LOCUS       c00385_gnlPro..        13064 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OIJHKPNE_385.
ACCESSION   c00385_gnlPro..
VERSION     c00385_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 08:23:13
            Original ID  :: gnl|Prokka|OIJHKPNE_385
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13064
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13064
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[93:3064]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      94..3064
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13064
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13064
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             94..2322
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg385_1"
                     /sec_met_domain="Gly_radical (E-value: 1.1e-46, bitscore:
                     148.1, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1171.4, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSSEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERENNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     KFEEVMDNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIEGEFPCFGNNNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATDEDRIENLVTMMDGYFTKGAHHLNVNVLN
                     RDMLYDAMEHPENYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             2336..3064
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.5;
                     E-value: 1.4e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg385_2"
                     /sec_met_domain="Radical_SAM (E-value: 3.3e-29, bitscore:
                     92.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGITFSGGEPTFQAKALVPLVRELKEKGIHVCLDSN
                     GGLWNEDVEELFRLTDLVLLDIKEFNPNRHQTLTGRSNEQTIRTAAWLEEQEKPFWLRY
                     VLVPGYSDFEEDIRALGEALGKYKMIQRVEILPYHTLGVHKYEAMGQEYKMKGVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(3057..3506)
                     /locus_tag="ctg385_3"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRVDCDFTAKDVDTAHRYRGFSCWGYHYYIRK
                     SGEIEPMRDEDTVGAHARGYNAISLGVCYEGGLDENGKAADTRTPRQKEALHRLVHELL
                     QRYPEAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVIGEFSIN"
     CDS             complement(3493..3660)
                     /locus_tag="ctg385_4"
                     /transl_table=11
                     /translation="MKEIVSRILDVIMYLIPFFGKRKRDRVVREVRYHTTCKEVCKVKT
                     TEREKEHEKD"
     CDS             complement(3720..4223)
                     /locus_tag="ctg385_5"
                     /transl_table=11
                     /translation="MAMTVSYSVVPRKNPAKKSEPAKYYAQAQASGELDFEELCEAITS
                     RSTCTETDVRAAISGILYEVKRALKAGRIARLGDLGSLQIGLNSEGAASVKEFSGSMIK
                     GAHLIFRPGKTLAELMKILSYQQVQTRAVAQAGAGDGGGEDPDKNPDSGGDGSGDEEAP
                     DPTV"
     CDS             4417..4647
                     /locus_tag="ctg385_6"
                     /transl_table=11
                     /translation="MNYKEDSFLIRTYTKAELAHLYNPHVCLKVALQILRRWIIYNLPL
