LOCUS       gnlProkkaDJAIALGN_116  12502 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DJAIALGN_116.
ACCESSION   gnlProkkaDJAIALGN_116
VERSION     gnlProkkaDJAIALGN_116
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 06:59:33
            Original ID  :: gnl|Prokka|DJAIALGN_116
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12502
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12502
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2157:2502]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2158..2502
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12502
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12502
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             40..435
                     /locus_tag="ctg116_1"
                     /transl_table=11
                     /translation="MYLLFIILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSVATAYVVPSSSAAKDVLLEQAQKEQQTNPYNMPTGTAAP
                     QTDATAPAESAPATEAPATETPAPAAE"
     CDS             726..2114
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 91.3; E-value: 8.1e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg116_2"
                     /transl_table=11
                     /translation="MTEQLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AITTTFPEGAMLFGFKMQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGVFHTNIPAPILFCLVMLCVGTIAFFIYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSVMLIFVHTMFAL
                     PILNIWWFATVIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNSYCKGPVVDGAQTYDYTLPMAIFAMFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             2158..2502
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg116_3"
                     /sec_met_domain="PF05402 (E-value: 5.3e-18, bitscore: 55.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 2.2e-10, bitscore:
                     30.2, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKEKINLLEVIPCRNEHIKAEQEGETIVLSFPRFKRSWMSRYL
                     LPKGMSKDIHVRLEEHGTAVWNLIDGQRTVREIIEKLADHFQHEAGYESRVSTYLSQLQ
                     KDGFIKWIID"
     CDS             2523..2648
                     /locus_tag="ctg116_4"
                     /transl_table=11
                     /translation="MDNEVEQLEYYPIRSLSIINFPLSIKKRLPTGGQHILSVRP"
     CDS             complement(2596..2877)
                     /locus_tag="ctg116_5"
                     /transl_table=11
                     /translation="MGGEGHMLDMIRRLKDGKEASRLRRERRNDKLGRLRRNNDPYLLP
                     DTTPEEMERIIKDSEKKKEKDNSYFVWGTLIIMGVLIGCAVLLWAIFF"
     CDS             complement(2899..3963)
                     /locus_tag="ctg116_6"
                     /transl_table=11
                     /translation="MKKLIIATGLLMATSAYAQTEVLTGVTRGKDYGVVYALPKTQIEI
                     EIKANKVNYKPGEFSKYADRYLRLTNVSAEPEEYWELNSVKVKPVGVPNSEATYFVKLK
