LOCUS       gnlProkkaLGPHAHFH_214   4997 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LGPHAHFH_214.
ACCESSION   gnlProkkaLGPHAHFH_214
VERSION     gnlProkkaLGPHAHFH_214
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 10:18:48
            Original ID  :: gnl|Prokka|LGPHAHFH_214
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4997
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4997
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1:3148]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2..3148
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..4997
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..4997
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(2..1090)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.2;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg214_1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 3.9e-21, bitscore:
                     63.8, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.4e-21, bitscore:
                     64.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPI"
     CDS             complement(1107..2408)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 208.9;
                     E-value: 1.5e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg214_2"
                     /sec_met_domain="CTP_transf_like (E-value: 7.6e-14,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 7.9e-122, bitscore:
                     394.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 8.9e-64, bitscore:
                     203.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKIILENERALEVRELCMPIKEILELIPGTK"
     CDS             complement(2429..3148)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 54.5; E-value:
                     1.6e-16)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg214_3"
                     /sec_met_domain="NTP_transf_3 (E-value: 6.3e-17, bitscore:
                     50.8, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CDIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             complement(3212..4360)
                     /locus_tag="ctg214_4"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVFFGKSLLASLRKELKNKEIEQDK"
     CDS             complement(4371..4997)
                     /locus_tag="ctg214_5"
                     /transl_table=11
                     /translation="MMTSREERLSDLVNKAGGPTSLAYLRGAKLTRVASAGEKKRMGDV
                     IRLMSRQLGEAMIDSLGIGVEDTFTVGIDLEKALTNPKGSADLVLREGDVVFIPKNTNT
                     VTINGAVMVPNTVSYMKGKDVDYYLNQAGGYSDNAKKSKKFIVYMNGQVTKVKGSGKKQ
                     IEPGCEIIVPGKAKKKGNIANILGYATSFSSLGMMIASIANLIKK"
ORIGIN
        1 ctataggagt agtcgtggga cgtcccaaat tctcccgaga atctatttta acctttattt
       61 ccaacaaaac aggaccacat aactttggaa gctgcttcat tgcttcttca atttcaactt
      121 ttgtacaaac agtataagta tgcttatatc cgctcccccg gacaatagcc ggaatatcta
      181 aactaaatcc taaagtaggc tgtcctccta cagactcgtg agcaccattg ttaaacaaaa
      241 tatgataata gtttttagga gataaatcgc caatgttact aattgcccct aaatgcataa
      301 taaatgctcc atcaccatcc aagcaataaa caggtctatc ttgctttgct atagcaatac
      361 ccaaagagat tgatgaacta tgtcccatag agcctaccgt gagaaaatca tgttcatgac
      421 cttgctcttt catttctcga tattcaaata actcacgaga aagcttgcca gtagtagaaa
      481 cgaccactga attttcaggc agataatcca caactatttg caaagcatcc tcacgagata
      541 aaggataatt acatccgaac tctttttgaa gtttatattt gccaaaaaca tctttccgaa
      601 taattattgc atgaggaata ttcttagttt ttgctgattg tatgatatca tggagctgaa
      661 taaatgcatc attctcattt gaatcaagaa ttatataagg aatccgcatt gctttcaaca
      721 aatctaaagt tacctcaccc tgttttttat gctgaggttc atcttttgtt cccggttcac
      781 cacgccagcc aatcatcaaa agcattggaa aactgtatac ttgttcatct gcaagagaca
      841 gcagaggatt aacagtatta cccaagccgg aattttgcat ataaaccaca ggaaccttac
      901 ctgatgccat ataataacct gaagcaattc ctacagccgc accttcatta gcagctatga
      961 tatgtttctc acgtgaagta tggtctgtga tataggcaca aatatttttt agtaatgagt
     1021 ctggaactcc tgtaaaaaaa tcaacgtcat gactcagaaa cgtttcataa actttttcta
     1081 cgcttaacat aatgatattc ctctttttat ttagtacctg gaatcagttc caatatttct
     1141 tttatgggca tacacagttc gcgcacctct aaagcacgtt cattctctaa tattatcttt
     1201 gcgacattca tcatagcagg ataagcggca cgaagcatat gattagcata aataattata
     1261 ttcacacccc aatcacacaa ttcagactca taaatatgat catatgtagt aggcacaacc
     1321 acgataggta catgagcata ctgttttcga aacgccaaac aaaattcttt tatatcttca
     1381 cccgacttat ttttgctatg tatcataata ccgtccgctc ccgcttggac atatgcaaaa
