LOCUS       c00278_gnlPro..        11079 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KDKJNLJD_278.
ACCESSION   c00278_gnlPro..
VERSION     c00278_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 08:00:29
            Original ID  :: gnl|Prokka|KDKJNLJD_278
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11079
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11079
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:4626]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..4626
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..11079
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11079
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             2..430
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg278_1"
                     /sec_met_domain="Glyoxalase_4 (E-value: 1.6e-26, bitscore:
                     82.1, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="IYIVMKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQK
                     VRTAFLKVGDVKIELLEPTSPESTIAKFIEKNNGNGGMHHLAFAVEDGVAGALAEVEEK
                     GIRLIDKAPRKGAEGLNIAFLHPKSTLGVLTELCEKPE"
     CDS             489..2042
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg278_2"
                     /sec_met_domain="CT_Btheta (E-value: 9.4e-292, bitscore:
                     956.9, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIDRRAAARLGGGEKAIAKQHEKGKYTARERIAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYIFAQDFTVSAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAQTEEEGLALIRKLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDNPN
                     KPYDMYEVIGAIIDNGEFLEIQKDYSKNIIIGFARFNGQSVGIVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKEQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRIIRALQQLQTKKLTNPAKKHGNIPL
                     "
     CDS             2074..3006
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg278_3"
                     /sec_met_domain="OAD_gamma (E-value: 7.6e-18, bitscore:
                     54.3, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLMLVLGFCSSCKEQKSNNKLLLNEVLVNNESNYQ
                     DDYGVHSAWIEIFNRSYGSADLAGCYLKFSSQPGDTASYFIPKGDVLTLIKPRQHALFW
                     ADGEPRRGTFHTNFKLDATNANWIGLYDSGKKLLDQVIVPAGTLKANQSYARVSDAADQ
                     WEVKGGSEDKYVTPSTNNKTIDSNAKMEKFEEHDSVGIGMAISAMSVVFCGLILLYISF
                     KIIGKISVNLSKRNAMKAKGITDKQEAKEKQLGQAPGEVFAAISMAMHEFQSDVHDVED
                     TILTITRVKRSYSPWSSKIYTLRETPHKK"
     CDS             3030..3464
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 67.3; E-value:
                     2.7e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg278_4"
                     /sec_met_domain="Biotin_lipoyl (E-value: 3.9e-22, bitscore:
                     67.3, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNVYKVAIGDIEDNIAHVEVNGTPYKVEMEKAPKVV
                     VKPVARPAATSAPAAPATPVVKPAAASTGKSGVKSPLPGVILDIKVNVGDTVKKGQVII
