LOCUS       c00055_gnlPro..        14701 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BNNNKGJG_55.
ACCESSION   c00055_gnlPro..
VERSION     c00055_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 12:58:33
            Original ID  :: gnl|Prokka|BNNNKGJG_55
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1373
            Orig. end    :: 16074
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14701
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[11373:16012]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14639
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..14701
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14701
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             507..1511
                     /locus_tag="ctg55_3"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTRDMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCKNPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYDENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHT
                     YTEPDEVVDFVTKTGCDSLAISIGTSHGAYKFTPEQCHIDPKTGRMVPPPLAFDVLDGV
                     MKELPGFPIVLHGSSSVPEEEVATINQFGGALKAAIGIPEEELRKAAKSAVCKINIDSD
                     SRLAMTAAIRKVFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSDNKLAE"
     CDS             complement(1606..3201)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg55_4"
                     /sec_met_domain="MFS_1 (E-value: 1.8e-14, bitscore: 43.2,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKLNLPTRPWVPQWLGIVTMFIVIFPITLLNGAYTGSMVEVSNT
                     LGVLSEDITMAYYSASVGMAVAYPIVPKIRTIATPKTLLLTDLLLQIFFSLVCAKTGSM
                     DVIMVCSFCMGFLKAFVMLEFIILIRPLFSPKNVRSEFYAYFYPIVFSGGQLSMAITAQ
                     LAYHYQWQHMYYFVTILLLIALLFVICFFRYARRPMHIPFKEMDGRSMFIIATAFLLTL
                     YTFTYGKTLDWFASPKIRVYVFVIPLLIVLFIHRQRTQGKPFVSLKPLFLHKSIIGYGF
                     MVLAMFLTATSSLVTNYMNSIIRVDSIHANSLSLWLLPGYVVGAVICFWWFRWQRWRFR
                     FLISGGMFCYVIYLAILYFGITPYGTYEMLYLPILFRGVGMMVIFIAFGVFVVEDLDPR
                     LTLSNAFFLISFRSVLAPVLSASFFNNMLYYLQAKGMNILSENMTLTNPLAEQKYNQAL
                     SNALAQGHEFSEAGQLAANSLYSTLQQQSLLLALKTLIGYVLILALVIAVIAAFIPFHK
                     TLKVAVVKTGDDMV"
     CDS             complement(3206..4273)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg55_5"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 5e-12, bitscore:
                     35.5, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTHQIKLKQLRRLKFRNIFLNTVCILLALAGISWTVNYFWKYAR
                     YEITNDAVVDQYIAPLNIRIPGYIKEVRFTEHQYVHAGDTLLILDDQEYRIRLKDAEAA
                     LMDALGSKEVLNSGIRTSGVNVAVQEANIAETLARLSQQEAELNRYTRLLKKQAVSQQD
                     YELAKANFEATRARYNALLRQKEAAQSQYSETSKRSTGAEANILRKEADLEMARLNLSY
                     TVVTAPYDGYTGRRTLEPGQFVQGGQTLSYLVRGNDKWVTANYKETQIAHIYIGQKVRI
                     KVDAFSGRTFHGTVTAISEATGSKYSLVPTDNSAGNFVKVQQRIPVRIDLNDASPEEME
                     CLRAGMMVETEAVRP"
     CDS             complement(4286..4726)
                     /locus_tag="ctg55_6"
                     /transl_table=11
                     /translation="MTNNESERELVLQTLRTWMAFRQAVQRVLKRHNVDMTFEMLQVMN
                     CLWNKQGISQQSLAEKTAKDKACLTNLINNLEKKNWVIRKEGPSDRRNRLIFLTPQGEE
                     LALTVKPLINDIYAQTGAEMEASRITECIEDLKRLHEVLNEI"
     CDS             complement(4884..6734)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg55_7"
                     /sec_met_domain="Alpha-amylase (E-value: 7.6e-64, bitscore:
