGLDHTLMEKVVQQK
                     PSAVSLLKVQYRMHEAIMQFPSDWFYHGELEAAPEVRYRGILDFDTPMNWIDTSEMDFH
                     EDFVGESFGRINKQEANLLLQELETYIERIGKKRILDERIDFGLISPYKAQVQYLRGKI
                     KGSSFLRPFRSLITVNTVDGFQGQERDVIFISLVRANEDGQIGFLNDLRRMNVAITRAR
                     MKLVILGDASTLTKHPFYKRLMLFIKKED"
     CDS             complement(8798..8944)
                     /locus_tag="ctg80_10"
                     /transl_table=11
                     /translation="MYLLFTVLREPERQRLLSKRFTKHCTGNHKCLFVRKATRLSTGFV
                     RNW"
     CDS             9321..9653
                     /locus_tag="ctg80_11"
                     /transl_table=11
                     /translation="MLYFFIFGPCNIYYKLIQRIVVTSTKRDRIPAETALHFTGNAHCF
                     GLPLKFFLLIFILHPQEELLLLKVYNGTFRIITHNRRKGNKSSFRVEKIFHFVKHYSNV
                     VRYFNR"
     CDS             complement(9696..10160)
                     /locus_tag="ctg80_12"
                     /transl_table=11
                     /translation="MRVCSHHHTAGESIVFEHHLMDNSCSRFPEADAITGRYITEEVVY
                     FFISQSCRSNIRLCTFIRLYQMIAMYCRRHSHLILTCIHKLKQSHLRSCILHSHTVGTE
                     IHIILPPFVIFQIGYIIQMSIQNFLGQRQRAFQYSPYVFYLSFISSVESF"
     CDS             complement(10504..10653)
                     /locus_tag="ctg80_13"
                     /transl_table=11
                     /translation="MARLYKVRVLTSLFQLHGRNSWMVRWSQCRLHEGLHQQIQPNRLH
                     NLFR"
     CDS             complement(11340..11696)
                     /locus_tag="ctg80_14"
                     /transl_table=11
                     /translation="LFFQVCFVDTGKTLSQNDTYIEEAWFHGCMFTAGTFSIILFGNNN
                     RRNTFGLIHLCRTGNCSISICRTIPNTVRFTIENIDSSHQHIVGNILQMSTEAEPRTCH
                     RDMVGSTFSLCFNQ"
     CDS             12153..13118
                     /locus_tag="ctg80_15"
                     /transl_table=11
                     /translation="METFQEYLVGIKGPLTTPVGGGIRSLNVALRQTLDLYVCLRPVRW
                     YQGVQSPVKSPEKVNMCVFRENTEDIYAGIEWEAGTPEAEKFYQFLKDEMGVTKVRFPE
                     TSSFGVKPVSREGTERLVRAACQYALDHHLPSVTLVHKGNIMKFTEGGFKKWGYELAQR
                     EFGDALADGRLVIKDCIADAFLQNTLLIPEEYSVIATLNLNGDYVSDQLAAMVGGIGIA
                     PGANINYQTGHAIFEATHGTAPNIAGKDVVNPCSIILSAVMMLEYFDWKEAAALIEKAL
                     EQSFLDARATHDLARFMPNGTSLSTSAFTREIVERIEKQK"
     CDS             13139..14482
                     /locus_tag="ctg80_16"
                     /transl_table=11
                     /translation="MKKEYLIYKLSEEMKEATRIDTELFSKFDVKRGLRNEDGTGVLVG
                     LTRIGNVVGYERVPGGGLKPIPGKLFYRGYDVEDISHAIIKEKRFGFEEVAYLLLSGRL
                     PDKEELLSFRELINDNMPLEQKTKMNIIELEGNNIMNILSRSVLEMYRFDANADDTSRD
                     NLMRQSIELISKFPTIIAYAYNMLRHATFGRSLHIRHPQEKLSIAENFLYMLKKDYTEL
                     DARTLDLLLILQAEHGGGNNSTFTVRVTSSTGTDTYSAIAAGIGSLKGPLHGGANIQVA
