LOCUS       c00070_gnlPro..        12650 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IMLAKGBC_70.
ACCESSION   c00070_gnlPro..
VERSION     c00070_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 12:40:11
            Original ID  :: gnl|Prokka|IMLAKGBC_70
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12650
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12650
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[63:2650]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      64..2650
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..12650
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12650
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             64..1953
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 202.5; E-value:
                     4e-62)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg70_1"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.5e-62, bitscore:
                     202.5, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 2.1e-29,
                     bitscore: 92.7, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLYTRYEMQDVVIVDGRARGIIAKNLVTGELERFAAHA
                     VVIATGGYGNAYFLSTNAMGCNCTAAISCYRKGAVFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKKEDAVKLQKGEIKGSDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSEAINRLGIDVVLQRYGNLFDMYEEITDVNPGE
                     LAKEISGVKYYNPMMIYPAIHYTMGGIWVDYELQTTIKGLFAIGECNFSDHGANRLGAS
                     ALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAEAEKAVQAKIDKFMSIQGKES
                     VDSIHKKLGHVMWEYVGMGRTAEGLKKGIAELKEIRKEFETNLFIPGSKEGMNVELDKA
                     IRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDEGMAPSWSES"
     CDS             1916..2650
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg70_2"
                     /sec_met_domain="Fer4_7 (E-value: 1.6e-12, bitscore: 38.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 4.6e-25, bitscore: 78.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 7.2e-07, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKVWRQAGPKAKGAFETYQMKDIPGDTSFLEMLDILNEQLISER
                     KEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVEPWRSAGF
                     PVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIAKPIADEAMDAASCIGCGACV
                     AACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTRACEAECP
                     KNISISNIARLNRDFIIAKLKD"
     CDS             complement(3297..4136)
                     /locus_tag="ctg70_3"
                     /transl_table=11
                     /translation="MPSICQGIWDCQICPKAVSNAITHVIYQRGFHKPAQKCEENLILF
                     LMKGEILVNSKEYAGTMLKGGEFILQAIGSMFEMLAMTECECIYYRFIQPELFCDFRFN
                     HIMKEISPPLIYTPLKIIPELQYFLNGSITYLKGDKVCRDLLSLKRKELAFVLGYYYSD
                     YDLSSLVHPLSKYVNSFQYFVIQNYKKVKTVEELAQLGGYTLSTFRRIFNNVFHEPVYE
                     WMLARRKEGILDDLNNSEYSISEICYKYGFESLPHFSNFCKKSFGASPRNLRRQDIS"