                     LHELEQEGYRARNRLLSPKQVATIIHFLGEP"
     CDS             4734..6848
                     /locus_tag="ctg385_7"
                     /transl_table=11
                     /translation="MKHFTIFQGFYYAIAEMTEEEIVSTIGSFTYREKVEEIRRIFAEQ
                     GEKAANEKKKELPAIAFSASYRGRRTKVNLVKYLGHIVIDIDHLSKEELARILPIIKRC
                     NYTRIAFISPKGMGVKIIVRACHPDETLPETLQEIEDFHHAAYTRLVSFYTELCQIEID
                     TSGQDVARTCLFSYDPEIYFNPNADAFLVDQPQASYKVSNRKNLSGSKQQTPPDGPPTN
                     EDTALNAHSANASLVLTLTYYHNKSEKYIAGNRNNYLHHLSCTFNRYGIPQEEASAFIK
                     SQFTDFPADETASLINSAYAHTDEFNTCKLNGTQKRILRIEQYISEHYETRYNEVLHIM
                     EYRRRHPDTEKPEPFRILDEMMENSIWIEINELGYPCTVKTIENLIYSDFSQSYHPIRE
                     YFELLPEWDGTDYIRILADSVQTSHQEFWAECLERYLVAMCAAATQENIVNHTVLLLCS
                     EIQNIGKTTFINNLLPPELRAYLSTGLINSNNKDDLAKITQAMLINLDEFEGMSGRELN
                     AFKDLVTRKVISFRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHPYSIQF
                     ITINYAQLYAQIKYLLNKPGYQYWFTQADNERLEENNEAFIFHSPEEEMVLTHIRKPER
                     FEKVYYLTVSEIAELIRERTGYQYSIGSKIQLGKVMTKHHFESKKGNNGRRYAVFIIDI
                     EQVKSNRLYE"
     CDS             complement(6918..7223)
                     /locus_tag="ctg385_8"
                     /transl_table=11
                     /translation="MEAKTNEEFFNVSALIDERFGKEGTASRAEAEEKAYAFYTGQIIE
                     DARKKAKITQAELARRIGSDRSYISRVESGQTEPKVSTFYRIMNALGCKIEFSMIL"
     CDS             7394..7810
                     /locus_tag="ctg385_9"
                     /transl_table=11
                     /translation="MLFNYTTYSLVLYYFSSSSPTKVRGVREELKLFLFYFFISTFYIS
                     LKKIRMLEILSHSSHFLPFLSPKRRREIGKTQPSFFDFSPHFQITPPIEADFRKYLLSL
                     MCKRSKESDMDNLMRKLPIGIQTFEDIRRKNILL"
     CDS             complement(7926..8237)
                     /locus_tag="ctg385_10"
                     /transl_table=11
                     /translation="MSTKNNMLTDISAELDKEFGAPGTPEREKFDEEAYAFYTGQILLD
                     ARREAKVTQSELAKRINATKSYISRIESGAINPSVGTFYRIINALGLKIEIVKPIMGI"
     CDS             complement(8209..8550)
                     /locus_tag="ctg385_11"
                     /transl_table=11
                     /translation="MRRKVIAYGQYYKDFLATLTEKEIQKVKYVLSLLGTEDRLPIKFI
                     KVIRDGLYELRISYNGNIYRIFFIFDEGQIVVLFNGFHKKTQKTPSSEIDKALKIKEEY
                     YEYKKQHAD"
     CDS             complement(8643..8897)
                     /locus_tag="ctg385_12"
                     /transl_table=11
                     /translation="MTPTVIEYRGDPKRYVSVILGAIDRGRLTYNGDANCEQTFRSLSS
                     VIDVISPKNGKALSIETLVSYEKKERAGEFSDYSEGKFE"
     CDS             complement(8915..9049)
                     /locus_tag="ctg385_13"
                     /transl_table=11
                     /translation="MENSLSDELFCSLKNELREVDAQISVHSKKLLELIDQKKELSSN"
     CDS             complement(9190..11265)
                     /locus_tag="ctg385_14"
                     /transl_table=11
                     /translation="MKKLKNKIAFVLLFILVSAMSQAKGLDPRFQILPLPQNIEILKGQ