                     DMFQHLKENIKDWTSVDEIDTYYTRMLNKEVYNKTGLIYGIGHAVYTISDPRALLLKEL
                     ARDLAREKGRESEFAFLELLEERAIATFGRVKNNGKTVSSNIDFYSGFVYEMIGLPQEI
                     FTPLFAMARIVGWCAHRNEELTFDGKRIIRPAYKNVLDDLAYIPIKKR"
     CDS             complement(15095..15190)
                     /locus_tag="ctg80_17"
                     /transl_table=11
                     /translation="MGRGASSSKEAMSRISRESPEYAFICSELRA"
ORIGIN
        1 attatattat gaagaaggag acgaaagtgt acttccccgt agcatcgcta cccgtcaggc
       61 tttcctgaac gccatgacgc tggatatagc aatgggggga tctaccaata cggttcttca
      121 cttgttggct gttgctcacg aagcagaggt agacttcaag atggatgata tcgacatgct
      181 ttcccgcaag gctccttgcc tctgcaaggt ggctcccaat acacagaaat atcatattca
      241 ggatgtaaac cgtgccggtg gtatcattgc cattatggac gaactggcaa agggcggttt
      301 gatagataca tccgttcgcc gggtagacgg aatgtcactg gcagaagcta ttaatgaata
      361 ttcaatcacc agcccgaatg tgagcgaaaa agcaattaag aaatattcga gcgcagccgg
      421 aaataaattc aatctcgtac ttggttcaca aggtatgtac tataaggaac tggataagga
      481 ccgtgcaaac ggatgtatcc gtgacttgga acatgcttac agtaaagacg gcggactggc
      541 cgtattgaaa ggcaatattg ctcaagacgg ttgtgtagta aaaacagcag gtgtagacga
      601 aagtatctgg aagtttaccg gacctgccaa agtatttgat tcgcaagaag cagcttgtga
      661 aggcatcctc ggaggtcgag tcgtcagtgg agacgtcgtc gtcatcacgc acgaaggtcc
      721 gaagggtggt cccggtatgc aggaaatgct ttatcctacc tcttatataa aatcccgtca
      781 tctcggaaaa gaatgtgctt tgattaccga cggacgtttc agcggtggaa cttccggatt
      841 gagtatcgga catatttctc ctgaagcggc agctggaggc aatatcggaa aaattgtaga
      901 cggagacatt atcgaaatcg atattccggc ccggaagatt aacgtgcgac tgacggatga
      961 agaactggca gcccgtccga tgactcctgt cactcgtgac cgttatgtac caaagagcct
     1021 gaaggcgtat gccagcatgg taagctctgc cgataaggga gcagtgagaa ttatataata
     1081 tagttggtga tagttgatag gtaatagtta gctgcgcagc acttagcgca atgattgtaa
     1141 accattcatt ttcaactgtc atttctcaac tatcatttat catttatcaa ctatcaacta
     1201 atatgaaaga tttaataaca ggtgcagagg ctttgatgcg ctccttggaa catcagggag
     1261 tgactaccat ctttggttac cccggtggct ctattatgcc ggtattcgat gccttgtacg
     1321 atcatcaaaa tatattgaac catatcttgg ttcgtcacga acagggagct gcccatgccg
     1381 cacaaggtta tgcccgtgta tcgggtgatg taggtgtttg cctggtgacg agcggtcccg
     1441 gagcaaccaa tacggtaaca ggcattgcag atgcgatgat cgatagtacg cctatcgtgg
     1501 tgattgccgg acaggtagga acaggctttc ttgggacgga tgcttttcag gaagttgact
     1561 tggtaggtat cacccagcca atcactaaat ggagttatca gattcgccgt gcggaagatg
     1621 tagcctgggc ggtagcacgt gcgttttaca ttgctcgtag tggtcgtccg gggccggtgg
     1681 tactggactt tgccaaaaat gcgcaagtag agaaaacgaa atacgaaccg acgaaagtcg
     1741 attttatccg tagctatgtt cctgttcccg atatggacga ggagtctgta caggctgctg
     1801 ccgaactgat taataacgct gaacgtccgc ttgtattggt tggacaaggt gttgaactgg
