LOCUS       c00220_gnlPro..        13594 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NBEHLMEO_220.
ACCESSION   c00220_gnlPro..
VERSION     c00220_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 08:51:45
            Original ID  :: gnl|Prokka|NBEHLMEO_220
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13594
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13594
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[638:3594]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      639..3594
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13594
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13594
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             2..223
                     /locus_tag="ctg220_1"
                     /transl_table=11
                     /translation="ERQGFEPRVPRSTTVFKTAAIDHSATSPKLLFQKYFSFKAVQRYK
                     SFFILQTFLHKNRAIIPKFLFIPTTERT"
     CDS             639..2867
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg220_2"
                     /sec_met_domain="Gly_radical (E-value: 2.7e-46, bitscore:
                     148.2, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1170.4, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFTNGLWNKEINVSDFVSKNIAPYTGDASFLQGPTERTKR
                     IWDICLKALEEERNNNGVRSLDNTTVSTITSHKAGYIDKDNELIVGLQTDELLKRSIKP
                     FGGINVVAKACRENGVEVDDKVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGIDRLIEAKQEDLRNLTGPMTEARIRLREEVAEQIKALKDIK
                     VMGEYYGLDLSHPATSAQEAVQWVYMAYLAAIKEQDGAAMSLGNVSSFLDIFIEYDLAH
                     GKIDETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTEAIGGRFNDGRVKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKDFCAKVSVDTSSIQYENDNLMREVRNC
                     DDYGIACCVSYQAIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKGIPVLTGETL
                     KFEEVMANYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMAFIDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAKVTARRNEIGLTEGFDTEGSFPCFGNNDDRVDHLGVDLVYYFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGPTPEERVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLEDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             2869..3594
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74.8;
                     E-value: 2.8e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg220_3"
                     /sec_met_domain="Radical_SAM (E-value: 1.4e-30, bitscore:
                     98.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCPFRCLYCANPDTIDVKGG
                     TPTTPEEILQMAISQKAFFGKKGGITFSGGEPTLQAEALIPLFKELKANDIHICLDSNG
                     GIWNEKVEELFSLTDLVLLDIKQFNPERHRTLTGRSNEQTLRTAAWLEEHEHPFWLRYV
                     LVPGYSDSEEDTRLLGESLGKYQQIQRVEILPYHRLGVHKYEAMGWDYKLKEVKENTPE
                     QLERAEKLFKEYFTNVITN"
     CDS             complement(3663..5867)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fn3-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3_C"
                     /gene_functions="other (smcogs) SMCOG1041:Fibronectin type
                     III-like domain (Score: 84.6; E-value: 1.3e-26)"
