LOCUS       gnlProkkaGPCMMPKA_433   6958 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GPCMMPKA_433.
ACCESSION   gnlProkkaGPCMMPKA_433
VERSION     gnlProkkaGPCMMPKA_433
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 09:52:53
            Original ID  :: gnl|Prokka|GPCMMPKA_433
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6958
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6958
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1:1958]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2..1958
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..6958
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6958
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(2..649)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg433_1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 7.6e-20, bitscore:
                     60.1, seeds: 75, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISPELFINSLVQNELNFFTGVPDSLLKHICAYITDHIASNSHIV
                     AANEGAAIGLAVGYHLATNKIPVVYMQNSGIGNSINPLLSLVDKEVYNIPLLLLVGWRG
                     EPGVKDEPQHIKQGKVTIPLFDSMRIKNQILSKDKSDFLQQLNVALEYIRETNEPFVFI
                     IQKETFSDYKLQTPNNNALLLDRETAIKIIVSSISKNDIVVSTTGMISRELFE"
     CDS             complement(657..1958)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 200.2;
                     E-value: 7e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg433_2"
                     /sec_met_domain="CTP_transf_like (E-value: 1.2e-16,
                     bitscore: 50.2, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 2e-119, bitscore:
                     386.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 8.9e-65, bitscore:
                     207.4, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKVYVGMSADIIHPGHLNIIHEAQKLGNVTVGVLTDAAIASYK
                     RLPYLTYEQRSLIVQNLKGVDEVIPQTTLDYIPNLELLKPDFVVHGDDWKEGVQKETRQ
                     RVIETLSKWGGQVIDIPYTQGISSTKLNSKLKEIGTTPEVRLKRLKRLIEAKSIVRICE
                     SHSGLTGLIIENTSVEVNGMKREFDGMWSSSLTDSTSKGKPDIEAVDLTTRLHDLNDAL
                     ECTTKPVIFDGDTGGKIEHFVFTVRTLERLGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCDKISAGKRAQITDDFMIIARIESFIAGKGLDDAMKRALAYIEAGADGIMIHSKD
                     KSGEDIRLFCKALREVNQSIPIVVVPTTYNHITDEELSTWGINVVIYANHMLRSAYPAM
                     LNTAKSILLHARSYEANDLCMPVKDILELIPGTK"
     CDS             complement(1961..2434)
                     /locus_tag="ctg433_3"
                     /transl_table=11
                     /translation="MTQIHELQHVAHELLYLGADGSPIYTDSFRQLNTEVLQKSDALFA
                     LKGENPEEEARLCLALLMGYNATIYDYGDKESKKQVILDRSLLVLESLPSSLLKCQLLT
                     YCYGEVFEEELAKEAHAIIDGWKDRELLEEEREIVENLRILEEPPYLFSNKSC"
     CDS             complement(2470..2988)
                     /locus_tag="ctg433_4"
                     /transl_table=11
                     /translation="MSQQQEYWFAARTRKDQELITRDALEKIGVEYFLPTQFVIRQLKY
                     RRRRVEVPVIRNLIFVHATKEFACAIANEYGVRLFYMRDFDTKSMLIVPDKQMKDFMFV
