LOCUS       gnlProkkaAKPCACCP_58    7371 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AKPCACCP_58.
ACCESSION   gnlProkkaAKPCACCP_58
VERSION     gnlProkkaAKPCACCP_58
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 11:15:45
            Original ID  :: gnl|Prokka|AKPCACCP_58
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7371
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..7371
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1439:6840]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1440..6840
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..7371
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..7371
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             122..1426
                     /locus_tag="ctg58_1"
                     /transl_table=11
                     /translation="MIYMFTRMIRSLLSRSPLYVLALYASVLIFLVYTCAYAYRKPFTA
                     AIYEGEILWGFDVKILYVLSEIIGYALSKFIGVRILPSMKAGHRIYYIIGLLTFSEVAL
                     LGFALLPVPLKVCSIFLSGLPLGMIWGVIFSYIEGRRISEILNVGLSVALIVSSGLVKT
                     LGQFVMDNLHVSEYWMPFTTGLLVYPVMLLCSWLLNQIPAPNEQDIIQRTKRAPMDGKD
                     RRKFLRQFFWGICMLVVFYGALTVFRELRDSFAADIWKELHIEGAMIFTQTEVPIAVFV
                     LVLMFLIVFVRNNRLALNIIYCIAVTGGSLMVFSTLLYVYGFLSPIWWMILSGLGLYMG
                     YIPFTYLIERLIASLRVVSTAVFIIYLADSFGYLGTTGVFMVKNFVSADISWTVMLMRT
                     ALFSGFVSVLSIFAIYCYFKQQLNSLILIPSEIHD"
     CDS             1440..2138
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg58_2"
                     /sec_met_domain="NTP_transf_3 (E-value: 8e-15, bitscore:
                     44.4, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAGLGTRFGHYTELVPKGFVEVGGKPMIIRSIETLLSCGIERII
                     LGTGYKKEAYEALQADFPQIETCFSPRYADTNSMYTLYNTRDVIGDDSFLLLESDLVFE
                     RKAILSLLDDEFPDVMLVSSLTKFQDQYYVEYDRNHILTSCSVDKDALEAKGELVGIHK
                     LSNTFYRRMCADYATILESQPKLGYEYELLRMSRSVSPVRVLRVEGLKWYEIDDEADLS
                     YAEEHIIRYC"
     CDS             2158..3459
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 214.1;
                     E-value: 3.9e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg58_3"
                     /sec_met_domain="CTP_transf_like (E-value: 1.8e-13,
                     bitscore: 39.9, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 6.5e-123, bitscore:
                     398.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 3.2e-65, bitscore:
                     208.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKIYVGMTADIMHPGLIHIIHEATKYGDVIVGLLTDKAIAEHK
                     RLPYLTYDQRKEVVENIKGVCEVVPQEDWSYVPNLEKLKPDYIIHGDDWKTGPLREVRE
                     QVFEVMNAQGGKVIEIPYTRGINSSSLDKDIKAIGTTPDVRLKSLRRLIQAKPVVRILE
                     AHDGLCGLIIENLEVQKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAVIIEDKVGLKKNSLFGTDAIQTQDS
                     IEGFCDKIRAGKNAQVTGDFMIIARIESLIAGKPMSDALERAYAYVQAGADGIMIHSKD
                     KSGEDIREFCRTFRKEYAHVPIVVVPTTYDHVHESELHEWGANVVIYANHLLRAAYPAM
                     MNVARTILENERAEEVRPLCMPIKEILELIPGTK"
     CDS             3471..4607
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 71.8;
                     E-value: 7.9e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg58_4"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.1e-22, bitscore:
                     69.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.8e-21, bitscore:
                     64.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSVEKIYDTFLHHGVDFFTGVPDSLLKNICAYITDHAPRGKHII
                     AANEGSAVGIACGYYMASGNVPLVYMQNSGLGNTVNPLLSLADEKVYSLPLLLLVGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMKIPFIILDTDEDEALAQIHDAVVSAKSRSIPHAIV
                     IRKDTFGKYKLRQEALNDYPLSREEALMQVVDHLGDNDIVVSTTGKLSRELFEYRESKG
                     QGHARDFLTVGSMGHSSSIALGVALEKPDRRVYCLDGDGAFIMHMGAVSNIGDLSPKNY
                     RHVLFNNGAHESVGGQPTLGFRLDIASIAKGCGYAHVLTASDKEGLSCALEKLSGLSGP
                     VLLEIKVRIDSRDDLGRPTTTPVENKEHFMAFLKDTHS"
     CDS             4604..5728
                     /NRPS_PKS="Domain: Aminotran_5 (30-301). E-value: 6.1e-34.
