LOCUS       c00221_gnlPro..        15579 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GPCMMPKA_221.
ACCESSION   c00221_gnlPro..
VERSION     c00221_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 07:01:22
            Original ID  :: gnl|Prokka|GPCMMPKA_221
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15579
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15579
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2024:5579](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2025..5579
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..15579
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15579
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             231..1409
                     /locus_tag="ctg221_1"
                     /transl_table=11
                     /translation="METFYRTHAYLVEHTNAPVRRDLMDEINWSDRLIGIKGTRGVGKT
                     TFLLQYAKEKFGTDRSCLFINMNNFYFSGHSIVDFANEFQKRGGKVLLIDQVFKHPDWS
                     RELRMCYDRFPNLKIVFTGSSVMRLKEENLELRDIVKSYNLRGFSFREFLNLQTGMKFR
                     HYTLEEILSSHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENLLKTMNMMVE
                     VDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDIQTSRATVMNYIKYLADAR
                     LINLVYPKGEEFPKKPSKIMLHNPNLMYSIYPVKVEEQDVLDTFFVNTMWKDHKVHKGD
                     KNTSFMVDEVMPFKICCEGAKIKNNPGVTYALHKAEIGRGNQIPLWMFGFLY"
     CDS             1428..1988
                     /locus_tag="ctg221_2"
                     /transl_table=11
                     /translation="MDYEKLEQLKRLHDSGALNDEEFEKEKKKILDEEAAAKPTAVLPM
                     GLTENAYLALMNFAMFIPYVGWIAPIVFWIMGKENSILVNRQGKYILNWYISWFLYGIA
                     LTVLFVIFMFSGILSINDMDYANDQTSPLAVLLGIFGGGAGILLLLILGIGCFLCLLFP
                     IIGGIKGLNGKTWKYPLSIPFLK"
     CDS             2025..5579
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg221_3"
                     /sec_met_domain="PFOR_II (E-value: 1.7e-19, bitscore: 60.0,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1.3e-82, bitscore: 266.8,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 2.9e-32, bitscore: 101.9,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 7.8e-13, bitscore:
                     38.3, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.3e-12, bitscore: 37.6,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 5.4e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.3e-05, bitscore: 14.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 5.4e-26, bitscore: 80.1,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KARVPFMNFFDGFRTSHEIQKIEMLENEDLAPLVDQEALAEFRARALNPMNPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDYLTSQGEKVGLVAVHLYRPFSAKHFLAAVPKTAKTIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIIAVFKNLAMPMPKNHFTIGIVDD
                     VTFTSLPQEAEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDDPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAQEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKVENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGANFEMLKAVGKQFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAQADNWTYCADNVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLYGDREMVANATGCSSIYSGSVPSTPYTTNAKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARIVKLFNEILAADNAPAEAKEVLKAWIENMYDADKTKE
                     LAPQIEAIIEQGIAAGCPISKELKGLTQYLVKRSQWIIGGDGASYDIGYGGLDHVIASG
                     KDVNILVLDTEVYSNTGGQSSKATPVGAIAKFAASGKRVRKKDLGLMATTYGYVYVAQI
                     AMGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLW
                     RYNPALEAEGKNPFTLDSKEPNWDDFKGFLKGEVRYASVMKQYPAEAEELFQAAEDNAK
