LOCUS       gnlProkkaCACIEOLF_870  12318 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CACIEOLF_870.
ACCESSION   gnlProkkaCACIEOLF_870
VERSION     gnlProkkaCACIEOLF_870
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 10:53:53
            Original ID  :: gnl|Prokka|CACIEOLF_870
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12318
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12318
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[9855:10206]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      9856..10206
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12318
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12318
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(2..616)
                     /locus_tag="ctg870_1"
                     /transl_table=11
                     /translation="MFEIKVSKEIKDACPVFAGAAVYAAVKNTAYNEGLWQEINAFTRQ
                     LTSTTQMEDIKHQPVIFATREAYKRCGKDPGRYRPSAEALRRRLMRGIPLYQIDTLVDL
                     INLVSLRTGHSIGGFDADKIQGTHLELGIGKAGEPFEGIGRGVLNIEGLPVYRDSFGGI
                     GTPTSDHERTKMDLGTTHILAIVNGYNGKDGLQEAVEMIQTL"
     CDS             complement(667..1320)
                     /locus_tag="ctg870_2"
                     /transl_table=11
                     /translation="MISLTKNNELKGYKSLDVYPEVAHFVTTRHLIINESFFKESLEMR
                     RLLLRGMDALITNVPGYCVCVTTADCVPVLLYDKKQHVVAAVHAGWKGTVKHIVSHVMD
                     HLNQKFGTQGEDVVACIGPSISLESFEVGDEVYDAFKESGFDMSLISMKKKETGKYHID
                     LWEANRIELLNAGVPAEQIEVAGICTYIHHDEFFSARRLGIDSGRILSGIMIRK"
     CDS             complement(1317..2483)
                     /locus_tag="ctg870_3"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKGRSFGKDGADKVIEVPCGTVVYNAET
                     GEYLCDVTEDGQEVILLKGGRGGQGNWHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSSISAAKPKIADYPFTTLEPNLGIVSYHGGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     VTKSDMLDQELMDEIEPTLPEGIPHVFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEDIVYEYDDNVDDDDDDIDYEYEEEDWEEK"
     CDS             complement(2599..3168)
                     /locus_tag="ctg870_4"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMVDLDVPEEELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTAPLIDWYKNE
                     KKYQHINGLGTMEGIFAEICEAVDKL"
     CDS             complement(3236..3772)
                     /locus_tag="ctg870_5"
                     /transl_table=11
                     /translation="MDTIQIKDKQFTVSIKEQDIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGVTSSGVIKEVIGLNEDIAGRTVVIVEDI
                     VDTGLTMQRLLDTLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYLDIYTVVD"
     CDS             complement(3814..4257)
                     /locus_tag="ctg870_6"
                     /transl_table=11
                     /translation="MEPASPTKQAIGLLLLSLGYLFICFGVKDAIPGVKVSMIWLTGLY
                     FIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAGMLSGLYPEAGKVK
                     SIFGYQIATMYDFFMVFVVMSGVASLILFLLSKKLQKMMHGVE"
