LOCUS       gnlProkkaNKPBJDDJ_17   10520 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NKPBJDDJ_17.
ACCESSION   gnlProkkaNKPBJDDJ_17
VERSION     gnlProkkaNKPBJDDJ_17
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 11:06:59
            Original ID  :: gnl|Prokka|NKPBJDDJ_17
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10520
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10520
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[4104:9765]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4105..9765
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..10520
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10520
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             3..455
                     /locus_tag="ctg17_1"
                     /transl_table=11
                     /translation="MIIIPVQILSVVILGRFFMRTSQEVIKRVLSFILFFSLFLFIILF
                     IAKRYILTYYSFSLVSDVLWSFSLVLFSSLFANLSVFIGDNIMISNSLEKQLIKSSIYS
                     SLFVFPLLIITLCFVDNSLFTLSVFFLFHKILEFLLRVYYSWNYIN"
     CDS             437..1828
                     /locus_tag="ctg17_2"
                     /transl_table=11
                     /translation="MELYKLKNRNNIILLLKIQYLNFALSILLFIVNLISGATINYLFF
                     SYYLLFSFLYITVVSLKVFSLASAFNLFLFGYFMFQISALFVSLDTLLERKLMDNLFLF
                     SEEQINNTLCANSIILNAMFLGCLMSIIYLPIKTNINKANLIYSERLQNWGYLLFWAAL
                     PFTLLKFYLEIKLVLTEGYYAYYTSSLSIPFLISISRFIFEIGFFLFLTSLPPKKKFLT
                     VSKVYILVMCLFFLIGVRNRVILSFLFVLWFYYRFYSKKSPKILFLLIISISSVALLLL
                     VQLVRQAGVFLLSDDRSIFSYFFYAQSTNFYILPLLQYYDLHTEVPFVFAPFFNLDTSY
                     YDPNGINNLLGNAIAFRISPDEFREGHGLGSSFIAELYDLGIVFMSILSIGLGFVMGWF
                     ERNVKNNRALLAISFYAITNCIYISRSSLFRNVYMFPLLIILVFIALKIRYPFKMKKNE
                     YPTRL"
     CDS             1806..2930
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_3"
                     /sec_met_domain="Glycos_transf_1 (E-value: 8.4e-25,
                     bitscore: 76.8, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNILHVSDIDVSSCGGGMNTVIPELIMRQLLYDSTLNETLFITRK
                     KYKIAKQIPYFICFMEGNFLKYLQKSDLLVFHSVYNLKFILLYFFCKKNKLPYLIVSHG
                     GLSKVALKKGIIKKKLFKFLFLNRFVKDATVLCFTSLEEQLSSVYTDKKYIIVPNPIQI
                     SDYSYRLDVSNNDEVKMIFLSKIDFYYKGLDVLFDALNIIKEDIVNANVFLSFYGYGKN
                     KEVDVENINSAEKDILKLILRIKELNIGERIKYCGPVFGHQKMEVLKNSDIYVLTSRSE
                     AMPLSISEALSVGTPCLVTHGTNMSNLIEQYKAGWSSSLNKEDLAFNILKAIKEYKDSP
                     VTFRKSARGLYEYNSSIDVGKVSIDQYKTILEEK"
     CDS             2930..4114
                     /locus_tag="ctg17_4"
                     /transl_table=11
                     /translation="MLYYFRIFISYLLYEFGVRRKDIIIFSGYKNLKYNFNSRYLFEFF
                     LEKKSNLKCFFVIDDDNLRRRLNEIVGDYFVTTNSWKDLKLIFSAGTWITSGGLPIRIP
                     YVNRNRVVVNLWHGLPFKGIGLLNNENTCLQNLLIYWVYSKYDLFSSTSELFQQIFARS
                     FSINSKSVKILGQPWNDQLWNENDKYEVLGDIYGDNLPSFYKVFLYAPTWRSGRCTSFF
                     PFKDFSKNRLESFLEKYQLLICLRTHQLEANRVKDYVSCKRVLLLNEDRVTDIMSILNI