                     WRYNNYKRLANQAWGAAE"
     CDS             5714..6289
                     /locus_tag="ctg221_4"
                     /transl_table=11
                     /translation="MFKRKIFSVRLCVTLWCPPKNGIIMNITIRPTRLEELGQVMPFYE
                     RARRFMAANGNANQWINGYPSPDDIRQDIENGSSYVFVNENQELEGCFAFIRGEDPNYK
                     VIKDGAWLNDAPYGVIHRIASGGRVKGLMDLCLKWCSSHCPNLRVDTHRDNKVLQNILL
                     KNGFTYCGIIYVKNGTERLAYQRTAVTR"
     CDS             complement(6331..7158)
                     /locus_tag="ctg221_5"
                     /transl_table=11
                     /translation="LLLLAVMCVACNPDSGKKKISIAYANWLEGIAMSHLVKVVLEEKG
                     YEVELLNADVAPVFASVSRKKADVFMDAWLPVTMKDYIDQYGDQIEFIGEVYDSARVGL
                     VVPQYVTIDSIGELAAYKGQFSSEIVGIDAGAGIMKTTDKAIGDYGLDGYKLLTSSSST
                     MLASLQKAMEKEAWIVITGWTPHWMFDRYPLKFLHDPKGTYGNVESIYVVGWKGFTEKD
                     PFAAKFFSNIKFTTEEISSLMKALKDARMDEEDLVRKWRDEHRELVESWIPES"
     CDS             complement(7205..8029)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 96; E-value: 7.4e-30)"
                     /gene_kind="transport"
                     /locus_tag="ctg221_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.6e-30, bitscore:
                     96.0, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETLINWMMIHFSTFFDALNLGIGSFINGFQHILFGIP
                     FYLTIAAMVLLAWAKAGRGVAVFTLLGLLLIYGMGFWEATMQTLALVLSSTCLALIVGV
                     PIGVWTANSNRAEKVIHPILDLMQTMPAFVYLIPAVLFFGLGVVPGVFATIIFAMPPVI
                     RLTGLGIRQVPKNVVEASRSFGATRWQLLYKVQLPLALPTILTGVNQTIMMSLSMVVIA
                     AMIAAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIILDRITQGMVRRKDKK"
     CDS             complement(8026..9252)
                     /locus_tag="ctg221_7"
                     /transl_table=11
                     /translation="MSKITIKDLYLIFGNDKQHALRMLKEEKSKSEILKATGCTVAVKD
                     ANLSIWEGEIFVIMGLSGSGKSTLLRCINRLIKPTSGEVIINGRDISNVTDKELLRIRR
                     KELAMVFQHFGLLPHRSVLHNIAFGLELQGVKKQEREQRAMESMQLVGLKGYENQMVGE
                     LSGGMQQRVGLARALANDPEVLLMDEAFSALDPLIRIQMQDELLALQSKMKKTIVFITH
                     DLNEAIKLGDRIAIMKDGEVVQVGTSEEILTEPANAYVERFVQSVDRSKIITAASVMVD
                     KPLVARLKKEGPEVLIRKMLERNLTVLPVVDANNVLVGEVRLKDLLRLRQDQVKSIESV
                     VREEVHSVLGDTILEDILPLMTKTNSPIWVVNETREFQGVVPLSSLIYEVTGKNKQEIN
                     EIIQNAIEL"
     CDS             complement(9587..9931)
                     /locus_tag="ctg221_8"
                     /transl_table=11
                     /translation="MKDYKENKSNLSETFCNEVYSVVREIPAGSVTTYGDIAALLGMPQ
                     YSRMVGRALRQVPAGLNLPCHRVVNAIGRLVPGWDEQRRLLDAEGVSFRKNGCVDLRLH
                     RWRDDSVLAD"
     CDS             complement(9962..12685)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg221_9"
                     /sec_met_domain="Peripla_BP_1 (E-value: 3.4e-16, bitscore:
                     49.2, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRILFLLGLMLSGLLVSCSPDAPRYTIGVSQCSDDTWRHKMNDE
                     IQREALFYGGVKVETRTAHDDSRRQIEDIRYFIRQKVDLLIVAANEGMALTPVVEEAFD
                     KGIPVIMVDRRILSDKYTAYIGADNYELGKAVGNYIAHRLKGRGKVVELSGLVGSTPAI
                     ERHQGFMSAISQYPDMTLLASEDAGWLQQPAEAKMDSLLQRFPEIDAVYGMNDRMAAGA
                     FRAAGRRGREKEMIFVGIDALPGKGNGVELVLDSVLDATFIYPTEGDKVVQLAMDILEK
                     KPFERETKLKTAVVDAVNAHVMELQTNHIGELDGKIETLNDRVGIYLSRVATQRIVLYG
                     GLIILLLIVGLLIVVYKSLRSKNRLNRELSRQKEQLEEQRDQLIELSHQLEEATHAKLV
                     FFTNISHDFRTPLTLVADPVEQLLADPSLEGDRRRMLLLVQRNVQILLRLVNQILDFRR