     CDS             complement(4497..5198)
                     /locus_tag="ctg870_7"
                     /transl_table=11
                     /translation="MSALKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAMMMAVGQFLMFMSASTLDNTE
                     LAHWMMYGGLGFLILGNGCFKPTVSSLVGQLYEPGDRRLDAAYTIFYMGVNVGSFAAPL
                     ICGYLGDTGDPHDFKWGFLAAGIMTLFTVVLFETQKNKYLFSPSGEPIGIIPDAKREKK
                     EDKAEHIWMVH"
     CDS             complement(5403..5627)
                     /locus_tag="ctg870_8"
                     /transl_table=11
                     /translation="MMEKTKIGLNAGKVWRILNEKGELSMFDLCRELSLTFEDVALAIG
                     WLAREDKIFLRKREGMLFASIENVEFTFG"
     CDS             6690..8201
                     /locus_tag="ctg870_9"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPVLTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSEDGIEEMET
                     NYEMLEIEEIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCQTPVVVDADALNILANHRHTLTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
     CDS             8274..9341
                     /locus_tag="ctg870_10"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELTSVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVGKKAAPAPTVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKIPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             9378..9662
                     /locus_tag="ctg870_11"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(9856..10206)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg870_12"
                     /sec_met_domain="PqqD_RRE (E-value: 2.8e-11, bitscore:
                     33.0, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 5.8e-18, bitscore: 55.0,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPAGMSKELHVRLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVA"
     CDS             complement(10304..11692)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 95.3; E-value: 4.9e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg870_13"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGYTDEGGAFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSLMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMTIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             complement(11940..12317)
                     /locus_tag="ctg870_14"
                     /transl_table=11
                     /translation="MLMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRKTTDFLE
                     KATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAPQTEAPA
                     TNAPATETPAPATETPAPAAE"
ORIGIN
        1 ataaggtttg tatcatttca acagcttctt gcaaaccatc tttcccatta taaccgttga
       61 ctatcgccag gatatgagta gttccgagat ccatcttcgt acgttcgtga tcgcttgtcg
      121 gtgttccgat tcctccgaat gaatcgcgat atacgggtaa tccttcaata ttcaacacac
      181 cgcgaccgat accttcaaac ggttctccag ctttgccgat accgagttca aggtgtgtac
      241 cttgtatttt atccgcatcg aaaccaccaa tagaatgtcc cgtacgaaga gacacgaggt
      301 taatcaggtc taccagtgta tcaatctgat atagcgggat tccacgcatc aggcggcggc
