LOCUS       gnlProkkaJMKKPDAJ_149  13922 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JMKKPDAJ_149.
ACCESSION   gnlProkkaJMKKPDAJ_149
VERSION     gnlProkkaJMKKPDAJ_149
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 05:24:54
            Original ID  :: gnl|Prokka|JMKKPDAJ_149
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13922
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13922
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3571:3922]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3572..3922
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..13922
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13922
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             190..306
                     /locus_tag="ctg149_1"
                     /transl_table=11
                     /translation="MRNTLKYYENKVAFEPKYGRTYEKYRFEKVFLIRYLFD"
     CDS             581..2092
                     /locus_tag="ctg149_2"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPALTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSEDGIEEMET
                     NYEMLEIEQIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCQTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
     CDS             2165..3232
                     /locus_tag="ctg149_3"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELASVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSAGKKAAPAPAVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEEKTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKIPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             3269..3553
                     /locus_tag="ctg149_4"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(3572..3922)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg149_5"
                     /sec_met_domain="PqqD_RRE (E-value: 1.1e-11, bitscore:
                     34.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 4.1e-18, bitscore: 55.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVV"
     CDS             complement(4020..5408)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4.1e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg149_6"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMTIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             complement(5657..6052)
                     /locus_tag="ctg149_7"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             complement(6059..6832)
                     /locus_tag="ctg149_8"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSYLLEETPATEQSAEETPKLKGYELIDDFIEK
                     SESDSPLCKKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             complement(6838..7365)
                     /locus_tag="ctg149_9"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             complement(7352..8593)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 390.2; E-value:
                     2.3e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg149_10"
                     /transl_table=11
                     /translation="MTKAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMSTQARLLRVLESGEFMKVGSSKVQKTDVRVVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             complement(8603..9697)
