LOCUS       gnlProkkaCNCIGDAG_831  14703 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CNCIGDAG_831.
ACCESSION   gnlProkkaCNCIGDAG_831
VERSION     gnlProkkaCNCIGDAG_831
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 09:45:26
            Original ID  :: gnl|Prokka|CNCIGDAG_831
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14703
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14703
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[11852:14703]"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      11853..14703
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     cand_cluster    1..14703
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /kind="single"
                     /product="arylpolyene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14703
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="arylpolyene"
                     /region_number="1"
                     /rules="(APE_KS1 or APE_KS2)"
                     /tool="antismash"
     CDS             complement(2..400)
                     /locus_tag="ctg831_1"
                     /transl_table=11
                     /translation="MEKNPEIQFRSPEEIKCYQEERLTQTLTYLQAHSKFYQRMFEEHH
                     IDINQIKKIEDLQQIPVTTKTDLQLHNDDFICVDKEQIIDYVTTSGTLGDPVTFVLTSE
                     DLDRLSYNEYLSFTTTGCSKKDILQLMTT"
     CDS             complement(384..2120)
                     /locus_tag="ctg831_2"
                     /transl_table=11
                     /translation="MHKTIKKIFKYTSCVLLSLLVILIAGICYLYFSADMRTPKHEPSI
                     IMTKVSHADTTTMVPAEVLYNDTLDLRYYDGNFLRHSESGLWELFVKGDAFQRGEAIGK
                     LSSDLLHYQEKVFVDQIREIVPSDSYLKFLRFFIVLFNRHLGENVLEEYRDEIYGISLS
                     CTHEYDFIGTPYERQLNYHSAHDLGHAMQDYMLVGCSSFATWGTQSADSSLLIGRNFDF
                     YVGDAFAENKQVAFYTPDQGYKFASVGWPGMIGVLSGMNETGLTVTINAAKSAVPTGSA
                     TPISILTREILQYASTIDEAFAIAQKRKTFVSESILIGSSKDGKAAIIEKSPEKTVLFK
                     GKEADRLICTNHYQSEEFSKDERNMENIRTSDSPYRFARLKELINENLPIDASKAASIL
                     RNHKGLQDADLGLANEMAINQFIAHHSVIFQPEKRLMWVSTSPWQCGKYIAYDLNKIFN
                     DTINLQHEIYSSNLTIPADEFTETPEFQHLLTYKKLTPLLLKKIRKKEKIEEHILKTYE
                     ASNPSLYYVYEVMGDYYEAMQQPQQAIVYWQKALKKPIPKLQEKERIQQKIQKQSKDGK
                     ES"
     CDS             complement(2113..3603)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222:dehydrogenase (Score: 159.2; E-value: 3e-48)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg831_3"
                     /sec_met_domain="DAO (E-value: 2.4e-10, bitscore: 30.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKYDIIIIGSGLGGLECGAILSKEGFSVCVVEKNTQFGGCFQTY
                     RRKGHLFDTGIHYVGSLDEGQVMNQYFRYFGIMDKLKLKRLDDEAFDTIYYKGKTYDYA
                     MGYPQFIETICRSFPHEKENLKRYAEQLQTVGNLISVDHLKQGTLALEGMKYFCTSAAG
                     LIADITPDPTLQNVLAGSALLYGGLKDVSTFYQHAMINHSYIEGAYRFVDGSMQVSLEL
                     INVIRANGGTVLNNSEATRIIVENEKVQGVIINGEKRLESDFVISSMHPQRTLEILDKN
                     RSIKNAYISRIRSLENTYGIFTLYLVMKKKSTPYQNRNLYLHGDHKVWYDKQLYPGRTT
                     NCMISMQASSEDSQYASVISILTPMYMNELSAWKDTTPEHRGESYRSFKQEKTEQLLRF
                     IRSHGIDFSDNIEEIHTTTPLSYRDYTGTVDGSAYGIIKDYKCPQIGFVSTRSRLGNLF
                     LTGQNLNVHGALGVTLTSMLTCAEFVGQEYLAKKVGNA"
     CDS             complement(3596..4171)
                     /locus_tag="ctg831_4"
                     /transl_table=11
                     /translation="MERNYRLFNQLIPVQGQITDIGCGYGPLCYMLSLLSEDREILGID
                     YDEDKIALAQHGWLRNEHLQFRHGNALEYPLPESDVFILNDMLHYMSYEHQRTLLLKCA
                     DRLRSQGMIIIRDGNSANTSKHRLTRFTELLSTRIFNFNRTAGELHFTTETQLREIAVT
                     CGMNVEIIPNDKYTSNTIYIFRKPNEHE"
     CDS             complement(4212..7289)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035:MMPL domain-containing transport protein (Score:
                     45.6; E-value: 4.6e-14)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg831_5"
                     /transl_table=11
