LOCUS       c00491_gnlPro..        13507 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GKKKACFH_491.
ACCESSION   c00491_gnlPro..
VERSION     c00491_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 07:43:56
            Original ID  :: gnl|Prokka|GKKKACFH_491
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13507
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..3507
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg491_1"
                     /sec_met_domain="PFOR_II (E-value: 5.3e-19, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.5e-83, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 8.3e-32, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.5e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.7e-12, bitscore: 37.3,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.9e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.7e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.3e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="HISYMFSEVAAIYPITPSSTMAEYVDEWAAAGRKNIFGETVLVQE
                     MQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAGEFLPCVFHVSARTLASH
                     ALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATIKSRVPFMNFFDGFRTSH
                     EIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAENPDHFFQHRESCNNYYE
                     AVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSVTEAAREAIDHLVANGEK
                     VGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGEPLYLDVKDCFYGAENAP
                     VIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDDVTFTSLPQKEEIALGGE
                     GMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDSKKSGGFTCSHLRFGDTP
                     IRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIWEGEELAKNLPNKVKKYF
                     AQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPVDQAVEQMKKFIVKSYGK
                     KGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDPAFINEVVRPINAQDGDL
                     LPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCNKCAYVCPHASIRPFVLD
                     AEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADICPGNPKKGGKALTMKHL
                     ESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEFSGACSGCGETPYVKLIS
                     QLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANSLFEDFCEFGLGMELANE
                     KMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKELAEKIIPMVEAAKDKCN
                     HCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGKDVNILVLDTEVYSNTGG
                     QSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIAMGADQAQTLKAIREAEA
                     YPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWRYNPALEEEGKNPFQLDS
                     KEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKWRYNSYKRLARENWGADT
                     AE"
     protocluster    1..13507
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:3507](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1..3507
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..13507
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13507
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             3632..3820
                     /locus_tag="ctg491_2"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(3831..4691)
