LOCUS       c00835_gnlPro..         3448 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AAPILHEA_835.
ACCESSION   c00835_gnlPro..
VERSION     c00835_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 12:42:49
            Original ID  :: gnl|Prokka|AAPILHEA_835
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3448
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3448
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:2630]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..2630
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..3448
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..3448
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             3..203
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg835_1"
                     /sec_met_domain="ILVD_EDD (E-value: 8.8e-17, bitscore:
                     48.8, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="GNIGKIVDGDIIEIDIPARKINVRLTDEELAARPMTPVTRDRYVP
                     KSLKAYASMVSSADKGAVRII"
     CDS             328..2022
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg835_2"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.2e-48, bitscore:
                     152.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDLITGAEALMRSLEHQGVTTIFGYPGGSIMPVFDALYDHQNIL
                     NHILVRHEQGAAHAAQGYARVSGDVGVCLVTSGPGATNTVTGIADAMIDSTPIVVIAGQ
                     VGTGFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAVARAFYIARSGRPGPVVLDF
                     AKNAQVEKTKYEPTKVDFIRSYVPVPDTDEETVQAAAELINNAERPLVLVGQGVELGNA
                     QSELREFIEKADMPAGCTLLGLSALPTEHPLNKGMLGMHGNLGPNINTNKCDVLIAVGM
                     RFDDRVTGNLATYAKQAKVIHFDIDPAEVNKNVKVDVAVLGDCKETLASVTKLLKKNTH
                     TEWIDSFKEYEKVEEEKVIRPELHPATNSLSMGEVVRAVSDATHHEAVLVTDVGQNQMI
                     SARYFKYTKERSIITSGGLGTMGFGLPAAIGATFGAPERTVCVFMGDGGLQMNIQELGT
                     IMEQKAPVKIICLNNNYLGNVRQWQAMFFNRRYSFTPMLNPDYMKVASAYDIPSKRVFT
                     REELKEAIAEMLATDGPFLLEACVVEEGNVLPMTPPGGSVNQMLLEC"
     CDS             2073..2630
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg835_3"
                     /sec_met_domain="ALS_ss_C (E-value: 7.9e-20, bitscore:
                     59.1, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDKTLYTIIVHSENIAGLLNQVTAVFTRRQINIESLNVSASSIK
                     GVHKYTITAWTDKDIIEKVVKQIEKKIDVIQAHYFTEDEIYFHEIALYKVSTPAFQENP
                     EASKLIRRYNARIVEVNPVFSIVEKNGMSEDITSLYGELKALNCVLQFVRSGRVAITTS
                     CFERVNEFLDGREAMYNQSKNQ"
     CDS             2636..3379
                     /locus_tag="ctg835_4"
                     /transl_table=11
                     /translation="MSEENRIGTYQFVAEPFHVDFNGRLTMGVLGNHLLNCAGFHANDR
                     GFGIATLNEDNYTWVLSRLAIELDEMPYQYENFSVQTWVENVYRLFTDRNFAIIDKDGK
                     KIGYARSVWAMINLNTRKPADLLTLHGGSIVNYVCDEPCPIEKPSRIKVTSDQSIATLT
                     AKYSDIDINGHVNSIRYIEHILDLFPIELYKTKRIRRFEMAYVAESYFGDELSFFCDEV
                     NANEFHVEVKKNGNEVVCRSKVIFE"
ORIGIN
        1 gaggtaatat cggaaaaatt gtagacggag acattatcga aatcgatatt ccggcccgga
       61 agattaacgt gcgactgacg gatgaagaac tggcggcccg tccgatgact cctgtcactc
      121 gtgaccgtta tgtaccgaag agcctgaagg cgtatgccag catggtaagc tctgccgata
      181 agggagcagt gagaattata taatatagtt ggtgatagtt gataggtaat agttagctgc
      241 gcagcactta gcgcaatgat tgtaaaccat tcattttcaa ctgtcatttc tcaactatca
      301 tttatcattt atcaactatc aactaatatg aaagatttaa taacaggtgc agaggctttg
      361 atgcgctcct tggaacatca gggagtgact accatctttg gttaccccgg tggttctatt
      421 atgccggtat tcgatgcctt gtacgatcat caaaatatat tgaaccatat cttggttcgt
      481 cacgaacagg gagctgccca tgccgcacag ggttatgccc gtgtatcggg tgatgtaggt
