LOCUS       gnlProkkaCNCIGDAG_515   3248 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CNCIGDAG_515.
ACCESSION   gnlProkkaCNCIGDAG_515
VERSION     gnlProkkaCNCIGDAG_515
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 09:45:26
            Original ID  :: gnl|Prokka|CNCIGDAG_515
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3248
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3248
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[50:1274]"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      51..1274
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     cand_cluster    1..3248
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /kind="single"
                     /product="arylpolyene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3248
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="arylpolyene"
                     /region_number="1"
                     /rules="(APE_KS1 or APE_KS2)"
                     /tool="antismash"
     CDS             51..1274
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (65-405). E-value:
                     1.8e-53. Score: 173.8. Matches aSDomain:
                     nrpspksdomains_ctg515_1_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 296.3; E-value:
                     6.6e-90)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg515_1"
                     /sec_met_domain="APE_KS1 (E-value: 6e-160, bitscore: 520.4,
                     seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRVVITGMGIYSCIGKNLDEVKDSLYNGKSGIGIDPVRKELGYF
                     SALTGILERPDLKKLLDRRKRLCLPEQGEYAYLATLEAFRNAGIDEAFLEANEVGILYG
                     NDSSAAPVINAVDIIREKKNTALVGSGSIFQSMNSTVTMNLSVIFKLRGVNFTIAGACA
                     SGSHAIGMGYLLIKSGLQDCILCGGAQEVNPYAVGSFDGLSAFSTQEAEPEKASKPFDK
                     RRDGLIPSGGAASLVLESYESAVKRGAPILAEVIGYGFSSNGDHISVPNVDGPKRSLQM
                     AIKDAGIALEQISYINAHATSTPVGDLNEAKAIAEVFEGHHPYVTSTKSMTGHEMWMAG
                     ASEVIYSTLMMNNGFIAPNLNFEEPDEASAQLNIPTQRVNLEFDTFLSNSFGFGGTNST
                     LIIRQIKE"
     aSDomain        246..1265
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg515_1_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.80E-53"
                     /label="ctg515_1_PKS_KS.1"
                     /locus_tag="ctg515_1"
                     /protein_end="405"
                     /protein_start="65"
                     /score="173.8"
                     /tool="antismash"
                     /translation="RLCLPEQGEYAYLATLEAFRNAGIDEAFLEANEVGILYGNDSSAA
                     PVINAVDIIREKKNTALVGSGSIFQSMNSTVTMNLSVIFKLRGVNFTIAGACASGSHAI
                     GMGYLLIKSGLQDCILCGGAQEVNPYAVGSFDGLSAFSTQEAEPEKASKPFDKRRDGLI
                     PSGGAASLVLESYESAVKRGAPILAEVIGYGFSSNGDHISVPNVDGPKRSLQMAIKDAG
                     IALEQISYINAHATSTPVGDLNEAKAIAEVFEGHHPYVTSTKSMTGHEMWMAGASEVIY
                     STLMMNNGFIAPNLNFEEPDEASAQLNIPTQRVNLEFDTFLSNSFGFGGTNSTLIIRQI
                     "
     CDS             1296..1547
                     /NRPS_PKS="Domain: PP-binding (7-75). E-value: 2.3e-14.
