LOCUS       gnlProkkaGPCMMPKA_406  10466 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GPCMMPKA_406.
ACCESSION   gnlProkkaGPCMMPKA_406
VERSION     gnlProkkaGPCMMPKA_406
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 09:52:53
            Original ID  :: gnl|Prokka|GPCMMPKA_406
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10466
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10466
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[7759:8113]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      7760..8113
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..10466
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10466
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             32..1066
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg406_1"
                     /sec_met_domain="PF04055 (E-value: 8.3e-19, bitscore: 58.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKYPLLGMTLTELQSVTKDLGMPAFAAKQIASWLYDKKVTSIDE
                     MTNLSLKHRELLKGEYDLGISAPVDEMRSVDGTVKYLYQVSDNHFVEAVYIPDEDRATL
                     CVSSQVGCKMNCKFCMTGKQGFTASLTANQILNQIAALPERDKLTNVVMMGMGEPLDNL
                     DEVLKALHILTASYGYGWSPKRITLSSVGLRKGLQRFIEESECHLAISLHSPFPSQRSE
                     LMPAERAFSIKEMVDLLKNYDFSKQRRLSFEYIVFKGVNDSLIYAKELLKLLRGLDCRV
                     NLIRFHAIPGVDLEGAGMEAMTSFRDYLTSHGLFTTIRASRGEDIFAACGMLSTAKQEE
                     SNKN"
     CDS             1141..2187
                     /locus_tag="ctg406_2"
                     /transl_table=11
                     /translation="MKKYLFYLSMALVAVVLFSCKSGKKSVFTPTSSGRAYEVLVVVEK
                     PVWERPAGRALYNVLDTDVPGLPQSERSFRIMSTSPKDFDAILKLVRNIIIVDIQDIYT
                     QPKFKYAKDVYASPQMILTIQAPDEASFEKFVEENKQPIIDFFTRAEMNRQISFLEKNH
                     NDYISTKVGSMFNSDIWLPAELSSSKTGEDFFWAGTNAATGDQNFVIYSYPYTDKDTFT
                     KEFFIHKRDSVMKANIPGAKEGMYMATDSSTVEVRPIDIHGDYTMEARGLWRIKGDFMG
                     GPFVSHTRLDKASHRIITTEVFIYSPDKMKRDLMRRLEASLYTLQLPTEKAQEQIPMGI
                     EQEEKTNK"
     CDS             2192..3289
                     /locus_tag="ctg406_3"
                     /transl_table=11
                     /translation="MEDNKIKIGITQGDINGVGYEVILKTFADPVMLELCTPVIYGSPK
                     VAAYHRKSLDLPTNFSIVNTAAEAAHNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     KAIEEFREGLIDVIVTAPINKHTIQSEGFAFPGHTEYIEQRLGNGSKSLMILMKEDFRV
                     ALVTGHIPVREIASSITKELIQEKLAIFNRSLKQDFGIGAPRIAVLALNPHAGDDGLLG
                     TEEQEIISPAIQEMAAKGILCYGPYPADGFMGSGNFTHFDGVLAMYHDQGLAPFKALAM
                     DEGVNYTAGLPVIRTSPAHGTAYDIAGKGVACEDSFRQAIYVAIDVFRNRQREKEAHAN
                     PLRKQYYEKRDDSDKLKLDTVDDDI"
     CDS             3314..4540
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 389.6; E-value:
                     3.4e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg406_4"
                     /transl_table=11