                     /locus_tag="ctg491_3"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(4719..5549)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg491_4"
                     /sec_met_domain="BPD_transp_1 (E-value: 3.1e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             complement(5546..6772)
                     /locus_tag="ctg491_5"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             7245..8531
                     /locus_tag="ctg491_6"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFMRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFVAIFTLPQPFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVAMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSTGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPVPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             complement(8494..8826)
                     /locus_tag="ctg491_7"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSAGRMVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(8854..11586)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 63.6; E-value: 6.4e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg491_8"
                     /sec_met_domain="Peripla_BP_1 (E-value: 1.2e-20, bitscore:
                     63.6, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFCLIGMTACRQDTPRFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKIAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDQLIQLSHQLEEATHA
                     KLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLRLVNQILD
                     FRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDNMPDTDYHTLADMEKL
                     ERIYFNLLSNAFKFTPENGRIAVRLSSLSKEDKRWIRFTVANTGSMISAEHIRNVFDRF
                     YKIDMHHTGSGIGLALVKAFVEMHGGTISVESDEKQGTVFTVELPVQSCEAVAAEPDTT
                     LVSADSRTTDVLLAEEEELEKGYDSSKSSVLIIDDNEDIRSYVHTLLHTDYMVIEAADG
                     SEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSLDEQRIQG
                     YDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDKDFVERFK
                     SLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKAASLLASS
                     DMTVAEIGYEVGFSSPSYFTKCYKEQFGESPTDFLKRKG"
     CDS             complement(11919..13145)
                     /locus_tag="ctg491_9"
                     /transl_table=11
                     /translation="MLFFLIVPLFLSLFYKPIAYLCGRSLNNKLKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYDSDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGLQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLMVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGRRVGRWKRYTIDG
                     KLEKEWDEN"
ORIGIN
        1 catatctcgt atatgttctc tgaagtagca gctatctacc ccatcactcc ttcttcgact
       61 atggctgagt acgtagacga atgggctgcc gcaggacgta agaacatctt cggcgaaaca
      121 gtattggtac aggaaatgca atctgaaggt ggtgctgccg gtgcagttca cggttctctt
      181 caggctggtg cattgactac tacttacact gcttctcagg gtcttctttt gatgatccct
      241 aacatgtaca agattgccgg tgaattcttg ccttgtgtat tccacgtttc tgctcgtaca
      301 ctggcttctc acgcattgtg tatcttcggt gaccatcagg acgtaatgtc agctcgtcaa
      361 accggcttcg ctatgttggc agaaggttct gtacaggaag ttatggattt ggcaggtgtt
      421 gctcatctgg ctactatcaa atcacgcgtt ccgttcatga acttcttcga tggtttccgt
