LOCUS       c00102_gnlPro..         6198 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AFNAMJJP_102.
ACCESSION   c00102_gnlPro..
VERSION     c00102_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 07:55:41
            Original ID  :: gnl|Prokka|AFNAMJJP_102
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6198
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6198
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1014:5157]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1015..5157
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..6198
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..6198
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(3..233)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg102_1"
                     /sec_met_domain="IlvN (E-value: 1.6e-17, bitscore: 52.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQMNFGGVVENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRQGKTYEKAVEDGWVPG"
     CDS             complement(283..1008)
                     /locus_tag="ctg102_2"
                     /transl_table=11
                     /translation="MEKVGLFHFVAEPYLMDFRGRVTLPMIGNYLIHAASSHAGERGFG
                     FNDMSERHTAWVLSRLAIEMKEYPTAFDKINLYTWIDEVGRLFTSRCFELADENGKTFG
                     FARSIWAAIDVETRRPTLLDIEALGKYIDERPCPIEKPGKIMPAENRAEGIPYSIKYSD
                     LDINGHFNSVKYIEHLLDLFDIDQFKTREIGRLEIAYQSEGKQGMPLTLHKAESAPDKQ
                     DMAICHEGKAICRAAVTWR"
     CDS             complement(1015..1569)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_3"
                     /sec_met_domain="ALS_ss_C (E-value: 6.1e-18, bitscore:
                     53.4, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKKLYTVIIFSENIVGLLNQITIIFTRRQLNIETLSVSPSAIK
                     GIHKFTITIFADEDMIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEGLIRKYNARILEMNETCVVLEKSGHYDETQALFNELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLADMERKLHEKQQ"
     CDS             complement(1585..3288)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8.8e-51, bitscore:
                     160.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LRHVLVRHEQGATHAAQGYARVSGKVGVTLVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRKPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGLVDYEYKKVDYVRSYQPEPDIKKDRIKAAADLINEAKKPFCLVGQGVLLGG
                     AEEELKAFLQKNDIPAGSTVLGLSALPTDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFDRDEKEEYDKVIEKELYPTEGQLKMGEVVRKVSEATGNDAVLVTDVGQNQM
                     MGVRYFKYKQTRSVVTSGGLGTMGFGLPAAMGAKFGAPDRTVCFFTGDGGMQMTIQELG
                     TIMQEKLNVKIIILNNNFLGMVRQWQELFFHERYSNTIMENPDFVAIAKAYGIASRAVE
                     KREELDDAIAEMLNHDGAYVLVANVETCGMVYPMVPAGGSVTNMIMGDEK"
     CDS             complement(3322..5157)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_5"
                     /sec_met_domain="ILVD_EDD (E-value: 2.9e-217, bitscore:
