LOCUS       c00354_gnlPro..        10993 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BHKNFCMO_354.
ACCESSION   c00354_gnlPro..
VERSION     c00354_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 11:21:57
            Original ID  :: gnl|Prokka|BHKNFCMO_354
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10993
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10993
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[675:4887](-)"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(676..4887)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..10993
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10993
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(51..671)
                     /locus_tag="ctg354_1"
                     /transl_table=11
                     /translation="MATTEHSDLEQQIIKTAQQLFIEKGFVETSMSDIAATVGINRPTL
                     HYYFRTKDKMFKAVFGSIVMSLMPKIQDIVKQDIPFMERLSMILDEYIELFTSNPCLPR
                     FICGEIQRDVNHLLATAKELQFGDALSQVKDSILTAMEDGKLKKVPIHIVFLTVYSLLS
                     YPFLAKNLIVSLFLEDEAAFADFLQEWKQNIINQLQNLLCYEK"
     CDS             complement(676..4887)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg354_2"
                     /sec_met_domain="HGD-D (E-value: 1e-21, bitscore: 67.4,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 3.1e-34, bitscore:
                     108.0, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAYKVGLDIGSTTTKMVVLDKDGTTVLFSGYKRHQAKIQECLLG
                     FLYQIKEQLGDIPLSFHITGSVGMGISEKCSLPFVQEVVAATNYVRREHPHTATMIDIG
                     GEDAKVVFFQDGQATDLRMNGNCAGGTGAFIDQMAILLGVSIDELNELALRSNQVYSIA
                     SRCGVFCKTDIQNLMAKNISKENIAASIFHAVAVQTTVTLARGCNIVAPVLLCGGPLTF
                     IPALRKAFANYLNLSQDTDFILPEKGNLIPAWGAALAENNEESIHLSNLIQVIENKLSV
                     TSPFQSDLSPIFDSEEEYRSWKKEKDQYKIQYASLRPGLQEATIGIDSGSTTTKIVVLD
                     NNHRILYSYYHDNNGNPIKTVENGLQKLYEECRRRGTTLRIKGGCSTGYGEDLIKAAFH
                     MDAGIIETIAHYAAAKHISKEVSFILDIGGQDMKAIFVNDGVINRIEINEACSSGCGSF
                     ISTFAQSLDYSVEDFAKAACFSQAPCDLGTRCTVFMNSKVKQVLREGASVADIAAGLSY
                     SVVKNCLYKVLQLKDTEILGDHIVVQGGTMRNDSIVRSLEKLTGKQTFRSNCPELMGAL
                     GCALYAKQIENARVTELNEMLQWAQYTSKQLQCRGCENQCAIMRYTFNSENHYFSGNRC
                     EKVFSNKGSHADKGINTYDKKLELLFDRSADIPQPLFTIGIPRILNMYEEYPFWHTLFT
                     ACGIQVQLSEPSTFSKYETAAGMVMSDNICFPAKLVHSHIRNLTLQNVNRIFMPFVVFE
                     KKDKQQQNSYNCPIVSGYSEVIKSVQEENIPIDAPTITFKDEALLYKQCYEYLKSLGIR
                     DEVYKNAFSRALQEQYAFEEKIAAYNQEVLNEGREKHKLIILLAGRPYHSDPLIQHKVS
                     DMIAAMGVYVITDDIVRQQEISLEKTHYLSQWAFTNRILKATKWAAMQEGDIQYMQMIS
                     FGCGPDAFLIDEVRNLLKRYSKNLTLLKIDDVNNIGSIKLRVRSLVESLNFSLKHSQTK
                     DPEPFVSTAPFTKKDKKKKILAPFFTPFISPLIPSIMKVAGYEMETLPLSDTASCDWGL
                     KYSNNEVCYPATLIVGDIVKAFKSGRYDPANTCVAITQTGGQCRASNYISLIKKALIEN
