LOCUS       c00017_gnlPro..         6140 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DFLFNFPM_17.
ACCESSION   c00017_gnlPro..
VERSION     c00017_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 12:51:47
            Original ID  :: gnl|Prokka|DFLFNFPM_17
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6140
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6140
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[337:4894]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      338..4894
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..6140
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..6140
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(2..238)
                     /locus_tag="ctg17_1"
                     /transl_table=11
                     /translation="MGEVRACAPTHEIMRKEKVFLMNNLYTFAYMRKDLNGARHFSIGI
                     KFTILLFTIAILVLVLFSYRSDKHGNLFWQVEKL"
     CDS             338..742
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_2"
                     /sec_met_domain="Glyoxalase_4 (E-value: 7.4e-25, bitscore:
                     76.4, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGETKIELLEPTCPESTIAKFIENKGAGVHHVAFAVEDGVANALAEAESKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             771..2324
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_3"
                     /sec_met_domain="CT_Btheta (E-value: 1.1e-290, bitscore:
                     953.0, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIERRAVARIGGGEKAIAKQHEKGKYTARERLAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYVFAQDFTVSAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAQTEEEGFELIRKLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDSPT
                     KPYDMYEVIGAIVDNGEFLEIQKDYAKNIIIGFARFNGQSVGIVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKDQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLSNPAKKHGNIPL
                     "
     CDS             2356..3276
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_4"
                     /sec_met_domain="OAD_gamma (E-value: 3.9e-16, bitscore:
                     48.5, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLLLLIGLTSCGEQKSNNKLVLNEILINNQSNFQD
                     DYGLHSAWIEIFNKSFGSADLAACLLKVSSQPGDTVTYFIPKGDILTLVKPRQHALFWA
                     DGEPNRGTFHTSFKLNPETANWVGLFDSGKKLLDQIVVPAGALGPNQSYARVSDGAAEW
                     EVKSGSGDKYVTPSTNNKTLDSNSKMEKFEEHDADGVGMSISAMSVVFCGLILLFIAFK
                     IVGKVAVNLSKRNAMKSKGIDKHEAKELSQAPGEVYAAISMALHEMQDEVHDVEETVLT
                     ITRVKRSYSPWSSKIYTLRETPPRK"
     CDS             3301..3732
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 67.7; E-value:
                     2e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_5"
                     /sec_met_domain="Biotin_lipoyl (E-value: 2.3e-22, bitscore:
                     67.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNSYKVTIGDIEDNIAHVEVNGTHYKVEMEKQPKPV
                     AKPVTVRPMPNAPAAPTQVVKPTAPSTGKSGVKSPLPGVILDIKVNVGDTVKKGQTIII
