LOCUS       c00004_gnlPro..         5828 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MAODONAD_4.
ACCESSION   c00004_gnlPro..
VERSION     c00004_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 08:44:42
            Original ID  :: gnl|Prokka|MAODONAD_4
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5828
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5828
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[329:4459]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      330..4459
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..5828
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..5828
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             330..2132
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_1"
                     /sec_met_domain="ILVD_EDD (E-value: 1e-217, bitscore:
                     712.2, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKQLRSSFSTQGRRMAGARALWAANGMKKEQLGKPIIAIVNSFT
                     QFVPGHVHLHEIGQLVKKEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPTVFVSGGPMEAGELDGQHLDLID
                     AMIKSADESVSDEEVSKIENRACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     ANRTQLFKDAAKLIVENTYKYYRDGDESVLPRSIATREAFLNAMTLDIAMGGSTNTVLH
                     LLAIAHEAEADFKMDDIDMLSRKSPCLCKVAPNTQKYHIQDVNRAGGIMGIMGQLAKAG
                     LIDTSVVRIDGMTLGEAIDKYDITSPNVCEEAIKKYKSAAAGKFNLVLGSQDVYYKELD
                     TDRAEGCIRDIEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQEA
                     ACNGILGGKVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHISPEAAAGGNIGKIKDGDIIEINIPERTINVRLTDEELAARPMTPVTRERY
                     VPKSLKAYASMVSSADKGAVRLID"
     CDS             2188..3885
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_2"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4e-48, bitscore:
                     151.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKDIISGGEALMRSLEYHGVKTIFGYPGGSIMPVFDALYDHRET
                     LNHILVRHEQGAAHAAQGFARASGEVGVCLVTSGPGATNTITGIADAMIDSTPIVVIAG
                     QVGTAFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVPWAVARAFYIAKSGRPGPVVLD
                     FAKNAQVEKAEYMPAKLDFIRSYVPVPETDPEAVKAAAELINGAERPLVLVGQGVELGN
                     AQQELRAFIEKADMPAGCTLLGLSALPTEHPLNKGMLGMHGNLGPNMNTNKCDVLIAVG
                     MRFDDRVTGNLATYAKQAKVIHFDIDPAEINKNVHADVAVLGNCKETLSAVTALLQPNE
                     HKEWLDSFLPYEQVEEEKVIRPELHPMGDTLSMGEVVRAVSDATNHEAILVTDVGQNQM
                     MSARYFKYSKDRSMITSGGLGTMGFGLPAAIGATFGRPDRTVCVFMGDGGLQMNIQELG
                     TIMEQKAPVKIIVLNNNFLGNVRQWQAMFFNRKYSFTPMLNPDYIKIASAYDIPAKRVF
                     TREELADAIDEMIATDGPFLLEACVIEEGNVLPMTPPGGSVNQMLLEC"
     CDS             3899..4459
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_3"
                     /sec_met_domain="ALS_ss_C (E-value: 1.7e-19, bitscore:
                     58.4, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKTLYTLIVHSENFAGLLNQVTAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTDKDTIEKVVKQIEKKIDVLQAHYFTEDEIYFHEIALYKVSMPEFQSQPE
                     ASKVIRRYNARIVEVNPVFAIVEKNGISEEITSLYEELSALNCVLQFVRSGRVAITTSC
                     FERVNEFLADRETKYNLSKKEEK"
     CDS             4460..5203
                     /locus_tag="ctg4_4"
                     /transl_table=11
                     /translation="MSDDKKIGSYKFIAEPFHVDFNGRLTMGVLGNHLLNCAGFHASER
                     GFGIATLNEDNYTWVLSRLAIDLEEMPYQYEEFTVQTWVENVYRLFTDRNFAIIDKDGK
                     KIGYARSVWAMINLNTRKPADLLTLHGGSIVDYVCDEPCPIEKPSRIKVATDQPCAKLT
                     AKYSDIDINGHVNSIRYIEHILDLFPIDLYKSKRIQRFEMAYVAESYYGDELSFFEEEV
                     SENEYHVEIKKNGCEVVCRAKVKFV"
     CDS             5221..5805
                     /locus_tag="ctg4_5"
                     /transl_table=11
                     /translation="MKKIVFLLLLCVACCMNAQEFHLIPKVGLNLANTTGEVDSKVRSG
                     LNIGLGGDVMLTERFGIETGVYYSMQGSKYKGGGVSYTDKLDYINVPVYAKEFIYKGLY
                     VFGGPQFSFNVNSENKSSSDYGSTVIGMNVIRKFDCGVGLGAGYQFERGLLISLNYNIG
                     LINVNKSWASDSNPKANNSVVQLNVGWRFAL"
ORIGIN
        1 aaatagttgg gaatatagga ttttgaatga taaatacata tttaaagatg ggctttgctt
       61 acaattattt tgttttaggt gatttttttc ttcaatttgt ttggagttta taaaaaagca
      121 cttacctttg cagcaatcaa agaatagaaa atagaagtta tgaataatca tacatcaatt
      181 aacctggcag tcctgcatat tattcgcgtc gtggtgattc catcaagagc gtgagaaagg
      241 ttatgtatgt attcgtacag atagaagata tgatttagag cctttctcac tacagtgagg
      301 aaggctcttt acttaaaagg aatattgaaa tgaaaaagca gttacgcagt tcgttcagca
      361 cacagggtcg ccgcatggca ggcgcccggg cactttgggc agccaatggt atgaaaaaag
      421 agcaattagg caaacctatc attgccatcg tcaattcgtt tactcagttt gtgccgggac
      481 atgtacatct acatgaaata ggtcagctgg tgaaaaaaga aattgagaag ctgggatgct
      541 ttgctgcgga attcaatacg attgccattg atgatggtat tgccatggga catgacggaa
      601 tgctttattc ccttccttcc cgggatatca ttgccgatag tgtggaatat atggtgaatg
      661 cccataaagc ggatgccatg gtatgtatca gcaattgtga caaaatcact ccggggatgt
      721 tgatggcggc tatgagactg aatattccta ctgtatttgt atccggaggt ccgatggaag
      781 ccggtgaact ggatggacag catttggacc tgattgatgc gatgattaag tcggccgacg
      841 aaagtgtgag tgatgaagaa gtctccaaga tcgagaatcg ggcctgtccc acttgcggat
      901 gttgttcggg aatgtttacc gccaattcga tgaactgcct gaacgaagcg atcggtctgg
      961 ctctccccgg aaacggaacg attgtggcga cccatgccaa ccgtacccaa ttgttcaaag
     1021 atgctgcgaa actgattgta gaaaatacct ataaatatta tcgggacggt gatgaaagcg
     1081 tacttccccg gagcattgcc acccgtgagg cattcctgaa tgccatgacg ctggacatcg
     1141 cgatgggagg atctaccaat acagtacttc acctgctggc gatagcccat gaagcggagg
     1201 cggactttaa aatggacgat atcgatatgc tttcacgcaa gagcccatgc ttgtgtaagg
     1261 tggcgccgaa tacacagaag tatcatattc aggatgtaaa ccgtgccgga ggtatcatgg