                     ILEAMKMENNINADKDGKITAINVNKGDSVLEGTDLVIIE"
     CDS             3466..4626
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg278_5"
                     /sec_met_domain="OAD_beta (E-value: 3.5e-153, bitscore:
                     498.9, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEFITFLGNNLADFWTYTGFANATVGHVVMLLVGLFFIYLAVAK
                     EFEPMLLIPIGFGMLIGNIPFNMEAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLVGAAAQFGIFGAYMIALAIGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRWLTSKNERLIRMKPPRVVSHTEKVMFP
                     IIGLLLTTFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDTITILLGLTVGAS
                     TQASEFLTLDSIKIFGLGALSFVIATASGVIFVKIFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             4796..6148
                     /locus_tag="ctg278_6"
                     /transl_table=11
                     /translation="MRKLFISLCFSACCSLLAAQTTNPIQEAMANYDYETALMLIDQET
                     PTVPLLYQKGKALKGLGNNLEALSVFQEVVAQDSLNPRAYIEAAECCKSLAKYSEALDY
                     YQNALHINPDNKYARIQYISLLMNMKRYRESLKESNLLAERDSSAYVLHLRAESMGQVY
                     DNTEIMHVIDAYLDIQKRYPNDYLSAAKLGNIYVAGHQYEDAINITEKYRSIDSTNVLV
                     NRINAQAYCLNKDYPKAIERYEQLLQEKDSSFQTCFYAGISYYALEDFYPAHDLLERAL
                     KDDNTNINVLYYLGRACSKTSWKEDGVTYLETAVSLAMPSDSVMSRLYVGLADCYKMAF
                     QYTDQANTLLTQYEKYDRQKHKLLYDAAFIYYYYLKDVSKAERYLTAYLKTRPKNSKDK
                     VQEVDADGVPIIGEDNRYNAAENWLKDIREKRKKEDFFKGKVDTASVTPIK"
     CDS             6259..8109
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg278_7"
                     /sec_met_domain="Alpha-amylase (E-value: 1.6e-64, bitscore:
                     207.8, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVFLILGTLLLSLSTYAAMNVNKIDPPFWYTGMQNPELQLMVY
                     GEGIGNAAVSVNYPGVSLSSTVKLESNNYLLVYLKLDKDVKPGKFNLTFTEGKKKLVKE
                     YELKARNKKGCEHKGFDASDALYLLMPDRFANGNPDNDQIAGMAEYKIDRKDPNARHGG
                     DLAGIEQHLDYFSDLGVTALWFTPVLENNMTGGSYHGYATTDYYKVDPRFGTNEEYKQL
                     IEKAHARGIKIVMDMIFNHCGVEHVWIKDMPSKDWFNNPDHENNFVQTSFKLTPHVDPY
                     TSQYDADQMNDGWFVPSMPDLNQKNPHVYRYLVQNSFWWIEFANIDGIRMDTYPYADYD
                     AMSNWMKELNEEYPNYNTVGETWVTEPAYTAWWQKDSKLSAPKNSNLKTVMDFSFFDKI
                     NTAKNEQTETWFKGLDRIYNNFVYDFLYPNPASVLAFIENHDTDRFLGEGNNLPMLKQA
                     STLLLTTRRIPQLYYGTEVMMNGVKSKSDGYVRKDFPGGWTGDATNALTPAGRTKIQNE
                     CYDFYKTILNWRKGNDVIAKGSMVQFMVQNGVYAYARQYEGKTIFVMLNGTDAETTVPL
                     KFYKEILKDSKQGKDILSGKAITFGEELKMGPRESLVIEL"
     CDS             complement(8580..9590)
                     /locus_tag="ctg278_8"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTREMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCKHPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYEENVALTKKVVDYAHQFDVTVEGELGVLAGVEDEVSAEHHT
                     YTNPEEVIDFATRTGCDSLAISIGTSHGAYKFKPEQCHVDPATGRLVPPPLEFAVLDAV