      481 acttctcacg aaatccagaa gatcgaaatg ttggaaaacg acgacctcgc tccgctgatc
      541 gaccaggaag ctttggctga attccgtgcc cgtgcactga atccgatgaa gccggttgcc
      601 cgtggtatgg ctgaaaaccc cgaccacttc ttccaacatc gtgaatcatg caataactac
      661 tatgaagcag ttcctgctat cgtagaagaa tacatgaacg aaatttccaa gatcacaggc
      721 cgcaaatacg gtttgttcga ttactacggt gcagaagatg cagaacgcgt aattatcgca
      781 atgggttctg taactgaagc tgcccgcgaa gctatcgacc acttggtagc aaacggcgaa
      841 aaagtaggta tggttgccgt acacttgtat cgtccgttct ctgctaaaca cttcctggct
      901 gctgtaccca agactgcaaa gagcatcgca gtgcttgacc gtacaaaaga accgggtgct
      961 aacggcgaac ctctttacct tgacgttaaa gactgcttct atggcgcaga aaatgctcct
     1021 gttatcgttg gcggtcgcta cggtctgggt tcaaaagata caactccggc acagatcatc
     1081 tctgtattcg aaaacttggc tatgccaatg ccgaagaacc acttcactat cggtatcgta
     1141 gacgacgtta cgttcacttc tcttcctcag aaagaagaaa tcgctctggg cggtgaaggt
     1201 atgttcgaag ctaaattcta cggtctgggt gctgacggta ctgtaggtgc caacaagaac
     1261 tctgttaaga ttatcggtga caacaccgac aaacactgtc aggcttactt ctcttacgac
     1321 tccaagaagt cgggtggttt cacttgttct cacttgcgtt tcggtgatac tccgatccgt
     1381 tctacttact tggtaaatac tccgaacttc gttgcttgtc acgttcaggc ttacctgcac
     1441 atgtacgacg taacacgtgg tttgcgtaag aacggttctt tcttgctgaa taccatctgg
     1501 gaaggcgaag aactggctaa gaacctgcct aacaaggtga agaaatactt tgcacagaac
     1561 aacatctctg tatactatat caacgcaact cagattgcaa tggaaattgg tttgggcaac
     1621 cgtaccaata caatccttca gtctgcattc ttccgtatca caggcgtaat ccctgtagat
     1681 caagctgttg aacagatgaa gaaattcatc gttaagtctt acggcaagaa gggtgaagac
     1741 gttgttaaca agaactacgc tgctgtagac cgcggtggtg aatacaagac tctgactgtc
     1801 gatcctgctt gggctaacct gccggatgat gcaaaagcag aaaacaatga tcctgctttc
     1861 atcaacgaag tagttcgtcc gatcaatgca caggacggtg acttgctgcc ggtatctgca
     1921 ttcaagggta tcgaagacgg tacttggtat caaggtactt ccaaatacga aaaacgtggt
     1981 gtagctgcat tcgttcccga atggaatgct gaaaactgta ttcagtgtaa caagtgtgct
     2041 tacgtttgtc ctcacgcttc tatccgtccg ttcgtactcg atgctgaaga gcagaagggt
     2101 gctaagttcg agcaactgaa agctgtaggt aaagcattcg atggtatgac attccgtatt
     2161 caggtagacg ttctcgattg tctgggttgc ggtaactgtg ccgacatctg tccgggtaat
     2221 ccgaagaagg gtggcaaggc attgaccatg aaacaccttg aaagccagtt ggccgaagct
     2281 gataactgga cttactgcgc tgaaaacgtg aagagcaaac aacacctggt agacatcaag
     2341 gctaacgtga agaactctca gttcgcaact ccgttgtttg agttctcagg cgcttgctcc
     2401 ggttgtggtg aaactccgta cgtgaaactg atttctcagt tgttcggtga ccgtgaaatg
     2461 gttgctaacg ctacaggatg ttcttctatc tactccggtt cagttccttc tactccgtac
     2521 actatgaacg aaaagggtca cggtcctgca tgggctaact ccttgttcga agacttctgt
     2581 gaatttggtc tgggtatgga actggctaac gaaaagatgc gtgcccgtct ggtgaaagta
     2641 atgaacgaag ctatcgcttc tgattgctgc ccggctgaat acaaagaagt atttgctgaa
     2701 tggatcaaca atatgctgga tgcagaaaag actaaggaac tggccgaaaa gatcattccg
     2761 atggtagaag ctgctaaaga taaatgcaac cactgcaagc aaatcgctga tctgcaacaa
     2821 tatcttgtta aacgcagcca atggatcatc ggtggtgacg gtgcttctta tgatatcggt
     2881 tacggtggtc ttgaccatgt aatcgcttcc ggtaaggacg ttaacatcct tgtattggat
     2941 actgaggttt actctaacac aggtggtcag tcttctaaag ctactccggt aggcgctatc
     3001 gctaagtttg ctgctgcagg taagcgtgta cgtaagaaag acctcggtct gatggctact