                     LEAMKMENNINADKDGKITAINVNKGDSVLEGNDLVIIE"
     CDS             3734..4894
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_6"
                     /sec_met_domain="OAD_beta (E-value: 1.3e-153, bitscore:
                     499.9, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFINFLGNNLADFWTYTGFANATVGHVVMILVGLGFIYLAVAK
                     EFEPMLLIPIGFGMLIGNIPFNMDAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYMIALEMGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRLLTTKNERVIRMKPPRAVSHTEKVIFP
                     IIGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDTITILLGLTVGAS
                     TQASEFLTLDSIKIFALGALSFVIATASGVIFVKIFNIFLKKGNKINPLIGNAGVSAVP
                     DSARISQVIGLEYDSTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             complement(5079..6083)
                     /locus_tag="ctg17_7"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTREMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCAHPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSADHHT
                     YTDPEEVIDFATRTGCDSLAISIGTSHGAYKFTPEQCHIDPKTGRMVPPPLAFEVLDAV
                     MEKLPGFPIVLHGSSSVPEEEVETINKYGGALKAAIGIPEEELRKAAKSAVCKINIDSD
                     SRLAMTAAVRKVFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSDNKLAQ"
ORIGIN
        1 tcaatttctc tacctgccag aacaggttgc catgcttgtc gcttctatat gaaaaaagca
       61 caagaaccaa gatcgcgatc gtaaacaata agatcgtaaa cttgatccct atggaaaaat
      121 gccgtgcccc attcaaatcc ttacgcatat aggcaaatgt atataaatta ttcataagga
      181 aaaccttttc cttccgcatt atttcatgtg tcggggcaca tgccctgacc tctcccatta
      241 atgcagaaat atttctttat taggtaagaa atgtctttct ttgtgctgtt ttatgccgta
      301 taagcacata attaaaacca aataaaaaag tatagttatg aagatttcac acattgaaca
      361 tctgggcatt gctgtaaaaa gcatcgaaga agcccttcct tactacgaaa atgtattagg
      421 tctgaagtgt tacaacattg aaacagtgga agatcagaaa gtaagaactg cttttttaaa
      481 agtaggcgaa accaaaattg aactgttgga gccgacttgc ccggagagta ctattgccaa
      541 attcattgaa aacaaaggtg caggtgttca tcatgtagcc tttgctgtag aagatggcgt
      601 agccaatgct ttggcagaag cagaaagcaa agaaatccgc cttatcgaca aagctccccg
      661 caaaggtgcc gaaggtttga atattgcttt ccttcacccg aaatcaactt tgggcgtgtt
      721 gacagaactc tgcgaacatt aatcataaac tctaaaacca acaagaactc atgagtaatc
      781 aacttgaaaa aattaaagag cttattgaac gccgtgccgt agcacgtatc ggaggcggcg
      841 aaaaagcaat tgcgaagcaa catgaaaaag ggaaatacac agcacgcgag cgtttggcta
      901 tgctgcttga cgagggtagc ttcgaagaaa tggacatgtt cgttgagcac agatgcacga
      961 acttcggaat ggagaaaaaa cattatccgg gagacggtgt agtaaccggc tgcggtacaa
     1021 tcgaaggacg tctggtatat gtgttcgcac aggacttcac tgtttctgcc ggttcactgt
     1081 cagaaacaat gtcattgaag atttgtaaaa ttatggatca ggccatgaag atgggtgctc
     1141 cttgtatcgg tatcaacgac tcgggtggtg cacgtatcca ggaaggtatc aacgctttgg
     1201 caggttatgc agaaatcttc caacgcaaca tccttgcttc aggtgttatt ccgcagattt
     1261 ccggtatctt cggtccttgt gccggtggtg ctgtttattc tccggctctg accgacttta
     1321 cactgatgat ggaaggcact tcttatatgt tcctcaccgg accgaaagtg gtgaagaccg