                     MEKLPGFPIVLHGSSSVPQEEVDTINKYGGKLEAAIGIPEEQLRKAAKSAVCKINIDSD
                     SRLAMTAAIRKTFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSENKLAQLD"
     CDS             complement(9873..10880)
                     /locus_tag="ctg278_9"
                     /transl_table=11
                     /translation="MRKLLVLCSFWLCVATLGAQNAERKLYSVAFYNLENLFDTIHDAG
                     KNDYEFLPDGSYQWTAKKYESKLQNLSKVLGSLSRDLVPEGPAFIGVAEAENSRVLEDL
                     VKQPAISNYEFVHYEGPDRRGIDCALLYDPKQFSVTHSKLVLSTPFEGDTVHLTRGFLI
                     VDGQLAGERVCVIVNHWPSRGAKSPVRVHAARQVKALKDSLMRSDKKLKLIVMGDMNDD
                     PMDESMEVLGARKYPKQVKKGEFYNPWWETLEDKGVGTLLYRGKWNLFDQIVISKPLLK
                     AKKGLRYDHNEVFIRDYLIQQDGKYKGSPLRTHGGRTWLNGYSDHLPTIIYLKN"
ORIGIN
        1 aatttatata gttatgaaga tttcacacat tgagcatctg ggcattgccg ttaagagcat
       61 tgaagaagcc cttccgtact acgaaaacgt tttaggtttg aaatgctaca acatcgaaac
      121 cgtggaagat cagaaagtta gaaccgcttt cctgaaagtg ggcgatgtaa agatcgaatt
      181 gttggaacct acttctcccg aaagcacaat tgccaagttc atcgaaaaga acaacggtaa
      241 cggtggcatg catcatctcg cattcgccgt tgaagacgga gtggccggtg cgcttgccga
      301 agtcgaagaa aaaggtatcc gccttataga caaagctccc cgcaaaggtg cagaaggtct
      361 gaacattgca ttcctacatc cgaagtcaac tctcggtgtc ctgactgagc tttgcgagaa
      421 accggaataa gcaagactgt aaaatcatca aatcataaat tgtataaaca cttaaagaat
      481 ataaattcat gagtaatcaa cttgaaaaga ttaaagagct tatagaccgc cgcgctgcag
      541 cacgtctcgg tggtggtgaa aaagcgattg caaagcaaca cgagaagggt aaatatacag
      601 ctcgtgagcg catagccatg cttctcgacg aaggcagttt cgaagaaatg gacatgttcg
      661 tagaacatag atgtacgaac ttcggcatgg aaaagaaaca ctaccccggt gacggtgtag
      721 taaccggttg cggtacaatc gaaggccgtc tggtttatat cttcgcacag gacttcacag
      781 tttctgccgg ttcactgtcc gaaaccatgt ctctgaaaat ctgtaagatt atggaccaag
      841 ccatgaaaat gggtgctccg tgtatcggta tcaacgactc gggcggtgca cgtattcagg
      901 aaggtattaa tgccttggct ggctacgctg aaatcttcca acgtaacata cttgcttcgg
      961 gtgtcattcc gcagatttcc ggtattttcg gtccttgtgc cggtggcgcc gtttactctc
     1021 ctgccttgac agactttact ttgatgatgg aaggtacatc ctacatgttc cttaccggtc
     1081 cgaaggtagt aaagactgta accggagaag acgtaagcca ggaaaacctg ggtggcgcga
     1141 gcgttcactc caccaaatct ggtgttactc attttactgc acagacagaa gaagaaggtt
     1201 tggctcttat ccgcaaactg ttgagctaca ttccccagaa caacctggaa gaagctccct
     1261 atgtagactg tacagaccct atcgaccgtc tggaagattc cctgaacgac atcattcctg
     1321 ataacccgaa caagccgtac gatatgtacg aggtaattgg tgctatcata gataatggtg
     1381 agttcctcga aatccaaaaa gattattcaa agaatatcat tattggtttc gcacgtttca
     1441 acggacagtc cgtaggtatt gttgccaacc agccgaagta tctggcaggt gtgctcgaca
     1501 gcaacgcatc ccgcaagggc gcacgcttcg tccgtttctg cgacgccttc aatattccta
     1561 tcgtatcatt ggtagacgta ccgggattcc ttccgggaac cggccaggag tacaacggcg
     1621 tcatcctgca cggtgccaaa ctgctgtatg catacggtga agctactgta cccaaggtta
     1681 ccatcacact gcgtaaatcc tacggtggtt cgcacatcgt gatgagctgt aagcagctgc