                     /translation="MTQFFIGLYDYFERHKILFYLSLISCVLLMGFFALQVRFEENITQ
                     FFPDTKDSQNTIKVFDNLKIKDKIIIMLSSADTCHRVEPDSLIEAAGRLQQTLTEKAGG
                     TLIKGIFAQVDQSLIGGATDFVYEHLPLFLTDTDYQRFDSLLTEKGIQAIMQKNYTNLL
                     SPAGIALRSYILRDPLGLGSEALKHLQDFQLEANYEIYDEHIFSKDGSTLLMFITPVFS
                     TGSTGKNDELIKILEEELQHVQGESPTIRAEYFGGPSVGVYNARQIKKDTILTSSLALL
                     IIIVFISLVFKRKRSIPLIITPVLFGGLFALFLIFFIKGSISAIAVGAGSAVMGIALSY
                     SIHMLAHQNHVSTVQQLIKEIAYPLTVGSFTTIGAFMGLIFTSSDLLRDFGLFASLALV
                     GTTLFCLIYLPHFLKGQADVKQGRVLRIIEKINAYSYEKNKWLVGGILLITIICLFTSQ
                     KVGFNNDMMSLNYEPQHLKQSEEKLMQLFDSDEKTVLFVSVGKDMNQATETYAITNQKL
                     STLKDQGLIKDYASASQFLISPQEQQLRLKRWKDYWTDEKQQQIRKQLETAATEYRFRP
                     GSFDPFYQWLNQPFGEYHYTAQEDDLSGKLLNEWQTSADSITMLISQIRISDQNKETVY
                     QNFSKTQDVVIFDRSYFANKWVSAINDDFYLILYISSFLIFFALWFSYGRIELTLMSFL
                     PMLVSWVIILGLMGILGIEFNIINIILSTFIFGIGDDFSIFIMDGLQNKYRTGQKVLNS
                     HKTAIFFSAFTTVVGMGALVFAKHPALQSISLISILGMIAVVLVAYTIQPLIFRFFIAG
                     PASKGLPPYTLIGLIRTVLLFLLFFIGCIFLRVLIAVLYLVPVRKSSKQRLVCRLIQIT
                     CKGILLLATAVKKEHINKANERFQHPAIIIANHQSFIDILVLLSLSSKILMVTNHWVWH
                     SPFFGAIIRYVDFYYIGEGYEQYMERMRKKVKEGYVYGEVFPPYTGRRPFFRNHLPGTH
                     QTHIRVYEGRLRPYLPGKEHDGQSCFLRSSDPKLYL"
     CDS             complement(7286..8476)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123:polyprenol-monophosphomannose synthase ppm1
                     (Score: 83.2; E-value: 3.8e-25)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg831_6"
                     /sec_met_domain="Glycos_transf_2 (E-value: 8.2e-30,
                     bitscore: 93.8, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEQISTAYWHEKLKQLGIIVIIPSYNNGKTLAEVIASVRFYAPE
                     ILVVNDGSTDETPEILNQEANLHIITHPVNQGKGVALKHGLSFAKKQGFRYAITIDSDG
                     QHFASDIPVLIEAIEKEPDTLLVGSRNLTSDNMPGKNTFANKFSNFWFTLETGIKLQDT
                     QSGYRLYPIQRMNVDKWYYTAKYEFELEALVFAAWGGIPVKNIPVHVYYPPQEERVSHF
                     RPFRDFTRISILNTILVLVTFLWIVPRNFFRKLTWKNCKQFFSNHITHSPESNPRITAA
                     IMLGVFMGIVPAWGYQMLITLFLAHLFRLNKVIAIVAANISIPPMIPFLLYGSYVTGCK
                     VLGEPVNLHLNELSFENVKSVIEQYLIGSVIFAAVCSILAGTIAFILLTACRKKKI"
     CDS             complement(8473..8952)
                     /locus_tag="ctg831_7"
                     /transl_table=11
                     /translation="MLLDNFYTILSSESSDSTTWTIQIELNPDHTVYQGHFPEHPVVPG
                     VCLLQLIKECAENIRQQKLQIVQVSSCKFLSAINPIETPRIAIVLILKETEEGKFQLQA
                     EGTIKGNTVNKSIVKEDIAKEEIVKENTGKESIIKEENIKDECFIKLKAALTPKA"
     CDS             complement(8956..9516)
                     /locus_tag="ctg831_8"
                     /transl_table=11
                     /translation="MRRSLRFVSLTVLLFLGIQVQTSCSPRISGEGSTVPPVIELTQGE
                     ESQKYNIQLDFMKHHMSGMLIVRRMPDNEIRIVASTYFGLSLFDFSLHDDQFNVNSCIE
                     PMKKEKVLKLLEMDFRRLFLNGKDVRVKATKDNATQKRTSGKGFGKSVVYITGDTPGEP
                     AQIKIKHPWIRLTIRLDKLSKEI"
     CDS             complement(9491..10126)
                     /locus_tag="ctg831_9"
                     /transl_table=11
                     /translation="MRTLLLYLSLFFLSIATVHAQSMKKMVQKTEFENRLAKEAQTVES
                     IESDFTQVKYLDVFDEKVTSKGKFYYQKSNKICMEYFRPMDYLIVINGSKLKIVSDGKK
                     SIMNLSSNKMMAQMQDMLTACMIGDLSKMSSNYQLEYFEDARYYLVKIKPTNKAVQAYI
                     AGIEIYLDKKDMSVHKLRLSETATNYTEYEFYNKKFNSLKNETKFAIR"
     CDS             complement(10138..10818)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235:polysaccharide deacetylase (Score: 123.4;
                     E-value: 1.9e-37)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg831_10"
                     /transl_table=11
                     /translation="MMIVCLLLCLFLILSFLVYASYSIQSGIYLRSFCKKRTTEKVVVL
                     TFDDGPDPIQTPKVLEVLKEYQATACFFCIGHKIKGNEALLKSMVTEGHLIGNHSYSHS