     1381 ttacaggtga agacgttagc caggaaaacc tcggtggcgc aagcgttcac tccactaaat
     1441 cgggtgtgac tcatttcacc gcccaaacag aagaagaagg tttcgaactg attcgcaaac
     1501 tgttgagcta tattcctcaa aacaaccttg aagaagctcc ttatgtagat tgcacagacc
     1561 caatcgaccg tctggaagat tctttgaacg atattatccc cgacagccct actaaaccgt
     1621 atgacatgta cgaagtgatc ggcgctattg tggacaacgg tgaattcctt gaaatccaga
     1681 aagattatgc aaagaatatc atcatcggtt tcgcccgttt caacggacaa tcggtaggta
     1741 tcgttgctaa tcagcctaag tatctggctg gtgtactcga tagcaacgca tctcgtaaag
     1801 gcgcacgttt cgttcgtttc tgcgatgcat tcaatattcc tatcgtatcg ttggtagacg
     1861 taccgggatt ccttccggga acaggtcagg aatacaatgg cgttatcctt catggtgcta
     1921 aactgttgta tgcttacggt gaagctactg tgcctaaggt tactattaca ttgcgtaaat
     1981 cttacggtgg ttctcacatc gtaatgagct gtaagcaact tcgcggtgac atgaactacg
     2041 catggcctac tgccgaaatc gcagtaatgg gtggtgcagg agcagtagaa gtattgtacg
     2101 cacgcgaagc caaagatcag gaaaaccctg ctcaattcct tgcagagaaa gaagcagaat
     2161 acacgaaatt gttcgccaat ccttacaatg cagctaaata tggctacatc gacgatgtga
     2221 ttgaaccgcg caacacacgt ttccgtgtga tccgtgcttt gcagcagttg cagactaaga
     2281 aattgagtaa tccggctaag aagcatggta atattccgtt gtaatcctac ttttcacatt
     2341 aaaacaagaa cgattatgaa caaaaccaaa atcggaatat tcctttcttt gctgttgctg
     2401 attggtctga cttcttgtgg agagcaaaag tcgaacaata agctggtgct aaacgaaatc
     2461 ctgataaaca atcagagtaa ttttcaggac gattacggat tgcacagcgc atggattgaa
     2521 atattcaata aatcattcgg tagcgccgac ctggcagctt gcttgctgaa agtaagcagc
     2581 caaccgggcg atacagttac ttattttatc ccgaaaggtg atatacttac cttagtgaaa
     2641 ccacgccaac atgcactatt ctgggcagat ggcgaaccta accgtggtac tttccatacc
     2701 agcttcaagc tgaatccgga aacagctaat tgggttggtc tgttcgactc cggcaaaaag
     2761 ttgctcgacc agattgtagt gcccgcaggc gctctcggtc ccaatcaatc atacgctcgt
     2821 gtaagcgacg gggcagctga atgggaagta aaaagtggaa gcggtgacaa atacgtgact
     2881 ccaagcacca acaacaagac tcttgacagc aattccaaga tggaaaagtt tgaagaacac
     2941 gatgctgatg gcgttggaat gtccatttct gccatgagcg tagtattctg cggattgatt
     3001 cttctcttta ttgcttttaa gattgtagga aaagtagctg ttaatttgag caagcgcaac
     3061 gctatgaaat ctaaaggcat tgacaagcat gaagctaagg aactgtcaca ggctccgggc
     3121 gaagtatacg ctgctatttc tatggcatta cacgaaatgc aggatgaggt gcacgacgta
     3181 gaagaaacgg tgctgaccat cacccgcgta aaacgcagct actcaccatg gagttcgaag
     3241 atttacactt tgcgtgaaac tcctcccaga aagtaagtca ccttttaaaa agttaaaacg
     3301 atgaaagaat ataaatataa aatcaacggt aactcatata aagtaaccat cggagatatt
     3361 gaagataata tcgctcatgt agaagtgaac ggtacacact ataaagtaga aatggagaaa
     3421 cagccgaagc ctgttgcgaa acccgtgaca gtacgcccga tgcctaatgc tcctgctgct
     3481 cctactcaag tagtgaaacc gaccgctccg tctaccggaa aatcaggagt aaaatctccg
     3541 ctgccgggtg tgatcctcga catcaaagtg aatgtaggcg atactgtaaa gaaaggacag
     3601 accattatca tattggaagc catgaagatg gaaaacaata tcaatgcgga taaggacggt
     3661 aagattactg ccatcaacgt caacaaggga gactctgttc ttgaaggtaa tgacctcgta