     1861 gaaatgcaca gagcgaattg cgcgagttta tcgaaaaagc ggatatgcct gcgggttgta
     1921 cgctgctcgg gctttcggct ttgccgacag aacatccgtt gaataaaggt atgttgggta
     1981 tgcacggcaa tctgggaccg aatatcaata ccaataaatg cgatgtgctg attgctgtcg
     2041 gtatgcgttt tgacgaccgt gtgaccggta atttggctac ttatgccaaa caggcaaaag
     2101 tgattcattt tgatatcgat cctgcggaag ttaataagaa tgtaaaggta gatgtagctg
     2161 tattgggaga ttgcaaggaa acactggctt ctgtgacgaa actcctgaaa aagaacactc
     2221 ataccgaatg gattgatagc ttcaaagaat atgagaaagt agaggaggaa aaagtaatcc
     2281 gtcctgaact tcatcctgcc acaaactctt tgagcatggg ggaagtggta cgtgcggtaa
     2341 gtgacgctac tcaccatgaa gctgttttgg taacagatgt aggtcaaaat cagatgatat
     2401 ctgcacgtta ctttaaatat acgaaagaac gcagtatcat tacttccgga ggacttggaa
     2461 caatgggctt cgggcttccc gcagctatcg gggcaacttt cggagcaccg gaacgtaccg
     2521 tatgcgtatt tatgggagat ggcggactgc aaatgaatat tcaggaactg ggtacgatta
     2581 tggagcagaa ggctccggtg aagattatct gcctgaacaa taattacctc ggaaacgtac
     2641 gtcagtggca agctatgttt ttcaaccgtc gctattcgtt taccccgatg ttgaatccgg
     2701 attatatgaa agtggcctcg gcttatgata ttccttccaa gcgtgttttc actcgtgaag
     2761 aactgaagga agctattact gaaatgctgg caacggacgg accgttcctg ctcgaagctt
     2821 gcgtggtgga agaaggcaat gttttgccga tgactcctcc gggtggttcg gtaaaccaga
     2881 tgttgctgga gtgctaggag aagttgagag ttgagaatgg agagttgaga gttcgcattt
     2941 aaaaaattag agttatgagt gataaaacgt tatatacaat cattgttcat tcggagaata
     3001 tagccgggtt gctgaatcag gtaactgctg tatttacccg tcggcaaata aatattgaga
     3061 gtctgaatgt atctgcttct tctattaaag gtgtacataa gtatacaata acagcctgga
     3121 ctgataagga catcattgag aaggtagtga aacagatcga aaagaagatc gacgtgattc
     3181 aggcacatta tttcacagag gatgagattt atttccacga gattgcatta tataaggtgt
     3241 ctactcctgc ttttcaggag aatccggaag catccaagct gattcgtaga tacaatgcac
     3301 gtatagtgga agtcaatccg gtattttcta ttgtcgagaa aaatggaatg agcgaagata
     3361 taacttcgct ctatggtgaa ctgaaggctt tgaattgtgt tttgcagttt gttcgttcgg
     3421 gacgtgtagc gattactacc agctgctttg aacgggtgaa tgagtttctc gatggacggg
     3481 aagctatgta taaccaaagt aaaaaccaat aagaataatg agtgaagaaa atagaatagg
     3541 gacttatcag tttgtggcag aaccgttcca tgttgacttc aacggacgtt tgaccatggg
     3601 ggtactggga aatcatctgc tgaattgtgc aggttttcac gccaatgacc gtggttttgg
     3661 tattgcaacg ctgaatgagg acaattatac atgggtgctt tcacgtctgg ctattgagtt
     3721 ggatgaaatg ccttatcagt atgagaattt ctcggttcag acgtgggtgg aaaatgtcta
     3781 ccgtttgttt acggaccgta attttgctat cctcgataag gatggaaaga agattggcta
     3841 cgcacgttcc gtatgggcaa tgattaatct taatacccgc aagcctgccg acttgttgac
     3901 tttgcatggg ggaagtatcg tagactatgt ctgtgatgag ccttgcccga ttgaaaagcc
     3961 ttcacgcatc aaagtgacaa gcgatcagcc gatagctacc ctgacggcaa aatacagtga
     4021 tatagatatc aacggtcatg taaacagcat ccgttacatc gagcatatcc ttgatttgtt
     4081 cccgattgaa ttgtataaga ccaaacgtat ccgtcgtttt gaaatggcgt atgtggcgga