                     GLFPLYGLSKMKKDLQTCQCELERVTSQPVTLFRPPFGVTNPTIAKAVRQLGYTSIGWS
                     IRTLDTQQSAPDKILARIRKRLEPGAIILLHDRMPGSDQLVKQILDLLKEQGYTVVRPD
                     KLLA"
     CDS             complement(10815..11840)
                     /locus_tag="ctg831_11"
                     /transl_table=11
                     /translation="MQPVYIQRIASIHPQGNHSQENNPKVNDSLDVAANRPFLQACEPD
                     YKDIITNATLRRRMSRIVKMGVACGLECMGEPSPEKIEGIITATGLGCLVDTEKFLNNL
                     LDNEERMLNPTPFIQSTFNTIGAQIALIHQIHAYNMTYVHRGLSFESALLDAMMKIEEG
                     SENILVGAMDEMTETSYIIQQRLGLLKGIEAGEGAQFFLLSREAGEHPLAEIRGLETFT
                     GQHTTEEISSRIIRFLQRNGLECQDIQWLVTGKNKKQSLQGDYHEQITNSIYEELETNL
                     FPESIHLSFKDECGEYPTASSYAVWKAVKTSINCTTPTNILIYNHHHSINHSLILIRKS
                     V"
     CDS             complement(11853..13160)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (152-423). E-value:
                     1.7e-38. Score: 124.4. Matches aSDomain:
                     nrpspksdomains_ctg831_12_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 255.4; E-value:
                     1.7e-77)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg831_12"
                     /sec_met_domain="APE_KS2 (E-value: 3.1e-114, bitscore:
                     371.8, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIYVTGLGVVSGIGIGVSENIEALQQGKHGIGKVTLFPTALDVP
                     VSEVKRSNEELKQLLSLPPQRTVSRTALLGMIAAKEAMEDAGLNLRISSNQPKNQLPNQ
                     SVTSQKDQQPLRIGFISATSVGGMDLSERFYESFKKNPKQGRLREVISHDCGASTELIA
                     SYLGINDFITTISTACSSAANAIMLGARLIKHGQLDAVIVGGTDALCRFTLNGFNSLMI
                     LDKIHCRPFDRSRTGLNLGEGAGYLVLQSESSLQRVPYCELSGYANTNEAYHQTGSSPE
                     GDGAFLSMSEAIASSGISPEDIDYINVHGTGTPGNDASEGMALRRIFGEHVPPFSSVKA
                     FIGHTLGASEGIEAVYSVLSIDKGMIYPNLNFTEPMPETELLSETGVKSETGLIPETSF
                     QKGLPIRHVLSNSFGFGGNDSSLLFSATNLPKRTNL"
     aSDomain        complement(11892..12704)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg831_12_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.70E-38"
                     /label="ctg831_12_PKS_KS.1"
                     /locus_tag="ctg831_12"
                     /protein_end="423"
                     /protein_start="152"
                     /score="124.4"
                     /tool="antismash"
                     /translation="HDCGASTELIASYLGINDFITTISTACSSAANAIMLGARLIKHGQ
                     LDAVIVGGTDALCRFTLNGFNSLMILDKIHCRPFDRSRTGLNLGEGAGYLVLQSESSLQ
                     RVPYCELSGYANTNEAYHQTGSSPEGDGAFLSMSEAIASSGISPEDIDYINVHGTGTPG
                     NDASEGMALRRIFGEHVPPFSSVKAFIGHTLGASEGIEAVYSVLSIDKGMIYPNLNFTE
                     PMPETELLSETGVKSETGLIPETSFQKGLPIRHVLSNSFGFGGNDSSLL"
     CDS             complement(13164..13445)
                     /NRPS_PKS="Domain: PP-binding (22-68). E-value: 5.7e-11.
                     Score: 34.7. Matches aSDomain:
                     nrpspksdomains_ctg831_13_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg831_13"
                     /sec_met_domain="PP-binding (E-value: 1.4e-11, bitscore:
                     34.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNLDQTKRELMDEVKGKLIEELNLEEITPEDIDDEAPLFGDEGL
                     GLDSIDALEIILILEREYGIKIENPSEGKQIFYSVCTLTDYIIANRKA"
     aSDomain        complement(13242..13379)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg831_13_PP-binding.1"
                     /evalue="5.70E-11"
                     /label="ctg831_13_PP-binding.1"
                     /locus_tag="ctg831_13"
                     /protein_end="68"
                     /protein_start="22"
                     /score="34.7"
                     /tool="antismash"
                     /translation="LNLEEITPEDIDDEAPLFGDEGLGLDSIDALEIILILEREYGIKI
                     E"
     CDS             complement(13438..14703)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (23-214). E-value:
                     1.9e-22. Score: 71.6. Matches aSDomain:
                     nrpspksdomains_ctg831_14_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 141.1; E-value:
                     8.5e-43)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg831_14"
                     /sec_met_domain="APE_KS2 (E-value: 1.8e-79, bitscore:
                     257.4, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGRYKRVIVAGGDILSHFITSGFLSFRSVSAHRCRPYDIQRDGL
                     SLGEACGAVLLETQGNANHIILSGGAISNDANHISGPSRTGDGLALAINQAMEEAGTLP
                     EDISFINAHGTATVYNDEMESKAIHLAGLSAVPVNSLKPYFGHTLGASGIIETILCIEQ
                     LKEGIYYGTLGYEILGVPMPITVYGTHQPMPMKCCIKTASGFGGCNAALVLSLPDAHLK
                     QKTDSPTFCKAVVESANIVTIKPGVVESQGTAIFNSSETDFAPFIREAYKHLGENNMKF
                     YKMDNLCKLGYVAAGYLLKDTNYRPEEIGIILANASASLDTDCRHQAIINKEGDKAASP
                     AVFVYTLPNVVLGEICIRHKIQGENTFFVCQQSDTASLEDYARIVMAKGKLHTCIIGWC
                     ELLDGHYQAEFKQLNNISTIYE"
     aSDomain        complement(14062..14634)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg831_14_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.90E-22"
                     /label="ctg831_14_PKS_KS.1"
                     /locus_tag="ctg831_14"
                     /protein_end="214"
                     /protein_start="23"
                     /score="71.6"
                     /tool="antismash"
                     /translation="FLSFRSVSAHRCRPYDIQRDGLSLGEACGAVLLETQGNANHIILS
                     GGAISNDANHISGPSRTGDGLALAINQAMEEAGTLPEDISFINAHGTATVYNDEMESKA
                     IHLAGLSAVPVNSLKPYFGHTLGASGIIETILCIEQLKEGIYYGTLGYEILGVPMPITV
                     YGTHQPMPMKCCIKTASGFGGCNAALVL"
ORIGIN
        1 tggtagtcat gagttgcaga atatcctttt tactgcatcc ggtggtggtg aaagacaggt
       61 actcgttgta agataaacgg tccaggtcct cggaagtgag aacgaaagtc accggatctc
      121 ccagtgtgcc ggaagtcgtt acatagtcga tgatttgctc cttgtctaca cagatgaagt
      181 cgtcgttatg aagttgcaag tctgtcttgg tggtgacagg gatttgttgc aggtcttcaa
      241 tcttctttat ctgattgatg tcaatgtggt gttcttcgaa cattcgttgg tagaacttgg
      301 agtgtgcttg caggtaggtc aacgtttggg ttaaccgttc ttcctgatag catttgatct
      361 cttccggtga gcggaactga atttcaggat tcttttccat ctttggattg tttttgaatt
      421 ttctgttgga tacgttcttt ctcttgcaac ttgggaatcg gtttctttaa tgctttttgc
      481 cagtacacga tggcttgttg cggttgctgc atagcctcgt aataatctcc catcacttca
      541 tatacataat atagagaagg attggaggct tcgtatgttt ttaaaatatg ctcttctatc
      601 ttctcctttt ttctgatctt cttcaatagg agcggagtca gcttcttata agtaagaaga
      661 tgctggaact ccggtgtttc ggtgaattca tctgccggaa tggtcaggtt agaactgtat
      721 atttcgtgtt gcaagttaat cgtgtcgtta aatatcttgt tcaggtcata agctatatat
      781 tttccacatt gccagggaga ggtagatacc cacatcaatc gtttctccgg ttggaagatg
      841 acggaatgat gggcaatgaa ttgattgata gccatttcgt tggccagtcc caagtccgca
      901 tcttgcaaac ccttgtggtt gcgcaggata gaggcggctt tagaggcatc tatcggcaga
      961 ttctcattga tgagttcttt caatcgtgca aaacggtatg gactgtccga agtacggata
     1021 ttttccatgt ttcgttcatc cttgctgaat tcctccgatt ggtaatgatt ggtgcagatg
     1081 agccggtcgg cttcttttcc tttaaagagt actgtcttct ctggggattt ttcaatgata
     1141 gcggctttgc catctttgga agaacctatc aagatggatt cggagacgaa tgtcttccgt
     1201 ttctgtgcga tggcaaaagc ctcatcaatc gttgacgcat attgcaggat ttctctggtc
     1261 agaatggaaa taggagtggc ggaacctgtt ggaacagcag acttggcggc attgatcgtg
     1321 acggtcagcc ccgtttcgtt catgccggat agtacgccta tcataccggg ccatcctacg
     1381 gaagcgaatt tataaccttg atccggtgta taaaaagcca cttgtttatt ttctgcgaag
     1441 gcatctccca catagaaatc gaagttgcgt ccgatcagta gagacgaatc tgcactttga
     1501 gttccccaag tggcaaacga actgcatcct actaacatat aatcttgcat ggcatgtccc
     1561 aggtcgtgtg ccgaatggta attcagctga cgttcgtaag gagtgccgat aaagtcgtat
     1621 tcatgggtac acgatagcga gattccgtag atctcgtcgc ggtattcttc gaggacgttc
     1681 tcacccaaat gacggttgaa taaaacgatg aagaaccgga gaaacttcag ataactgtct
     1741 gaaggaacaa tctcacgaat ctgatcgaca aatactttct cctgataatg aagcaaatcg
     1801 gaagacagtt tgccgatggc ttctcccctt tgaaaggcat cccctttcac aaacaactcc
     1861 cacaatccgc tttcgctgtg gcgcaggaag ttgccgtcat aatatcggag atcgagcgta