                     /gene_kind="other"
                     /locus_tag="ctg220_4"
                     /sec_met_domain="Fn3-like (E-value: 1e-26, bitscore: 84.6,
                     seeds: 729, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3 (E-value: 2.3e-75, bitscore:
                     245.5, seeds: 11, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3_C (E-value: 3.7e-52,
                     bitscore: 168.9, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIIILMVCLWGLGNTFTSAQTTEKEKFISSLMKQMTLDEKIGQ
                     LAQCTYRGNFTGPDGGNIPKEEYVRQGRIGSMLNVIGVKDIRRYQELALQSRLRIPLIF
                     GLDVIHGYRTGFPLPLAEAASFDLAMIEEAARYNALESAADGLNWVFAPMVDISWDARW
                     GRVMEGAGEDPYYGSRVAEARVRGLQGDDLADTTTVMACMKHFAGYGAPIAGKEYNSVD
                     MSMGHFANFYMPPYKAAIKAGAATVMSAFNDFNNIPCTANDFLLNRLLREQWGFKGFVV
                     SDYNSVEELVNHRYAADKKDAAAKALNAGLDMEMVSTCYLTYLKELVQEGKVKESVLDD
                     AVRRILEKKYELGLFEDPFRYCNPERAARILNAPEVRNASLRMAERSVVLLENRESVLP
                     LTAQTRKIALIGGLSKSQYDMAGAWAATTDRNKVVTLYDALVRKGLEVNYAEGYDMKSN
                     QLTGLQEALQAAEASDVIVVAVGERFGQSGEKASKVNIAIPEGQQKLVSELAKTGKPVI
                     ALVMCGRPVIFNEIREHADAVLCTWWLGSEAGNAICNVLWGEYNPSAKLPMTFPAHVGQ
                     IPIYYQNKSTGRPTALKQTYKASYIDASTEPAYPFGYGLSYTDFGYSDLKLLPGKAAGV
                     HTEVSVKVTNTGKCAGEEVVQLYVQDKVASVTRPIKELKGFRKIHLNVGESKTVAFQIT
                     DDALGFYDNEMNYMVEPGDFVFMVGGSSDDVQQITYNLKE"
     CDS             complement(5898..8360)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fn3-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3_C"
                     /gene_functions="other (smcogs) SMCOG1041:Fibronectin type
                     III-like domain (Score: 78; E-value: 1.5e-24)"
                     /gene_kind="other"
                     /locus_tag="ctg220_5"
                     /sec_met_domain="Fn3-like (E-value: 1.1e-24, bitscore:
                     78.0, seeds: 729, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3 (E-value: 4e-56, bitscore:
                     182.3, seeds: 11, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3_C (E-value: 1e-50, bitscore:
                     164.2, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKKKVALSGLLLCCAITAKAQVCITPQVEQRARELVSQMTLEE
                     KIDYISGPKSFYIRAVPRLGIPEIRMADGPQGIRNNTQSTLYPCGILSASTWNRKLARE
                     LGHGLARDAKARGVSILLGPGVNIYRSPLCGRNYEYFGEDPYLTGETAKEYILGVQEEG
                     VMATVKHFAANNQEWSRHHASSDVDERTLQEIYFPAFRKAVQEAGVGAVMDSYNPLNGV
                     HATENSWLNIDVLRKQWGFKGILMSDWTSVYSGVGAANGGLDLEMPVGKFMTREILIPA
                     IENGIVREETIDAKVRHILQTLIAFGALDTPREDKSIDKDNAQSKEIALDLAREGVVLL
                     KNDNGTLPYRNGRTLVIGPNADIIPTGGGSGFVTPYSVVSLYDGMVQLKGGRQIELLSD
                     SLLYKDMSQQIYTDDSFTQNGFKSEYYNTRNLTGELFQAVIEPAIDYAWKYGAPFDGMP
                     VDQFSARWTGVYKADKDGTVKFQLAGDDGYRLFVNDKLITGDWGNHSFSTRSAFMQVST
                     GEIYRLRIEYFDNVGEATVSFQAGMMDEERLASSLKHARNVIVCAGFNSSTEGEGFDRP
                     FALSYGQEYLINKVASLHDNVTVVVNAGGGIDFRNWGQNVQAILMAWYPGQEGGKALAE
                     IITGKLSPSGKLPVSIEEKWEDNPVYGNYYDNRNVPHKRVQYAEGVFVGYRGYDRNGKQ