                     MNLDPAAVILNDDCFAVGTKVQVIKGDFCGVEGELASLSNRTYVTIRIRGVLSASVKVP
                     KSYLRILAP"
ORIGIN
        1 attcaaatag ctcacgagat atcattcctg tagtagaaac gactatatca ttcttagaaa
       61 tagaagaaac aataatctta atagcagttt ctctatccaa taacaaagca ttattatttg
      121 gagtttgcag tttataatca ctgaatgttt ctttctgaat tataaaaaca aaaggctcat
      181 ttgtctctct tatatattct aatgctacgt ttagttgttg taagaaatca gatttatctt
      241 tggaaagtat ctggttcttt attcgcatag aatcaaacaa aggaatagtt accttacctt
      301 gttttatatg ttgaggttca tcctttacac caggctcacc tctccaaccg actaataata
      361 ataaaggaat attatacacc tccttgtcta ctaaagataa taaaggatta atagaattac
      421 caataccgga attttgcata tatacaaccg gaattttatt agttgccaaa tgataaccaa
      481 cagccaaacc aatcgctgct ccctcattgg cagcaactat atgactattt gaagctatat
      541 gatcagttat ataggcacaa atatgtttca ataatgagtc tggtacccct gtaaaaaaat
      601 taagttcatt ttgtacaaga gagttaatga aaagttctgg agaaatcata aaaaaactat
      661 tttgtacctg gtattaattc taatatatct tttactggca tacataaatc atttgcctca
      721 tatgaacggg catgtaataa tatagatttc gcagtattta gcatagcagg ataagcacta
      781 cgtaacatat ggtttgcata aatgaccaca tttatacccc atgtagacaa ctcttcatct
      841 gttatatgat tataagttgt cggaactact actataggaa ttgattgatt aacctctcgt
      901 aacgccttac aaaaaagtct aatatcttca cctgatttat ctttactgtg aatcattata
      961 ccatcagctc ccgcctcaat ataagctaat gctcttttca tagcatcatc taaaccttta
     1021 ccagcaataa aactttcaat tctggcaata atcataaagt catccgttat ttgagcacgt
     1081 tttcctgctg atattttatc gcaaaaaccc tcaattgtat cttgtgtctg aataacatca
     1141 gttccaaata aagaattctt tttcaatcca actttatctt caattattat agcagaaata
     1201 cccaaacgtt ctaacgtacg aactgtaaaa acaaaatgtt caatttttcc tcctgtatca
     1261 ccatcaaaaa taacaggttt cgttgtacat tccaaagcat catttaaatc atgtaaacgg
     1321 gtcgtcaaat ctacagcttc aatatcaggc ttcccctttg atgttgaatc agttaaacta
     1381 ctagaccaca ttccatcaaa ttcacgcttc ataccattta cctcaacaga cgtattttct
     1441 atgattaacc ccgttaatcc actatgtgat tcacaaatac gaacaatgga cttagcttca
     1501 atcaaacgtt ttaatctttt caaacgcact tcaggagttg tccctatttc tttaagcttt
     1561 gaattgagtt ttgttgagga tataccttgt gtataaggta tatcaataac ttgtccgccc
     1621 catttagaaa gagtttcaat aacccgttgt cttgtttcct tctgaacgcc ttctttccaa
     1681 tcatctccat gaacaacaaa atcaggtttt agcaattcaa gattaggaat ataatctaag
     1741 gtagtttgtg gaataacttc atcaacacct tttagatttt gtactattaa ggaacgttgt
     1801 tcataagtta aataaggtaa acgtttataa ctggctatag cagcatctgt taaaacacct
     1861 acagtcacat tccctagttt ttgtgcttca tgaataatat tcaaatgccc tggatgaata
     1921 atatcagcac tcatcccaac atatactttc tttttcattt ctaacaagat ttattactaa
     1981 acagatatgg aggttcttcc aaaatcctca aattttcaac tatttctctt tcttcttcta
     2041 acaattctcg atctttccaa ccatctataa ttgcatgagc ttcctttgcc aactcttctt
     2101 caaaaacttc tccataacaa tatgtcaaaa gctgacactt gagcaaagaa gacgggagag
     2161 actctaacac aagcaaggaa cgatccagaa taacctgttt cttagactcc ttgtcgccat