                     GYTNTPVVSLAFGSGIENEQSGFKVNWLKVLPIILASVLYSDCIAKFYYAAVVREKERE
                     QAARLRDLYLDTAQPIIQKNKPEDLLSYLYLAARDFNKICEQRSCHKVGIVGEIFLKFN
                     PFAQKDVTSWLINQKIEVIPPLISDFFMQGFVNLKVRQNQHLQRKLTPDFVIDWLYKKV
                     QKQINKVNEIGKSFNYFIPFESIFEKAEKAKQVISLGTQFGEGWLISGEILSFASQGVN
                     HVISLQPFGCIANHIVEKGIEKRIKSLCPQMNILSLDFDSSVSDVNITNRLLLFIDNIN
                     N"
     CDS             complement(5512..5874)
                     /locus_tag="ctg354_3"
                     /transl_table=11
                     /translation="MSYITTFTGKHFDPIHPVPEKIDMKDIAHALSLICRANGHTRFFY
                     SVAQHSIACCKEAKTRGLSNHIQLGCLLHDSCETYMSNVTRPIKAKLTEYLKFEDHLQN
                     MIWNHFISEPLSDTEN"
     CDS             6050..6382
                     /locus_tag="ctg354_4"
                     /transl_table=11
                     /translation="MAERGDSLRISTTTNFSRRLDKFSSSRFYQMTYIGVPLIVGGLIV
                     KREDDHFRGLRNEYLPRFNRHLDDYMQYAPAAVMLGMKVAGVQSRSSWGRMLVSDAFSA
                     LLMGVW"
     CDS             6469..7230
                     /locus_tag="ctg354_5"
                     /transl_table=11
                     /translation="MTATMFTKEYGHKSPWVGVGAYSVATATGLMRMANNKHWLSDVLT
                     GAGIGILSTEVGYYFADLIFREKGINRFANENMFDRMDKPSFVSLYLGLNIPLSGYDID
                     EEMEFRTSSGSSAGVEGAYFFNPYVGVGGRFTVSNTLIIVNEERAENNTFDAISLCGGS
                     YFSYPLSSRWLIGSKLLGGYVHYPQLELTDRSVSSRSGFCMGSGVSLTFKAKEYYGIRF
                     FLDYNLLPSHSRNSGEYMNMLTLGSSFMITF"
     CDS             7406..7846
                     /locus_tag="ctg354_6"
                     /transl_table=11
                     /translation="MVIKTILSVLSLFVMLSCSMTGKKDIKQQPGMCAKLPMAADGIVR
                     LSKIEVYPEYLEEYMKYATEVGEVSLRTEPGVLTMYAVSEKENPGRITILETYASQEAY
                     KSHIASEHFQKYKQGTLHMVKTLVLSDQMPLNPANCINNFIQ"
     CDS             7858..8685
                     /locus_tag="ctg354_7"
                     /transl_table=11
                     /translation="MNKLLLFSVFSILTLNVMAQEKIVQTAGRDQLGTFAPKFAELNDD
                     VLFGEVWSRTDKLGLRDRSLVTITSLISMGITDNSLVYHLQSAKKNGITRTEIAEIITH
                     IGFYAGWPKAWAAFNLAKGVWSEDIVGEDAKTAFQREMIFPIGEPNTAYAQYFIGNSYL
                     ASVSREQVNISNVTFEPRCRNNWHIHRATKGGGQMLIGVAGRGWYQEEGKPAVEILPGT
                     VIHISANVKHWHGAAADSWFAHLAFEVSGENTSNEWLEPVTDDEYNKLEQTKR"
     CDS             8914..9477
                     /locus_tag="ctg354_8"
                     /transl_table=11
                     /translation="MKQIIFIFMSLLCFSCSSKAQNQTADTNVQSDKKILVAYFSCTGT
                     TEKAADAIAKTVGGKLYQITPATAYTSADLDWNNKSSRSSIEMTTENSRPELGGEALNL
                     KDYDVIFLGYPIWWNLCPRPVNTFLEKYDFSGKTVIPFATSGGSSITNSVKQLKKLYPK
                     IVWGESRLLNGSVKQAGEWAKGVI"
     CDS             9583..10161
                     /locus_tag="ctg354_9"
                     /transl_table=11