                     PLYPFGYGLSYSSFEYSNLSVEKTGGNRVTVSFDIKNTGKMDAAEAAQVYVRDVECSVP
                     RPLKELKGYDKVYLKKGETKRIRILLDEEAFAYYDVESHRFVVEKGTFEILAGPSSADL
                     PLKATVVL"
     CDS             complement(8537..9037)
                     /locus_tag="ctg220_6"
                     /transl_table=11
                     /translation="MPYLQRREKKIADIDHKQPLSFGVSVRKNLAKGFSVESGLTYTYL
                     ASDVRYEGSSEKISQKLHYIGIPVRANWNFVDTKNFTMYVSAGGAIEKCVYGKIGTESE
                     TVKPVQLSVMGAVGAQYNISNRVGLYVEPGVSYFFDDGSSIQTIRKENPCNFTLQAGIR
                     LTY"
     CDS             9528..9803
                     /locus_tag="ctg220_7"
                     /transl_table=11
                     /translation="MELVRMAGTVCSGKTSGATAKAGTDVCRISFPTGLCNSHRLTDET
                     ATSNTAAAATAQRRKGIILCGPVIGAPETDNSFSNRSHPATGSGSE"
     CDS             complement(9863..10411)
                     /locus_tag="ctg220_8"
                     /transl_table=11
                     /translation="MEEQELAERCRQGDNLARKELYERYAGRMLSVCLRYAGDRETAQD
                     LMHDGFLKLFDSFDKFTWRGEGSLRAWMERVMVNTVLQYLRKNDVMNQSSALENAPEAY
                     EEPEGSSIDVIPQKVLMQFISELPAGYRTVFNLYIFEEKSHKEIARLLGINEKSSASQL
                     TRAKATLAAKVREWMKRND"
     CDS             10594..11298
                     /locus_tag="ctg220_9"
                     /transl_table=11
                     /translation="MKKLRMTLAASILLFLTAIVLQSCLDDWDDKYDTLFAVGTVKVIE
                     GKDYYFSLDEGSKLYPSDTTYVHDYAVIDGQRAFIYFRELEEKLPGYEYNAQIKHIENI
                     LTKDIYSMPAEKADSIGDDNINATDLWITGEYLNIKYQFYHSNNEDKKHMLNLVINEAS
                     TGENDKPDYVNLEFRHNAYNDSQLTLGTGLASFKLDNIAEQLKEKKGLNIRVKSLYDGE
                     RFMTIDIKKENN"
ORIGIN
        1 ggagagacag ggattcgaac cccgggtgcc tcgcagcaca acggttttca agaccgccgc
       61 aatcgaccac tctgccacct ctccaaaact tctttttcag aagtactttt cttttaaagc
      121 ggtgcaaaga tacaaatcat tttttattct acaaactttt ctgcacaaaa acagagcaat
      181 tataccaaaa ttcttgttta tacccactac ggaacgaaca taacggcatt taggctattt
      241 gttgaaattt atcaagggca agacagagtt ttataactta ctggctatca gtatatttac
      301 aaagagccac attcagtata cgattgaacc ctattcagta tacgactgaa tggcattcac
      361 tatacgactg aattaggttc agaatacgac tgttccttaa acctacatca tttgtaaata
      421 atgcagatta ttattcggtt cttgtttcaa ttcataaacc acatataaag aaagtattaa
      481 catctctact cccccggaca ttcactacct aataatagtt attttatgct gttcaacata
      541 aaaagagaag tatctcttat aaaattacgg aatttattca gtatttttgc gcgctctaaa
      601 ggataacatt atctaaccta ctaacaaaaa caaatattat ggaattgaac aaaaccttta
      661 ccaatgggct ttggaataaa gaaatcaatg tcagtgattt cgtcagtaaa aacatcgcac
      721 cctataccgg ggatgcatct ttcttgcagg gacctaccga acgtaccaaa cgtatctggg
      781 acatctgtct gaaggctctc gaagaagaaa ggaacaacaa tggcgtccgt tcactggaca
      841 ataccaccgt atctaccatc acttctcata aagccgggta tattgataag gacaatgaac
      901 ttattgtcgg tttgcagact gatgaactgt tgaaacgatc catcaaacct ttcggaggca
      961 tcaacgtggt agcaaaagca tgccgtgaaa acggagtgga agtggacgat aaagtaaaag
     1021 acatcttcac ccattaccgc aaaacacata acgacggcgt attcgatgta tataccgaag