     4141 aagctatttt ggtgatgaac tctctttctt ctgcgatgaa gtgaacgcaa acgagtttca
     4201 cgtagaagtg aagaagaatg gcaatgaagt tgtttgccgc tcgaaagtga tatttgaata
     4261 aatgtgagaa tataaaatca attaataaca cagatggcgt aagtcatcaa aaactaaaaa
     4321 caaaaagaaa atggcacagt tgaattttgg aggtactact gaaactgtag taatccgtga
     4381 cgaatttcca ttggaaaaag ctcgtgaagt attgaaaaat gaaacaatcg ctgtaatcgg
     4441 ttatggcgta cagggtcctg gacaggcact gaacttgcgt gataacggtt tcaatgtaat
     4501 cgttggtcaa cgtgaaggaa aaacatacga taaggcagta gcagacggat gggttccggg
     4561 tgaaactttg ttcggtatcg aagaagcttg tgagaaaggt actattgtaa tgtgtctgtt
     4621 gtctgacgca gcagtaatgt cagtatggcc tactatcaag ccttacctga ctgccggaaa
     4681 agctctttat ttctcacacg gttttgctat cacttggaac gaccgtacag gtgtagttcc
     4741 tcctgctgat atcgacgtta tcatggttgc tcctaaaggt tcgggtacat ctttgcgtac
     4801 tatgttcctc gaaggacgcg gcttgaactc ttcttatgct atctatcagg atgctacagg
     4861 caaggcttac gaaagaacca tcgcactggg tattggtatc ggttccggtt atctgttcga
     4921 aacaactttc caacgtgagg ctacttctga cctgacaggt gaacgtggtt cattgatggg
     4981 ggctatccaa ggtttgttgc tggcacagta cgaagtattg cgtgaaaacg gtcatagtcc
     5041 ttctgaagca ttcaatgaaa cagtggaaga actgacacag tcattgatgc cgttattcgc
     5101 aaagaacggt atggactgga tgtacgctaa ctgctctact actgctcaac gtggtgctct
     5161 cgattggatg ggcccattcc acgatgctat caaaccggta gttgaaaagt tgtataatag
     5221 cgtgaagact ggtaacgaag cacagatttc tattgatagt aattcacaac ctgattatcg
     5281 tgaaaagtta aacgaggagc tccgtcaatt acgcgaaagc gaaatgtggc agactgctgt
     5341 aactgttcgt aaacttcgtc cggagaataa ttaattagac cagattatac aagttttaaa
     5401 agaaggagag agctttttgc tttctccttc ttttattaat aagatattta aaaatgggta
     5461 ggtgaagctt gcagaaactt ttttttgaaa aatatatcaa taatgtgatt aaaatatgca
     5521 agtttatgtt tatatttgca ctatcaaata aaatgaacga gaagtatgat gtgttttaac
     5581 ttaccccaaa gaatgattaa cattgctaaa ttagcatgtg ttatcagtgt tgtttctgtt
     5641 gctttctcaa gctgtttaca gaaagatgta tatgatcctg ctaattcagg agataaagaa
     5701 gaagttactt tagataacta tttcgacttt gccactacta aaaatattca attgaatatt
     5761 gattatggaa aggaatgtcc tagggcttat tttgaagttt atgctgaaaa tccgctttct
     5821 tatgtggcag aaggcggtca gattataaag aaagcagggg tgtcacacat tgcaaccgga
     5881 tttacagata tacaaggacg ttatatcaaa ccggcttctt tcccgacagc agtttcagaa
     5941 gtttatattt attctccgga ttttggtgtg ccgactttgt ataaaactaa agttgtcggt
     6001 tcggatgtca gcgcaaaaat aaccttcgag aatgttcttg atgttactcc tgtggattca
     6061 tcaacgagaa gtgcacaaac aagggctgcg gtgaaattta ttacagatgt aatcccgaac
     6121 gtattaggaa cttggaatgc aaattcaggt aagcctgact atttggatgc ttctaagaag
     6181 atcaacgtgg atgcaactct caagagttat ataacgacat attttccgga aggaaagaat
     6241 aacgtaggac ctttagttac tgataatgct gatattctga taaaagaaga tgcaaatgtc
     6301 gttattaact attttggggg agacacagga gcgaaaagtg tatttgctta ttattgctat