                     FDGLISDYSGIIFDYLLLDRPIILLPYDKEEYTSERSVNFNIDSFEFAPPPYNIDSFFS
                     LLQKAVCCKCISQKQLRFKNVVHYYIDNNSCQRHYEEIMKLIKMKNNKQVKKWI"
     CDS             4105..5418
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 203.9;
                     E-value: 5.2e-62)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_5"
                     /sec_met_domain="CTP_transf_like (E-value: 1.9e-16,
                     bitscore: 50.0, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 3.3e-119, bitscore:
                     386.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.5e-65, bitscore:
                     210.5, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDIEKKKTVYVGMSADIIHPGHLNIISEAQRLGKVTVGVLTDAAI
                     ASYKRLPYLNYEQRSLIVKNIKGVDEVIPQTTLDYVPNLKLLKPDFVVHGDDWKEGIQK
                     ETRQKVIDTIAKWGGKVIDIPYTKGISSTQLNEKLKEIGTTPEVRLKRLRRLIEAKSVV
                     RICESHSGLTGLIIENTVVEVNGVKREFDGMWSSSLTDSTSKGKPDIEAVDLTTRLHDL
                     NDALECTTKPIIFDGDTGGKIEHFVFTVRTLERLGVSAVIIEDKVGLKKNSLFGTDAVQ
                     LQDTIEGFSEKIKAGKLAQITTDFMIIARIESFIAGKGLEDAIERALAYVEAGADGIMI
                     HSKDKSGEDIKKFCYAFRQLNKSIPIVVVPTTYNHITETELASWGVNVIIYANHLLRSA
                     YPAMLNTAKIILANERSFEANDLCMSVREILELIPGTK"
     CDS             5428..6591
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 73.2;
                     E-value: 3.2e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_6"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.6e-15, bitscore:
                     46.5, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.4e-22, bitscore:
                     68.3, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSPKFFVETLQTYSMDFFTGVPDSLLKNMCAYITDHIESQNNII
                     AVNEGTALGLAAGYYIATGCIPIVYMQNSGIGNTVNPLLSLTDKVVYNIPVLLLIGWRG
                     EPGIKDEPQHIKQGMITIPLLDTLGIKNQILNKDPNMAKSQINDAIEYMRMTKEAFAFV
                     IQKDTFEEYKLQNTEDSKFDLDREEAIKIVCNSLDKGSVIVSTTGMISRELFEYRESID
                     ANHETDFLTVGSMGHASQIALGIALRRKNKKVYCFDGDGAVLMHMGALTTIGTSRAVNY
                     IHIVFNNGAHDSVGGQPTVGLKVNLSKIASACGYNNVISVDSKATLKESLDRFKSINGP
                     VLLEVKVRKGARKDLGRPTLTPVKNKELLMNFLEEADESDKSDNVFK"
     CDS             6557..7699
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Fe-ADH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_7"
                     /sec_met_domain="Fe-ADH (E-value: 9.1e-76, bitscore: 244.3,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQINQIMCLNNDPFEYLQSNLSRYSSRKLFLVRGKKSYELCGAK
                     RVVEDVISNLKCGFVEYFDFSENPKYEDLERGLKLLELSGADLIVAIGGGSVLDMAKLI
                     RFFHSYSGDILNEKFVKNRDLLPLFAIPTTAGTGSEVTHFAVLYKDNLKYSVSHKDMLP
                     DRAIICPQFTYKNARYLTACTGFDALSQAIEAYWNVYSIEESDNYSIKAIKLIWDNLPL
                     VIDSSTNELRDKIAEGAYWAGKAINITKTTAPHAFSYPFTINYGYPHGHAVALTFPFFM
                     RYNYAELENKLHPLLNSKSHCKKMEQLYNMLGSTFDMIYDDMYNYLERIGLAINIRGRN
                     FDKNLILHGINASRLSNNPCVLSQADVDFIVDEFVENGKL"
     CDS             7701..8513
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_8"