     1081 aaatccgttc cttccgctca ctgggattcc ttaccggatt gcccgacaac tatgcccgcg
     1141 gacgtatcat cggcgactac cgccgattgg ctctctacgg catcgaccgt ctgattgaag
     1201 ccaagcagga ggacttgcgc aacctcaccg gcccgatgac cgaagcacgc atccgtctac
     1261 gcgaagaagt ggcagaacaa atcaaagctt tgaaggacat caaggttatg ggcgaatatt
     1321 acggactcga cctcagccat ccggctacat cagctcaaga ggccgtgcaa tgggtataca
     1381 tggcatatct tgctgccatc aaagagcagg acggagcagc catgtcactg ggtaacgtat
     1441 cttcgttcct cgacattttc atcgaatacg atttggctca cggcaagatt gacgagacgt
     1501 ttgcacagga actgatagac cagttcgtca tcaaactacg tatggtacgc catctgcgca
     1561 tgcagtcgta caatgatatc tttgccggcg acccgacttg ggtgaccgaa gccatcggcg
     1621 gacgcttcaa cgacggacgc gtgaaggtca ccaagacttc tttccgcttt ttgcagacgc
     1681 tatacaacct cggtccttct ccggaaccga acttgaccgt attgtggagt cccgaactgc
     1741 cggaaggctt caaggatttc tgcgccaaag tttctgtaga taccagctcc atccagtacg
     1801 aaaacgacaa cctgatgcgc gaagtgcgca actgcgacga ttacggcatt gcctgctgtg
     1861 tatcctacca agccatcggc aagcaaatcc agttcttcgg cgcacgtgcc aaccttgcca
     1921 aggccctgct gcttgccatc aacggtggcc gttgcgaaaa caccggaact gtcatggtga
     1981 aaggtattcc cgtattgacc ggcgagacac tgaagtttga ggaagttatg gccaactaca
     2041 agaaggtact gactgaaata gcccgtgtct acaacgaggc catgaatatc atccactaca
     2101 tgcatgataa gtattattat gagaaagccc agatggcatt catcgatacc gacccacgca
     2161 tcaatctggc atacggtgtt gccggccttt ccatcgccat agactcactg tccgccatca
     2221 aatatgccaa agtcactgca cgccgcaacg aaatcggcct gaccgaaggt ttcgacaccg
     2281 aaggctcatt cccctgcttc ggcaataatg acgaccgtgt ggaccacctg ggagtagacc
     2341 tcgtttacta tttcagcgaa gaactgaaaa agctgcctgt ctacaagaat gcccgtccca
     2401 ccctttcctt gctgactatc acctccaacg tgatgtacgg caagaagacc ggtgccactc
     2461 cggacggacg cgccaaaggt gttgcctttg ctccgggtgc caacccaatg cacggacgtg
     2521 acaagaacgg tgccatcgct tccttgagct ccgtagccaa attgcgctac cgcgactcgc
     2581 aggacggcat cagcaatacg ttctccattg ttcccaaatc actgggcccg acaccggaag
     2641 aacgtgtaga gaacctggta accatgatgg acggctactt caccaaaggt gcccaccatt
     2701 tgaacgtaaa cgtactgaac cgcgaaatgc tggaagatgc catggaacat cctgaaaagt
     2761 atccgcaact caccatccgc gtttccggct atgccgtgaa cttcgtgaag ttgagccgcg
     2821 agcatcagtt ggaagtcatc agccgttcat tccacgaaag aatgtaatat gataaatgta
     2881 cactcctacg aaagtatggg aacattcgac gggccgggtc tccggctcgt cgttttcctg
     2941 caaggatgtc cgttccgttg tctgtattgt gccaatccgg atacgattga tgtaaaagga
     3001 ggcactccca ccactccgga agagattctg caaatggcta tcagccaaaa ggcattcttc
     3061 gggaagaaag gaggtattac tttctccggc ggtgagccta ccctgcaagc agaagcgctg
     3121 attcctcttt tcaaggagct gaaggcgaac gacatccata tctgtctgga cagtaacgga
     3181 ggcatctgga atgaaaaggt ggaagagctc tttagtctga ctgacctcgt gctgctggac
     3241 atcaagcaat tcaatcccga acgccaccgt acgctgacgg gacgaagcaa cgaacagaca
     3301 ctccgcaccg ctgcctggct cgaagaacat gaacacccct tctggctgcg ctatgtactg
     3361 gtccccggtt acagcgattc ggaagaagac acccgcctgc tgggtgaaag tcttggcaaa
     3421 taccagcaga tacaacgggt ggaaatactt ccttatcacc gtctgggtgt tcacaaatac
     3481 gaagccatgg gatgggatta caaattgaaa gaagtgaagg aaaatactcc ggaacaactg
     3541 gaacgggcag aaaaactgtt caaagagtat ttcacgaatg tgataaccaa ctaaaacaga