                     DKTVAPLMELTEEGLIKSINVPYSSNNAKNAANNAVAPQRKANPRDFLTEEILMASSTA
                     KMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNLQEEAMTEMFSGVRNK
                     EEKTFTVRLTPDKEFDNEVAFRFSKKLGIVANNDLAGTPFYISLKDLKTVKIPQEDGKK
                     KKEMEGIAYNVPGQAMVTLTDGKKKLYEGEIPVTQFGIIEYLAPVLFNKNSTIKVYFDP
                     VTGGLLKVDREESK"
     CDS             complement(4037..5548)
                     /locus_tag="ctg116_7"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIEHEPIASIDLMERAAQALTKAITNRWNP
                     ETPVTIFAGPGNNGGDALAIARMMAEKGYKIEVYLFNTKGELSPDCQTNKELVEMMEEV
                     TFHEISTQFVPPTLTPEHLVIDGLFGSGLNKPLSGGFAAVVKYINASPAMVVSIDIPSG
                     LMGEENTFNVKSNIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEEGIEETET
                     NYEMLEIEEIRSLIKPRQQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPLCNNDILQTSAPEAMVEADVSETCFAVPTDTDDYQAVGIGPGLGRNEETEAALIEQ
                     LEHCQTPTVLDADALNILANHRHTLTHLPKGSILTPHPKELERLVGKCQDSYERLMKAC
                     ELAHTAKVHIILKGAYSAIITPEGKCYFNQTGNPGMATGGSGDVLTGVILALLAQGYPA
                     EDAAKIGTYIHGLAGDIAQKKQGMIGLIASDIVTCLPTAWRLVSE"
     CDS             6210..6434
                     /locus_tag="ctg116_8"
                     /transl_table=11
                     /translation="MMEKKRIGSNAGKVWRILNEKGEQSMFTLCHELGLTFEDVAIAIG
                     WLARENKILLRKKEGMLYASIENVEFTFG"
     CDS             6627..8171
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 56.1; E-value: 3.9e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg116_9"
                     /transl_table=11
                     /translation="MSSLKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASSLNNTD
                     LAHWLMYGGLGFMILGNGCFKPTVSSLVGQLYEPGDKRLDAAYTIFYMGVNVGSFAAPL
                     ICGFLGDTGNPQDFKWGFLASGIMTLFTVVLFETQKNKYLFSPSGEPIGIVPDARREKK
                     EDKAEHISHPKMDKRTKVRNIIIITALTVALIAFFSYAFSDDWISVGIFTACIVFPVLI
                     LLDGSLTKVERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTDRSIFGWEMPASW
                     FQSFNPLFVVILAYIMPGIWGFLNKRNMEPASPTKQAIGLLLLSLGYLFICFGVKDAIP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEDGKVKSILGYQIATMYDFFMLFVIMSGVASLILFLLSKKLQKMMHGVE"
     CDS             8213..8749
                     /locus_tag="ctg116_10"
                     /transl_table=11
                     /translation="MDTIQIKDKQFTVSIKEQDIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGVTSTGVIKEVIGLNEDIAGRTVVIVEDI
                     VDTGLTMQRLLDTLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             8783..9352
                     /locus_tag="ctg116_11"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMLDLEVPEDELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTSPLIDWYKNE
                     KKYQHINGLGTMDGIFADICEAVDKL"
     CDS             9365..10531