                     /sec_met_domain="Glycos_transf_2 (E-value: 8.3e-23,
                     bitscore: 70.5, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLCVIMSIYKNDNLLAVTQSIESILRQAYEKIEFYIQLDGEIRS
                     DVLQYLRGLCIQDIRVKILNRTLNRGLAYSLNELLNIVLTKEYEYIARMDADDISMPER
                     FVKQIAFMNSHPDIDCLGTWAIEIDDDGKEYFRKKMPITHEECLELFKKRDCMIHPTVM
                     FRRSYFEKAGLYPEDTYFGEDTMMWAKGFKSGCKFANVPEYLFKFRLDSNFFERRRGWK
                     HAKSIYTLRHRVNRMLGFGWKEDCYALLYAMAKLMPKSILDIIYKTVR"
     CDS             8542..9765
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     269.2; E-value: 9.7e-82)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_9"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2.2e-44,
                     bitscore: 141.5, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4.1e-08, bitscore:
                     22.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIPFSPPYIDEAVINEVVDSLRSGWITSGPKVKALEEEIKSFSG
                     AKEVLCVNSWTSGAIMMLRWLGVKEGDEVIVPAYTYSATALAVLHAGAKPVMVDSGTDF
                     NISVEAVRKAITPKTKAIIPVDIAGFPCDYERIMALVQEPEMVKLFRSESPVQEKLGRI
                     LVMNDAAHSLGARYSSRQRTGCETDVAIFSLHAVKNVTTAEGGAICLNLPKPFDNTELY
                     KELRMTSLNCQTKDAFSKSKAGGWRYDIVGFGMKINMADVNAAIGLAQIREYPELLKER
                     KRVFNAYSDAFSACDWAIVPPSVDGEKESSYHIYALRIKDFTEEQRDRMIDEIAKSEVA
                     VNVHFIPMPMLSFFKSMGYDIKDYPQAYQNFKSEISLPIYPQLDSEKLNFIIETVKAAY
                     ATVITENR"
     CDS             9923..10384
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Bac_transf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1146:sugar transferase (Score: 167.6; E-value:
                     8.7e-51)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_10"
                     /sec_met_domain="Bac_transf (E-value: 5.8e-44, bitscore:
                     139.1, seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRYGGDFYVYKFRSMRVGADKKGLITVGGRDPRITRTGYLIRKY
                     KLDELPQLFNVLKGDMSLVGPRPEVRKYVDLYTDEQKKVLSVRPGITDYASIEYVDENM
                     ILGEASDPDRAYIEQIMPDKIRYNMKYICNRSVKEYFKIIFLTFWSIIR"
ORIGIN
        1 ctattataat tattcctgta caaattttga gtgttgttat attaggacgg ttcttcatgc
       61 gtacatctca agaagttatt aaacgagtac tttcttttat attgtttttt agtttatttc
      121 tttttattat tctgtttata gctaaaagat acatcttaac atattattca ttctctttag
      181 tatctgatgt tttatggagc tttagtttag ttctattttc atctttattt gctaatttat
      241 cagtttttat aggagataat attatgatct ctaactcatt ggagaagcaa ttgataaaaa
      301 gttctatata tagttctttg tttgtatttc cactactgat tataacgctt tgttttgtgg
      361 ataattcttt atttacacta tctgtattct ttttgtttca taaaatattg gaatttctgt
      421 tgagagtata ttattcatgg aattatataa attaaaaaat aggaataata ttattctttt
      481 actgaaaatt cagtatctga attttgcatt gtcaatacta ctatttatag tgaatttgat
      541 aagtggagct acaattaatt accttttctt ttcatattat ctgctctttt cttttttgta
      601 tataactgtt gttagtttaa aagtattttc attggctagt gcttttaatc tgtttctttt
      661 tggatatttt atgtttcaaa tatctgcttt gtttgtgtca ttagatacac ttttagaaag