     3601 aaagcaaggc tgtccggata tgattccaga cagccttgct tttcatttat agggtaagaa
     3661 tcctattctt tcaagttata ggtaatctgc tgtacatcat cactactgcc acccaccata
     3721 aagacgaaat caccaggttc taccatataa ttcatctcat tgtcatagaa tcccagtgca
     3781 tcgtcagtta tctgaaaagc tacagttttg ctttcaccca cattcagatg aattttcctg
     3841 aagcccttca attcctttat cggacgcgta acagaggcta ccttatcctg cacatacaat
     3901 tgaactactt cctctcctgc acacttaccg gtattagtca cttttaccga cacctccgta
     3961 tggacgcctg cagccttgcc cggcagcagt ttcaaatcag aatatccaaa atccgtgtac
     4021 gaaagcccat atccgaaagg ataggcaggc tcagtggaag catcgatata agatgcctta
     4081 taggtctgtt tcaatgcggt agggcggccg gtgctcttat tctgataata aatgggaatc
     4141 tgtcctacgt gtgcaggaaa tgtcatgggc aatttagccg aaggattata ctctccccac
     4201 aacacattgc atatggcatt gccggcctca cttcccagcc accaagtaca cagtaccgca
     4261 tcagcatgtt cccttatctc attgaagatt accggacgcc cacacatgac aagagcaatg
     4321 acaggttttc cagtctttgc cagttccgac accagcttct gctgcccctc gggtatggct
     4381 atattcactt tggaagcctt ctcgccactc tgaccgaatc tctcgcctac cgccacaaca
     4441 atgacatccg aagcctcagc agcctgtaat gcttcctgca atccggtcaa ttgattgctc
     4501 ttcatatcat agccttcagc atagttcacc tccagtcctt tccggaccaa tgcatcatat
     4561 aaggtcacca ctttgttccg gtccgtagtg gcagcccaag cacctgccat atcgtactgg
     4621 gattttgaga gtcctcctat caaggctatc ttcctcgtct gtgccgtcaa cggaagcaca
     4681 gattccctat tctccagcaa tacaacggaa cgctcggcca tacggagcga agcattacgg
     4741 acttcgggcg cattgagtat tctggctgct ctttccggat tacagtagcg aaaagggtcc
     4801 tcaaacaatc ccaactcata tttcttctcc aaaatacgcc gtactgcatc atcaagcaca
     4861 ctctccttta ctttcccttc ttgaacaagc tccttcagat aagtcaagta gcaggtactt
     4921 accatctcca tgtccagacc agcattcagc gctttggctg cggcatcttt cttgtcagca
     4981 gcataacggt ggttcaccaa ttcctctacc gaattataat cggacacaac aaatccctta
     5041 aatccccact gctctctcaa tagccggttg agcaagaaat cattggcagt acaaggaata
     5101 ttattaaaat cattgaaagc actcatcacg gtagctgctc ctgcctttat ggccgcctta
     5161 tagggaggca tataaaaatt ggcaaagtgg cccattgaca tatccacact attatactcc
     5221 tttcctgcta tcggtgcacc atatccggca aaatgtttca tacatgccat gacagtcgtc
     5281 gtgtccgcca aatcgtctcc ttgcaagcct ctgacacgcg cctccgctac ccgagaacca
     5341 taataagggt cctcaccggc cccttccatg acgcgtcccc aacgtgcgtc ccacgaaata
     5401 tccaccatcg gggcaaaaac ccagttcaaa ccatcggcgg cactttccaa agcattgtag
     5461 cgtgcagctt cctcaatcat ggccaaatcg aaacttgcag cctcggcaag cggaagcgga
     5521 aatccggtac gatagccgtg gataacatcc agtccgaaaa ttaaaggaat gcgcaaacgc
     5581 gattgcaaag caagctcttg ataacggcgt atatccttta ctcctatcac attcagcata
     5641 gagcctattc tgccttgccg gacatactct tctttaggaa tatttccacc gtcgggtccg
     5701 gtaaaattcc ctcggtaggt gcattgtgca agctggccta tcttttcatc cagcgtcatc
     5761 tgcttcatca agcttgagat gaatttctcc ttctccgtag tttgtgccga ggtaaaggtg
     5821 ttaccaagtc cccacagaca aaccatcagt attattatct ttttcatact gccattcttg
     5881 ttttgatatt tattttatca taaaacaaca gttgccttca atggtaaatc agctgaagaa
     5941 ggacctgcca gaatctcaaa agtccccttt tccactacaa accgatgtga ttccacatca
     6001 tagtaggcaa aggcttcctc atccagcaat atccggatgc gcttggtttc ccccttcttc
     6061 aagtaaacct tatcgtagcc tttcaactcc ttcaatggac gcggaacaga acattccaca
