LOCUS       gnlProkkaNBEHLMEO_216  12306 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NBEHLMEO_216.
ACCESSION   gnlProkkaNBEHLMEO_216
VERSION     gnlProkkaNBEHLMEO_216
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 10:51:01
            Original ID  :: gnl|Prokka|NBEHLMEO_216
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 43422
            Orig. end    :: 55728
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12306
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10354]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10354
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12306
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12306
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             146..325
                     /locus_tag="ctg216_44"
                     /transl_table=11
                     /translation="MKEQNAERLSEYEKAQIEFAKGKAEFLQGCGGCLMIPIIIIILLC
                     IVILIGLIASPFMD"
     CDS             363..977
                     /locus_tag="ctg216_45"
                     /transl_table=11
                     /translation="MKKIITSIFILMFYLGCSPSQKDVLFANASDEQIIEWGKQYVVHS
                     IEDSLKEGESYKIMEWILAEKKTSIPVEVWQMDNTYKKDSISECVKLLDTRGIFDELAF
                     IGNGDSAFVAFAVAYTIDEKNGNSSFLEKVFTLDKSGKVLDCSDYLSPSQKRKQIEENF
                     NRALEQMGPILIQTVKEGAAMAGKDTSNVTSITINGKTYSE"
     CDS             996..2885
                     /locus_tag="ctg216_46"
                     /transl_table=11
                     /translation="MKTNERILRINSVLQNHFIKHPQSGMVLAKEFMPLFIENGIFNKD
                     YREGLPIRKVLRALDTENSLDKIPYVHAERKSKITNWYFRPLLLSLVIFMGMLSSCSFK
                     SNTDFPEVTHVAFQKEKHGKWGMVGVNGNILFENKFDKRPSYAVNGVFRIQDYDTNQYL
                     YYSATPTPKLIGTPKGYKQGGICSEGIIPVVSADERIHYLTETGETAFYLLPYQGKEFL
                     CVSPFFTEQRAWFRLENRKCGYIDPQGNVVIEPIYDNAFPFHEGKAIVYNKEADKWLVI
                     DPNGKELFEASSNGYQQYSYTFFENGYCLIENFLLNEKGEKAQRFPSNIYSISPFIDNV
                     ALFQDSKTGLWGQLNIEGESIGEPKYSRALGIIDDWIYVADTIANLRDEWDNQYMNVYA
                     INSKGEIKNKIENVSCFYPLSQYAIMAENEKYYFADKKGNPIDNNSYYKISVPPFTDAP
                     SYSPFWSSLIAPHSMSDYDAWGVATDYIDEKKTLASIFDKLTSDGIDSLKIGQTISRIM
                     DLYNIKQMPTKGMVDLHNRDWGINQVFATYSVGILHECKCAIVIKVKINVSASPIGDNP
                     KKLFDAIPQYLTETLGLKREDETLYRSEDACYDIVYYEGEDSFFLMSKAITEK"
     CDS             2991..3209
                     /locus_tag="ctg216_47"
                     /transl_table=11
                     /translation="MDLGRIELPSKRGNHMLSTCLSLPKIFEHKQDQSHQLMPYPLKFR
                     KSYEEKLKLFPILLCHFIKRFGTRAFE"
     CDS             4816..7644
                     /locus_tag="ctg216_48"
                     /transl_table=11
                     /translation="MKNLIALTLLLGGNTLLCAQKPAKTPATYKPVKSEMYRKGWIDFN
