LOCUS       c00183_gnlPro..         3383 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AKFPGBAL_183.
ACCESSION   c00183_gnlPro..
VERSION     c00183_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 12:51:15
            Original ID  :: gnl|Prokka|AKFPGBAL_183
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3383
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3383
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:3383]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..3383
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..3383
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..3383
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(3..923)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg183_1"
                     /sec_met_domain="IlvN (E-value: 2.9e-46, bitscore: 145.5,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.3e-35, bitscore: 110.5,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGVTENVVTREEFPLEKAREVLKNETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRPGKTYEKAVADGWVPGETLFGIEEACEKGTIIMCLLSDAAVMS
                     VWPTIKPYLTAGKALYFSHGFAITWSDRTGVVPQKDIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAIYQDATGRAMERTIALGIGVGSGYLFETTFVREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMG
                     PFHDAIKPVVQKLYNSVKTGNEAQIS"
     CDS             complement(1005..1589)
                     /locus_tag="ctg183_2"
                     /transl_table=11
                     /translation="MKKIVFLLLLCVACCMNAQEFHLIPKVGLNLANTTGEVDSKVRPG
                     LNIGLGGDVMLTERFGIETGVYYSMQGSKYKGGGVSYTDKLDYINVPVYAKEFIYKGLY
                     VFGGPQFSFNVNSENKSSSDYGTTVIGMNVIRKFDCGVGLGAGYQFERGLLISLNYNIG
                     LINVNKSWASDSNPKANNSVVQLNVGWRFAL"
     CDS             complement(1607..2350)
                     /locus_tag="ctg183_3"
                     /transl_table=11
                     /translation="MSDDKKIGSYKFIAEPFHVDFNGRLTMGVLGNHLLNCAGFHASER
                     GFGIATLNEDNYTWVLSRLAIDLEEIPYQYEEFTVQTWVENVYRLFTDRNFAIIDKDGK
                     KIGYARSVWAMINLNTRKPADLLTLHGGSIVDYVCDEPCPIEKPSRIKVATDQPCAKLT
                     AKYSDIDINGHVNSIRYIEHILDLFPIDLYKSKRIQRFEMAYVAESYYGDELSFFEEEV
                     SENEYHVEIKKNGSEVVCRAKVKFV"
     CDS             complement(2351..2911)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg183_4"
                     /sec_met_domain="ALS_ss_C (E-value: 1.7e-19, bitscore:
                     58.4, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKTLYTLIVHSENFAGLLNQVTAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTDKDTIEKVVKQIEKKIDVLQAHYFTEDEIYFHEIALYKVSMPEFQSQPE
                     ASKVIRRYNARIVEVNPVFAIVEKNGISEEITSLYEELSALNCVLQFVRSGRVAITTSC
                     FERVNEFLADRETKYNLSKKEEK"
     CDS             complement(2925..3383)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg183_5"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8.4e-43, bitscore:
                     134.3, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="ITSGGLGTMGFGLPAAIGATFGRPDRTVCVFMGDGGLQMNIQELG
                     TIMEQKAPVKIIVLNNNFLGNVRQWQAMFFNRKYSFTPMLNPDYIKIASAYDIPAKRVF
                     TREELADAIDEMIATDGPFLLEACVIEEGNVLPMTPPGGSVNQMLLEC"
ORIGIN
        1 atagagatct gtgcctcgtt accggtcttt acactattat ataatttctg aacaacgggt
       61 ttaatagcat cgtggaacgg gcccatccag tcaagagcac cacgctgagc cgtagtcgag
      121 cagttggcat acatccaatc cataccattc ttagcaaaca gcggcatcaa tgactgagtt
      181 aactcctcaa ccgtttcgtt aaatgcctca gatggagtat gaccgttctc acgcaaaacc
      241 tcatactgag ccaacagcaa accttgtata gctcccatca gcgaaccacg ttcacctgtc
      301 aggtcggaag tagcttcacg gacaaaagtc gtttcaaaca gatatccgga acctacaccg
      361 atacccaatg cgatggttct ctccatagct ctgccggtag catcctgata gatggcatac