                     YETGKMEFTPVPLDLLQCFVEWNDSFQAAARRKHIHFSFDSVPDTDYHTQADAEKLERI
                     YFNLLANAFKFTPENGKVTVRLAALQKDGAPFFRFTVANTGSLISAEHIRSIFDRFYKI
                     DRHHTGSGIGLALVKAFVEIHGGSISVESDERLGTVFTVDLPVRTCEEGACVVTASMEE
                     SAPDRVDSLLREDEAENLNDPSKPSVLVIDDNADIRAYVHTLLNSEYSIIEAADGTEGI
                     RKAMKYVPDVIISDVMMPGIDGIECCRRLKGELQTCHIPVILLTACSLDEQRIQGYAGG
                     ADSYISKPFSSQLLLTRIRNLIESRQRMKQFFGDRQTLAKEDICDMDKDFVERFKSLIE
                     VKMGDSELNVEDLGKEMGLSRVQLYRKIKSLTNYAPNELLRMARLKKAASLLASSDMTI
                     AEVGYEVGFTSPSYFAKCYKEQFGESPTEFLKRSGL"
     CDS             complement(12869..13759)
                     /locus_tag="ctg221_10"
                     /transl_table=11
                     /translation="MNSIIVGMGEALWDVLPEGKKIGGAPANFAYHVSQFGFDSRVVSA
                     VGNDELGDEILEIFREKQLKHQLERVNYPTGTVQVTLDNGGVPCYDIKEGVAWDNIPFT
                     DDLKRLALSTRAVCFGSLAQRDEVSRATINRFLDTMPDMEGQLKIFDINLRQNFYTKEV
                     LRESFRKCNVLKINDEELIIISRMFGYPGIDLQDKCWILLAKYNLKMLILTCGTNGSYV
                     FTPGTVSFQETPKVPVADTVGAGDSFTAAFCSSVLKGKSIPEAHRLAVEVSAYVCTQSG
                     AMPVLPEALRNRLND"
     CDS             complement(13791..14957)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 112.6; E-value: 6.3e-35)"
                     /gene_kind="transport"
                     /locus_tag="ctg221_11"
                     /sec_met_domain="MFS_1 (E-value: 1.3e-35, bitscore: 112.6,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENTKNNSYMKLIPVMLCFFAMGFVDLVGIASNYVKADLGLTDSQ
                     ANIFPSLVFFWFLIFSVPTGMLMNRIGRKKTVLLSLVITFASLLLPVFGDSYLLMLVSF
                     SLLGIGNALMQTSLNPLLSNIVSGERLASTLTFGQFVKAIASFLAPYIAMWGAIEAIPT
                     FDLGWRVLFPIYMVVAVVAILLLNATQITEEPEEGKPSTFGQCLALLGKPFILLSFLGI
                     MCHVGIDVGTNTTAPKILMERLGMTLADAGFATSLYFIFRTAGCFLGAFILQKMAAKTF
                     FAISVLCMLAAMFGLFVFQDQAMIYVCIALIGFGNSNVFPIIFSQAMLYMPDKKNEVSG
                     LMIMGLFGGTIFPLAMGVASDAVGQSGAVAVMLVGVLYLMFYTWRIKK"
ORIGIN
        1 cactgaagta gacaagcaaa atcacaattg cccgattaaa atggctgcgt tttttcagaa
       61 gcagcttgcc attgccccga aataacgtcc ctgccaccta tcaggaatac cgttttgaca
      121 aagtgaagca aaagataaac ttgctaaacg gaaccacaat tttgctatct ctactttgca
      181 atttctaaaa aaaggcttat atttgccccc cgaaaaaccc aagataagag atggaaacat
      241 tctaccgcac acatgcctac cttgttgagc acaccaatgc cccggtccgc cgcgacctga
      301 tggacgaaat aaactggagt gaccgcttga ttggtatcaa aggaacacgt ggcgtgggaa
      361 aaaccacttt cctgcttcaa tacgccaagg agaagttcgg aaccgaccgt tcgtgcctct
      421 ttatcaacat gaacaacttc tacttctccg gacacagcat tgtcgatttc gccaatgaat
      481 ttcagaaacg cggtgggaag gtactgctga tcgaccaagt attcaagcac cccgattgga
      541 gccgcgagct acgtatgtgc tacgaccgtt tccccaacct gaagattgta ttcaccggtt
      601 cgtccgtcat gcggctcaaa gaagaaaacc tggaattgcg tgacatcgtg aagagctaca
      661 acctccgcgg tttttcgttc cgcgaatttc tgaacctgca aacagggatg aaattccgtc
      721 actacacact cgaagagata ttgagcagcc acgaacagat agccaaaggg gtgctttcca
      781 aagtccgccc tctggattat tttcaagact acctccatca cggcttctac cccttcttcc
      841 tcgagaaacg caatttctct gaaaatctgc tcaagaccat gaacatgatg gtagaagtag
      901 atatcctgct tatcaaacaa attgagctaa aatatctctc gaagataaaa aaattattat
      961 atttgttggc tgtagacggg ccaaaggctc cgaacgtaag ccaactggca agcgacatac
     1021 agacatcacg cgccacggtg atgaactaca tcaagtatct ggccgacgca cggctgatca
     1081 acctggtcta tcccaaaggg gaagaattcc ccaagaaacc atcgaagatt atgctgcaca
     1141 accccaatct gatgtattcc atctaccctg taaaggtgga agaacaagat gtgctggaca
     1201 ctttctttgt aaacacgatg tggaaagacc ataaagtgca caaaggtgac aaaaacacct