     1741 gtggcgacat gaattatgct tggcctactg ctgaaatcgc tgtaatgggt ggtgcaggtg
     1801 ctgtagaagt attatatgcc cgcgaagcca aagagcagga aaatccggct caattcctgg
     1861 ctgaaaaaga ggctgaatac accaagttgt ttgccaatcc ttataatgca gctaaatatg
     1921 gctacattga tgatgttatc gaaccgcgta acacacgttt ccgcatcatt cgtgccctgc
     1981 aacagttgca aaccaagaaa ttgactaacc cggctaagaa gcatggtaat attcccttgt
     2041 aatcaagctt ttcacactaa aacaagaacg attatgaata aaacaaaaat cggaatattc
     2101 ctttcattga tgctggtgtt gggcttttgc tcttcttgca aagaacagaa atcgaacaac
     2161 aaactgctgc tgaatgaagt gctggtcaac aacgaaagca actatcagga tgactacggt
     2221 gtgcacagcg catggattga aatattcaac agatcatacg gcagcgccga ccttgcaggt
     2281 tgctatctga aattcagcag ccagccgggt gatactgcca gttatttcat tcccaaaggt
     2341 gacgttctga cactcataaa accacgtcag catgcacttt tctgggctga tggagaacca
     2401 agacgcggta catttcatac gaacttcaaa ctggatgcca caaatgccaa ctggattggg
     2461 ttgtatgatt ccggcaagaa attgcttgat caagtcatag tgcctgccgg tactttaaaa
     2521 gccaaccaat cctatgcccg tgtcagtgat gcagccgacc aatgggaagt aaagggtgga
     2581 agcgaagata aatatgtcac tccgagtacc aacaacaaga ctatcgacag caatgccaaa
     2641 atggaaaaat tcgaagagca tgacagcgta ggtatcggta tggctatttc tgccatgagc
     2701 gttgtattct gcgggctgat attactctac atctccttca agattatagg taaaatatca
     2761 gttaacctca gcaaacgcaa tgccatgaaa gctaaaggta ttactgataa acaagaagca
     2821 aaagagaaac aactggggca ggctccggga gaagtttttg ctgccatttc aatggccatg
     2881 cacgaattcc aaagcgatgt acacgatgtg gaagacacga tacttaccat tacccgtgta
     2941 aaacgcagtt actcaccgtg gagttcaaag atttatacgt tgcgtgagac tcctcacaaa
     3001 aagtaagtca cccataataa aataaaacga tgaaagaata taaatataaa attaacggta
     3061 acgtatataa agttgccatt ggagatattg aagacaacat cgctcatgta gaagtgaacg
     3121 gtactcccta caaagttgaa atggaaaaag caccgaaggt agtcgttaaa ccggtagcac
     3181 gtccggcagc cacatccgct cctgctgctc ctgctactcc ggtagtaaaa ccggccgctg
     3241 cttctaccgg caagtcaggt gtaaaatctc cgcttcccgg tgtaatcctc gatatcaaag
     3301 taaatgtcgg cgatacagta aagaagggac aagttatcat cattttggaa gccatgaaga
     3361 tggaaaacaa tatcaatgct gataaagacg gtaagattac agccatcaat gtaaacaaag
     3421 gggactctgt tctcgaaggt actgacctcg taattattga ataatatggg agaatttatc
     3481 acatttttag gaaacaacct tgccgacttc tggacttata caggttttgc caatgcaacg
     3541 gtaggacatg tggtaatgct tctggtaggt ttgtttttca tatacttggc tgtagccaag
     3601 gaatttgagc cgatgctatt aattcctatc ggtttcggta tgctgattgg taatatacct
     3661 ttcaatatgg aagccggatt aaaagtcggt atctatgaag aaggttccgt acttaatatt
     3721 ctgtaccagg gagtaacctc cggttggtac ccgccactca tattcctggg tatcggtgcc
     3781 atgacggatt tctctgcttt gatatcgaac cccaaattaa tgttggttgg tgcagcagcc
     3841 caattcggta tattcggtgc ttatatgatt gcccttgcca taggatttga cccgatgcag
     3901 gctggtgcaa tcggtatcat tggtggtgcc gatggtccga ctgccatctt cctctcttcc
     3961 aaactggctc ctaacttaat gggtgccatt gcggtatcag cctattcata tatggcatta
     4021 gtaccggtga tacagccgcc tattatgcgt tggctgacca gtaaaaatga acgtcttatc