                     Score: 109.3. Matches aSDomain:
                     nrpspksdomains_ctg58_5_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 80.4; E-value:
                     2e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg58_5"
                     /sec_met_domain="Aminotran_5 (E-value: 5.3e-32, bitscore:
                     100.0, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIERKILLNPGPATTTDTVKLAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGDLSKHTAVLFCGSGTINIDICLNSLLPADKKVLVVNNGAYSTRAVEVCEYY
                     GLPHIDLKFSVYELPDLSVIEKTLSDNPDIALVYTTHHETGTGILNPIREIGKIAHSHG
                     AVFVVDTTSSLGMIPFDIGKDNVDFCMASAQKGLQAMTGLSFIIGDESLIRASRDYPKR
                     SYYCNLYLQYDYFEKTGEMHFTPPVQTVYAARQALDEYFAVGEEAKFARHKRVFEAIHK
                     GLQELGLQYAIKREWQSGLVVSVLYPDDPLWDFDKVHDYCYERGFTIYPGKISTTNTFR
                     LCALGEIDVEDIERFFEVMREAISFLKISFKNIV"
     aSDomain        4694..5506
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg58_5_Aminotran_5.1"
                     /evalue="6.10E-34"
                     /label="ctg58_5_Aminotran_5.1"
                     /locus_tag="ctg58_5"
                     /protein_end="301"
                     /protein_start="30"
                     /score="109.3"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGDLSKHTAVLFCGSGTINIDICL
                     NSLLPADKKVLVVNNGAYSTRAVEVCEYYGLPHIDLKFSVYELPDLSVIEKTLSDNPDI
                     ALVYTTHHETGTGILNPIREIGKIAHSHGAVFVVDTTSSLGMIPFDIGKDNVDFCMASA
                     QKGLQAMTGLSFIIGDESLIRASRDYPKRSYYCNLYLQYDYFEKTGEMHFTPPVQTVYA
                     ARQALDEYFAVGEEAKFARHKRVFEAIHKGLQELGLQYAIKREWQSGLV"
     CDS             5731..6840
                     /NRPS_PKS="Domain: Aminotran_1_2 (37-163). E-value:
                     1.2e-06. Score: 19.8. Matches aSDomain:
                     nrpspksdomains_ctg58_6_Aminotran_1_2.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     280.3; E-value: 4.2e-85)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg58_6"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 8.5e-96,
                     bitscore: 310.1, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.5e-07, bitscore:
                     19.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEENQITVTSPLLPSLDDFLPYLEDIWKRKWITNNGYYHQELEKA
                     LCQYLKVPYISLFTNGTLPLICSLQALRITGEVITTPYSFVATTHALWWNGIKPVFVDI
                     DPKTCNIDPNKIEAAITPKTTAIMPVHVYGNPCDFIAIQDIADKYGLKVIYDAAHAFGV
                     EVDGKSLLEFGDMSTLSFHATKVYNTIEGGALVCHDRQIKERVDFLKNFGFAGETQIVA
                     PGINGKIDEIRSAYGLLNLKAVDSAIEYRHQISKRYREGLGGIDGISYMPEMHNIRHNY
