LOCUS       c00007_gnlPro..        13733 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IHDDCAHM_7.
ACCESSION   c00007_gnlPro..
VERSION     c00007_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 10:46:20
            Original ID  :: gnl|Prokka|IHDDCAHM_7
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13733
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13733
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[243:3733]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      244..3733
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13733
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13733
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             3..230
                     /locus_tag="ctg7_1"
                     /transl_table=11
                     /translation="RRKMGPSLSDGACLGFVRHFQVRSPGLLEPFRCNNFLRCATMRKQ
                     LSGILFLVQGNLVMKKLPTADAAGSFYRAS"
     CDS             complement(244..1074)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.6; E-value: 9.2)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_2"
                     /sec_met_domain="Fer2_3 (E-value: 1.9e-23, bitscore: 74.1,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 6.1e-11, bitscore: 34.2,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.3e-06, bitscore: 19.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LPSAATSKDSQYINTQKKDYNMAKTLNLTLKVWRQENREAKGRIE
                     TYAAKDIPVDASFLEMLDIVNEGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPER
                     QVTTCQLHMRKFKDGDTVWIEPFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAP
                     NANNIAVEKVKADAAFDAAACIGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSK
                     RVLAMMKQMEAEGFGNCTNQYECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(1052..3010)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.9e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 8.3e-38,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             complement(3032..3733)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_4"
                     /sec_met_domain="SucD_FumR (E-value: 1.8e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             3934..4206
                     /locus_tag="ctg7_5"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAVKAACGAPNLSK"
     CDS             4209..5024
                     /locus_tag="ctg7_6"
                     /transl_table=11
                     /translation="MMAFIEPHIHMVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSAD
                     GFRDYFVQLTECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLG
                     IGEIGLNRNTSHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLD
                     PCRVLVDHCEEHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADW
                     GDSDPLALTALACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(5058..5291)
                     /locus_tag="ctg7_7"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(5721..6428)
                     /locus_tag="ctg7_8"
                     /transl_table=11
                     /translation="MNKLLSTLILSAGMSLSATAATALLDSSIVGYSDFASQTADFGTR