     6361 ccgaaagatg cttctactga tgaaataagg aaggcaacaa agcatgcatg tgtcatattt
     6421 cctaacgcac atggaaatag tttaggttat tatagtgggg ttgcagttaa tttaaaatat
     6481 ataaatgaga ctggtaattt ccctcaaaag gacccggaac gtattccggc aaatacaaag
     6541 attggtttct tgatatggaa taatggctgg gtaaatgcca aggctaatgg gaatatgttc
     6601 tactcaacca aatctttgaa tagtgacaaa atttctcaca ctgcaatttt tgcagcaaaa
     6661 aataaagcag gtgatagagt gaatgttatc actatggaag actggaaaaa cggtgaaaat
     6721 gactataatg atgttgcttt cgttatctct tctaatccta ttgctgctat tgaagttccg
     6781 gatgttccta atccgggtga tcgacaagga acagaaatgt attctggagt gcttggcttt
     6841 gaagataact ggccggaaca aggagattat gacttgaatg atgtagtcat gaaatatcag
     6901 tcaagcgttg attataatat agataataag gttcttaata ttattgataa gttcaccttg
     6961 gcttggacgg gagctaatta taagaactcg tttgcttatg aagttccttt cgatttgagt
     7021 aaagcttcta aagtaacggt taatggtagt gaagcttctt cctattcagg taatgtgata
     7081 acattattca aggatgctaa agctgaattg ggagtatcca atgtgaatgc ggaggatatg
     7141 attaatcaga atattcaaga gaagacatat acggtatcca tacaatttaa taatcctact
     7201 cttgataaat cagtggtggt agctccttat aatcctttta taaaagtatt caactctgcc
     7261 acagaagtcc atctgacaga tcataagccg acgactggtg cgaataatcg tttcccttcc
     7321 ggagctgata tttctcgtgg tgatgtagat ggtacctatt tcatttgcaa agatggtttt
     7381 ccgtttgcaa ttcatgtaga tgctcgtttg gatgcttcta ttttgaattt agatcttaaa
     7441 aaggagaatc agcgcattga taaaacatat cctaaatttg cagaatgggc aaaaacgcgc
     7501 gatccgcaaa taaaatggtg gaaatagttg gagtgcatta gaataatcga ctatctttga
     7561 ggatgaaaaa ttaagaatag tactgatgta aaatattgtt tgttttgttt gtgttaaaaa
     7621 aagtgtggtt tcgggagaaa gtgtgctttg ttaaaaggag gattaagtat ttaatcctcc
     7681 tttttaatga ataacatcaa tcttttatag aaaggatgtt tggtaagggt ggaggcatct
     7741 cctaatataa caagcttcat tcgtgccctt gtaatcgcta cattcattct tcgcaaatca
     7801 ttcaggaatc caatctgtcc atcctcgttg gcacgtacaa gactgatgaa aataacgtct
     7861 cgctcctgtc cctgaaagcc gtctaccgta tttacggtga tgaggctgcg gaaagggcgt
     7921 aaaaagctgc ttccttttat ttttcctctc aaatattgca cttgtgcctt gtatggcgaa
     7981 atcagaccga aatcaattct ttcatccagt attcgctttt tgccgatacg ttcgatgtaa
     8041 gtttccagtt cttgcagtaa taggttagct tcctgcttat tgatgcgtcc gaaactttcg
     8101 cctacaaagt cttcgtgaaa gtccatctct gaagtatcga tccagttcat gggagtgtcg
     8161 aaatcaagaa tcccccgata gcgtacttcc ggagcagctt ccagttctcc atgataaaac
     8221 cagtcggagg gaaactgcat gatggcttca tgcattctgt actgtacttt tagtaaagaa
     8281 accgcagaag gtttttgctg aacgactttt tccattaatg tatgatccaa tcctccacgg
     8341 gaggcttcta tacatttgat agtcggcgga agttgacaat gatctcctgc aaggatgacc
     8401 cggtctgctt tgcggatagc gatccagcag gcagcttcga gggcttgtgc agcttcgtca
     8461 atgaataaag tcgaaaaacg acgtccgttg agcaggcggt ggttgctgct gactagggta
     8521 gaagcaatca cgcgggcact gtcgaaaaga tcggcattga tttgtatttc caactccgtg
     8581 gcgcggtcgc ggagacgact catgcgatta cgcattcctt cccgttcaga ataactaccc