     1261 cgttcatggt agacgaagtg atgccgttca aaatatgctg cgaaggagca aaaattaaga
     1321 ataaccccgg agtgacgtat gctttgcaca aggcagaaat aggtcgtggc aatcagatac
     1381 cactctggat gttcggcttt ttatattaac atcaaatctt gaacattatg gattacgaga
     1441 agcttgaaca actaaaacgc ctccacgaca gcggagcgtt gaacgatgaa gagttcgaaa
     1501 aagaaaagaa aaagatattg gacgaagaag ctgcggctaa acctacagcc gtacttccta
     1561 tgggactgac ggaaaatgct tatctggcac tgatgaattt cgccatgttc ataccatacg
     1621 taggctggat tgcccctatt gtattctgga tcatgggtaa agagaattct atactcgtca
     1681 atcgccaagg caaatacatt ctgaattggt acatcagttg gttcctgtac ggcatcgcgc
     1741 tgacagtact ttttgtaata ttcatgttca gcggcatctt atccataaac gacatggatt
     1801 acgcaaatga tcagacttct ccgttagcag ttctgctggg tatattcggc ggaggtgccg
     1861 gaatcttgct cctcttaata cttggaatag gctgctttct ttgtctgctg ttccccatca
     1921 tcggaggcat caaaggactg aacggaaaaa catggaagta tccgctttcc ataccgtttt
     1981 tgaaataaac aaataaatta cttacttaaa tattattttt agttatgact aaacagaaga
     2041 aattcatcac atgtgatggt aatcaggctg ctgcacatat ttcatatatg ttctcagaag
     2101 tagctgccat ttaccccatc actccctctt ctacaatggc tgaatacgta gacgaatggg
     2161 ctgccgcagg acgtaagaac atcttcggcg aaacagtatt ggtacaggaa atgcaatctg
     2221 aaggtggtgc agccggtgct gttcacggtt ctcttcaggc cggtgcactg actactactt
     2281 acactgcttc tcagggtctt cttttgatga tcccgaatat gtataagatt gccggtgaat
     2341 tcctgccttg cgtattccat gtatctgctc gtacactggc ttctcacgca ctgtgtattt
     2401 tcggtgacca ccaggacgta atgtctgcgc gccagacagg tttcgctatg ttggctgaag
     2461 gttctgtaca ggaagtgatg gacttggccg gtgttgcaca ccttgccaca atcaaagccc
     2521 gtgttccttt catgaacttc ttcgatggtt tccgtacttc acacgaaatc cagaagatcg
     2581 aaatgctgga aaatgaagac cttgctccgc tggttgacca ggaagcgctt gccgaattcc
     2641 gtgcacgtgc gctgaatccg atgaatccgg ttgcccgtgg tatggccgaa aaccctgacc
     2701 acttcttcca gcaccgcgaa tcatgcaaca actactatga agctgttccc gccatcgtag
     2761 aggaatacat gaatgaaatt tctaagatca caggtcgcaa atacggtttg ttcgattatt
     2821 acggagcaga agatgcagaa cgcgtaatta tcgctatggg ttctgtaaca gaagctgctc
     2881 gcgaagctat cgactatctg acaagccaag gagaaaaagt cggtttggtt gcagttcacc
     2941 tgtaccgccc gttctctgct aaacacttcc tggccgccgt acctaaaaca gctaaaacaa
     3001 tcgcagtact cgatcgcaca aaagaaccgg gtgctaacgg tgaacctctg tatctggatg
     3061 ttaaagactg cttctatggc gcagaaaatg ctccggttat cgtaggcggt cgttacggtc
     3121 tgggttctaa agatactact ccggcacaaa tcatcgccgt attcaagaat ctggctatgc
     3181 cgatgccgaa gaaccacttc acaatcggta tcgtagacga tgtaaccttc acttctcttc
     3241 ctcaggaagc agaaatcgct ctgggtggcg aaggtatgtt cgaagctaaa ttctacggct
     3301 tgggtgctga cggtacagta ggtgccaaca agaactcagt gaaaattatc ggtgacaaca
     3361 cagataaaca ctgtcaggca tacttctctt acgactctaa gaagtcagga ggtttcactt
     3421 gctctcacct gcgtttcggt gacgatccta tccgttctac ctatctggta aacactccga
     3481 acttcgtggc ttgccacgtt caggcttacc tgcacatgta cgacgtaacc cgtggtctgc
     3541 gtaagaacgg ttcgttcttg ctgaacacta tctgggaagg cgaagagctg gctaagaacc
     3601 tgcctaacaa ggtgaagaaa tactttgcac agaacaatat ctctgtatat tatatcaacg
     3661 caactcagat tgcacaggaa ataggtttgg gcaaccgtac caatactatc cttcagtctg
     3721 cattcttccg tatcacaggt gtaatccctg tagaccaggc tgtagaacag atgaagaagt
     3781 ttatcgtgaa gtcttacggt aagaagggtg aagacgttgt aaacaagaac tacgcagccg
     3841 ttgaccgcgg tggcgaatac aagactttga ctgttgaccc ggcttgggct aacctgccgg
     3901 acgatgccaa ggttgaaaac aacgacccgg cattcatcaa cgaagtagtt cgccctatca
     3961 atgctcagga cggagactta ctgccggtat ctgcattcaa aggtatcgaa gacggaacct
     4021 ggtatcaggg aacttctaaa tacgaaaaac gcggtgtagc tgctttcgta ccggaatgga
     4081 acgcagaaaa ctgtatccag tgtaacaagt gtgcttacgt ttgtcctcac gcttctatcc
