LOCUS       gnlProkkaPFMILDCK_508   3044 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PFMILDCK_508.
ACCESSION   gnlProkkaPFMILDCK_508
VERSION     gnlProkkaPFMILDCK_508
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 11:04:58
            Original ID  :: gnl|Prokka|PFMILDCK_508
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3044
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3044
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[1:2134]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2..2134
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..3044
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3044
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             2..2134
                     /NRPS_PKS="Domain: AMP-binding (41-302). E-value: 1e-64.
                     Score: 210.5. Matches aSDomain:
                     nrpspksdomains_ctg507_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (410-469). E-value: 2.3e-10.
                     Score: 32.8. Matches aSDomain:
                     nrpspksdomains_ctg507_1_PP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     207.3; E-value: 5.6e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg507_1"
                     /sec_met_domain="AMP-binding (E-value: 2.9e-77, bitscore:
                     247.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 8.1e-12, bitscore:
                     32.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMAENADMVLLLTDSSNEVGGIPSVRQLYLNGEQLSEPVVGDYTE
                     VLPDDCAYIIYTSGTTGNPKGVRISYRNLDTFTRNLIDKKLYHLSDPANRYLAFASISF
                     DASILELMMCIPAGGTLILAGEDERRDISLLDELIRREKVNIAFFPPSLLGMFADLDFP
                     SFKTLLFGAEAIGEKLFNRLKQQPYRLMNVYGPTENTVLSTIRIVGKDTSYDDIGYPLK
                     GTVCYVLSENLQQTTLGATGELCLGGPQVSLGYIGSVQLNEKSFISYDGERLYRTGDLV
                     QQQPDGSIRFIGRKDTQVKIRGFRIELTEIAERLNRDPDVERAHVVVVERNGRQLLGAY
                     LQPSVSGNFHPEEVKERLRAELPYYMIPNLWQVVDHFQRTINDKIDVRALPAFTSLELK
                     YVPPVHPGEVILCGILKEMLGLPQVSVEADLIDDLGLTSLDMLRLVTEANKKGCPINVS
                     AVYTARNLRRLLLVPRQEPIYWYRQQNLKKPVIILVCGSAYFNHLYFNLADRLYPKYDF
                     LVVDAIYDHFNKVATDIPELLEYYVRTVQPMIRERTVYALTGFCMGAELAVGLAEMLHR
                     SMGIMPKVFALDGQAWQNPALCQNYPLLVFPGDTDEMVRERNEIINIYFRTTPNLIYQG
                     EVIVLLSGLFHQQAGLSPEESWTEESYRIFRTEYDNCERLWNKYYPNAPVLRLPTDHWH
                     FLEGESLEQLITVFLK"
     aSDomain        125..907
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg507_1_AMP-binding.1"
                     /evalue="1.00E-64"
                     /label="ctg507_1_AMP-binding.1"
                     /locus_tag="ctg507_1"
                     /protein_end="302"
                     /protein_start="41"
                     /score="210.5"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DYTEVLPDDCAYIIYTSGTTGNPKGVRISYRNLDTFTRNLIDKKL
                     YHLSDPANRYLAFASISFDASILELMMCIPAGGTLILAGEDERRDISLLDELIRREKVN
                     IAFFPPSLLGMFADLDFPSFKTLLFGAEAIGEKLFNRLKQQPYRLMNVYGPTENTVLST
                     IRIVGKDTSYDDIGYPLKGTVCYVLSENLQQTTLGATGELCLGGPQVSLGYIGSVQLNE
                     KSFISYDGERLYRTGDLVQQQPDGSIRFIGRKDTQVKIR"