     CDS             complement(4390..5391)
                     /locus_tag="ctg70_4"
                     /transl_table=11
                     /translation="MKKILLAVTTALAITGCSQNEEFDAPNQQTKIDFTSVVKKATRAA
                     DTTGDNFLGFTVNSYVTAAAYDGLAALGGDVYMDGISYTRDNAAAPWTTTDKGIYYWPS
                     ISSGKKVQFFAYPTTDPTSYSLPSTGYPTISFAVDDTPAAQKDLVVAHATDVTSETQGV
                     TDGRLTLDFKHVLTRINFAFIPGDPNLTYKVTGISVANVKGGTGIYSFNNADGEWNLTN
                     ASDASYIYNVKQSSTKVENKEYYSLAGANASWMLFPQEVGGKIISITYSTEQGSMEVFK
                     GTKTVTLPDNAKWTLGQNVLYVLTLPAGASNVGIDTNVSNWNSTSEDAETAK"
     CDS             complement(5446..6399)
                     /locus_tag="ctg70_5"
                     /transl_table=11
                     /translation="MLTGCSRRDILDDYPVSGVDIKLDWDGVTDQLPEGVRVIFYPKNG
                     DGRKVDKYLSVRGGEMKVPPGRYSVVVYNYNTESIRIRGEESYETIEAYTGNCNGLGIE
                     GTEKMVWSPDSLYVLNIDELKIEKSEEVLRLDWKLESVVKKYSFAVEAKGLEYVATVVG
                     SIDGLSDCYCIGKGRGVCSSQPIYFEVKKGDNKVTAFFTAFKQVKEMTMPTRMSTSERE
                     TSSEKGAIILILKFIKTDNTVQEATIDVTEIIGTLENAGTGEDGKPTPPPEIELPPDDK
                     IEVDKPETPPNPDGGGGMGGNVDGWGPEDNVELPVN"
     CDS             complement(6457..7776)
                     /locus_tag="ctg70_6"
                     /transl_table=11
                     /translation="LFSNFYICHQKRTTMKHGIYILTILMALLSLPESGYASIPFFAVA
                     NDTIRRVVIYFDANEAKVDLSYKSNNQVITILDSLLLGNLNTKYITALNVETFVSPDGD
                     ESYNRSLAARRNDSIKEFLQRYNSDVSVDKIHFFSEGEDWSEFRKLVASDSNLPDREEV
                     LILIDYHKNDVNKRKQLLRKLNRGIAYRYIVHNIFPELRRSVITIVGETSKLGKEAFEP
                     VSSVSGLFVSKQEEALPKDQPDKPVGESEKKQACEVDISEAEGPVKSQTVLAVKNNLLY
                     DLALAPNIEVEIPIGKRWSLNTEYKCPWWLNGKHDFCYQLLSGGMEGRCWLGNRQKRDR
                     LTGHFIGLYAEGGIYDFQLRGDGYQGKYYGVAGVTYGYARQLARHFSLEFSLGIGYLTT
                     EYKKYTPYEGDIIWTNSGRYNFIGPTKAKVSLVWLITTKK"
     CDS             complement(7783..8103)
                     /locus_tag="ctg70_7"
                     /transl_table=11
                     /translation="MISLMKFLGGDKISRRKFLATPDHSYFPICIEAMKLGIHVYVEKP
                     LVRTSYECELFAGGTEVRCYHADELPRTFFLFIIDLKLSKLAKSFQSFHRIFHVLIFVL
                     KV"
     CDS             complement(8201..8494)
                     /locus_tag="ctg70_8"
                     /transl_table=11
                     /translation="LKTKDEIIAILRNFKEEFGERYGIEKLGLFGSVARGEQKEDSDID
                     ICVKLQDPDYFTRMEIKESLEERFNAKVDVVSLTAIMRSLFRNHIEKDAIYI"
     CDS             complement(8710..9975)
                     /locus_tag="ctg70_9"
                     /transl_table=11
                     /translation="LCAIVMMVISMTAFAQEDVFSGDWLGANKEGDLKVAFTLNCDGNW
                     QLNPYNENARCNGFMEVNMLEPGGRESLMATYEFYVESMNGNELTLSFVGGRPEVDAGI
                     SGQCKVVYKDDKLSFSGLDKGGKDAAFNGLTLVKSGSGADAIADAAADDGVPLGVKILA
                     VVQLVLSIAVVLFIVGHMFFVWYKGARYKEVFTVEGMLNKRLAAGMPEKMTDEEITEAW