                     GIAGSELAYIVSKGESKIPVLGTLLDALPRIEKQGTGITLSLSEQNTPESPEGYTLEIT
                     SRGVTIQSRGQAGLFYGCQTLEQLMEDSRDLRIPIPCLRMTDYPEISYRAVHFDTKHHL
                     DRAEYYYRTIDKLARYKVNAIIWEVEDKLRYTRRPEVGAPNAISKQEMQAISRYAKERN
                     IEISPLVQGLGHAGFILKRHWELRENPYSDWEFCPSDPRTYELQFDLYRDAMEAMPDGK
                     YLHIGGDEITAIGIDERCKATGKTAFELQMIWLKKVCDFAVEHGRTPIFWDDMPLKYAD
                     LWWLLHRPLTDDEIRKNWNTSRLDEAIKMFPKNCIYMRWHYEDPTVLSHQMLLKWYHKN
                     GLNVMGATAAATGETPFMPRNNSRAQYIKDFCKLVSQNQLKGILATAWDDASAHWETVM
                     RGLIAQGEYSWHPDGRTVDEFIRAHARREFGLSGQQMEFLTEMEKAAFFFDQALVVSGT
                     RNPAWGVSETFRLLDLPDSEKPGEWKRKYQGRLDTVRIESARYEKICKGLKVAEQAALR
                     NRYTLDIYKQTNELFHYPVKLLEVLEVYDSTKNDEERLQALVRIGDVCNSFKSMRAEFE
                     KTYSQTRFMESPEGYIADQNHHHHLSALSNNSDWIFLYEMPMVEKVERWLKEQKDN"
     CDS             complement(11279..12994)
                     /locus_tag="ctg385_15"
                     /transl_table=11
                     /translation="MKKFLLSSIFLFSLAYGVIACTEGLPTDNWEEPVVPVDPAVTTLR
                     GSFESKFVRYSKGQQHEAQMEEAKIVTLWKDTLWQNDRTHKQIVLWSGDKKYDDLTYEV
                     SDLVSDANSISASNIRLRFPSYIKGDDQALDCGNYESRTTTLIADALSEVPVTTLTTQD
                     PVKIWVTINTPADAVPGIYTGTIQVKSANEVKQKFNLELLVVDHQLPAVADWSFHLDLW
                     QFPFQLTTLCRDNGENVVPFSDEYFAMMKPFYQLLADAGQKVITTYIKDGAFNSGQTMV
                     KWSKNSSDEWIFDYTDFDKYVGKMMEWGINKQISCFSLAGWKTSVGYKDASGTDRTLEL
                     TIGTEEYNTVWSAFLTSFKTHLKEKGWFDKTVLYMDEIKEDGMKSIIALIKENDANWKI
                     GLSGGNVDSGIENSLYDYSTILGYERQSDNAVSTFYTSCSQQYPNNYVTAQTNPAEMSW
                     MAWYALAKGFDGYLRWAYDYWTQSDPTSAQDGSNASGDFNMIYRSENTAAAVPISSIRL
                     ELLREGIQDFEKARILNNGQLDAAIRNFTSASGREAAKWVGIAEGTLKELSAND"
ORIGIN
        1 atagagcata tttatgctga ttatatgaaa aatgattgta actttgtgcg ctctaaagaa
       61 taggataact acaacctcta attttatcat tttatggaat taaacaagat ctttaaagac
      121 ggtctttgga gcagcgaaat caacgtcaga gatttcgtaa gtcataacat cactccgtat
      181 tacggagatg cttcattcct cgaaggacct acagaacgta ccaaagccgt atggaaccgc
      241 tgcctcgaag cgttggcaga agaaagagaa aacaacggtg tccgctcatt agataatgtt
      301 accgtatcaa ccatcacttc ccacaaggcc ggatatatcg acaaggaaaa cgaactgatc
      361 gtcggcctgc agacagacga acttctgaaa cgtgccatca agcctttcgg aggtatcaac
      421 gtagtcagca aagcctgtca cgaaaacggc gtggaagtgg acgaccgcgt aaaagatatt
      481 ttcactcact accgcaagac gcacaacgac ggagtattcg acgtatatac ggaagaaatc
      541 cgttccttcc gttcgctggg attccttacc ggacttcccg acaattatgc acgcggacgc
      601 atcatcggtg actaccgccg tatggctctt tacggcatcg accgtctgat cgaagcaaag
      661 aaggaagatt tgcacaacct caccggtccg atgacagagg cccgcatccg cctgcgcgaa
      721 gaagtggcag aacagatcaa ggcactgaaa gacatgaaag tgatgggcga atattacggt
      781 ctcgacctga gccgtcccgc ttacacggca caagaagccg tacagtgggt atatatggct
      841 taccttgccg ccgtcaaaga acaagacggt gccgctatgt cactgggtaa cgtttcttct
      901 ttcctcgata tctatctgga atatgaactg agcaaaggaa ccatcaccga atcattcgcg