     aSModule        125..1408
                     /complete
                     /domains="nrpspksdomains_ctg507_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg507_1_PP-binding.1"
                     /locus_tags="ctg507_1"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       155..211
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg507_1_0001"
                     /evalue="1.20E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg507_1"
                     /protein_end="70"
                     /protein_start="51"
                     /score="27.0"
                     /tool="antismash"
                     /translation="AYIIYTSGTTGNPKGVRIS"
     CDS_motif       713..799
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg507_1_0002"
                     /evalue="1.00E-08"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg507_1"
                     /protein_end="266"
                     /protein_start="237"
                     /score="27.5"
                     /tool="antismash"
                     /translation="LGATGELCLGGPQVSLGYIGSVQLNEKSF"
     CDS_motif       872..934
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg507_1_0003"
                     /evalue="1.30E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg507_1"
                     /protein_end="311"
                     /protein_start="290"
                     /score="36.4"
                     /tool="antismash"
                     /translation="FIGRKDTQVKIRGFRIELTEI"
     aSDomain        1232..1408
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg507_1_PP-binding.1"
                     /evalue="2.30E-10"
                     /label="ctg507_1_PP-binding.1"
                     /locus_tag="ctg507_1"
                     /protein_end="469"
                     /protein_start="410"
                     /score="32.8"
                     /tool="antismash"
                     /translation="LCGILKEMLGLPQVSVEADLIDDLGLTSLDMLRLVTEANKKGCPI
                     NVSAVYTARNLRRL"
     CDS             2139..3032
                     /locus_tag="ctg507_2"
                     /transl_table=11
                     /translation="MQTENFTLGKKELLILLGLTLVLPFPINWALIELNPLTLMAGADD
                     VPTWIGFGGSYIGGIIGGIISIMILNKTLQQTGVLHHDLKLLQLDTIIYTQQQDWFTGF
                     KQELAENLKSIDLYVLNTVVSSISMKNYAYAKEVLTEINKGLEYQMVAASFSFTSTHLS
                     SEEKKYMNLVRRVQTEYSSFIKDILYYIPLAETISSRKKLNYDQLMDYTLSQYDYLQGQ
                     EGESTASGAIIPRVMEIDPSDDIRKELERIMEERLTGRTYLYHLKSDLAEATHQLIIYE
                     ENRINSILHKPEREMN"
ORIGIN
        1 gtatatggct gaaaatgcgg atatggtttt gttgttgacc gattcatcga atgaagtagg
       61 tggaattccg tccgtccgcc aactttacct gaatggggag caactatccg aaccggttgt
      121 tggtgactat actgaagttc ttcccgatga ttgcgcctat attatatata cttccggaac
      181 aacaggcaat cctaaaggtg tacgtattag ttatcggaat ctggatacat ttacgaggaa
      241 tctgatagat aagaaattgt atcatttgtc tgatccggca aacaggtacc tggcgtttgc
      301 gagtatcagt tttgatgctt ccatattaga actgatgatg tgtattccgg ccggaggaac
      361 attgatcctg gccggtgagg acgaacgcag agatatttct ttactagacg aactgattag
      421 gcgcgagaag gtgaatattg ctttttttcc tccttcgttg ctgggcatgt ttgccgacct
      481 tgactttcca tcctttaaga ctctgctctt tggtgcggag gctattggtg aaaagttatt