                     SYFPIFIDSVKYGITRDELYEKMKRNGVCGRRYFYPLITNFSTYCGLDSAQISNLPVAN
                     RIANSVICLPLHTGLTSIDVERIIELLKK"
     aSDomain        5842..6219
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg58_6_Aminotran_1_2.1"
                     /evalue="1.20E-06"
                     /label="ctg58_6_Aminotran_1_2.1"
                     /locus_tag="ctg58_6"
                     /protein_end="163"
                     /protein_start="37"
                     /score="19.8"
                     /tool="antismash"
                     /translation="YHQELEKALCQYLKVPYISLFTNGTLPLICSLQALRITGEVITTP
                     YSFVATTHALWWNGIKPVFVDIDPKTCNIDPNKIEAAITPKTTAIMPVHVYGNPCDFIA
                     IQDIADKYGLKVIYDAAHAFGV"
     CDS             6837..7370
                     /locus_tag="ctg58_7"
                     /transl_table=11
                     /translation="MTSFYSEKELANIGLAVYGTNVLISRKVSFYSPKNIYIGNNVRID
                     DFCILSGKILIGSNIHISAYVAIYGGYGVVLEDYVGISPRTTIYSAMDDFSGDYLVGPI
                     HDKRLTHVIGGEVRICKFAHIGANTIVYPGCSIGEGTVVGAMSMVRKSLDAWGVYIGIP
                     AKFLKNRNKNMQSLI"
ORIGIN
        1 agctaatcct tataattctt tatttatgga taaatagatt tctgagtgtt ttttatttag
       61 cgaatagaat atttttacat tcagccctgt taaatcgtaa tttgaattgt cgttacattg
      121 gatgatttat atgtttacac gaatgattcg ttcccttctt tcccgttctc ccctttacgt
      181 tttggctctc tatgccagcg ttttgatttt tctggtttat acctgtgcct atgcctaccg
      241 taagccattt accgcagcca tttatgaagg tgagattctt tggggattcg atgtcaaaat
      301 cctgtatgtc ctttctgaga ttatcggcta cgccctttcc aagttcatcg gtgttcgtat
      361 tctgccttcg atgaaagcgg gtcaccgcat ctattatata atagggctgc ttactttttc
      421 cgaagttgct ttgttgggtt ttgcacttct tccggttcct ttgaaggtgt gttctatttt
      481 tctgagcggt cttcccctgg gtatgatctg gggtgtcatt tttagctata tcgaagggcg
      541 tcgtatcagt gaaatattga atgtcgggct gagcgttgct ttgatagtct cttccggttt
      601 ggtgaaaacc ttgggacaat tcgtgatgga taatttgcat gtgtcggaat attggatgcc
      661 ttttaccacc ggtttgttgg tataccctgt tatgttgctt tgcagctggc ttctcaatca
      721 gattccggct cccaatgagc aagatatcat acagcgtacc aaacgtgctc cgatggatgg
      781 taaagacagg cgtaagtttt tgaggcaatt cttttgggga atctgcatgc tggttgtttt
      841 ttacggtgcc ctgaccgtgt tccgtgagct tcgtgactct ttcgctgccg atatttggaa
      901 ggagctccat attgagggtg caatgatctt tactcagaca gaggttccca ttgccgtttt
      961 tgtccttgta ctgatgttcc tgattgtgtt tgtccgtaat aaccgtttgg ctcttaatat
     1021 catttattgc atcgccgtca caggcggttc cttaatggtt ttttccacat tgctttatgt
     1081 gtacggtttt ctttctccta tttggtggat gattctttcc ggtcttggtc tgtatatggg