     4141 gtccgttcgt actcgacgct gaagagcaga agggtgctaa cttcgagatg ctgaaagctg
     4201 taggtaaaca attcgacggt atgacattcc gtatccaggt tgacgttctc gactgtctgg
     4261 gttgcggtaa ctgtgccgac atctgtccgg gtaacccgaa gaagggtggc aaggctctga
     4321 ctatgaaaca ccttgaaagc caattggctc aagctgataa ctggacttac tgtgcagaca
     4381 acgtaaagag caaacaacac ctggtagaca tcaaggctaa cgtgaagaac tctcagttcg
     4441 ctactccgtt gttcgagttc tcaggagctt gttctggttg tggtgaaact ccgtatgtga
     4501 aactgatttc tcagttgtac ggtgatcgcg agatggttgc caacgctacc ggatgttctt
     4561 ctatctattc cggttcagta ccttcaactc catatactac caacgcaaaa ggacacggtc
     4621 cggcttgggc taactcactg ttcgaagact tctgtgagtt tggtttaggt atggaactcg
     4681 ctaacgaaaa gatgcgtgca cgtatcgtga agttgttcaa cgaaatcctg gcagccgaca
     4741 atgctcctgc agaagctaag gaagtattga aagcatggat cgaaaacatg tacgatgcag
     4801 ataagaccaa agaactggct ccgcagatcg aagcaatcat cgaacaaggt atcgcagcag
     4861 gttgcccgat cagcaaagag ctgaagggcc tgactcaata tctggtgaaa cgcagccagt
     4921 ggattatcgg tggtgacggt gcttcttacg atatcggtta cggcggtctc gaccacgtta
     4981 tcgcttcagg taaagacgtt aacattctgg ttctggatac agaggtttac tctaacacag
     5041 gcggtcagtc ttctaaggct actccggtag gtgctatcgc taagttcgct gcttccggta
     5101 agcgcgtacg taaaaaagac ctcggtctga tggctactac ttacggttat gtatatgttg
     5161 cacagatcgc tatgggtgct gatcaggctc agactctgaa agctatccgc gaagctgaag
     5221 catatcccgg accatcactc atcatcgctt atgctccgtg tatcaaccac ggtctgaaag
     5281 ccggtatggg taagagccag gaagaagaag aaaaagctgt taagtgcggt tactggcact
     5341 tgtggcgtta caacccggct ctggaagcag aaggcaagaa tccgttcaca ctggatagca
     5401 aagaaccaaa ttgggatgac ttcaaaggct tcctgaaagg cgaagttcgt tatgcatcag
     5461 ttatgaaaca gtatcctgca gaagcagaag aactgttcca ggcagctgaa gacaacgcaa
     5521 aatggcgtta caacaactac aagcgtctgg ctaaccaggc ttggggtgca gctgaataat
     5581 ctttgatcag ataataactt tcgaaggggg aagggactaa aagaggttct ttcccccttt
     5641 ttgaacaaaa atgaataggt ttcaccacag agtaacacag agtctcacag aatttaaatt
     5701 tcttgttcat aggatgttta agagaaaaat cttctctgtg agactctgtg ttactctgtg
     5761 gtgccccccc aaaaacggaa taatcatgaa tataaccata cgccccaccc ggcttgaaga
     5821 actcggccaa gtgatgccat tctacgaacg tgcccgccgc ttcatggctg ccaatggcaa
     5881 tgccaaccag tggatcaacg gatacccctc ccctgatgat atccggcaag atatcgaaaa
     5941 cgggagcagc tatgtgtttg taaacgaaaa tcaagagtta gaaggctgtt ttgctttcat
     6001 ccggggagaa gatcccaact acaaagtcat caaagacggc gcctggctca acgatgcccc
     6061 ttacggggtg atccatcgca tcgcatccgg cggacgggta aagggattga tggacttatg
     6121 cctgaaatgg tgttcgtccc actgtccgaa cctgcgtgta gacactcacc gtgacaataa
     6181 agtactccaa aacattctcc taaagaacgg tttcacctat tgtggcatta tttatgtgaa
     6241 aaacggtacg gaacgacttg cctaccaacg cactgccgtt acccgataga cagaaatcag
     6301 aagttggatt cccggacaca catatactgc ttatgattca gggatccagc tttctaccag
     6361 ttcccgatgt tcgtcgcgcc attttcggac aagatcttct tcgtccatac gtgcatcttt
     6421 aagtgctttc atcaacgaac taatctcttc tgtagtgaat ttaatattgc tgaaaaactt
     6481 tgccgcaaaa ggatctttct ccgtaaatcc tttccatccg acgacataga tagattccac
     6541 attcccataa gtacctttcg gatcatgcag gaacttcaat ggatagcggt cgaacatcca
     6601 atgcggagtc catccggtga tgacgatcca cgcctccttc tccatagcct tctgtaaaga
     6661 agccaacata gtagagctgc tcgaggtgag taatttataa ccatcaagac cataatcccc
     6721 gatagcctta tcggtagttt tcataatacc ggctccggca tcgatcccga caatctcgga
     6781 agagaactgc cctttgtagg cggcaagttc cccaatcgaa tcgatagtga catattgagg
     6841 taccaccagc cctaccctcg cgctatcata tacctctccg ataaactcta tctgatcacc
     6901 gtattgatct atataatcct tcattgtcac aggtaaccag gcatccataa acacatctgc