      361 gtagagcttc ggctgacggg cgataacgtc cggggtcttt gccacaacgt ttataagcct
      421 cacgggtagc aaagataacg ggttgatgtt tgatgtcttc catctgtgta gtggaagtca
      481 gttgcctggt aaaagcgttg atttcctgcc aaagcccttc gttgtaagca gtattcttca
      541 ctgcagcata cacggcggct ccggcaaaaa ccgggcatgc gtcttttatt tctttagata
      601 cttttatttc aaacataact tatcataaac caatcatcag cgtcctgcaa ttacggacac
      661 caattattac tttctaatca ttattcccga caagatacga ccggaatcta ttcccagtct
      721 acgtgcggag aagaattcat catgatgaat ataggtacag atgccagcta cttctatctg
      781 ttctgcaggc actccggcat tcagtaattc aatccggttg gcttcccaca aatcaatatg
      841 atatttgccc gtctccttct tcttcataga aataagagac atatcgaaac cgctttcttt
      901 aaaagcatca tacacctcat cacctacttc aaatgattcg agcgaaatgc tcggcccgat
      961 gcaagctacc acatcttcgc cttgcgtccc gaatttctga ttcaagtgat ccatcacatg
     1021 actgacaata tgcttcacag ttcctttcca tccggcatga acggcagcca caacatgttg
     1081 ttttttgtcg tacagcaata caggaacaca atccgccgtc gtgacgcaaa cgcaataccc
     1141 cggcacatta gttatcaagg catccattcc tcgcaaaagt agccgtctca tttctaatga
     1201 ctctttaaaa aatgattcat tgataatcag gtgacgcgtt gttacgaaat gagctacctc
     1261 gggatataca tccagtgact tatatccctt caactcatta ttttttgtaa gtgaaatcat
     1321 ttttcttccc aatcttcttc ctcgtattca tagtcgatat catcgtcatc atcatcaaca
     1381 ttgtcatcat attcataaac gatgtcttca tcttcgccca tgtctttgag ctcctgttgc
     1441 agacgggtta cgtccttcgg acggtgaacg atgtcctcta tcttattgct ttccttattc
     1501 agttcttccc aaagaatgtc tttcaacacc gagataccca aaccggaaac agaagatatg
     1561 aatacgtggg gaatgccttc cggcaatgta ggttctattt cgtccatcaa ttcctgatcg
     1621 agcatatcgc tcttggtgac agccaacaca cgttgcttgt ccaacatttc aggattgaaa
     1681 gtacgcagtt cgttcagcaa gacttcgtat tccttacgaa tgtcgtcact gtctgccgga
     1741 accataaaca gcagtaatga attgcgctcg atatgacgca ggaaacgcag tcccaagcct
     1801 ttaccctgac tggctccctc gataataccg ggtatatctg ccatcacgaa agactttcca
     1861 ccatgatagg aaacgatacc cagattgggt tcgagcgtag taaagggata atcggcgatt
     1921 ttcggtttag cagccgaaat ggaagaaagc aaagttgact tacccgcatt cgggaaacct
     1981 accagaccga catcggcaag tagtttcagc tccatgataa cggtcatttc ctgcatcggt
     2041 tctcccggct gcgcaaaacg cggcgcctga cgggttgccg tcttgaaatg ccagttaccc
     2101 tgaccaccgc gaccgccttt gagcaaaatc acttcctgtc cgtcttctgt tacgtcacaa
     2161 agatattcgc ctgtctcggc attataaacg accgttccac agggcacttc tattacttta
     2221 tccgcaccgt cttttccgaa actacgtcct ttgctccccg attcaccatg accggccatt
     2281 gcgtgacggt catatttcaa gtgcagcaat gtccagtaat tacggttacc gcgcaagatg
     2341 atatgacctc ctcttccacc atcgccccca tcgggacctc cgttaggaca atatttctcg
     2401 cgcctcatgt gcgtagagcc tcttccgccc ttacccgagc gacagtatat ctttacgtaa
     2461 tcaacaaaat tcgattcagc catattcttt ttaagtagtt aaagtagtca gtagttagag
     2521 taattaagta gaatcctccg gctactgact gacttattca tttataatag tgtattgata
     2581 attagtaaga ttactaaatt acaatttatc tactgcttcg cagatttcag caaagatacc
     2641 ttccatagta cccaagccgt tgatgtgttg gtatttcttt tcgttcttgt accagtcgat
     2701 cagtggggca gtctgtgaat gatatacgtg cagacgtttt ttgattgtct cttcgttatc