                     /translation="MTKAEIQQVKLRFGIIGNTEALTRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPLPTQARLLRVLESGEFIKVGSSKVQKTDVRIVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGEDVLLLFRKFASDFAEKYRMPAIQLTEDAKRV
                     LLSYSWPGNVRQLKNITEQISIIETNREINAPILQSYLPAQSTQRLPALFGVKTGKSFE
                     SEREILYQVLFDMRQDVTELKKLVHEIMSERGAVTSNVGTFYTPAPVVAPTPSVPAIIH
                     PVKPNCPDDDDIQDTEEYVEESLSLDEVEKEMIRKALEKHHGKRKSAAKDLNISERTLY
                     RKIKEYGLE"
     CDS             4548..5048
                     /locus_tag="ctg406_5"
                     /transl_table=11
                     /translation="MRISLLVFTLVVGISCTVSYKFNGGNINYDKVKTISIADFPIKSD
                     YVYAPLGTKFNEDLKDIFLRQTRLKLVNNNADLEIDGEITGYNQYNQAVSADGYSSETK
                     LTITVNVRFVNNTNHEQDFEQQFSAFRVYDSRELLTAVQDGLIAEMTKEITDQIFNATV
                     ANW"
     CDS             5054..5809
                     /locus_tag="ctg406_6"
                     /transl_table=11
                     /translation="MISANLQQWIQHPETLNKDTLYELRTLVTRYPYFQSLRLLYLKNL
                     YLLHDISFGAELRKAILHVADRRKLFYLIEGERYILKPRKKNALPETEVLEEEPSLDRT
                     LSLIDAFLATVPEEVSAQTSLDYATDYTTYLLQEDDTPELEETPKLRGHELIDGFIERS
                     EEETSIRLQPADENKAISEEEESETHHEEDEDDSCFTETLAKIYVKQHRYSKALEIIKK
                     LSLKYPKKNAYFADQIRFLEKLIINAKSK"
     CDS             5814..6194
                     /locus_tag="ctg406_7"
                     /transl_table=11
                     /translation="MYLLLVILMVIAAILMCFIVLIQNSKGGGLASGFSSSNQIMGVRK
                     TTDFLEKATWGLAAFMVVMSIATAYVVPTSSSKTQDVIMEQAQQEEQTNPYNLPVGTTA
                     PKTDAAAPVEAPATETPATPAN"
     CDS             6365..7753
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 97.1; E-value: 1.4e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg406_8"
                     /transl_table=11
                     /translation="MTEQLKNKLSDSKTLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACILMVLGCGLKYY
                     AISTTFPEGALIMGFKTQVFLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPIADYFGYTDESGSFHTNIPMPILLCLIMLCIGTIAFFIYTF
                     YDKKLDASLDAQGEEPEEPFRMKDVMLIVTNKGFWLIALLCVLFYSAVFPFIKYATDLM
                     VQKYNVDPKLAGNIPGLLPIGTIFLTPLFGTLYDRIGKGATLMIIGAVMLIGVHTLFAL
                     PILNVWWFATVIMIVLGIAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMAIFACFGVLALIVALMLKAEDKKKGYGLQEA
                     NIKK"
     CDS             7760..8113
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg406_9"
                     /sec_met_domain="PF05402 (E-value: 1.6e-17, bitscore: 53.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 2.3e-10, bitscore:
                     29.8, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADVKEKINLLDVIPFRSENITAEKGSDGTVTIAFPRFKYEWMRR
                     FLLPKGMSADIHVRLEDHGTAVWELIDGKRTVRRIIEELAEHFNYEENYESRITAYITQ