      421 gaagagttca gtccgcgacc ttcaaggaac atcgtacgga gtgaagtacc cgaacccttc
      481 ggagcgacca taatgacatc gatatctttc tgtggaacaa caccggtgcg atcgctccat
      541 gtaattgcga aaccgtgaga gaaatagagt gctttcccgg cagtcaggta aggtttgata
      601 gtaggccata cagacattac ggctgcatct gacaacagac acataataat agtacctttc
      661 tcgcatgcct cttcgatgcc gaacagtgtt tcacccggaa cccagccgtc tgccactgct
      721 ttttcatatg tttttcccgg acgctgacca acgattacat tgaagccatt atcgcgcagg
      781 ttcagtgatt gacccggtcc ctgcacaccg taaccgataa cagcgattgt ttcattcttc
      841 aatacctcac gagctttttc caaaggaaat tcttcacggg ttactacatt ttccgtaaca
      901 ccgccaaaat tcaattgtgc catttttctt tttgttttaa aagtcttgtt ccgttcggac
      961 gaaaacaaaa ccgattatta ataattaaac ttatattctt tatcttacag tgcaaaacgc
     1021 caaccgacat ttagctggac cacactattg tttgctttag gattagagtc gcttgcccaa
     1081 gatttgttta cgttaatcag tccgatgtta tagtttagag agatcagcag accacgttca
     1141 aactgataac cggctccaag ccccactcca caatcaaact tgcgaatcac attcatgcct
     1201 atgactgtgg taccatagtc ggaggatgat ttgttctctg agttcacatt gaaactgaac
     1261 tgcggccctc caaacacata cagcccctta tatataaatt ctttcgcata taccggaaca
     1321 ttgatataat ccagtttatc cgtataagag actccgcccc ctttatattt gcttccctgc
     1381 attgagtaat acactcctgt ttctattcca aagcgttcgg tcagcatgac atcacctccc
     1441 agaccgatat tgagtccggg acgcacttta gaatccacct ctccggtagt atttgccaga
     1501 ttcaaaccga ccttcggaat cagatgaaac tcctgtgcat tcatacagca agcaacacag
     1561 agcagcaaaa gaaaaacaat cttcttcatt ttaatcacat tttaaactac acaaacttca
     1621 cttttgcccg gcatacaact tcactgccgt ttttcttaat ctcgacgtga tattcattct
     1681 cacttacttc ctcttcaaaa aaagaaagct cgtcgccata ataactttct gccacatagg
     1741 ccatttcaaa tcgctgaatc cgtttcgatt tatacaaatc gatcggaaac aaatcgagga
     1801 tatgttctat ataacgaatg ctgttcacat gaccattgat gtcgatatcg ctgtatttag
     1861 ctgtcaactt agcacaaggt tggtcagtag ccactttgat acgcgaaggc ttttcgatcg
     1921 gacaaggttc gtcacataca tagtccacaa tactaccgcc atgcaacgtc agcaaatcag
     1981 ccggcttgcg ggtatttaaa ttaatcatgg cccataccga acgggcatat ccgatcttct
     2041 tgccgtcctt gtctataatg gcaaaattac gatcagtaaa aagacgatat acattctcca
     2101 cccatgtctg tacagtaaac tcctcatatt gataaggtat ctcttccaga tcgatggcca
     2161 gacgagacaa tacccatgta taattgtcct cattcaatgt agcgattcca aagccgcgtt
     2221 cactggcatg aaagccggca cagttcaaca gatggttgcc aagcaccccc attgtcaaac
     2281 gtccgttgaa atctacatga aaaggctccg caataaactt ataactccct atcttcttat
     2341 cgtcactcat tcacttttcc tctttcttgc ttaagttata tttggtctca cgatctgcca
     2401 gaaactcgtt cacacgttca aagcaactgg tagtgattgc cacacgtccc gaacgcacaa
     2461 attgcaacac acaattcaat gcactcaact cttcgtagag agaagtaatt tcttcactga
     2521 ttccattttt ctcgacgatg gcaaataccg gattcacttc cacaatccgt gcattatagc
     2581 gacgaatcac cttcgaagct tccggctgtg actgaaattc gggcatagac accttataaa
     2641 gagctatttc atgaaaatag atttcatctt cagtgaaata atgtgcctga agcacatcga
     2701 tcttcttctc aatctgtttg acaaccttct ctatcgtatc tttatcggtc caagccgtaa
     2761 tagtatattt atgcaccccc ttgatagatg aagccgaaac attcaggctt tctatattaa
     2821 tctgccgacg ggtaaatact gccgtaacct gattcaacaa tccggcaaag ttctctgaat
     2881 gaacaattaa tgtatataat gtcttatcca taattcctaa cttattagca ttccaacaac
     2941 atctggttaa ctgaacctcc cggaggggtc atcggcaaca catttccctc ttcaatcaca
     3001 caagcttcca acaggaacgg accgtctgtc gcaatcatct cgtcaatcgc atcagccagt
     3061 tcttcacggg taaagactct tttggccggt atatcataag cagaagcaat cttaatataa
     3121 tcgggattca gcatgggtgt gaacgagtat ttacggttga agaacattgc ctgccattgg
     3181 cgtacattgc ccaggaaatt attgtttaat acgataattt taaccggtgc cttctgttcc
     3241 ataatggttc ccaactcctg aatgttcatt tgcagaccac cgtcacccat aaatacacaa
     3301 accgtacggt ccggtcggcc aaaggttgca ccgatagcag ccggcaaccc gaatcccatg
     3361 gtaccaagtc ctccggaagt aat
//