     2761 atcagcacga ccggaatcct taccacgttt aatcagacgt accatcagtt cttcttccgg
     2821 aacatccagg tcaaccatta cagaaacatc ctgtcctctt tctgccaaca ttttctttaa
     2881 tgcttcagct tgtgcaattg ttcttgggaa accgtcgaaa attacacctt tgctatcttt
     2941 gaagctgtcg aatacgcttg ccagaatatc aatcattaat tcatcaggaa tcaattgacc
     3001 ttggtcgatg taacctttag cagttttacc caattctgtg ccattcttga tttcagcacg
     3061 caatacatct cctgttgaga tgtgattgat tccatacttt tctacaatac gttcgctctg
     3121 tgttcctttt cctgaacccg gagcaccgaa aattacgatg ttcaacattt tgttatttac
     3181 aatttaacga tttactattt accattaaaa ctggtaccta tttaatatta actgtttaat
     3241 ctactactgt ataaatatcg agatagttgc gtccgaaacc atcataatcc agtccgtaac
     3301 ctacgataaa gtcgttcggg atttccattg ctacgtattc gatgttcaga ttgaccttga
     3361 gtttttcagg cttcactagc agagaagcaa tatggattgc ttcagggttg cgtgtaccca
     3421 atgtatccaa caggcgttgc atggttagcc cggtatccac aatatcttct acaataacta
     3481 ctgtacgtcc ggcaatgtct tcattcagtc cgatcacttc cttaatcact cccgaagaag
     3541 tcactccctg ataagaagcc agtttcacaa acgaaatctc gcaagggatg gtgatgtgct
     3601 tcaacaagtc ggcagtaaac ataaatgaac cgttcaacac actaaggaag agcggattct
     3661 tacctgccaa gtcgcggttg atttcgttcg ctacgcgaat cacttctttc tgaatatcct
     3721 gttccttaat agaaacagtg aactgtttgt cttttatctg aatggtatcc ataaccggta
     3781 atttaaaaaa taaccttgca aaaatacgat tttttattct accccgtgca tcatcttctg
     3841 taatttcttc gagagaagga acagaatcaa tgaagcaaca ccggacatga caacgaatac
     3901 cataaagaaa tcgtacatgg tagcaatctg ataaccaaag attgatttca cttttccggc
     3961 ttccggataa agtccactca acatgcctgc aaatttattg gctgtggcag tagacagata
     4021 ccagattccc atcatcaaag aggcgaaacg tagcggactc aacttattta ccattgaaag
     4081 tccgataggt gacaaggcta tttcacccat tgtatgaata aagtaaagtc ctgtcagcca
     4141 aatcatactt accttcactc cggggatagc atctttcact ccgaaacaga tgaaaagata
     4201 acctaaagaa agaagtaaca agccaatcgc ttgtttggta ggagaagcag gttccatctt
     4261 tcgtttgttg aggaagctcc acacacccgg cattatatat gccaggacaa caacaaacag
     4321 aggattgaag gattgaaacc acgaagccgg catttcccaa cctaaaatat cacgattggt
     4381 ttgttcggag gcaaagagag ttaaagaggc tcctgcctgt tcgtaagccg cccagaagaa
     4441 aatgacaaag aaagctacta tatagataac gaaaatacga ctacgttcga tcttggttaa
     4501 tgaaccatcc agatatgctc ggctttatcc tctttctttt cacgtttggc atcggggata
     4561 ataccgattg gctctccgga aggagagaaa agatatttat tcttttgagt ttcaaaaagt
     4621 acaacagtga acagtgtcat gattccggct gcaagaaatc cccatttaaa atcgtgcggg
     4681 tcaccggtat cgcccagata accacaaatc aaaggggcgg caaaagaacc tacattcact
     4741 cccatataga agatggtata tgcagcatcc agccgtctgt ctcccggttc gtagagttga
     4801 cctacgagag aagaaacggt aggtttgaaa caaccatttc ccaagatcag gaatccgagt
     4861 ccgccataca tcatccagtg agcaagttcc gtattatcta aagtagaggc actcataaac
     4921 atcaggaatt gtccgactgc catcatcatt gctccccaaa acacagagcg acggattccc
     4981 caatatttat cggcaatgta tccgccaatc aaaggagtta aatagactaa cccggtatag
     5041 ctaccgtaaa tggatgctgc cgcttctttg tcaaacaata atgcctgcgt caggaaaaga
     5101 ataaagatcg cacgcatacc gtagtaactg aaacgttctg ccgtgcttgt cgcgaaaatc