     4081 cgtatgaaac ctccccgtgt ggtttcacat acggaaaaag taatgttccc gattatcggt
     4141 ttgttactaa ccacattcct tgtaccatcc ggtctgcctt tgctgggtat gctgttcttc
     4201 ggtaatttac tgaaagaaag tggagttaca cgtcgtctgg caaacacagc cagtggtccg
     4261 ctgattgata ccattactat tctgcttggt ttgacagtag gtgcttctac gcaagcatcc
     4321 gagttcttaa cccttgattc aatcaagata ttcggtctgg gcgccttatc atttgtcatt
     4381 gccacagcat ccggtgtcat cttcgtgaag attttcaacc tcttcctgaa gaaaggcaac
     4441 aagattaatc cgttgatcgg taatgccggt gtatctgccg tacccgactc tgcacgtatc
     4501 tcccaagtag taggtctgga atacgatcct accaactatc tgctgatgca tgccatgggc
     4561 ccgaacgttg ccggtgtaat cggttccgct gtagcagcag gtatcctgct gggattctta
     4621 atgtaataca tttattcatt ccgttatccg gcttgaattc tgaactattt tagagcccct
     4681 tcatttttgg aggggctttt tcgttaatct atctaaaaca gattacgatt atttcgtaaa
     4741 tacattcttt ttagtaactt gcagtcagtt taacctcata taaatgatat actgtatgcg
     4801 aaagcttttt atctccttat gtttcagtgc atgctgttcg cttctggcgg cacagaccac
     4861 aaatcccatt caagaggcga tggccaacta cgattatgaa acagccttga tgctgatcga
     4921 tcaagaaacc ccgaccgtcc ccctactcta ccaaaaagga aaagcgctga aagggctggg
     4981 caataacctt gaagctctga gcgtatttca ggaagtcgta gctcaggatt ctctcaatcc
     5041 ccgggcatac attgaagctg ccgaatgctg caaatcactt gccaaatata gcgaggcact
     5101 ggattactac caaaatgcgc tccacataaa tccggacaat aaatacgcac gcatccagta
     5161 tatcagtctg ctgatgaaca tgaagagata ccgtgagtct ctaaaggaaa gcaacctgct
     5221 ggcagaaagg gacagttccg cctatgtact acaccttaga gccgaaagta tggggcaagt
     5281 ctatgacaac acagaaatca tgcatgtgat agatgcctac ctggacatac agaaaagata
     5341 tcccaatgat tacctgtctg ctgccaaact cggcaacatc tatgtagcag gccaccagta
     5401 tgaagacgcc ataaacataa cggagaaata ccgttccata gactccacca acgtccttgt
     5461 gaaccgcatc aatgcccaag cctattgcct gaacaaagat taccccaaag caatagaaag
     5521 atatgaacaa ctgttacagg aaaaagacag ttctttccaa acctgcttct acgccggaat
     5581 cagctattat gccctcgaag acttctaccc agcacacgac ctgctggaaa gggctcttaa
     5641 agatgacaat accaacatca acgttctcta ttatctggga cgcgcctgct ccaagacatc
     5701 atggaaagag gatggagtga cttatctgga aactgccgta agcctcgcca tgcccagcga
     5761 cagtgtcatg tcccgcctat atgtggggct tgcggactgc tacaagatgg catttcaata
     5821 caccgaccag gcgaataccc ttctgacgca atacgaaaaa tacgaccggc agaaacacaa
     5881 actgctctac gacgcagcct ttatctatta ttactatctg aaagatgtgt ccaaagcaga
     5941 gagatatctg acggcatacc tgaaaacccg tccgaaaaac agcaaggaca aagtgcagga
     6001 agtagatgcg gacggagttc ccatcatcgg agaagacaac cgatacaatg ccgccgaaaa
     6061 ctggctgaag gacatcagag aaaagcgcaa gaaagaggac ttcttcaagg gaaaggtcga
     6121 taccgccagc gtaaccccca tcaaatagcc ccaatgaaaa cgtttgcata atataataag
     6181 gtacagtaac ggagaaagat taactttctc cgttatttgt tttaaattag cgcaaaaatt
     6241 aaccgtaaag ttactatcat gaaaaaagta ttcttaatct tgggaacact cttactctcc
     6301 ctcagtacgt atgcagctat gaatgtgaac aaaatcgacc ctccgttttg gtacaccggc
     6361 atgcagaacc cggaactcca gctgatggtc tatggcgaag gcatcggcaa cgcggcagta