                     KNGVKDVYEDPSAPLEARIENLLQQMTLDEKTCQMVTLYGYKRVLKDDLPTPEWKELLW
                     KDGIGAIDEHLNGFQQWGLPPSDNAYVWPASRHAWALNEVQRFFVEDTRLGIPVDFTNE
                     GIRGVESYRATNFPTQLGLGHTWNRELIRQVGLITGREARMLGYTNVYAPILDVGRDQR
                     WGRYEEVYGESPYLVAELGIEMVRGLQHNHQVAATGKHFAAYSNNKGAREGMARVDPQM
                     SPREVENIHIYPFKRVIWEAGMLGVMSSYNDYDGIPVQGSYYWLTTRLRGEMGFRGYVV
                     SDSDAVEYLYTKHGTAKDMKEAVRQSVEAGLNVRCTFRSPDSFVLPLRELVKEGGLSEE
                     VINDRVRDILRVKFLIGLFDAPYQTDLAGADREVEKEENEAIALQASRESIVLLKNAGE
                     LLPLDINSTKKIAVCGPNANEEGYALTHYGPLAVEVTTVLEGIQEKTKGKAEVLYTKGC
                     DLVDAHWPESEIIDDPLTDDEQAEIDKAVENARQADVAVVVLGGGQRTCGENKSRTSLD
                     LPGRQLQLLQAIQATGKPVVLILINGRPLSINWADKFVPAILEAWYPGSKGGTALADIL
                     FGDYNPGGKLTVTFPKTVGQIPFNFPCKPSSQIDGGKNPGPTGNMSRINGALYPFGYGL
                     SYTTFEYSDLDITPRVITPNESATVRLKVTNTGKRAGDEVVQLYIRDVLSSITTYEKNL
                     AGFQRIHLEPGEAQELSFTIDRKHLELLDADMKWVVEPGDFVLMAGASSEDIRLNGTLT
                     VEDYQTRAKAIEAPKPAKRVSASTNPEDAENVLDEKINTAWQGNKGDYITFALKNGAKV
                     DKVAIAFTRDNNLPATFEIQLSGGGGQFLTVYSGTVSEYGKLISYPFKGTTASDLRIVL
                     NDDRVSIAEVKF"
     CDS             7746..8873
                     /locus_tag="ctg216_49"
                     /transl_table=11
                     /translation="MKTLLFCMLGLGLTACGSSPKGTNGDQDELAMLIGTYTNGSSKGI
                     YTFRFNQETGTAVPLSSAALPNPSYLVPSEDGEFVYAVSEMNDSTAALSSLAFDRETGE
                     LRLLNTVPTFGADPCYVATNGREVLTANYSGGTMSVFPLQKDGTLAPADTLFQGSATGP
                     DAIRQATPHIHCTVFSPDGKYIFATDFSADRILRFVMHPDNPIPHASLEAVGIEADSGP
                     RHLTFSPNGKFAYLITELSGKVIAFSYDDGRLEQIQTITADTVAARGSADIHLSPDGKY
                     LYASNRLKEDGIAIFAVNPENGTLAKVGYQPTGIHPRNFNITPNGKYLLAACRDSNVIQ
                     VYKRNEVTGLLEDTHQDIVVDMPVCVQFVSSVNNL"
     CDS             8935..9993
                     /locus_tag="ctg216_50"
                     /transl_table=11
                     /translation="MYIMKKNILMLSALFLSITAMAQTDVTTGVMRGKDYGVTYMLPKT
                     EIEIVLQATKHTYTPGEFCRYADRYLRLNNVSAEPEEFWTLDKIETRIAGVPDKDNVYF
                     VKMKDKTVAPLMELTEDGIVRSINIPFSGKPAAKTPEAKATESSIDPRSFLTEEILMSN
                     SSAKMAELVAKEIYSIRESKNALLRGEADNMPKDGAQLKLMLDNLNQQETAMTEMFSGK
                     IKKEPKTFTIRLTPKEMKDEVAFRFSRKLGVVANNDLAGEPYYISVTDLKSPDVSATEE
                     GKKKVDGVAYNLPGKAQVTLMYNNKKLFDDQLPITQFGTVEYLAPVLFNKNSTIKVLFD
                     TATGGLIKVDRE"
     CDS             complement(10001..10354)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg216_51"
                     /sec_met_domain="PqqD_RRE (E-value: 4.8e-10, bitscore:
                     30.9, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 8.5e-17, bitscore: 53.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMEIPEGKVSLLDAVPVRCGHITTEWEGECAVLAYPRFKYEWMRR
