LOCUS       c01237_gnlPro..         5575 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CACIEOLF_1237.
ACCESSION   c01237_gnlPro..
VERSION     c01237_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 08:31:15
            Original ID  :: gnl|Prokka|CACIEOLF_1237
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5575
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..84)
                     /locus_tag="ctg1237_1"
                     /transl_table=11
                     /translation="METVENKYITVAYKLYTVEDGEKELFEE"
     protocluster    1..5575
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[562:4796]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      563..4796
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..5575
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..5575
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             563..2362
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1237_2"
                     /sec_met_domain="ILVD_EDD (E-value: 3.1e-217, bitscore:
                     710.6, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKQLRSSFSTQGRRMAGARALWAANGMKKNQMGKPIIAIVNSFT
                     QFVPGHVHLHEIGQLVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPAVFVSGGPMEAGEWNGQHLDLID
                     AMIKSADESVSDQEVANIEQNACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     ENRTQLFKDAAELIVKNAKLYYEEGDESVLPRSIATRQAFLNAMTLDIAMGGSTNTVLH
                     LLAVAHEAEVDFKMDDIDMLSRKAPCLCKVAPNTQKYHIQDVNRAGGIIAIMDELAKGG
                     LIDTSVRRVDGMSLAEAINEYSITSPNVSEKAIKKYSSAAGNKFNLVLGSQGMYYKELD
                     KDRANGCIRDLEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQEA
                     ACEGILGGRVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHISPEAAAGGNIGKIVDGDIIEIDIPARKINVRLTDEELAARPMTPVTRDRY
                     VPKSLKAYASMVSSADKGAVRII"
     CDS             2487..4181
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1237_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.6e-48, bitscore:
                     152.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDLITGAEALMRSLEHQGVTTIFGYPGGSIMPVFDALYDHQNIL
                     NHILVRHEQGAAHAAQGYARVSGDVGVCLVTSGPGATNTVTGIADAMIDSTPIVVIAGQ
                     VGTGFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAVARAFYIARSGRPGPVVLDF
                     AKNAQVEKTKYEPTKVDFIRSYVPVPDTDEESVQAAAELINNAERPLVLVGQGVELGNA
                     QSELREFIEKADMPAGCTLLGLSALPTEHPLNKGMLGMHGNLGPNINTNKCDVLIAVGM
                     RFDDRVTGNLATYAKQAKVIHFDIDPAEVNKNVKVDVAVLGDCKETLASVTKLLKKNTH
                     TEWIDSFKEYEKVEEEKVIRPELHPATNSLSMGEVVRAVSDATHHEAVLVTDVGQNQMI
                     SARYFKYTKERSIITSGGLGTMGFGLPAAIGATFGAPERTVCVFMGDGGLQMNIQELGT
                     IMEQKAPVKIICLNNNYLGNVRQWQAMFFNRRYSFTPMLNPDYMKVASAYDIPSKRVFT
                     REELKEAIAEMLATDGPFLLEACVVEEGNVLPMTPPGGSVNQMLLEC"
     CDS             4239..4796
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1237_4"
                     /sec_met_domain="ALS_ss_C (E-value: 9.9e-20, bitscore:
                     59.1, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDKTLYTIIVHSENIAGLLNQVTAVFTRRQINIESLNVSASSIK
                     GVHKYTITAWTDKDIIEKVVKQIEKKIDVIQAHYFTEDEIYFHEIALYKVSTPAFQENP
                     EASKLIRRYNARIVEVNPVFSIVEKNGMSEDITSLYGELKALNCVLQFVRSGRVAITTS
                     CFERVNEFLDGREAMYNQSKNQ"
     CDS             4802..5545
                     /locus_tag="ctg1237_5"
                     /transl_table=11
                     /translation="MSEENRIGTYQFVAEPFHVDFNGRLTMGVLGNHLLNCAGFHANDR
                     GFGIATLNEDNYTWVLSRLAIELDEMPYQYENFSVQTWVENVYRLFTDRNFAILDKDGK