     1321 ggattatggg acaacttgcc aaagccggat tgatcgatac gtctgtagtg cgtatcgacg
     1381 ggatgacatt gggtgaggcg atagataaat atgatataac tagcccgaac gtatgtgaag
     1441 aggctattaa aaagtataag agtgcggctg ccggaaagtt caatctggtg ctcggctctc
     1501 aggacgtcta ttataaagag ctggatacgg accgtgccga agggtgcatt cgtgacatag
     1561 agcacgcata tagcaaagac ggaggactgg ccgtactgaa aggaaatatt gcccaggatg
     1621 gttgtgtggt gaaaacggcc ggagtggacg agagcatctg gaagtttacc ggtccggcaa
     1681 aggtgttcga ttcacaggaa gcagcctgca atgggatact cggaggaaaa gttgtcagcg
     1741 gagatgtagt cgtcatcacg cacgagggtc cgaagggagg tcccggtatg caggaaatgc
     1801 tttatcctac ctcttatatc aaatcgcgcc acttgggcaa ggagtgtgcg ctgataaccg
     1861 acggccgttt cagcggaggt acatcgggac tcagcatcgg gcatatctct cccgaagcag
     1921 cagccggagg taatatcgga aagattaagg atggtgatat catcgaaatc aatatccccg
     1981 aacggactat caacgtgcga ctgaccgatg aagaactggc tgcacgtccg atgactccgg
     2041 tcactcgtga acgctatgtg cctaaaagtc ttaaagcgta tgccagcatg gtaagctctg
     2101 ccgataaagg agcggtgaga ctgattgatt aaccacagag ttgtttcaat cgtaaattgt
     2161 aaatcgtaaa atcgtaaatt ttagtacatg agtaaagata taatttcagg cggtgaagca
     2221 ttaatgcgtt ctttggaata tcatggtgta aagacgatct ttggttatcc cggaggatct
     2281 atcatgcccg tattcgatgc cttatacgat catagagaga ctttgaatca tattttggtt
     2341 cgccacgaac aaggggcggc acatgcggct cagggatttg cccgtgcttc gggtgaggtc
     2401 ggagtttgcc tggtgacgag cggccccggt gctaccaata ccataaccgg tattgcggat
     2461 gcaatgatcg acagtacacc gattgtagtc attgccggac aggtgggaac agcttttttg
     2521 gggacagatg cttttcagga ggtcgacttg gtaggcatca cgcagccaat tacaaaatgg
     2581 agttatcaga tccgtcgtgc cgaagatgtg ccatgggcgg tggcccgcgc cttttatata
     2641 gcgaaaagcg gacgcccggg accggtagtg ctcgactttg caaaaaatgc ccaggtggag
     2701 aaagccgaat atatgcctgc gaaactcgat ttcatacgca gttacgtgcc tgtacccgag
     2761 actgacccgg aggccgtgaa agcggctgcc gaattaatta acggtgcaga gcgcccgttg
     2821 gtattggtgg ggcaaggtgt ggaactgggc aacgcacaac aggaattgcg tgctttcatc
     2881 gaaaaggcag atatgcccgc cggatgtacg ttgttgggac tgtcggcttt gccaaccgag
     2941 catcctttga acaaaggtat gctgggaatg cacggtaatc tcggaccgaa tatgaacacc
     3001 aataaatgtg atgtcctgat tgctgtcggc atgcgttttg acgaccgtgt gaccggaaac
     3061 ctggctacgt acgccaagca ggcgaaagtg attcattttg atatcgatcc ggctgaaatt
     3121 aataagaatg tacatgcgga tgtagcggtt ctgggtaact gtaaagagac gctctctgct
     3181 gttacggcat tgctgcagcc caacgagcat aaagaatggc tggatagttt cctgccttat
     3241 gaacaggtgg aagaagaaaa ggtaatccgt ccggaattgc atccgatggg agatacgctt
     3301 tcgatggggg aagtggtgcg tgcggtaagc gatgcgacca atcatgaagc gatattggtg
     3361 accgatgtcg gtcaaaacca gatgatgtct gcccgatact ttaaatattc aaaagaccgg
     3421 agtatgatta cttccggagg acttggtacc atgggattcg ggttgccggc tgctatcggt
     3481 gcaacctttg gccgaccgga ccgtacggtt tgtgtattta tgggtgacgg tggtctgcaa