      721 aaaacttatg gataatttgt tccttttttc cgaggagcaa ataaataata ctttatgtgc
      781 taattctatt attttgaatg ctatgttttt aggatgtttg atgtctataa tttatttacc
      841 aataaaaaca aacataaata aagctaattt gatatactct gaacgattac agaattgggg
      901 atatttgctt ttttgggctg ccttaccatt tactcttttg aaattttatc ttgaaataaa
      961 attagtttta acagaaggat attatgcata ttatacttca tctttatcta taccctttct
     1021 aatttcaatt tctaggttta tttttgaaat tggttttttt ctttttctaa catctttacc
     1081 gccgaaaaaa aagtttttaa ctgtatcaaa ggtgtatata ttagtaatgt gtttattctt
     1141 tttaattgga gttcgaaatc gtgtaatcct ttcgttttta tttgttttat ggttttatta
     1201 tagattttat agtaaaaaat ctcctaaaat attgtttttg ttgattattt caattagttc
     1261 tgttgcactt ttgcttttgg tacagttggt tagacaagct ggtgtttttc ttttatcaga
     1321 tgacagatct atttttagtt atttctttta tgcacaatct actaattttt acatattacc
     1381 acttcttcag tattatgact tacacacaga agttcctttt gtttttgctc ctttctttaa
     1441 tttagatact agttattatg acccaaatgg aattaataat ttattaggaa atgctattgc
     1501 ttttcgtatc tctcctgatg aatttagaga agggcatggg cttggttcaa gttttatagc
     1561 ggaattgtat gatctaggaa ttgtttttat gtctatttta tctattggtt taggttttgt
     1621 gatggggtgg ttcgagagaa atgttaaaaa taatagagct cttcttgcta tttcatttta
     1681 tgctatcaca aattgtatat atatatcaag aagtagtctt tttagaaatg tatatatgtt
     1741 tccattactt ataatattgg tttttattgc attaaaaata agatatccct ttaaaatgaa
     1801 aaaaaatgaa tatcctacac gtctctgata tagatgttag ttcatgtggg ggtggaatga
     1861 atactgtcat ccctgaactt attatgcggc aactcttgta tgatagtaca cttaatgaga
     1921 cgctgtttat aacccgaaaa aagtataaaa ttgcaaaaca gattccatac ttcatttgct
     1981 tcatggaagg gaactttctt aagtatttgc agaaatccga tttgctggta tttcattctg
     2041 tatataattt aaaatttata ttactctatt ttttttgcaa gaagaataag ctgccttatt
     2101 taattgttag tcatggtgga ttatcaaaag ttgcattgaa aaaaggaata ataaaaaaga
     2161 agctatttaa gttcttgttt ttgaatcgtt ttgtaaagga tgctactgtg ctttgtttta
     2221 catcattaga ggagcaatta agttctgtat atacagataa aaaatatata atagttccta
     2281 acccaattca aatttcagat tattcttatc ggttagacgt gagcaataat gatgaagtta
     2341 aaatgatatt tctttcaaaa atagactttt attataaagg gcttgatgtt ttatttgatg
     2401 cattaaacat aataaaagaa gatatagtta atgcaaatgt ttttttatcc ttttatggtt
     2461 atggtaagaa taaagaagta gatgtcgaaa atatcaatag tgccgaaaaa gatatattaa
     2521 aattgatttt acgtattaaa gaattgaata ttggtgaaag aataaaatat tgtggccctg
     2581 tctttggaca tcagaaaatg gaagttttga agaacagtga tatttatgta ttaacatcta
     2641 gatcagaggc tatgccttta agtattagtg aagcattatc tgttggtact ccatgtttgg
     2701 taactcatgg tactaatatg tccaatttga tagaacagta taaggctggt tggtcttctt
     2761 ctttaaataa agaagatttg gcttttaata ttttaaaagc tataaaggaa tataaagatt
     2821 ctcccgtcac ttttcgtaag tcagcaaggg gactttatga atataatagc tctattgatg
     2881 taggaaaggt atcaatcgat caatataaga ctatattaga ggaaaaataa tgttgtacta
     2941 ttttcggatt tttatttcat atttattata tgaatttgga gttagaagaa aagatataat
     3001 tatcttttct ggttataaaa acttgaagta taattttaat tctagatatt tatttgaatt
     3061 tttcttagaa aaaaaatcaa atttaaaatg tttttttgtt atagatgatg ataatttaag
     3121 acggcgattg aatgaaatcg ttggtgatta ttttgttaca acaaatagct ggaaagattt