                     KLMDEAFATWTVIEKTDDDEFRKPTKMKQIKKSVLLIDQVIGMCPTDADVIERLNSLTD
                     VINSGEERHFDGSRKLIWLGVIVGILMYWMMGVGMMFSTLIATGLYVVASRTPQFLIDK
                     RALRGGGNIHNGIFAGVFGLLAGAQTVRTIYKFNDGHKEYSDDHSQHWIALAIGLVVLF
                     VLAMMMAFWALLNYLRNYVLYF"
     CDS             complement(10009..11583)
                     /locus_tag="ctg70_10"
                     /transl_table=11
                     /translation="MRKNRIRILSMVVFSLCLPFSLFAQIDKDMKEFDDFVKQQHKEFD
                     DFVSEQNKEFAEFLKETWKEYDLQKPVVRPQRPEPVKPVSFDRKKPATKPQEVKVGEVT
                     RLPIPTVTPSATFSPSKGKTPVPVIPGGKDVTVEPEKDSAVLPEIKPEVKPEETVPAKR
                     SLSGVEFSFYSKDCVVNASLKNRLTLKGIAEKDISAGWETLSRSNYQPLIDDCLAFKKE
                     IALNDYGYLLLTRKVATELCGSTHSDEIALMQMFLLSQSGYRVKVARMDNRLTLFYASG
                     NMIYATCFITLNGVNYYRFDTTPNKTNSIYTYNRDFANAKNPVNMNITTPQPFSGTYVE
                     KTLQAKAYPSVKVCSKVNSGLISFYKDYPQCGFSVYVGAPVSQEVQQTVLPSLQAAIQG
                     KKQSEAANILINFVQTAFDYKTDGDQFGYEKPFFVDELFYYPYSDCEDRAVLYSYLVRT
                     LMGLDVVLLEYPNHMATAVCFDENIDGDYITVSGKKYIICDPTYIGASIGLAMTQFKNV
                     AAKVLKY"
     CDS             complement(11580..12572)
                     /locus_tag="ctg70_11"
                     /transl_table=11
                     /translation="LSDIRYNWVVIFIIQLLLSPGIDVFSQAMPVDTVYNQSYDWRPGQ
                     RETLPEWVFASQRKGRVVGISDPCMKSEAARMLALQRAAYLYSLQQGVQLRLLSDVFST
                     METASNTYEDQRNKMLVLGVIEHPVQHVSYRIEHEYTSIFGEKFLEVSFTPSNDSCDFS
                     YHSISELMLLFTKERVEEEEVKFNLLLESDSCREQSDQSWFQLKGTQSSPQIISYMNGV
                     EICSSQEGCWYEDAGFGDQDGLEKMDMRNAFWNAYMSSLVKALLLYPFSDVNVKQVDDR
                     FNGGTDSGCGLYREKVVAVLSISPFIKDIRNNKLYVDWQITEQQNIIRK"
ORIGIN
        1 cactgatttg tggcggtgct tgctaaatag taaattgtaa atgattaaat tgtaaataat
       61 attatgatca agatagattc aaaaattcca gaaggcccgg tggctgagaa atggaccaac
      121 tataaagctc accagaaatt ggtgaacccc gctaataaac gtcgtttgga catcatcgtt
      181 gtgggtacgg gtctggcagg tgcttctgcc gctgcttcac ttggtgaaat gggtttcaga
      241 gtattcaatt tctgtattca ggattctccc cgtcgtgcac actctatcgc tgcacagggt
      301 ggtatcaacg ctgcaaagaa ctatcaaaat gatggtgact cggtttaccg tctgttctac
      361 gatactgtaa aaggtggcga ctatcgtgcc cgtgaagcaa acgtatatcg tttggctgaa
      421 gtgtctaacg ctatcatcga ccaatgtgta gcacaaggtg ttcctttcgc tcgcgaatac
      481 ggtggtacac tggacaaccg ttctttcggt ggcgcacagg tatcccgtac tttctacgct
      541 aaaggccaga ctggtcagca gttgctgctg ggtgcttact ctgcattgag ccgtcaggta
      601 aacgtaggta ctgttaaact gtatacccgc tatgaaatgc aggatgttgt catcgttgac
      661 ggacgtgccc gcggtatcat cgcaaaaaat cttgtaacag gcgaattgga acgtttcgct
      721 gctcacgctg tagtaatcgc tactggtggc tatggtaacg cttacttcct gtctactaac
      781 gctatgggtt gtaactgtac agctgctatc tcttgctacc gcaagggtgc tgtattcgct
      841 aaccctgctt acgttcagat tcacccgact tgtattccgg tacatggcga caagcagtct