                     FLLPKGMSPDIHVRLEEHGTAVWNLIDGHRTVREIISLLARHFGEEENYIPRVTAYVMQ
                     LRKDGFIQLTIRN"
     CDS             complement(10374..11765)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 101.4; E-value: 7.2e-31)"
                     /gene_kind="transport"
                     /locus_tag="ctg216_52"
                     /transl_table=11
                     /translation="MTEQLKLKLNDSKATRWGALVIVAFTMMAAYYVNDVVAPLKTMLE
                     TDLAWSSTDFGFFTGGYSFLNVFFLMLIWGGLILDRFGIRFTGKLATILMVGGTALEYY
                     AMTGLAGADATLFGINEIFGYKTGVFVAFAGYSIFGVGAEVAGITVSKIIAKWFKGKEL
                     ATAMGVQVALARIGSQAGYAVAIPLARAFGISTPVLLGLVLLLGGMIAFFVFAVMDKKL
                     DKQMEAAAIAAGTEDEEEKFSFKDVKNILVNPGFWLIALLCVLFYSCVFPFQKFASELM
                     IIKYGINENVAGTFAGLPALGALILTPVFGGFIDKRGKSASIMLLGSAMLICVHFIYAI
                     PDINYWLVAIVLMIILGIAFSLVPSAMWPAVAKIFPVSQLGTAYALIFFIQNIGLWGIP
                     TLIGWVLDAYCISGKKPDGTNMYDYTVPMCIFTGIACLSLIVALLLKKADKKYGYKLEE
                     PNIQK"
     CDS             complement(11919..12305)
                     /locus_tag="ctg216_53"
                     /transl_table=11
                     /translation="MLLLVILMLIASVLMCFIVLIQNSKGGGLASGFSSSNQIMGVRKT
                     TDFLEKATWTLAAVMVVFSIVSAYTIPSSTGKGGDVILEQAQQEEKTNPYNMPVGTEAP
                     QSEAPAATTPAETPAPAAEAPAAE"
ORIGIN
        1 tagggctaaa aacagttatg gcggttacgt ggtggaagag aaactttttg tattggattc
       61 tgacgggaat gttataaaag ttgtagatga catgaatgaa gtcattaatg gttattgata
      121 taaacaatga acaaacaatg aagttatgaa ggagcaaaat gctgaaagac tttctgaata
      181 tgagaaagcc caaatagagt ttgcaaaagg taaagcggag tttctacaag gatgtggcgg
      241 ttgcctgatg atcccaatca tcattatcat tctactttgt atagtaattt taataggtct
      301 aattgcttct ccttttatgg attaatcaaa aaatttaatt ctaacttaaa taatatggca
      361 ttatgaaaaa aattattact tctattttca ttttgatgtt ttatcttggt tgttcaccat
      421 cacagaagga tgtactgttt gcaaacgctt ccgatgaaca aatcatagaa tggggtaaac
      481 aatacgtagt ccattccatt gaggatagtt taaaagaagg agaaagttac aaaataatgg
      541 aatggatttt ggcagaaaaa aagacaagta ttcccgttga ggtatggcaa atggataata
      601 catataaaaa agattcaata tcagaatgcg tcaagctatt agatacacga ggtattttcg
      661 atgaactcgc atttatagga aatggtgata gcgcatttgt agccttcgct gttgcatata
      721 caatagatga aaagaatggg aatagttcat tcttagaaaa agtttttacc ctcgataaaa
      781 gtggtaaagt gttggattgt agcgattacc tcagcccttc tcaaaagaga aaacaaatag
      841 aagaaaattt taacagagct ttggaacaga tggggcctat tctgattcag acggtaaagg
      901 aaggtgcagc tatggctggt aaagatacaa gcaatgtaac aagtataacg attaatggaa
      961 agacatattc cgaataattt ataatattac gtattatgaa gacaaatgaa cgtattttaa
     1021 gaatcaacag tgttttgcaa aatcatttta taaaacatcc tcaaagcgga atggttcttg