                     /locus_tag="ctg116_12"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKNRSFGKDGADKVIEVPCGTVVYNAET
                     GEYLCDVTDDGQEVILLKGGRGGQGNSHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSAISAAKPKIADYPFTTLEPNLGIVSYRDGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     ITKSDMLDQELMDEIEPTLPEGVPHIFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEELDYEYEEDADDDDDDLDYEYEEEDWEEK"
     CDS             10555..11340
                     /locus_tag="ctg116_13"
                     /transl_table=11
                     /translation="MLGYESLSSYSNISHFVTTRQGGCSEGNYASFNCTPYSGDEAEKV
                     RRNQTLLMEGMSQTPEELVIPVQTHEANCLLIGDAYLSASSQQRQEMLHGVDALITREL
                     GYCLCISTADCVPVLIYDKKHSAIAAIHAGWRGTVAYIVRDTLLRMEKEFGTSGEDVIA
                     CIGPSISLASFEVGEEVYEAFQKNGFDMPRISIRKEETGKHHIDLWEANRMQILAFGVP
                     SGQVELARICTYIHHDEFFSARRLGIKSGRILSGIMIHK"
     CDS             11380..12045
                     /locus_tag="ctg116_14"
                     /transl_table=11
                     /translation="MFEIKVSQEIKNACPVFAGAAVYAAVKNTAYCDGLWKEINTFTED
                     LTTTTQMADIKLQPVIAATREAYKRCGKDPGRYRPSAEALRRRLMRGIPLYQIDTLVDL
                     INLVSLRTGHSIGGFDADKIQGKHLELGIGKAEEPFEGIGRGILNIEGLPVYRDSFGGI
                     GTPTSDHERTKMDVGTTHILAIVNGYNGKEGLKEAAEMIQSLLRDYAGSDGGELIYFE"
ORIGIN
        1 gagaaattga ttattaacgc taattcaaaa taactaaaaa tgtacttatt attcattatc
       61 ttaatggtga ttgcagcctt gctgatgtgc ttcatcgtgc tgattcagaa ttcaaaagga
      121 ggcggacttg cttctggttt ttcttcatca aacgctatca tgggcgtgcg caagactaca
      181 gattttctgg aaaaagcaac ttggggtctg gctatcttca tggttgtgat gagcgttgct
      241 actgcttacg ttgttccttc ttcttctgca gctaaagatg tattgttgga acaagcacag
      301 aaagaacaac aaaccaatcc gtataatatg cctaccggta ctgctgctcc tcagacagac
      361 gctactgctc ctgcagagtc tgcaccagca acagaagctc cggctactga aactcctgct
      421 cctgcagcag aataattcag tgacaggata ttcggtttaa acttattgag tgaacgggct
      481 ttttgacccg ttctcttcat tataggcgcg aattacgcga attacaagag attctaatag
      541 aattgtgtaa tacgtgtggt tcgcgcctat ctttattatt gggtccggtc tgctcttctt
      601 catacaggaa tatccggtca gatgtccttt ttcttataaa atgttctcct tttttagtaa
      661 aacaaatgat aattagttaa ctttgttgcc cgttacgaga ttattaactc cttttaaata
      721 ttacaatgac agaacaattg aaacaaaagc tgaatgactc cgcagtgctg cgttggagtg
      781 ttctagcatt agtcgctttt accatgttgt gcggctactt cctcacagac gttatgtctc
      841 ctctgaaacc catgcttgaa aaagaacttc tctgggacag tttagattac ggttttttca
      901 ccagtgctta tggctggttt aatgtattcc tgctgatgct catctttggt ggtatcattc
      961 tggataagat gggagtacgc ttcaccggaa tgggtgcctg tttattgatg gtgtttggtt
     1021 gtggattgaa atattatgct attactacta ctttcccgga aggtgcgatg cttttcggat
     1081 tcaagatgca agtcacattg gctgcattgg gctatgctat tttcggtgta ggagtcgaaa
     1141 ttgcgggtat caccgtttcg aagattatcg tgaagtggtt taaaggcaaa gagatggctc