     6421 tccgtcaatt atcccggcgt ctcattgagc agcaccgtca agctggaaag caacaactac
     6481 ctcctggtct atctgaaact ggacaaggat gtaaaacccg gcaaattcaa cctcaccttc
     6541 actgaaggaa aaaagaaact cgtaaaggaa tatgaactga aggcacgcaa caagaaaggt
     6601 tgcgaacata aaggtttcga cgcctccgac gcactgtacc tgctgatgcc cgaccgcttt
     6661 gccaatggca acccggacaa tgaccagatt gcgggcatgg ccgagtacaa gatagaccgc
     6721 aaagacccca atgcacgcca cggcggtgac cttgccggca tcgaacaaca cctggactac
     6781 ttctccgacc tcggcgtcac agccctctgg tttactccgg tactggaaaa caacatgacc
     6841 ggcggttcct atcacggcta tgccaccaca gactactaca aggtagaccc gcgcttcggt
     6901 accaacgaag aatacaagca actgattgaa aaagcccatg cacgcggcat caaaatcgta
     6961 atggacatga ttttcaacca ctgcggcgta gagcatgtat ggattaagga catgccctcc
     7021 aaagactggt tcaacaaccc cgaccacgaa aacaacttcg tgcagacctc cttcaaactg
     7081 accccgcacg tagaccctta tacttcccag tacgatgccg accagatgaa cgacggctgg
     7141 ttcgtacctt ccatgcccga cctcaaccag aagaaccctc acgtttaccg ctacctggta
     7201 cagaacagtt tctggtggat tgaattcgcc aacatcgacg gcatccgcat ggacacttac
     7261 ccgtatgccg actatgatgc catgagcaac tggatgaaag agctcaacga agaatatccc
     7321 aactacaaca ccgtgggcga gacctgggtt accgaacccg cctacaccgc ctggtggcag
     7381 aaggattcca agctatcagc ccccaagaac agtaacctca agaccgttat ggacttcagc
     7441 ttctttgaca agataaacac cgccaagaat gaacagaccg aaacttggtt caagggactg
     7501 gaccgcatat acaataactt cgtatacgac ttcctctacc ccaaccccgc ttccgtactg
     7561 gcattcatcg aaaaccacga caccgaccgc ttcctgggcg aaggcaacaa ccttccgatg
     7621 ctgaagcaag cctctaccct gctgcttacc acccgccgca ttccgcaact ctactacgga
     7681 acggaagtca tgatgaatgg cgtgaagagc aagagcgacg gctatgtccg caaggacttc
     7741 cccggcggat ggaccggtga cgcaacaaac gcactgaccc cagccggacg taccaaaata
     7801 cagaacgagt gctacgactt ctacaagacc atcctaaact ggcgcaaagg aaacgatgtg
     7861 attgccaaag gcagcatggt gcagttcatg gtacagaatg gtgtttatgc ctacgcacgc
     7921 cagtacgaag gcaagacgat attcgtgatg ctgaacggta cagatgcaga gaccaccgtt
     7981 cctttgaaat tctacaagga aatcctaaaa gacagcaagc agggaaaaga tattcttagc
     8041 ggcaaggcca tcaccttcgg tgaagagctg aaaatgggcc ccagagaatc attagtgata
     8101 gaattataac gcgcactcca cacagagagc tcattcttgc aaatctccct tgcagatagc
     8161 ttgcagacac ctcgcctgcc agccatctgc aagggatttt tagtatggaa taggtgtcac
     8221 ggggatatgc ttttcaccgg tctcaaatat agctaatctg ttagttcata acggtgaaca
     8281 ctttgttcca gtatagagaa acaaagtgtt cggatatgta gaaacaaagt gttcttacgt
     8341 attggaacga agtgtttttg catattggaa cgaagtgttc tctttattga aacaaactgt
     8401 tcagttaagg gaaacagact gttttgttaa aggaaacaga ctgttgtaca cgttgaaaca
     8461 tccgcttctg aaataaccgg cgaacttaac catcccacaa caccggccta tatataacaa
     8521 gtcagccctt gcaacatcaa tattgcaagg gctgacgcta tattcggatt atctttcgat
     8581 tagtccagtt gagccaattt gttctctgaa ccaagcacgt tgatgatttt atgcttgtac
     8641 agtttttcca tattgtcacg agccggaccc agatacttac gcgggtcgaa ttctgccggt
     8701 ttttcagcaa atgtcttgcg gatagcagct gtcatagcca gacgtgagtc agagtcgatg