                     KDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPETYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYSGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYS
                     NSGLKFGNQQINQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             complement(6459..6548)
                     /locus_tag="ctg7_9"
                     /transl_table=11
                     /translation="MNYKYNILTLNIFNCLRIPNSLFKHKYIH"
     CDS             6753..7463
                     /locus_tag="ctg7_10"
                     /transl_table=11
                     /translation="MGSFAVSSEAATVFNYYTPGTDNYNSTIHGFYLGLGSSSLAPSDS
                     SSPSSLSGEIRLDSFTLRGAANNLGANVTYGFLVLNGSDNSVIGWSTNTGTTAAGINLT
                     FSFSSLDGSPLLLDAALTYRFLAVSQSVMDLMQDTSKTYLYAAGGTAAPTANTEGDTVT
                     ISGGLTAPGIRGHYDAEGAPGDSVVITGANGTNTFSLLSPIFTEIRGEMVPEPATVSLG
                     LLGLAALMMRRRRA"
     CDS             7556..7771
                     /locus_tag="ctg7_11"
                     /transl_table=11
                     /translation="MRDSCPPEGTEFPGAGGRIRFSPHGGNLLETFLRRNTGKLFLYRK
                     MPVKFGSALFVHMVHGSFHIAAFQAG"
     CDS             7913..8098
                     /locus_tag="ctg7_12"
                     /transl_table=11
                     /translation="MTDVASTMFPDDAAAVDGDCIQLRDEGRTDAHDMEQVMFIAAGDE
                     IVSERFSRDMFRFGMV"
     CDS             complement(8142..9347)
                     /locus_tag="ctg7_13"
                     /transl_table=11
                     /translation="MRGIFLVSCFLGGSALLAGCREENNSPRPATEDAARITSARQWGE
                     SRSALQKRELDRAAGPALPIPDDLPSRELVGTTRQIHQLIEASGNPARFESYTETVPAA
                     GASLRMVAIPGGTFLMGSPAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFMENG
                     RPRAKDGQLLEEQPDDELWDSVTQPTAPYAAMNLGMGHGYEHGLPAISMSHHAASKFCE
                     WLSAQTGHYYRLPTEAEWEYACRAGSAGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSK
                     KPNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPAKDPLVIIPGAPHIVRGGSWEDDPD
                     SLRSAARRASTPAWNRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDIMTMHRLWNFSKG
                     EP"
     CDS             complement(9371..10300)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_14"
                     /sec_met_domain="adh_short_C2 (E-value: 3.5e-75, bitscore:
                     244.0, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTGRPPVHSGKMKRPDSSPPPRFSPLFFHSRHALSPYGFLRGQV
                     HFKLAGTVKNGFTVGSMQKLAGKTAIVTGAGRGIGNAVARRFASEGARVILISRSPSSC
                     GGAAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFPQIDILVNNAGITRDSLMLR
                     MKEEDWDAVLDTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQANYAASKA
                     GLIGFTKSLAQEFAPRKVTCNAIAPGFISTEMSNAIPDNLKEEIVKKIPLKEQGSVEDI
                     AALTAFLASDDARYITGQVIACDGGMTM"
     CDS             complement(10245..10763)
                     /locus_tag="ctg7_15"
                     /transl_table=11
                     /translation="MKAFLVPLLYSALLSGASLAFGETAAGTASPAAAAPAEKIPSAES