     1201 tcgctatggg actggaaatg gcgaccgcgc gtattggaac aactttggcc atggtgctta
     1261 ccgttccttt ggcagacttc ttcgggtcta cggatgagag cggcgtattc cataccaata
     1321 ttcccgctcc gattctgttc tgtctcgtca tgctgtgcgt aggtaccatc gcattcttca
     1381 tctatacttt ctatgataag aaactggatg cttcactgga tgcggaagga ctggaaccgg
     1441 aagaaccttt ccgcatgaaa gacatcgtat atatcattac caacaaagga ttctggctga
     1501 tcgcattact gtgcgtattg ttctattcgg ctgtattccc cttcatcaag tatgcggctg
     1561 atttgatggt acagaagtac aatgtagatc cgaaacttgc gggaacgatt cccggattgc
     1621 tgccgattgg cgcgatcatc ctgacaccgt tgttcgggtc attgtatgac cgtatcggta
     1681 agggagccac gctgatggtg atcgggtcgg tgatgctgat tttcgtacac actatgttcg
     1741 ctcttcctat tctgaatatc tggtggtttg caacggtgat catgattatt ctgggatttg
     1801 ctttctcatt ggttccttcg gcaatgtggc cttcggttcc gaagattatt ccggagaaac
     1861 agttgggaac ggcttatgcg ttgatctttt gggtacagaa ctggggattg atgggcgtgc
     1921 ctttgctgat tggatgggtg ttgaattctt attgcaaagg tccggttgta gatggtgcac
     1981 agacttatga ttataccttg ccgatggcta tttttgctat gttcggtgta cttgccctga
     2041 ttgttgcctt gatgctgaaa gcagaaaaca agaagaaagg ctacggactg gaagaagcaa
     2101 atattcagaa ataatccagt atatattcta tctgaaaaga tataaaagag aaaagatatg
     2161 gctacgaaag agaaaataaa cctcctggag gtgatccctt gtcgtaacga acatattaaa
     2221 gctgaacagg aaggggagac tattgtgctc tccttccctc gttttaaacg ttcgtggatg
     2281 agtcgttatt tattgccgaa aggaatgtcc aaagatattc atgtgcgtct ggaagaacac
     2341 ggtacggccg tatggaacct gatagacggc cagcggacgg ttcgtgagat tatagaaaaa
     2401 ctcgcagacc actttcagca tgaagcaggc tacgagtctc gtgtatctac ctatctttcc
     2461 caattacaga aagacggatt tattaaatgg ataattgatt aatggataat tgataatgga
     2521 aaatggataa tgaggttgag cagctggaat attatcccat acgttcatta tccattatca
     2581 attttccatt atccattaaa aaaagattgc ccacaggagg acagcacatc ctatcagtac
     2641 gcccataatg atgagcgttc cccatacgaa atagctgtta tctttttctt ttttcttttc
     2701 cgaatccttg atgatgcgtt ccatctcttc cggagtcgta tccggcagaa gataagggtc
     2761 gttgtttctt ctaagtcgcc ctaacttgtc atttctccgt tcacggcgta agcgggaggc
     2821 ttctttgccg tctttcagcc gacgtatcat gtcgagcata tgtccttcgc cacccatcgt
     2881 tttgtttttt tagaggtttt atttgctttc ttctctatct actttcagta gtccaccggt
     2941 caccggatca aagtaaactt tgatggtcga gttcttgttg aataataccg gagcaaggta
     3001 ttctatgata ccgaactgag taacaggtat ttctccttca tacaatttct ttttgccgtc
     3061 cgtcagcgtc accattgcct gtcccggtac gttataagca atgccttcca tctctttctt
     3121 cttttttccg tcctcttgcg gaatcttcac cgttttcagg tctttcagac tgatgtagaa
     3181 tggagtgcct gccaaatcgt tgttggcaac tatacccagc ttctttgaaa agcggaaagc
     3241 tacctcattg tcgaattcct tatccggagt gaggcggaca gtaaatgtct tttcttcttt
     3301 attgcggact cccgaaaaca tctcggtcat ggcttcttcc tgaagattca ggttgtcgag
     3361 catgattttg agctgtgcgc cgtccgaagg catattatct gcttgtccgc gcaataatgc