     6961 cttcttacgg gaaaccgagg caaaaacggg agctacatct gcattcagca actccacttc
     7021 gtaccccttc tcttccagca ccactttaac cagatgactc atggcaattc cttccagcca
     7081 gttggcatag gcaatgctta tcttcttttt cccgctatcc gggttacagg ctacgcacat
     7141 cacagccagt aacaacaaac ttcctattat tctatatttt cgcatatcct attctttctc
     7201 ctttctattt tttgtccttc cgacggacca ttccctgagt aatccggtct aaaataattg
     7261 ccaatatgac aacggctata cctccttcaa agcccagccc gattttcatc tgggtgatac
     7321 ctttcaaaac gatttctcct aaaccgccgg cagcaatcat agccgcaatg acaaccatgg
     7381 aaagagacat cataatcgtc tggttcactc cggtcaggat ggtgggcaaa gcaaggggca
     7441 actgtacttt ataaagcaac tgccatcggg tagctccgaa cgagcgtgaa gcctctacca
     7501 cattctttgg cacctgacgg atgccaagcc ctgtaaggcg aatcaccgga ggcatcgcaa
     7561 agatgattgt agcaaatact cccggaacca ctcccaggcc gaaaaacaaa acagcaggaa
     7621 tcagatagac gaaggctggc atggtctgca tcaggtcgag aatgggatgt atcaccttct
     7681 cggcacgatt gctgtttgcc gtccatactc cgatgggaac ccctacgata agggccaggc
     7741 aggtggatga cagaaccagt gccaatgtct gcatagtggc ttcccagaat cccataccat
     7801 aaataagcaa caagcctaaa agggtgaaaa ctgcaacccc gcgtccggct ttcgcccatg
     7861 ccagcagcac cattgccgca atggtcagat agaaaggaat gccaaacagt atgtgctgga
     7921 atccattaat aaaactaccg atgcctaagt tgagtgcatc gaaaaaagtg gagaagtgta
     7981 tcatcatcca gttgatgagc gtctcaatat attgtcctat gttgatcata attctattgc
     8041 attttgaatg atttcattga tttcttgttt gttctttccg gttacctcgt aaataagcga
     8101 tgacaacgga acaactccct gaaactcgcg ggtctcgttc actacccaga taggcgaatt
     8161 ggtttttgtc atcaacggta aaatatcttc cagtatcgta tctcccaaca ccgaatgcac
     8221 ttcctcccgg acaaccgact cgatcgactt cacctggtcc tgacgcaatc ggagcaaatc
     8281 tttcagccgg acctctccca caagcacatt gtttgcatcg accacaggca acacagtcag
     8341 gttacgctcg agcattttac gaatcaacac ctccggtccc tctttcttca atcgggccac
     8401 aaggggttta tctaccatca ctgatgcagc ggtaataatc ttgctacggt ccacactctg
     8461 cacaaagcgc tctacataag cattggccgg ttctgtcagg atctcttccg aagtgcctac
     8521 ctgtaccacc tcaccatctt tcatgatagc aatccggtcg cccaatttaa tggcttcatt
     8581 caaatcgtgg gtaataaaca cgatggtctt cttcatctta gattgtaagg ccagcaattc
     8641 atcctgcatc tgtatgcgaa tcaaaggatc gagagcggaa aaagcctcat ccatcagcag
     8701 cacctcagga tcattggcca acgcacgggc caaaccgaca cgttgctgca tacctcccga
     8761 cagttcgccg accatctggt tctcgtagcc cttcagtcct accagttgca tgctttccat
     8821 cgcccgctgc tcccgctcct gtttctttac tccttgcagt tccagtccga aagctatatt
     8881 atgcaacacc gagcgatggg gcaacaaccc aaaatgctgg aacaccatag ccagctcttt
     8941 tcttcggata cggagcaatt ctttatcagt gacgttagaa atatctctcc cgttaatgat
     9001 cacttcgccc gaggtcggtt ttatcaatcg gttgatgcaa cgcagcaaag ttgattttcc
     9061 acttcccgaa agtcccataa tcacaaatat ttctccttcc cagatagata gatttgcatc
     9121 ttttacggcc accgtacatc cggtagcctt caatatctca cttttgctct tttcttcctt
     9181 caacatgcgt aaagcatgct gtttgtcatt gccaaaaatg agatacaagt ctttaatcgt
     9241 tattttactc atacataata gggtttagat tattaaaaaa acagatcggg tgacctatac
     9301 acacgaaaac aagcacttct ttatagcaag gaagttgatg ccggggaagc gacggttccg
     9361 ccgttccccg gtcaaatatg atttctttac ccgattatta cagacaggat tcctgtcaac
     9421 agatagttta ctatatcccg aaagtcaatt tcacatccgc acacagctat cttccaaaga
     9481 tgcgtatgca gacaattaag taaacaagcc gaacgttcaa atggttcatc gcattatttc
     9541 cggcaggcgc attacacgta cataaacccc tacaaaagag tcagtatcaa tcggccagca
     9601 cactgtcatc cctccacctg tgaagcctga ggtctacaca tccattttta cggaaagaaa
     9661 caccttcggc atccagcagc cgccgctgct cgtcccatcc gggcactaat cggcctatgg
     9721 cattgactac ccgatgacaa gggaggttta aaccggcagg cacctgcctc aaggcacgcc
     9781 ccaccatgcg tgaatattgc ggcatcccga gcaaagcggc aatatcgcca taagtagtaa