     1441 gctctctcta aagcatcact taccggcttt cccgctataa ggctctcaat acgagcgata
     1501 atcataaaat catcagtaat ctgagatgcc tttcctgctt tgatcttatt acagaaacct
     1561 tcgattgtat cttgagtttg aataacatct gtaccaaaca atgaattctt ttttaatcca
     1621 actttatctt caattattat agctgaaatt ccatgacgtt ctaaagtgcg tactgtaaat
     1681 acgaaatgtt caattttacc acctgtatct ccatcaaaaa taataggttt agtagtacac
     1741 tccagaatat tattcaaatc ttgcaatcgg gtagttaaat caaccgcctc aatatcaggt
     1801 ttacctttac tggttgaatc cgtaaggcta ctagaccaca ttccgtcaaa tacttccctc
     1861 ttatcccctt ttaatatttc ctgattttca attatcaagc cacatagtcc atcatgagct
     1921 tccaaaatac gaactacggg tttggcattt atcaaacgac gaagtgattt taaacgtaca
     1981 tcaggggttg tacctatagc cttaatatct ttatccaaag aagatgaatt aattcccaaa
     2041 gtatatggaa tttcgataac ctttcctccc tgttcattca tcacttcaaa tacgcgcaca
     2101 cgttcttcac gtaaaggccc ggttttccag tcgtcaccat gaattatata gtcaggttta
     2161 atgcgtttga gattctcaac atagctccat tcttcttgag gaacaacttt acatacgcct
     2221 ttaatattct gaactacctc ttttcgttgt tcataggtca gataaggaag gcgtttatgc
     2281 tccgcaatag ctttatctgt aagaagacca attataacat caccgtattt agtagcctca
     2341 ttaataatgc ggataagtcc tggatgcata atatccgcag tcatcccaat ataaactgtc
     2401 ttactcataa tttgatatat tattttaatt aacaatacgg aacaatatat ttctctgcat
     2461 attccaaatc tgatatgtca tcgatttcat accatttcag cccttctact ttatgcacat
     2521 aaacaggaga ttgagaacaa gatattcgta gtaattcata ctcatatccc aaattgggtt
     2581 gttcatcaac aatactcgca taatcagcac acattatttt gtaaaaggaa ccggatagtt
     2641 tatggatgcc gaccaattcg cctttagcgt ttagtttatt cttattgaca gaacatgaag
     2701 aaaggcgaaa attatcatca tgttccacat aatactgatc ttgaaacttt gtcactggag
     2761 ttattagcat tgcatctgcc gcaggacact ccaataagct cattattgct tgtttctcaa
     2821 aaatcaaatc tgactctaac aataaaaaat catcattgcc cagaatctcc cgcgtattat
     2881 ataaagtata catactattt gtttcagcat aacgaggact aaaacaggtt tcaagcatag
     2941 gatagtctgt cttcaattct tcataaactt cttgtttata tcctgtaccg attacaattc
     3001 gctcaatgtc acatgataac aaagtatcaa tagaacgaac tatcattgga atacctccca
     3061 ctttgacgaa ccctttaggt atcaattctg tatattggcc aaaacgggtt cccatgcccg
     3121 cagccattat catagctgta cgtatcattc gtttaataat atagtaagtg aatttaattg
     3181 atgtaagaat gttgtaaacg acgttttagc atcatttatc ctgttctatc tccttatttt
     3241 tcagttcttt tctcaagcta gccagcagac ttttgccaaa aaacacccac acgagagtac
     3301 cagatacgga caggaacaca aataataaaa tataaatttt gagtcccata cctgaaggtt
     3361 tcaaaggtac aacggcaggc tcaactactg caaagactgg cttttcctcc tgtactttgg
     3421 ctctggatac ctgcaactga ttagcaacct gactatatat ctgataagcc aaactcatgt
     3481 cgttctgtaa acgctcctgc tcagcacgta cactttgaag aaccacatta tcatgggcgt
     3541 ctacataatc cgcatatttt ctttgagcag cataatattc ctgctgacgt tctttaaaca
     3601 accgttccaa atacgcacag tcttctttta cttttgaagt tcgataccca ataatatatt
     3661 cctgtaattt atgaacgaca gaatctgcta taaccgcagt gatctgcgga ttttgtaagg
     3721 tgaccgtaat gctcgttatg gcggttttct tatcaatgga tgcactaatc ttctttttaa
     3781 gaaaattaat cttctcattt acttctttcg tcaattcgat agttccttgc cgccctccac
     3841 tggcaggaac cgtatcttct ccgaataatg atttaactcc tcctattact atgcccggaa
     3901 aacctataag ataatcccac caaggagatg actcttcatc gagataagac cccaaagtca
     3961 ttttatcatc ctttttagaa acggagactt ccatttctaa aagttccaat aaaaaaggag
     4021 ttgaagaaac aatatctgct gaaagagaag cgttcaaggc atctgtgctt tcccctatta
     4081 gagccccatc tcccaaaaac gaggcagcaa gtccggctaa accattactt cccttcgcat
     4141 tacccatttc aggagaaagg gtaaccttta ctgtatattg cttgggaatg ctcaatgcca
     4201 ccactatagc aattattact cccactccag cagctttgca tagtactcca cgaacagtaa
     4261 taatcttata aaaaatagcc atcaagtcta tttccatttc atcatctttc cttttatcca
     4321 cttcagaaaa cggttcttga taagattgct tttcaatcat aataggtcat ttatttcttt
     4381 atcaaattag caatagaagc aatcatcatt cccaaagaac tgaaggaagt agcataacct
     4441 aaaatattag ctatgttccc tttcttctta gccttaccag gcacaataat ctcacacccc
     4501 ggctcaatct gtttcttacc actaccctta accttcgtca cctgaccatt catgtaaacg
     4561 atgaatttct tactcttctt tgcattatca gaataaccac cggcctgatt caggtaataa
     4621 tccacatcct ttcccttcat ataagaaacc gtattgggaa ccatgacagc accattgata
     4681 gttacagtat tagtattctt aggtataaag accacatcac cttcacgtag gacaaggtcg
     4741 gcactaccct taggattagt caaagccttc tccagatcaa tacctaccgt aaaggtatcc
     4801 tcaacaccaa tacccaaaga gtcaatcatg gcctcaccca attgcctgct catcaggcga
     4861 atcacatcac ccatacgttt cttctcaccc gcacttgcca cacgggtcag ctttgcacca
     4921 cgaagatagg caagactcgt agggccacct gctttattca ccagatcgga aagacgttcc
     4981 tcacggctgg tcatggc
//