      901 aagctgactt tgatgtctga atctctccgt aacgacggtc gtatctgggt tccgaagaaa
      961 aaagaagatg ctgtgaaact tcagaaaggc gaaatcaaag gaagtgatat tcctgaagaa
     1021 gaccgcgact attacttgga acgccgctat ccggcattcg gtaacctggt tccgcgtgac
     1081 gttgccagcc gtgccgctaa agaacgttgc gacgctggtt tcggtgtaaa caacacaggt
     1141 ttggccgtat tcctcgactt ctctgaagct atcaaccgtt tgggtatcga cgttgttctt
     1201 caacgttatg gtaacctctt cgatatgtac gaagaaatca ctgacgttaa tccgggcgaa
     1261 ctggctaaag aaatcagtgg tgtgaaatat tataacccga tgatgattta tccggctatc
     1321 cactatacaa tgggtggtat ctgggtagac tacgaactgc aaaccactat caagggtctg
     1381 ttcgctatcg gtgaatgtaa cttctccgac cacggtgcaa accgcctcgg tgcttctgca
     1441 ttgatgcaag gtttggctga cggttacttc gtattgcctt acactatcca aaactatctg
     1501 gcagaccaga tcactgttcc tcgtttctct accgatcttc ctgaatttgc tgaagctgaa
     1561 aaagcagttc aagctaagat cgacaagttc atgagcatcc agggtaaaga atctgttgat
     1621 tctatccaca agaaactggg tcatgtcatg tgggaatatg taggtatggg acgtacggca
     1681 gaaggcctga agaaaggtat cgccgaactg aaagaaatcc gcaaggaatt cgaaacgaac
     1741 ttgtttatcc ccggttctaa ggaaggtatg aacgtagagc ttgacaaagc aatccgtctg
     1801 tacgacttca tcactatggg tgagcttgtt gcttacgatg cattgaaccg taacgaaagt
     1861 tgtggtggtc acttccgtga agaataccag actgaagaag gagaagcaaa acgtgatgac
     1921 gaaggtatgg cgccaagctg gtccgaaagc taaaggtgct tttgaaacct accaaatgaa
     1981 agatatcccc ggtgatactt ccttcctcga aatgctggat attctgaacg aacagctcat
     2041 cagcgaaaga aaagaaccgg tagtattcga tcatgactgc cgcgaaggta tctgcggtat
     2101 gtgttctctt tacatcaacg gacacccgca cggtcctgca acaggtgcta ctacttgcca
     2161 gatctatatg cgtcgtttca acgacggtga taccatcact gttgaacctt ggcgttcggc
     2221 tggtttccct gtcatcaaag acttgatggt agaccgtact gcatacgaca agattatgca
     2281 agctggtggt tatgtaagcg tacgcacagg tgctccgcag gatgctaacg ctatcctgat
     2341 cgcgaaacct atcgctgacg aagctatgga tgctgcttct tgtatcggtt gcggtgcttg
     2401 tgtagctgca tgtaagaatg gttctgctat gttgttcgtt tctgcaaaag tcagccagtt
     2461 gaacttgctg ccgcaaggta aaccggaagc tttgcgtcgt gcaaaagcta tgttgtcaaa
     2521 gatggatgaa ctgggattcg gtaactgtac aaacactcgt gcttgtgaag ctgaatgtcc
     2581 gaaaaatatt tctatcagca acatcgctcg cttgaaccgc gacttcatca tcgcaaaatt
     2641 aaaagactag aaattgctag atttcaatag cgagagctta atttgattaa tgacagaatc
     2701 ccctgccggc tagtccgaca ggggatttct ttatgtatga gtagatcaca attattatta
     2761 atacggatca gtaacatgaa cttttaattc ataagtttca ccgatttcac cttatagcca
     2821 gaactgttat gaatgagaga attacgggtg aaagcgagga ttgaaataag gtaaaatcat
     2881 tcattaccgc tttcacctgt cttattaaaa tatcccttga gctaaaacaa ttatcattat
     2941 agctaatccg gatatgctta tagcaaatcc gctttcaggt gttaatgagt gaactgtgcg
     3001 gatgtaatac tttggccgac aggtcttaac accttagttc tcatgtgtta atacttgagt
     3061 tgttgcatct atatatccag catcttggag ctatatatcc aacaccttga agctatatat
     3121 ccaacacttt ggatctatat gtccaacagt cggtatgaat aaactcaata ggtgaaaccg
     3181 ggaaggttca gtttcacctg aatttctccc ttgctttcac ccgctgttac cttattcatc
     3241 ggcatttaga gaattggatg aaaccggtga accgcagtta tcttacatag ttgcatttat