      961 caagagctga tcgaccagtt tgtcatcaag ctgcgtatgg tccgccacct gcgtatgcaa
     1021 tcatacaacg acatctttgc aggcgacccg acctgggtaa ccgaatctct gggcggacgt
     1081 ctcaacgacg gacgtaccaa agtgacaaag acctccttcc gtttcctgca gacattgtac
     1141 aacctcggcc cttcaccgga accgaacctg accgtactct ggagcccgga acttccggaa
     1201 ggattcaaag aattctgtgc aaaggtttct atcgacactt cttctatcca gtacgaaaac
     1261 gacgacctga tgcgtgaagt acgtcagtcc gacgactacg gaatcgcctg ctgcgtatca
     1321 taccaggaaa taggcaagca gattcagttc ttcggtgccc gttgcaacct ggccaaagcc
     1381 ctgttgcttg ccatcaacgg cggacgttgc gagaataccg gtacagtcat ggtgaagaac
     1441 atccccgtac tgaccagtga cacgctgaag ttcgaagaag taatggacaa ctacaaaaaa
     1501 gtgctgaccg aaatcgcccg cgtatataac gaagcgatga acatcatcca ctatatgcac
     1561 gacaagtatt actacgagaa ggcccagatg gctcttgtag atacgaaccc gcgcatcaac
     1621 ctggcttacg gtgtagccgg actttccatc gccctcgatt cactgtctgc catcaaatat
     1681 gcgaaagtaa ctgcccgccg caacgatatc ggtctgacag aaggcttcga catcgaagga
     1741 gaattccctt gcttcggtaa caacaacgac aaggtagacc accttggcgt agacctggta
     1801 tacttcttca gcgaagaatt gaagaaattg cctgtttaca agaatgcccg tcctaccctc
     1861 tccttgctga ctatcacttc caatgtgatg tacggcaaaa agaccggtgc tactcccgac
     1921 ggacgtgcca aaggtgttgc cttcgctccg ggtgccaacc cgatgcacgg acgcgacaag
     1981 aatggtgcga tcgcttctct gagttctgta gcgaaacttc gttaccgtga ctcacaggac
     2041 ggtatcagca acaccttctc tatcgttccg aaatcactgg gtgctacgga cgaagaccgt
     2101 atcgagaacc tcgtgacgat gatggacggt tacttcacca aaggtgccca ccacctgaac
     2161 gtaaacgtac tgaaccgtga tatgctgtac gatgccatgg agcatccgga aaactatccg
     2221 cagctgacta tccgcgtttc cggctatgcc gtaaacttcg tgaagctgag ccgcgaacac
     2281 caactggaag ttatcagccg tagcttccac gaacgtatgt aatctattac tctatatgat
     2341 gataaacgta cattcatacg aaagtatggg aacattcgac gggccgggct tacggctcgt
     2401 cgtttttctt caaggatgca acttccgctg cctctattgc gccaatccgg atacgatagc
     2461 aggaaaggga ggcacgccta ccccaccgga agaaatcgtc cgcatggcaa tgagccagcg
     2521 ccccttcttc gggaaacgag ggggaatcac tttctccgga ggcgaaccga cgtttcaggc
     2581 gaaagcactc gtcccgctgg tccgcgaact gaaagaaaaa ggcatccatg tctgtctgga
     2641 cagcaacgga ggactttgga acgaagacgt agaagaatta ttcagactga ccgatcttgt
     2701 gttattggat ataaaggaat tcaaccctaa ccgccatcag acgctcaccg gaagaagcaa
     2761 cgagcaaacc atccgcacgg ccgcctggct ggaagaacag gagaaacctt tctggctacg
     2821 ctacgtgcta gtgcccggat acagcgattt tgaagaagac atacgcgcac tgggagaagc
     2881 actcggaaaa tacaagatga tccaacgggt ggaaatactg ccttaccata cactgggcgt
     2941 acataagtac gaagcgatgg gacaggaata caagatgaaa ggggtaaaag aaaatacccc
     3001 cgaacagctt gaaaaagctg cggaggtatt caaagagtat ttcactacgg tggtagttaa
     3061 ttaatggaga attctccaat gacctcaaag caaggacatt ctttaatccg ttcccaagga
     3121 tctacgatcc cattatagtt ggtgtcggga cttaaatccc gatgccctac tactttagct
     3181 tccggataac gctgcaacaa ttcgtgtacc aagcgatgta gtgcctcctt ctgacggggt
     3241 gtacgcgtat ccgcagcttt tccattctca tccagaccgc cctcataaca tacacctaag
     3301 ctgatcgcat tatagccacg tgcatgagct ccgaccgtat cttcatcccg catcggctca