                     LINQAFSFAINIQQTLAGVQDKESADNAVKTLQDIQKDIRHFLQLQDKLNDAEKEKEDA
                     LIEKMKKRMEMLDNRCRQEGKRLFEARYYGSAALKDILENSDEFSDLVEPDEDGAPPGA
                     LRENEEAGQ"
     CDS             complement(10827..12350)
                     /locus_tag="ctg7_16"
                     /transl_table=11
                     /translation="VALVGPNGAGKSTLFRMILGEDTPDEGSISMDEYAIVGYLPQEAS
                     EPKDETVLEIALGITPEMEQAIHTIRTAENANKTDTPEYAEAIDTFNAANGYQLEPKAK
                     KILKGLAFRESDFHRPAREMSGGWIMRAYLAKLLVLEPDLLMLDEPTNHLDLLSLLWLQ
                     RYLKNYPGAILMISHDRDFMDELVESVYDIDNEELVEYRGNYSDFLQQKDVRFEQLQAA
                     YRNQQKEIAHIQEFIDRFRSINSKAGQVQSRIKQLEKMKIIQKPVARRKVFKFNFPQPP
                     RSTQKVIELEKVCQSYGDRRVYENLDLLVERGERTVLVGPNGAGKSTLLKILAGIIPID
                     SGQRTPGTTTRIGYFSQARTENLNPENTVLEEIMKCSAEIREEEARSILGSFLFRRLDV
                     EKRVSVLSGGEKSRLSLVKFLVDPPNLLLMDEPTTHLDLLSVEALVQALKHYEGTLVFI
                     SHDVHFIRSLAQKTLHVNRGTITAYAGGYDYYLEKSGILDDEKGGITAK"
     CDS             12677..13267
                     /locus_tag="ctg7_17"
                     /transl_table=11
                     /translation="MSGLANAFLALLPPDQASLPAAGAEARWLADTAVVQSAAIARDNR
                     TVLFGWLNNILVNSNLRDRGLCWQVQQDLYRDLRRRPVKYFRIGLTIRDRGTGREHSCV
                     YVNAAGKGLQGSIVLDAWKNCGHLVTLTQKDREGGKWEEDWREPFVSKAFPEGHSYGME
                     HHLVWPGWARKRPMLVQRIFQSDQQNEAKAAAE"
ORIGIN
        1 ctcgaagaaa gatggggccg tcgctgtcgg acggggcctg cttaggtttc gtccggcatt
       61 tccaagtacg gtctcctgga ttactggaac ccttccggtg taacaatttt ttacgctgcg
      121 cgacgatgag gaagcaactg tctggtattt tattcctggt tcaaggaaac ctggtaatga
      181 aaaaactccc gacagccgat gccgccggga gtttttacag agcgtcttaa gaaggaatct
      241 tctttagaaa cagaggcctt ccttggcgtt ggcccgcatg aagtcgcggt tgaggcgggc
      301 gatgttgtcc acgctgatgc ctttcgggca ggcggcttca cattcatact ggttcgtgca
      361 gttgccaaag ccttccgctt ccatctgctt catcatggcc aggacgcgct tggaacgttc
      421 cggctggccc tgcggcagca gattgagatg ggcgatcttg gcggaggtga acagcatggc
      481 ggaggcgttt ttacaggagg ccacgcaggc gccgcagccg atgcaggcgg ccgcgtcaaa
      541 ggcggcgtcc gccttcactt tttccacggc gatgttgttg gcgttcggcg cggaaccggt
      601 acgcacgtca atatagcctc cagcggcgat gatgcggtcc agggcggagc ggtccaccat
      661 caggtcccgc aggattggga aagccttcgc gcggaagggt tcaatccaga cggtatcgcc
      721 atccttgaac ttgcgcatgt gaagctggca agtggtcacc tggcgttccg gcccgtgggg
      781 aatgccgttg atggtcaggg agcacatgcc gcagatgcct tcccggcagt cgtggtcaaa
      841 atggatgggt tccttgcctt ccttgaccag gccttcattg acgatgtcca gcatttccag
      901 gaaggaggcg tccaccggaa tgtccttggc ggcataggtc tcaatgcggc ccttggcttc
      961 ccggttttcc tggcgccaga ccttgagagt gagattgagt gttttagcca tgttataatc
     1021 tttcttttga gtgttaatgt attggctatc tttacttgta gctgcggatg gcaaggtgca
     1081 cgttctcgaa ggtcagcggt tccttgtgga gaacaggcag gctgtccacg ccagtgtatt
     1141 cccaggcggc tacataggcg tattcatcgt cgttgcgctt agcttcgccg tccggcagct
     1201 ggtattccac gcggaagtgg gcgccgcagg attcctggcg gttcagggcg tcatagcaga
     1261 gcagctgggc gaattccagg aagtcggcca cgcggcaggc tttttccagt tccgcgttga