     8641 cggcgcatcc ggctacccat ttcgcggata gatttacgga ttccccaaag ctccggatag
     8701 gcaggatgac tttcgaaccg gcgttcgtag gtggatgaaa gcattttgtc gttgactcgg
     8761 gttggatttc caatgcggag cacgggtact ccccggtcta ccagtttctc acaaatccag
     8821 tcgacagccg tgttgctttg cgcacaaaca agcacttgtg gttcccggtg caatgtttcg
     8881 taaatcgctt cgacaagagt cgttgtcttt ccggttcccg gaggaccgtg aacaatagat
     8941 acatcacgcg tacatagcac cttgttgact gctgtttcct gtgtactgtt cagccatggg
     9001 aagcggacag gatataattc gcggaatccc ggcttttggg tacccaacaa aatgtcgcgc
     9061 agttccgcca ggcggttgtc tttggcgcgt atcgtgtctt ccagtgcctc gaacatggcc
     9121 cggtacgatg tttcgtcaaa ataaagttgt actcccagta taccgtcagt ttgcagttcc
     9181 gctaaagctc ccgctccggg gagtacaacg accattcgtt cttcgtcggc aaagctgaca
     9241 gtagcgatga aattcatgta cttcactttt ccttcgaatg actggtggaa aaagcaaaca
     9301 ggacggccga actcaaagga atgctctatt tctttatttt cggtccgtgt aatatctatt
     9361 acaagctgat tcagcgaatt gtagtaactt cgaccaagag agacaggata ccagcagaga
     9421 ccgcgcttca ctttacgggc aacgcccatt gtttcggtct gccgcttaaa ttcttccttc
     9481 tcatattcat actccatccg caggaggagt tgctgttgct gaaggtctat aatgggactt
     9541 ttcggattat tactcataat aggcgcaaag gtaacaaatc ttcgttccgg gtagaaaaaa
     9601 tatttcattt tgttaaacat tactcgaacg tcgttcgtta ttttaataga tagactaaaa
     9661 aaacaaaaag caatatggta tatgatgtga ctatgttaga agctttctac gctgcttata
     9721 aaggaaaggt agaacacgta cgggctatac tgaaacgccc tttgacgttg gccgagaaaa
     9781 ttttgtatgc tcatctgtat gatgtagccg atttgaaaga ttacaaacgg ggggaggatt
     9841 atgtgaattt ccgtcccgac cgtgtggcta tgcaggatgc aactgcgcag atggctttgc
     9901 ttcaatttat gaatgcaggt aaggatcagg tggctgtgcc ttcgacagta cattgcgatc
     9961 atttgataca ggcgtataaa ggtgcaaagg cggatattgc tacggcaaga ctgactaatg
    10021 aagaagtata cgacttcctc cgtgatgtat cttcccgtta tggcatcggc ttctggaaac
    10081 cgggagcagg aattatccat caggtggtgc tcgaaaacta tgctttcccc ggcggtatga
    10141 tggtgggaac agactctcat acgcctaatg caggcggact gggcatggtg gctatcggtg
    10201 ttggtggtgc ggatgccgtg gatgtgatga caggaatgga atgggagctg aaaatgccga
    10261 agattatcgg tgtccgtctg accggaaaac taagcggttg gacctctccg aaagatgtaa
    10321 tcctgaaatt ggccggcatc cttaccgtaa aaggaggaac gaatgctatt atcgaatatt
    10381 ttggtcccgg aactgaatcc ctttctgcta ccgggaaagc taccatttgc aatatgggtg
    10441 ccgaagttgg agctactacc tctttgttcc cctttgacgg acgcatggct acttatttga
    10501 gagctaccgg aagagattgt gtagtcgatt gggctgaatc tgttggtgca gaccttcgtg
    10561 cagacgacat tgtgaccaac gaaccatcca actattacga ccgtgtaatt gaaatagact
    10621 tgtcagaact cgaaccttat ataaacgggc catttacacc ggatgccgct actcctatct
    10681 ctgaatttgc agaaaaagtg ttattgaacg gctatccccg taaaatggag gtgggcttga
    10741 taggttcatg taccaattct tcttatcagg atttgagccg tgcagcttct ttggcaaagc
    10801 aggtgacaga aaagaatttg agcgttgctt ctccgctgat cgtcaatccg ggttcggagc