                     Score: 45.6. Matches aSDomain:
                     nrpspksdomains_ctg515_2_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg515_2"
                     /sec_met_domain="PP-binding (E-value: 1.7e-15, bitscore:
                     45.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNEEIIEKIRTTLAEEFEVDIDVIQPDAPLMETLELDSLDLVDM
                     VVLVEKNFGFNVTGQDFADIKTFQDFYDLVITRMQEAK"
     aSDomain        1317..1520
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg515_2_PP-binding.1"
                     /evalue="2.30E-14"
                     /label="ctg515_2_PP-binding.1"
                     /locus_tag="ctg515_2"
                     /protein_end="75"
                     /protein_start="7"
                     /score="45.6"
                     /tool="antismash"
                     /translation="EKIRTTLAEEFEVDIDVIQPDAPLMETLELDSLDLVDMVVLVEKN
                     FGFNVTGQDFADIKTFQDFYDLV"
     CDS             1550..2467
                     /locus_tag="ctg515_3"
                     /transl_table=11
                     /translation="MSTWKGKTRGGTFGYLFFIYLIKYLGITAAYLFLSLVVLYFIPFA
                     PKATKSTWFYARNILKYNRIHSLKMLLLNYYRLGQILIDKVAIGNGKVNQYQFKFERYP
                     EFLQLLNSEQGVIMIGAHVGNWEIGVPFFDDYGKKINIVMYDAEHRRIKEILEKNGQDK
                     DFKIIPVNEDNLTHVFRITEALNKKEYVCFQGDRYLNKEKLLTGTLLEQKAPFPAGPFL
                     LGSRMKVPVVFYFAMREPGRTYRFHFIRTEPVIRTKEKKAEIALLEQYTAALDQILKRY
                     PEQWFNYYSFWETTSDGSPSKGLK"
     CDS             2486..3247
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 69.7; E-value:
                     4.4e-21)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg515_4"
                     /transl_table=11
                     /translation="MQQNQYDKEPLTAVEAQRLAQEIAFGPIVFQVSRLMLKFGIFQLL
                     ANERAGMTQEEISKACGLSSYATQVLLEASLTIGTVLQHENRYRLAKAGWFLLNDKMVR
                     VNMDFNHDVNYLGMFHLEEALTNGRPEGLKVFGEWSTIYEGLSSLPSQVQKSWFGFDHY
                     YSDCSFDEALAIVFARHPKTLLDVGGNTGRWATKCVSYDDAVEVTIMDLPQQLEMMRQQ
                     TKELPGAMRIHGYGANLLDPEVPFPTGFDAIW"
ORIGIN
        1 atcaacggag gactatatac ttaaaataaa agcatagaat agacaaaata atgaaaagag
       61 ttgttatcac gggaatggga atttactctt gcatcggcaa gaacctggat gaagtaaaag
      121 actcactata caatgggaaa tcggggattg gcatagatcc ggtacggaaa gagctgggct
      181 atttttctgc attaacgggc atattggaac gtcccgactt gaagaaacta ttagatcgtc
      241 gtaaacgtct ctgcctgccg gaacagggag aatatgctta tctcgctact ttggaggctt
      301 tccgcaacgc cggtattgac gaggcttttc tcgaagctaa tgaagtgggt atcttgtatg
      361 gcaatgatag tagtgccgcc cctgttatca acgcagtgga catcattcgt gaaaagaaaa
      421 atacagcgtt ggtaggttcc ggttctattt tccagtcgat gaattctacc gtgacaatga
      481 acctgtcggt tatcttcaag cttagaggag ttaacttcac cattgccgga gcctgcgcaa
      541 gtggttctca tgctattggc atgggttatc tgctcattaa atcaggattg caggattgta
      601 ttctttgcgg tggtgcacaa gaagtaaatc cttatgcggt cggcagtttc gacgggctaa
      661 gcgcattttc cacccaggaa gcagagcccg agaaagcctc caaacctttt gataaacgac
      721 gtgacggact gattccgagt ggaggagccg ccagtctggt attagagagc tatgaatcgg