     1081 caaaagagtt tatgcctctt ttcatagaga atggcatttt caataaagat tatagggaag
     1141 gtttgcccat tcgaaaagtt ctgagagctt tggatactga aaattcattg gacaaaatcc
     1201 cctatgttca tgccgaaagg aaatctaaaa taaccaattg gtattttcgt cctttgcttt
     1261 tatcgcttgt gatatttatg ggtatgcttt cgagttgttc atttaagtca aataccgatt
     1321 tccctgaagt gacccatgta gctttccaaa aagaaaaaca tgggaaatgg ggcatggttg
     1381 gagttaatgg aaacatcttg tttgaaaaca aatttgataa aagaccgtct tatgcagtaa
     1441 atggagtgtt tagaattcag gattatgata caaatcaata tctttactat tccgcaactc
     1501 caactcctaa attgatagga actccaaaag gttataagca aggaggcata tgtagcgaag
     1561 gaataattcc tgttgtttct gcagatgaac gtattcacta tctaacagaa acgggagaaa
     1621 ctgcttttta tttgcttccg tatcagggga aagaattctt atgtgtatct ccgttcttta
     1681 cggagcaacg tgcttggttt cggttagaaa atcgtaaatg cggatatata gatccacaag
     1741 gcaatgttgt gatagaacct atttatgata acgctttccc tttccatgaa ggaaaagcta
     1801 ttgtatataa caaagaagct gacaaatggt tagttatcga ccccaatgga aaagagttat
     1861 ttgaagccag ttccaatggg taccaacaat attcatacac cttttttgaa aacggatatt
     1921 gtttaataga aaacttctta ctcaatgaaa aaggcgaaaa agcacagaga ttcccttcta
     1981 acatttacag tatttcacct ttcattgaca atgttgcctt atttcaagac agtaaaactg
     2041 gattatgggg acaacttaac atagaaggag aaagtatcgg agaacctaaa tattcgcgag
     2101 ctttaggcat tatagacgat tggatatatg ttgctgatac aattgccaat ttaagagatg
     2161 aatgggacaa tcaatatatg aatgtatatg caataaactc taaaggtgaa attaaaaata
     2221 aaatagaaaa cgtttcatgt ttttatccat tatcccaata tgctataatg gcagaaaatg
     2281 agaaatatta ctttgctgac aaaaaaggga atccgataga caacaactct tattacaaaa
     2341 tttcagttcc cccatttaca gatgctccca gttattcacc cttttggtct tctttaatag
     2401 cacctcattc catgtctgat tatgatgctt ggggagttgc taccgattat atagatgaaa
     2461 agaaaacatt ggcatcaata ttcgataagc taacatccga cggcattgac agcttaaaaa
     2521 ttggtcaaac tatttcaaga attatggatt tatataatat aaagcaaatg ccaacaaaag
     2581 gaatggttga cttacataat agagattggg gtataaatca agtctttgcg acatattccg
     2641 ttggtattct tcatgaatgt aagtgtgcaa ttgtgattaa agtaaagatt aatgtgagtg
     2701 cttctccgat aggtgataat ccaaagaaat tgtttgatgc tataccacaa tatcttacag
     2761 aaactttggg attaaaaagg gaagatgaaa ccctttatcg atctgaagat gcttgttatg
     2821 atattgttta ttatgaagga gaggattcat tctttttaat gtctaaagcg ataacagaga
     2881 aatagttaag aaacattcat ataaatcgaa cacttaaaaa tattcccgta cagaacatca
     2941 aattctgtac gggaatactt ttatacataa aaaataatta tctaagtatc gtggacctgg
     3001 ggagaatcga actcccgtcc aaacgaggaa accatatgct ttctacatgc ttatctttgc
     3061 ctaaaatttt cgaacataag caagaccaaa gccaccaact tatgccttat cctctaaaat
     3121 ttcgtaagag ttacgaggaa aaactcaaac tattcccgat tttactgtgc cactttatca
     3181 aacgcttcgg aacaagagct tttgagtgac atctcgtttc taccactttg gcggaaataa
     3241 agctaatcta ctatacttcg attaagcagc gagagcataa ttttcgttgc cagataaaat
     3301 tttgataact gatatttaag tggaaattac cgacccactg catgcttaca taccattcca