     2221 aatcatagat tgttgcattg tagcccatca agagagccag gcaaagtcgt gcttcttctt
     2281 ccggattttc tcctttcaaa gcaaacaaag catcagattt ttgaagcact tcagtgttta
     2341 attgacggaa actgtcggta tagataggag aaccgtcagc acccaaatac aataattcgt
     2401 gagccacatg ttgcagctca tgaatctggg tcataagagt attcatttta tatgataaaa
     2461 tattactgat tacggtgcga gaatgcgaag gtagctttta ggaaccttga cactggcaga
     2521 taaaacgcca cgaattcgga tagtgacata agtacgatta gaaagactgg ccagttcacc
     2581 ttcaactcca caaaaatctc ccttgatgac ttgtactttg gtaccaactg cgaaacaatc
     2641 atcgttgagg ataacagcag caggatcgag attcatgaca aacataaaat ctttcatctg
     2701 cttatcggga acaataagca tactcttagt gtcaaaatca cgcatataga aaagacgcac
     2761 cccgtattca ttggcaatag cacaagcaaa ctctttggta gcatgtacaa aaataagatt
     2821 acgaatgaca ggaacttcta cacgacgccg gcgatatttc aattgacgaa tgacaaattg
     2881 ggtcggcaaa aaatactcga cacctatttt ctctaatgcg tcacgagtaa taagctcctg
     2941 atccttacgg gtacgggcag cgaaccaata ttcttgttgt tgagacattt agaaggatat
     3001 attcctgagt gatttactta agtccgggta tgcttcgcag ttgggtgaga ctctttttct
     3061 cagccaaact gcaagatttt ttatgactta ttttaggtgg aaacgaacgg attcgatcaa
     3121 ttgatgtttc aaaaaacgtt cgtcttttga aacatcaatt atggagataa aagcccacat
     3181 acaaaataag taaaaagctg tttttattac cagattatta tctgataatc agtacataaa
     3241 gaagtctatt tagtttttca tctaaaaata ttttgcacat caaaatttag tttatacctt
     3301 tgtgctatta aacgaacgtc ttttgaaaca cattcactac tgactatcag ttaattacaa
     3361 gagaattcac tctttttatc cttttcgcat ttaccacaca acagactgat tataaacaaa
     3421 ttacacaata agataaactc ttcattattc tatctataaa gatttagaaa ctatatactc
     3481 ccaaaagcat tctgtcacat tgtattttga gtagcctcag gaatccctta tttacggacc
     3541 actgactaag ttgttataaa aaacaccggg attctatttt caccaaaatc atatctccac
     3601 caaataaatc aaatcaccag tcaaaagatc gataaacatg cactaatttc aatcagtaag
     3661 caacggaaaa ggcatcctat acctccaaaa taacattcag gaatgattca tattgaccta
     3721 tgctacagaa aagaattcta tagtttttgt tcaataaatg aaaccgccag gcaaaaagta
     3781 ggaggatttt caatgaaaat gaatttcgta actatacgaa gttaacttcg tattttctta
     3841 taactaactt cttcttcaca agaagttaat gttttgcaaa gacgaagtta acttcgtatg
     3901 aagagtacac ttatgaagaa acgaattaaa gacaagttaa tgctccatca tttgctattt
     3961 catcactttc tcaagacaac aaggttttta aaacaagaaa gaagccgact taaagatatc
     4021 agaatctcta ttttactatc agaataacag aagaggcaaa cttaatgagg aatggaaaaa
     4081 gaagtcgacg agagataaaa cccttacctc tcgtcaacca atactatttt tatgatcgtg
     4141 atacttggaa tcccttatca gataacatca tttcgacaaa acgtgcccgt ggattcggag
     4201 cgttttctgt cagtatctta cgaatacgaa cagcagcttg cggatctttc gctaccatat
     4261 ataagtaccc gccaccaccg gctcccggca atttatatcc caaggtataa tcttttatca
     4321 gatcgataat tgcctccaca gccggaggat ttgttccgct atccaatgct ttgttttgtt
     4381 cccaggtttt tcctaccaaa cggccaaact caacaaaact tccacgctgt atagcttcat
     4441 tcatatccaa tgcatgcgcc ttcatttccg agagtaaatt gagatgcaac gatgaattga
     4501 ggaacatgga actgactatt tctgccaaga tcccttttgc cgtacgagtt ataccggtat
     4561 aataaagcaa gtgacagtct ttgtattcag gatgcgtaaa taaatgatcg ggtagccaac