                     /translation="MLLEKLLKEFNFSTNIFNWEEFKLFDQYFERILVSKGTFLIKEGE
                     TERYSYFVFDGILRCWLLNHNGEEQTFWFCKEGTFSMSNISFTLQTRSAFNVQTIVDSV
                     IYRIDKKQVNELYTAIPKVKTVFEDLNAILLNKLLKRNIDLIKYSPEQYYLQMMEEYGI
                     TLNYIPLKDIASYLGITPQALSRIRKRIF"
     CDS             10226..10648
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_10"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg354_10"
                     /sec_met_domain="Acetyltransf_10 (E-value: 3.8e-19,
                     bitscore: 58.4, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRKIKVTDYPRLMEIWESAVLSTHDFLKEEDFLYYKERLPVYFQ
                     YVNLFGFEQEGILIGFMGIAEGNLEMLFIDNKYRGAGIGKKLITYAIDNLQVTKVDVNE
                     QNVQAVGFYEYMGFNIYKRSNLDGEGKEYPILHMQL"
ORIGIN
        1 aaacaaaaag agactgaata ttcagtctct ttttgtttat agtgtctata ctatttctca
       61 taacacaata agttctgcaa ttggttgatg atgttttgtt tccattcttg caggaagtca
      121 gcaaaagcgg cttcatcttc caagaataaa gatactatca ggttcttggc aagaaatgga
      181 tagctcaata ggctgtagac agtcagaaat acaatatgta tcggaacctt tttaagttta
      241 ccgtcttcca ttgctgtcag tatactgtct ttcacttggg ataaagcatc tccgaactga
      301 agttcttttg cagtggcaag caagtggttt acatcacgct gtatttctcc gcaaatgaat
      361 ctgggaagac agggattact tgtgaaaagc tcaatatact catccagaat catgcttagt
      421 cgctccataa atgggatatc ctgttttact atatcctgta ttttcggcat taaagacatg
      481 actatcgagc cgaacacggc tttgaacatc ttatctttgg ttctgaaata ataatgtaaa
      541 gtgggccggt tgattcctac cgttgcagca atatcactca tgctggtctc cacaaatcct
      601 ttttctataa aaagttgttg ggcagttttt attatttgct gctctaaatc gctatgttcc
      661 gttgtagcca taattttagt tgtttatgtt gtcaataaaa agtaataatc tgtttgttat
      721 gttcacatcg ctgacgctac tgtcaaagtc taaagatagt atattcattt gagggcacag
      781 cgattttata cgtttttcta ttcctttttc tacaatgtga ttggcaatgc atccgaaagg
      841 ttgcaagcta atgacatgat tgactccttg ggaagcaaag gatagtattt caccggatat
      901 cagccaaccc tctccaaact gggtgcccaa ggagatgact tgtttagctt tttctgcctt
      961 ttcaaagata gattcgaacg gtatgaagta attgaaactt ttgccgattt cattcacttt
     1021 attaatctgc ttctggactt tcttgtataa ccagtcgata acaaagtcgg gagtgagttt
     1081 tcgctgcaag tgttggttct gtctcacttt caggttgaca aatccctgca tgaagaaatc
     1141 acttatcagt ggcggaatca cttcgatctt ctggttgatg agccatgagg tgacgtcctt
     1201 ttgagcaaaa gggttgaact tcaggaatat ttccccaaca atacctactt tgtgacagga
     1261 tctctgttca cagattttgt tgaagtctct ggcagcgaga tataagtagc tcaacaagtc
     1321 ctccggttta tttttctgga tgatgggctg tgctgtatcc agataaagat cgcgcagacg
     1381 ggcggcctgt tcccgttctt tctcacgaac gacagctgca taatagaatt tggcaatgca
     1441 atcactgtat aacacagacg caagtatgat tggtaaaacc ttgagccagt ttaccttaaa
     1501 accggattgc tcattttcga taccactgcc gaaagcaagt gataccaccg gtgtattggt
     1561 gtatccattc tcaatcaatg ccttttttat cagtgaaata tagttgctgg cacgacattg
     1621 tccaccggtt tgcgtgatgg caacgcacgt attggcagga tcataacgtc cgcttttaaa
     1681 ggcttttact atgtcgccga caatcaatgt tgccggataa catacttcat tattggagta