     5161 agataaaggc ctttcggatg ccctttcaat gcactcatga atttatgtgt ttagtagttt
     5221 atggggtgca aaggtacgaa aaatagatta aatgcttcaa aaaaagaaag ttcttatcaa
     5281 acgggaatat agggggaata ataaaaatgg gcataaaaaa tcctactgat ccacttcatt
     5341 atttttttag ctgtgtaaat aacaaagtgg agatccatct taaatatagg ttagctacca
     5401 ccttagccaa aagtaaattc gacattttcg atactggcaa aaagcattcc ttctcttttc
     5461 ctcaaaaaga ttttgtcttc tcgggccagc caaccaatag caagagctac gtcttcaaac
     5521 gtcaaactta attcacggca caaatcgaac attgaaagtt cacctttttc atttaagatg
     5581 cgccatactt tcccggcatt caagccaatt tttgtctttt ccatcatgca aactttagaa
     5641 gattaaacaa tccgttattt agattctaat tcattgtgag cacaggaaat taatgtgatg
     5701 cacattatct atctccaaag ataacatttt tatcggaaac ggcaaataat caaaggctta
     5761 atcaagggaa ccgcattaaa aatttgttta agaaggtatg gagataaact aaacacaatt
     5821 tccatccgcc cctctacaga aaaagatttt tcattttcat ttctcatatt ctcataaata
     5881 aggcacaagt ggcagtaaac taataagata gactatgaga aatgatttta aaacaggcat
     5941 ttctcatagt ttcttcgcaa aataacccgg attttgcttc atttctcata gtgtagtgtg
     6001 ccggaagctg acattgaata aatagaacta tgtattcctt ttgcttgctt ccatacacag
     6061 tgtcttagtc ccacatattg tgggaaaaga ttccctaagg cttgggaaag tatcccctta
     6121 ttttgtggga aagttttcct tcaatatacg agaatacttt cccacaatat atgggacaat
     6181 cgagaacaac gagcatctcc aagcaaaaag ccactatttt atctaaatag tagcttcatt
     6241 tcctgataaa aataaggcag gctgaaagaa aaaaggaaga aagaatggct tttgactatg
     6301 agaaataccc tgaaatacga tgagaataag gtggcttttg agccaaaata tgggagaact
     6361 tatgagaaat accgttttga aaaagtgttt ctcataagat atctatttga ttatctttcg
     6421 tttatcgaaa aacaatgaga atatgagaaa tgaaatgaag aaatcttttt cagggagaaa
     6481 taaaagtaag ttcataatgg tgcagcattg aattattttt tggcggagtt attctaacac
     6541 ttaatagttc aaaagcagat atttctttga ccaaaagata gaactaatga tgaattaaaa
     6601 gttgcaatta tggttttctt cccacaacaa acgggaaaag tcagaagaat catgtacatt
     6661 tgtaatccga aaactaaaag aacatcgcaa tgaaaatatt tccaagcagc agtatcaaga
     6721 aattggacgc ttataccatt gagaacgaac ctattgcatc aatcgatctg atggaacgtg
     6781 cagcaaccgt attaacaaaa gccatcacag acagatggaa tacggaaaca ccggtcacta
     6841 tctttgccgg accggggaat aatggcggag acgctctcgc cgtagcccgc atgatggctg
     6901 aaaaaggata taaaatcgag gtatttctct tcaacacgaa aggagaactt tcacccgact
     6961 gccagaccaa taaagaactg gtagaaatga tggaagaagt aaaattccac gaaatcagta
     7021 cccaattcgt acctcccgtc ctgacgcccg atcatctggt aatcgacgga ttattcggtt
     7081 caggtctgaa caaaccgttg agcggtggat tcgctgccgt agtgaaatac atcaattcct
     7141 cccctgccat ggtagtagcc atcgacattc cttccggact gatgggagaa gaaaatacat
     7201 tcaacgtaaa agctaatatt atccgcgccg acgtaacttt cagtctgcaa ctgccgaagc
     7261 tcgcctttct tttcgcagag aacactgaat ttgtcggaga atgggaagtg ctggatatcc
     7321 aattaagcga agacggtatt gaagagatgg agactaacta cgaaatgttg gaaatagaag
     7381 aaatccgttc actcatcaag ccacgcaaac agtttgccca caaggggaac ttcggccatg
     7441 cactattgat tgccggttca aaaggaatgg caggagcctc tgttctcgct gcccgcgcct
     7501 gcctccgttc gggagtaggg ttgctgactg ttcatgcacc aatgtgcaac aacgacatct