     3361 atctcgcccg acttgcgtat ataataatga tacccccagc acgaaaagcc acgataacgg
     3421 tgagccgtat ccacatcctt tgccgtaaag tcgcaatcga cacgggtggc ggaacaatgg
     3481 atcacaatca gactaatctt tctcatgttc cttttccctt tccgtcgttt tcactttgca
     3541 cacctcctta caagtagtat gatagcgcac ttctctcacc accctgtccc gttttctctt
     3601 tccgaagaaa ggaatcagat acatgatcac atctaaaatc cgacttacta tttctttcat
     3661 cttatcaaaa tattaatgga agttattcta attcgttatt accttgaccc gtctgccaat
     3721 tataccgtag ggtccggagc ctcttcatca ccggagccat caccaccgga atccggattc
     3781 ttgtcagggt cttctccccc gccatcgcct gcacccgcct gcgccaccgc acgagtctgc
     3841 acttgctgat aactcagaat cttcatcaac tccgccagcg tcttaccggg gcggaaaata
     3901 agatgcgccc ccttaatcat tgaaccggaa aattccttga ccgatgccgc accttcacta
     3961 ttcagtccta tctgcaaact gcccaaatcg cccagtctcg caattcttcc tgccttcaac
     4021 gcacgtttca cttcgtaaag aatacccgaa atagccgcac gtacatccgt ttccgtacaa
     4081 gtagaacgac tggtgatcgc ttcgcacaac tcttcaaagt ccagctcacc cgacgcctgc
     4141 gcctgtgcat aatactttgc cggttcgctc ttttttgcag gattcttgcg cggcaccact
     4201 gaataagata ctgtcattgc cataataaaa taattttaaa gtttataata cataggatgc
     4261 atccccttct tgttaacagc acaaagataa ggatagccgg acaagccata ttccccaacg
     4321 aagtttcttg attcccaacg aataaaaacg aagtcaaacc tttgaaaaac aaggaatttt
     4381 atgtaacttt atagcataaa acaagaagaa aacatcatga attacaaaga agattctttc
     4441 cttatccgca cctataccaa agcggaactg gctcaccttt acaatcccca tgtctgcctc
     4501 aaagttgctt tacaaatact tcgtcgttgg attatttaca acctccctct cctgcacgaa
     4561 ctcgaacagg aaggctaccg cgcacgcaac cgtctccttt cgccgaaaca agtggcaact
     4621 atcatacact ttttgggcga accgtagtaa cttattgcca ttttatacaa agttccttta
     4681 cacatttccg caaagaagtt cctttgcatc gacaaacaat aatcaaaata aaaatgaaac
     4741 atttcaccat atttcaaggt ttctactacg caatagcaga gatgaccgaa gaagaaatag
     4801 tgtccactat cggcagtttt acctaccggg aaaaagtcga agaaatacgc cgcatctttg
     4861 cagagcaagg agaaaaggct gccaatgaga agaaaaaaga attgccggca atcgccttct
     4921 ccgccagcta ccgaggaagg cgtaccaaag tgaacctcgt caaatatctg ggacacatcg
     4981 tgatagacat cgaccacctc agcaaagaag aattggcacg catcctccct attatcaaga
     5041 gatgcaatta cacccgcatc gcctttatca gtcccaaagg gatgggcgtg aaaatcatag
     5101 tacgcgcatg ccatccggat gagacattgc ccgaaaccct tcaggaaata gaagacttcc
     5161 atcatgcagc ttacaccaga ctcgtttctt tttacaccga actctgtcag atagaaatcg
     5221 acacctccgg ccaggatgtg gcacgcactt gtctgttctc ttacgatccg gagatttatt
     5281 tcaatccgaa cgctgacgct tttcttgtag atcaacctca ggcatcctac aaggtttcaa
     5341 atcgtaaaaa tctctccggc agtaaacaac agactcctcc ggacggcccc ccgacgaatg
     5401 aagacacagc gctcaacgcc cattccgcca acgcttctct ggtgctgact ttaacctact
     5461 atcacaacaa gtccgaaaaa tacatagcgg gcaaccggaa caattatctg caccatctct
     5521 catgtacctt caatcgctac ggcattccgc aggaggaagc atccgccttt atcaaaagcc
     5581 agtttacaga ctttccggcg gacgagacag cctctttgat caatagcgcc tacgctcata
     5641 ccgacgaatt taatacctgt aaactgaatg gcacgcagaa acgaatatta cggatagagc
     5701 aatatatcag cgagcactac gaaacacgct acaacgaagt gctgcatatc atggaatatc
     5761 gcagaaggca tcccgacacc gagaaaccgg agcctttccg catcttggat gagatgatgg