     1741 tttcaatccc cagtcgcatg atgcggtgtc gctcaacggt aaagtctcca tttcatatcc
     1801 ggccactttc atgatggacg gaatgagtgg tgagatgaaa ggcgtaaaaa atggagcgag
     1861 gattttcttc tttttgtctt tcttggtgaa aggagcagtt gaaacaaatg gctcgggatc
     1921 tttcgtttga gaatgtttca aactgaaatt caagctttcc accaacgagc ggactcgtaa
     1981 tttgatggag ccgatattat taacatcgtc tatcttgagc aaagtaagat tcttgctgta
     2041 tcgcttcagt aagttacgta cttcatctat aaggaaagca tccggaccgc agccaaaaga
     2101 aatcatctgc atatattgta tgtcaccctc ttgcattgcc gcccacttgg ttgctttcag
     2161 aatacggttg gtaaatgccc attgagagag gtaatgagtc ttttccaatg aaatctcctg
     2221 ctggcggaca atatcatcag ttatcacata aactcccatc gcagcaatca tgtccgaaac
     2281 cttgtgctgt atcagtggat cgctatggta agggcgtccg gcgagtaaga taatcagttt
     2341 gtgtttttcc cgtccctcgt tcagaacttc ctgattatag gcagcaattt tttcttcgaa
     2401 agcatattgt tcctgtaatg cgcgtgagaa ggcatttttg tatacctcat ccctgatacc
     2461 caaagatttc agatattcat agcattgttt atacagcaat gcttcatctt tgaaggtgat
     2521 agtcggagca tctatcggta tattctcttc ctgtacactt ttgatgactt ccgaataacc
     2581 ggaaacgatg gggcaattat agctgttttg ctgttgctta tcctttttct cgaaaacaac
     2641 gaacggcata aatatccggt tgacgttttg cagtgtcagg ttacggatat gactgtgcac
     2701 aagtttggca gggaagcaga tgttatcaga catcaccatg ccggcagcag tctcgtattt
     2761 gctgaatgta gagggttccg acaactgtac ctgaatgcca caagcagtaa ataaggtatg
     2821 ccagaaaggg tattcctcat acatgttcag aatacgtgga atacctatgg tgaatagggg
     2881 ttgtggaata tctgcgctcc ggtcgaataa taattccagc tttttatcat acgtattgat
     2941 gcctttgtcc gcatggcttc ctttattgga aaacaccttc tcacaccggt tgccggagaa
     3001 gtaatggttt tcactgttga acgtatatcg cataatggcg cactggttct cgcacccccg
     3061 gcattgaagt tgcttggaag tatattgtgc ccattggagc atctcgttca gctccgtcac
     3121 ccgggcattt tcgatttgtt tggcatatag ggcacaacca agagcaccca tcaattcagg
     3181 acagttactg cggaaggttt gtttcccggt cagcttttcc agacttcgta cgatggaatc
     3241 attacgcatg gttcctccct gcacgacaat atggtcgcca agtatctccg tgtcttttaa
     3301 ttgcagaacc ttatacaggc agtttttaac aacggaataa gataatccgg cagctatatc
     3361 cgctacggac gctccttccc gaagtacctg ttttactttg gagttcatga agactgtgca
     3421 acgtgtaccc agatcacatg gtgcttgcga aaaacaagct gctttggcaa agtcctccac
     3481 actgtaatcc agcgattgcg caaatgtgct gataaaagaa ccgcaaccgg aggaacaggc
     3541 ttcattgatt tcgattctgt tgattactcc gtcgttcaca aagatggctt tcatatcctg
     3601 tcctccaata tccaggataa aagaaacttc tttgctgata tgtttggcag cagcataatg
     3661 agcgatggtt tcaatgattc ccgcatccat gtggaaagcc gcttttatca gatcttctcc
     3721 gtaaccggta gaacatcctc cttttatgcg cagggtagtt cctcgtctcc ggcattcttc
     3781 atatagtttc tgcaagccgt tctctactgt ttttataggg tttccgttgt tgtcgtgata
     3841 ataggagtaa aggatacgat gattgttgtc gagtactacg attttggtgg tagtagagcc
     3901 ggagtctatg ccgatagttg cttcctgtaa tccgggacgc agactggcat attgaatttt
     3961 atactggtct ttttcttttt tccatgaccg atattcttcc tcactgtcga atataggaga