     1321 tgccgtccgc cgtgccggtt acgcgcacgt tttcccagaa ttccttgcgg agctggggaa
     1381 tgcgttcaat ggcgtgggtc aggctttctt ccgtgcgggc catgccgcag tcttcccaca
     1441 taatgaggcc cagttcccgg tggaaggagt ccaccgtctt ggtgcccttc acattcagga
     1501 gcttgttgat gcgttccttc acttcgtctt ccgcagcctt gaattccggg gcggcggtgg
     1561 tgacggcgcc gggtttggtg gtcgtcaggt aagcgggcag cgtggcggga atgacgaagt
     1621 agccgtcaga caggccctgc atcagggcgg aggctcccag gcggttggcg ccgtggtcgg
     1681 agaagttggc ttcaccgagg acgtgcagcc ccttcacatt ggacatgagg ttgtagtcca
     1741 cccacaggcc acccatggtg tagtgggagg cggggtagat catcatgggc gtttcatggg
     1801 ggtcgtcgtc cgtgatttct tcgtacatgt caaacagatt gccgtattgg ccgtcaatcc
     1861 attcgcggcc catgcgcttg atttcatccg caaaatctag gaagacgccc ttgccggtga
     1921 cggccacgcc gcggccgtcg tcgcaggctt ccttggcggc gcgggaggaa atgtcgcgcg
     1981 gagccaggtt gccgaaggag ggatacttgc gttccaggta gtagtcccgt tcttcttcgg
     2041 gaacatcgga aggcttgatt tccttcttac ggattttttc tgcggtttca cgggacttgg
     2101 gcacccagat gcggccgctg ttgcggaggg attccgacat cagcgtcagt ttggactggt
     2161 agtcgccctt gaccggaatg caggtggggt ggatttgcgt gaagcagggg ttggcgaaga
     2221 aggcaccgcg cttgtaggcc ttgtaggcgg cagtgacgtt gcagcccatc gcgttggtgg
     2281 acaggaagaa cacgttgccg tagccgcccg tgcagagcag gacggtatcc cctgcgtagg
     2341 atttgatttc gccggtaacc agattgcggg tgacgatgcc cttggcttcg ccgtccacca
     2401 gcaccagatc catcatttca tggcgggaga acatttcaat gtgtcccttg gccacttcct
     2461 tttccagggc ctggtaggca cccagcagga gctgctggcc cgtctgtccg cgtgcgtaga
     2521 aggttcgctt gagctgggcg ccgccgaagg agcggttgtc cagcaggccg ccgtattcac
     2581 ggccgaaggg aacgccctgg gccacacact ggtcaatgat gttggaggag acttccgcca
     2641 gacggtagac attggcttca cgggcgcgga agtcgccgcc tttaacggtg tcgtaaaaca
     2701 ggcggtaaac ggagtcgccg tcattctggt agttcttggc cgcgttaatg ccgccctggg
     2761 ccgcaatgga gtgggcgcgg cgggggctgt cctggtagca gaagcatttg acgttgtagc
     2821 caagttcggc aagcgtggcg gcagcggagg cgccagccag gccggaacct accacaagca
     2881 ccgtgtactt gcgcttgttg ttcggattga tcagtttgga ctcaagtttg tacttggacc
     2941 atttgtcctg aatagggccg gagggaattt tggcatccgg catccagtcg cttacgggaa
     3001 aattaatcat gactttgaga ggagttgatg gttatttgat gatacccaga agaaccgaga
     3061 ccggcacgga gatgaagccc aggcagataa tcgcgccgta ggcgatggcg ataaagttgt
     3121 agaagggccg gattttgcgg gaatcgacgc ccacagtctg gaagatggac tgtaccccgt
     3181 ggcgcagatg gctgaacagc atcagaacgg ccaggatgta gaaggcggag caccatacgt
     3241 tggagaatcc ggtcacgatc atcttgtaca cgtcaaaggt ttccaccgta ccgtcggaaa
     3301 tgaaggtggt gaactgggcg gggtcgtatc ccacgcgcag ggtgtactgg tacaggtggt
     3361 agatcaggaa caccaagacg gtcaggccgg tatagatcat gtagcgggag gagagcgtcg
     3421 ccttgatggt gttcttgaac acgtagggtt cgcgggccgc atggttttcc agcttcagct
     3481 ggatggtcag ccagacgtgg atgatgaaga tcaccgcaag ccccgcgcgg attccccaga
     3541 gggctgcttc cggcatggag tgcaggccgt gggcgtaggt gttgatccat tcagggcctc
     3601 cgaagatgag aaggttgcct gccaggtgtc ccgcaaggaa caagaccaaa cataaccccg
     3661 tcagagccac aatgattttg cggccgatgg aggatgtcac gaatgtacat atggttttta
     3721 ctagtgcatt cataggcgct ctaatgaaat aaatgcgtct tcacaggatg cccggttcaa