                     LQKDGFVKLVIEN"
     CDS             complement(8247..9302)
                     /locus_tag="ctg406_10"
                     /transl_table=11
                     /translation="MKKLIILTGLLLSTSAYAQTEVTAGVTRGKDYGVTYALPKTAINI
                     EVKVNKVTYTPGEFSKYADRYLRLTDVSGEPQEYWELVSVKAKSVGIPDSEHTYFVKLK
                     DKTVAPLIELTEDGIVKSINVPLSPKKSAPMQPATTQKKKINPRDFLTEEILMAGSTAK
                     MAELVAKEIYNIRESKNALVRGQADNMPKDGEQLKIMLANLEEQEAAMTEMFSGTLNKD
                     EKIFNIRLTPDKEMDNEVAFRFSKKLGIVANNDLAGEPVYITLKNLKTVNVPEDDGKKK
                     VDGIAYNVPGKAQVTLTEGKKQWFNGELPVTQFGTIEYLAPALFNKKSTVQVTFNPDTG
                     GLIKVDREEGE"
     CDS             complement(9375..10466)
                     /locus_tag="ctg406_11"
                     /transl_table=11
                     /translation="MAAVVKYINASPATVVAIDIPSGLMGEENTFNVKANIIRAQLTLS
                     LQLPKLAFLFAENSEFVGEWKLLDINLSREAIEETESNYALLEAEEIHALIKPRNTFSH
                     KGNFGHALLIAGSYGMAGASILAARACMRSGVGLLTVHAPIRNNDILQISVPEAIIESD
                     ASDTYFACPTDTDDYQAVGIGPGIGRSEETEAALLEQLSGCQTPLVLDADALNILANHR
                     HALTTLPKGSILTPHPKELERMVGKCQNSYERLMKACELARTAKVHIILKGAYSAIITP
                     SGKCYFNSTGNPGMATAGSGDVLTGVVLALLAQGYPAEEAAKIGTYVHGLAGDFARKKQ
                     GVISMTAGDIISNLPLAWRLVSE"
ORIGIN
        1 ttgcatgaat aaataaatat ttgtagtaaa tatgcccaaa tatccgcttt taggaatgac
       61 ccttaccgaa ttgcaatctg tcaccaaaga tttggggatg cctgcttttg cagccaaaca
      121 gatcgcttcc tggttatacg ataaaaaagt gacttctatt gatgaaatga ccaatctgtc
      181 gttgaagcat agagagttgc tcaagggaga gtatgatttg gggatatccg cgcctgttga
      241 tgagatgcgt tccgtagatg gtacggtgaa gtatctttat caggtgagtg acaatcattt
      301 tgttgaagcg gtgtatattc cggacgagga tcgggcgaca ttgtgcgtgt cttctcaggt
      361 aggctgtaaa atgaactgta agttctgcat gacgggtaaa caaggattta ccgcaagtct
      421 gacagccaat cagatcttga atcaaatcgc agcattgcca gagcgggata agttgactaa
      481 tgtcgtgatg atggggatgg gcgagcctct cgataatttg gatgaagtat taaaagcact
      541 gcatatcctg accgcttcgt atggatacgg atggagcccc aagcgtatta ctttgtcgtc
      601 tgtaggattg cggaaaggac ttcaacgctt tattgaagaa agcgaatgtc atctggctat
      661 cagcctgcat tctccttttc cttcacaacg ttctgagctg atgccggccg aaagggcttt
      721 ctcgattaaa gaaatggtcg atctgttaaa aaactatgat tttagtaaac agcgcagact
      781 ttcgtttgaa tacattgttt ttaagggcgt caatgattcg ctgatttatg ctaaggagct
      841 gttgaaattg ctgcgtgggc ttgactgccg ggtgaactta atccggtttc atgccattcc
      901 tggggtagac ctcgagggtg ccggtatgga ggctatgacg tcatttcgtg actacctgac
      961 ctcacatgga ctgttcacta ccattcgagc ttcccgggga gaagatattt ttgccgcttg
     1021 cgggatgtta tcgacggcta aacaggagga gagtaacaag aattaatata aattatcagc
     1081 acattggatg aaagtatacg accatttcgt agatttgtga aaacattaaa attgatgcat
     1141 atgaaaaagt acctgtttta cctcagtatg gctcttgtag cagtagtgtt gttttcttgt
     1201 aaaagcggca agaagagtgt gtttactcca acttccagcg gacgtgctta tgaagtcctc