                     206.2, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLLLLLGSFLLSLTTYAAMNISKIDPPFWFTGMNNPELQLMVY
                     GEGIGQASVSVNYPGVSLSSVVKLESNNYLLVYLHLDKEVKPGKMPITFTVGKKKLVKE
                     YELKARSKAGVDHKGFDASDALYLLMPDRFANGNPDNDRIEGMAEYKVDRNDPNARHGG
                     DLAGIEQNLDYFTDLGVTALWFTPVLENNMKGGSYHGYATTDYYKVDPRFGTNEEYRSL
                     IAKAHNRGIKVVMDMIFNHCGVEHPWIKDMPSKDWFNHADFKNNFVQTSYKLTPHVDPY
                     ASEYDFDQMNNGWFVEAMPDLNQKNPHVYKYLLQNSLWWIEYADIDGIRMDTYPYADYD
                     AMSNWMKELNEEYPNYNTVGETWVTEPAYTAWWQKDSKLSAPRNSHLKTVMDFSFFDKV
                     NTAKNEQTDTWFKGLDRVYNNFVYDYLYPNPASVLAFIENHDTDRFLGEGENLDMLKQA
                     STLLLTTRRIPQLYYGTEVMMNGVKSKSDGYVRKDFPGGWADDKENALTPEGRTRLQNE
                     SYNFYRNLLNWRKGNDVIAKGSMKQFMVQHGVYAYARQYKGKTVFVLLNGTDKEVKLPL
                     KYYAEVLKDKTQGKDVISGKVTALNEELTMAPRQSMVIEL"
     CDS             complement(7216..8508)
                     /locus_tag="ctg55_8"
                     /transl_table=11
                     /translation="MKHWILLLYLGFSVMLRAQNTASVQEAMANYDYKTVIRLIDEESA
                     SPQLLIQKAKALKGLGRTAEALSTLQHIIIELPENQQALVEAAECCRQLSKFNEALGYY
                     RKVMELNPEHIYAHLQYTRLLYNYQRYGDALRESIALARKDSSATVLRLMAESMEGAGM
                     PVESMFCYLSIIRKYPSDYLSVAKLGSIFNTMKDYEGAIALTEAYRRTDSTNVEVNRQN
                     ALAYCLRKEYPTAIKRYQDLTARGDSTLLTCYYLGVSYYATKEYYKARDWLLKAKSCQS
                     PGANLLYYLGRSCSKTLWKQEGIGYLNQAIALTIPADSIMERLYSGLADCYRQTKQTRD
                     QIKATKEQYKYAPDKHILLYNLAFLSDKIGDTKATEHYLQAFLRTKSKQNAVLQQPDDD
                     EEEPAPYIDYYKSATNKLESIRKEKFLKGEK"
     CDS             complement(8521..9852)
                     /locus_tag="ctg55_9"
                     /transl_table=11
                     /translation="MRTRTMKPLFLIFCLCLSPLLMGQNQNKIQEAMANYDYETAVELI
                     NKEPPTIPLLMQKAKALKGIGSNAEALRSIRQVIAEDSTNQQAHIEAAECCKAMAKYND
                     ALDYYRKAISLNPKNKYARLQFINLLCNTKNYAEAFGESSMMSETDSSAVVLHLQAQSL
                     EGMQQILPAIGCYEVIQDKYPDDYLAAAKLGNLNIVAGYPEYAIQATERYRERDSTNLI
                     VNQQNALAYCHAEQYPTAIKRYEKLCQQGDSSTQTLYYLGVSYYADEYYYEAHACFSKL
                     QKEMEENPNLLYYLGRCCAKTSWKKEGIEHLEKAIELTIPKDSTMIRLYKGLVDCCKLA
                     QDTPKQIQALRELYKYDKTNHKLLYDIAWNYSYQLKDNKSAERYLQAFLKTRKANARKE
                     EPVSEKGELVLGLENYYNAAENWLKDLQKEKFFKEGIPLESQKQ"
     CDS             complement(10001..11161)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg55_10"
                     /sec_met_domain="OAD_beta (E-value: 5.5e-154, bitscore:
                     502.1, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFVSFLGNNLVDFWGYTGFANATPGHLFMLLIGLFFIYLAVAK
                     EFEPMLLIPIGFGILIGNIPFNMEAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYIIALLIGFEPNQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRALTTKHERLIRMKPPRIVSHTEKVIFP
                     IVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDVITILLGLTVGAS
                     TQASQFLTWDSILIFILGAFSFIIATASGVMFVKFFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVIGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             complement(11164..11595)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 69.7; E-value:
                     4.8e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg55_11"
                     /sec_met_domain="Biotin_lipoyl (E-value: 1.1e-22, bitscore:
                     69.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQYKYKINGNLYNVTVNDVEDNIANVEVNGTSYKVELDKPVKAA
                     PKPVTRPAAAPKTETGASVVTKQPTASKKDGVKSPLPGVILDIKVKEGDTVKRGQTIII
                     LEAMKMENNINANKDGKVAEIKVNKGDSVLEGTDLVIIE"
     CDS             complement(11621..12535)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg55_12"
                     /sec_met_domain="OAD_gamma (E-value: 1.8e-16, bitscore:
                     50.6, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKRIGIFIALLAMVCMGLRAQSATSLRINEVLVVNDQNYQDDY
                     GLHNAWIEIFNTSFASVNLEGCFLTNDKNNPTKYPIPKGDVLTLIKPRQHALFWADGMP
                     NRGTFHVNFTLDPNKENYIALYDSNGKTLIDEVTIPAGQLADRSYAREKDGSANWVVKG
                     EGEHSYVTPSTNNMTIDKNPKIENFKKHDSIGIGMAIIAMSVVFIGLVLLYLSFKAVGN
                     VAVRLGKKNAMKATGITDKTEAKEKNLGSHTGEETAAIAMALHEYLNDAHDVEDMILTI
                     NKVKRTYSPWSSKIYTLRQTPKR"
     CDS             complement(12556..14109)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg55_13"
                     /sec_met_domain="CT_Btheta (E-value: 2.8e-291, bitscore:
                     955.9, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIELRAQARLGGGEKAIEKQHAKGKYTARERIAQL
                     LDEGSFEELDMFVQHRCTNFGQEKKHFLGDGVVTGYGTIEGRLVYVFAQDFTVFGGSLS
                     ETMAQKICKVMDMAMKMGAPVIGINDSGGARIQEGINALSGYAEIFQRNIMASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMTEGTSYMFLTGPAVVKTVTGEDVSQEDLGGASVHAS
                     KSGVTHFTAETGEEGLAIIRKLLSFIPQNNLEEAPLVNCTDPIDRMDDLLNEIIPDSPN
                     KPYDMYEVIGAIIDNGEFLEVQKDYAKNLIIGFARMNGQSVGVVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTV
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVAVLYAKEAKDQENPAQFLA
                     DKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLTNPAKKHGNIPL
                     "
     CDS             complement(14235..14639)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg55_14"
                     /sec_met_domain="Glyoxalase_4 (E-value: 3e-24, bitscore:
                     75.4, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGDTKIELLEPTCPESTIAKFIENKGAGVHHVAFAIEDGVANALAEAESKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
ORIGIN
        1 ccgtactggg ggcaaagaaa cacgtcgagg atatgactga agatgacctt tacaacccct
       61 ggtgggtgac gctggaagat aagggagtgg gcactttgct ctatcgaggc aaatggaatc
      121 tgttcgatca gatcatcctt tcacccacgc tgcttcaagc aacaaaagga ttgaaatatg
      181 atcacaatga agttttcatg cgtgattacc tgtttcagca ggatggtaaa tataagggtg
      241 cacccctgcg tacatatggt ggcagagtgt ggttggatgg ttacagcgat catttgccta
      301 ccattatata tatgaggaaa caataaaaaa cctttatttg ctacgtagac attacaaaca
      361 gctcttaaag gatgggaaat aatttgaaat agaattgaat tacgctcctc aaacggatat
      421 ttccgcccga gggtttctct attcaaagga ttattcttac ttttgcatag aatttttaat
      481 tcactaacaa taaactttta aacaaaatgg ttaattacaa agatttaggt ctggtaaaca
      541 ctagagatat gtttgctaag gctatcaagg gtggatatgc aatccctgca ttcaacttca
      601 acaatatgga acagatgcag gctatcatca aggctgctgt agaaactaag tctccggtta
      661 ttttgcaggt atcaaaaggt gctcgtcagt atgctaacgc tacattgttg cgttacatgg
      721 ctcagggtgc tgtagaatat gcaaaagaac tcggctgcaa aaatcctgaa atcgttttgc
      781 acctcgacca cggagatact ttcgaaactt gcaaaagctg tatcgactca ggcttctctt
      841 ctgtaatgat cgacggttct caccttcctt acgacgaaaa cgttgctctg actaagaaag
      901 ttgttgaata cgctcaccag ttcgatgtaa ctgtagaagg tgaacttggc gtattggcag