     3181 aaaacttatc ttttcagctg gtacatggat aacttctgga ggattgccaa ttaggatacc
     3241 atatgtaaat aggaatcgcg ttgttgtaaa tttgtggcat gggcttcctt ttaaaggaat
     3301 aggcttactt aacaatgaaa atacatgttt gcaaaacttg ttgatctatt gggtttattc
     3361 aaagtatgac ttattttctt ccacatcaga attatttcaa caaatatttg ctcgtagttt
     3421 ttcgattaat tctaaatctg taaaaatatt ggggcaacct tggaatgatc aattgtggaa
     3481 tgaaaatgat aaatatgagg ttttaggtga tatttatgga gataatttac catcttttta
     3541 taaggtgttt ttgtatgcac cgacttggag aagcggacgt tgtacatctt tctttccatt
     3601 taaggatttt tcaaaaaata ggctggaatc ttttctagaa aaatatcaat tactaatttg
     3661 tctaaggaca catcagttgg aagctaatag agtaaaggat tatgtttcgt gtaaaagggt
     3721 tctgttgctt aatgaagata gggttactga tattatgtca atattgaata tttttgatgg
     3781 attgatatct gattactctg gtattatctt tgattatttg ctattggacc gcccaattat
     3841 attacttcct tatgataaag aagaatatac ttctgaacgt agtgtgaatt ttaacattga
     3901 ttcttttgag tttgcccctc ctccttataa catagatagt tttttcagtt tgttgcaaaa
     3961 agctgtatgt tgtaaatgta tatctcagaa gcaattacga ttcaaaaatg tagttcacta
     4021 ttatatagat aataatagtt gtcaaagaca ttatgaagaa ataatgaaac ttataaaaat
     4081 gaaaaataac aaacaagtaa agaaatggat atagaaaaga agaaaactgt gtatgttggg
     4141 atgagtgctg acattattca tccaggtcac ttaaatatta tttcagaagc ccagagatta
     4201 ggtaaggtaa cggtcggagt tttaacagat gctgcgatag ctagttacaa acgattacct
     4261 tatttgaatt atgagcagcg ctctttaatt gttaaaaata ttaagggagt ggatgaggtt
     4321 ataccacaga caacgcttga ttacgtacct aacttgaaat tgttaaagcc tgactttgtt
     4381 gttcatggcg atgattggaa agagggtata caaaaggaaa ctaggcaaaa agttattgat
     4441 acaattgcaa aatggggagg aaaggtcatt gatattcctt atactaaagg aatatcttct
     4501 actcaactta atgaaaagct aaaggaaatt ggtacaactc ctgaagttcg tttaaagagg
     4561 ttgagacgtc ttattgaagc taagtctgtt gtacgtattt gtgaatctca tagtgggctg
     4621 acagggctga taattgagaa cacagtcgtt gaggtaaatg gagtaaaacg cgagttcgat
     4681 ggtatgtggt caagtagtct gactgattct acatctaagg gtaagcctga tatagaggct
     4741 gtagatttaa ctactcgtct tcatgatcta aatgatgctt tagagtgtac aactaagcct
     4801 attatatttg atggcgatac gggggggaaa atagagcatt ttgtattcac tgtgcgtaca
     4861 ttagagcgtt taggtgtttc agctgttata atagaagata aagttgggtt gaagaaaaat
     4921 tcgttatttg gtactgatgc tgttcaactt caagatacaa tagaaggttt ttctgagaag
     4981 ataaaagctg gaaagctggc tcaaataact actgatttta tgatcattgc acgcattgaa
     5041 agttttattg cgggtaaagg gcttgaggat gctatagaga gagctttggc gtatgtagaa
     5101 gcaggagcag atggtataat gattcatagt aaagataagt caggggaaga tattaaaaaa
     5161 ttttgttatg catttaggca actgaataaa tctataccaa ttgtagtcgt gcctacaact
     5221 tataatcata ttacggaaac agaattggct tcttggggag taaatgttat tatttatgct
     5281 aatcatctgc ttcggagtgc ttatcctgca atgcttaata ctgctaaaat tattttggct
     5341 aatgaacgtt cgtttgaagc aaatgattta tgtatgtctg taagggaaat attagaatta
     5401 atacctggta ctaaatagtt ggaaattatg ttatcaccta agtttttcgt agaaacgttg
     5461 caaacatatt ctatggattt ttttactgga gttcctgact ctttattgaa gaatatgtgt
     5521 gcttatatta cagatcatat agaatctcaa aataatatta ttgcagtgaa cgaaggaact
     5581 gcgcttggac tagctgccgg atattatatt gctacagggt gtattcctat tgtgtatatg