     3061 acttacggtt atgtatatgt tgctcagatt gctatgggtg ctgaccaggc tcagactctg
     3121 aaagctatcc gtgaagctga agcatatccg ggaccatcac tgatcatcgc ttacgctcca
     3181 tgtatcaacc acggtctgaa agccggtatg ggtaagagcc aggaagaaga agaaaaggct
     3241 gttaagtgcg gttactggca cttgtggcgt tacaaccctg ctttggaaga agaaggcaag
     3301 aatccgttcc aactggatag caaagaacct aactgggaag acttccaagg tttcttgaag
     3361 ggtgaagttc gttacgcttc tgtaatgaaa caatatcctg ctgaagctga agaactgttt
     3421 aaagctgctg aagaaaacgc taaatggcgt tacaacagct acaaacgtct tgccagagaa
     3481 aactggggag ctgatacagc tgaataataa gtagaaatac tttgtacata ataaaaggca
     3541 ggaatcctgg aaacagattc ctgccttttt tgtttatatc ttagaagtaa cgattacttc
     3601 tcacgaagat attcattaaa actctaaaga tatgatcgga tttgttattt ggattatcgg
     3661 tttgatactg actttcagag ctgccataga gatttggaat ataaatgcgg ctgtagagaa
     3721 aagacttata gcgattgtat taatcgttct taccagctgg ctgggactac ttttctacta
     3781 cttctatggt aaagaaagaa tggcgggatg gttgaagtag tgtttgcata tcaatctttc
     3841 tcaggaatcc aactgttcac cagttcctga tgttcttcca tccattgacg ggcagcctgt
     3901 ctttccgttg tctgcgcctc ttccagagca gtcattaagg agctgatttc cgcatctgtc
     3961 agacgaatgt tgcccaaaag ttcggcagca aaagggtctt tctcgctaaa acctttccat
     4021 gctatggtat gaatggattc cgtatttcca tatatcagct tcgggtcctg aagaactttc
     4081 agcttgaaac ggtcgaacat ccagtgaggc gtccatcccg tcacgacaat ccagtctttc
     4141 ttatcaatcg ctttctttag ggaagcagtc atggcaggtc cgctcgaagt catcagttta
     4201 taatccaatc catagtcttt gatggcctga tcggtagctt tcataatacc ggctccggca
     4261 tcaataccga caatctgacc ggagaaacgt tccttttccg cgttcagttc ttcgattgag
     4321 ttgatcgtaa cgtaatccgg aaccaccagc ccgatacggg caccatcata aatatccccg
     4381 ataacttcga gtttatcccc gtattgtttc atataatctt ccatagtgac aggcatccag
     4441 acatccataa atacgtctgc tttcttacgg gagatagagg taaatatagg tgcaaggtcg
     4501 gcattcagca actttacatc gtacccctga tcttcaaaaa tcgctttggc aaggtttgtc
     4561 attgcaatac cttccgacca gttggcataa gcgatactta tcttcttact ctttccgttg
     4621 tctccgcagg aaacgaaggt taagagtatg ccggcaataa acattgccgc aatcattttt
     4681 atcttattca ttgattattc ctttctttgg tgtgattctt atttcttttt actttttctg
     4741 ttatctgcca taccctgagt gatgcggtcc agcacgatcg ccaatatcac gactgcgata
     4801 ccgccttcaa atccgagtcc gattttcatt tgggtgatac ctttcagcac gatttctccc
     4861 aatcctccgg cagaaatcat ggcagcaatc actaccatcg aaagtgacat catgatcgtc
     4921 tggttgattc ccgtcagaat agtaggcaac gccaaaggca attgcacctt ataaagaagc
     4981 tgccagggag tagctccaaa agagcgggag gcttctacta cgtttttagg aacctgacga
     5041 atgcccagac cggtcagacg aaccacagga ggcattgcaa agatgatggt ggcaaaagct
     5101 cccggcacag ttcccaatcc gaagaataga acggcaggaa tcagatagac aaaggcaggc
     5161 attgtctgca taaagtcgag gacagggcgc attatcttgt tacaacgatc actgttggca
     5221 gtccagattc ccaacggaac gcctaaaagc aatgccagac aagtggaaga aagtaccaat
     5281 gccaatgtct gcatcgtttc ttcccaaaag cccatgccgt aaataagcaa taaacccaag
     5341 agggtaaata cggctgtccc cttacccgac ttaaaccagg cgagcgcagc cagcactgca
     5401 attgtgatat aaaaaggtat tccaaacagt acgtgctgga atccgtctat gaatcctccg
     5461 atccccatgc tgagagcatc aaaaaaggaa gcaaaatgtt ctgtgagcca attaatggca
     5521 gtctctatat attgtccgat atttatcata attctattgc gttttgaatg atttcattaa
     5581 tttcttcttt atcttttccc gttacttcga taatcaatga ggaaagtggc actacgcctt
     5641 caaactcccg attctcattt acgacccaga ttggcgagtt cgtttttgtc atcaacggaa