      961 gtgtagaaga cgaagtttct tctgaccacc acacatatac tgaaccggac gaagtagttg
     1021 atttcgttac caagacaggt tgcgattcat tggctatctc tatcggtact tctcacggtg
     1081 cttacaaatt tactccggaa cagtgccaca tcgatccgaa gacaggccgt atggttcctc
     1141 ctccgttggc attcgacgta ttggacggtg taatgaaaga acttccggga ttccctatcg
     1201 ttcttcacgg atcatcttca gttcctgaag aagaggttgc aactatcaac cagtttggtg
     1261 gtgcactgaa agctgctatt ggtattcctg aagaggaact gcgtaaagcc gctaagtctg
     1321 ctgtttgcaa aatcaacatc gactcagact ctcgcctggc tatgactgct gctatccgta
     1381 aggtattcgc agaaaaaccg gctgagttcg acccgcgtaa atatctggga ccggctcgcg
     1441 acaatatgga aaaactctac aagcacaaaa ttatcaacgt gctgggttct gacaacaagt
     1501 tagctgaata aattccaaat ctagtattta aaagttttac ttgatttaat ttatatttta
     1561 agaagccact caagcaattg agtggctttt ttgtatccct tctcattata ccatatcgtc
     1621 acccgtcttc acaacagcca ccttcagcgt tttatggaaa ggaatgaacg ctgcgatgac
     1681 agcaatcacc agtgccagta tcagtacata gccgattagg gttttcaggg caagcagcag
     1741 ggattgctgc tgcaaagtgg agtacagact gttggctgcc aattgtccgg cctcgctgaa
     1801 ttcgtgccct tgcgccaggg cattgctcaa tgcctgattg tatttttgtt cggccagcgg
     1861 attggtcagc gtcatgtttt ccgaaagaat gttcatcccc tttgcctgca gatagtaaag
     1921 catgttgtta aagaacgaag cggacaggac cggagccaat actgagcgga atgaaatcag
     1981 gaagaaggca ttggacaacg tcaggcgcgg gtctaaatct tcgacaacaa acacaccgaa
     2041 cgcaatgaat atgaccatca tccccactcc ccggaacagg atggggaggt agagcatttc
     2101 ataagttcca taaggggtga taccaaagta gaggatagcc agatagatga cgtagcagaa
     2161 catacctcct gaaatgagga agcgaaaccg ccatcgttgc catcggaacc accagaagca
     2221 aatgacggct cctaccacat atccgggcaa tagccacagg ctcagcgaat tggcgtgtat
     2281 gctgtctacc cggatgatgc tgttcatata gttggttacc agtgaactgg tggctgtcag
     2341 gaacatggcg agtaccatga agccatatcc gatgatggat ttatgcagaa agagtggttt
     2401 caggctgaca aagggtttgc cttgtgtacg ctgccgatgg atgaagagaa ctatcaggag
     2461 cgggatgacg aatacatata ctctgatctt cggggatgcg aaccaatcga gtgttttccc
     2521 gtaggtaaat gtatagagcg ttagcaggaa agcggtggcg atgatgaaca tgcttcttcc
     2581 gtccatttct ttgaacggaa tgtgcatggg acgccttgca tagcggaaga aacagatgac
     2641 gaacagaagg gcgatcagca agaggatggt gacaaaatag tacatgtgct gccattggta
     2701 gtgataggcc agttgagcgg tgatagccat cgatagctga cctccggaga aaacgatggg
     2761 gtagaagtag gcatagaatt cacttcgtac gtttttcgga ctgaagagcg ggcggatcag
     2821 gatgatgaac tccaacatga cgaaggcttt gagaaatccc atacagaaac tgcataccat
     2881 gatgacgtcc atactaccgg ttttggcgca taccaggctg aagaatatct gtagcagcag
     2941 gtcagtgagc agtaaggttt tcggagtggc tatggtgcgt attttcggta cgatgggata
     3001 ggcaacagcc atccctaccg aagctgaata gtaagccatg gtaatatctt cgctcaatac
     3061 tcccagcgtg ttcgatactt cgaccatact tcctgtgtag gcaccgttga gcagggtgat
     3121 gggaaagatg acaataaaca tggtcacgat gcccaaccat tgaggcaccc agggacgggt
     3181 aggcagattg agcttcacca taagcctaag ggcggaccgc ttccgtttct accatcatcc
     3241 ctgcacggag gcattccatc tcttcgggtg aggcgtcatt gagatcgatg cggaccggaa
     3301 tgcgttgctg cactttgacg aagttccctg ccgaattgtc ggtcggtacc agggagtatt
     3361 tcgatccggt ggcttcggaa atggcggtta cggtcccgtg aaaagtgcgt ccgctgaaag
     3421 catctacttt gatgcggact ttttgcccga tatagatatg ggcaatttga gtctctttat
     3481 aattggctgt cacccacttg tcattgcccc gtaccaggta ggaaagagtt tgtccgcctt
     3541 gtacgaactg tcccggttca agtgtacgtc gtcccgtgta tccgtcatag ggtgcggtga
     3601 caacggtata cgacaggttt agtctggcca tctccaggtc ggcctccttc cggaggatat
     3661 tggcttcggc gcctgtactg cgtttgctgg tttcggaata ctgtgattgg gccgcttctt