     5641 caaaattcag gtattggtaa taccgtaaac cctttgttgt ctttgacgga taaagtcgtt
     5701 tataacattc ctgtattgtt gttgataggg tggcgtggtg agcctggtat aaaagatgaa
     5761 ccacaacaca ttaaacaagg catgattact attcctcttt tggatactct tggtataaag
     5821 aatcaaattc ttaataaaga tcctaatatg gcaaaaagtc aaataaatga tgcaatagaa
     5881 tatatgagaa tgacaaaaga ggctttcgct tttgtcattc aaaaagatac ttttgaagaa
     5941 tataagcttc aaaatacaga ggatagtaaa tttgatttgg atcgagaaga agcaattaaa
     6001 atagtttgta attctttaga taaaggtagt gttatagttt caactactgg gatgatttct
     6061 agggaattat ttgaataccg ggaatctatt gatgcaaatc atgaaacgga ttttttaaca
     6121 gtagggtcaa tggggcatgc atcacagata gctttaggta tagctctccg aagaaagaac
     6181 aaaaaagtgt attgtttcga tggtgatggt gctgtactta tgcatatggg agcattaact
     6241 accataggaa ctagtagagc tgtgaattat attcatatcg tgtttaataa tggtgcgcat
     6301 gactctgttg gtgggcaacc aacagtggga ttaaaggtca atctctctaa aattgcttct
     6361 gcttgtggtt ataataatgt tatatctgta gatagtaaag ctactttaaa agaaagtttg
     6421 gataggttta aaagtataaa tggacctgta ttattggagg taaaagtgag aaaaggggca
     6481 agaaaagatt tgggacgtcc tactttgact cctgttaaaa ataaggaatt attaatgaac
     6541 tttttagaag aagcagatga atcagataaa tcagataatg tgtttaaata atgatccatt
     6601 tgaatattta cagagtaatt tatctagata tagctctcgg aaattattcc tcgttagggg
     6661 caaaaagtct tatgaattat gtggagcaaa aagagttgtt gaagatgtta tttctaattt
     6721 aaagtgtggg tttgttgaat attttgattt ttcagaaaat cctaagtatg aggatttgga
     6781 gagagggctg aaattgctgg aattaagtgg ggcggattta atagtagcca taggtggtgg
     6841 aagtgtttta gatatggcta aattaatccg cttttttcat tcttattcag gagatatatt
     6901 aaatgagaaa tttgttaaaa atagagattt attaccttta ttcgcaattc caactacagc
     6961 aggaactggt agtgaagtga ctcattttgc tgttttatat aaggataatt tgaaatattc
     7021 ggtttctcat aaggatatgt tgcctgatag ggctataatt tgtcctcagt ttacgtataa
     7081 aaatgcaaga tatttgacag cgtgtaccgg ctttgatgct ttatcacaag ctattgaagc
     7141 ttattggaat gtttactcaa ttgaagaatc tgataattac tctattaaag ctataaagtt
     7201 aatatgggat aaccttcctt tagtgattga ttcctcaaca aatgaattaa gagataagat
     7261 agcagaaggt gcttattggg ctggtaaggc tattaatata acaaaaacga cagcgcctca
     7321 tgctttctca tatcctttta cgataaacta tggctaccct catggacatg cagtagcatt
     7381 aacatttcct ttttttatga gatataatta tgcagaatta gaaaataagt tgcatccttt
     7441 attgaatagt aaaagtcatt gtaaaaaaat ggagcaatta tataacatgc tgggatcaac
     7501 ttttgatatg atttatgatg atatgtataa ttatttagaa agaataggct tagctattaa
     7561 tattagagga aggaattttg ataaaaatct tattttacat ggtataaatg cttctcgttt
     7621 atctaataat ccttgtgtat tatctcaagc agatgtagat tttatagtgg atgaatttgt
     7681 tgaaaatgga aagttgtaat atgaagctct gtgtgattat gtctatttat aaaaatgaca
     7741 atctgctagc tgtaactcag tctatagaaa gcattttaag gcaggcttat gaaaaaatag
     7801 aattttacat acaattagat ggggaaatac gttcggatgt tcttcaatat ttacggggac
     7861 tgtgtattca agatatacgg gtaaaaatat taaatcggac attgaatagg ggattagctt
     7921 attcactaaa tgaattattg aatatcgttc ttacaaaaga atacgaatat attgctcgta
     7981 tggatgctga tgatatttcc atgccggaac gttttgtgaa gcagatcgca tttatgaatt
     8041 cacatccgga tattgattgc cttggtactt gggcaataga aattgatgat gacggaaaag