     3421 gtttttactt tcgcggatat tatagatttc ctttgctacc agttcggcca tcttggcggt
     3481 tgaacttgcc atcagaattt cttctgtgag aaagtcgcgg ggattggctt ttcgttgggg
     3541 agcaacggca ttgtttgctg cattctttgc attgttgctg ctgtagggga cgttgattga
     3601 tttgataaga ccctcttcag tcagttccat aagaggagct acggttttgt ctttcagttt
     3661 gacgaaataa gtagcttcgc tgtttggtac acctacaggt ttcactttga cactgttcag
     3721 ttcccagtat tcttcgggtt cggcagagac gttggtcagt ctcaggtagc ggtcggcgta
     3781 tttgctgaat tcacccggct tatagttgac tttgtttgct tttatttcta tttctatctg
     3841 ggttttgggg agggcgtaca ctactccgta gtcttttcct cgcgtcactc ctgtcagcac
     3901 ttcggtctgc gcataggcgg aagttgccat tagtagtcct gttgctatga ttaacttttt
     3961 catattcggt tctttttagc tgattttgaa aaacaaagtt aatgaagtta ttgaataaac
     4021 cgtaagttct taacttttat tcgcttacaa gtcgccatgc cgtcggcaga caggtcacga
     4081 tatcacttgc gattaatccg atcatgccct gttttttctg ggcgatgtct ccggccaatc
     4141 cgtgaatgta agtaccgatc tttgcggcgt cttcggcggg atagccttgc gcaaggagtg
     4201 caaggattac tcctgtcagt acatctccgc tgcctcctgt tgccataccg ggattaccgg
     4261 tctggttgaa gtaacatttg ccttcggggg tgataatggc ggaataagct cccttcagaa
     4321 tgatatgtac tttggcagtg tgcgccagtt cgcaggcttt catcagtcgt tcgtatgagt
     4381 cctgacattt gccgaccagg cgttccagct ctttcgggtg aggggtgagg atggaacctt
     4441 tcggcagatg ggtgagcgta tgccggtgat tggccagaat attgagtgcg tcggcatcca
     4501 gtaccgtcgg agtctgacaa tgttccagtt gttctatcag ggcggcttcc gtttcctcgt
     4561 tgcgaccgag tcccggaccg atgccgacag cttggtaatc gtccgtatcg gtaggtacgg
     4621 caaagcatgt ttcgctgaca tctgcttcta ccatggcttc gggggcggac gtttgcagaa
     4681 tatcgttgtt gcataacggc gcgtgtacgg tcagcagacc tactcccgag cgcagacagg
     4741 cacgcgcggc cagtaccgat gcacctgcca ttccttttga gccggctatc agcagggcat
     4801 gtccgaagtt tcctttatgg gcgaattgtt ggcgtggttt gatcagtgaa cggatttctt
     4861 cgatttccag catttcgtag tttgtttcag tctcttcgat tccttcttcg ctcagctgga
     4921 tgtccaataa ctcccattcg ccaacaaatt ctgtattttc ggcaaagagg aaggccagtt
     4981 taggaagttg caggctgaaa gtgacgtccg cacggataat attgcttttt acattgaatg
     5041 tattttcttc tcccatcagt ccggaaggga tgtcgatgga gactaccatg gcgggagagg
     5101 cattgatata tttcacaacg gcagcgaatc ctccgctcaa tggtttgttg agtccggaac
     5161 cgaataatcc gtcgatcacg agatgttccg gtgtcagtgt gggaggtacg aactgggtgc
     5221 tgatttcatg gaaagttact tcttccatca tctctaccag ttctttgttg gtctggcagt
     5281 cgggcgaaag ttcgcctttc gtgttgaaga gatatacttc gatcttgtat cctttttccg
     5341 ccatcatgcg ggcgatggcg agggcgtctc cgccattatt gcccggtccg gcaaagatgg
     5401 tgacaggtgt ttccggattc catctgttgg tgatggcttt agtcagcgcc tgtgcggcac
     5461 gctccattaa atctatggat gcaatcggtt catgttcaat ggtataggca tctaacttct
     5521 taatgctgct gcttggaaat attttcattg cgatattctt ttagttttcg acgcacaaac
     5581 ttacacaaaa actctgaatt aatcctttat tccggttggt tttcggcttt agataaagtg
     5641 gcaaattgaa aaatgcaggg gaaatcagaa gttatcttgg ggtggctttg tcctgtctgt