     3781 gcccggatgg caagcctctt cttgaatttc cggcgctttt cggatttttg aaaaaccggg
     3841 gaaagaggtt gctgtttatc agtttggaat ggttatcatt ttgttgcctg ttccggcttg
     3901 acgaggcttt ccgcataggc gtatcgtctg tgcatgaaaa gaagtaaaaa ggaggtgctg
     3961 gacgcggatt tcgcagcggc gcgcgccggc gttctggatg tggccgcatt tctggaccgg
     4021 gtggaccgcg gggaagggga ggcggatttc cgctaccatg ccctgatgga tgttcttccc
     4081 ctcttgtccg catccggccc cggacgcgtc cgggccattc tggaagccct ttcctacagg
     4141 gatgacaccg tgccggaaac cgccgcagtc aaagcggcct gcggagcccc gaacctcagc
     4201 aaataagaat gatggctttc atagaacctc atatacatat ggtgtgccgc accacggacg
     4261 aataccgggc catggcgcag gccggctgcc tggcggtagg ggaaccggcg ttctgggccg
     4321 gttacgaccg ttcgtccgcg gacggtttcc gggattattt cgtacagctt acggaatgcg
     4381 aacccgccag ggcggccaag ttcggcatgg accattacac atggctgtgc atcaatccca
     4441 aggaggcgca ggacgtggct ttcgcgcggg atgtgatgaa actgattccg gagttcattg
     4501 accggcccaa tgtcctcggc atcggggaaa tagggctgaa ccggaatact tcccatgaaa
     4561 tgactatttt tgaagagcat ctggatctgg cggtgcgcct caaccagctt gtgctgattc
     4621 acactcccca tctggaagac aagcttaagg ggaccgtaat gattctttcc gccctgaaaa
     4681 accgtccgga tctggaccct tgccgcgtgc tggtggatca ctgtgaggaa cataccttcc
     4741 cgctggtgaa ggaggccggt tactgggccg ggctgaccct ttatcccacc agcaagctga
     4801 atcccaagcg ggcggcggat attctggaat tgtacggaat ggaccgtgtc tgggccaatt
     4861 ccgcggcgga ctggggggat tccgatcccc tggcgctgac ggccctggcc tgcgagctgc
     4921 gcaggcgcgg tttttcccgg caggaaacgg aacgtcttct cctggaaaat ccggagacat
     4981 tcatgggaca gtccccgaag ttccggaaag tgtcgtcccg ctaattccgc ccgaggcgcg
     5041 gcggagggta cggccctcta gtccccgtcc gggaaaaaga cggtgaggac ggcgcccagg
     5101 atgaccgccg cgtcatccag aaggcccagc ctgccgattc cgtcaaacag gaattcgtcg
     5161 ggagtcagga tgtaggcgcc ggcggcggcc agaaggcata tattccgttt gttgaaaaaa
     5221 cgcggttctc cttttctgct tttgaaatac cggaacaggc gcagtagcag ctgctgtttt
     5281 tgaaggttca tggatgggaa cgggggataa aggttcaagt tcagccattt tcccactcct
     5341 tttccctgtt tcagggaagg agtctgttgc cgacggacgg aaaccgcagc gatccggacc
     5401 gtgcggggaa atggattgct gaaaggatgg gctgttccgg atgctgaggg aagccgggct
     5461 ttgcatgctc cggttccggc tgtcccggca tgggaaaaag gggcgtgtac ggaagtgggg
     5521 cggggccgga agctcttgaa atgaccctcc cgggggagcc tgaatgccat ttccccgtca
     5581 agtgctggcc gtgagggtac ccagcaaata gaagcttctt ccccctgttt tttccggcag
     5641 atgtttgaac ggataaggaa aaggccggct cacgattttg tgagccggcc tttgaatata
     5701 gggaggcgga cggtacaggc ttatgccctg cggcggcgca tcatcagcgc ggccagtccc
     5761 agcaggccca gggaagccgt ggcgggttcc ggaatgctgg cgatttcact catcagctga
     5821 ccaacttgtt cctgggaaag gagggagtcg tggatgtaga gctgttcgat ggattcagcc
     5881 agtcctgcgt ccatgagaat ctgattaatt tgctggttgc cgaatttcag gccgctgttg
     5941 gaatagtacg tagcgctgtc tccaaaatag atgcgggtgc caagatctcc ggtgactacg
     6001 gaaatggtca gggaaccttc cgtgcccagc ggggtgtcaa cgacgggccc gctgtatgag
     6061 gtgttgttcc ataatccctg gagtttccgg tccgtgttca ggcccacgcc ccagcttaca
     6121 ctgctgtttt tggcgttaaa cagagcggta taggtctccg gagtgttgat tttggacagg
     6181 tcaagaacca tcgtcacaga cataacgtcg cggttgttgg caccgtatcc gttgaaggtt
     6241 atcccggaca acgtcagatt gctgtcgtca gacgtgatgg aaacggaatc tttccgggtg