     3721 tttgtcgcaa cagggcgttg tatcttgccc gggtcgcttc gaagttcgct ttggccagtt
     3781 cataatcctg ttggctgacg gcctgctttt tcaggagccg ggtatatcgg ttcagttccg
     3841 cttcttgctg tgaaaggcgt gccagtgttt cggctatgtt ggcttcttgt acggctacat
     3901 ttactcctga agtccggatg ccggagttta acacttcctt tgatcccaag gcatccatca
     3961 aggccgcttc cgcgtctttc agccggatcc ggtattcctg gtcgtccagt atcagtaacg
     4021 tgtcgccggc atgaacatac tggtgttcgg taaaacgtac ttctttgata tagcccggta
     4081 tccggatgtt tagcggagcg atgtattgat ccactacggc atcattggtt atctcgtagc
     4141 gggcgtattt ccagaagtag tttactgtcc atgaaatacc tgccaatgcc agcaggatgc
     4201 atactgtgtt gagaaagatg ttcctgaact tcagtcttct caattgtttt agctttatct
     4261 gatgggtgga catggcggat ttcttttaga tctcattgag cacttcatgc agtctcttca
     4321 ggtcttcgat gcattccgtt atccggcttg cctccatctc tgctccggtt tgggcataga
     4381 tatcgttgat caggggtttc acggtgaggg caagttcttc gccttggggt gtcaggaaaa
     4441 tcaggcggtt tcggcggtcg gaggggcctt ccttccgtat cacccagttt ttcttttcca
     4501 gattattaat cagattggtc aggcaagcct tgtcctttgc tgttttctca gccagggatt
     4561 gctggctgat gccttgtttg ttccacaggc agttcattac ttgcagcatc tcgaaggtca
     4621 tatccacgtt gtggcgtttg agcacccgct gaacggcctg gcggaatgcc atccaggttc
     4681 gtaaggtttg taggacgagc tcgcgctccg attcgttgtt tgtcatcgtc gtattctttt
     4741 agtcggtgca aaggtaggaa tattcttcga taatagtcaa acgtttgact attattattc
     4801 gcattaggct acacaaaggg cacagaggat gtcgggtgaa atcctttgtg ccctttgctt
     4861 atgcggttat aaccggtgtg agattaaagc tctataacca tcgattggcg gggtgccatt
     4921 gtcagttctt cattgagtgc cgttactttt ccgctaatga cgtcttttcc ttgagtcttg
     4981 tctttcagca cttcggcata gtatttcagg ggaagtttca cctctttatc cgtaccgttc
     5041 aacaggacga agaccgtttt ccctttatat tggcgtgcat aagcatatac gccgtgctgc
     5101 accatgaact gtttcatgct gcctttggcg atcacatcgt tgcccttacg ccagttcagc
     5161 aggttgcggt agaagttata gctttcattc tgcaatcgag tacgtccctc gggagtcagg
     5221 gcattctctt tatcgtccgc ccatccgccc gggaagtcct ttcgtacata gccgtcgctt
     5281 ttactcttta ctccgttcat catcacctcc gttccataat agagttgcgg gatgcgtcgg
     5341 gtggtcaata aaagggtgga ggcctgtttc agcatatcga ggttttcgcc ttcacccagg
     5401 aaacggtcgg tgtcatgatt ctcgatgaaa gccagtacgg aagccggatt gggatacaga
     5461 taatcgtata caaaattgtt gtagacacgg tccaatcctt tgaaccaagt gtccgtttgt
     5521 tcattcttgg ccgtgttgac tttgtcgaag aagctgaaat ccatgactgt tttcaagtga
     5581 ctgttgcgcg gggcggagag cttggagtct ttctgccacc aggctgtata ggccggttcg
     5641 gtaacccagg tttcgcccac cgtgttgtag ttggggtatt cttcgttcag ttctttcatc
     5701 cagttgctca tggcatcgta atcggcatac gggtaggtgt ccatccggat gccgtcgata
     5761 tcggcgtact caatccacca caggctgttc tgcaagaggt atttgtatac gtgagggttc
     5821 ttttggttga ggtcaggcat ggcttccacg aaccagccgt tgttcatctg gtcgaaatcg
     5881 tactcagagg catacggatc tacatgtgga gtcagcttgt aggaagtttg cacaaagttg
     5941 ttcttgaagt ccgcatggtt gaaccagtcc tttgaaggca tgtccttgat ccagggatgt
     6001 tctactccgc aatgattgaa gatcatgtcc atcacgacct taatgccccg gttgtgggct
     6061 ttcgctatca gtgagcgata ttcctcgtta gtgccgaaac gtgggtctac cttgtaataa
     6121 tcggttgttg catatccgtg atatgagccg cctttcatat tattttcgag taccggggtg
     6181 aaccagagtg cagtgactcc caaatcggta aaatagtcta gattttgttc gataccggcc
     6241 aggtcgcctc cgtgacgtgc gttcgggtcg ttgcggtcca ctttatattc ggccatgcct
     6301 tctatccggt cgttatccgg attgccattg gcaaaacggt ccggcatcag caggtataat
     6361 gcatccgatg cgtcaaaacc tttgtgatcg actccggctt tgctgcgtgc tttcaattcg
     6421 tactctttca ccaatttctt ctttccgacc gtaaatgtga tgggcatctt gcccggcttt