     3301 gaaatgtctt gcctacgtaa attacgtgga gaggcaccaa aagatttctt gcagaaatta
     3361 gaaaaatggg gtaaagattc aaaaccatat ttatagcata tctccgagat gctatattca
     3421 gagttgttca agtcgtccag aatgccctct ttacgtctcg ccagcatcca ttcataaaca
     3481 ggttcatgaa agacgttatt gaagatacga cggaatgtac taagagtata tccacccaat
     3541 tgtgccagtt cttccacagt ctttactttc ttatagtttt gaataacgaa atattggaaa
     3601 ctgtttacat atttagagag tggatgcacc aagctcgaaa gatcataatc ggaataatag
     3661 tatcccaaca cgaacgctaa ttcttttcgt ttcagagata gcaaatcccg acagacttta
     3721 tctcctttca aataagtaat agacccattg aggaaatatt gcagttctgg aattattttt
     3781 aatggagtat aaataagtgg aggagatatt tccttcatga tatgattgaa acggaaatca
     3841 caaaacagtt cgggctggat aaaacgataa taaatacact cacattcagt catagcaagc
     3901 atctcaaaca tagaaccaat agcctgaagg ataaattcac ctcccttaag cattgtccct
     3961 gcatattcct tactattgac cagtatttct cccttcatca aaaaaaggat aagattttct
     4021 tcacactttt gagccggttt atgaaaacca cgctgataaa tcacatgagt aatagcatta
     4081 ctcaccgctt ttggacatat ttgacaatcc cagattcctt gacaaataga tggcatacgc
     4141 tgactgtgtt tgtttttgtt tatgctgcca gcaaaaatat atgaaatctt tcatattgcc
     4201 ataaaaaaag agagaaaagt gaaaaagagg ttgaagagag gaggaggaaa aaaagaaaaa
     4261 acataatttc aatctaaacc aacattcaat ttagcttttt taaacaagaa ttcccagctt
     4321 gttctttgga aaagctggga atccgaaaat agcaacttaa tttttcagtg taagaatact
     4381 tatactaact catttagcag tttctgcatc ttctgatgta gaattccaat tactaacatt
     4441 tgtatcaata ccaacattag acgcaccagc aggcagtgtc aatacataca atacattctg
     4501 gcctaatgtc cacttcgcat tatcaggaag agttactgtt ttagtcccct taaacacctc
     4561 catactacct tgttctgtag aatatgttat tgatataatt tttccaccaa cttcttgagg
     4621 aaataacatc caagaagcat tagcaccagc taatgaataa tactccttat tttcaacctt
     4681 agttgatgat tgcttcacat tataaatata agaagcatca gaagcattag tcaaattcca
     4741 ttcaccatca gcgttattaa aactatatat acctgttcca cctttaacat tagctacact
     4801 aataccagtc actttataag taagatttgg gtctccagga ataaatgcaa aattaatacg
     4861 agttagaaca tgtttaaaat ctaaggtcaa tctaccatca gttaccccct gtgtctctga
     4921 agttacatca gtcgcgtgtg caacaactaa atctttttga gctgcaggag tatcatcaac
     4981 agcaaaagaa attgtaggat agccagtaga tggaagagag taagacgtag gatccgttgt
     5041 cgggtatgca aaaaattgta ctttctttcc tgaacttatc gatggccaat aatatattcc
     5101 cttatcggta gtagtccaag gtgcagcagc attatctctt gtatatgaga ttccatccat
     5161 gtatacatct cctcctaaag cagctaatcc atcataggct gcagctgtga cataagagtt
     5221 cactgtaaat cctaaaaaat tatcaccagt tgtatctgca gctcttgtag ctttctttac
     5281 tactgaagta aaatcaatct ttgtttgttg attcggagca tcaaattctt cattctgtga
     5341 gcaacctgta attgctaaag cagttgtaac tgccaataaa atcttcttca taactgtatt
     5401 tttttaagtt tataatattg ttatattttg tttatagcat ctatttcaat tcacgggtaa
     5461 ctcaacatta tcttcgggtc cccatccatc aacattgccg cccattcctc cacctccatc
     5521 aggattcggt ggtgtttccg gcttatcaac ctcaatctta tcatcaggcg gtaactcaat
     5581 ctccggtggt ggggttggct ttccatcttc ccctgttcca gcattttcaa gtgtacctat