                     /locus_tag="ctg149_11"
                     /transl_table=11
                     /translation="MEDNKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDIQANFSIVNSATEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGDKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEVIIPAMKEMEEKGILCYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPVVRTSPAHGTAYDIAGKGVACEDSFRQAIYVAIDVFRNRQREKVARAN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             complement(9702..10742)
                     /locus_tag="ctg149_12"
                     /transl_table=11
                     /translation="MKKYSFILCIALVAFVVASCGLKGNHTSSGRAYELLVVVDHGVWD
                     RAAGRALHDALDADMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIIIVDIQDIYTKASF
                     KYAKDVYANPQMILTIQAPNEEEFEKFVEENKKTIVDFFTRAEMNRQITFLEGKHSNFI
                     SQKVDSLFGCDIWVDAELANSKTGDDFFWASTNTGTADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGFKEGVYMSTDSLLTDVRPINVQNSYTMEARGLWRMKGDFMGGPYV
                     SHTRLDEKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPNEVQQKQIPLGEASKE
                     AEQTNK"
     CDS             complement(10761..11771)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg149_13"
                     /sec_met_domain="PF04055 (E-value: 2e-18, bitscore: 57.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLVELQSLTKRLDMPGFAAKQIASWLYEKKVASIDDMTNLSLKH
                     RELLKQNYEVGAEAPVDEMRSVDGTVKYLYKVGENHFVESVYIPDDDRATLCVSSQVGC
                     KMNCKFCMTGKQGYTANLTASQIINQIHSLPERDKLTNVVMMGMGEPLDNLDEVLKALE
                     LLTATYGYAWSPKRITLSTVGLRKGLQRFIEENDCHLAISLHSPLTVQRAELMPAEKAF
                     SITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCRVNLIRFHAI
                     PGVDLEGADMDTMTRFRDYLTSHGLFTTIRSSRGEDIFAACGMLSTAKQEKNNES"
ORIGIN
        1 cataatggat taagattgta atgaagacac aaaggtagga aggaaaagaa gggaaacaaa
       61 cacgcacgtg accgaatgct tacagcatct tcaagcaaaa agccactatt ttatctaaat
      121 agtagcttca tttcctgata aaaataaggc aggctgaaag aaaaaaggaa gaacaaatgg
      181 cttttgacta tgagaaatac cctgaaatac tatgagaata aggtggcttt tgagccaaaa
      241 tatgggagaa cttatgagaa ataccgtttc gaaaaagtgt ttctcataag atatctattt
      301 gattagcttt cgtttatcga aaaacaatga gaatatgaga aatgaaatga agaaatcttt
      361 ttcaggagaa ataaaagtaa gttcataatg gtgctgcatt gaattatttt ttggcggagt
      421 tattctaaca cttaatagtt caaaagcaga tatttctctg acccaaagat agaactaatg
      481 atgaattaaa agttgcaatt atggttttct tcccacaaca aacggaaaaa gtcagaagaa
      541 tcatgtacat ttgtaatccg aaaactaaaa gaacatcgca atgaaaatat ttccaagcag
      601 cagtatcaag aaattggacg cttataccat tgagaacgaa cctattgcat caatcgatct
      661 gatggaacgt gcagcaaccg tattaacaaa agccatcaca gacagatgga atacggaaac
      721 gccggtcact atctttgccg gaccggggaa taatggcgga gacgctctcg ccgtagcccg
      781 catgatggct gaaaaaggat ataaaatcga ggtatttctc ttcaacacga aaggagaact
      841 ttcacccgac tgccagacca ataaagaact ggtagaaatg atggaagaag taaaattcca
      901 cgagatcagt acccaattcg tacctcccgc cctgacgccc gaccatctgg taatcgacgg
      961 attattcggt tcaggcctga acaaaccgtt gagcggcgga ttcgctgccg tagtgaaata
     1021 catcaattcc tcccctgcca tggtagtagc catcgacatt ccttccggac tgatgggaga
     1081 agaaaacaca ttcaacgtaa aagctaatat tatccgtgcc gacgtaactt tcagtcttca