     1261 gttgtggttg agaagcctgt gtgggagcgt cctgccggta gagctttgta caatgtgctt
     1321 gatacagatg tgcccggact tccgcaatcg gaacgttcgt tcaggatcat gtctacttct
     1381 cccaaagatt ttgatgccat cctgaagttg gtgcgcaaca ttattatcgt agatatacag
     1441 gacatttata cccaacctaa attcaagtat gccaaggatg tatatgcatc tcctcagatg
     1501 attttgacta tccaggctcc ggacgaggca tcgtttgaga agtttgtcga agagaacaaa
     1561 cagccgatta tagacttctt tacccgtgcc gaaatgaacc gtcagatctc tttcctggag
     1621 aaaaatcata atgactatat ttcgacgaaa gtaggtagta tgttcaacag tgatatctgg
     1681 cttccggccg aactgagcag ttcgaagaca ggagaagact ttttctgggc aggtactaat
     1741 gccgctaccg gagaccagaa ctttgtaatc tactcttacc cgtatacaga taaggatacc
     1801 tttacgaaag agttctttat ccataagcgc gattcagtga tgaaggctaa tattccgggt
     1861 gccaaagagg gtatgtacat ggcgactgat tcgtctaccg tagaggttcg tccgattgat
     1921 attcatggag attacacaat ggaagcacgc ggactgtggc gcataaaggg cgatttcatg
     1981 ggtggcccgt ttgtttcgca cacccgtctg gataaagcca gccaccgtat tatcactaca
     2041 gaagtattta tttactcacc cgataaaatg aaacgtgacc tgatgcgccg attggaagca
     2101 tctctgtata ctttgcaact tcctaccgag aaggcgcagg aacagattcc gatgggcata
     2161 gagcaggagg agaaaactaa caaataacaa aatggaagat aacaaaataa aaattggcat
     2221 cactcaggga gacataaacg gggtaggata cgaagtcatt ttaaaaacgt ttgccgaccc
     2281 cgtcatgttg gaactctgta caccggtcat ttacggctct ccgaaagtgg ctgcatatca
     2341 ccgcaagtcg ctcgatttgc ctactaactt cagtattgtc aataccgctg cagaagctgc
     2401 ccacaatcgc ctgagcgtgg tcaactgtac ggatgacgag gtgaaagtag agttctcaaa
     2461 acccgatccg gaagccggta aagcagcttt gggagcactt gagaaggcga tagaggagtt
     2521 cagagaaggc ttgatcgatg tcatagtgac ggctcctatc aataagcata cgattcagtc
     2581 cgaaggattt gcttttcccg gacatacgga atatatcgaa cagcgtctgg ggaatggttc
     2641 aaaatcactg atgatcctga tgaaagagga tttccgggta gctttggtga caggacatat
     2701 tccggttcgc gagatagcct cttcaataac caaggaactg attcaggaga aacttgccat
     2761 attcaaccgg tcgttgaaac aggatttcgg gattggtgcg ccgcgcatcg cagtgttggc
     2821 actgaatccg catgccggag acgacggatt gctcggtacg gaagaacagg aaatcatttc
     2881 tcctgctatt caggaaatgg ctgccaaggg aatcttgtgc tatggccctt atccggctga
     2941 cggatttatg ggatcgggca atttcaccca ttttgacgga gtactggcca tgtatcacga
     3001 tcagggattg gctcctttca aggcattggc catggatgaa ggtgtgaact acacggcggg
     3061 tttgccggtg atacgcactt ctcccgcgca tggtacagcc tatgatattg caggaaaagg
     3121 cgttgcttgc gaagattcat tccgtcaggc tatttatgta gcgatcgacg tattccgtaa
     3181 ccgtcaacgt gagaaggaag cacatgccaa tccgttacgt aaacagtatt acgagaaacg
     3241 agacgacagt gataaactga agctcgatac agtagatgat gatatttaat caggaaggga
     3301 gtttagtgcg aatatgacaa aagcggaaat acaacaggta aaactaaggt tcggtattat
     3361 tggtaacact gaagctttga cgcgtgcgat agatgttgcc atacaggtgg cacctaccga
     3421 tttgtccgtg ctaataaccg gagagagtgg tgttggtaag gaaagtttcc ctcagatcat
     3481 tcaccaatac agtcgccgaa agcatggaca gtatattgct gtcaactgtg gtgctattcc