      541 gtttgcctgg tgacgagcgg tcccggagca accaatacgg taacaggcat tgcagatgcg
      601 atgatcgata gtacgcctat cgtggtgatt gccggacagg taggaacagg ctttcttggg
      661 acggatgctt ttcaggaagt tgacttggta ggtatcaccc agccaatcac taaatggagt
      721 tatcagattc gccgtgcgga agatgtagcc tgggcggtag cacgtgcgtt ttacattgct
      781 cgtagtggtc gtccggggcc ggtggtactg gactttgcca aaaatgcgca agtagagaaa
      841 acgaaatacg aaccgacgaa agtcgatttt atccgtagtt atgttcctgt tcccgatacg
      901 gacgaggaga ctgtacaggc tgctgccgaa ctgattaata acgctgaacg tccgcttgta
      961 ttggttggac aaggtgttga actgggaaat gcacagagcg aattgcgcga gtttatcgaa
     1021 aaagcggata tgcctgcggg ttgtacgctg ctcgggcttt cggctttgcc gacagaacat
     1081 ccgttgaata aaggtatgtt gggtatgcac ggcaatctgg gaccgaatat caataccaat
     1141 aaatgtgatg tgctgattgc tgtcggtatg cgttttgacg accgtgtgac cggtaatttg
     1201 gctacttatg ccaaacaggc aaaagtgatt cattttgata tcgatcctgc ggaagttaat
     1261 aagaatgtaa aggtagatgt agctgtattg ggagattgca aggaaacact ggcttctgtg
     1321 acgaaactcc tgaaaaagaa cactcatacc gaatggattg atagcttcaa agaatatgag
     1381 aaagtagagg aggaaaaagt aatccgtcct gaacttcatc ctgccacaaa ctcgttgagt
     1441 atgggggaag tggtacgtgc ggttagtgat gctactcacc atgaagctgt tttggtaaca
     1501 gatgtaggtc aaaatcagat gatatctgca cgctacttta aatatacgaa agaacgcagt
     1561 atcattactt ctggaggact tggaacaatg ggcttcgggc ttcccgcagc tattggggca
     1621 actttcggag caccggaacg taccgtatgc gtatttatgg gagatggcgg actgcaaatg
     1681 aatattcagg aactgggtac gattatggag cagaaggctc cggtgaagat tatctgcttg
     1741 aacaataatt acctcggaaa cgtacgtcag tggcaagcta tgtttttcaa ccgtcgctat
     1801 tcgtttaccc cgatgttgaa tccggattat atgaaagtgg cctcggctta tgatattcct
     1861 tccaagcgtg ttttcactcg tgaagaactg aaggaagcta ttgctgaaat gctggcaacg
     1921 gatggtccgt tcctgctcga agcttgcgtg gtggaagaag gcaatgtttt gccgatgact
     1981 cctccggggg ggtcggtaaa ccagatgttg ctggagtgct aggagaagtt gagaatggag
     2041 agttgagagt tcgcatttaa aaaattggag ttatgagtga taaaacgtta tatacaatca
     2101 ttgttcattc ggagaatata gctggattgc tgaatcaggt aactgctgta tttacccgtc
     2161 ggcaaataaa tattgagagt ctgaatgtat ctgcttcttc tattaaaggt gtacataagt
     2221 atacaataac agcctggact gataaggaca tcattgagaa ggtagtgaaa cagatcgaaa
     2281 agaagatcga cgtgattcag gcacattatt tcacagagga tgagatttat ttccacgaga
     2341 ttgcattata taaggtgtct actcctgctt ttcaggagaa tccggaagca tccaagctga
     2401 ttcgtagata caatgcacgt atagtggaag tcaatccggt attttctatt gtcgagaaaa
     2461 atggaatgag cgaagatata acttcgctct atggtgaact gaaggctttg aattgtgttt
     2521 tgcagtttgt tcgttcagga cgtgtagcga ttactaccag ctgttttgaa cgggtgaatg
     2581 agtttctcga tggacgggaa gctatgtata accaaagtaa aaaccaataa gaataatgag
     2641 tgaagaaaat agaataggga cttatcagtt tgtggcagaa ccgttccatg ttgacttcaa
     2701 cggacgtctg actatggggg tactgggaaa tcatctactg aattgtgcag gttttcacgc
     2761 caatgaccgt ggttttggta ttgcaacgct gaatgaggac aattatacat gggtgctttc
     2821 acgtctggct attgagttgg atgaaatgcc ttatcagtat gagaatttct cggttcagac
     2881 gtgggtggaa aatgtctacc gtttgtttac ggaccgtaat tttgctatta ttgataagga
     2941 tgggaagaag attggctacg cacgttccgt atgggcaatg attaatctta atacccgcaa
     3001 gcctgccgac ttgttgactt tgcatggggg aagtatcgta aactatgtct gtgatgagcc
     3061 ttgtccgatt gaaaagcctt cacgtatcaa agtgacaagc gatcagtcga tagctaccct
     3121 gacggcaaag tacagtgata tagatatcaa tggtcatgta aacagcatcc gttacatcga
     3181 acatatcctt gatttgttcc cgattgaatt gtataagacc aaacgtatcc gtcgttttga
     3241 aatggcgtat gtggcggaaa gctattttgg tgatgaactc tctttcttct gcgatgaagt
     3301 gaatgcaaac gagtttcacg tagaagtgaa gaagaatggc aacgaagttg tttgccgctc
     3361 gaaagtgata tttgaataaa tgtgagaata taaaatcaat taataacaga tggcgtaagt
     3421 catcaaaaac taaaaacaaa aagaaaat
//