     1141 actgccgaag ctcgcctttc ttttcgcaga gaacacggaa tttgtcggag aatgggaagt
     1201 gctggatatc caattgagcg aagacggtat tgaagaaatg gagactaact acgaaatgtt
     1261 ggaaatagag caaatccgtt cactcatcaa gccacgcaaa cagtttgccc acaagggaaa
     1321 cttcggccat gcactattga ttgccggttc aaaaggaatg gcaggagcct ctgttctcgc
     1381 tgcccgcgcc tgcctccgtt cgggagtagg attactgact gttcatgcac caatgtgcaa
     1441 caacgacatc ttgcaaacct ccatacccga agcaatcgta gaaaccgaca tcaacgaaac
     1501 ctgttttgcc gtacctaccg acacggacga ctatcaagca gtcggcatcg gtccgggact
     1561 gggacgaaac gaggaaacgg aagctgcctt gttggaacaa ctggaacact gccagactcc
     1621 tgttgtggtg gatgccgacg cacttaatat ccttgccaac caccgccatg cccttaccca
     1681 cctgccgaag ggttccatcc tcaccccgca tccgaaagaa ctggaacgtc tgaccggcaa
     1741 atgccaggac tcttacgaac gtctgatgaa ggcttgcgaa ctggcccgtg ccgcccatgt
     1801 tcacattatt ttaaaaggag cctactccgc cattatcacc cccgaaggta aatgtttctt
     1861 caacccaacc ggaaatccgg gaatggcaac cggaggtagc ggtgacgtac tgaccggagt
     1921 aatcctggca ctgcttgccc aaggttaccc caccgaggaa gccgctaaaa tcggcactta
     1981 cattcacgga ctggcgggcg atgtcgctca aaagaagcaa ggaatgatcg gaatgatcgc
     2041 aagcgatatt atcacctgtc tgccgacagc atggcgactt gtaagcgaat aaaagttaag
     2101 aacttaccct tttttcaata acttcattaa ctttgttttc aaaaccagtt aaaaagaacc
     2161 gaatatgaaa aagttgatta tagcagcagg actacttatg acaacgtccg cctatgcaca
     2221 aaccgaagta ctgacggggg ttacccgagg aaaagactat ggagtggttt acagtcttcc
     2281 caaaacccaa atagaacttg aaataaaagc caacaaagtc aactatactc ccggagaatt
     2341 cagcaaatat gctgatcgtt acctgcgact gaccaacgtc tccgccgacc ctgaagagta
     2401 ttgggaacta gctagcgtaa aagtgaaatc cgtaggtgtg cccaacagcg aaactacgta
     2461 tttcgtaaaa ttgaaggata agacagtagc accgctcatg gaactgacag aggatggcat
     2521 tgtgaaaacg atcaatgttc cttacagcaa tagcagtgca ggcaaaaaag ctgctcccgc
     2581 ccccgcagtc ctccaaaaga aagcgaatcc tcgcgaattc ctgaccgaag agattctgat
     2641 ggctagttct accgccaaga tggccgagct ggtggctaaa gaaatctata atatccgcga
     2701 aagcaaaaat gccttattgc gcggacaagc tgataatatg ccttcagatg gggcacagct
     2761 taaaattatg cttgacaatc tgaatgcaca ggaagaagcc atgacacaaa tgttctccgg
     2821 cacctgcaac aaagaagaga aaacattcac tgtccgcctt acccctgaca aggaattcaa
     2881 caatgaagtt gctttccgct tctcgaagaa gttaggtgta gttgccaaca atgatttggc
     2941 aggaactccg ttttatatca gtctgaaaga cctgaaatcg gtcaagatac cacaggaaga
     3001 cggtaagaag aagaaagatt tggatggaat cgcctacaac gtacccggac aagctatggt
     3061 tacactgacc gacggcaaaa agaaacttta cgaaggtgaa cttcctatta ctcaatttgg
     3121 tgtgatagaa tatctggctc cggttttgtt caacaagaat tctaccatca aagtttattt
     3181 tgatccgaat acgggaggat tgctcaaagt ggacagagaa gaagggaaat agaaaaacga
     3241 ggaagtgaac ttctaaaaaa caaagaatat ggttggtgaa ggacatgcat tcgacatgat
     3301 acgccgaata aaagagggac gggaagcttc ccgcctacgt cgtgaacgtg ctaacgataa
     3361 gttgaagcat ctaaaccgtg caaacgaacc ttatccacta cccaacacca cccccgaaga
     3421 aatggaacgt atcatccacg actcggagaa aaagaaagag aaagacagca attattttgt
     3481 ttggggaacg cttattatca tgggggtcct gatagcaatt gccgtcatac tttgggctgt
     3541 atttatcaaa taaataataa taagttccta tttatacgac tggtatcacc agttttataa
     3601 atccatcttt ctgcatttga gaaagataag ccgatacacg cgactcgtag ccctcttcat