    10861 aaatccgggc tactgccgaa agagacggta tgattgaggc ttttgaacgg ctgggagcca
    10921 cgattatggc aaatgcttgt ggaccttgta tcggtcagtg gaaacgtgag acggacgatc
    10981 cgacacggaa aaactcaatc gtcacctctt ttaaccgtaa ttttgccaaa cgtgctgacg
    11041 gtaatcccaa cacctatgcg tttgtagctt ctccggaact aacgatggcg ttaacgatag
    11101 ccggtgatct ctgtttcaac ccgttgaaag acagattggt gaatcataac ggagaaaaag
    11161 tgaaactctc cgagcctgta ggagatgaac ttcctttgaa aggttttgaa cagggaaatg
    11221 agggatatat tgccccccac ggagcaaaaa cggaaatcag ggtaaaaccg gattcccaac
    11281 gtctccagct tctgactcct ttcccggcat gggacggaca ggacttgctg aacatgcctt
    11341 tattgattaa agcacaggga aaatgtacta ccgaccatat ctctatggca ggtccgtggc
    11401 tccgcttccg tggacatttg gagaatattt ccgacaatat gctgatggga gctgtcaatg
    11461 ttttcaatgg tgaaacgaac cgtgtttgga atcgttcgac aaatacttat ggaacagttt
    11521 ccggtacggc aaagatgtat aagtccgaag gtattccgtc tattgttgtt gccgaagaga
    11581 attatggaga aggttccagc cgtgaacatg cagccatgga accacgcttc ctcaatgtac
    11641 gtgtcatttt ggctaagagt tttgcccgta tccacgaaac aaacctgaaa aaacaaggaa
    11701 tgcttgctct tacttttgta gataaagcag actatgataa aattcgggaa cacgatcttc
    11761 tgtccgtatc aggcttagtc catttcgcac cggggcgcaa tctgacgatt attcttcatc
    11821 acgaagacgg aacgaaagaa agttttgaag tgcaacatac ctataatgaa cagcagatag
    11881 cctggtttcg tgccggttct gccttaaatg caagataaaa aatgagcaaa ataaccatgc
    11941 aaacagatgg tacgttgttg gtacccgatg tgcctaccgt accttatatt accggcgatg
    12001 gagtaggagc cgaagtgact cctgccatgc aagccgtagt ggatgcagct atccggaaag
    12061 catatagtgg caaacgtcgg atcgaatgga aagaagtgtt ggcgggagaa cgttccttca
    12121 acgcgactgg ttcctggttg ccggatgaaa caatggaaac ttttcaggaa tacctggtag
    12181 gaatcaaagg tccgttgaca actcctgtcg gaggtggaat ccgttcgttg aacgtagcac
    12241 tgcgtcagac acttgattta tacgtctgtc ttcgtccggt tcgttggtat cagggagtac
    12301 agtcgcctgt caaatcaccg gagaaagtga acatgtgtgt gttccgtgaa aatacggaag
    12361 atatttatgc aggtatcgaa tgggaagccg gaactccgga agctgaaaag ttctatcaat
    12421 tcctgaaaga cgaaatgggc gtgacaaaag tccgtttccc ggaaacctct tctttcggtg
    12481 tgaaacctgt atcacgtgag ggcacggagc gtcttgtgcg tgctgcctgc cagtatgcgc
    12541 tcgaccatca tttgccttcc gtaacgctgg tgcataaagg gaatatcatg aagtttaccg
    12601 aaggtggttt caaaaaatgg ggctacgaac tggcgcaacg tgaatttggc gatgctttgg
    12661 cagatggcag actggtgata aaagattgca ttgcggatgc tttcttacaa aatacactcc
    12721 tgattcccga agaatattcc gtgatagcca ccttaaacct caacggagac tacgtttccg
    12781 accaactggc ggccatggta ggcggtatcg gcattgctcc gggagcaaat atcaactacc
    12841 agacaggtca tgccatcttt gaagcgactc acggaacagc tcccaatatt gcgggaaaag
    12901 atgtagtgaa cccttgttct ataatccttt cggcagtaat gatgctcgaa tattttgact
    12961 ggaaagaagc ggctgctctg atagagaaag ccttggaaca aagcttcctg gacgctcgtg
    13021 ctacacacga tttagcccgt tttatgccga atggaacctc cctctctact tccgctttca
    13081 ctcgtgagat cgtggaaaga attgaaaaac aaaagtaacg aataaaaaac gaagaaagat