     5821 aaaacagtat ctggatagaa atcaacgaac tgggatatcc ctgcactgtc aaaacaatcg
     5881 aaaatctgat ttactccgat ttcagccagt cgtatcatcc cattcgcgag tactttgaat
     5941 tactgcccga atgggacgga accgactata tccgtatcct ggcggatagt gtccagacga
     6001 gtcatcagga gttttgggcg gaatgcctgg aacgttatct ggtggcgatg tgcgcagcgg
     6061 ctactcagga gaatattgtc aatcacacgg tacttctgct atgcagcgag atacagaaca
     6121 taggaaagac tacctttatc aataatctcc tgcctcccga actgcgtgct tatctctcta
     6181 ccggactaat caattcgaac aataaagatg atttagccaa aataacgcag gccatgctga
     6241 tcaatctcga cgagtttgaa gggatgagcg gccgggaact gaatgcattc aaagatttgg
     6301 taacgcgcaa agtgatcagt ttccgtctgc cttatgcacg ccgttcgcaa aacttccctc
     6361 atacggcctc ttttgcagga acctgcaatt atcaggaagt gcttcacgac acgacaggca
     6421 accggcgttt cctttgtttt catccttatt ccatccaatt tattaccatc aattatgcgc
     6481 agctctatgc tcagatcaaa tatctgctga ataagccggg atatcaatac tggttcacgc
     6541 aagcggacaa tgaacggctt gaagagaata acgaggcttt catctttcat tcaccggaag
     6601 aagaaatggt tcttacgcat atccgcaagc cggaacgttt cgagaaggtt tattatctga
     6661 ctgtcagtga gattgcggaa ctaatacgtg agcgtaccgg ttatcagtat tccatcggat
     6721 caaaaataca gttggggaag gtgatgacta agcaccattt tgaatctaaa aaaggaaata
     6781 acgggcgccg atatgccgta tttattatag atatcgagca ggtaaaatca aacaggctgt
     6841 atgaatagaa gcgggaaagc cttgtgaata tagcaaaatg cagagtcatc ttgacagata
     6901 ctctgcattt attgttttta caaaatcatt gaaaattcga ttttacagcc taacgcattc
     6961 attatacgat agaaagtaga tactttaggc tctgtctgac cactttctac tcttgaaata
     7021 taagaacggt cagaaccgat acgccgggct aattcagcct gagtgatttt agcctttttt
     7081 cttgcgtcct cgataatctg tcctgtataa aaggcgtagg ccttttcttc tgcctctgca
     7141 cgagaagctg ttccttcctt accaaaacgc tcatctatta atgcactgac attaaagaat
     7201 tcctcatttg tttttgcttc cataatactc ctttcttaat atctttgctt tatcaatttc
     7261 tttctttggt gttatttcgg ttttcagcac atacaatatc ttatcttggg tgccagcatc
     7321 taaattttca aagaattctt tgaagtatcc tttatatgct attatttctc ttttcataac
     7381 gcaaatataa gaaatgttgt tcaactatac aacatattcc ctcgttttat attatttttc
     7441 atcatcttca cccacaaaag tgagaggagt gagagaggaa ttgaaacttt ttctatttta
     7501 tttctttatt tctactttct atatttctct aaaaaaaata cgaatgttag aaatcctctc
     7561 tcactcctct cactttttac cttttctttc tccaaaaaga cggcgggaaa tcggaaaaac
     7621 acaaccgtct tttttcgatt tctcaccgca ttttcaaatc accccaccaa ttgaagcaga
     7681 cttcaggaaa tatttgttat ctttgatgtg caaaagatca aaagaatcag atatggacaa
     7741 cttgatgcgt aaacttccta ttggaataca aacctttgaa gatatacgaa ggaagaatat
     7801 cttattgtaa agatcggaat ggaatttagt gcagaaagcc ggaacttaaa tcgttggtta
     7861 atcgaagtga taggaaagta aaatatgaaa aaccgaagga tatcttaatc cttcggtttt
     7921 ttcgactata tacccatgat tggttttacg atttcaatct tcaatcctaa tgcattaata
     7981 attcggtaga atgttcctac acttggattt atagctccgc tttcaatacg tgagatatac
     8041 gatttagttg cattgattct ctttgctaat tcagactgag ttacttttgc ttcccgtcgt
     8101 gcatccaaca gtatttgacc agtataaaaa gcgtatgcct cttcatcgaa cttttcacgt
     8161 tccggagtcc caggtgctcc gaactcctta tcaagttctg cgctgatatc agtcagcatg