     9841 cactaccggc aggaatctca cgcacgacac tgtatacctc attacaaaaa gtttcggaca
     9901 aattagattt attttcttta taatctttca tggatgtatt gcttttatac agtgagttcc
     9961 tttataatcc gcttctcttc aggaactccg tcggactttc accgaactgc tccttgtaac
    10021 acttcgcaaa gtacgaagga gatgtgaatc ccacttcata tccgacctcc gctatcgtca
    10081 tatccgaaga agccaacaga gatgccgcct ttttaagacg tgccatgcgg agcaactcat
    10141 tgggagcgta gttcgtgagc gacttgatct tccgataaag ctgaacccgg ctcaacccca
    10201 tctctttgcc cagatcttcc acattaagtt ccgaatcacc catcttcacc tcgatcagcg
    10261 acttgaacct ctccacaaaa tctttatcca tatcgcaaat gtcttctttc gccagcgtct
    10321 gccggtcgcc aaagaactgc ttcatacgct gccgcgattc aatcagattt cggatacggg
    10381 tcaacaagag ttgcgaactg aacggttttg agatgtatga atcggctcct cccgcatatc
    10441 cctggatgcg ttgctcatcg agcgaacagg ccgtaagcag gataacggga atgtggcagg
    10501 tttgcagttc tcccttcagc ctccgacaac actctatgcc atcgatcccc ggcatcatca
    10561 catccgaaat aatcacatcg gggacgtact tcatcgcttt acggattcct tcggtaccat
    10621 ccgcagcttc aataatcgaa tactccgaat tgagcaacgt atgcacataa gcacggatgt
    10681 cggcattatc gtcgatcaca aggacagaag gtttggacgg atcattcagg ttttccgctt
    10741 catcctcgcg gagcaggctg tccacccggt ccggagcaga ctcctccatc gaagcagtca
    10801 ccacacaagc cccctcttca caagtccgca ccggcagatc gacagtaaag acagttccca
    10861 accgttcgtc actctccaca ctaatacttc cgccatgtat ctcgacgaat gctttcacca
    10921 atgccaaccc gatgccggaa ccggtatgat gcctgtcgat tttatagaac cgatcgaaaa
    10981 tgctgcgaat gtgttcagcc gaaatcaggc tgccggtatt ggccaccgtg aaacggaaga
    11041 aaggcgcgcc gtccttctgc agagccgcaa gacggacagt gacctttcca ttctccggag
    11101 tgaatttaaa ggcatttgcc aacaaattga agtaaatgcg ttccagcttc tccgcatctg
    11161 cctgtgtgtg ataatccgta tcgggaacac tgtcgaaaga gaagtggata tgtttccgcc
    11221 gggcagccgc ctgaaacgaa tcattccact ctacaaagca ttgcaacagg tcgagcggaa
    11281 ccggtgtaaa ctccattttt ccggtctcgt atctgcgaaa atcaagtatt tgattgacca
    11341 gacgcaatag gatctgcaca ttgcgttgca ccagcaacaa cattctacgc cggtcacctt
    11401 ccagcgacgg atctgccagt agctgttcca caggatcggc aaccaaagtg agaggagtac
    11461 ggaaatcatg tgaaatgttg gtgaagaaaa ccagtttggc atgggtagcc tcttccaact
    11521 gatgggaaag ttcgatcagc tgatctcttt gctcttccaa ctgctccttt tgccgtgaca
    11581 actcccggtt caggcgattc ttggaacgaa gcgatttata tactactatc aacaacccga
    11641 cgatcagcag caggatgatc aggcctccgt acaacactat ccgttgcgta gccaccctcg
    11701 agagatatat ccccacacgg tcgttcagtg tctcgatctt tccatccagc tcaccgatat
    11761 ggtttgtctg caactccatc acatgcgcgt ttaccgcatc gactacagcc gtcttcaact
    11821 tcgtttcccg ttcaaaaggt ttcttttcga gaatatccat tgccagttgc accactttat
    11881 ccccttcggt gggatagata aaggtggcat ccagtacgct gtcgagcacc agttccactc
    11941 cattcccctt acccggcagg gcatcgatgc ccacaaaaat catctccttc tcccgtcctc
    12001 gacgaccggc agcccgaaaa gcccctgcag ccatacggtc attcattcca tatacggcat
    12061 cgatctccgg aaaacgttgc aaaagggagt ccatctttgc ctcggcaggt tgttgcagcc
    12121 atcctgcatc ttcgctggca agcaaggtca tgtccggata ttggctgatg gcactcataa
    12181 acccctgatg gcgctcgata gcgggagtag aaccgacaag tccgctcagt tcgactactt
    12241 ttccgcgccc tttcaggcga tgggctatat aattgccgac ggctttgccc aactcataat
    12301 tgtcggctcc gatgtatgcg gtatatttat cggaaagtat tctgcggtct accataatca
    12361 ccggtattcc tttatcgaaa gcctcctcga caaccggagt aagagccatt ccttcattgg
    12421 ctgccacaat cagcaggtca accttctgcc ggatgaaata tcgtatgtct tctatctgac
    12481 gccggctatc gtcatgcgcc gtacgtgtct ctactttgac tcctccgtag aacaaagctt
    12541 cccgctgtat ctcgtcattc atcttgtgac gccaggtgtc gtcactgcat tgtgacacac
    12601 cgatggtata tcggggagca tccggactgc acgagacaag cagtcccgac agcatcagtc
    12661 cgagtaagaa aagtatacgg ttcatggtcg gttattacat aaaaggttcc ggaggcaaat