    13141 gaaaaaagag tacttgattt acaagctttc cgaggaaatg aaggaagcta cccggattga
    13201 tacagaattg ttctccaagt ttgatgtgaa gcgcggattg cgtaatgaag acggcacagg
    13261 tgtattggta ggtttaacca gaatcggtaa tgtagtagga tatgaacgtg ttccgggtgg
    13321 tgggttgaaa cccataccgg gaaaactgtt ctatcgcggt tatgatgtag aagatatttc
    13381 tcacgctata atcaaagaga aacgctttgg cttcgaagaa gtggcttacc tattgctttc
    13441 cgggcgtctg ccggataaag aagaattgct ttctttccgt gagttgatta acgacaatat
    13501 gccgttggaa cagaaaacga aaatgaacat catcgagttg gaaggaaaca acatcatgaa
    13561 tattctttca cgcagcgtac tcgaaatgta tcgttttgac gcaaatgcgg atgatacctc
    13621 tcgggataac ttgatgcgtc agagtattga actgatttca aagttcccca ctatcattgc
    13681 ttatgcttat aatatgcttc gtcatgctac tttcggacgt tctctgcata tccgccatcc
    13741 gcaggaaaag ctctctattg ccgagaattt cctgtatatg ctgaaaaaag actataccga
    13801 actggatgca cgcaccctcg atttgttatt gattcttcag gcagagcacg gtggtggtaa
    13861 taactccact ttcaccgttc gcgtaacttc ttctaccgga acagatactt attcggccat
    13921 cgccgctggt atcggttcgc tgaaaggccc gcttcacgga ggtgccaata ttcaggttgc
    13981 cgacatgttc cagcacctga aggaaaatat caaagactgg acaagtgtag atgagataga
    14041 cacttactac acccgaatgt tgaacaaaga agtgtataac aagaccggac tgatctatgg
    14101 tatcggacat gccgtttata ccatctccga ccctcgtgct cttctattga aagaactggc
    14161 tcgcgacctt gcccgtgaaa aaggcagaga aagcgaattt gctttcctcg aactgctaga
    14221 agaacgtgcc atcgctactt tcggacgggt taaaaacaac ggaaagacag tgtccagcaa
    14281 tatcgacttc tattcgggct tcgtgtatga aatgatcggt ttgccgcagg aaatcttcac
    14341 tccactgttt gccatggcac gtatcgtagg ctggtgtgca caccgcaatg aagaattgac
    14401 tttcgacggt aaacggatta tccgcccggc ttataaaaat gtacttgatg atttggctta
    14461 tatcccaatt aagaaacgct gataagaaca aatcctttta ttgaatagat aagtaatccc
    14521 ggatgtgtgc ccgatcattt cagaagcgca tccgggaaat tttacatttt ctcctttttt
    14581 atgttcgtaa aagaatgtac ttcagattct ttctattttt tgtatcgtcg tttatctcat
    14641 ttttgttata tttgatgtag tctgaaggta tttaattgac tacaaataga ttaaaagaaa
    14701 ctcgcatgag aatgggcaac ggataagaaa ttggtaaagt gctttgatac actatatttc
    14761 tcatgctgtc aaacaactct tatttgtttg caaatataat attattgcag gtaataatca
    14821 aaaataacga ggtttatttt catttttacc tgctgatatt tgttccggat tatcagatgc
    14881 gatatatttg taattaggat tcgtaccgtg ttccaagcgg ttcataagta acgacttgcg
    14941 gagttttggc aacaagggga tgcggctccg ttttatagaa atgacttatg caaaccgact
    15001 tatccattta caacagtctt cgcccttcct ttatagaagg cgttcacgcc gtgaagttca
    15061 atgctttgtc ggcggtcata tcgcgttacc gggattatgc ccgcagttcc gaacaaataa
    15121 aagcgtactc gggagattct ctgctgatgc gggacatcgc ctccttgctt gacgaagcac
    15181 cccgtcccat aacgagggaa taccaggatt tcaccccgtt cctgcttctt ctgatgcttt
    15241 cggaggaatt tcatgtcgtc cattacgtcg agcgtcttgt aacgtggtat ttcggctact
    15301 gttgtgtcga tgaactgcgg acggtttgca ccattctgtc cgagtgttcc tacccgcatc
    15361 acgacacgct gcgg
//