                     KIGYARSVWAMINLNTRKPADLLTLHGGSIVDYVCDEPCPIEKPSRIKVTSDQPIATLT
                     AKYSDIDINGHVNSIRYIEHILDLFPIELYKTKRIRRFEMAYVAESYFGDELSFFCDEV
                     NANEFHVEVKKNGNEVVCRSKVIFE"
ORIGIN
        1 ttcttcgaac aattcttttt caccatcttc cactgtatat agcttatatg caacggtgat
       61 gtacttgttt tctactgttt ccatctgata tttatagttt ctaattaata aatcccttat
      121 ttagggtgga caaagatacg aataatttgc ttgctaccgg gggcatacgg agtaaatttc
      181 agattattaa gcgcttttgt cagaaatgga cagtcattct ctactaactg atagttgcaa
      241 attcaacctt taagtgataa aatttaggtt tattaccgtt cttttcttac gattattcgc
      301 tttttagtga tttttttctt cgatttgttt ggagataata aaaaagccct tacctttgca
      361 gcacgaaaat aaagaaaaga agatatgaat atgttacata catctattaa cctagcagtc
      421 ctgcatatta ttcgcgtcgt ggtggtccca tcaagagcgt gagaaaggtt tttgtgttgt
      481 atgtgttcgt accataaaag atagaattta gagcctttct cacttgtgtg aggaaggctc
      541 tttaattaaa agatagattg aaatgaaaaa gcaattacgc agttcgttta gtacacaagg
      601 ccgtcggatg gcgggagccc gtgcattgtg ggcagccaac ggcatgaaga agaaccagat
      661 gggtaaaccc attatcgcta tcgtcaattc gttcacacag tttgtcccgg ggcatgtaca
      721 cctacatgaa atcggtcagc tggtgaaggc agagattgag aagctaggat gcttcgctgc
      781 ggaattcaat acaatagcta tcgacgacgg tatagcaatg ggacatgacg gtatgcttta
      841 ttcgcttcct tcacgtgata tcattgcaga cagcgtagaa tatatggtca atgcgcacaa
      901 ggcggatgca atggtatgta tcagcaattg cgataagatc actcccggaa tgttgatggc
      961 ggctatgcgt ctgaatatcc ctgctgtatt tgtatcgggt ggtccgatgg aagcgggaga
     1021 atggaatggc cagcatctgg atttgatcga tgcgatgatt aaatcggccg acgagagtgt
     1081 cagcgatcag gaagtagcga atatcgagca aaatgcttgt cctacttgcg gatgctgctc
     1141 cggtatgttt accgccaact cgatgaactg cctgaatgaa gcaatcggac tggctcttcc
     1201 cggcaacgga accattgtag cgacacacga aaaccgtacg caacttttca aagacgctgc
     1261 ggaactgatc gtgaaaaatg caaaattata ttatgaagaa ggagacgaaa gtgtacttcc
     1321 ccgtagcatc gctacccgtc aggctttcct gaacgccatg acgctggata tagcaatggg
     1381 gggatctacc aatacggttc ttcacttatt agctgttgct cacgaagcag aggtagactt
     1441 caagatggat gatatcgaca tgctttcccg caaggctcct tgtctctgca aggtggctcc
     1501 caatacacag aaatatcata ttcaggatgt aaaccgtgcc ggtggtatta ttgctatcat
     1561 ggatgaactg gcaaaaggcg gtctgataga tacatctgtt cgacgggtag acggaatgtc
     1621 actggcagaa gccattaacg aatattcaat caccagcccg aatgtgagcg aaaaagcaat
     1681 taagaaatat tcgagcgcag ccggaaataa atttaatctc gtacttggtt cacaaggtat
     1741 gtactataag gaactggata aggaccgtgc aaacggatgt atccgtgact tggaacatgc
     1801 ttacagtaaa gacggcggac tggccgtatt gaaaggcaat attgctcaag atggttgtgt
     1861 agtaaaaaca gcaggtgtag acgaaagtat ctggaagttt accggacctg ccaaagtatt
     1921 tgattcgcaa gaagcagcct gtgaaggcat cctcggaggt cgagtcgtca gtggcgacgt
     1981 cgtcgtcatc acgcacgaag gtccgaaggg tggtcccggt atgcaggaaa tgctttatcc
     2041 tacctcttat atcaaatctc gtcatctcgg aaaagaatgt gctttgatta ccgacggacg
     2101 tttcagcggt ggaacttccg gattgagtat cggacatatt tctcctgaag cggcagctgg
     2161 aggcaatatc ggaaaaattg tagacggaga cattatcgaa atcgatattc cggcccggaa
     2221 gattaacgtg cgactgacgg atgaagaact ggcggcccgt ccgatgactc ctgtcactcg
     2281 tgaccgttat gtaccgaaga gcctgaaggc gtatgccagc atggtaagct ctgccgataa
     2341 gggagcagtg agaattatat aatatagttg gtgatagttg ataggtaata gttagctgcg
     2401 cagcacttag cgcaatgatt gtaaaccatt cattttcaac tgtcatttct caactatcat
     2461 ttatcattta tcaactatca actaatatga aagatttaat aacaggtgca gaggctttga
     2521 tgcgctcctt ggaacatcag ggagtgacta ccatctttgg ttaccccggt ggttctatta
     2581 tgccggtatt cgatgccttg tacgatcatc aaaatatatt gaaccatatc ttggttcgtc
     2641 acgagcaggg agccgcccat gccgcacaag gttatgcccg tgtatcgggt gatgtaggtg