     3541 tgaaggaacc atcgattcgg aactgttcgg tcatgaaaaa ggggctttta cgggagccat
     3601 cggtgagcga aagggctatt ttggtgaagc cgacggcgga actatttttc tggatgaagt
     3661 cggagaattg cctttgccca cgcaggcacg tttgcttcgt gtactcgaga gtggggagtt
     3721 tataaaagta ggctcctcca aagtacagaa aacggatgtc cgcattgtgg ctgctaccaa
     3781 tgtcaatttg acccaggcca ttgcagaggg acgtttccgt gaggatttat actatcgtct
     3841 caatacggtg cccatccaga tccctccttt gcgggagcgt ggagaagatg tgctgttact
     3901 gttccgtaag tttgcaagtg actttgcaga gaagtatcgt atgcccgcca tacagctgac
     3961 cgaagatgcc aaacgggttt tgctgtctta ttcctggccg ggtaatgtgc gtcagttgaa
     4021 gaatatcacg gagcaaatct ctataattga gaccaatcgt gagattaatg cccctatctt
     4081 gcaatcttat ctgcctgccc agagtacgca gcgattgcct gccctgttcg gtgtaaagac
     4141 agggaagagc ttcgaaagtg aacgtgaaat cttatatcag gtcctttttg atatgcgaca
     4201 agatgtgacc gaactgaaaa agcttgtaca cgaaatcatg tccgagcgcg gagcggtaac
     4261 ctccaatgtc ggtacgtttt atacgccggc tccggtagta gcccctacac cctcagtgcc
     4321 tgccatcatt catccggtca agcccaattg tcccgatgac gatgacatac aagataccga
     4381 agagtatgtg gaagagtcgc tttcgttgga tgaagtcgag aaagaaatga tacgtaaagc
     4441 ccttgaaaag catcatggca agcgaaaaag cgcggcaaag gatcttaata tatccgagcg
     4501 taccctttac cgaaaaataa aagaatatgg attggaataa aaagataatg cgaatttcac
     4561 tgctggtttt cacactggta gtaggaattt cgtgtactgt ttcttataag tttaatggtg
     4621 gtaatatcaa ttacgataag gtaaagacta tctctattgc cgactttcct attaagtcgg
     4681 actatgttta tgcaccgtta ggcactaagt tcaacgagga cctgaaagac attttccttc
     4741 gtcagacccg tctgaaactg gtgaataaca atgccgacct cgagattgat ggagagatta
     4801 ccggatataa ccagtataac caggctgttt cggccgacgg atactcttct gaaaccaagc
     4861 tgaccatcac agtgaatgtt cgttttgtga acaatacgaa tcatgaacag gacttcgagc
     4921 aacagttctc ggctttccgt gtctatgatt cgagggagtt gctgacagcc gttcaggacg
     4981 gactgattgc ggagatgact aaagagatta cagatcaaat atttaacgca acggtagcaa
     5041 actggtaatt agaatgattt ctgctaactt acaacaatgg attcagcatc cggaaacgct
     5101 gaataaagat actttgtacg agttgcgaac gcttgtcaca cgctatcctt attttcagtc
     5161 actgcgatta ctctatctta aaaatctata tttgttgcac gatatctctt tcggtgccga
     5221 gcttcgtaaa gccatattgc atgtggctga tcgccggaag ctgttttatc tgattgaggg
     5281 tgaacgatat attttgaaac ctcggaaaaa gaacgcactt cccgaaacag aagttttaga
     5341 ggaagagccc agcctcgatc gtacgctttc cctgatcgat gcttttctgg ccaccgtgcc
     5401 cgaagaggtt tcagcccaga caagcctgga ctatgcaacg gactatacca cctatttgct
     5461 gcaagaagac gatacaccgg aactggaaga aactcccaaa cttcgcggtc atgaattgat
     5521 tgacggcttt atcgaaagaa gtgaagaaga aacatccatc cgtttgcaac cggcagatga
     5581 aaataaagct atctccgaag aggaagagag cgagacgcat catgaagaag atgaagatga
     5641 tagctgtttc accgaaacat tggccaaaat atacgtcaaa cagcatcgat attccaaggc
     5701 acttgaaatt attaaaaaat taagtttgaa atatccaaaa aaaaatgctt actttgcaga
     5761 ccaaatcaga tttttagaga aattgattat taacgctaaa tcaaaataac aaaatgtact
     5821 tattattagt tatcttaatg gttattgcag ccatactgat gtgcttcatt gtgttgattc