                     710.6, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNPLRSSFSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSFT
                     QFVPGHTHLHEIGQLVKAEIEKQGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTVFVSGGPMEAGELDGRHLDLID
                     AMIESADTSVSDERIEQVERHACPGCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     KNRIQLFRDAAKQIVENAYKYYRDGDDSVLPRNIATRQAFLNAMSLDIAMGGSTNTVLH
                     LLAVAQEAGADFHMEDIDMLSRKTPCLCKVAPNTHTYHVQDVNRAGGILGIMNELMKAG
                     LVDGSTRRADGLTLAEAVDKYAVTSPNVTEEAIRKYKSAPAHRFSIQMGSQESYYKELD
                     TDRAEGCIRDVEHAYSKDGGLAVLRGNIALDGCVVKTAGVDESIWKFSGPAKVFDSQDA
                     ACEGILGGKVVSGDVIVITYEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHISPEAASGGAIGLVRDGDIIEINIPERSINVRLSDEELAERRKAEEARGKK
                     AFTPPMRQREVSKALRAYGKMVSSADKGGVRIVED"
ORIGIN
        1 tcacccggaa cccatccgtc ctcaaccgct ttctcgtaag tcttaccttg gcgctggcca
       61 acgattacgt tgaagccatt gtcacgaagg ttcaatgact gtcccggtcc ctgtacgcca
      121 tagccgataa cagcgattgt ctcatctttt aatatctctc ttgccttttc caacggaaat
      181 tcctcgcggg tcattacatt ctctacaaca ccgccaaaat tcatttgtgc cattttcttt
      241 ttaactatta atgtttaaaa acctatttat gtatctcttt tattatctcc aagtaaccgc
      301 cgcacgacag atcgcctttc cctcatggca aatagccatg tcttgcttat cgggagcgga
      361 ctccgcctta tgaagcgtaa gcggcatacc ttgtttaccc tcggattggt aggcgatctc
      421 cagacggccg atctcacggg tcttgaactg gtcgatatcg aacaaatcca gcaggtgctc
      481 gatatacttc acgctattga agtgaccgtt gatatccaag tcgctgtatt tgatcgaata
      541 cgggattccc tccgccctat tctccgccgg catgatcttg cccggcttct cgatcgggca
      601 cggacgctcg tcgatatatt tgcccaatgc ctctatatcc aataaggtag gacggcgggt
      661 ctccacgtcg atagccgccc aaatagaacg ggcgaatcca aaggttttcc cattctcatc
      721 cgccagctcg aaacaacgac tggtgaagag gcgtccgacc tcatcgatcc aagtgtatag
      781 attaatctta tcgaaggcgg taggatattc cttcatctcg atagccagac gggacaacac
      841 ccaagccgta tgacgctccg acatatcatt gaaaccgaac ccacgctctc cggcatggct
      901 ggaagcggcg tgaatcaaat agttaccaat catagggagc gttacacgtc ccctgaaatc
      961 catcaaatac ggctccgcca caaaatgaaa taatcctact ttctccatat cttattattg
     1021 ttgcttttca tgtaactttc tctccatatc ggccaacata tcgctcaagc gctccacctt
     1081 gctcttcgtg atagccacac gtccggagcg gatgaattgc aggacaccga tcgtctcgct
     1141 caactcattg aacaaggctt gtgtctcgtc atagtggcca ctcttctcca ataccacgca
     1201 ggtctcgttc atctccaaga tacgagcgtt gtatttacgg atcaatccct ccacggttcc
     1261 catcttgatg aaaagctcgg tacttagctt ataaagggcg atctcttgat aaaccagatc
     1321 ctcatccgta ttataataag ccttcaagat atccacacgt ttatcgatct gtttcaccac
     1381 cttatcgatc atatcctcat cggcgaatat cgtgatcgta aacttatgga tgcccttgat
     1441 agcggacgga gagacggaca gagtctcgat gttcagctgt cggcgtgtaa agataatcgt
     1501 tatctggttc aaaagaccta cgatattctc tgaaaagata ataacggtat ataatttctt
     1561 tgttgtcata gcttcatctc ctccttattt ctcgtctccc ataatcatgt ttgtcacgct