     5701 ctgtgattcc tcagttgggg ggcggatatt tctctgcaaa ggtacgggca ttcttcagat
     5761 aagatgcgga gacttttcgg ctaagatgca ggcattcttc tcttaaagtg cctttttctt
     5821 tagttgctca cggccgtgac aagacttcgc cacgaccgtg agcaatgcta atcacggtcg
     5881 tgaacaatgc ttgtcacgac cgtggtcagt taatgatatc ggtgctttga tgtaactatt
     5941 ctactgcttt ctccttaatc ttccgatact ttgagagata gttacgcctt ctccggcctg
     6001 ctatagaact gcttccttta tgagtgtctt cggcgtttgg aataaagctg tcagtagata
     6061 tggtacaata taaacagcta atgccttgat tatttgcttt tttcgaaaaa aatgatatct
     6121 ttgtagtgca gtaatgtgct ttacgttatt ctcctgtgct cacaatgttt agattataaa
     6181 tataaattgt ttaatcttct aaagtttgca tgatggaaaa gaaaagaatt ggctcaaatg
     6241 ccgggaaagt atggcgcatc ttaaatgaaa agggcgaaca gtctatgttc accttgtgcc
     6301 atgagttagg tttgacgttc gaggatgtag cgattgctat cggctggttg gcaagggaaa
     6361 ataaaatcct gcttagaaaa aaagaaggaa tgctctatgc cagtattgag aatgttgaat
     6421 ttacttttgg ataaatggcg actgacccac atttaagggg aatatccact tgattattta
     6481 cactgttgaa aacataataa ggtgggtaac tgagacttct tgcacgccat cctgtatttt
     6541 tctattccat aagaatcttc ttttttgagg catttaatct actttttagt acctttgcac
     6601 cccataaact actaaacaca taattcatga gttcattgaa agggcacccg aaaggccttt
     6661 acctaatttt cgcaacgagc acggcagaac gtttcagtta ctacggtatg cgtgccatct
     6721 ttatcctctt tctgacgcag gcattgcttt ttgataaaga agcggcagcc tctatctacg
     6781 gtagctacac cggactggtc tatctgactc cgttgatcgg cggatacatt gccgataaat
     6841 attggggcat ccgtcgttcg gtattttggg gagcggtgat gatggcagtc ggtcagttcc
     6901 tgatgtttat gagtgcctct tcactgaaca atacagacct tgcccactgg ctgatgtatg
     6961 gcggactcgg attcatgatt ttaggtaacg gttgctttaa gcctaccgtt tcttcgctcg
     7021 tcgggcaatt atatgaaccc ggggacaaac ggttggatgc tgcatacacc attttctata
     7081 tgggtgttaa tgtaggttct ttcgctgctc ctttgatttg cggtttcttg ggagacacag
     7141 ggaatccgca ggactttaaa tggggattcc tcgcatccgg aatcatgacg ctgttcactg
     7201 ttgtcctctt tgaaactcag aagaataaat accttttctc tccttccggt gaaccaattg
     7261 gtatcgtccc cgacgccaga cgtgaaaaaa aggaggataa agccgaacat atttcacatc
     7321 cgaagatgga caaacgtacc aaagtacgta atatcatcat cattactgcc cttacagttg
     7381 ccttaatagc tttttttagc tatgccttta gcgatgactg gattagtgtg ggtatcttta
     7441 cggcttgtat tgtctttcca gtactcattc tgctggatgg ttcattgacc aaagtagaac
     7501 gtagccgtat tttcgtaatc tatatcgtag ctttcttcgt cattttcttc tgggcagctt
     7561 acgagcaggc aggagcttct ctgacattat tcgcttccga acagactgac cgcagcattt
     7621 tcggctggga gatgccggct tcgtggttcc agtcattcaa tccgcttttt gtagtgatcc
     7681 ttgcctatat tatgcccggt atatggggct ttctgaataa gcgaaacatg gaaccggctt
     7741 cccctaccaa acaggcaatc ggtctgttgc tgctttctct tggttatctc ttcatctgtt
     7801 ttggagtgaa agatgctatt ccaggagtaa aggtgagcat gatctggctg acaggacttt
     7861 attttattca tacaatggga gaaatcgctc tgtcacctat cgggctttct atggttaata
     7921 agttgagtcc gttacgtttc gcctccttga tgatggggat ctggtatctt tctaccgcca