      541 taacaggctg aaacagcagc cttaccggtt gatgaatgta tatggaccga cagagaatac
      601 cgtactcagt accatacgga ttgtaggcaa agatacgtcg tatgacgata ttggctatcc
      661 gctcaaggga actgtctgtt atgttttgtc tgaaaacctc caacagacaa ctcttggggc
      721 tacaggagaa ctttgcttgg gaggacctca ggtttcgctg ggatatattg ggagtgttca
      781 gctgaatgaa aaatcattca tctcgtacga tggagaacgg ttgtacagga caggtgactt
      841 ggtacagcag caaccggacg gttcgatacg gtttatcggg cgaaaagata ctcaggtcaa
      901 gatacgtggt tttcgtatcg aattgactga aatagcagaa cgattgaata gagatccgga
      961 cgtggagaga gcccacgtag tagttgttga gcggaatggg cgtcaattat tgggagctta
     1021 tttgcaaccc tcagtctccg gtaactttca tccggaagag gtcaaagagc gtttgcgtgc
     1081 agaacttcct tactacatga tacccaattt atggcaggtg gtagatcatt ttcagcgtac
     1141 tataaatgat aagattgatg tccgggcgct cccggctttt acttcattgg agttgaagta
     1201 tgttcctcct gttcatccgg gggaggttat cttatgtgga attttgaagg aaatgttagg
     1261 tttgcctcaa gtcagtgttg aggccgattt gattgatgat ctgggattaa cttcgctgga
     1321 tatgttgagg cttgttaccg aggccaataa aaaaggatgt cccatcaacg tatctgcagt
     1381 ttatactgcc cgtaatctgc gccgattatt gctcgttccg cggcaagaac ctatctattg
     1441 gtacaggcag caaaacctga agaaacccgt aatcattctg gtttgtggat ctgcctattt
     1501 taatcatttg tactttaatt tggccgaccg cctttatccc aaatatgact ttctagttgt
     1561 agatgctatc tacgatcatt ttaataaagt ggccacggat attccggaac tgttggaata
     1621 ttatgtccgg acggttcagc caatgatccg ggagcgtacc gtctatgcgc ttaccggctt
     1681 ttgtatggga gctgaactgg ctgtcggcct ggccgaaatg ttacatcgct ccatggggat
     1741 aatgccaaaa gtttttgctc tggatggaca ggcttggcaa aatccggctc tctgtcaaaa
     1801 ttatcctttg ttggtatttc ccggagatac agatgaaatg gtacgtgaac ggaacgaaat
     1861 cataaatatt tattttcgaa ccactcctaa tctgatttat cagggagagg ttattgtttt
     1921 gctgtccgga ttgttccatc aacaggcggg attgtctcct gaagagtcgt ggacggagga
     1981 aagctatcgt atattccgga cagaatatga caattgcgaa agattatgga ataaatatta
     2041 tccgaacgct cctgttttgc gattgccgac agatcattgg cactttttag aaggggaatc
     2101 attggaacaa ttaataactg tgtttttgaa gtagatttat gcagactgaa aacttcactt
     2161 taggtaagaa agagcttctt attttgcttg gcttgactct tgtactgcct tttccaatca
     2221 attgggcatt aatcgaactg aatccgttga ctctgatggc gggtgcagac gatgtgccca
     2281 cctggattgg tttcggcggc agttatattg gaggaatcat cggagggatc atctcgatta
     2341 tgattctgaa caagacactt cagcagacag gtgtacttca tcacgatttg aaactcctgc
     2401 agttagatac cataatttat actcagcaac aagattggtt taccggtttc aaacaagaac
     2461 tggcagagaa tctcaaatct attgatttgt atgtgttgaa tacggttgtt tcgtctatat
     2521 ccatgaaaaa ctatgcatat gccaaagagg tgttgacaga aatcaataaa gggctcgaat
     2581 atcagatggt tgccgcatcc ttttctttca cttctacgca tttatcatcc gaagaaaaaa
     2641 agtatatgaa tctggtacgc cgcgtacaga ctgaatatag ctcttttatc aaggatattc
     2701 tttactatat tcctttggca gaaacgatat cttccaggaa aaaactaaac tatgatcagc
     2761 tgatggacta tactttgtcc caatatgatt atttgcaagg tcaggaaggg gagtctacag
     2821 cttcgggagc catcataccg cgtgttatgg aaatcgatcc atctgatgat atacggaaag
     2881 aactagaacg gataatggaa gaaagattaa ccgggcgtac ctatttgtat cacctgaagt
     2941 cagatcttgc agaggctacg catcaattaa ttatttatga agagaaccgt ataaactcta
     3001 ttctgcataa acctgagaga gaaatgaatt gacatatatt aata
//