     1621 tcccccggca ggaaccatcg gatacaccat tccgcaagtc tccacgttag cgaccaacac
     1681 gtaagcgccg tcgtggttta gcatctcggc gatagcgtcg tccaattcct cccgcttttc
     1741 aacggcacgg ctggcgatac cataggcttt agcgatcgcc acgaaatccg gattctccat
     1801 gatggtgttt gaataacgct cgtggaagaa caattcttgc cactgacgta ccatacctaa
     1861 gaagttatta ttaagaataa taatcttcac gttcagtttc tcctgcatga tggtacccaa
     1921 ttcctgaatc gtcatctgca tacccccatc accggtaaag aagcagaccg tacggtctgg
     1981 agccccgaac ttagcgccca tagcggccgg cagaccaaat cccatcgtac ctaaaccacc
     2041 ggaagtcacc acgctacggg tttgtttata tttgaaatag cggacaccca tcatctggtt
     2101 ctgcccaacg tcggtcacca atacagcgtc gttaccggtc gcctcggaaa ccttacggac
     2161 tacctcgccc attttcagtt ggccctcggt cggatacaat tccttctcga ttaccttatc
     2221 gtattcctct ttctcgtccc gatcgaactc ggcattccat tccggacgtt tacgttcttc
     2281 caacaacgcc gtgatcatcg gtatcgtgtg cttggcatta cccagcacct ttacatctac
     2341 ggggacgttc ttaccgattt ccgagttgtc gatatccaga tggataatct tggcttgctt
     2401 agcgtatgtc tttaaatcgc cagtcacacg gtcgtcgaaa cgcataccga tagcgatcaa
     2461 tacatcacac tcattcgttt tccggttcgg ccctacgttt ccatgcatac cgagcattcc
     2521 cttgttcaat gggaaatcgg ttggcaacgc agataagccc aataccgtag atccggcagg
     2581 tatatcattc ttttggagaa acgctttcaa ttcctcttcc gcaccgccta acaatactcc
     2641 ctgcccgacc agacagaagg gtttcttcgc ctcattgatt aaatcggcgg cggccttgat
     2701 acgatccttt ttgatatccg gctccggctg ataactacgt acgtaatcta ccttcttata
     2761 ttcatagtcc accagcccta cttgcgcgtc cttcgctaaa tccagcacaa ctggacccgg
     2821 acggcctgta gaagcgatat aaaaagcacg agaaacagcc catgcgatct cctccggctt
     2881 gcggatttga taagcccatt tcgtgatcgg ttgcgtgatg ccaatcacgt cgacttcctg
     2941 aaaagcatcg gttcccaaca acggcgaggg tacttgaccg gcgattacga ccattggcgt
     3001 actatccatc agcgcgtcag cgatacccgt gatggtattc gtagcgcccg ggccggaagt
     3061 aaccaacgtc actcctacct tgccggatac acgagcatag ccttgagccg catgggtagc
     3121 gccttgctcg tggcgcacca atacatgcct caactggtcc ctataatcat ataaactgtc
     3181 gtaaataggt atcgcctgtc cgccgggata accgaagata gtatctactc cttcagcaat
     3241 caacgctttc agcaaagctt ccgaaccggt tatcttttgt ttctccataa gaaataacgt
     3301 gtttaatgta tattattggc tttaatcttc aacaatcctt acacctccct tatcggcgga
     3361 gctaaccatc ttcccgtacg ctctcaacgc tttcgatacc tcacgctgac gcatcggcgg
     3421 cgtaaaggct ttctttccac gcgcctcttc cgctttacgg cgctcggcca actcctcgtc
     3481 gctcagccgc acgttgatgg aacgttccgg gatattgatc tcgatgatat ccccgtctct
     3541 caccagtccg atagcgccac cggaagcggc ctcaggagag atatgcccga tagaaagacc
     3601 ggacgtaccg ccactgaaac gaccatccgt gatcaaggcg cactccttac ctaagtgacg
     3661 gctctttata taagaggtag gatataacat ctcttgcatt cccggccctc ctttcggacc
     3721 ctcatacgtg atgacgatca catcgcctga aacgaccttg cctcctaaaa tgccctcgca
     3781 agcggcatcc tgtgaatcga agactttcgc cgggccggag aatttccaaa tactctcatc
     3841 cacgccggcg gtttttacga cacatccgtc caaggcgata ttccctctca aaacagccaa