     1921 tcgttgtaga gcacctctgc cggaaccatg gtggtagtat ctgcatgaga cacttttgtc
     1981 atgatgatac tgggttcatg tttcggtgtc cgcatatccg ctgaaaagta gagataacag
     2041 attccggcta tcaatatcac aaggagcgac aaaagaacgc agctcgtgta cttgaatatc
     2101 tttttgattg ttttatgcat ttcctacttt tttagccaag tattcttgtc ccacaaattc
     2161 cgcacaagtg agcatggaag tcagcgttac ccccagtgcg ccatgcacgt tcaggttttg
     2221 acctgtgaga aagagattac ccaaccggct tcgtgtagac acaaaaccga tttgcggaca
     2281 tttataatct ttgataattc cgtatgcgga accgtccacc gttccggtat agtcgcgata
     2341 actcaacgga gtggtggtgt gaatctcttc tatgttgtcg gagaaatcaa tgccatggct
     2401 ccggataaag cgaagtagct gttccgtctt ttcctgtttg aaggaccggt agctttctcc
     2461 ccgatgttcg ggagtggtgt ctttccatgc agagagttcg ttcatataca tcggtgtcag
     2521 gatagaaatg acactggcgt attggctgtc ttcggaagag gcttgcatcg aaatcatgca
     2581 gttggtggtc cgtcccggat agagctgttt gtcataccac actttatgat ccccatgcag
     2641 atagaggtta cggttttggt atggagtgct cttctttttc attaccagat aaagcgtgaa
     2701 gataccgtat gtgttttcga gcgagcggat gcgggaaatg taggcattct tgatactgcg
     2761 gtttttatcc agtatctcta gggttcgttg agggtgcatg ctggaaatca caaagtcgct
     2821 ttccaatcgt ttttcaccgt tgatgatgac tccctgtact ttttcgtttt caacgatgat
     2881 gcgggtggct tcgctgttgt taagtactgt ccctccattc gctcggatca cgttaatcaa
     2941 ttccaagctg acttgcatac tgccgtccac aaaacgataa gctccttcga tgtaggaatg
     3001 gttaatcatg gcatgttggt agaaggtgga gacatctttc aagcctccgt agagcaaggc
     3061 cgagcctgcc agtacgtttt gcaaagtggg gtccggagta atatccgcaa tcagtcctgc
     3121 ggcggaggtg cagaagtatt tcattccttc cagggcaagt gtgccctgtt tcagatggtc
     3181 aacgctaatc aagttaccaa cagtctgaag ctgttcggca taacgtttca ggttttcttt
     3241 ttcgtgcggg aaggaccggc agatcgtttc gatgaattgc ggatacccca ttgcataatc
     3301 gtatgttttt cctttatagt agattgtatc gaaagcctca tcgtccaaac gtttcagctt
     3361 tagtttgtcc atgatgccga aatagcggaa atattgattc atcacttgac cttcatccag
     3421 acttcctaca taatgaatgc ctgtatcgaa taagtgtcct tttcgccggt aggtttgaaa
     3481 gcatccgccg aattgcgtgt ttttctctac gacgcatacg ctgaatcctt ctttactaag
     3541 aatcgctcca cattccagtc cgccaaggcc gcttccgata atgatgatat cgtatttatt
     3601 catgttcgtt cggttttctg aatatataaa tagtgttcga ggtatatttg tcattaggaa
     3661 tgatttctac attcattccg caggtgactg ctatttcccg cagttgggtt tctgtagtga
     3721 aatgcaattc tccggcagtc cggttgaaat tgaagatacg ggtggatagt aattccgtga
     3781 accgggtcag cctgtgtttg gacgtatttg ccgagtttcc gtcccgtatg ataatcattc
     3841 cctgcgaacg cagccggtca gcgcatttca acagcaaagt ccgttgatgt tcatagctca
     3901 tatagtgaag catatcgttc aggataaaaa catcgctttc cggtagcgga tattccaatg
     3961 cgttgccgtg cctgaactgg agatgttcgt tgcgtaacca tccgtgttgt gccaaggcta
     4021 ttttatcctc atcgtaatca attcctaaaa tttcccggtc ttcggaaagc agagacagca
     4081 tataacagag cggaccgtag ccgcagccga tgtccgtaat ttgcccttga acgggaatca
     4141 gttggttgaa cagccggtag tttctttcca tcttcacctt gatacggata taccattcta
     4201 cgaccggtcc tttatagata tagttttgga tcagagcttc gtagaaagca ggattgtccg
     4261 tcgtgttctt ttcccggcag atacgggcgt aaccttcctt catatacgcg gatatgcgtt
     4321 tggtgcgttc ctggtaggtg gttccgaaag aaaggtcgtc gcccggtata cgggggaaat
     4381 acttccccgt atacgtaccc ctcttttact tttttccgca tccgttccat atattgttcg
     4441 tagccttcgc ctatgtaata gaaatcgaca tagcggatga ttgctccgaa gaaaggagaa
     4501 tgccataccc aatggttggt taccatcagg attttagacg aaagagacag caataccaga
     4561 atatcgatga acgactggtg gttggcgata ataattgccg gatgctggaa acgctcgttg
     4621 gccttgttga tatgttcttt tttgacggca gtggctaaca acagaatccc tttgcaggtg
     4681 atttgtatca gtcggcatac caaacgttgt ttgctgcttt tccgcacagg caccaaataa
     4741 aggacagcga tcagtacacg gaggaagata caaccgataa agaaaagcag gaagagcaat
     4801 acggtccgta tcagcccgat aagcgtataa ggcggcaatc ctttggaagc gggtcctgca
     4861 atgaagaacc ggaaaatgag tggctgaatg gtataggcta ccaacaccac tgctatcatg
     4921 ccgagaatgg aaatcagtga aatggattgc aaagccggat gcttggcaaa aacaagtgct
     4981 cccataccga caactgtggt gaaagcagag aagaagatgg ctgttttgtg agaattcagt
     5041 accttctgac ctgtacggta tttgttttgt agcccgtcca taatgaagat actgaaatcg
     5101 tctccaatgc caaagataaa ggtggacagg ataatgttga tgatgttgaa ctcaatcccc