     1141 gtatattcct ttcacttacc tgatagaacg tctgattgct tcccttaggg tggttagtac
     1201 ggctgttttt attatttatt tggccgattc tttcggctat ctgggcacta cgggtgtgtt
     1261 tatggtcaag aacttcgttt ctgctgacat ttcctggact gtcatgctga tgcgtactgc
     1321 ccttttttca ggatttgttt ctgtcctgtc gatttttgcg atttactgtt atttcaagca
     1381 acaattgaat tcacttatat taattccctc tgaaattcat gattaaaaca gcaatgatca
     1441 tggctgccgg tcttggtacc cgcttcgggc attataccga gcttgtgccc aaaggttttg
     1501 tggaggttgg tggaaaacct atgattatcc gctctatcga aacccttctt tcctgcggta
     1561 tcgaacgtat catcctcggt acgggttata aaaaagaggc ttatgaagcc cttcaggcgg
     1621 atttccccca gatagagacc tgtttcagtc cccgttatgc cgatactaac agtatgtaca
     1681 ctctgtacaa tacgcgtgac gtgataggcg atgacagttt cctgctgctt gaatcggacc
     1741 ttgtttttga acgcaaggcc atcctctcgc tgctggatga cgaattcccg gatgtgatgc
     1801 ttgtctcttc tctgaccaag ttccaggatc agtattatgt ggaatatgac cgcaatcaca
     1861 tccttacttc ctgttcggta gacaaggacg cccttgaggc aaaaggcgag ctggtcggta
     1921 tccataaact ttccaatact ttctaccgcc ggatgtgcgc cgattatgcg accatcctgg
     1981 agtcccagcc taaactgggt tacgagtacg aactgctccg catgtcccgt tccgtttccc
     2041 ctgtccgtgt gctcagggtg gagggtctta aatggtatga aatcgatgat gaagccgacc
     2101 tttcgtatgc tgaggagcac atcatccgct attgttaaaa acaaatcttt tccatatatg
     2161 aacaagaaaa tctatgtcgg tatgaccgcg gatatcatgc atccggggtt gatccatatt
     2221 attcatgaag ctactaaata cggtgatgtc atcgtcggtc tgctgacgga caaggccatc
     2281 gccgaacaca aacgcctccc ttaccttacc tatgatcagc gtaaggaggt tgttgagaat
     2341 atcaaagggg tttgcgaagt tgttccccag gaggattgga gctatgttcc gaatctggaa
     2401 aaactcaagc ctgactatat catccacggc gacgactgga aaacgggccc gttgcgcgag
     2461 gtgcgcgaac aggtttttga ggtgatgaac gcccaggggg gcaaggtaat cgagatccct
     2521 tatacccggg gcatcaactc ctcctcgctc gacaaggata tcaaggcgat cgggactacc
     2581 cctgacgtac gtcttaagtc cctccgccgc ctgatccagg ccaagcctgt ggtccgtatc
     2641 ctggaggctc acgacggtct ttgcggtctg attattgaga atcttgaagt ccagaagggt
     2701 gataagcgcg aggtctttga cggcatgtgg tccagcagcc tgaccgactc cacgagtaag
     2761 ggtaaaccgg atattgaagc ggtcgacctt accacccgtt tacaggacct gaacaatatc
     2821 cttgaatgta ccaccaagcc tattattttt gatggagaca cgggtggcaa gatcgaacac
     2881 tttgtcttta ctgtgcgcac tctggaacgt cacggcattt ctgcggtaat cattgaagat
     2941 aaagtcggtc tgaagaagaa ttctcttttt ggtactgacg ctatccagac tcaggatagt
     3001 atcgagggtt tctgcgataa gatcagagca gggaagaatg cccaggtcac cggtgacttt
     3061 atgatcattg cgcgtatcga aagccttatt gccggcaaac ccatgagtga cgccctcgaa
     3121 cgtgcttatg cctatgtaca ggcgggtgcg gacggcatca tgatccacag caaggataag
     3181 tcgggtgagg atatccgtga gttctgccgg actttccgca aagaatacgc ccatgttccc