     3721 attattgaat aatatgggag attttataaa ctttttagga aataacctcg ccgacttctg
     3781 gacatacacg ggctttgcaa atgctactgt agggcatgtc gttatgattc ttgtgggttt
     3841 ggggttcatc tatctggcgg tagccaaaga gttcgaaccg atgctgctga ttcctatcgg
     3901 cttcggtatg ctgatcggta atataccttt taatatggat gccggactga aagtcggtat
     3961 ttatgaagaa ggttccgtat tgaatatatt gtatcaggga gtaacttccg gctggtatcc
     4021 gccgctcatc tttttgggca tcggcgccat gacggacttc tcggcactta tctctaatcc
     4081 gaaattgatg ctgattggtg cagctgcaca gttcggtatc ttcggtgcat atatgatcgc
     4141 gttagaaatg ggcttcgatc cgatgcaagc cggtgctatc ggtatcattg gtggagcaga
     4201 cggcccgacg gccatcttcc tttcttccaa gctagcacct aacctgatgg gagccattgc
     4261 ggtgtccgcc tactcctata tggcgttagt tccggtgata cagccgccta tcatgcgtct
     4321 gctcaccacc aagaacgaac gtgtcatccg catgaaaccg ccgcgtgccg tttctcacac
     4381 ggagaaggtg attttcccga tcatcggttt gttgctgact tgtttcctgg ttccttccgg
     4441 tctgcctttg ctgggtatgc tgttcttcgg taacctgttg aaagaaagtg gtgtaacccg
     4501 ccgtttggct aatactgcca gtggtccgtt gattgataca atcactatcc tgttgggtct
     4561 gacagtaggt gcttctacgc aagcttccga attcctgacg ctcgactcta tcaagatctt
     4621 tgctctcggt gcattgtcat ttgttattgc aactgcctcc ggtgtcatct tcgttaagat
     4681 cttcaatatc ttcctgaaga agggtaataa gatcaatccg ttgatcggta atgcaggtgt
     4741 ttctgctgtt cccgactctg cacgtatctc acaagtgatt ggtttggaat atgattcgac
     4801 caactatttg ctgatgcacg ctatgggtcc gaacgttgcc ggagtgatcg gttcagctgt
     4861 tgctgccggt attctgcttg gattcttgat gtaagaaaca ttatataata gataagaaca
     4921 cccgtgttac attcagttgt gacacgggtg ttctttatta cagccatagt gttatcttct
     4981 ctccgttctg aaacgattaa acgtcataaa aaaggctgct accagtgttc aaaccggagc
     5041 agcctctttc ttttatttat ggaataatcc ggagattatt actgtgccaa tttgttgtca
     5101 gaaccgagca cgttgatgat tttgtgcttg tacagttttt ccatattgtc acgagccggg
     5161 ccaagatact tacgtgggtc gaattcagcc ggtttttcag cgaatacctt acgtacagca
     5221 gcagtcatag ccagacgaga gtcagagtcg atgttgattt tgcaaacagc agacttagca
     5281 gctttacgca attcttcttc cggaatgccg atagcagctt tcagtgcacc accatatttg
     5341 ttgatagttt ccacttcttc ttccggaact gaagatgatc cgtgaagaac gatagggaat
     5401 cccggaagtt tttccattac agcgtccaat acttcgaaag ccaatggagg aggaaccata
     5461 cggccagtct tcgggtcgat gtggcattgt tccggagtaa acttgtaagc accgtgagaa
     5521 gtaccgattg agatagccaa agagtcgcaa ccagtgcgag tagcgaagtc gattacttct
     5581 tcagggtcag tatatgtgtg gtggtcagca gaaacttcat cttctacacc agccaatacg
     5641 ccaagttcac cttctacagt tacgtcaaac tggtgagcgt attcaacaac tttcttagtc
     5701 aatgctacgt tttcttcgta aggaaggtga gaaccatcga tcattactga agagaaacca
     5761 gaatcgatac aagatttgca agtttcgaat gtatctccgt ggtcaaggtg aagaacgatt
     5821 tccggatgtg cgcagcctaa ttctttagca tattctacag caccctgtgc catgtaacgc
     5881 aacaaagtag cgttagcata ctgacgagca cctttagaaa cctgaagaat cacaggagat
     5941 ttagtttcaa cagcagcctt gatgatagcc tgcatttgtt ccatattgtt gaagttgaat
     6001 gctgggatag catatccacc tttgatagcc ttagcaaaca tttctcttgt gtttaccaat
     6061 cctaaatctt tgtaatttac cattttgttt aaagtttatt gttagtgaat aaaaattcta
     6121 cgcaaaagta agcattatcc
//