     3361 actcgctgtc aattccagtc aagccctaat gatgtttcaa agataggaaa tcgccttgat
     3421 aagaacaaac aaaatgataa aaattaaaat agaatatcac aaatcatcac aatagttaat
     3481 ttatttaaga aaggcagata gcttttgata taaagaatga taatcagact atcatttttt
     3541 atttcagggt gcattttggg gtgcaaacaa tataagcacc taattatcaa tatcatttgt
     3601 ggagctggag ggaatcgaac cctcgtccaa acgaggaaat cataagcttt ctacatgctt
     3661 atctttgcct aaattttcgt gcagcggcag aaccaaagcc atcaaccgtt gccttatcct
     3721 ctaaattttc acccgcgcca cgaggctgac acgaactatc cccgatttga ctgcaccact
     3781 ttatcggaat gcttcggagc aacagcttcc gagtgatgtc acgtcccagc acctggtgcc
     3841 gggattaagc ttcaatctac tatacttcga ttaagcagcg agagcgtaac gagtttcgcc
     3901 agataaaatt ttgaggactg agattaaagt gcaaatcaac gacgcactgc atgcttactt
     3961 accatttctg cccgctgtca aatccagtca accccatgac tttgtaacgg tctgaaattt
     4021 aaaagattgc gtaactcatt gctaagtagg gagggtgaaa aagggataaa tgctacttta
     4081 tttttcatcc tctaccgctt tctttggccc aaagatacat attcttttat tagcaatcac
     4141 catatattta caaatattag ctaatactga cttttcgtga taaaaacaat aatcttccat
     4201 acatagaata tgtgcacccc attgtcatca atgttcaaac agctaccaaa gccagtatcc
     4261 gttgacggaa ttaccccctg caagagggaa tatctatctt ctgtaatgga tatttgcaca
     4321 aaagagatgg gaagttaacg gaaaaagtct ctgaagttaa ctgaaaaacc ggaaagaatt
     4381 aaggaagcaa tctatcccaa actttggttt ttccataccc aaccttggga tgtctaaacc
     4441 aaggttgggt ttagacatcc caaggttgaa aagaaagttc ttccgtacaa gcaacaattc
     4501 cgccaacaga ttcctattat ataaatacac cctcgtttaa cagatgtagc cgtaatactt
     4561 gtatacaccg cgattgcatc tacttttcag gttattatag tgttctctct ttctttttaa
     4621 aagtgaatga tatgtttcgt ctaataatga tttgaattcc ccggtagcgt cttggaggat
     4681 atttttagta agaggaagac ccttcggaca ataaaagccg atacttcgga ctattttatc
     4741 cctttatttc acacattagc cgtatttttg tcaacaaaag aaacaataat aaccaagaga
     4801 tttttagaac atatcatgaa gaaccttatt gccctaaccc tgctgcttgg aggaaacaca
     4861 ctgctctgcg cacaaaagcc tgccaaaaca ccggcaacct acaagccggt gaaaagtgaa
     4921 atgtaccgca aaggttggat agacttcaac aaaaacggag tgaaagacgt gtacgaagac
     4981 ccctccgccc cgctcgaagc acgcatcgaa aacctgctgc aacagatgac gctggacgaa
     5041 aagacctgcc aaatggtcac cctctacggc tacaaacgcg tactgaaaga cgacctcccc
     5101 acccccgaat ggaaagagct gctctggaaa gacggcatcg gcgccatcga cgaacacctg
     5161 aacggcttcc agcaatgggg gctgcctccc tcggacaatg cctacgtctg gcccgcctcg
     5221 cgccacgcct gggcactgaa cgaggtgcaa cggttctttg tggaagatac ccgtctcggc
     5281 atccccgtag actttaccaa cgaaggcata cgcggcgtgg aaagctaccg cgccaccaac
     5341 ttccccaccc aactgggact gggacatacc tggaaccgtg aactgattcg ccaagtagga
     5401 ctcatcaccg gacgcgaagc ccgcatgctg ggctacacca acgtctacgc ccccatcctc
     5461 gacgtaggac gcgaccagcg ctggggacgc tacgaagaag tttacggcga atctccctac
     5521 ctcgtagccg aactgggcat cgaaatggtg cgcggcttgc agcacaacca ccaagtggcc