     3661 tttgaaagtg gtctgcgagt ttttctataa tctcacgaac attgcgtttt ccatctatca
     3721 gttcccatac agccgtaccg tgttcttcca atttcacatg aagttctttc gacattcctt
     3781 tcggcacaag gaagcgttgc atccacggat atttaaaacg gggaaaggag agcacaattg
     3841 tctccccttc cctttctgct gtaatatgtt cactgcgaca gggaatgacc tctaacaggt
     3901 tgattttctc tttggcagcc atacttctta ttttttattt cagagtattt atactgatac
     3961 tcttctgttt acaccttgat acaaaattcc tttgttactt taggtattga atttcccagt
     4021 tacttttgga tattcgcctc ttccaaaccg tatcccttct tcttgttctc tgccttcaac
     4081 atcaaagcca caatcagagc aagcacacca aaaagagcaa aaatagtcat cggcaacgtg
     4141 tagtcataag tctgtgcacc gtctactacc ggacctttgc aataagtatt caacacccat
     4201 ccgatcaaca aaggaacacc catcaatccc cagttctgta cccagaaaat caatgcgtat
     4261 gctgtaccca actgtttttc cggaataatc ttcggaacag acggccacat agctgaaggc
     4321 accaacgaga aggcaaatcc caatataatc atgataatag tagcaaacca ccatatattc
     4381 agtataggca gagcgaacat cgtatgcaca aaaataagca tcactgatcc gattatcatc
     4441 aacgtagctc ccttaccgat acggtcataa agcgagccga acaacggagt caggataatc
     4501 gcaccaatcg gcaacaatcc gggaatcgtt cccgccaact tcggatctac attatacttc
     4561 tgcaccatca agtcggcagc atacttgata aaggggaata cagccgagta gaacaataca
     4621 catagtaatg caatcagcca gaatccctta ttcgtaatga tatacacaat atctttcata
     4681 cggaacggct cttccggctc caatccctct gcatccaaag aagcatccaa cttcttatca
     4741 tagaaagtat aaaggaagaa agcaatcgta cccacgcaca acataatcag acaaaacaaa
     4801 atcggagcag gaatattggt atggaatgtg ccactctcat ccgtagatcc gaaaaagtcg
     4861 gccaaaggaa ccgtgagcac cattgccaga gttgttccga tacgtgccgt agccatttca
     4921 agtcccatag ccaatgccat ttccttaccc ttgaaccatt ttacgataat tttggaaact
     4981 gtgataccgg caatttccac acctacaccg aagatagcat accccaatgc ggccagggtt
     5041 acctgtgttt tgaatccaaa gagcatggca ccttccggaa aagtagtaga aatcgcatag
     5101 tatttcaatc cacaaccaaa caccatcaat aagcaagccc ccattccggt gaaacgaact
     5161 cccatcttat ccaaaatgat accaccgaaa atcagcatca ataggaatac attaaaccac
     5221 ccgtaagcgc ttgtgaagaa accataatca agactgtccc atagtagttc tttctcaagc
     5281 atgggtttta gaggagacat tacgtcggtg aggaaatagc cgcatagcat agtaaatgcg
     5341 accaatgcta gaacactcca tcggagtacg gcggagtcat tcaatttctg tttcaaatgt
     5401 tctgtcattg ttatatttaa aaaagtagtt aataatcttc atacgaccaa caaaggtagt
     5461 taaatctcgt ttgtttctat caaaaagaga ttgtttttac aagaaaaagt taagtgcgga
     5521 ttacactgac cacgcggaag attgaaaatc cgtgtaatct gcgtaatccg cacttaaata
     5581 tcaaagaagt gcagcatccg tctgcacctt cccattaatg gttttacccc aaagtcttac
     5641 ctgacaacgg agtgaattac tctgctgcag gagcaggagt ttcagtagca ggtgccggag
     5701 tttctgtagc aggtgcattg gtagcaggag cttcagtttg cggcgcagcc gtacctgcgg
     5761 gtaagttata cgggttagtc tgttgttctt tctgtgcctg ttccaacact gcgtctttag
     5821 caacagcaga gcgaggaact acataagcag tagcaatgct cattaccacc atgaagatag
     5881 ctaagcccca tgttgctttt tccagaaaat ctgtagtctt gcgcacgccc atgatggcgt
     5941 tagatgaaga gaaaccagaa gcaagtccgc ctccttttga gttctgaatc agcacgatga
     6001 aacacatcaa caaggctgca ataaccatta agataacgaa taataagtac atttttagtt
     6061 attttgaatt agcgttaata atcaatttct ccaaaaatct gatttggtct gcaaagtaag
     6121 catttttttt tggatatttc aagcttaatt ttttaattat ttcaagagct tttgaatatc
     6181 gttgctgttt aacatagatt tttgccaaag tttccgtaaa acagctgtca tcttcctctt