     8101 aatattttcg aaaaaaaatg ccgataactc atgaagaatg tttggaactg tttaaaaagc
     8161 gggattgtat gattcatcct actgtgatgt ttcgacgttc atattttgag aaagctggtt
     8221 tatatcccga agacacctac tttggagaag atactatgat gtgggctaaa ggttttaaaa
     8281 gtggatgtaa atttgccaat gtacccgaat atctgtttaa gtttagattg gattcaaact
     8341 tctttgaaag aaggcggggg tggaaacatg caaaatctat ttatacttta cgtcatcgtg
     8401 ttaatagaat gttagggttc ggatggaagg aagattgtta tgcattgcta tatgctatgg
     8461 ccaaattaat gcctaaatct attcttgaca taatctataa aacagtacgt tgattttact
     8521 tttcttataa aacataaact catgaaaata cctttttcac caccttatat tgacgaggcg
     8581 gtcatcaacg aagtcgttga ttcgttacgt tccggttgga tcacatccgg tccgaaagtg
     8641 aaggctttgg aggaagaaat taaatctttc tcaggagcaa aagaagtgct ttgtgtcaat
     8701 tcctggacat caggagctat tatgatgttg cgttggctgg gagtgaagga gggcgatgaa
     8761 gtgattgttc ctgcctatac ttatagtgca acggcattgg cagtgctcca tgccggagcc
     8821 aaaccggtaa tggtggattc cggaactgat tttaatattt cggtggaggc tgttcgtaaa
     8881 gctattactc ctaaaacaaa ggcgattata cccgtagata ttgctggttt tccctgcgat
     8941 tatgaaagaa tcatggcact ggtgcaggaa ccagaaatgg taaaactgtt ccgttcggaa
     9001 tctcctgtgc aagaaaaatt gggacgcatc ttggtgatga atgatgctgc ccactctttg
     9061 ggagcacgtt acagtagccg tcagcgtacc ggttgtgaaa ctgatgtggc tatcttttca
     9121 cttcatgccg tgaaaaatgt gactactgcc gaaggtgggg ccatttgcct gaatctgcct
     9181 aagccgttcg ataatacgga gttgtataaa gagctacgga tgacaagctt gaactgccag
     9241 accaaggatg ctttttcgaa atctaaagcc ggaggatggc gttatgatat tgtcggtttc
     9301 gggatgaaaa tcaatatggc cgatgtaaat gccgccatag gactggcaca gatacgagaa
     9361 tatccggaat tgctgaaaga acgaaagcgg gtgtttaatg cttatagcga tgctttttcg
     9421 gcttgtgact gggccatcgt tccgccttct gtggatgggg aaaaggaaag ctcttatcac
     9481 atttatgctt tgcgtattaa ggactttacc gaagaacaac gcgaccggat gattgatgaa
     9541 atcgctaaaa gtgaagtggc tgtcaatgtg cactttatac cgatgccgat gttgtcgttc
     9601 ttcaaatcga tgggatatga tataaaggat tatccacagg cttatcagaa ctttaagagc
     9661 gagatatcat tgccgatata tccccaattg gatagtgaaa aattgaattt cattattgaa
     9721 actgtaaagg cggcctatgc gaccgtaatt acagaaaacc gatagtatat ttacaaacac
     9781 taaatagata agtttcttga tccgtttttt tgatatcgtt ttttcccttt tgggaattct
     9841 tctgctttct cccgtttttc ttcttcttta tatagccatt tgtctcgaaa gtaaaggagg
     9901 tggtttctat aaacagctcc gtgtgggaag gtacggaggg gatttttatg tttataaatt
     9961 tcgttcgatg cgtgtagggg ctgataaaaa ggggttgata acggtaggag ggagagatcc
    10021 gagaataact cgtaccggat acctgatccg gaagtataaa ttggatgaat tgcctcagtt
    10081 gtttaacgta ctgaaaggag atatgagtct ggtggggccc cgtcctgagg ttcgtaagta
    10141 tgtggattta tataccgatg aacaaaagaa agtattgagt gtacgtccgg ggattacgga
    10201 ttatgcttct attgagtatg tagatgaaaa tatgattctt ggagaggctt cggatcctga
    10261 cagagcatat atagaacaga ttatgcccga taagatacgg tataatatga aatatatctg
    10321 taatcgttcg gtgaaggaat attttaaaat tatatttctg acattttgga gcatcattcg
    10381 ttaggtatgt ttttaaggaa actgggggaa gttcttcttt ttgttttcgt accctattat
    10441 gtgagaaaga ataaggagta gacggaagtt tcgaagagaa gttaattcaa taaaaaagaa
    10501 aggatcggca attgccgatc
//