     5581 gccaccggca agcattttgc cgcttacagt aacaacaaag gcgcccgcga aggcatggca
     5641 cgcgtggacc cgcaaatgtc gccgcgcgaa gtggaaaaca tacacatcta ccccttcaaa
     5701 cgcgtcatct gggaagccgg catgctgggc gtaatgagtt cgtacaacga ttacgacggc
     5761 atccccgtgc agggcagcta ctactggctc accacccgcc tgcgtggcga aatgggattc
     5821 cgtggctacg tcgtatccga cagtgacgcc gtagaatacc tctacaccaa gcacggcacc
     5881 gccaaagaca tgaaagaagc cgtccgccaa agcgtggaag ccgggctgaa cgtacgctgt
     5941 accttccgct cgcccgactc cttcgtcctt cccctccgcg aactggtgaa ggaaggcgga
     6001 ctgagcgaag aagtcattaa cgaccgtgtg cgcgacatcc tccgggtaaa gttcctcatc
     6061 ggtctgttcg atgcccccta ccagacagac cttgccggtg ccgaccgtga agtggaaaaa
     6121 gaagagaacg aagccatcgc cttgcaggca tcccgcgagt ccatcgttct gctgaagaat
     6181 gccggtgagc tgttgccctt agacatcaac tccaccaaga agattgccgt ctgtggtccc
     6241 aatgccaacg aagaaggcta cgcgctgacc cattacggcc cccttgccgt agaggtgacc
     6301 actgtactgg aaggcattca agaaaagaca aaaggcaagg cagaggtgct ctacaccaaa
     6361 ggctgcgacc tagtggatgc ccactggccc gaaagtgaaa tcatagacga tcctctgacc
     6421 gacgacgagc aagccgagat agacaaagcc gtagaaaatg cccgccaagc tgatgttgcc
     6481 gtcgtagtat tgggcggcgg acaacgcacc tgcggcgaaa acaaatcgcg caccagcctc
     6541 gacctgcccg gccggcagtt gcaactgctt caagccatac aagccacggg caagcccgtc
     6601 gtactgatac tcatcaacgg acgcccgctc tccatcaact gggcagacaa gttcgtcccc
     6661 gctatcctcg aagcctggta tcccggctcc aaaggcggaa cagccctggc cgacatcctc
     6721 ttcggcgact acaaccccgg tggaaagctg acggtgacct tccccaagac cgtagggcaa
     6781 atccccttca acttcccctg caaaccttct tcacagatag acggcggtaa gaatccggga
     6841 cctacgggca acatgtcacg catcaacgga gcactctacc ccttcggtta cggcttgagc
     6901 tacaccacct tcgagtactc cgacctcgac atcacccccc gagtcatcac cccgaacgag
     6961 tctgccaccg tccgcctgaa ggtgaccaac accggcaaac gtgccggaga tgaagtagtg
     7021 cagctctata tccgcgacgt actgagcagc atcaccacct acgaaaagaa tcttgcaggc
     7081 ttccagcgca tccacctcga accgggcgaa gcccaggagc tgtccttcac catcgaccgc
     7141 aagcacctgg agcttctgga cgccgacatg aaatgggtgg tggaacccgg cgacttcgtg
     7201 ctcatggccg gcgcctcttc cgaagacatc cgcctgaacg gaacgctgac cgtagaagac
     7261 taccagaccc gtgccaaagc cattgaagcc ccaaaaccag caaagcgtgt gagtgccagc
     7321 accaacccag aggatgccga aaacgtgctc gacgaaaaaa tcaataccgc atggcaagga
     7381 aataagggag attatattac ctttgcctta aagaacggag ccaaggtaga taaagttgcc
     7441 attgccttta cacgtgacaa caacctgccg gcaaccttcg aaatccagct ctcgggcggt
     7501 ggcggacagt tcctcaccgt atattcgggc accgtcagcg aatacggcaa actgatttcc
     7561 tatccgttca aaggcactac cgccagcgac ctccgcatcg tgctgaacga tgaccgcgtc
     7621 agtattgccg aagttaaatt ttaatgtgct aatgtgccaa tatgctaatg taccaatgac
     7681 catgcagcat atacagcgca gccaattagc acattagcat attggcacat taacacatta
     7741 aattaatgaa aacacttctt ttctgtatgc tcggattagg tttgacagca tgtggctctt
     7801 ctccaaaggg cactaacggt gaccaggacg aactcgccat gctaataggt acttacacga