     5701 gaatatcttc cagcaccgta tcccccagta ccgaatgaac ttcatgtctt actacggact
     5761 cgatggagcg gatttgctct tttcgcagtt tcagcaagtc attcaaccgc acctctccta
     5821 ctaacagatt attggaatcg actaccggaa gaacggtcag attccgttcg cgcatcttac
     5881 ggatcagcac ctccgggcct tctttcttca aacgtgccac tatgggttta tctaccataa
     5941 cggaagaagc tgtaattatc ttgcttcgat ctacattctc cacaaatcgt tctacataag
     6001 cgttggcagg ttcggtcagg atttcttccg atgtaccgat ttgtacaatt tctccatcct
     6061 tcatgatagc aatccggtca cccaatttaa tcgcttcact caggtcgtga gtaataaaga
     6121 caatcgtttt tttcatcttc gactgcaaag tcagcagttc atcctgcatc tgtacgcgaa
     6181 tcaaaggatc gagtgccgag aaggcctcat ccatcaacag gacttcggga ttattggcca
     6241 aagcccgcgc cagcccgaca cgctgctgca tcccacccga caattcactg accatctgat
     6301 tctcgtagcc tttcagcccc accagttgca tactttccat cgctttctgc tcccgttctc
     6361 cctttttaac tccctgtagt tcgagtccga aagctatatt atgcaagaca gatcggtgag
     6421 gaagcagacc gaagttctga aagaccatag ccagttcttt ccggcgaatc tgcaacagtt
     6481 ctttgtccga cactttggct atgtctgttc cattgataat cacttctccg gaagtagggc
     6541 gtatcaaacg gttgatgcag cggagtaaag tggactttcc actaccggac agccccataa
     6601 tgacgaatat ttcgccttca ttaatggaaa gattcgcatc tttcaccgca accgtacatc
     6661 cggtcgcttt caatatttca ctttttgttt taccttcttt caacatcttc aaagccttct
     6721 gcttctcatt gccaaaaacc agatagagat ctttaatttc tattttactc atacaataaa
     6781 atggtttagg ttattaaaat aatatacaca gcaagacaag aacaaacgat aacaggaatc
     6841 tttctttata tcgtataaag ttctgattta aatacgggac aaataacaat gaatcccgaa
     6901 ataattaata aaatgattat tgacagactg agtaattaaa aaaggaatag aatttgataa
     6961 gataatcctt tcaacgaata gcaaaaaata gcatttttat gtataaaaac agcctgtttc
     7021 agtatcttgc tggcacaaag atacaaaaaa cagattaaac atgcaaatta tattcaaaat
     7081 ccggggcata cagagggctt tatttgtaat gatatggaaa gttttcgggt aatattcccc
     7141 tatcactcag caaaatagaa caaaccggca gataaatata aaataagttt gaatatttca
     7201 cctaaacacc gtatatttgg cgtcaataac taaactagat ttatatgttc aacagggcta
     7261 ttacaatttt cctggggaag gataattgtc attacacaac aaaagaaaaa caaacaggta
     7321 ctgccacact agacgacaaa agccaagtac agttccttag taaaaagaac cccaaaatgc
     7381 cgtttttcta tagtcggcgg aatctctaca tgataggttt cctgctcgct tttatagtga
     7441 ctctgctcga atttatgcga ggacggcatc aaaactttat ggtcttctca gacgctactc
     7501 aattcttctg gcaaggcatc agcccataca caaccgaatt tgtagaagct cacggacgct
     7561 acttccttta ttctcctgtt ttcacggtat tgttcgctcc gtttgcgtat ctgcctgcat
     7621 ggctgggacc tttcgcgtgg aatctattca attattcatt gttctttgta gcgatcttca
     7681 cgctgcccca accattcacc cagcaacaga aatgccgtat gttccttttt ctgttactga
     7741 ttttaggaca aagtttactt tcatttcagt ataacataac ggtagcctat ttattcttat
     7801 tcgcctatac gttattggaa aaagaccggg gatttctagc tgttctgtta atcatgattt
     7861 cgggatgtac caaagtatac ggaattttcg aactggcatt gttgctgtgc tatcctcacg
     7921 tatggcgtaa ctttggctat gccgttgcaa tgggcatcgt attgcttgcg ttaccgttaa
     7981 tcaaaatagc tcctgcagat ttgctcccct attatgaaga atggtgccat agtcttgctg
     8041 ttcatcaatc caccggagct tatgattcat ttttctatgc ccgccccatt gcagcatgga
     8101 cattgccaca tttccgtgca cttcagatag gaatgctcgg tctgctgact ctgctctttt
     8161 tggggaattt ccgcaaatgg tcgtcttttg ccttccgtgc ccaggctttg ggtatcttaa
     8221 tgggatgggt ggtattattg agtgactctg ccgaaaagca tacctatatc atagcattgg