     6121 tcccgcacat atacctgagc cgcttctgca gcatccatct ttccagtatt cttgatgtca
     6181 aagcttaccg taacccggtt tccacccgtc ttctcaacac tcagattact gtattcaaaa
     6241 ctactgtatg acagtccata cccgaaagga tagagcggct gttttccatt ccggtcatat
     6301 cccctataac ctacgaaaac accttcggca tactgcaccc gtttatgagg tacattgcga
     6361 ttgtcataat aattaccata taccggatta tcttcccatt tttcctcgat gctgactggc
     6421 agtttgccac ttggcgaaag cttgcccgta atgatttcgg caagggcctt tccaccctcc
     6481 tgccccggat accatgccat caaaatagct tgtacattct gcccccaatt gcggaaatct
     6541 attccacctc cggcattcac caccacagtc acattatcat gaagtgaagc cactttatta
     6601 atgagatatt cctgcccgta tgacaatgca aacggacggt cgaacccttc accttctgta
     6661 ctgctgttga acccggcaca tacaataaca ttcctggcat gcttcagtga agaggccaaa
     6721 cgctcctcat ccatcattcc tgcctggaaa ctgacagtcg cctcacccac attatcaaaa
     6781 tattcaatac gcagccggta tatctcccct gtactgacct gcataaatgc actgcgggta
     6841 ctgaatgaat ggttccccca atctccggta atcagcttat cgtttacaaa cagacggtat
     6901 ccgtcatcgc cagccagctg gaacttgaca gttccatcct tgtcagcctt gtaaactccc
     6961 gtccaacggg cagaaaactg atctaccggc atgccgtcga acggtgcacc gtatttccag
     7021 gcatagtcta tggcaggctc tatgacagcc tgaaaaagtt ctccggtaag attacgagta
     7081 ttataatatt cgctcttaaa accgttttgc gtaaaactgt catccgtata aatctgttgg
     7141 gacatatcct tataaagaag gctgtcagac agcagttcta tctgtctgcc gcccttcaac
     7201 tgaaccatac cgtcatagag cgacactacc gaataaggag tgacaaatcc gcttcctcct
     7261 cctgtgggaa taatatcggc attaggcccg attaccaatg ttctaccgtt ccggtaaggc
     7321 aacgtaccgt tgtcattttt caataacact actccttccc tcgccaagtc aagtgcaatt
     7381 tccttagact gtgcattgtc tttatcgata gatttatctt ctctcggagt atcaagtgct
     7441 ccaaaagcaa tcaatgtctg gagtatatgc cggactttgg cgtcaatggt ctcttccctc
     7501 acgataccat tctctattgc cggaataaga atctccctgg tcatgaattt accgacgggc
     7561 atttccaaat ccaaccctcc attagcggct cccacaccgg aatatacaga tgtccagtcg
     7621 gacatcaaga tacctttaaa tccccactgc ttgcgtaata catcaatgtt cagccagctg
     7681 ttttcggtgg catgcacccc gttcagcgga ttatagctat ccatgaccgc tcctactcct
     7741 gcttcctgca cagcttttcg gaacgcggga aaataaattt cctgcaacgt gcgttcatcc
     7801 acatccgagc tggcatgatg cctgctccac tcctggttat tggctgcaaa atgcttcacc
     7861 gtagccatga ctccctcttc ctgcactccc aagatatatt ctttggctgt ttcgcccgtc
     7921 agataagggt cttcaccaaa atactcatag tttcgcccgc atagaggaga gcggtagata
     7981 ttgactccag gccccaacag aatacttacc ccacgggcct ttgcatcccg ggccaaacca
     8041 tgtcccagct ctctagccaa cttacggttc catgtcgaag ccgacaagat gccacaagga
     8101 tacaaggtac tttgagtatt gttacgtatg ccttgcggac catcggccat cctgatttcg
     8161 ggtatgccaa gccggggtac agcccggata taaaaagatt tgggaccgga aatgtaatcg
     8221 attttttctt ccagcgtcat ttgagaaacc aactccctgg cacgctgctc cacctgggga
     8281 gtaatacaca cttgtgcttt tgccgtgatt gcacaacaaa gcaatagccc gcttaaggct
     8341 actttctttt taatcttcat tttgtctatt ttactacgtg tttgttatat tgccgggcat
     8401 gtcccgacct actttctttc ttctcaatca ataaaaaacc gtgtcccttc atccaccaac
     8461 gaagaaacac ggccgaaagt tattaagaaa attctgaatc tacaagaaag tggacaaaaa
     8521 catgtctgtc ctgctatcaa taagtaagac gtataccggc ctgcaacgta aagttacacg