     5161 aaaattccca tcaatcccaa gatgattacc cagctgacca gcatcgggag aaaactcatc
     5221 aaggtaagtt cgatacgtcc gtatgagaac cataatgcga agaatatcag gaaagaagag
     5281 atatacagaa tcaggtaaaa gtcgtcattg atggcagata cccatttatt ggcaaagtag
     5341 gaacggtcga agatgactac atcctgggtt ttgctgaagt tctgatacac ggtttcctta
     5401 ttctggtcgc taatccgtat ctggctgata agcatggtga tggaatcggc agaagtttgc
     5461 cattcgttca gtagcttgcc ggataaatcg tcttcttgtg cggtgtagtg atattcaccg
     5521 aaaggttggt ttagccattg ataaaaggga tcgaagcttc ccggacggaa acggtattca
     5581 gtggcagctg tttccagttg tttacggatt tgctgttgtt tttcatctgt ccagtagtct
     5641 ttccatcttt tcaggcgtag ctgttgctct tgtggagaaa tcagaaactg tgaggcggaa
     5701 gcataatctt taatcagtcc ctgatccttc agtgtcgata acttctgatt ggttattgca
     5761 taagtttcgg tagcctgatt catgtctttg cctacgctga caaaaagcac tgtcttttcg
     5821 tcgctgtcga agagctgcat taatttctct tccgattgtt tgagatgttg aggttcataa
     5881 ttgaggctca tcatgtcgtt gttgaagccg accttttgtg aggtaaacaa acagataatt
     5941 gtaatgagga gaataccgcc taccaaccat ttattctttt cgtaagaata tgcgtttatt
     6001 ttctcgatga tgcgtaatac gcgtccctgt ttgacgtctg cctgtccttt caggaaatga
     6061 ggcaggtaaa tgaggcaaaa aagagtagta cccaccaatg ccagggaagc gaacaacccg
     6121 aaatcgcgta acagatcgga actggtgaat atcaatccca taaatgcgcc gatagtggtg
     6181 aaactaccta ctgtaagcgg ataggctatc tctttaatca gttgttgcac ggtggaaaca
     6241 tggttctgat gtgccaacat gtggatggaa tagcttagcg caatacccat cactgccgaa
     6301 ccggctccca cggcaatggc cgagatgctt cctttgataa agaaaatcag aaacagggcg
     6361 aacaatcctc cgaagagtac cggagtaata atcagtggta tcgatcgctt ccgtttaaac
     6421 acgagtgaga taaatactat gatgataagc agtgccaggg aagaagtcag aatcgtgtct
     6481 ttcttgatct gacgggcgtt gtagactcct acggagggac cgccgaaata ttcggctcga
     6541 atggtaggag attctccctg tacgtgttgg agttcttctt cgagtatttt tatcagttcg
     6601 tcattctttc cggtactgcc tgtgctgaat accggggtaa tgaacataag caaggtggaa
     6661 ccgtctttgg aaaagatgtg ttcgtcataa atctcgtagt tggcttccaa ctggaaatcc
     6721 tgcagatgtt tcagggcttc acttcccagt ccgagcgggt cccggagaat ataacttctt
     6781 aatgcgattc cggcaggaga gaggagattg gtatagttct tctgcatgat agcttgtata
     6841 cctttctctg tcaataggga atcgaatcgt tgataatccg tatctgtcag gaaaagcggg
     6901 agatgctcgt agacaaagtc tgtggctcct ccgatgaggc tttggtctac ctgtgcgaaa
     6961 attcctttaa tcagggttcc tccggctttt tctgtcaggg tttgttgcag tcgtccggca
     7021 gcttctatca gggaatcagg ttctacccgg tgacaggtat ctgccgagga tagcataatg
     7081 ataatcttat ccttgatttt gagattgtcg aataccttga ttgtgttttg agaatctttg
     7141 gtgtcgggga agaattgtgt gatgttctct tcgaacctta cttgcagggc aaagaacccc
     7201 atcaacagga cacaactgat gagtgacaaa tagaacagaa tcttgtgcct ctcaaaataa
     7261 tcatatagtc cgataaaaaa ctgggtcata tctttttttt cctacacgcc gtgagcagaa
     7321 tgaacgcgat ggttcctgcc agtatgctgc atacggctgc aaagataaca cttcctatta
     7381 aatattgctc tatgactgat tttacatttt caaaagaaag ttcgtttaag tgcaggttta
     7441 cgggttctcc cagtacttta cagccggtta cataacttcc gtacagtaaa aatggtatca
     7501 tcggagggat gctgatgttg gctgctacaa tagctatgac tttgtttaat cggaacaaat
     7561 gcgccaaaaa caacgtaatc agcatttgat atccccatgc cggaacgatg cccataaata
     7621 cgccgagcat gatggctgcc gtaattcgcg ggttagattc gggggagtgg gtgatgtggt
     7681 tggagaaaaa ctgcttgcaa ttcttccagg tcagtttacg gaaaaagttt cgtggtacga
     7741 tccaaaggaa agtgacgagt accagtatcg tattcagaat actgatacgg gtgaaatcac
     7801 ggaacgggcg gaaatgagaa acccgttctt cctgtggcgg ataataaacg tgtaccggaa
     7861 tatttttaac gggaatgcct ccccatgctg caaaaacaag tgcttccagt tcgaactcat
     7921 atttggcagt gtaataccac ttgtccacat tcatgcgttg gatagggtag aggcggtagc
     7981 cggattgcgt atcttgtagt ttgataccgg tttcgagggt gaaccaaaag ttggaaaact
     8041 tattggcaaa ggtattcttt cccggcatat tgtccgaggt cagattacgg gagcctacca
     8101 gtaacgtgtc cggttccttt tctatggctt caatcaatac gggaatgtcc gaagcgaaat
     8161 gctgtccgtc ggaatcaatg gtgatggcat atcggaatcc ttgcttcttt gcgaaagata
     8221 gtccatgttt caaagctacc ccttttcctt gattgacagg gtgggtgatg atgtgaagat
     8281 tagcttcctg attcagtatt tcaggtgttt catccgttga accgtcattg acaacaagga