     5641 tatttcagta acatcaattg ttgcttcctg aactgtatta tctgttttga taaatttcaa
     5701 tattaatatt atagcacctt tctcactaga agtttctctc tctgatgttg acattcgcgt
     5761 cggcattgtc atttccttta cttgtttgaa agcggtgaaa aatgccgtta ccttattatc
     5821 tcccttcttt acctcaaagt agataggttg tgagctacac actccacgac ctttgcctat
     5881 acagtaacaa tcggataatc catcaatgct tcctaccact gttgcaacat actccaaacc
     5941 tttagcctct actgcaaaag aatatttttt caccacagat tccaacttcc agtctaagcg
     6001 aagcacttct tcactcttct ctattttcag ctcatctata ttcaacacat acaatgaatc
     6061 cggtgaccaa accatctttt ccgttccttc aatccctaaa ccattgcagt ttcccgtgta
     6121 ggcttctatc gtttcatagg actcttcacc cctgattcgt atagattccg tgttatagtt
     6181 gtagactact accgaatacc gtcccggagg aactttcatt tctccgcctc gtaccgaaag
     6241 gtacttatct actttcctgc catccccgtt cttcggataa aaaatcaccc gaactccctc
     6301 cggcagttga tctgtcactc catcccaatc cagctttata tctaccccac ttacgggata
     6361 atcatccaat atatcgcgac ggctacatcc agttagcatc agcagcgagg acaaaagcac
     6421 aagaaaccca tatcttgtat ttcgcattac gccctcctat ttctttgttg ttatcaacca
     6481 taccaaagaa actttcgcct tggtagggcc aataaagtta taacgtccac tatttgtcca
     6541 tataatatct ccctcataag gagtatattt tttatattct gttgtcaaat accctatgcc
     6601 aagactgaat tcaagagaaa aatgccgtgc caactgccgt gcatatccat aagtcactcc
     6661 cgcaactccg taatacttac cttgatagcc gtctccacgc agctggaagt catatatccc
     6721 accttcagca taaagtccga taaaatgtcc ggtcaatcgg tcacgtttct gacggtttcc
     6781 cagccaacaa cgtccttcca tccctcccga aagaagctga tagcagaaat catgtttgcc
     6841 attcagccac cacggacatt tatattcagt attcaaagac cacctcttgc ctatcggaat
     6901 ttccacttct atatttggcg ccaatgccaa atcatataac agattattct tcactgcaag
     6961 tacagtttgg cttttcaccg gcccttctgc ctccgatata tcgacctcac aggcctgttt
     7021 tttttcactt tctcccacag gcttatcagg ttgatctttc ggaagcgcct cttcctgctt
     7081 tgaaacaaac aacccggaga cagaagatac cggttcaaaa gcctctttac ctaatttcga
     7141 agtttctcca acaatcgtaa tgaccgatcg ccgcagctct ggaaagatat tgtgaacaat
     7201 gtatcggtaa gcaattcccc gattcaattt tcgcaacagt tgctttcgtt tattgacatc
     7261 attcttatga taatcaatca atatcagcac ttcttcccga tctggcaagt tggagtcgga
     7321 tgccaccaac ttacgaaact ccgaccaatc ctctccctct gaaaaaaaat gaatcttatc
     7381 aacactaaca tccgaattat accgttgtaa gaattccttt atcgaatcat ttctccgagc
     7441 agccaaactt ctattataag attcatcacc atcaggagaa acaaaagttt ccacattcag
     7501 cgctgttata tatttcgtat tcaagtttcc gagaagcaaa gaatctaaaa ttgtaattac
     7561 ctgattatta cttttataac taagatccac tttcgcttca ttcgcatcaa aatatatcac
     7621 cacccgccgg attgtatcat tcgcaacagc gaaaaatgga atcgaagcat acccactttc
     7681 tggaaggctt aataaagcca taagaatagt caatatatag ataccatgtt tcattgtcgt
     7741 tcgtttctga tgacaaatat agaagttaga aaacaaaccg aatcatactt ttagaacaaa
     7801 aatcaagaca tgaaagattc tgtgaaacga ttgaaacgat tttgcaagtt ttgagagttt
     7861 aaggtcaata ataaacagaa aaaatgtcct tggtaactca tctgcgtgat aacaccgtac
     7921 ttctgttccg cctgcaaaca gttcacattc ataggaagtt ctgacaagcg gcttttccac