     4021 aagatcactc tggaaaggtg aggtaacact tagtttgttt tctattacct gtatcaggtt
     4081 ggagagatga atactttctt cattgttctc tgccaatgct gctccccagg cagggatcag
     4141 atttcctttt tccggtaata tgaaatctgt atcttgtgac agattcagat agttggcaaa
     4201 tgctttccga agggccggaa taaaagtcaa tgggccaccg cagagtaata ccggagctac
     4261 gatattgcaa ccgcgtgcaa gtgtgacagt ggtctgtacg gctactgcat ggaaaatgga
     4321 agctgctata ttttctttag atatattttt ggccatcaga ttctgtatgt ccgttttgca
     4381 gaatactccg cagcgtgaag cgatagagta tacctgattg gaacgaagtg ctagttcatt
     4441 caattcgtcg atggagactc caagcagaat agccatctgg tcaatgaaag ccccggttcc
     4501 gccggcgcaa tttccattca tgcgcaggtc tgtagcctgt ccgtcctgaa agaaaacaac
     4561 tttcgcatct tctcctccaa tatcgatcat agtggctgtg tgcggatgct cccggcgcac
     4621 atagtttgtt gcagctacaa cctcttgcac aaacggcaga gagcatttct ctgaaattcc
     4681 cattccaaca gagcccgtaa tgtggaaaga taaaggaata tcacccaact gttcctttat
     4741 ttgataaaga aatccgagta aacattcttg tatttttgcc tgatgccttt tgtatccgga
     4801 aaacaagact gtagttccat ctttatccaa tactaccatc ttagtggtag tagagcctat
     4861 atctaaaccc actttatatg cattcatata ccaaacatct taaattagac ctcgtgtttg
     4921 acacctatgt cagacgcaaa tgtatgtaaa aatatggtag atacggcaaa tcgtaattga
     4981 agttttgggt ttaattaacg aattgggaaa aaagaaagat ggaatgtgag ggaggaaaac
     5041 gattgtgtaa ataaagaagt aaatgaatga ttgtatgctt atattacttg taaggttgta
     5101 gcagatcttt tatggtgaat cctagaaatc ttgtttactc tatttttgac aaaaggaaac
     5161 gtggctttta ataaacccgg attctgttta taataaactt tttgatagtt ttagtaaaac
     5221 ggtattcgag tttattataa actattgtag aacagtttta gaatcagacg agagatttta
     5281 agctgaatta taaacaaaat ggggcaataa tcattcgact attgccccat atcgtatagg
     5341 agtggtattg taaaatatca ggttatttat gatttatgta tgattatttc ttactatttt
     5401 catgttgctt atactttttc ttttctcaaa gatacaacat aaaaagtcct ttgtcaagag
     5461 tctgatgaga aaagtatctt atcggtttta aaaataaagt ccgcgtgcca tttagttttc
     5521 tgtatccgag aggggttcgc taataaaatg attccaaatc atattttgca ggtgatcttc
     5581 gaatttgaga tattctgtaa gtttggcttt tatcggacgt gtcacatttg acatataagt
     5641 ttcacagctg tcatgcaaca aacatcccaa ctgtatatgg ttggaaagtc ctcgtgtttt
     5701 agcctctttg cagcacgcga tagaatgttg ggcaacagaa taaaagaaac gggtatgacc
     5761 gtttgcacga cagatcaaag acaaggcatg agcgatgtct ttcatatcaa ttttttcagg
     5821 aacaggatgg atggggtcga aatgcttccc cgtaaaagtt gtaatgtaac tcataactat
     5881 agaatttata gtcatatttt tgtaaatctt caaactttct acaaagttgc ctgttatctt
     5941 tgtatcctaa ttcaaaagaa attacgatag catgaaaagg attgtaatat gcattgttgg
     6001 catttgtagc ttttctttct tatcggctca aaattcggca gataatgtaa tggcagaaag
     6061 aggggatagt ttgcgtatct ctacaacaac caattttagt agaaggcttg ataaattctc
     6121 atcttcccgt ttctatcaga tgacgtatat cggcgttccg ttaattgttg gtggcttgat
     6181 tgtaaaaagg gaggacgacc attttcgagg tttacgtaac gaatatctgc cccgtttcaa
     6241 tcgtcatttg gatgattata tgcaatatgc ccctgctgcg gtgatgcttg gtatgaaagt
     6301 agctggagta caaagtcgca gttcatgggg tagaatgctc gtttccgacg ctttttctgc