     7981 ccgcaaataa atttgcaggt atgctgagtg gcctctatcc cgaagacgga aaagtgaaat
     8041 caatccttgg ttatcagatc gctaccatgt atgacttctt catgctgttc gtcattatgt
     8101 ccggtgttgc ctcactgatt ctgttccttc tctcgaagaa attacagaag atgatgcacg
     8161 gggtagaata aaaaattgta tttttgcgac aactttttta aaatgaccgg ttatggatac
     8221 catacagata aaagacaagc aatttactgt ttccattaag gaacaggata ttcaaaaaga
     8281 agtgattcgc gtagcgaacg aaatcaatcg tgatttggca ggtaagaatc cgctcttcct
     8341 cagtgtgttg aacggctcgt tcatgtttac cgccgacttg ctgaagcata ttacgattcc
     8401 gtgcgaaatt tcattcgtga agttggcatc ttatcagggg gtgacttcca ccggagtaat
     8461 taaagaagtg atcgggctga atgaagacat tgccggacgt acggtagtga tcgtagaaga
     8521 tattgtagat accggactga cgatgcagcg tctgctggat acactgggca cacgcaaccc
     8581 cgaagcgatt catatcgcct ctttgctggt gaaaccggaa aagctgaagg tcaatctgaa
     8641 catagaatac gtagcgatgg aaataccgaa tgattttatc gttggctacg gattggatta
     8701 tgatggtttc ggacgcaatt atcccgatat ttatactgta gtagattaaa ttcaaataca
     8761 aattaatttt taggttaaaa agatgttgaa cattgtaatt ttcggtgctc cgggttcagg
     8821 aaaaggaacg cagagcgaac gtattgtaga aaagtatgga atcaaccaca tctcgacagg
     8881 agatgtattg cgtgcagaaa tcaagaacgg cacggaactg ggcaaaactg ctaaaggtta
     8941 catcgaccag ggacagttga ttccggatga attgatgatt gatattctgg caagcgtatt
     9001 cgatagcttc aaagacagca aaggtgtaat tttcgacggt ttcccaagaa caattgcaca
     9061 ggcggaagca ttaaagaaga tgttggcgga aagaggacag gatgtttctg taatgttgga
     9121 tctcgaagtt ccggaagatg aactgatggt acgtctgatc aaacgtggca aagactccgg
     9181 tcgtgccgac gacaacgaag aaacaatcaa aaaacgtctg catgtatatc attcacagac
     9241 atctccgctg atcgactggt acaagaacga aaagaaatac cagcatatca acggtctggg
     9301 tactatggat ggtatcttcg ctgatatctg cgaagcagta gacaaattgt aataaataaa
     9361 aaatatggct gaatcgaatt ttgttgatta cgtaaagata tactgtcgct caggtaaggg
     9421 cggaagaggc tctacgcaca tgaggcgcga gaaatattgt cctaacggag gtcccgatgg
     9481 gggcgatggt ggaagaggag gccatattat cttgcgcggt aaccgtaatt actggacatt
     9541 gcttcacttg aagtatgacc gtcatgcgat ggcaggtcat ggcgaatcgg gcagcaagaa
     9601 ccgtagtttc ggaaaagacg gtgcggataa agtgatcgaa gtaccctgcg gaacggtagt
     9661 gtataacgcc gaaaccggag aatacctttg cgatgtgacg gacgacggac aggaagtgat
     9721 cttgctgaaa ggcggtcgtg gcggtcaggg caacagtcat ttcaagacgg ctacccgtca
     9781 ggctccgcgc tttgcgcagc cgggcgaacc gatgcaggaa atgacggtga tcatggagct
     9841 gaaactgttg gcagatgtag gactggtagg tttcccgaat gcgggaaagt ctacgttgct
     9901 ttctgccatt tcggctgcga aaccgaagat tgccgattac ccgtttacga cactcgaacc
     9961 gaatctggga attgtttcct atcgcgatgg aaagtcattc gtgatggcgg acataccggg
    10021 catcatcgag ggagccagtc agggaaaagg attgggactg cggtttctgc gtcatatcga
    10081 gcgtaactcg ttgctgttgt tcatggttcc ggcagatagc gatgatatcc gcaaggagta
    10141 tgaagtattg ctgaatgagc tgcgtacgtt caatcccgaa atgctggaca aacaacgtgt
    10201 gctggctatc acgaagagcg atatgctcga tcaggagctg atggacgaga ttgaaccgac