     6241 cttccttcat cgtttcttct tcggtaagtt cgtccgaaga ggttggcgaa gatggcattt
     6301 cttctcttaa aggtttcttg cagaggggag agtcgctctc gctcttttct ataaagtcgt
     6361 caatcagttc gtagcctttg agtttgggcg tttcttcggc cgactgttcc gtggccggag
     6421 tctcctccaa aagataagag gtgtaatcca tcgaatagtc gaagctggtg cgggcagtca
     6481 cctcttcggg tactgtggac aagaaagcgt cgatcaatgc taatgtgcgg tctacggacg
     6541 gttcgtcttt cagcacctcc gtgagaggta ctcccttttt ccgtgcctgc acatcatagc
     6601 ggtcaccttc aatcaaccgg aacaactgcc gtctgtctgc aatgtaaaga actgctttcc
     6661 gcagttctcc accgaaacta atatcatgga gaatatacag attcttcaga tacagcagac
     6721 gaagtgactg aaaatacgga tacctcgcaa gaagattgcg cagttcgtac aaagtatccc
     6781 tattcagcgt ctcgggatgc tgaatccatt gttgaaagtt aacagaagtc atttatatta
     6841 ccagtttgct acagttgcat taaaaatttg gtcggtgatc tctttagaca tttcagcaat
     6901 caatccgtcc tgtacggcag tcagcaactg gctagagtcg taggtacgga acgcagaaaa
     6961 ctgttgttca aagtcttcgg catgattggt gttgttgaca aaacgtacat tgacggtaat
     7021 agtcaacttc gtctccgaag agtaaccgtc ggcagatact gcctggttgt actgattgta
     7081 tcctgtgatt tctccgtcaa tctgcaagtc cgcattctga ttcggcttga gcagttgcag
     7141 acgggtctgc cggatgaaga tatctttcag gtcctcattg aatttggttg ctaacggagc
     7201 atatacatac tccgacttga tcgggaagtc ggctatcgaa atggtcttta ccttatcata
     7261 attgatagac gatccgttaa acttatagga aacagtgcac gcaatgacta ccaacggcaa
     7321 gccgaacagt aacaaagggc gtattatttt cttaatccaa ttcatattct tttatttttc
     7381 tataaagtgt acgctcggaa atattcaagt ccttggccgc actcttccgc tttccatgat
     7441 gcctctcaag tgccttgcgt atcatttctt tctccacttc atccagtgac aaaggagatt
     7501 cttctacata ttcttccgtg tcttgtatgt catcatcatc cttgcaaacc gtaggctgca
     7561 tggtgtgaat aatagcaggt accgaaggtt gatgcgccgt cactaccgga gtagtaacca
     7621 ccgttcccat ttgtcctacc tgccccacct gtccggcacg ttccgccatc aggttgtgca
     7681 ccatcttctt cagctccgcc acttcctggc gcatatcgaa cagaacggaa taaagaatct
     7741 cccgttcgct ctcaaagcct ttactctcac gcgttcccat caacgcggga agacgttgcg
     7801 tattttgtgc aggaagataa ttctgcaaga tagcagcaga gatctccctg ttggtttcaa
     7861 tgatagatat ttgctcggtg atgttcttca actggcgcac gtttccgggc cacgggtaag
     7921 ccaacaactc tttcttcgca tcctccgtca actgaatagc aggcatccgg tatttctctg
     7981 caaagtctgc ggaaaactta cggaacaaca aaagtacatc gtcaccacgt tcacgcaaag
     8041 gcggtatttg gataggcacc gtattcaacc ggtaatataa atcttcacgg aaacgtcctt
     8101 ctgcaatcgc ttgtgtcaga ttgacattgg tagccgccac cacacgcaca tccgtttttt
     8161 gtactttgga cgaacctact ttcataaact cgccactctc cagtacacgg agcaaacgtg
     8221 cctgggtaga catcggcaac tcccctactt catcaagaaa aatagtaccg ccgtcggctt
     8281 cgccaaagta ccctttccgt tcgccaatcg caccggtaaa cgcacctttc tcatgtccga
     8341 acagttcgga atcaatcgta ccttccggaa tagcgccaca gttgacagca atatactgcc
     8401 cgtgcttcct ccggctatat tgatgaataa tctgcggaaa actttctttt ccgactccac
     8461 tttctccggt aatcagcaca gacaaatcgg taggagctac ctgaatggca acatctatgg
     8521 cgcgcgacaa tgcttcagta tttccaataa taccgaaacg ctgtttcact tgttgtatct
     8581 ctgctttcgt catcactcgt ttttaatctt cgtctactgt atccagcttc agtttatcac
     8641 tatcgtcacg tttctcgtaa tactgtttac gcaacggatt ggcacgagcc actttttccc
     8701 gctgacgatt acggaacacg tcgatggcaa catagattgc ctgacggaaa gaatcttcac
     8761 aagccactcc cttgcctgca atatcgtatg ccgttccatg agccggagaa gtacgtacta