     6481 acttctttat cgagatgcag gtagacaagc aggtaattgt tgctttccag tttcacgacg
     6541 ctgctgagcg atacaccggg ataatttact gatacggatg cctggccgat gccttcaccg
     6601 tataccatta attggagttc cggattgttc ataccggtga accagaaggg cggatcgatt
     6661 ttggatatgt tcatggctgc ataagtggtt aatgacagta ggaatgaacc taagagtaac
     6721 aataattttt tcatgatatt agctcgttat tatttaatgt tgctaatata gggtaaatca
     6781 tcggattgtt ttccgttttc tttcttactg tgtgccatct atttatgcaa acgttttcat
     6841 tggagaattc tccgggatgg agctcaaccg ataaggaaca cttttcgatg caatcaggtg
     6901 aacgtgatgt ccggaaaagg agatgccgtc atagcttcgg ctacgcagca ccgtaacttc
     6961 ggctacgcag caccgtaact ttatctacgc agcaccgtaa cttcggctac gcagcaccgt
     7021 aactttggct acgcagcacc gtaactttag ctacacagca ccgtaatttc ggctgcgtgc
     7081 cgatgtgact tcggttacgt gccactgtgc cttctaccgc acatcttcaa atttattttc
     7141 cattattctc cctctgtgaa actctgtctg cactcagtgg tgaattgtcc gaaacgatgc
     7201 atctatccga tcaattcact tttctccctt taagaatttc tcttttcgga tgctttccaa
     7261 tttattggtg gcacttttgt agtaatctat gtagggtgcg ggttcttctt cgtcatcatc
     7321 cggctgctgt agtactgcat tttgtttgga ttttgttcgc agaaaagcct gcaagtaatg
     7381 ctctgtggct ttagtatctc ctattttgtc cgataagaac gccaagttat aaagtaaaat
     7441 atgcttgtca ggggcatatt tgtattgttc tttggtagcc ttgatttggt cccgggtttg
     7501 cttggtttgc ctgtagcagt ctgccaagcc tgagtataag cgctccatga tactgtcggc
     7561 ggggatagtc agggcgatag cctggttcag atatcctatt ccctcttgtt tccataatgt
     7621 cttggagcac gaacgtccca aatagtagag taggttggcg ccgggtgact ggcatgattt
     7681 tgctttgagt agccaatcgc gcgctttata gtattctttc gtagcgtagt agctgactcc
     7741 caggtaataa catgtcagca gtgtgctgtc tccccgggcg gtcagatcct gataacgttt
     7801 gatggcggtg ggatattctt tgcgcagaca atacgccagt gcgttttgac ggttcacttc
     7861 tacattggtg ctgtccgtcc ggcggtatgc ttctgtcagg gcaattgccc cttcgtaatc
     7921 tttcattgta ttgaagatac tgcccagctt agctaccgag agatagtcgg agggatattt
     7981 cctgatgatg gaaagatagc aaaacatact ttctaccggc atgccggctc cttccatgct
     8041 ttccgccatc agtcgcaata cggtggcgga actgtctttc ctggccaatg cgatactctc
     8101 acgcaatgca tcgccgtatc gctgatagtt gtataacaag cgggtgtatt gcaagtgtgc
     8161 gtaaatatgt tcgggattga gttccatcac cttccgataa taccccaagg cctcgttaaa
     8221 tttgctcaat tgcctgcaac attctgctgc ctctaccaat gcctgctgat tttcgggcag
     8281 ctcgataatg atatgttgca aagtggacag ggcttcggcg gtacgcccta aaccttttaa
     8341 agctttggct ttctgtatga gtaactgtgg tgatgcactt tcttcatcaa tcagtctgat
     8401 caccgtttta tagtcatagt ttgccattgc ttcttgaacg gaggcggtgt tctgggctcg
     8461 cagcattacg ctgaagccca gatagaggag gagtatccaa tgtttcatgg gggatagatt
     8521 ctattgtttc tgactttcta acggtattcc ttctttgaag aacttttctt tctgtaagtc
     8581 tttcagccaa ttttcggcag cgttgtaata attttcaagt ccgagtacaa gttccccttt
     8641 ctcactcacc ggttcttctt tcctggcatt cgcctttcgg gtttttaaga aagcctgcag
     8701 ataacgttcg gccgatttgt tgtctttgag ttgatatgaa tagttccagg cgatgtcata
     8761 aagaagttta tggttcgtct tgtcatattt gtacagttct ctgagagcct ggatttgctt
     8821 tggagtatcc tgagccagtt tacaacaatc caccaagcct ttgtaaagtc ggatcatggt
     8881 gctgtctttg ggaatggtca gttcgatagc tttctccagg tgttcgatgc cttctttttt
     8941 ccaggaagtc ttggcgcagc aacgtcccag ataatagagc agattgggat tttcttccat
     9001 ctctttttgc agtttgctga aacacgcgtg cgcttcgtaa taatattcat ctgcgtaata
     9061 gctgactccc aggtagtata aggtctgtgt actgctgtcc ccctgttggc acagcttttc
     9121 atagcgcttg atggctgtcg gatattgttc ggcgtggcag taggcgagag cgttttgctg
     9181 gttgacaatc aggttggtgg agtcccgttc cctatagcgt tcggtagctt ggatggcata