    10261 attgcccgag ggtgttccgc atatattcat ttcttctgtt tccggtttgg gaatctcagt
    10321 gttgaaagac attctgtggg aggaactgaa caaggaaagt aataagatag aagacattgt
    10381 tcaccgtccg aaagacgtga cccgtctgca acaggaactc aaggacatgg gcgaggatga
    10441 agaactcgac tatgaatatg aggaagacgc tgacgacgac gatgatgatc tcgactacga
    10501 atacgaagaa gaggattggg aagaaaaatg atttcaatca caagagataa aagaatgttg
    10561 gggtatgagt cgttaagctc atactccaac atttctcatt ttgtaactac ccggcaggga
    10621 gggtgcagcg aaggaaatta tgcgtcattc aactgtacgc cctacagtgg agacgaggcg
    10681 gaaaaggtcc ggcggaatca aacgcttctg atggaaggaa tgtcgcagac acccgaagaa
    10741 ctggtgattc ctgtgcagac tcatgaggcg aattgcctgc tgatcgggga tgcttattta
    10801 tcggcttcgt ctcaacaacg acaggagatg ctgcacggag tggatgcttt gattacccgc
    10861 gagttgggat attgcctttg catttctact gcagattgtg ttcctgtgtt gatatatgat
    10921 aagaaacata gtgccatagc tgccattcat gccggatgga gagggacggt agcatacatc
    10981 gtgcgtgata ctttgttgcg gatggagaag gagtttggca caagtggaga agatgtgata
    11041 gcctgtatcg gtccgagtat ctcattggct tcttttgaag tgggtgagga agtgtacgaa
    11101 gcatttcaga agaatggttt tgatatgcct cgtatttcta tcaggaaaga ggaaaccgga
    11161 aaacatcata tcgacttgtg ggaagcgaac cggatgcaaa tccttgcttt cggtgtgccg
    11221 tccggccaag tggagcttgc ccggatatgt acgtatattc atcacgacga gtttttctcg
    11281 gcaaggcgtt tgggcattaa gtccggacgg attctgtcgg ggatcatgat tcataaataa
    11341 tagacttgaa cgtaagttga tataaacttg aatagaagta tgtttgaaat aaaagtatct
    11401 caggaaataa agaacgcctg ccctgttttt gccggagcag ccgtatatgc agcagtgaag
    11461 aatactgctt actgcgatgg actttggaaa gaaataaata ctttcacaga agacttgact
    11521 accaccaccc aaatggcaga cattaagttg caacctgtga ttgctgctac ccgtgaggct
    11581 tataagcgtt gcggaaaaga tccggggcgt tatcgtccgt cggcagaagc gctgcgccgt
    11641 cgcctgatgc gtggcatccc tttgtatcag attgatactt tggttgacct tatcaatctg
    11701 gtttctctcc gtaccggaca ttctatcggt ggcttcgatg cggataagat acagggtaaa
    11761 catcttgaac ttggcattgg caaagcggaa gaacctttcg aaggtatcgg tcggggcatt
    11821 ttgaacattg aaggattgcc ggtgtacaga gattcttttg gaggaatcgg gacaccgaca
    11881 agcgaccacg aacgtacgaa gatggatgtc gggactactc atattctcgc gatagtcaac
    11941 gggtataacg gaaaagaggg attaaaggaa gctgctgaaa tgattcaatc cttactgagg
    12001 gattatgccg gatcggatgg cggcgagctt atctattttg aataataaag gaatacatga
    12061 agaacatact tattttattg acagtcctgc ttttaccaac tcttgcttat gcgcaaagta
    12121 aatcctcttt ttcttctatg gaggtgaatc atgtacgggt tgctactccc ggactttttg
    12181 cgaaaagcaa tcatatatat ctgcatttgg attctttgca agagcatgaa tatgcttttc
    12241 ccttaccggg agccaaagtt atttccgctt acggaactcg cggaggacat tcgggagcag
    12301 atataaagac gtgtgccaaa gatacgattc gtgctgcttt tgatggagtc gtacgtatgt
    12361 cgaagccata ttatgcttac ggaaatttgg ttgtagtccg tcatgcgaac gggctggaaa
    12421 cgatttacag tcataacttc aagaatttgg tacagagcgg agatacggtg aaagccggac
    12481 aacctatcgg actgaccgga cg
//