    12721 ataacaattt ccctccggaa tctcccacct gcttggttta aaaccaaagt cccgttggtt
    12781 taaaaggtga gttatgaaac actctcctga ttttaaaccc aacggaactt tctatcaacc
    12841 aatcaataac cctatataaa ccaacacatt agtcattcaa acgattcctc aaagcctccg
    12901 gaagtacggg catcgctcca ctttgggtac atacgtaagc agatacctct accgccagcc
    12961 gatgtgcctc agggatactc tttcctttta aaacagatga acaaaaagcc gctgtaaacg
    13021 aatcacccgc ccccacagta tcggcaaccg gaactttcgg tgtctcctgg aaagagaccg
    13081 taccgggagt gaatacataa cttccgttcg ttccgcaagt caggatcagc atcttcaggt
    13141 tatacttggc cagcagaatc caacatttat cctgcaggtc gatgccggga taaccgaaca
    13201 tgcggctgat aatgatcaat tcctcatcat taatcttcag cacattgcac ttccggaaag
    13261 attcacgcaa gacctccttg gtgtagaagt tctgacgaag gttgatatcg aatattttca
    13321 actgtccttc catgtcgggc atggtgtcga ggaagcggtt gatagtggca cggctcacct
    13381 cgtcgcgctg tgccaacgaa ccgaaacaga cagcacgtgt actcaaagcc agccgtttca
    13441 agtcgtctgt gaaaggaata ttatcccatg ccactccctc tttgatgtca taacacggca
    13501 ctccgccgtt atcgagagtc acctgcaccg ttccggtcgg gtagttcacc ctttcgagct
    13561 ggtgcttcaa ctgtttctcc cggaatattt ccagaatctc gtcacccagt tcgtcatttc
    13621 ctaccgcact gacaacgcgg ctgtcgaaac caaactgaga cacatgataa gcaaaattag
    13681 ccggggcccc cccgattttc tttccttcgg gcagcacatc ccatagcgct tcgcccattc
    13741 ctacgattat actgttcatg gtatgaatta atttttatct ataaatccgg ttatttcttg
    13801 attctccatg tataaaacat cagatagagt actccgacca gcatcaccgc taccgctccg
    13861 ctttgtccca cagcatccga agccactccc attgccagcg ggaagatcgt tccaccgaaa
    13921 agtcccataa tcatcaggcc ggaaacctcg ttcttcttgt ccggcatata gagcattgcc
    13981 tgcgagaaaa tgatggggaa tacattagag ttgccaaacc cgatcagggc aatacagaca
    14041 taaatcatcg cctggtcctg gaaaacgaac aacccgaaca tggcggccag catacacaac
    14101 acactgatag cgaagaaggt tttagccgcc atcttctgca aaatgaaagc tcccagaaaa
    14161 caacctgccg tacggaaaat gaagtaaaga ctggtcgcaa acccggcatc cgccagagtc
    14221 atgcccagac gttccatcag aatcttcggt gctgtagtat tggtacccac atcgatcccc
    14281 acatgacaca taatgcccaa aaacgagagc aggatgaagg gtttacccag caaagcgaga
    14341 cactgaccga aagtggaagg tttgccctct tccggttctt cggtgatctg cgtggcgttg
    14401 agtaacaaaa tagcgactac agccaccacc atatagatgg ggaacagcac tctccagcct
    14461 aagtcgaagg tagggatggc ctcaatagct ccccacatag cgatataagg ggctaggaag
    14521 gaggcgatgg cctttacaaa ctgcccgaag gtcagggtac ttgccaagcg ctcgccgctc
    14581 acgatgttcg acagcaacgg attgagcgat gtctgcatca acgcattgcc aatgccgagc
    14641 aacgagaaag agaccaacat cagcaaatag ctatcaccaa agaccggtag cagtaatgat
    14701 gcgaaagtga tcaccagact gagcaacacg gtctttttac gcccgatgcg gttcatcagc
    14761 atccccgtag gtacagagaa gatcaggaac cagaagaaaa cgagcgacgg aaagatgttt
    14821 gcctgtgagt ccgtcagtcc caaatctgct ttgacgtagt tggaggcaat gcccaccaga
    14881 tctacgaatc ccatggcaaa gaagcagagc atcaccggga tgagtttcat gtaagagttg
    14941 tttttggtat tttccatgat atgttaattt aatgaatgtc tcaacgggag gcgatagagg
    15001 aactacaacc tgtatatctt gcaccgatcc accttgaagg ctcccccacg actgtagaaa
    15061 ctcatctgat tgtaaggagt tgtagggaat atcaggttcg tcatagcaat cttacctccg
    15121 ttcaggaaga tttctaccga gcatttatct acaaagatat ccaatttata gttaccggct
    15181 ttctgcaccg gagcccaggt acccaaagca aaatcgtcta cataattaat agagttctgt
    15241 ttccggcgat cgtgtgcctc gatggcatgc ggggcactgt ctttgccgaa gtctacgatg
    15301 ccgctcttcg tacggtccat caccaacttt ttctccggaa ggctgatgta gatatccaca
    15361 ttctccccct tttcattgaa cagcttcagt cccataatct cggcagagcc ggctgccagt
    15421 tccaactcta tttcgtaagc ccctttatta tcggacaaca acgaatcgac atgataagca
    15481 tcccccacct caaaagccgg aatctcccgg gattctttac gcaatgactt ggtctcttcc
    15541 accggggcgg cagccatata gatatcccca tcttgtgta
//