     2701 tttgcctggt gacgagcggt cccggagcaa ccaatacggt aacaggcatt gcagatgcga
     2761 tgatcgatag tacgcctatc gtggtgattg ccggacaggt aggaacaggc tttcttggga
     2821 cggatgcttt tcaggaagtt gacttggtag gtatcaccca gccaatcact aaatggagtt
     2881 atcagattcg ccgtgcggaa gatgtagcct gggcggtagc acgtgcgttt tacattgctc
     2941 gtagtggtcg tccggggccg gtggtactgg actttgctaa aaatgcgcaa gtagagaaaa
     3001 cgaaatacga accgacgaaa gtcgatttta tccgtagtta tgttcctgtt cccgatacgg
     3061 atgaggagtc tgtacaggct gctgccgaac tgattaataa cgctgaacgt ccgcttgtat
     3121 tggttggaca aggtgttgaa ctgggaaatg cacagagcga attgcgcgag tttatcgaaa
     3181 aagcggatat gcctgcgggt tgtacgctgc tcgggctttc ggctttgccg acagaacatc
     3241 cgttgaataa aggtatgttg ggtatgcacg gcaatctggg accgaatatc aataccaata
     3301 aatgcgatgt gctgattgct gtcggtatgc gttttgacga ccgtgtgacc ggtaatttgg
     3361 ctacttacgc caaacaggca aaagtgattc attttgatat cgatcctgcg gaagttaata
     3421 agaatgtaaa ggtagatgta gctgtattgg gagattgcaa ggaaacactg gcttctgtga
     3481 cgaaacttct gaaaaagaac actcataccg aatggattga tagcttcaaa gaatatgaga
     3541 aagtagagga ggaaaaagta atccgtcctg aacttcatcc tgccacaaac tctttgagta
     3601 tgggggaagt ggtacgtgcg gttagtgatg ctactcacca tgaagctgtt ttggtaacag
     3661 atgtaggtca aaatcagatg atatctgcac gttactttaa atatacgaaa gaacgcagta
     3721 tcattacttc cggaggactt ggaacaatgg gcttcgggct tcccgcagct atcggggcaa
     3781 ctttcggagc accggaacgt accgtatgcg tatttatggg agatggcgga ctgcaaatga
     3841 atattcagga actgggtacg attatggagc agaaggctcc ggtgaagatt atctgcctga
     3901 acaataatta cctcggaaac gtacgtcagt ggcaagctat gtttttcaac cgtcgctatt
     3961 cgtttacccc gatgttgaat ccggattata tgaaagtggc ttcggcttat gatattcctt
     4021 ccaagcgtgt tttcactcgt gaagaactga aggaagctat tgctgaaatg ctggcaacgg
     4081 acggtccgtt cctgctcgaa gcttgcgtgg tggaagaagg taatgttttg ccgatgactc
     4141 ctccgggtgg ttcggtaaac cagatgttgc tggagtgcta ggagaagttg agagttgaga
     4201 atggagagtt gagagttcgc atttaaaaaa ttagagttat gagtgataaa acgttatata
     4261 caatcattgt tcattcggag aatatagccg ggttgctgaa tcaggtaact gctgtattta
     4321 cccgtcggca aataaatatt gagagtctga atgtatctgc ttcttctatt aaaggtgtac
     4381 ataagtatac aataacagct tggactgata aggacatcat tgagaaggta gtgaaacaga
     4441 tcgaaaagaa gatcgacgtg attcaggcac attatttcac agaggatgag atttatttcc
     4501 acgagattgc attatataag gtgtctactc ctgcttttca ggagaatccg gaagcatcca
     4561 agctgattcg tagatacaat gcacgtatag tggaagtcaa tccggtattt tctattgtcg
     4621 agaaaaatgg aatgagcgaa gatataactt cgctctatgg tgaactgaag gctttgaatt
     4681 gtgttttgca gtttgttcgt tcgggacgtg tagcgattac taccagctgt tttgaacggg
     4741 tgaatgagtt tctcgatgga cgggaagcta tgtataacca aagtaaaaac caataagaat
     4801 aatgagtgaa gaaaatagaa tagggactta tcagtttgtg gcagaaccgt tccatgttga
     4861 cttcaacgga cgtctgacta tgggggtact gggaaatcat ctgctgaatt gtgcaggttt
     4921 tcacgccaat gaccgtggtt ttggtattgc aacgctgaat gaggacaatt atacatgggt
     4981 gctttcacgt ctggctattg agttggatga aatgccttat cagtatgaga atttctcggt
     5041 tcagacgtgg gtggaaaatg tctaccgttt gtttacggac cgtaattttg ctatcctcga
     5101 taaggatgga aagaagattg gctacgcacg ttccgtatgg gcaatgatta atcttaatac
     5161 ccgcaagcct gccgacttgt tgactttgca tgggggaagt atcgtagact atgtctgtga
     5221 tgagccttgc ccgattgaaa agccttcacg catcaaagtg acaagcgatc agccgatagc
     5281 taccctgacg gcaaagtaca gtgatataga tatcaatggt catgtaaaca gcatccgtta
     5341 catcgaacat atccttgatt tgttcccgat tgaattgtat aagaccaaac gtatccgtcg
     5401 ttttgaaatg gcgtatgtgg cggaaagcta ttttggtgat gaactctctt tcttctgcga
     5461 tgaagtgaat gcaaacgagt ttcacgtaga agtgaagaag aatggcaacg aagttgtttg
     5521 ccgctcgaaa gtgatatttg aataaatgtg agaatataaa atcaattaat aacag
//