     8341 tttccggtgc ataaaaacgt acacttgcta tgacttctgc cagtgtcttg ccattgttgt
     8401 aactcgggat gatgacgatg atccctaatt gtttcaactt ttcgtgccaa taggctgtac
     8461 ttatttgctc cttcatgctt ttggggtaag tgcagctttt agtttaatga aacattcgtc
     8521 ttttatattt tcttccttta taatgctttc ttttcctgtg ttctccttta caatttcttc
     8581 ttttgcaata tcctctttca caatgctttt atttacggta tttcccttta tagtaccttc
     8641 cgcctgtaac tggaacttgc cttcttctgt ctctttgaga atcagtacga ttgctatccg
     8701 aggcgtttct ataggattga tagccgaaag aaacttgcag gaagacactt gtactatttg
     8761 caacttttgc tgacgaatat tttctgcaca ttccttgata agttgcaata gacaaactcc
     8821 gggaactacc ggatgttcag gaaaatgtcc ctgataaaca gtgtggtcag gattcaactc
     8881 tatctgaata gtccaggtag ttgaatccga tgactcggag gaaaggatag tatagaagtt
     8941 atcaagtagc atatattaaa tttctttaga tagtttatcc agacggatcg ttaaccgtat
     9001 ccacggatgt ttgattttta tttgtgccgg ttcacccgga gtgtcgccgg taatgtagac
     9061 cactgatttt ccaaagcctt ttccactggt tcttttttgg gtagcattgt ctttggtggc
     9121 tttcacacgg acgtcttttc catttaagaa caaacgcctg aaatccatct ctaacagttt
     9181 caataccttt tcttttttca taggttcaat gcagctgttg acattaaatt gatcgtcatg
     9241 cagagaaaaa tcgaaaaggc ttaacccgaa gtaggtagac gccacgatcc ggatttcgtt
     9301 atcaggcata cggcgtacta tcagcatacc actcatgtga tgtttcatga aatccagttg
     9361 gatattgtat ttttgtgatt cttctccttg tgtcagttcg ataacaggag gcacagtact
     9421 gccttccccg cttattcgtg gagagcagga cgtttgaacc tgtattccta agaataacag
     9481 aaccgtcagg ctaacgaatc gcaaacttcg tctcattctt cagagagttg aactttttat
     9541 tatagaattc gtattctgtg tagtttgtag ctgtttcgga cagacggagt ttgtgcaccg
     9601 acatatcttt cttgtccaaa taaatttcga taccggcaat ataggcttgt actgctttgt
     9661 tagtcggctt aattttaacc aaataatatc gtgcgtcttc aaaatattct agctggtagt
     9721 tggatgacat cttagacagg tcgcctatca tacacgcagt tagcatatcc tgcatctgtg
     9781 ccatcatttt gttcgaactt aggttcataa tacttttctt gccatccgat acaattttga
     9841 gtttactgcc atttatcacg atgagataat ccatcgggcg gaagtattcc atacagattt
     9901 tattgctttt ttggtagtag aacttccctt tggaagtaac cttttcgtcg aatacatcga
     9961 gatatttcac ttgggtaaaa tcgctttcga tagactctac ggtttgtgcc tcctttgcca
    10021 agcggttttc aaactcggtc ttttgcacca tctttttcat gctctgtgca tggacggtgg
    10081 cgatagacaa gaagaaaagc gataagtata gtaataaagt tctcatacat ttttatttta
    10141 tgccaatagt ttatccggac ggacaacggt atatccttgt tcttttagta aatccagtat
    10201 ttgtttcact aactggtcgc tgccgggcat ccggtcgtgc aacagaatga tggctcccgg
    10261 ttcaagacgt ttccgaatcc tggcaagtat tttgtccgga gctgactgtt gcgtatctaa
    10321 tgtacggatg ctccatccga tcgaggtata tcctaactgt cggacagctt tcgcaatcgt
    10381 aggattagtg acaccgaatg gcggacgaaa caaagtaacc ggctgcgaag ttactcgttc
    10441 tagttcacac tgacaagttt gcaggtcttt tttcatttta gagagtccat atagtggaaa
    10501 taaaccggaa tgactatatg aatgattccc aattagatga ccttctgtta ccatactttt
    10561 caataaggct tcatttcctt ttatcttgtg tccgatacag aaaaaacagg cagttgcctg
    10621 atattctttt agtacctcca atactttggg cgtttgaatg ggatcgggac cgtcgtcaaa
    10681 agttaggacg acaacttttt ccgtagtacg ttttttgcaa aacgatcgta gataaattcc
    10741 cgactgaatg ctataggaag cataaacgag aaaggacagt atcaagaata aacatagaag
    10801 gaggcaaaca atcatcatac gcttttccga attagaatca atgagtgatt gatggagtgg
    10861 tgatgattat aaatcaatat attggtaggg gtagtgcagt ttattgatgt ctttactgct
    10921 ttccatacgg catacgatga ggcggtagga tattctccac attcgtcctt aaaactaaga
    10981 tgaatacttt ccgggaaaag gttggtttca agctcttcat agatagagtt agtgatttgc
    11041 tcgtggtaat caccttgaag ggattgtttt ttgttctttc cggtaactaa ccattgaata
    11101 tcctgacact ctaatccgtt tcgttgtaaa aaacgaataa ttcgggaact gatttcttct
    11161 gtcgtatgtt gtcccgtgaa agtttcaagt cctcgtattt ctgctaacgg atgctctccg
    11221 gcttcccggc ttaataggaa gaattgagcg ccttctccgg cttctattcc tttcagcagg
    11281 cccagtcgtt gctgaatgat gtaactggtt tctgtcattt cgtccatggc tcccaccagt
    11341 atattctcgc ttccttcttc tattttcatc atggcatcca gcaaagcgct ttcaaaactt
    11401 agtccccggt gaacataagt catgttatag gcatgtattt gatgaattaa agctatttgt
    11461 gcaccaattg tattgaatgt cgactgaata aaaggagtag gattcagcat ccgttcttca