     9241 ttcgggatat ccagccacaa tgttcaggtt tccgagtttg gccgcagcca gataatcgtc
     9301 cggatattta tcctgaatga cttcatagca accgatagcc ggtagtatct gttgcatccc
     9361 ttcaaggctt tgagcctgta ggtggagcac tacggccgaa ctgtccgttt cggacatcat
     9421 tgaactttct ccaaaagcct cagcatagtt tttggtgttg caaagcaggt tgatgaattg
     9481 caaacgggca tacttgtttt tgggattcag gctgatggct ttccggtagt agtccagcgc
     9541 atcgttgtac ttggccattg ctttacagca ttccgctgct tcgatgtgtg cctgttggtt
     9601 ggtggagtct tccgctatca cttggcggat ggagcgtaga gcttccgcat tgctgccgat
     9661 tcctttcagg gcttttgctt tctgcattaa cagtgggatg gtgggaggtt ccttgtttat
     9721 cagttcaacg gcagtctcgt agtcatagtt tgccattgct tcctgaattt tgttttgatt
     9781 ctggcccatc agtaggggac tgaggcaaag acagaaaata aggaagagtg gtttcattgt
     9841 tcttgttctc ataggacgta ttgttttatt gtccgcaagt tagtaaaaat atccattcta
     9901 cgaaaggctc gtaatgtctt ttagatagat taacgcaaaa aaaagacgcc cttctttgcg
     9961 aaaagaagga cgtctacctt actaatgaaa aaaatatcgt ttacatgagg aatccgagca
    10021 ggataccggc agctacagcc gaaccgataa cccccgctac gttaggaccc atggcgtgca
    10081 tcagcagata gttggtcgga tcatattcca aaccgattac ctgtgaaata cgtgccgagt
    10141 cgggtacggc ggatacacct gcattaccaa tcagcggatt gatcttattg cctttcttca
    10201 agaatagatt gaagaatttg acaaacatga cacctgacgc tgttgcgatg atgaaagaga
    10261 atgcaccgag gataaagatc aagatagaat cccaggtgag gaattgtgaa gcttgggtag
    10321 aagctcccac agtcagtccc aacaggatag tgatcacatc gatcaacgga ccactggccg
    10381 tatttgccaa acgacgggtt actccacttt ctttcagaag attaccgaag aacagcatac
    10441 ccagcaaagg cagacccgaa ggaaccagga agcatgtaag caacagaccc acgatgggga
    10501 agattacttt ttccgtatgc gatactattc tcggtggttt catgcggatc agacgctcgt
    10561 gtttggtggt tagcgcacgc atgataggtg gctgtatcac cggcaccagc gccatgtaag
    10621 aataggctga cacagcgatg gcacccatca ggttgggagc cagtttggac gaaaggaaga
    10681 tggccgtcgg tccgtcggca ccgccaatga taccgatagc acccgcctgg ttgggttcga
    10741 atccaatgag cagggcaatg atatacgcgc cgaagatacc gaattgcgcg gcagctccga
    10801 tcagcatcaa tttggggttg gagatcagcg ccgagaagtc cgtcatggct ccgataccca
    10861 ggaaaatgag cggcggatac cagccggagg ttactccttg ataaaggatg ttcagtaccg
    10921 aaccttcttc gtaaataccc acttttaatc cggcttccat attgaatgga atattaccga
    10981 tcagaatacc gaagccaatg gggatcagca gcatcggttc aaattctttg gctacggcaa
    11041 ggtagataaa gaagagaccg attagcaaca tgaaaagatg tccgggtgtc gcgttcgcaa
    11101 aaccggtgta tccccagaag tcaacaaggt tattccctaa gaatgatacg aaatctccca
    11161 taattattca atgattacga ggtctgtacc ttcaagtaca gaatctcctt tattaacttt
    11221 aatttctgct acttttccgt ctttattggc attgatgttg ttttccatct tcatagcctc
    11281 aaggatgatg atcgtctggc ctctcttcac ggtatcccct tctttcactt ttatgtcgag
    11341 gataacgccc ggaagcggag atttcacacc gtcttttttg gaagctgtcg gttgtttggt
    11401 tactaccgaa gcacctgttt ccgttttcgg agcggctgcc ggacgggtca ccggtttcgg
    11461 agcggctttg acgggcttgt ccaactctac tttataagag gttccgttca cttcaacgtt
    11521 ggctatgtta tcttctacat cgttcactgt aacgttgtaa aggttgccgt tgattttata
    11581 tttatattgt ttcattgctt cattttatta gggttagtaa ttatcttttc ggagtctgac
    11641 gcagtgtgta gatcttcgaa ctccagggtg agtaggtgcg tttcactttg ttgatggtca
    11701 aaatcatgtc ttcaacgtcg tgagcgtcat tcaggtattc atgcaaagcc atggcgattg
    11761 cggcggtttc ttcacctgtg tggctaccca ggttcttttc cttcgcttcc gtcttgtcgg
    11821 tgataccggt ggctttcatc gcgtttttct tacccagtct gaccgctacg ttacctaccg
    11881 ccttgaatga aagatacaag agtaccaaac ctatgaatac gaccgacatg gcgatgatgg