      781 cagtaaaaag gggagctccc attttggccg aagttatcgg ttacggtttc tcttccaatg
      841 gagatcatat ctccgtaccg aatgtggacg gtccgaaacg ttctcttcag atggccatca
      901 aagatgcggg tattgcactc gaacaaatca gttatatcaa tgcacacgcc acttccactc
      961 cggtaggcga cctgaacgaa gcgaaagcca ttgcggaagt atttgaagga catcacccgt
     1021 atgtcacttc cacgaagtct atgaccggac atgaaatgtg gatggcaggt gccagtgaag
     1081 tgatttactc caccctcatg atgaacaacg gtttcatcgc tcccaacctc aatttcgagg
     1141 aaccggatga ggcttccgca cagttgaata tacctaccca acgggtaaat ctggaatttg
     1201 acacgttcct ttccaattcg tttggattcg gaggaaccaa ttccaccctg attatacgcc
     1261 aaatcaaaga ataaattact aaagaaaaca gatatatgac aaatgaagaa atcattgaga
     1321 aaataagaac aactctggca gaagagtttg aagtagacat cgacgtcatc cagccggatg
     1381 cgccgttaat ggaaactctt gaactggaca gtctcgactt ggtcgacatg gtggtactgg
     1441 tagaaaagaa tttcggtttc aatgtaaccg gacaagactt tgcagatatc aaaaccttcc
     1501 aggacttcta cgatctcgtt atcacccgta tgcaggaagc caagtaaata tgtcgacgtg
     1561 gaaaggcaaa acccggggag gaacgttcgg atacttattc tttatttacc tgattaagta
     1621 tctgggcatc actgccgctt atctttttct aagcctggta gtgctctact tcataccgtt
     1681 tgctccgaaa gcaaccaaaa gcacctggtt ttacgcccgt aacattctga aatacaatag
     1741 gatacattct ttgaaaatgt tactactcaa ctattaccga ttaggacaaa tcctgattga
     1801 caaggtagcc atcggtaatg gaaaagtaaa tcaatatcag ttcaaattcg agcggtatcc
     1861 ggagtttctg caactgctga acagtgaaca gggagtgatt atgattggcg cccatgtggg
     1921 aaactgggaa ataggcgttc ctttcttcga cgattatgga aagaaaatca atatcgtgat
     1981 gtatgatgcc gaacatcgta gaatcaaaga gatattggag aaaaatggtc aggataagga
     2041 ttttaagatt atccccgtca acgaagataa cctgacacac gttttccgta ttaccgaggc
     2101 gttaaacaag aaagagtatg tatgcttcca gggcgaccgt tatctgaata aagagaaact
     2161 actgacagga acactcctgg aacagaaagc tcctttccct gccggtcctt tcctgcttgg
     2221 ttcgcgaatg aaagttccag tggtattcta ctttgccatg agagagccgg gcagaaccta
     2281 ccgttttcat tttataagga cggaaccagt catacgaacc aaagaaaaga aagcagagat
     2341 cgctctgctc gaacaatata cggccgcttt ggaccaaata ctgaagcgct atccggaaca
     2401 atggttcaac tattactcat tctgggaaac cacgagtgac ggttcgccct ccaaaggatt
     2461 gaaataaaga tataacaaaa taaagatgca acagaatcaa tatgataagg aaccgttgac
     2521 cgcggtagag gcacaacgcc tggcacaaga aatagctttc gggcccatcg tgtttcaggt
     2581 atcacgcctt atgctcaaat tcggtatttt ccagttacta gccaacgaac gcgcaggcat
     2641 gacacaagaa gaaatcagca aggcttgtgg cctgtcttct tatgcgacac aagtattgct
     2701 ggaagcctca ttaaccatcg gtaccgtatt gcagcacgaa aaccgttacc gccttgccaa
     2761 agccggatgg ttcctgctca acgacaagat ggtacgtgtc aatatggatt tcaaccacga
     2821 tgtcaactat ctgggaatgt tccatcttga agaggctctc accaacggac gtcccgaagg
     2881 gctgaaagta ttcggcgaat ggagcactat ctatgaaggg ctgtcaagct tgccctcaca
     2941 ggtacaaaag agctggttcg gtttcgatca ttattactcg gattgctcgt ttgacgaagc
     3001 tttggctatt gttttcgccc gtcatcccaa gactttactg gatgtgggag gtaataccgg
     3061 tcgatgggca accaagtgcg taagctatga cgacgcggtg gaagttacta ttatggacct
     3121 tccgcaacaa ttggagatga tgcgtcaaca aactaaagaa ctgcccggag caatgcgtat
     3181 ccacgggtat ggcgccaatc tgctcgatcc cgaagttcct ttcccgacag ggttcgatgc
     3241 tatctgga
//