    11521 ttatctaaca ggttgttcag aaacttttcc gtatcaacca ggcagcccag ccctgtggct
    11581 gtgataattc cttctatctt ctcgggagat ggttcgccca tacattccaa tccgcaagcc
    11641 actcccattt tcacaatacg gctcatgcgt ctgcgcaaag ttgcgttggt aataatatcc
    11701 ttataatcgg gttcacaagc ctgaagaaaa ggacggtttg ctgcaacatc gagcgaatca
    11761 tttactttcg gattattttc ttgtgaatga tttccttgtg gatggataga agcgatgcgt
    11821 tgaatataaa ctggctgcat aggctcaaaa acttaaaggt tcgttcgttt tggtaaattc
    11881 gttgcggaaa agaggagcga cgagtcgttt cctccgaagc cgaaagaatt ggataataca
    11941 tggcggatcg gcaatccttt ctggaaagat gtttccggta tcaatcctgt ttctgatttt
    12001 actcctgttt ctgacaacag ttctgtttcc ggcataggct ccgtgaaatt cagattcgga
    12061 taaatcatgc ctttatctat ggaaagaacg gaataaacag cttcaattcc ttcggaagct
    12121 cctaaagtgt gtccgataaa agcttttacc gaactaaacg gtggaacatg ttctccgaag
    12181 attcttcgca atgccattcc ttccgatgcg tcattaccgg gagtacctgt cccatgtacg
    12241 ttgatataat caatatcttc aggagaaatg ccactggaag cgatggcttc actcattgat
    12301 agaaaggcac catctccttc gggagaactt cctgtttgat gataagcttc atttgtatta
    12361 gcataaccgc ttagttcaca gtaaggaact ctttggagtg aactttctga ttgaagcact
    12421 aaataacccg cgccttctcc caaatttaat ccggtacgcg aacggtcaaa aggacgacaa
    12481 tgtattttat ccaagatcat gagagagttg aacccattga gcgtaaaccg gcaaagtgca
    12541 tccgtacctc cgacgataac agcatccagt tgtccatgtt ttatcagtct cgctcccaac
    12601 ataatagcat tggctgccga tgaacaggct gtactgatgg tggttataaa atcattgata
    12661 cctaaatacg aagctattaa ttcagtgctg gctccacagt cgtgtgaaat cacttcccgc
    12721 aatcgtccct gtttcgggtt tttcttgaaa gattcataga aacgctcgct taaatccata
    12781 ccgccgacag aagtggcgga aataaaacca atacgtaacg gttgctggtc tttttgcgag
    12841 gttactgact gattcggtaa ttgatttttt ggctgattgg atgatatacg caagtttagt
    12901 cctgcatctt ccatcgcttc tttggcggct atcatgccta gcaatgctgt gcgtgatact
    12961 gtacgctgcg gaggtaaaga taatagttgt ttaagttctt cattgctacg tttcacttca
    13021 gatacgggta catcgagagc agtcgggaaa agagttactt ttccgatacc atgctttcct
    13081 tgttgtagtg cctctatatt ttcggaaact ccgatgccga tgcccgaaac aactcccaat
    13141 ccggtgacgt aaatcttcat aagttaagct ttccgattag caatgatgta gtcagtcagt
    13201 gtacataccg agtagaagat ttgtttgcct tcactgggat tctctatttt aataccatat
    13261 tcgcgttcca aaatcaggat gatttcgagt gcgtcaatgg agtcaaggcc aagaccttcg
    13321 tcgccaaaca gaggggcttc atcgtcaata tcttccggag tgatttcttc aaggttcaac
    13381 tcttcgatta gtttaccttt cacttcgtcc atcagttctc ttttggtttg atctaaatta
    13441 ttcataaatc gttgatatat tattaagttg tttaaattct gcttggtaat gtccgtctag
    13501 tagttcgcac caacctataa tgcatgtgtg taacttacct ttcgccatca caattcttgc
    13561 gtaatcctct aaggaagcag tgtcggattg ttgacaaaca aagaatgtat tctctccctg
    13621 aattttgtgt cgtatacaga tttctcccaa tactacattg gggagagtgt agacaaatac
    13681 ggcaggactg gcggctttat ctccttcttt attgatgata gcttgatgtc tgcagtccgt
    13741 atccaaagag gcggaagcat tggctaaaat gattccaatc tcttctggac ggtagttggt
    13801 atctttcaat aaatatccgg cagctacata tcccagctta caaagattat ccatcttgta
    13861 gaacttcata ttgttttctc ccagatgctt gtatgcttcc cggataaatg gcgcaaagtc
    13921 agtctccgaa gaattgaata tagctgttcc ttggctttct accactcccg gtttgatcgt
    13981 gactatattg gctgattcca cgacagcttt gcaaaatgtc ggagaatcgg ttttctgttt
    14041 caaatgagca tctgggagag ataataccag tgcggcatta cagcctccga aaccggaagc
    14101 ggttttgata cagcatttca tcggcatcgg ctgatgagta ccataaacgg tgataggcat
    14161 gggaacaccc agtatctcat atcctaaagt tccgtagtat attccttctt ttagttgctc
    14221 tatgcaaagt atggtttcga taatgcccga agctcctaat gtatgcccga aataaggctt
    14281 aagactattc accggaactg cagacaatcc tgccaaatgt atggctttgg attccatttc
    14341 gtcattataa accgtagctg ttccgtgtgc attgataaag ctgatatctt cgggaagtgt
    14401 tccggcttct tccattgcct gattgatagc cagcgccagt ccgtctcctg tccgggaagg
    14461 accggatata tggttggcat cattgctgat cgctcctccg gatagaataa tatgatttgc
    14521 gtttccttga gtttctaaaa gcacagctcc acaggcttcg cctagactta agccgtcccg
    14581 ctgtatatcg tatggccggc atcggtgtgc gctgactgac cggaaagaca ggaaaccgct
    14641 ggtaataaaa tgagaaagaa tatccccgcc agcgacaatc acccgtttgt aacgccctga
    14701 ttc
//