     6301 ccgaaatccg ccgtttggga ggcaaagtcc gaatatccca cgatggagct atccaacaga
     6361 gcggtagccg cggtagcgct caggctcatg ccggccgaaa gaatcagggt ggataataat
     6421 ttattcatgg tcagtatctt aataaaatga ttcaaggttc aatgtatgta cttgtgcttg
     6481 aataacgaat ttggaatccg caagcaatta aaaatattaa gagttagtat attgtattta
     6541 taattcattg aaaataatga ttttttaata tctctggtcc ttttgtcaag atgacgggtc
     6601 agtctttgtt attcattggt ttcatgattg atttggcctc tttttcatta cttgacggat
     6661 tccaaatccg attggggaat tccaaattcg ctacaagttg ccatccaaaa ggaataataa
     6721 atatgaagaa aacactgaca tttttaatcg cgatgggaag ctttgctgtt tcctcggagg
     6781 cagcgaccgt ttttaattat tacactcccg gtacggataa ttacaatagt accatccatg
     6841 ggttttatct tggcctgggg tcttcttccc tggctccttc cgattcctct tctccctcct
     6901 ccctgtccgg agagatcaga ctggacagtt ttacgctgcg cggagccgcc aacaatttgg
     6961 gcgctaatgt cacttacggc ttcctggtgc tgaatggctc cgacaattcg gtcatcggct
     7021 ggagcaccaa tacgggaact actgcagcag ggattaatct gacgttcagt ttttcttccc
     7081 tggatggttc tcccctgctt cttgacgcgg cattgacata ccgtttcctg gccgtgagcc
     7141 agtccgtgat ggacttgatg caggatacgt ctaaaacgta tttatatgct gcggggggaa
     7201 cagccgcccc tactgctaac acggaaggag ataccgtaac gatcagcggt ggattgactg
     7261 ctcccggcat ccgcggccat tatgacgccg agggagcacc tggtgattct gtcgttatta
     7321 cgggagccaa cggaaccaat actttcagct tattatcccc gattttcacg gaaatccgag
     7381 gggaaatggt gccggaacca gccacggttt ccctgggcct gctgggactg gccgcgctga
     7441 tgatgcgccg ccgcagggct tgagcttcct gatggcgaaa aatcggcgga tgagagctgt
     7501 tcttgcggaa cagctcttgt tttttatatc cagagaggaa gaattgctta tccgtatgcg
     7561 ggattcatgc cctccggaag gtacggaatt tccgggggca gggggccgta tccggttttc
     7621 tccgcatggc ggcaatttgc tggaaacgtt tttgagacgc aataccggaa agctttttct
     7681 ttaccggaaa atgccggtca aattcggcag cgcgcttttc gtccatatgg tacacggcag
     7741 cttccacata gcggcctttc aggccggata gggaacccct ttgcagcgca cagacctgga
     7801 gggccgccgc atacctatta tccgccgtcc tattccccgg cgctggtatt ccggaagaac
     7861 ggcaatgggc cccatgccca gcacttcata ttcttttcca tcgtctgccc tgatgacgga
     7921 cgttgcatca acgatgtttc ccgacgatgc ggctgccgtg gacggcgact gcatccagct
     7981 ccgggatgaa ggaaggactg acgcgcatga tatggagcag gtaatgttca ttgcagccgg
     8041 ggacgaaata gtttcagaac gcttctctcg tgacatgttc cgtttcggca tggtctgagg
     8101 attgttccgt tcttaatgca atggtcatga aagattgttc tttacggctc ccccttggag
     8161 aaattccaga ggcggtgcat cgtcataatg tccggaatgt tcatggggcg caccacgcgg
     8221 aacccgatca tgcctccgtc cgtcaggtac cagatgcttt tagggttttg aggatcctga
     8281 cggttccagg cgggggtgct ggcgcggcgc gcagcgcttc tcaggctgtc cgggtcgtct
     8341 tcccacgaac cgccgcgaac gatgtgaggg gcgccgggga tgatgaccag ggggtctttc
     8401 gcgggcaagc cgctccgttt gccgtaggca tccggaacgt aagagtccaa aacccattcc
     8461 gccacatttc cgtgcatgtc ccggagtccc cacttatttg gttttttaga gcctgttttc
     8521 tggtagcggt cattggaatt gttccagtac caggcgtact ggtccagaga ggcttccccg
     8581 tttccgtaag aataggcgcc ggcggaaccg gcccggcagg cgtattccca ttccgcctcc
     8641 gtgggcaggc ggtagtaatg cccggtctgg gcgctcagcc attcgcagaa tttgctggcg
     8701 gcgtggtggg acatggagat ggcgggcagg ccgtgttcat agccgtggcc catgcccagg