     7861 atggctcaag caagggtatc tataccttcc gctttaatca ggagacggga acagccgttc
     7921 cgctcagttc agcggcattg cccaatccct cctacctcgt cccctcggaa gatggcgaat
     7981 ttgtctatgc cgtcagtgaa atgaacgaca gcacagcagc cctcagctcc cttgccttcg
     8041 accgggaaac gggagaactg cgcctgctga acaccgttcc caccttcggc gccgacccct
     8101 gctacgtggc caccaatggc cgggaagtgt tgactgccaa ctacagcggt ggaaccatgt
     8161 ccgtctttcc tttacagaaa gacggcactt tggctcctgc agacacgctc tttcaaggct
     8221 ctgccaccgg tcccgacgcc atacggcaag ccactcccca catccattgc acggtctttt
     8281 caccggacgg aaagtatatc ttcgccaccg acttcagtgc cgaccgcatc ctgcgctttg
     8341 tgatgcaccc cgacaaccct attcctcatg cttctctgga agccgttggc attgaggcag
     8401 attccggccc gcgccatctg acattcagcc ctaacgggaa gtttgcctat ctcatcaccg
     8461 aactgtccgg taaggtcatt gccttcagtt acgacgacgg ccgcctggaa cagatacaga
     8521 ctatcacagc cgacaccgta gccgcccgtg gaagtgcaga catccacctc agtccggatg
     8581 ggaaatacct ctacgccagc aaccgtctga aagaagacgg catcgccatc tttgccgtga
     8641 atcccgaaaa tgggaccttg gcaaaggtag gttatcagcc caccggcatc catccccgca
     8701 acttcaacat cacgcccaac ggtaaatact tgcttgccgc ctgccgcgac agcaatgtca
     8761 ttcaggtata caaacgaaac gaagttaccg gactcttgga agatactcat caggacattg
     8821 tagtcgacat gccggtttgc gtacagttcg tcagctctgt taataattta taaagcaata
     8881 tttagcaaag ataacttcat taactttgtc ccttagctaa atcagtctaa acgaatgtac
     8941 attatgaaga agaatatatt gatgctctca gctctgttct tgtctatcac tgccatggcg
     9001 caaacagacg taaccaccgg tgtgatgcgt ggcaaagact acggagtgac ttatatgttg
     9061 cccaaaacag aaatagaaat cgtattgcaa gccaccaagc atacctacac tcccggagaa
     9121 ttttgcagat atgccgaccg ctatctgcgt ctcaacaacg tgtctgccga acccgaggag
     9181 ttctggacac tggataagat agaaacccgc atagccggtg taccggataa ggacaacgtc
     9241 tatttcgtga agatgaaaga caagaccgta gcacccctta tggagcttac cgaagacgga
     9301 attgtccgct ccatcaacat tccgttcagc ggtaagcctg ctgccaagac gcccgaagcc
     9361 aaagccaccg aaagcagcat tgacccacgc agttttctga cggaagaaat actgatgtcc
     9421 aactccagtg ccaagatggc cgagctggtg gctaaggaaa tatacagcat ccgcgaaagc
     9481 aagaatgccc tcctgcgcgg cgaagcagac aatatgccca aggacggcgc ccaactcaag
     9541 ctgatgcttg acaatctgaa ccagcaggaa acggctatga cggaaatgtt ctcgggcaaa
     9601 ataaagaaag aacccaagac attcaccatc cggctgacgc ctaaagagat gaaagatgag
     9661 gtggctttcc gtttttcccg aaagctggga gtggtggcca ataatgacct tgccggtgaa
     9721 ccgtattata tcagcgtcac cgacctcaaa agtcccgatg tatctgccac cgaggaaggc
     9781 aaaaagaaag tggacggtgt agcctataac cttccgggca aggcacaagt gacattgatg
     9841 tataacaata agaaattgtt tgacgaccaa cttcccatta cccaattcgg caccgtagaa
     9901 tacctcgcac cggtactgtt caacaagaat tctaccatca aagtgctgtt tgatacggca
     9961 acgggaggat tgataaaagt ggatagggaa taaaggaatt ctaattccgg attgtcaact
    10021 ggataaatcc atccttacgc aactgcatta cgtaggcggt gacccgggga atataattct