     8821 ccggcagacc tgccgtatag ttcaccccgt cttccatagc caaggcctta aacggagcca
     8881 gcccttgatc gtgatacatc gccaggatac cgtcaaaatg agtataattg cccgaaccca
     8941 taaagccgtc ggccgcataa ggaccgtagc aaaggattcc tttttcttcc atttctttca
     9001 tggcagggat aatcacttcc tgctcttcca ttcccaacag accaccgtct ccggcatgag
     9061 gattgagaga gagcaccgca atacgcggag cgccgatacc gaaatcctgt ttcaggcaac
     9121 gatggaatat catcagtttc tcctgaatca gttctttggt aatcgtagtc gcgatctctc
     9181 tgacagggat atgtgtcgtc accaaagcca cccggaagtc attcttcatc aaaatcatca
     9241 atgacttatc accattgccc agacgttctt cgatatattc cgtatgtccg gggaaggaga
     9301 actcttccga ctgaatcgta tgtttgttga tcggagctgt tacgataacg tctatcaacc
     9361 cttcgcgata ttcttcgatg gcacgttcca aagcccccag cgcagcttta ccggcttcgg
     9421 ggtcgggttt ggaaaattcc actttcacct catcatccgt acagttcacc acgctcaaac
     9481 ggttgtaccc cgcttcggta gcagagttga caatgctgaa attggcctgt atatccagcg
     9541 ctttgcgatg ataagccgct actttcggtg agccataaat gatcggagta catagttcca
     9601 acattgtagg gtcggaaaat gtcttaagaa tcacctcata gcccaccccg ttaatatctc
     9661 cttgggtgat acctatcctt atcttgttat cttccatgtt tttatttatt agtttgttcc
     9721 gcttccttag atgcttctcc caatggaatc tgcttctgct gaacttcatt cggaagtttc
     9781 agtgtataca gagatgcttc catctggcgt accaggttgc gtttcatttt atcaggtgaa
     9841 taaacaaata tttctgcagt aataattcgt tggtttttct cgtccagacg agtatgagat
     9901 acatacggac cacccataaa gtcgcccttc atacgccaca ggccacgtgc ttccattgtg
     9961 tagctgttct gtacattgat cggacggaca tcggtcagca aactatcggt cgacatataa
    10021 acgccctcct tgaatccggg gatattggct ttcatcacgg agtcacgttt gtgcacaaaa
    10081 tattctttgg taaacgtatc cttgtcagtg tacggataag agtacatcac aaagttacgg
    10141 tcggcagtac ctgtgttggt agaagcccag aagaaatcat ccccggtctt tgaattagcc
    10201 agttcggcat ccacccagat gtcgcatccg aacaaactgt ccactttctg cgaaatgaaa
    10261 ttactgtgtt tcccttccag gaatgtaatc tgacggttca tttccgcacg ggtaaagaag
    10321 tcgacaatcg tctttttgtt ctcttccaca aacttctcaa actcttcttc gttcggagcc
    10381 tggatagtca atatcatctg cggattggca tacacgtcct tcgcatattt gaacgaggct
    10441 ttcgtatata tatcctgtat atctacaata ataatgttac gtatcaactt cagcgtagaa
    10501 tcataatctt tcggtgaagt atacataatc cggaaagaag gttccgactg cggcaaaccg
    10561 ggcatatcag catcgagcgc atcatgtaaa gcccttccgg cagcacgatc ccaaacaccg
    10621 tgatctacta caaccaaaag ctcgtaagca cgaccactag aggtgtgatt tcctttcaga
    10681 ccacaagatg caacgacaaa ggctaccaaa gcgatgcata aaataaaaga gtactttttc
    10741 atgatgttcg gttttatata ttaactttca ttatttttct cctgtttcgc tgtcgacagc
    10801 ataccgcaag cggcaaaaat atcttcgccc ctggatgaac ggatagtggt gaaaagtccg
    10861 tgtgacgtca gataatcacg aaaacgggtc atcgtatcca tgtccgcccc ctcgaggtct
    10921 acccccggta tggcatgaaa acgaatcaga ttcaccctgc aatccagccc gcgaagaagt
    10981 ttcagcaact ctttggcata gacctgcgaa tcattgagcc ctttaaaaac aatatattca
    11041 aacgaaagtc gacgttgttt actaaaatca tagtttttta acagttccac catttcggtg
    11101 attgaaaacg ccttttccgc cggcattaat tcagcacgct gaacggtcag cggagagtga
    11161 aggctgatgg caaggtggca gtcattttct tcgataaaac gctgcaatcc tttccgtagc
    11221 ccgacagtag aaagcgtgat acgcttcgga ctccatgcgt aaccgtaggt agcggtcagt
    11281 agttccaatg ctttcaatac ctcatccagg ttatcgagcg gctcgcccat tcccatcatt