     8281 caggtttcat gctctggtat tggagcaggc caacacgtac cgcaacagac aagattctat
     8341 tttggtgctg ttttgtgctg ttatgtatcg ttcctatcga catatttgtc cctgttccca
     8401 tcagagattt catcaccagg accttatggc ttcatgtatg ggttttcttt attgtatgga
     8461 tacggatgat atggcttacc ttccttgcat ccttcattca tccacgtgcc acaaatgttc
     8521 tttcagatta acgcatccgt tagctttgaa agaaacttct tctgccagca agagttgttt
     8581 ttgttccacc caaccgggca ccatccttcc ggcggaattt acaactctat ggcagggaat
     8641 ggataattca tccggcactt ctttcaaagc acgccccacc atccgcgagc attggggtgc
     8701 ccccaagagc aaagcaatac ctccataggt agatactttt cctacaggta tctgggatac
     8761 gacttcgtac acttccttcc gaaaggattc ggaaaagctc tctttatcta ctttataatc
     8821 tttcatatat ccctctttac gatctcaatg aaatcatcct ttccttttca ggaagtctgt
     8881 cgggctctct ccgaactgct ctttatagca cttggtgaaa taagaaggtg aactgaaacc
     8941 gacttcataa ccaatctccg ctacggtcat gtccgaagaa gcaagcaaag aagctgcctt
     9001 cttcaaacgg gcgatacgga gcaattcatt cggagagtag ttagtcaacg atttaatctt
     9061 gcggtaaagc tgcacacggc ttagtcccat atctttgccc aagtcctcca cattcaaacc
     9121 ggagtctccc attttctctt caatcaatga cttgaatctt tctacaaaat ccttgtccat
     9181 atcgcagaca tcttccttcg ccaatgtctg cccgtcacca aagaactgtt tcagacgacg
     9241 gtgagaatca atcaggttgc ggacacgtgc cagcaacagt tgtgaactga acggctttga
     9301 aatataagaa tccgcaccac cgtcatatcc ctgaatacgc tgttcgtcca gtgaacacgc
     9361 tgtcagcaga ataaccggaa tatgacaggt ctgtaactca cttttcagcc ggcggcaaca
     9421 ttcaatgcca tcaatgcccg gcatcatcac atcggaaatg atcaggtccg gaacatactt
     9481 catagcctta cggattcctt cggagccgtc tgccgcttca atcaccatat aatctgtatg
     9541 caacagcgta tggacatacg aacggatatc ctcattatca tcaataatca gtacggacga
     9601 tttggaagag tcatatcctt tttccagttc ttcctcttcc gccaatagaa catctgttgt
     9661 acgggaatcc gcagaaacaa gggtggtatc cggttcggca gcaacagcct cgcaagactg
     9721 tacaggcagt tcaacggtaa agaccgtacc ctgtttctca tcgctctcta cagagatcgt
     9781 accaccgtgc atttctacga aggcttttac caatgccagt ccgattcccg aaccggtatg
     9841 gtgcatatcg attttataga aacggtcgaa tacattgcgg atatgttcgg cagaaatcat
     9901 agaaccggta tttgccaccg tgaaacgtat ccatcgtttg tcctctttac taagggaaga
     9961 cagacgaacg gcaattcttc cgttttccgg tgtaaactta aaggcattgg acagtagatt
    10021 gaaataaatg cgttccagct tctccatgtc tgccagtgta tgataatccg tatccggcat
    10081 attatcaaaa gaaaaatgga tatgtttctt acgggctgcc gcctgaaaag actcattcca
    10141 tccttcgaaa gaagaaagga catccaccgt aaccggagta tattccatct tgccattttc
    10201 atatttacgg aaatccagaa tctgattgac cagacgcaga agaatgttca cattccgctg
    10261 aatcagcatg agcatccggt gctgatctcc gctcagtgtc ttgtccgcca acaaatgttc
    10321 taccggatcg gcaactaatg tcaacggagt acggaagtcg tgagaaatat tggtgaagaa
    10381 taccagcttg gcatgggtag cttcttctag ttgatgagaa agttgtatca attggtcacg
    10441 ctgttcttcc aattgctgtt tctgtttaaa aagctcttta ttcaagcgat tcttagagcg
    10501 gagtgattta taaacgacca ataataagcc ggctaccaat aaaaggataa tcagactgcc
    10561 gtataaaacg acctgttgtg tagctacctg agaaaggtat ccaccgatac gtccgttgag
    10621 cgtttcaatc tttttgtcga gttcggaaat gtgtgtggtc tgcaattgca tgacgtgcgc
    10681 gttggtacgg tcgacaacag cggtattcat caccgtttct ttgggatagg gtttcttctc
    10741 cagaatatcc atagccagtt gcagtacctt atcgccattg gtcggataga taaaggtagc
    10801 atccagcaca ctgtccagaa ccagttccag cccgtttccc ttacccggca aggcatctat
    10861 gccgacaaaa atcatttcct tctcccgccc tgctatcttt gctgcctgat aggcacccgg