     8581 ggttctcctt gcgtatagtc tgtatcgacg aaccgtcatc aaagaaatag gatactcccg
     8641 gttccacata caggcccacc ctattgctta tgttatactg ggcaccgaca gcacccatga
     8701 cagaaagctg taccggtttc acagtctcac tctcagtacc aatcttgcca tacacacatt
     8761 tttcaatggc accccccgcc gaaacataca tcgtaaagtt ctttgtatcc acaaagttcc
     8821 agttggcccg taccggaatg ccaatataat gcagcttctg gcttatcttt tccgagctgc
     8881 cctcatacct tacgtcagaa gcaagatagg tatacgtcag cccgctttcc acagagaaac
     8941 ccttcgccaa gtttttccgc accgaaacac cgaaactgag cggttgttta tggtctatat
     9001 ccgcaatttt cttttcgcgt ctttgcagat agggcatacc atccttaaaa accagttcct
     9061 gcccgtcggg aatagtaaca atgccattgg ccgtagagga taaatctacg ttaccgccat
     9121 aaataggact tccaggcatg tagtccgaca tcacattcgc ttccccttca ttcgccaatg
     9181 aaaaacctcc cgtatttcct acggacaagc caaccgccca tcctttagca tccctaccag
     9241 aactgttttt ttccggaaga tgcagtttgt cccggcctga cggacgatag cggtcttccc
     9301 ttgtctccgg ttcctcggcc tgcattgtag tttcatggtc cgtatcttcc actaccggtt
     9361 cttccgcctg ctgtccaata ccgacaacct catctgcagt ttcaaccggc agcatttcct
     9421 cctgctgttc ttcgccaacc gatattctga tatgttgtgc aaccaaaggg tgacttgcct
     9481 ccttattggg cgccgatgca tttccatgtg cccgataagc aggctctatg gaattagtcc
     9541 gtatggcagg tactgtctgt tccggcaaga cgtccggagc cacagccaaa gcgggcactg
     9601 acgtatgccg catttcattc cctaccggac tctgcaacag ccacagactg acggacgaaa
     9661 ccgccaccag caacacagct gccgcggcca ccgcccagcg acggaaaggt atcatcctat
     9721 gcggtccggt tatcggagct ccggaaacgg acaattcctt ctccaaccgc tcccatccgg
     9781 caaccggcag cggttcggaa tagtcttcca gcttgtcctt tatctttttc aaccacaatt
     9841 catcttccat acgttccttc atttaatcat ttcttttcat ccactcacgt acttttgccg
     9901 ctaaagtcgc tttagcacgc gtcaactgcg aggcagagga tttttcatta attcccaata
     9961 gtcgagcaat ctccttatgg gatttctctt caaaaatata taagttgaat acggtacgat
    10021 agccggcagg caattcactg ataaactgca tcagtacttt ttgaggaatg acatctattg
    10081 acgaaccttc cggttcctca taagcttcgg gtgcattctc caaggccgat gactgattca
    10141 tcacatcatt tttccgcaaa tactgcaata ccgtattcac cattacgcgt tccatccatg
    10201 cccgcagaga accctctccc cgccaagtga acttatcgaa agaatcaaaa agcttcagaa
    10261 aaccgtcatg catcaggtct tgggcagtct cccggtcacc tgcataacgg aggcatacgc
    10321 tgagcatgcg tcccgcatag cgctcataca gttctttgcg ggcaagattg tctccttgcc
    10381 tacagcgttc tgccaattcc tgttcttcca ttctctcttt taacacgtgt ttaccctata
    10441 aatgcaatcg gcgcaaaaat actgcatcag gcagagaaga aaatcatact ttcatttctt
    10501 taacagtata ctacgcagta tttagctttt caccgcattt tctgaataca aaaataagtt
    10561 ttaaacagaa aaaagagcta aaacctacca cttatgaaga aactgagaat gacattggca
    10621 gcatccatac ttttattcct gactgccatt gtattgcaat catgcctgga cgattgggat
    10681 gacaaatatg acactttgtt cgccgtaggt acggtaaagg tcatcgaagg aaaagactac
    10741 tatttctcac tggacgaagg cagtaaacta tatcccagtg acacaaccta tgttcacgac
    10801 tatgccgtaa tagacggcca gagggctttc atctacttcc gcgaactgga agagaaactt
    10861 ccaggctacg aatacaatgc ccaaataaag cacatcgaaa acattctgac caaagacatc
    10921 tactccatgc ctgccgaaaa ggcggacagt atcggagacg acaacatcaa cgccacggat
    10981 ttatggatta cgggcgagta tctgaacatc aaatatcaat tctaccacag caacaacgaa
    11041 gacaagaagc acatgctgaa cctggtcatc aatgaagcat ccaccggcga aaacgacaaa