     5881 agaactcaaa aggcggtggt cttgcttcag ggttctcatc atctaaccag attatgggtg
     5941 tacgcaaaac tacagacttt ctggaaaaag caacttgggg cttagctgca tttatggttg
     6001 tgatgagcat tgctactgcg tatgtcgttc cgacttcttc ttctaaaaca caagatgtca
     6061 ttatggaaca ggcacagcag gaagagcaga ccaaccctta taacctgccc gtaggtacta
     6121 ctgcaccgaa gacagacgct gctgctccgg ttgaagcacc tgccacagaa actccggcta
     6181 ctccggcaaa ctaacaacag attcttttta agaaacgata agcgaagctg caatttcaaa
     6241 ccgaaacttg cagcttcgct tattttttgc cgtaaaatgc atctttttgt taggcataca
     6301 aggcagattt agttaccttt gttcgcaata acacttttac taatttctga gtttaaatat
     6361 tacaatgaca gaacaattga aaaacaaatt gagtgactcc aaaacacttc gttggagtgt
     6421 gctcgctctg gtcgcgttta ctatgctttg cggctatttc ctcaccgatg taatgtcccc
     6481 tttaaagcct atgctcgaga aagagcttct ctgggatagt ttggactacg gattctttac
     6541 cagtgcttac ggatggttca atgtattcct gctcatgttg attttcggtg gtattattct
     6601 cgataagatg ggagttcgtt tcaccggtat gggagcttgt atactgatgg tgttgggttg
     6661 tggactaaaa tattatgcta tctctactac tttccctgaa ggtgctttga ttatgggttt
     6721 caagactcag gtctttctgg cggctttagg atacgctatc tttggtgtcg gcgtagagat
     6781 tgccggtatc actgtctcta agattatcgt gaaatggttt aaaggcaaag agatggcttt
     6841 ggctatggga ctcgagatgg ctaccgcacg tatcggtacc actttggcta tggtgcttac
     6901 cgttcccatt gccgattatt tcggctatac ggatgaaagc ggcagtttcc ataccaatat
     6961 tccgatgcct attttgttgt gtctgatcat gctgtgcatc ggtactatcg cctttttcat
     7021 ttataccttt tatgataaga aacttgacgc ttctttagat gctcagggag aagaaccgga
     7081 agaaccgttc cgtatgaagg acgttatgct gattgtcacc aataaaggct tctggctgat
     7141 tgctttattg tgtgtactat tctattctgc tgttttcccc tttattaaat atgcaaccga
     7201 cctgatggtg cagaagtata acgtagaccc taaactggcc ggaaatattc cgggattact
     7261 accgataggt accatcttcc tgactccgtt gtttggtact ctttatgacc gtatcggtaa
     7321 gggagcgacg ttgatgatta tcggtgccgt catgctgatt ggtgtgcata ctttgtttgc
     7381 gcttcccatt ctgaacgtat ggtggtttgc cactgtgatt atgattgttc tgggtattgc
     7441 tttttcactg gtgccttcgg ccatgtggcc ttctgttccg aaaattattc cggagaaaca
     7501 actgggtact gcctatgctt tgattttctg ggtgcagaac tggggattga tgggggtacc
     7561 tctgttgatc ggatgggtgt tgaataccta ttgcaaaggt cctgttgtgg atggagcgca
     7621 gacttatgac tatactttgc ctatggctat ctttgcttgt ttcggtgttt tggctctgat
     7681 tgtagcttta atgctgaaag cggaagacaa gaagaaggga tacggactgc aggaagcaaa
     7741 tatcaaaaaa taacagtata tggcagacgt gaaagagaaa ataaatcttt tggatgtaat
     7801 tcctttccgt agtgaaaata ttacggccga aaagggaagc gatggtaccg ttaccattgc
     7861 tttcccccgg tttaaatacg agtggatgcg gcgattcttg ttgcctaaag gaatgtctgc
     7921 ggatattcat gtccggctgg aagatcatgg cactgccgta tgggagttga ttgacggaaa
     7981 gagaaccgta cgccggatta ttgaagagct ggcagaacac ttcaattatg aagaaaatta
     8041 cgaatcacgt attacggctt atatcactca gttgcagaaa gacggatttg tgaaattagt
     8101 gattgagaac tgattgcatt acgatatact atcggaatat aataaagaga ctccggctga