     7561 tgcagacctc catacccgaa gcaatcgtag aaaccgacat caacgaaacc tgttttgccg
     7621 tacctaccga tacggacgac taccaagcag tcggcatcgg cccgggactg ggacgaaacg
     7681 aggaaacgga agctgccttg ttggagcaac tggaacactg ccagactcct gttgtagtgg
     7741 atgccgacgc tcttaatatc ctcgccaacc accgccatac ccttacccac ctgccgaagg
     7801 gttccatcct caccccgcat ccgaaagaac tggaacgtct gaccggcaaa tgccaggact
     7861 cttacgaacg tctgatgaag gcttgcgaac tggcccgtgc cgcccatgtc cacattattt
     7921 taaaaggagc ctactccgcc attatcaccc cagaaggtaa atgtttcttc aacccaaccg
     7981 gaaatccggg aatggcaacc ggaggtagcg gtgacgtact gaccggagta atcctggcgc
     8041 tgcttgccca aggttatccc accgaagaag ccgctaaaat cggcacttac attcacggat
     8101 tggcgggcga tgtcgctcaa aagaagcaag gaatgatcgg aatgatcgca agcgatatta
     8161 tcacctgtct gccgacagca tggcgacttg taagcgaata aaagttaaga acttacagtt
     8221 ttttcaataa cttcattaac tttgttttca aaaccagtta aaaagaaccg aatatgaaaa
     8281 agttgattat agcagcagga ctacttatga caacgtccgc ctatgcacaa accgaagtac
     8341 tgacaggggt tacccgagga aaagactatg gagtggttta cagtcttccc aaaacccaaa
     8401 tagaacttga aataaaagcc aacaaagtca actatactcc gggagaattc agcaaatatg
     8461 ctgatcgtta cctgcgactg accaacgtct ccgccgaccc tgaagagtac tgggaactga
     8521 ctagcgtaaa agtgaaatcc gtaggtgtgc ccaacagcga aacgacgtat ttcgtaaaat
     8581 tgaaggataa gacagtagca ccgctcatgg aactgacaga ggatggcatt gtgaaaacga
     8641 tcaatgttcc ttacagcaac agcagtgtag gcaaaaaagc cgctcccgct cccacagtcc
     8701 tccaaaagaa agcaaatcct cgtgaattcc tgaccgaaga gattctgatg gctagctcta
     8761 ccgccaagat ggccgaactg gtggctaaag aaatctataa catccgcgaa agcaaaaatg
     8821 ccttattgcg cggacaggct gacaatatgc cttcagacgg agcacagctt aagattatgc
     8881 tcgacaatct gaatgcacag gaagaagcca tgacgcaaat gttctccggc acctgcaaca
     8941 aggaagagag aacattcact gtccgcctta cccctgacaa ggaatttaac aatgaagttg
     9001 ctttccgctt ctcgaagaag ttaggtgtag ttgccaacaa tgatttggca ggaactccgt
     9061 tttatatcag tctgaaagac ctgaaatcgg tcaagatacc acaggaagat ggtaagaaga
     9121 agaaagattt ggatggaatc gcctacaacg tacccggaca agctatggtt acattgaccg
     9181 acggcaaaaa gaaactttac gaaggtgaac ttcctattac tcaatttggt gtgatagaat
     9241 atctggctcc ggttttgttc aacaagaatt ctaccatcaa agtttatttt gatccgaata
     9301 cgggaggatt gctcaaagtg gacagagaag aagggaaata gaaaaacgag aaagtgaact
     9361 tctaaaaaac aaagaatatg gttggtgaag gacatgcatt cgacatgata cgccgaataa
     9421 aagagggacg ggaagcttcc cgcctacgtc gtgaacgtgc taacgacaag ttgaagcatt
     9481 taaaccgtgc aaacgaacct tatccactac ccaataccac tcccgaagaa atggaacgta
     9541 tcatccacga ctcggagaaa aagaaagaga aagacagcaa ttattttgtt tggggaacgc
     9601 ttattatcat gggagtcctg atagcaattg ccgtcatact ttgggctgta tttatcaaat
     9661 aaataataat aaattcacca cagaggacac ggaggacacg gaggacacag aggtttaatc
     9721 ttttttattc actatagagt aacacagagt ctcacgtatt gagaatcgta tttatcgctc
     9781 tgttttactt gcggaaagag agagagaaga actctgtgtc ctccgtgtcc tctgtggtga
     9841 aatataaatt cctatttatg cgactggtat caccagtttt ataaatccat ctttctgcat