    11101 ccggattacg tcaatctcga attccgccac aatgcctaca atgacagcca gctcacgctg
    11161 ggcaccggac tggcctcctt caagctggac aatatagcgg aacagctgaa agagaaaaaa
    11221 ggactgaaca tccgtgtcaa aagtctatat gacggtgaac ggttcatgac catagacatt
    11281 aaaaaagaaa acaactaaat ctcctgaaaa cacatctttc aacatctcaa tgagaagcgg
    11341 agtgacattg caatatgttg ctccgcttta tttttccata tcccgcttaa attcatcttt
    11401 ttctttgtct atccaccggg aaacccctac atttgtaaga attttcacaa tagcaaacat
    11461 taaaacggtc caaaggatat gaaatacata ctgggagcag taattgcaat actctgctcg
    11521 ttcacctgca cagacaccct atatggaaaa tctcccgcaa cagacgtcga cgatattctg
    11581 ataatcaaca cttatacaga agccaatccc tggagtaatg atttcatcac ctccattgtg
    11641 aacatggcat cacagaacag ccacatcgga gtatacaccg cacacatgaa aatgctgaca
    11701 cttgacgagg aaaataaact ggagacattc aaagagagct tgttcaagag ttacaagaac
    11761 cctaaactta tcgtgcttat cggatgcgga agtttcatca tgtgcgatga actgaaccgg
    11821 cagtggcccg atatccccat gatattatgt ggtgagaggg attataccgg tcctaaggaa
    11881 acaatgatac gcgagcacgc cctgccccgc acagagcgta ttcccatcag tgacctacag
    11941 aagaagtaca atctgacctt aatgcaatcc agtgtatacc tgaacgagaa cctgcaactc
    12001 atgaagcaac tcatccccaa aatggataag gtcatgtata taggggatga aacatacatc
    12061 tgccagcaga acgactatga cttgtccgag attatccgtg aaaagtatcc ggagttggat
    12121 taccagttcc ttagtgcgaa agacatccga acggacagcc ttttcaatat actgaaccac
    12181 gtgaatcccc atactaccgg agtcatcttt tcatcctggc tgtacaagag ctctccccat
    12241 gacaatatca tgaggagtaa ttcccaccgg gtcatctcta ccgcccccat ccctttgttt
    12301 tcgctaaggg ccatcggtat tgaagaagaa ggggggattg taggcggcta catttacaac
    12361 aaagagaaat ataatgcccg gctactggaa accatccaca agatattgga tggtaccccg
    12421 gcacgcaaca tcccgttata ctatcccgac gacggagccc ccgtattcaa ctataaatcc
    12481 cttctgcagc gtgacctgaa tccgaagcta tgccccaagg gtaccatatt ctacaacatg
    12541 cctcccacct tctgggagaa gtacgaatat gtcattatca gtatcactgc cgcaatcata
    12601 actctgctgt tctttttcca atatctccgc ctacagtcac tgagtagaat caaaagatta
    12661 caacagcaac aactggacag caatctcaaa taccgaaatc tgataaacaa catgcccatc
    12721 ctatacatgt atgagaaact tataaaagat gaaaaagggc gcattactga caccttatat
    12781 atagatgtca acaatttctt cgaagacaga tttatcatgc gcaaagaggc tgtcggcaag
    12841 cggggaagcg aattatttcc cgaatccatg aacgagttcc tccatttcat gaatattgca
    12901 ttgaaggaga aacgttccgt aactttcccc tattattaca agaagataga cactttctac
    12961 gacattgtag tcaaggcaag cgacaatggc gaatacatgc acgtcttctg cgttgacagc
    13021 accgagttgc accacaccca aatacagttg aggtcgacaa accggaaact ttccatggca
    13081 ctcgacgttg ccaacatcgt accatggaaa tggaacctcc ggacacacac catactctgc
    13141 gatgtcaaca agccgataga gctcagcaat aatgccggta tcatggacga tgaacagctg
    13201 tccgtacccg acagccagta tttctccaaa atacacaagg aagacctgga aaaagtgaaa
    13261 caagcctata cagacctgat tgagggacgt atccagaaag tcaaggagga ataccgcgtc
    13321 atcaatcatg ccgacagaca caaacacttc gactgggtgg aggcccaggc cgccgtagaa
    13381 acctacgacg agaacaataa gccgctgacc ctggtgggct cttcgctggt tatcaccgaa
    13441 cggaaaaaga tggagacgga actggtttcc gccaagaacc gtgcggaaga gtcgaataaa
    13501 ctgaaatccg cattcctcgc caacatgagc catgaaatcc gtacgccgct caatgccatt
    13561 gtgggattct ccggaatatt ggcttccacc gaag
//