     8761 ttcatggcgg cgtagggggc ggtaggctgc gtgacggagt cccacagttc gtcatccggc
     8821 tgttcctcca gaagctggcc gtccttggcg cgcggacgcc cgttttccat gaaggccgta
     8881 taaagttccc aggggatttc cgtttccgag atccagaagg gagagatgct cactttatgc
     8941 tgcggacctt cgtccggttt ccggtgcggc tcttccgcgg gactccccat gaggaacgtt
     9001 cctcccggta tggcgaccat gcgcagggaa gctcccgccg cgggaaccgt ttccgtgtag
     9061 gattcaaaac gtgccggatt tccggaagct tcaatgagct gatggatttg gcgcgtcgtg
     9121 ccgaccagct cccgggacgg caggtcatcc ggaatgggaa gggcaggacc ggcagcgcgg
     9181 tccagttccc gtttttgcag cgcggatcgg ctttctcccc actggcgtgc gctggtaatg
     9241 cgcgcggcat cttccgtggc cgggcggggg gaattatttt cttcccggca cccggccagc
     9301 agggcgcttc ctcccagaaa gcaggaaaca aggaaaatgc cgcgcatgga atggtgaaaa
     9361 ccggaatgcc ctacatcgtc atgcctccgt cgcaggcaat gacctgcccg gtgatgtaac
     9421 gggcatcgtc agaggcaagg aaggccgtca gggcggcgat atcttccacg gaaccttgtt
     9481 ctttcaaagg tattttctta acgatttctt ccttgagatt gtcgggaatg gcattggaca
     9541 tttccgtgga gatgaagccg ggagcaatgg cgttgcacgt gactttgcgc ggagcgaatt
     9601 cctgagccag tgatttggtg aaaccgatga ggcccgcctt ggaagcggcg taattagcct
     9661 ggccgatgtt gccgacgaga ccgatgacgg agctcatgtt gatgatgcgc ccggccgggg
     9721 atttcatgag aacgcgctgg agggccttga ccgtattgaa cgcgcttttc aggttggtgt
     9781 ccagaacggc atcccagtct tcctccttca tgcggagcat cagggagtcc cgcgtgatgc
     9841 cggcgttgtt caccaggatg tcaatctgcg ggaagtcttt caaaatggcg gccatggttt
     9901 cctgaacggc cgcgtaatcc gctacgtcgc aggggtaggc cttgcaggaa tccggaaatt
     9961 ccttgttgat ttcttctgcg gcccccccgc agctggatgg actgcggctg atcaggatga
    10021 ccctggctcc ttccgaagcg aagcggcgcg cgacggcatt gccgattccg cggcccgcgc
    10081 cggtaacgat ggctgtttta cctgctaact tttgcatgct gcccacagta aacccgtttt
    10141 tcacggttcc ggcaagcttg aaatggactt ggccgcgcag gaacccatac ggggaaaggg
    10201 cgtgccggga atgaaaaaag aggggggaga aacggggcgg ggggctactg tccggcctct
    10261 tcattttccc ggagtgcacc ggggggcgcc ccgtcttcat ccggttctac caggtcgctg
    10321 aattcatccg aattttccaa aatgtccttt aaggcggcgg aaccgtaata gcgggcctca
    10381 aacaggcgtt tgccttcctg cctgcagcgg ttgtccagca tttccattcg ttttttcatt
    10441 ttttctatca aggcgtcttc tttctccttt tccgcatcgt tcaatttatc ctgaagctgg
    10501 aggaaatgcc ggatgtcctt ctgaatgtcc tgcagcgttt tgacggcgtt gtccgcgctt
    10561 tccttgtcct gaacgcctgc caacgtctgc tggatattga tggcaaagga aaaggcctgg
    10621 ttgatcaggg attccgcgga aggaattttt tccgccggag ccgctgctgc gggggaagcc
    10681 gttccggcgg ccgtttcacc aaatgcaaga gaggctccgg acagaagcgc agaatataag
    10741 agaggaacaa gaaaagcctt catcctgttc ttttaaggca ggatgaaatc cacggcaagg
    10801 aaaaagggga aactgaaaaa agagccttat ttcgccgtga tgccgccttt ttcatcgtcc
    10861 agaatgcctg acttttccag atagtagtca tatccgcctg cgtaggcggt gatggtcccc
    10921 cggttcacat gcagggtttt ttgtgccagg gaacggatga agtgcacatc gtgggagatg
    10981 aagaccagtg ttccttcata atgcttcaga gcctgcacca gggcttctac ggacaaaagg
    11041 tccaggtggg tggtcggctc gtccatcagc aggaggttgg gcggatccac caggaatttg
    11101 accaagctga gccgcgattt ttccccgccg gaaagaacgc tgacgcgttt ttccacatcc
    11161 agcctccgga acaggaagga acccaggatg gaacgcgctt cttcctcccg gatttcagcg
    11221 ctgcatttca tgatttcctc cagcacggta ttttccggat tcaggttttc cgttcgcgcc