     7981 atacacatgg ataccaagct tcatcgcctc tatacaaatc ggaaaataac tatgatcggg
     8041 agtcgccagg aattttctac gagatatttt atccccaccc aaaaatttca ttaaagaaat
     8101 catgtatcaa agtgggttta tgaatagatc acatttctat aaggagttta caaagcggat
     8161 gggagtggta cctaaagact accgttttgc ataataaaaa ttagatatag attgcatctt
     8221 tctctatatg attgcgaaat aaactacgca taattgcggt taaagacacg acatccactt
     8281 ttgcattaaa acgctcttct aatgactctt ttatttccat tcgagtaaaa taatccggat
     8341 cttgaagctt tacacaaata tcaatatcac tatcctcttt ctgctcacca cgagccacag
     8401 aaccaaaaag tcccaacttt tcaattccat atctctcccc aaattcttcc ttaaaattcc
     8461 ggagaatagc gattatttca tcttttgttt tcaattgaca ctattgttat aatgcaaatg
     8521 ttaaaattta tattggaatt agcaagttct taatcatatt ttatagtatc actaattaaa
     8581 aaaagatgca caggtcatcg aattttcatc gatcccctgt acacctacta ctctaaattc
     8641 tacttcaaaa cataaatagc ctaattatgc tgccgaatcc attattaaca accatgttag
     8701 ttttatccat caaaagtaca gaacataatt acgtaaatag ttcagaagtg cccagaacgc
     8761 catcatcatt gccaatacaa acaaaacgac aagtccgatt gccaaagcaa tccaatgttg
     8821 tgaatgatca tcagaatatt ctttatgacc atcattaaac ttgtatattg tccgcactgt
     8881 ctgcgctcct gccaataacc cgaacactcc ggcaaaaata ccattatgaa tgtttccacc
     8941 gccacgaagt gcccgcttat caattaagaa ttgaggcgtc ctgctcgcta ccacatacaa
     9001 accggtagct attaaagtag aaaacatcat accgactccc atcatccaat acatcaagat
     9061 acccacaatg acacctaacc agattaattt cctggaacca tcaaaatgac gttcttcacc
     9121 actattaatc acatcagtca atgagtttaa gcgttctatg acatcagcat cagtaggaca
     9181 cataccgata acctgatcaa tcaaaagaac agatttctta atttgcttca tctttgtcgg
     9241 ctttctgaat tcatcatcat ctgttttttc aatcaccgtc caagtagcaa atgcctcatc
     9301 catcagcttc cacgcctccg ttatctcttc atccgtcatt ttctccggca ttccggctgc
     9361 aaggcgttta ttcaacattc cttctaccgt aaaaacctct ttataacgtg cgcccttata
     9421 ccatacaaaa aacatatgcc ccacaataaa taaaacaacg gcaatagaca aaaccagttg
     9481 gacaacagcc aatatcttta ctcccaaagg aactccgtca tccgccgcag catcagctat
     9541 tgcatcagct ccactaccgc tttttacaag tgtcaatcca ttaaaggcag catcttttcc
     9601 gcctttatca agtccggaaa acgacaactt atcatcctta taaacaactt tgcattgacc
     9661 ggaaatcccg gcatcaacct ccggacgtcc gcctacaaaa gaaagagtca gttcattccc
     9721 gttcatactc tcgacgtaaa actcataagt tgccatcaaa gattcccttc caccgggttc
     9781 cagcatattc acttccataa atccattgca tctggcattc tcattataag gattcaattg
     9841 ccaattacca tcacaattca atgtgaacgc aacctttaaa tcgccttctt tatttgctcc
     9901 tagccagtca ccgctaaaaa catcttcctg cgcaaatgca gtcatcgaaa taaccatcat
     9961 tacaatggca cacaaatact ttttaatatt cttcataata taataaaatt aatatttcaa
    10021 caccttagct gctacgttct taaattgcgt catggcaagc ccgatagaag ctccgatata
    10081 agtaggatca caaataatgt acttctttcc gcttacagtt atataatctc cgtcaatgtt
    10141 ttcatcaaaa cagaccgctg ttgccatgtg attgggatat tccaacaata caacatcaag
    10201 ccccataaga gtacgtacca aataagagta taacacagca cggtcttcgc aatcggaata
    10261 aggatagtag aacagctcat ccacaaagaa aggcttttca taaccaaact ggtcaccatc