    10921 agcgatacgg tcattatgag catacacagc atcaatctta ggatgcctcc gaagcatact
    10981 atccatttct atctctgccg gaccacgttc ccaagcagca tccgctttat caatcagctt
    11041 tatatccggg aatttactga tggcagccat aaatccctga tgccgttcca ttgcaggagt
    11101 cgaaccgctc aatcctgtca gttctactat atttcccttc cctttcagac tggaggcaat
    11161 atagtttcct accgaacgac cgatttcata attatcggct ccgatatagg cagtatattt
    11221 atccgaaaga atcttccggt ctacaagaat aacggggatg cctttctgat aagcttcttc
    11281 tacaatcgga gtcataggag cagcttcgtt agcggaaata atcagcagat cgactccttc
    11341 gtccataaaa taatggacat cttccgcctg cttactgtta tcatcccctg ccgaacggat
    11401 ttccaccgaa acaccattat aaaacatcgc ttcccgaaga atctcatcat tcatcttatg
    11461 tcgccatgaa tcatcgctgc attgggccac cccaatacga aaacggggtg tatcctgccg
    11521 gcaagccgtc atcccgatta aacaaaacag caccagcatc cacttcagat atctcatcgt
    11581 cttcatccat ctcatcattt cgtagttctt tctgtaatcc aattaagaac aaaaataaga
    11641 aataatactg taaagttctc taacttcagc tatttattat tctaaaaaga aggaaagcag
    11701 tcctctttca gactatcgga aagtattaac aaaagtataa agcgtaaaac aaacacttaa
    11761 tcaatgttat aaaacatagc gttttacttg gataatttgc agatttcaca gaagtccgta
    11821 tctttgcatt gtgtttttca tagtattaga tttaaggtta acaaaggttg gagcaaggcg
    11881 ttgctccttt ttttatgccc tgacctttca tctaccggtt agttttcatc ccattccttt
    11941 tccagtttac catcaatagt gtagcgtttc catcgtccca cacggcgacc attcttatat
    12001 tccccacatt cacgaagctg gtcattcttt acataacgag cttcgaacgg tccgttctgc
    12061 cgtccgttca cataggtaga agtttcccaa taatcaaagc ggttgctcac catcagccgt
    12121 cgttccttgc catgcaatct gccggcctga taggtagctt catatctcaa ttcaccattt
    12181 tccagattat attcacggta taaaccgtct ttacggtcgt tcttcatata atattctttc
    12241 tgccttaccc cacttccgtt ggcaaatgag acatggagtc catcttcttt tccatccaga
    12301 taggtttcaa tcatcagtgt atcgccgctt tcggcaaaag tagtccaccg accattcttc
    12361 tttccattct tataactacc cagtatacgt ggcgagccaa acgtaaacac ggacgaatat
    12421 tcaccgtcct gcaaaccttc ttcattgaaa taaacggtct catacaaatc ataagtacct
    12481 ttcagaaaag tatattgttt gcctacctgc ttcccgtcct tgtaattatg ctctttccgc
    12541 aaagtaccgt cagaatcgta tgagagctgt ttcccgtgct ctttccccat ccggaagttt
    12601 ctttcacttt ccacttttcc ggtagtaaag taacttttgc tcgtaccgtc cagcttacct
    12661 tccttatagg atttttcttc ttttagctta ccgtcaaact tggagttaat cttgaagaga
    12721 ccatccttcc gtccttcttt ataacttcct tccgttatta atatattgtc tacatattct
    12781 ttgtatccgc catcatagaa accatcctta aaagatgcca gcacataggc ggaatgataa
    12841 ccatctatga tgcgatgttc gccattcaat gctttttccg ttttcagttc ctgaaacaac
    12901 agtctgccat cgcctacatt gacaacggat acctgatcga tcttatattc cttttgcgca
    12961 aacaaaggaa gagcaagata taaaaacaaa aatacgttcc agctttttga tctgaggaag
    13021 tttgaaatgt gtttcataaa gtagttttct ctttttaatt tattatttaa agacctgccg
    13081 caaagatagg caatcggctt ataaaacaag gaaagaaaga gggggacaat tagaaaaaag
    13141 agcatctgtt attatcactc taataattaa cagattaatt attaaatcaa aacacaggga
    13201 agggggacat ttactgaaat aagaaacaga aaaccggaga tataccctga attgcagggt
    13261 atatctccgg tttttgtatt taaagagatt ctacaacaat ctgtctttca gaacaaccgg
    13321 aagttcgggc attgcaccgc tctgcgtaca aacataagcg gaaacttcga cagccagctt
    13381 atgagcttcg ggaacggact tgccattcag aatggaagca cagaaagcgg cagtaaagga
    13441 atcccccgct cctaccgtat cggctaccgg aaccttcggc gtttcctgaa aagaaacgac
    13501 tcccgga
//