    11281 tgggagaagt agccgatgcg cgtcgtggta ccgggagtgc gttgtccgga gtcaatgggg
    11341 atgatgcccg ccaggatttt gagaagagtg gatttgcccg cgccgttcgg gcctacaaga
    11401 acagtgcgct ccccgcgttc caccagcagg tccaggtttt cataaaccct gcggtcgcca
    11461 taggattggc agactttttc cagctcaatg actttctggg tgctgcgcgg aggctggggg
    11521 aagttgaatt taaatacttt cctgcgggct accggttttt gaatgatttt catcttttcc
    11581 agctgcttga tgcggctctg gacttgcccg gctttggaat tgatggagcg gaaacggtca
    11641 ataaattcct gaatgtgcgc tatttccttc tgctggttgc ggtaggccgc ctgaagctgc
    11701 tcgaagcgca cgtccttttg ttggaggaag tccgagtaat tgccgcggta ttccaccagt
    11761 tcttcgttgt cgatgtcgta cacgctttcc accagctcat ccatgaaatc ccggtcgtgg
    11821 gaaatcatca ggatggctcc ggggtagttt ttcaggtatc gctggagcca cagcagggac
    11881 aggaggtcca ggtggttggt aggttcgtcc agcatcagga ggtccggctc caggacaagg
    11941 agcttggcca ggtacgcgcg catgatccag ccgccggaca tttcccgggc ggggcggtgg
    12001 aagtcgcttt cccgaaaggc cagccctttg agaattttct tggctttggg ctccagctgg
    12061 taaccgttgg cggcgttgaa ggtgtcaatg gcttccgcgt attccggcgt atccgttttg
    12121 ttggcgtttt ccgccgtccg gatggtgtgg atggcctgtt ccatttccgg cgtgatgccc
    12181 agggcgattt ccagaacggt ttcatccttc ggttcgctgg cttcctgggg aagatagccc
    12241 acgatggcgt attcatccat gctgatggag ccttcgtccg gcgtgtcttc tcccagaatc
    12301 atgcggaaca gggtggattt gcctgctccg ttggggccaa ccagagccac ccgttccccc
    12361 cagttaatgg tcatttccgt ttccctgaac aaggtccgtc cggcgtggga ttttgtgaga
    12421 tttttgatcg tcagcatggt gaagagagga tgtattctac cgggatggaa aggggaaggc
    12481 aagagccgtc agggcggagg caggcatttt tgaaagcttt actggatttt tacgcgtagt
    12541 ctgctagcct tggcgcgcca tgccgaccac gcagacattc aggcttttgc ttgctgccgc
    12601 ccttttgtgc ggatggagtt cctgctgtac tcctccggcg gaggattata tacaacaacc
    12661 ttacgtgcag cagcaaatgt ccgggctggc taatgccttc ctggcgctgc tgccgccgga
    12721 tcaggcctct cttcccgctg ccggagcgga ggccaggtgg ctggcggaca cggccgtggt
    12781 ccagtccgcc gcgattgccc gggacaacag gactgtgctg tttggctggc tgaacaatat
    12841 tctggtcaat tccaacctgc gcgacagggg gctgtgctgg caggtccagc aggatttgta
    12901 ccgggacctg cgccgccgcc ccgtgaagta tttccgcata gggctgacga ttcgagaccg
    12961 aggaacgggc agggagcaca gttgcgtgta tgtcaatgcc gcggggaagg gattgcaggg
    13021 ctccattgtt ctggatgcct ggaagaactg cgggcatctg gtgacgctga cccagaagga
    13081 ccgggaaggc ggcaaatggg aggaggactg gcgggaacca tttgtttcca aggcctttcc
    13141 ggagggccat tcctacggca tggaacatca cttggtctgg cccgggtggg ccaggaaacg
    13201 ccccatgctg gttcagcgga tatttcagtc cgatcagcag aatgaggcga aggcggccgc
    13261 tgaataaagg ggaagcctga tccggcagga accggcacac ggtgctgcgc cgcggcggtt
    13321 tgcggtatcc gccgttttta aggaaaatcc cggcgaatcg gcaaatggcg gagggaatcc
    13381 ggactcaggg caaataaaaa cgcactcagt gcgtacaccg agtgcggatt aattggataa
    13441 tttgctagtg ttgcagggca aaaccccgct gcaaacttac ttgcccttgg cctgcacaac
    13501 cggagcggga gcaggagcgg tggtttgctg ttgctgctgc tgctgggagc aggaagcgac
    13561 caggcaagcg gcgccggcga tggcgaggat agcgatgttc ttcataattc gaattaaata
    13621 cagtgtttgt taactactgg aacctccgca tccacggagg tttgctggca ccaatgtaaa
    13681 tggtggcaag tagaaatcaa gagattttct tgttccatgt cacggcatta cag
//