     9901 ttgagaaaga taagccgata cacgcgactc gtagccctct tcattttgaa aatggtctgc
     9961 gagtttttct ataatctcac gaacattgcg ttttccatct atcagttccc atacagccgt
    10021 accgtgttct tccaatcgca catgaagttc tttcgacatt cctgccggta caaggaagcg
    10081 ttgcatccac ggatatttaa aacggggaaa ggagagcaca atcgtctccc cttccctttc
    10141 tgctgtaata tgttcactgc gacagggaat gacctctaac aggttgattt tctctttggc
    10201 agccatactt cttatttttt atttcagagt attcatactg ataccctttt gtttacacct
    10261 tgatacaaaa ttcctttgtt actttaggta ttgaatttcc cagttacttt tggatattcg
    10321 cctcttccag accgtatccc ttcttcttgt tctctgcctt caacatcaaa gccacaatca
    10381 gagcaagtac accaaagaga gcaaaaatag tcatcggcaa tgtgtaatca taagtctgtg
    10441 caccgtctac caccggacct ttgcaataag tattcaatac ccatccgatt aacaaaggaa
    10501 cacccatcag tccccagttc tgtacccaga aaatcaaagc gtaagcagta cccagctgtt
    10561 tttccggaat aatcttcgga acagaaggcc acatagccga aggcaccaat gagaaagcaa
    10621 atcccaatat aatcattata atagtagcaa accaccatat attcagtata ggcagggcaa
    10681 acatggtatg tacaaaaatt agcatcaatg atccgatcac catcaatgtg gctcctttac
    10741 cgatacggtc atataacgaa ccgaacaacg gagtcaggat aattgcacca atcggcaaca
    10801 atccgggaat cgttcccgcc agtttcggat ctacattata tttctgcacc atcaagtcgg
    10861 cagcatattt gataaaaggg aagacggccg agtagaacaa tacgcacagc aatgcgatca
    10921 accagaatcc cttattggta atgatataca caatatcttt catacggaac ggttcttccg
    10981 gttccaaacc ttctgcatcc aaagaagcat ccaatttctt atcgtagaaa gtataaagga
    11041 agaaagcaat agtacctaca cacagcataa tcagacaaaa cagaatagga gcaggaatat
    11101 tggtatggaa tgcaccaccc tcgtccgtat atccgaagaa gtctgccaaa ggaactgtca
    11161 acaccatcgc cagagttgtc ccaatacgtg ccgtagccat ttcaagtccc atagccaatg
    11221 ccatttcctt gcccttgaac catttcacta taatcttgga aacagtgata ccagcaatct
    11281 ccacacctac accaaagata gcatatccca atgcagccaa cgtcacctgt gttttgaatc
    11341 cgaagagcat ggcaccttcc ggaaaagtag tagaaatcgc atagtatttc aatccacaac
    11401 caaacaccat caataagcaa gctcccattc cggtgaaacg aactcccatt ttgtccaaaa
    11461 tgataccacc gaagatcagc atcaacaaga atacgttaaa ccaaccgtaa gcgcttgtga
    11521 agaatccata atcaagacta tcccataata gttctttctc aagcatgggt tttagaggag
    11581 acattacgtc ggtgaggaaa tagccgcata gcatagtaaa tgcgaccaat gctagaacac
    11641 tccatcggag tacggcggag tcattcaatt tctgtttcaa atgttctgtc attgttatat
    11701 ttaaaaaagt agttaataat cttatacagc caacaaaggt agttaaatct cgtttgtttc
    11761 tatcacaaag agattgtttt tacaagaaaa agttaagtgc ggattacact gaccacgcgg
    11821 aacattgaaa atccgtgtaa tctgcgtaat ccgcacttaa atatcaaaga aatgcagcat
    11881 ccgtctgcac cttcccatta atggttttac cccaaagtct tacctgacga cggagtgaat
    11941 tactctgctg caggagcagg agtttcagta gccggtgccg gagtttctgt agcaggtgca
    12001 ttggtagcag gagcttcagt ttgcggcgca gccgtacctg cgggtaagtt atacgggtta
    12061 gtctgttgtt ctttctgtgc ctgttccaac actgcgtctt tagcaacagc agaacgagga
    12121 actacataag cagtagcaat gctcattaca accataaaga tggccaggcc ccatgttgct
    12181 ttttccagaa agtctgtagt cttgcgcacg cccatgatgg cgttagatga agagaaacca
    12241 gaagcaagtc cgcctccttt tgagttctga atcagcacga tgaaacacat caacaaggct
    12301 gcaataacca ttaagata
//