     8221 ttgttttttg tactcataat attcctcctt tatttttaat gccttatcta tttctgatga
     8281 tggggttttc tgtgttttct tatggaagcc attaaataaa acaactattt gcccttcatc
     8341 aaaaatgaaa aagatacggt aaatgtttcc gttatatgat atacgtagtt catatagacc
     8401 atcacgtata acctttataa atttgatagg caaacggtct tctgttccaa gcaatgaaag
     8461 cacatatttc actttttgaa tttccttttc cgtcagagtg gcaagaaaat ccttgtagta
     8521 ttgaccgtat gctattactt ttcttctcat tgtgcaaata taataaaagt ttcaatatca
     8581 tacaactttt aaagtcgaat ttatactgct aacgggctta aattccctct caggtactca
     8641 ttttattcga atttcccttc cgaataatct gaaaactccc cggcacgttc tttcttctca
     8701 tacgagacca acgtttcgat actaagcgct ttcccgttct tagggcttat gacatctatc
     8761 acacttgaca aggaccggaa cgtctgttcg caattcgcgt ctccattata cgtcaacctc
     8821 ccccggtcaa tggcacctag aataacagaa acataccgtt tcggatctcc ccgatattcg
     8881 ataacagtag gcgtcatttg ttcttcttcc cgaatcagtt ggacgacaat tctttttttt
     8941 ggtcaatcag ctccaacagt tttttactat gcacactgat ttgtgcatct acttcacgaa
     9001 gttcattctt caatgaacaa aacaattcat cactcaatga attttccata aaaacgattt
     9061 ttattaatta taaaaaagcc attccggaaa gcacagctat tgcctgcttc ccgaaatggt
     9121 gactaatacc ttcaaaaaca ctacgctgta ttgtcctcaa cagaacaata cgatatttaa
     9181 aatctaaggt tagttatctt tttgttcttt caaccatctt tccacttttt ctaccatcgg
     9241 catttcatac agaaatatcc agtcactgtt gttacttaaa gcagacaagt gatgatggtg
     9301 gttctggtcg gcaatatacc cctccggact ctccataaaa cgagtttgcg aataagtctt
     9361 ttcaaattca gcacgcatac ttttgaagga gttacaaacg tcacctatcc ttactaatgc
     9421 ttgaagacgt tcttcatcgt tttttgtact gtcataaacc tctaaaactt ccaacaattt
     9481 caccggatag tgaaacagtt cgttcgtctg cttataaata tccaacgtgt agcgattgcg
     9541 taaagctgcc tgttcagcta ctttcaagcc tttacaaatc ttctcataac gcgccgattc
     9601 aatacggacg gtatccagtc ttccctgata tttccgcttc cattctcccg gtttctccga
     9661 atccggcaaa tccagcaacc ggaatgtttc cgatactccc caagcaggat ttcgcgtgcc
     9721 ggaaacgact aatgcctgat caaagaagaa agcagctttc tccatttccg tcagaaactc
     9781 catttgctga ccggacaatc cgaactccct ccgggcgtgc gcccggataa actcatccac
     9841 agtccgcccg tccggatgcc aactatattc gccctgtgct ataagtccgc gcatcaccgt
     9901 ttcccaatgg gcagaggcat catcccaagc cgtggcaagg atgcccttca actgattttg
     9961 agaaacaagt ttgcagaaat ctttaatata ttgtgccctg gagttgtttc tgggcataaa
    10021 cggggtttca ccggtcgctg ctgcggtagc tcccattaca ttcagtccat tcttatgata
    10081 ccatttcagg agcatctgat gggacaagac ggtagggtct tcgtaatgcc aacgcatata
    10141 gatgcaattc ttcgggaaca tcttgatagc ttcgtccagc cgggaggtat tccagttctt
    10201 acgaatttca tcatcggtga gcgggcgatg caacaaccac caaaggtcgg catacttcaa
    10261 aggcatatca tcccagaaga tgggagttct gccatgttcc acagcaaagt cgcaaacctt
    10321 tttgagccag atcatctgca attcaaaagc tgtttttccg gtcgctttac aacgttcgtc
    10381 tatgccgata gccgttattt catctccacc gatatgaaga tacttgccat caggcatggc
    10441 ttccatcgca tcccggtaaa gatcaaactg taactcatag gtacgcgggt cggaaggaca
    10501 gaactcccag tcactatacg gattttcccg cagttcccaa tggcgtttca ggataaagcc
    10561 ggcgtgtccc aatccttgta ctaagggact gatttcaata ttacgttctt tggcatagcg