    10321 tgtcttataa tcaaaagctg tctgcacgaa attaatcagt atattagcag cttccgattg
    10381 ttttttccct tgtatggcag cttgcaatga tggaagcacc gtctgttgta cttcctgact
    10441 gacaggagct cccacataga cagaaaagcc acattgcgga taatccttat agaaagaaat
    10501 aagtcccgaa tttactttcg agcagacttt gacggatgga taagctttcg cttgcaacgt
    10561 tttctccacg taagttcctg aaaagggttg aggagtagtg atattcatat ttaccgggtt
    10621 cttcgcattg gcgaaatcac ggttgtaagt gtaaatagaa ttagttttat tcggggtagt
    10681 atcaaacctg taatagttta ctccattcaa agtaataaaa caggtagcat aaatcatgtt
    10741 acccgaagca tagaataaag taaggcggtt atccatacgc gccaccttaa ccctatatcc
    10801 cgattgagaa aggagaaaca tttgcataag agctatttca tcggaatgag tacttccaca
    10861 tagttcagta gccactttcc tcgtcaacag cagatagcca tagtcattca gggcaatctc
    10921 ctttttaaaa gccagacagt cgtctatcaa aggctgatag ttgctacgcg ataacgtctc
    10981 ccatccggca gaaatatctt tctctgcaat cccttttaaa gtgagccggt tcttcaatga
    11041 agcattgaca acacaatctt tactgtagaa cgaaaactct acaccggaaa gcgagcgttt
    11101 ggccggaacg gtttcttcag gcttcacttc cggttttatt tcagggagca ccgcagaatc
    11161 cttttccggt tctacagtaa catctttacc tcccggtata actggaaccg gtgttttccc
    11221 ttttgaagga gaaaatgtcg cacttggagt cactgtcgga atggggagcc gggtcacctc
    11281 ccctacttta acctcttgcg gttttgttgc cggcttctta cggtcaaagc taaccggttt
    11341 tacaggctct ggtctttgag gacgtaccac cggcttctgc aagtcatact ctttccaggt
    11401 ttctttcaga aattcggcaa attccttatt ctgttcactc acaaaatcat caaactcttt
    11461 gtgctgctgc ttcacaaaat cgtcaaactc cttcatgtct ttatctattt gcgcaaaaag
    11521 actaaacggc aaacacaatg aaaaaactac catagatagt attcgtatcc tatttttcct
    11581 catttcctta ttatattttg ttgttctgtt atctgccaat ccacatacag cttattattc
    11641 cgtatatctt tgataaaggg ggaaatggac aagacagcga caaccttctc ccgatacaaa
    11701 ccacaaccgg aatcagtgcc gccattgaaa cgatcgtcca cctgcttgac atttacatca
    11761 gaaaacggat ataacaacag tgccttcacc aaagaagaca tataggcatt ccaaaaggca
    11821 ttcctcatat ccatcttctc caatccgtcc tgatctccaa aaccggcatc ttcataccaa
    11881 cagccttcct gtgaagaaca aatttcaact ccgttcatat atgaaattat ttgaggagat
    11941 gactgtgttc ccttaagctg aaaccatgac tggtctgatt gctccctaca actatccgat
    12001 tccaacaata aattgaattt cacctcttct tcctcaaccc tttctttcgt aaacaaaagc
    12061 atcaactcac taatggaatg ataagaaaaa tcgcaactat cattcgatgg agtaaaagat
    12121 acctccagaa atttctctcc aaatatagaa gtatattcat gctcaatccg gtaggaaaca
    12181 tgttgaacgg gatgttcgat cactcccaat acaagcattt tgtttctttg gtcttcgtat
    12241 gtattactgg cagtctccat ggtggaaaaa acgtccgaga gaagtctcaa ttgtacccct
    12301 tgctgcaatg aatacagata agccgctctt tgcaaagcaa gcatccttgc agcttcggat
    12361 ttcatacaag gatcagatat accaactacc cggcctttcc gttgagaagc aaacacccat
    12421 tccggcaaag tctcccgctg tcccggtctc cagtcataag attggttata aactgtatca
    12481 acaggcattg cctgtgaaaa cacatcaata ccgggagaca aaagcaactg gataataaaa
    12541 ataactaccc aattatatct tatatccgac aaattaagtt tcatcattca atcttcaaat
    12601 agttggggag ttattaaaga gatcattact atcctctgtg ttctaaacaa
//