     3241 attgtcgttg ttccgacgac ttatgaccat gtgcacgaat ccgaacttca cgaatggggt
     3301 gccaacgtag tcatttacgc caaccacctt ctccgtgccg cttatccggc catgatgaac
     3361 gtggccagga ccatccttga aaacgagcgc gccgaggagg tccgtccgct ttgtatgcct
     3421 atcaaggaaa ttctggaatt gattccgggc actaaataaa tcagacggtt atggtaagtg
     3481 tagaaaagat atacgatacg ttccttcatc acggtgttga cttctttacg ggtgttcccg
     3541 attccctttt gaagaatatt tgcgcctata tcacggatca tgctccgcgt ggtaagcata
     3601 tcatcgccgc caatgaaggt tccgcggtgg gcattgcctg cggttattat atggcttctg
     3661 gcaacgttcc tttggtttat atgcagaact ccggtctggg aaatacggtg aatcccctct
     3721 tgtcccttgc ggacgagaaa gtgtacagcc ttcctcttct tttgctggtc ggctggcgcg
     3781 gtgagcccgg cacgaaagac gaaccccagc ataagaagca gggcgaggtt acccttgatc
     3841 ttctgaaagc catgaaaatt ccttttataa ttctggatac ggatgaagac gaggccctgg
     3901 cgcagatcca tgacgcggtt gtctcggcga agagccggtc gattccccat gcgattgtca
     3961 tccgtaaaga tacgtttgga aaatataaat tgcgtcagga agccttgaat gactatcctc
     4021 tgtcccgcga ggaggcgcta atgcaggttg tcgaccacct cggggacaat gacattgtgg
     4081 tttccaccac gggcaagctc tcccgtgagc ttttcgagta ccgtgaatcg aaagggcagg
     4141 ggcacgcaag ggatttccta actgtgggtt ccatgggtca cagttcttcc attgccctgg
     4201 gggttgccct tgagaagcct gaccgccgtg tctactgtct tgacggtgac ggtgccttta
     4261 tcatgcacat gggtgctgtc agcaatatcg gcgatctttc tcccaagaat tacaggcacg
     4321 tccttttcaa taacggtgcc catgaatctg tcggcggtca acccacgctc ggtttccgtc
     4381 tggatatcgc ctcgatagcg aaaggttgcg gttatgcgca tgtactgact gcctccgaca
     4441 aggaagggct ttcgtgtgcg cttgagaagc tgtccggcct gtccggcccg gttcttcttg
     4501 aaattaaggt ccggatcgat tcacgtgatg atctgggtcg ccctacgact actccggtag
     4561 agaataaaga gcattttatg gcatttttaa aagatacgca ttcatgaata tcgaaagaaa
     4621 gatccttttg aatccgggtc ccgccaccac gacggatacg gtgaagctgg cgcaggttgt
     4681 tcccgatatc tgtccgcgtg agaaagagtt tgcgggtatg atgaaacagt tacgtgacga
     4741 cctggtccgc gttgcgcatg gagacctctc caaacatacg gccgtcctgt tttgcggctc
     4801 gggtacgatc aatatcgata tctgcctgaa ctctcttctt cctgcggata agaaagttct
     4861 ggttgtcaat aacggtgcct acagcacccg tgcggtggaa gtctgcgaat attacggtct
     4921 tccccatatc gatttgaagt tttccgttta cgaacttccc gacctgtcgg taatcgaaaa
     4981 gacgctttcc gacaatccgg acatcgcttt ggtctatacc acgcaccatg aaacgggtac
     5041 gggtatcttg aaccccatcc gtgagatcgg aaaaatagcc cattcgcacg gtgccgtttt
     5101 tgttgtcgac accacttcct ccctgggtat gattcctttt gatatcggga aggataatgt
     5161 tgacttttgt atggcttcgg ctcagaaagg ccttcaggcc atgacggggc tttcctttat
     5221 cataggtgat gaatccctga tacgtgcttc aagggattat ccgaaacgtt cctactattg