     3541 atgaacattc aggagttggg aaccattatg gaacagaagg caccggttaa aattatcgta
     3601 ttaaacaata atttcctggg caatgtacgc caatggcagg caatgttctt caaccgtaaa
     3661 tactcgttca cacccatgct gaatcccgat tatattaaga ttgcttctgc ttatgatata
     3721 ccggccaaaa gagtctttac ccgtgaagaa ctggctgatg cgattgacga gatgattgcg
     3781 acagacggtc cgttcctgtt ggaagcttgt gtgattgaag agggaaatgt gttgccgatg
     3841 acccctccgg gaggttcagt taaccagatg ttgttggaat gctaataagt taggaattat
     3901 ggataagaca ttatatacat taattgttca ttcagagaac tttgccggat tgttgaatca
     3961 ggttacggca gtatttaccc gtcggcagat taatatagaa agcctgaatg tttcggcttc
     4021 atctatcaag ggggtgcata aatatactat tacggcttgg accgataaag atacgataga
     4081 gaaggttgtc aaacagattg agaagaagat cgatgtgctt caggcacatt atttcactga
     4141 agatgaaatc tattttcatg aaatagctct ttataaggtg tctatgcccg aatttcagtc
     4201 acagccggaa gcttcgaagg tgattcgtcg ctataatgca cggattgtgg aagtgaatcc
     4261 ggtatttgcc atcgtcgaga aaaatggaat cagtgaagaa attacttctc tctacgaaga
     4321 gttgagtgca ttgaattgtg tgttgcaatt tgtgcgttcg ggacgtgtgg caatcactac
     4381 cagttgcttt gaacgtgtga acgagtttct ggcagatcgt gagaccaaat ataacttaag
     4441 caagaaagag gaaaagtgaa tgagtgacga taagaagata gggagttata agtttattgc
     4501 ggagcctttt catgtagatt tcaacggacg tttgacaatg ggggtgcttg gcaaccatct
     4561 gttgaactgt gccggctttc atgccagtga acgcggcttt ggaatcgcta cattgaatga
     4621 ggacaattat acatgggtat tgtctcgtct ggccatcgat ctggaagaga tgccttatca
     4681 atatgaggag tttactgtac agacatgggt ggagaatgta tatcgtcttt ttactgatcg
     4741 taattttgcc attatagaca aggacggcaa gaagatcgga tatgcccgtt cggtatgggc
     4801 catgattaat ttaaataccc gcaagccggc tgatttgctg acgttgcatg gcggtagtat
     4861 tgtggactat gtatgtgacg aaccttgtcc gatcgaaaag ccttcgcgta tcaaagtggc
     4921 tactgaccaa ccttgtgcta agttgacagc taaatacagc gatatcgaca tcaatggtca
     4981 tgtgaacagc attcgttata tagaacatat cctcgatttg tttccgatcg atttgtataa
     5041 atcgaaacgg attcagcgat ttgaaatggc ctatgtggca gaaagttatt atggcgacga
     5101 gctttctttt tttgaagagg aagtaagtga gaatgaatat cacgtcgaga ttaagaaaaa
     5161 cggctgtgaa gttgtatgcc gggcaaaagt gaagtttgtg tagtttaaaa tgtgattaaa
     5221 atgaagaaga ttgtttttct tttgctgctc tgtgttgctt gctgcatgaa tgcacaggag
     5281 tttcatctga ttccgaaggt cggtttgaat ctggcaaata ctaccggaga ggtggattct
     5341 aaagtgcgtt ccggactcaa tatcggtctg ggaggtgatg tcatgctgac cgaacgcttt
     5401 ggaatagaaa caggagtgta ttactccatg cagggaagca aatataaagg gggcggagtc
     5461 tcttatacgg ataaactgga ttatatcaat gttccggtat atgcgaaaga atttatatat
     5521 aaggggctgt atgtgtttgg agggccgcag ttcagtttca atgtgaactc agagaacaaa
     5581 tcatcctccg actatggtag cacagtcata ggcatgaatg tgattcgcaa gtttgattgt
     5641 ggagtggggc ttggagccgg ttatcagttt gaacgtggtc tgctgatctc tctaaactat
     5701 aacatcggac tgattaacgt aaacaaatct tgggcaagcg actctaatcc taaagcaaac
     5761 aatagtgtgg tccagctaaa tgtcggttgg cgttttgcac tgtaagataa agaatataag
     5821 tttaatta
//