     4621 gcaccaatgg actttgagca aagccggcct cggtctgaag aagcttcaca ccctgcaaca
     4681 cacctccata ctgatcctgc catccaccgc cggtagtcag caattgttca agaacaagag
     4741 tacgttgaca aatctcattt ttatcccagg ctaaaccaca gaaatcgtta atggcaccaa
     4801 gtacggtaga agccagaatg gaactggtgc ccaaaccgga accggcagga atagcagcta
     4861 ataaagtcac ttcaatacct gcaccgaaat ctttaagctg ttcctctaat gaagcataag
     4921 atacagcaga aaacgcaggt gcaaagcctg ccaatgacag agcagctttc ggaatagaga
     4981 aaggtgaacc gatcttctta taatcttgca attcatcaaa cgtagatact atttccatag
     5041 cacccatatc gatagaacgc aggacgatat ggaaatcttt acacggcttc acatagacct
     5101 gtaagggagg ttgtccgttc aactcaatag ccagattcac cacatttcct cccgaataaa
     5161 gtgaataagg aggagtatcg gtccatccac ctgccatatc gatgcgcacg gggctacgtc
     5221 cccaaacaat ctgatcggaa tatacatcca attttggggt actcttacga ttactgatcc
     5281 cgtccagcaa gccgtcacga agcaaatcaa aagcagcctg ttcttccgga cgataatctt
     5341 tcccgtctaa tttcaaaata cgcgcacgca acatccggtt atggatgcgt gacatctgca
     5401 gagcatcctc aggcaataat tcaggcatat ccaaaccaag acgtacaaaa tcttcagctg
     5461 catcggccaa atcaagttga taaaaaacac ttttttcatg attaacggcc aatgctttcc
     5521 agtttccttt tctgaactct tcacgttgtg catacaaacg cttcagattg gcacctgccg
     5581 aaatttcgtc cgcagaaaaa tgttcggaac gtaaccagat attctttcct tcctccagtt
     5641 cgggttcgga caacatccac ctcaacacca atcccaactc ttctacagaa ttaaccatag
     5701 ggaatacgga agctgcctgt aaatcgtccg tacgtccttt caaatctgta tatgacaaac
     5761 cgcgtttgga catccattca ccaaaaggaa tacccgtcag ggttgttttg gaatctctca
     5821 aatctccttt gaaaacatcg tccaggccgt atggacgggc aacaaagccc ttatcaccca
     5881 tcggaaccac atctacacac actccggcag gcacagccaa cgaccagtca ttttccggaa
     5941 ccccggtaat aatatgtcgt gaagcaatct tccactttgg tccgatatga ctgttctcga
     6001 tccataaatc agcattctcg gcacaaagag gtatccgcac tacagcattt tggacaaaca
     6061 tagccggatt gggctttact ttacggtgca tgatacgacg ctgatcgtaa accttattct
     6121 gtacggaaag agttgaagat atcagttctt tactggtccc gtaatggtag aactctcctc
     6181 ccggcaaagg cagaatagca acggatagcg tattgacctc ttcgtcttca atacggggat
     6241 gagttcccaa agctaatcca aaatcggaat aaagatcata atactttagt tcttcagagc
     6301 tttctttatg agaacgtttt atcaagattt ctacggcacg gtcactcaaa agccatatac
     6361 cgatgtccat caggaacaaa tgggtcttcg ataaagattc caattctgcc aacgaaggct
     6421 tctgaagcat aaagtcgagt tgttcgggat gtttgcgatc ggaagcaaac acgccatgat
     6481 gggtagccag agacggatct acccacagtc cataacaaac cacatccgct tcgggaatac
     6541 tctgcaaagg tttctccgaa cgaatataga catcaccact cgcaatcagt gtatggagtt
     6601 tatccggagc caaagacatg attttttcat ataggggaag ttgcagagaa agcagatttt
     6661 gtcccagatg ttgccctctc tcccaccgga acacaggaac cggagtgaga atctttccag
     6721 aaggtgcata gccgggtaaa cgacggcttt gtccacccgc atgaagaaga attctttttt
     6781 ctttttcaag ccactctcca aaagtagcac catctgaata ttcattataa cattcttcaa
     6841 gcagccagga tgttccacca ccggaaccaa gtttcttacc taccgggtcg gaagtacaaa
     6901 accaatcggt acggttcacc ctctccagtt catgaaaaga ctgaaccaga ttgggcgg
//