    10621 actgatagcc tgcatctctt gtttgctgat ggcgttgggg gcgcccactt cgggacggcg
    10681 ggtatagcgc agcttgtctt ccacttccca aatgatggca ttcaccttat agcgggccag
    10741 tttatcaatg gtccgatagt agtattccgc ccggtccaga tgatgcttcg tatcaaagtg
    10801 aacggcacgg taagagattt cgggataatc cgtcattcgg agacatggaa tagggatacg
    10861 aaggtcacga ctatcctcca tcagttgttc caaggtctga caaccgtaga acaatcctgc
    10921 ttgtccgcgc gattggatcg ttactccccg ggaggtgatc tccagcgtat atccttccgg
    10981 agattcgggt gtgttctgtt ccgacaggga aagtgtaata cctgttcctt gtttttcaat
    11041 gcggggtaag gcgtccagca atgttcctaa aacggggatt ttactttcgc ctttcgatac
    11101 gatatatgcc agttcactac ctgctatccc ctgccctttc aatatctcta tgttctgggg
    11161 taaagggagt atctgaaaac gtgggtccaa tccctttgcc tgcgacatcg cggagacaag
    11221 tataaacagc agtacgaaag ctattttatt ctttaatttc ttcattatct atttctgttt
    11281 aatcatttgc agatagttct ttcaatgttc cttcggctat tcctacccac ttggcggctt
    11341 cacgccccga agcagaggtg aaattgcgga tagctgcgtc cagttgtccg ttgttcagta
    11401 tacgtgcctt ctcaaaatcc tgaatgcctt cccgcagcag ttccagacgg atgctggaga
    11461 tgggaacagc ggcggcggta ttttcgctgc gataaatcat attgaaatcg ccggacgcat
    11521 tacttccatc ctgtgcactg gtagggtcag actgtgtcca gtaatcgtat gcccagcgca
    11581 gatatccgtc aaatcctttt gccagcgcat accacgccat ccacgacatt tctgccggat
    11641 tggtttgcgc cgtaacgtag ttgttcgggt attgctgcga gcaactggtg tagaaggtag
    11701 aaacggcatt gtccgactgg cgctcgtagc ctaaaatggt cgaataatca tacaggctgt
    11761 tctctatccc gctatcgaca tttcctcccg acagtcctat tttccagttc gcatcgttct
    11821 ctttgattaa agctatgatt gacttcatac cgtcttcttt aatctcatcc atataaagca
    11881 cggttttgtc aaaccagcct ttttctttca gatgtgtctt gaaagaagtc aggaaagcag
    11941 accacactgt gttgtattct tccgtaccga tggtgagttc caatgtccgg tccgtgcccg
    12001 acgcgtcttt atatccgaca gacgtcttcc atccggccaa agaaaaacag ctgatctgtt
    12061 tattgattcc ccattccatc attttcccga catatttatc aaaatcggta tagtcgaata
    12121 tccactcgtc ggaactgttt ttcgaccact tcaccatcgt ttgtccgcta ttgaaagcac
    12181 cgtccttgat atacgtggtg attaccttct gcccggcatc tgccaacagt tgataaaacg
    12241 gcttcatcat cgcaaaatat tcgtcggaga aaggaacgac attttctccg ttgtcccgac
    12301 acagagttgt caattggaaa gggaactgcc ataaatcaag atggaaactc caatcggcta
    12361 ccgcaggcaa ctgatgatct acgacaagca attccagatt aaacttctgc ttcacttcat
    12421 tggctgattt cacctgaatg gttccggtat atatgcccgg tacggcatct gccggcgtgt
    12481 ttatggtcac ccatatctta acgggatctt gagtggtgag cgttgtgacg ggtacttcgg
    12541 aaagagcatc ggcaatcaag gtagtggtgc ggctctcata atttccacaa tcgagtgcct
    12601 gatcgtctcc ctttatataa gaagggaaac gaagtcggat attggaggca gagatgctgt
    12661 tcgcgtcgct caccagatcc gaaacttcat aagtgaggtc gtcatatttt ttatctcctg
    12721 accataacac tatctgtttg tgtgtacggt cgttctgcca aagggtgtct ttccaaaggg
    12781 tgacgatctt cgcttcttcc atctgagctt cgtgttgctg acctttggag tatctcacaa
    12841 acttactttc gaacgaaccc cgcagggtag taacggcagg atctacggga acgacaggtt
    12901 cttcccagtt gtcggttggc aacccctcgg tacaggctat tactccataa gccagtgaaa
    12961 acaaaaatat actgcttaat aagaatttct tcataattgt tgatttatct cgttataata
    13021 taatcataaa aaggtgtact caagtctaat tctatccggt acgt
//