    11341 acgacattag tcagtttgtc ccgttccggc agcgaatgaa tctggtttat gatctggctg
    11401 gcggtcaggt tagccgtata cccctgtttg ccggtcatac agaacttaca gttcatcttg
    11461 caacctactt gtgacgacac gcacaacgtt gcccggtcat catccggtat ataaaccgac
    11521 tctacaaaat ggttctcacc cactttataa agatacttca ccgtaccatc tacagagcgc
    11581 atttcatcta ccggagcttc cgctcccacc tcatagttct gcttgagcaa ctcccggtgt
    11641 ttcaatgaca aattagtcat atcatcaatc gaggctacct tcttttcgta aagccaggat
    11701 gcaatctgct tggcagcaaa gccgggcata tccagtcttt ttgtcaatga ttgaagctct
    11761 acaagagtca ttcctaaaag gggatattta gacattcttc tttctgttga tagtttatat
    11821 ctgcaaatgt aaggaaataa agtcgatttc cgtatagcag gaatgtaaaa gttaacaaaa
    11881 aagggaagta tgcctccgtt atgattcaac cacgctgata tattgaagta gcttttgcgc
    11941 catttcagaa tcctcgccat tctttttcac ttcatgaccg tacgcctcac ggaaacaagc
    12001 cagcgcctct tcccgttcat tacaaaagct gtgcaaaacc cctaagttct gacaagccag
    12061 aatcgtatct tcttcctccc atcccaaata cttctttcgc agttcgaact ctctgaagaa
    12121 agcctctttc gccattggat aattctccaa cttcacataa gcctgtgctt tgtaataata
    12181 taccagacag gaagcattag ggtcagcatc atcgtgaata tccaaagacg ttgcaatacg
    12241 aatcacgtta tcatagtctt tattcatgta atactgctgc ataatatcac atctcaatgc
    12301 ctcgtagcgg acagtcagtt ccgccagacg cggtttttcg ctgaaacaca tttcatgcag
    12361 aagagactca cggaagaata aagtagacgc ctgctcatcg ccacgttcat tcatcatccg
    12421 tttgaattcc ctgcatagat aatacaactg tttatgacaa gcgacgatct gttttttatt
    12481 atctatctgt atagcaatgt ccaacgcctg attcatcagc atccatgctt catcgtatcg
    12541 tttgatataa taaagacatt taccctgcat acgcaaacat ttagccactc caccggacag
    12601 tctgccattc aacgactcgt gcatttcagc tactttccgg aatttctcgg cagcactctc
    12661 ttcctcatcc ttatagtaat cacaataagc cagatattcg gaaagttcaa tgacttctgc
    12721 ctgactcttc tcgtcagcag aagccgcatg ataatcaagc gccctattca aatagatcgc
    12781 cgcttcattg tattgctcat tgtagtaata tgccaaagct agatttcgac aggtgttggc
    12841 aatctccagt tccggagtcg gtactatgtt ttcctgcatc accaatgctt tcaggaaaca
    12901 gtcgcatgcc gtttcgtatt cttcattacg ggcataccga catccctcat tcatcttcaa
    12961 taccgacttg gcaatgagtg gcatggcagc accttccata ctcttctcac tcacagcagc
    13021 tgccgccttc gtcagatgga aagaactgct caagaaagta gccatatcat tagcaatgac
    13081 aggaattaaa aaagaatcga tctcatcaaa gtccaattcg gcatagactt caggcgtaac
    13141 ttcaggattg tcgttcatga tcgccttcca gctatcttcc aacagaaaac gattcgtgcg
    13201 atacagaatc tcgaaaatct ccacatcaca aatccaatcc ttcaatatat cccattcttg
    13261 catcttatag cattgatagg taatctccac tttatagcga tacgaatcat ggtagcagaa
    13321 ctgtttcatg cgatagttat aatcggcaaa agtcaacgga tgggaaagga tttcttcctc
    13381 atccagcaga gcggaaataa tttcatggcg actatcatct atacattcgt catcttgagc
    13441 gaaatagcgt tcgatcgcct ctaccatttg tgtatcacca atgcaatatc gtcctccttt
    13501 gttggtgagc cagctgctca tttccactct caactgcgac caaagtatct gattaatgtc
    13561 tgccatgctc ttcacttcat cttcggtaaa tccttctaaa gtaagtgaaa gcatcagaag
    13621 cgttcttcca atctcttcgg aaccataatc agccgacaaa cgccgtagca cactgtcata
    13681 gaattgccca acctcattga gccggcaata tccacgcata tattcattga gagcatcgta
    13741 ctgaccgaac gaaaccagct cgttgagcaa tacacttaaa cagcgcggtt gttcagccag
    13801 cacccacgaa gcaagaatat cttcctgctg tgcagacaaa gccttggagt aagtagacaa
    13861 atattgcttt gagaacgact tggcatccgc ctgtgaaaag ccattcaact ggaaatgagc
    13921 gt
//