     3901 gccgccatcc ttggaataag cgtgctccac gtcacggata caaccttcgg cacgatccgt
     3961 atctaattcc ttataataag attcttggga acccatctgg atactgaacc gatgagcggg
     4021 agcgctcttg tatttacgga tcgcctcctc cgttacgttc ggggaagtga cggcgtattt
     4081 atcaacagcc tcggccaagg tcaggccgtc cgcacgtctc gtgctgccat ccacaagccc
     4141 ggctttcatc aactcgttca tgataccgag gattccaccg gcacggttta cgtcttgtac
     4201 atgataagtg tgcgtattcg gggctacctt acacaggcaa ggtgtcttgc gggataacat
     4261 atcgatatcc tccatatgaa aatcggcacc ggcttcttgt gccacggcca ataagtgaag
     4321 caccgtattg gtagaccccc ccatggcgat atccagcgac atggcgttca agaaagcctg
     4381 acgggtagcg atgttgcgag gtaacacgga atcatccccg tcacgatagt atttgtaagc
     4441 gttctcaacg atttgcttag ccgcgtcacg gaaaagttgg atacggttct tatgggtagc
     4501 cacgatcgtc ccgttccccg gaagcgccag accgatcgcc tcgttcaagc agttcataga
     4561 gttagcggta aacataccgg aacaacaacc gcaacccgga cacgcatggc gttccacctg
     4621 ctcgatacgc tcatcgctta ccgatgtatc ggcggactca atcatcgcgt cgatcaaatc
     4681 cagatggcgg ccatccagct cacctgcctc catcgggcca ccggacacga acaccgtcgg
     4741 gatatttaat cgcatggaag ccataagcat acccggcgtg atcttatcgc aattgctgat
     4801 gcaaaccata gcgtccgcct tatgggcatt taccatatat tccacgctgt ccgcgataat
     4861 gtcgcgtgaa ggaagcgagt aaagcatccc atcgtgcccc atagcgatac cgtcatcgat
     4921 agcgatcgta ttaaattcag cggcgaaaca accttgtttc tcgatctcgg ccttgaccag
     4981 ttgcccgatc tcatgcaaat gcgtatgccc cggcacgaac tgggtaaatg aatttacgat
     5041 agcgataata ggcttgccga actgttcctc tttcatcccg ttggcacgcc atagcgcacg
     5101 ggctccggcc atcctacgac cttcggtgct aaatgagctt cttaacggat tcttcatctc
     5161 tttcctattt tttgttcgta gagcgcttta tccacgcctc taccttgaat tatttataat
     5221 aaaaaaagcc tttccctata tggagaaagg cttaagaaat atctctacga cttcacaact
     5281 tcttacacac ctttctcctt acctactaat gactagaagg accaccacga gaataatatg
     5341 caatacgttg ttcatcatct tttcttattg tctttgtttg tttgacgctg caaatgtaga
     5401 acaataattg atatgcgcaa aggatttaaa agaaaattct ttatttttct ttcaattctc
     5461 aagcaaatat cattttagga ttgcatttta acaggagcaa gagtgtatta cttaggaatc
     5521 ggaaggtata gaagagaaaa aacttcgatt tcctactaag gacagcgaaa agaaaaatgt
     5581 catctagaat aaatttcaga taacattttt atcagataat acgacttacg ataacacgta
     5641 tctcataaga aaatcccatt ctagcgacaa aaaagataca tataaactcc aaatcacata
     5701 tttattaaca cttgtagact ataaatagcc ttgaaaaaat tcataataat gttttagaaa
     5761 aaacataagg aagttctccg aagaacataa ggaagaaatt tcatctagta tcggactaaa
     5821 ttttgttaac attcgaatga aaatcacctg aaatcaagac taaatccggc ataacccacg
     5881 ctggaagcag ctcaagcaaa gacattttca aaatgacttt cagacagaga aagccttaaa
     5941 tactcaaccg atagacagct cttcaaacat caatcataaa aaaagaccaa cagcacctgc
     6001 attcaaacat tattctgatt tacacaacca tcaaatgctt gcgtttttcc cgtgcgacca
     6061 agcccccggc cccataattc atcacccaca gagagcaata atagcacttt gacatttcgt
     6121 cagttcacgg tttgataagc cgtttaagta aacggttcat taaatatatc gccgatttcc
     6181 taatacacag catttcat
//