     5281 taacctctat ttacaatacg attactttga gaagacgggc gagatgcatt ttactcctcc
     5341 tgttcaaacc gtttacgctg cccgtcaggc tcttgatgaa tattttgcag taggtgaaga
     5401 ggctaaattc gcccgtcaca agagggtctt tgaagccatc cataaaggtt tgcaagagct
     5461 tggtcttcag tatgcgatca aacgtgaatg gcagtcgggt cttgttgttt ctgtattgta
     5521 tcctgatgat cccctctggg attttgataa ggttcatgat tactgctatg aacgtggctt
     5581 tacgatctac ccgggtaaga tttccacaac gaatacattc cggctttgtg cgttgggaga
     5641 gattgatgtg gaggatattg agaggttctt tgaggtgatg agggaagcaa tttcatttct
     5701 caaaatcagt tttaaaaata tagtttaatt atggaagaga atcaaataac tgtaacttcg
     5761 cctttattgc cttctttaga cgatttttta ccatatttag aggatatatg gaagcgtaaa
     5821 tggattacca ataatgggta ttatcatcaa gaattggaga aagctttgtg ccaatacttg
     5881 aaagtaccat acatctcttt gtttacaaat ggtactttgc ctttaatttg ctctttacaa
     5941 gctttgagaa ttactggtga agttataaca acaccataca gctttgtagc aacaacgcat
     6001 gctttatggt ggaatggcat taagcctgtg tttgtggata ttgatcctaa aacttgcaat
     6061 attgatccga ataagattga agcagctatt actcctaaga cgacagctat tatgccagtt
     6121 catgtctatg gaaatccttg cgattttatt gctatccagg atattgcaga taaatatgga
     6181 ctaaaagtta tttatgatgc ggctcatgct tttggagtag aggtagatgg aaaatctctt
     6241 ctagagtttg gagatatgtc cacactaagt tttcatgcaa ctaaggttta taatacaatt
     6301 gaggggggag cattagtttg tcatgaccgg cagattaaag agagagttga ttttttgaag
     6361 aattttggtt ttgctggtga aactcaaatt gtggctcctg gaatcaatgg gaaaatagac
     6421 gagattcgtt ctgcatacgg actacttaat ttaaaagctg ttgattctgc tattgaatac
     6481 cgacatcaaa tatctaaaag atatcgtgag ggattaggag gtattgatgg tattagttat
     6541 atgcctgaaa tgcataatat acgtcataat tattcttatt ttcctatctt tatagattct
     6601 gtaaagtatg gtattactcg tgatgaactt tatgaaaaaa tgaaacgaaa tggtgtgtgt
     6661 ggtcggagat atttttatcc attaataaca aacttttcaa cgtactgtgg gcttgattcc
     6721 gctcaaataa gtaatcttcc tgttgcaaat agaatagcta actctgtcat ttgtctgcca
     6781 ttacatactg gcttaacttc tattgatgtt gaacgtataa ttgaactttt aaaaaaatga
     6841 catcttttta ttcagaaaaa gaattggcaa atataggttt agcagtatac ggcacaaatg
     6901 ttctgatttc taggaaagtc tctttttatt ctcccaagaa tatatatata ggaaataatg
     6961 tacggataga cgatttttgt atattgtctg gcaaaattct catcggttcc aatatacata
     7021 tatctgctta tgtagctata tatggaggat atggagtggt tttagaggat tatgtgggta
     7081 tatctcctag aacaacgatt tatagtgcaa tggatgattt tagtggtgat tatttagtag
     7141 gtcctattca tgataaaaga ttaactcatg ttattggtgg agaagttcga atttgtaagt
     7201 ttgctcatat tggcgcaaat actattgtat atcccggatg ttctattggt gaaggaactg
     7261 tagttggagc aatgtctatg gttcggaaat cattggatgc ttggggagtt tatattggta
     7321 tacctgctaa atttctaaaa aatagaaata aaaatatgca aagtttgatt t
//