    10081 cttcctcccc aaagtgcctg gcaagtagag agatgatttc gcgcacggta cgatgtccat
    10141 ctatcagatt ccagacagct gtaccgtgtt cttccagcct cacatggatg tcaggagaca
    10201 tccccttcgg caataaaaaa cgacgcatcc attcgtattt aaaccgtggg taggcgagta
    10261 cggcgcactc accttcccat tcggttgtta tatgtccaca gcggaccgga acagcgtcca
    10321 acagacttac ttttccttcg ggtatttcca tcatacggta tccgcttttc ctattatttc
    10381 tgaatattag gctcttccag cttataacca tacttcttgt ctgccttctt cagcagtaga
    10441 gccactataa gggacaagca ggcaataccg gtaaaaatgc acataggcac cgtatagtca
    10501 tacatattcg ttccatctgg tttcttgccg gatatacaat aggcatcaag cacccaccct
    10561 atcaatgtag gaatacccca aagaccgata ttctggataa agaaaatcaa tgcgtatgcc
    10621 gtacccaact ggcttaccgg gaatatcttg gccacagccg gccacatggc agaaggtacc
    10681 agcgagaaag cgatacccaa aattatcatc agcacaatag ctaccagcca atagtttata
    10741 tcgggaatag cataaatgaa atgcacacat atcagcatgg ccgagcccag cagcatgata
    10801 gatgcggact tgccccgctt gtcaatgaaa ccaccaaaga ccggagtcag aatcagcgct
    10861 cccaatgccg gaagtccggc aaatgtaccg gccacattct cattgatacc gtatttgata
    10921 atcatcaact cggaagcaaa cttctggaat gggaatacac aagagtagaa caatacacac
    10981 agcaatgcta tcagccagaa accgggattg accagaatat tcttcacatc cttaaaagag
    11041 aacttctctt cctcatcttc cgtaccggca gcaatggcag cagcttccat ctgtttgtcc
    11101 agcttcttgt ccatcactgc aaagacgaag aaagcaatca taccgcccaa caacagaacc
    11161 aaacccaaca acaccggtgt ggaaataccg aaagcgcggg ccaaaggaat ggctacggca
    11221 taaccggctt gcgaaccgat acgtgctaaa gcgacttgta cccccatagc cgtggcaagc
    11281 tctttcccct taaaccactt ggctatgatt ttggaaactg taataccggc gacctccgct
    11341 cctactccaa aaatggaata accggcaaaa gcaacaaaca cacccgtttt atagccaaat
    11401 atttcattga ttccgaataa agtcgcgtcg gcaccggcaa gtcccgtcat tgcatagtat
    11461 tcaagtgctg taccacctac catcaggata gttgccagct ttccggtgaa acggatacca
    11521 aagcggtcga ggattaatcc tccccaaatc aacatcagga aaaaaacatt cagaaaacta
    11581 taaccaccgg taaagaatcc gaaatcggta ctcgaccaag ccaagtccgt ttccaacatt
    11641 gtcttcaacg gtgctaccac gtcgtttaca taataagctg ccatcatcgt gaaggcaaca
    11701 atcaccaatg ccccccaacg ggtagccttg gaatcattca atttaagttt gagttgttct
    11761 gtcattgtac tatttggatt tcaatttatt aatcagattg cataaattgc tgacaaaggt
    11821 aaataaatac ttcatcaaaa cgaaaaaagg ctgacacctt ttcagtatca acctttctct
    11881 tatttttcca agcgggagtc atccgcaata tccttatctt attctgctgc aggggcttct
    11941 gctgcaggag caggagtttc agccggagtt gtagctgcag gggcctccga ttgcggagct
    12001 tctgtaccta cgggcatgtt ataaggatta gttttttctt cttgttgcgc ctgttccaga
    12061 atcacatcac cgcccttgcc tgtggaagaa ggaatagtgt aagcagaaac aatactgaag
    12121 actaccatga cagctgccag agtccaggtt gctttttcca aaaagtccgt agtcttgcgc
    12181 acacccataa tttggttgga tgatgaaaag cctgatgcca gaccacctcc tttagaattt
    12241 tgaatcaata caatgaagca catcagcaca gatgcaatca gcattaagat aactaataat
    12301 aaatac
//