    11941 ccataccgat accgatagag tcgtgtttct tgaagttctc gatcttcggg tttttgtcga
    12001 tagtcatatt gttggtgctc ggagtgacat agctgtgttc tccttcacct tttactaccc
    12061 agttggcact tccgtctttt tcgcgagcgt atgaacggtc ggcaagctga ccggcgggta
    12121 tggttacttc gtcaatcaga gttttaccgt tagagtcata caaagcaatg taattctctt
    12181 tgttcgggtc gagcgtaaag ttcacgtgga acgtaccccg gttaggcatt ccgtctgccc
    12241 agaacaaagc atgttggcgc ggcttgatca gagtcagcac gtcgcctttg ggaataggat
    12301 atttggtcgg attgttttta tcgttcgtca gaaagcaacc ttccagattt acagaagcga
    12361 aagaggtgtt gaatatctct atccacgcat tgtgcagtcc gtagtcatcc tgatagttct
    12421 ggtcgttgac gaccaaaacc tcattgattc tcagactggt ggcactttgc gccctgagcc
    12481 ccatgcaaac cattgccagc agagcgataa atatcccgat tcttttctta ttcataacaa
    12541 tcgatgttta atttgttaca atggaatatt accgtgcttt ttagcagggt tggttaattt
    12601 tttggtctgc agctgttgca gggcgcggat cacgcggaaa cgagtgtttc tcggttcgat
    12661 aacatcgtca atgtaaccgt atttggctgc attgtatggg ttggcgaaca gtttagtgta
    12721 ctcggcttcc ttgtctgcca ggaattgagc agggttttcc tgatctttgg cttctttggc
    12781 atacaatacc gctactgcac cggcaccgcc cattacggcg atttcggctg tcggccatgc
    12841 atagttcatg tcgccgcgga gttgcttgca actcattacg atgtgcgaac caccgtaaga
    12901 tttacgcagg gtaacagtta ctttgggcac agtggcttca ccataagcgt acagcaactt
    12961 ggctccgtgc aggattacac cattatattc ctgacccgta cctggaagga atcccggaac
    13021 gtctaccaat gtcaccagcg gaatgttgaa tgcgtcgcag aagcgaacga agcgtgcacc
    13081 tttgcgtgaa gcattgctat cgagtactcc ggcgaggtat ttaggctgat tggcaaccac
    13141 acctaccgat tgtccgttca tacgggcaaa accgataata agatttttcg catagtcttt
    13201 ctgtacttcc aggaattctc cgttatcgat gatggcgccg atcacttcgt acatatcgta
    13261 cggtttgttc gggctgtcgg ggatgatctc gttcagcagg tcgtccatac ggtcgatggg
    13321 gtcggtacag ttcaccaatg gagcttcttc caggttgttt tgcggaataa agctgagaag
    13381 cttgcgaata atcgccagac cttcttcacc ggtttcggca gtgaagtgag ttacaccgga
    13441 cttgctggca tgtacgcttg caccacccag atcttcctga gacacgtctt cacccgttac
    13501 tgttttcaca acagccggtc cggtgaggaa catgtaagat gtaccttccg tcatcagcgt
    13561 gaagtccgtc agggcgggag agtaaaccgc accgccggca cacggaccga aaatacctga
    13621 aatctgtggg atgacacccg aagccatgat gttgcgctgg aagatttcag cataaccgga
    13681 cagggcgttg atgccttcct gaatacgtgc gccacccgag tcgttgatac cgataacagg
    13741 ggcacccatc ttcatggcca tatccattac tttacagatc ttttgtgcca tggtttccga
    13801 cagtgaacca ccgaatactg tgaaatcttg tgcgaaaaca tatactaatc taccttctat
    13861 cgttccataa ccggttacca caccgtcgcc gaggaaatgt tttttctctt gtccgaaatt
    13921 ggtacatctg tgttgaacaa acatatccag ttcttcgaaa ctaccttcgt caagcaactg
    13981 tgcaatacgc tcgcgggctg tatatttgcc tttggcgtgt tgtttttcaa tagccttttc
    14041 gccaccacct aaacgagcct gagcacgaag ttcaataagc tcttttactt tttcaagctg
    14101 gttactcatg agtttttctt aatttaaagg gttataatat ttacaaccgg acgattgaca
    14161 acccggatgg ggaatttaat gcaaagaaaa attccgtttg tccgtggcgc ggatcgtccg
    14221 aatcgtacat ctttttagtg ttcgcagagt tctgtcagta cgcccagagt tgatttcggg
    14281 tgaaggaaag caatgttcag gccttcggca cctttgcgcg gagctttgtc gatcaggcgg
    14341 atctctttgc tttcggcttc ggccagggca ttggctacgc cgtcttcaat ggcgaatgct
    14401 acgtgatgaa cacctgcacc tttgttttca atgaatttcg cgatggtact ttccggacat
    14461 gtgggttcca gtaattcgat tttggtatca cctactttca ggaaggctgt tcttactttt
    14521 tgatcttcta cagtttcgat gttgtagcat ttcaaaccta aaacgttttc ataatacgga
    14581 agggcttctt cgatactttt tacggcaatg cccaaatgtt caatgtgtga aatcttcata
    14641 actatatttt taaattttgg tattaatcgt cttttcggaa tggtataaaa cagcacaaag
    14701 a
//