     8761 ttgattttgc aaacagcaga cttggcagcc ttacgcaact gctcttcggg gataccgata
     8821 gcagcttcca gcttaccacc atacttgttg atagtatcaa cttcttcctg aggaactgaa
     8881 gaagaaccgt gaagaacgat ggggaatccc ggaagtttct ccattacagc atccagaacg
     8941 gcaaattcca aaggaggagg aaccagacga ccggtagcag ggtcaacgtg gcattgttcg
     9001 ggtttgaact tgtatgcacc atgagaagta ccgattgaga tagccagtga atcgcaacct
     9061 gtacgggtag cgaagtcaat aacttcttca ggattagtat atgtatggtg ttctgcagaa
     9121 acttcatctt ctacaccggc caatacaccg agttcgcctt ctacagttac gtcgaactga
     9181 tgggcatagt caactacctt cttagtcagt gcaacgtttt cttcgtacgg aaggtgtgaa
     9241 ccgtcaatca ttactgaaga gaaaccggag tcgatacagc tcttgcaagt ttcgaatgta
     9301 tctccgtggt caaggtgaag aacaatttca ggatgtttgc aacccaattc cttagcgtac
     9361 tcaacagcac cctgagccat gtaacgcaac agcgtagcgt tggcatactg acgggcaccc
     9421 ttagatacct gaagaataac cggagacttt gtttcaactg cagccttgat gatagcctgc
     9481 atctgttcca tattgttgaa gttgaatgcc ggaatagcat atccaccttt gatagcctta
     9541 gcaaacatct ctcttgtgtt taccagtcct aaatctttgt aattaaccat tttgtttaaa
     9601 ttttattgtt agtgaattaa aattctacgc aaaagtaatc attatccttt aaagtaaaga
     9661 acttgagagg aataaaatat ccggctcatc ctaccaaatc cattctattt taaagctatt
     9721 ggcttcattt aacagattat tgtaatctct atattacaaa ctctttgcat ttatctctgc
     9781 cagccatact tttgccatct atacttctat caacaaaaaa gccggagaac atgtttgctc
     9841 tccggcatct gtttacacat tattatgtaa tactaatttt tcagatagat gatggtcggc
     9901 aaatggtcac tgtaaccgtt cagccaagtc ctgcccccat gcgtacgcaa gggggaacct
     9961 ttgtatttgc catcctgctg aatcagataa tcgcggatga aaacttcatt gtgatcatag
    10021 cgcaaccctt tcttagcctt cagcaacggt ttcgaaatga caatctggtc aaacaagttc
    10081 cacttgcccc gatagagcaa tgtccccact cccttgtctt ccagtgtctc ccaccaggga
    10141 ttgtagaatt cgcctttctt cacctgcttc ggatatttgc gtgcacccag cacctccatg
    10201 ctttcatcca tcgggtcgtc attcatatcc cccatcacga tgagtttcag cttcttgtcg
    10261 ctacgcatca gagagtcctt caaggccttt acctgcctgg ctgcatgcac acgcaccggt
    10321 gactttgccc cacgggaggg ccagtggttc actatcacgc agacacgctc tcccgccagt
    10381 tgtccgtcca caatcaggaa gccgcgcgtc aagtgcaccg tatccccctc aaaaggagta
    10441 gaaagcacca actttgagtg ggtaacgctg aactgcttcg ggtcgtacag caaggcacag
    10501 tcgatgcccc gtctgtccgg tccttcataa tgcacgaact cataattgga aatggccggc
    10561 tgcttcacga ggtcttccag cacccggctg ttctccgcct ctgccacacc gatgaatgcc
    10621 ggaccttccg gcactaaatc acgcgaaagg gaacccaaca ctttggaaag gttctgcagc
    10681 ttggactcat acttctttgc cgtccattgg taactgccgt cgggcaggaa ctcatagtca
    10741 ttcttacctg catcatgaat cgtatcaaac aagttctcaa gattgtagaa cgcaacacta
    10801 tacagtttcc gttccgcatt ttgtgccccc agcgttgcca cgcacagcca gaaagagcat
    10861 aagacaagta gtttcctcat aaattcacaa gattaagtcc tgcaaaaatc agaaataaaa
    10921 tgcgataaac ctactaaata aaaataaatc tgaatttatt ttgtagagtc tccaacttgc
    10981 actatctttg cgctctgaaa agaagaccat tacactattt attaccaaaa tagtaacaga
    11041 atataaattt ttaaaagaaa atatcaaaat gaaaaaagg
//