     8161 tttaaaaatg aagtgcaccc taaaagttaa acatgaactt ttggggtgca cttcatttaa
     8221 gatcggccgg agtttttgat tatgctttat tctccttctt ctctatctac cttgatcaag
     8281 cctcctgtat ccgggttgaa agtaacctga acagtcgatt tcttattgaa aagcgccgga
     8341 gccagatatt cgatagtacc gaattgtgtg acaggaagtt ctccgttaaa ccattgcttt
     8401 ttcccctccg ttagtgttac ttgtgctttg ccgggcacat tataggcaat gccgtccacc
     8461 ttctttttgc catcgtcttc cggtacgttg acggttttca gattcttcag cgtgatataa
     8521 accggctctc ctgcaagatc gttattggca actatgccca gcttcttcga aaagcggaag
     8581 gctacttcgt tgtccatttc cttatccgga gtgaggcgga tgttgaatat cttttcgtct
     8641 ttattcaagg tacccgagaa catttcggtc atggcagcct cttgctcttc caggttggcg
     8701 agcataatct tcagttgctc cccatctttg ggcatgttgt ctgcctgtcc gcgtaccagg
     8761 gcatttttac tttcacgaat gttataaatc tctttggcaa ctaactccgc cattttagcc
     8821 gtagaacctg ccatcagaat ctcttcggtc agaaaatcac gtggatttat cttctttttc
     8881 tgtgtcgtgg cgggttgcat cggagccgac tttttaggag atagcggtac gttgattgat
     8941 tttacgatac catcttcggt caattctatt agcggagcta cagttttatc tttcagcttg
     9001 acaaaatagg tatgttcgct atcggggata ccgacagatt ttgctttgac gctgaccagt
     9061 tcccaatatt cctgaggctc acccgacaca tcggtcaacc ggagataacg gtcggcatac
     9121 ttgctgaatt ctcccggagt atatgtcact ttattgactt tgacttcaat attgattgct
     9181 gttttaggaa gtgcataggt tacaccgtaa tcttttcccc gggtaactcc cgctgtaact
     9241 tcggtctggg cataagccga ggtagagagt aacagccctg tcagtataat tagctttttc
     9301 atttccggtt tattttaact ggtttaaaaa acaaagttaa tgaagttatt tggaaaatca
     9361 taagttgtta acttttattc gcttaccaga cgccaagcca atggcagatt actgataatg
     9421 tctcctgccg tcatgctgat aacgccttgc tttttgcgtg cgaaatcacc tgccagacca
     9481 tgtacataag taccgatttt ggcagcttct tcagccggat atccctgtgc gagcaaagcc
     9541 agcacgacac ctgtcaatac atctccgctt ccggctgttg ccatacccgg attacccgta
     9601 gagttgaaat agcacttgcc cgagggggtg ataattgccg aataggctcc ttttaatatg
     9661 atatgtactt tggcggttcg ggccagttca caggccttca tcagtcgttc gtatgagttc
     9721 tggcatttgc ccaccatgcg ttccagttct ttgggatggg gagtcagaat agagcctttg
     9781 ggcaatgtgg tcagtgcgtg gcggtggttg gccaatatgt ttagtgcatc ggcatccagt
     9841 accagaggtg tctggcaacc actgagttgt tcaagcagtg cagcttcggt ctcttccgag
     9901 cgtccgatgc ccggaccgat tcctacagcc tgatagtcat ccgtatctgt agggcaggca
     9961 aagtaggtat cgctggcatc cgattcgata attgcctccg gaaccgaaat ctgcaggata
    10021 tcattgttac gtatgggtgc atggactgtc agtaagccta cacccgaacg catacaggcg
    10081 cgggctgcca gtatcgacgc gcctgccatg ccgtacgaac cggcaatcag cagagcatgc
    10141 ccaaagtttc ctttgtgtga gaaagtgtta cggggtttga tcagagcgtg tatttcttcc
    10201 gcttccaata aggcataatt gctttccgtc tcttcaatcg cttcacgact gaggttgata
    10261 tccaacagtt tccattcgcc tacgaattcg gaattttcag caaagaggaa agccagtttc
    10321 ggcaattgca ggctcaatgt caattgggca cggatgatat tggcttttac attaaatgtg
    10381 ttctcttctc ccatcagtcc cgaggggata tcgatggcga ctacggtggc aggcgatgca
    10441 ttgatatatt tcactactgc cgcaaa
//