     6361 actgctgatg ggtgtgtggt aaatactttg aagcaaacga cgaatgtcga gcgtccggat
     6421 ggttcaaaca aacactcttt tccatccgga catacggcta cggcatttat gactgctacc
     6481 atgtttacta aggaatacgg acataaaagt ccgtgggtag gtgtcggagc atatagtgtg
     6541 gctactgcaa ccggtcttat gcggatggca aacaacaagc attggttaag tgatgtattg
     6601 acgggtgcag gaatcggaat attgtcaacg gaagtggggt attactttgc tgatctgata
     6661 ttcagggaaa aagggatcaa taggtttgcg aatgaaaata tgttcgacag gatggacaag
     6721 ccttcatttg tcagtttgta tctcgggttg aatattccgt tgagcggtta tgatatcgac
     6781 gaagaaatgg agttccgtac ttcatcaggc agttcggccg gtgtggaggg ggcctatttt
     6841 tttaatccgt atgtaggcgt tggaggacga ttcacagttt ccaatacttt gattattgtc
     6901 aatgaagaac gggcagagaa taacaccttt gatgcgatat cgctttgcgg aggaagctat
     6961 ttttcatatc cgttgtcttc acgatggctg ataggcagta aacttctggg tggatacgtg
     7021 cattatccac aattggaatt aactgaccgg tcggtttctt caagaagtgg tttctgcatg
     7081 ggaagtgggg tttccttgac gttcaaagca aaggaatatt atggaatccg tttttttctc
     7141 gattataact tgcttccgtc acatagcaga aacagtggtg agtatatgaa tatgcttact
     7201 ttggggtcat catttatgat tacgttctaa atcgtagtat atttaattct tttattggca
     7261 atataattca tttcattcga attatgtacg gttctttatt gcagaatcgg ggatttgggt
     7321 acaaaaatcc gtaattgata tacaattcca ttcgttttat cgcagtaaat ttgcaatcag
     7381 aagtttaaca atgaaaagat agaagatggt gataaaaaca attctaagtg ttttgtcttt
     7441 attcgttatg ttatcatgca gtatgacagg gaaaaaggat ataaaacagc agcctggtat
     7501 gtgcgccaaa ttacctatgg cggctgacgg tattgtgcgg ctatcaaaaa tcgaggttta
     7561 tccggagtat cttgaagaat atatgaaata tgcgaccgaa gtgggtgaag tctccttgcg
     7621 tactgaaccg ggagtgctga ctatgtatgc cgtcagcgaa aaagagaatc ctggcaggat
     7681 aactattctt gaaacttacg cgagtcagga ggcttataaa tctcatattg catcggagca
     7741 ttttcaaaag tacaagcaag gaacgctgca catggttaag actctcgtac tctctgacca
     7801 aatgccgctt aaccccgcaa attgcattaa taacttcatt caataaacga aatgattatg
     7861 aataaactcc ttttattttc agtatttagt attttaacac tcaatgttat ggcacaagaa
     7921 aagatagtac agacggcagg acgagaccag ttaggaacgt ttgcccctaa gtttgcggaa
     7981 cttaatgacg atgttctctt tggagaagtt tggagccgca ctgacaaact cggtctgcgt
     8041 gaccgcagtt tagtaaccat tacctccctt atcagtatgg gaatcacgga caattcgctc
     8101 gtttatcatc ttcagtcggc gaagaagaac ggcatcaccc gcacggagat cgcagagatt
     8161 atcactcata taggtttcta tgcaggttgg ccgaaagcgt gggcagcgtt caatttggca
     8221 aaaggagtat ggtctgaaga tattgttggt gaggatgcca aaacagcttt ccagcgtgag
     8281 atgattttcc ctattggcga acccaataca gcctatgcac agtattttat tggtaacagt
     8341 tatcttgctt cggtttcgcg cgagcaggtg aatatctcta acgttacttt tgaaccacgt
     8401 tgccgcaata actggcatat tcaccgtgca acgaaaggtg gcggacagat gcttatcggt
     8461 gtagccggtc gaggctggta tcaggaagaa ggtaaaccgg cggtagagat tttgcctggt
     8521 acggttatcc atatttctgc caatgtgaaa cactggcacg gagctgctgc cgacagttgg
     8581 tttgctcatc tggctttcga agtttccggc gaaaacactt ccaatgagtg gcttgagccg
     8641 gtcacagatg acgagtataa caaactcgaa cagactaaac gatgattttt gctaatcctg
     8701 ctttatcttt tgaaaggaaa taatatgact accgaggaat tttaaggaat atgtaaagac
     8761 gcgcaaagcg cttaatacag aagaaataca tcgtttgata gacgatatga gcaattatca
     8821 aagtaatgga agaatgaaaa cgcctgtggg gttactccat cgtgataatg tctaaactaa
     8881 ttaatgataa gaaatattta aaatcaaaat aaaatgaaac agattatatt catatttatg
     8941 agtctccttt gctttagctg ctcatcaaaa gcgcagaatc agacagcgga tactaatgta
     9001 cagtccgata agaaaatcct ggttgcctat ttctcttgta ctggaactac agaaaaagcc
     9061 gccgatgcca ttgcaaaaac ggttggcggc aaactttatc agataactcc cgctacagcc
     9121 tatacctcgg cagatctcga ctggaacaac aagagtagcc gtagttcaat tgaaatgacg
     9181 actgaaaatt cacgtccgga attgggggga gaagcgctta atctgaaaga ttacgacgtg
     9241 atattccttg gttacccgat atggtggaat ttatgtccgc gtccggtcaa tacattcctt
     9301 gagaaatatg atttctccgg taaaaccgtt attccatttg ctacttccgg aggaagctca
     9361 ataactaata gtgtaaaaca actcaagaaa ctttatccaa aaatcgtatg gggagaaagc
     9421 cgattgttga acggaagtgt caagcaggcc ggagagtggg cgaaaggagt aatataaaga
     9481 tggctactga aaatatattc actaaatatg agaagttaaa tagggcggaa gtaatagtga
     9541 atatattaaa tgagtaagta tattacgaat catatttaga ttatgctttt agaaaaacta
     9601 cttaaagaat ttaattttag tactaatatt tttaattggg aggagtttaa gttattcgac
     9661 caatattttg aacgaatatt agttagtaaa ggtacatttt tgattaagga aggagaaaca
     9721 gagaggtata gttatttcgt ttttgatgga atattacgtt gttggctttt aaatcataac
     9781 ggggaagaac aaactttctg gttttgtaaa gagggtacgt tttcaatgtc aaacatatct
     9841 tttacattac aaactaggtc tgcatttaat gtgcaaacaa ttgtagatag tgttatttac
     9901 cgaatagaca agaagcaagt aaatgaacta tataccgcta tccctaaagt aaaaactgta
     9961 tttgaagatt taaatgctat attgttgaat aaacttttga aaagaaatat cgacttgatt
    10021 aaatattctc ctgaacagta ttatctacag atgatggaag aatatggtat tacattaaac
    10081 tatataccat taaaagatat agcttcttat ttgggtatca caccgcaagc actaagcaga
    10141 atccgtaaac gtatttttta acttgggttc agtgttttga atgtataagt aacgaacttt
    10201 gcgactttaa attgcaatta caagtatgat tagaaaaatt aaagttacgg attatccacg
    10261 tttgatggaa atttgggaaa gtgcagtatt gagtacacat gattttctta aagaggaaga
    10321 ttttctatat tataaggaac gacttccggt atattttcag tatgttaatc tattcggatt
    10381 tgaacaagag ggaatcttaa tcggatttat gggaattgca gaaggaaatc ttgaaatgtt
    10441 atttattgac aataagtatc gaggcgcagg aatcggaaaa aaattaataa cttatgccat
    10501 agataattta caagtaacta aagttgatgt gaatgagcaa aatgttcaag ctgtcggttt
    10561 ttatgaatat atgggtttta acatatataa aaggtcgaat ttggacggag aaggtaagga
    10621 atatcctatt ttacacatgc agttgtagtc tctgttcaat tataaacaga tgcttagtat
    10681 aggtaccttt aattgaagat gtaatgttac atttgaataa aatgattggt taaaaaatca
    10741 ttgtagagtt tgaatgggca catctatcgc ctacttaaac tctgttttaa atgaagtgaa
    10801 gaaaaagaaa aaagctctga atttcttgaa tttcagagct ttgctttaat ttactatttg
    10861 ctttcgcggt gcgtacggga ctcgaacccg tgaccccatg cgtgacaggc atgtattcta
    10921 accaactgaa ctaacgcacc aaattttaat tggattaact catttatatt tctctctgct
    10981 tcttagtgaa aga
//
