LOCUS       c00063_gnlPro..        16345 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DJAIALGN_63.
ACCESSION   c00063_gnlPro..
VERSION     c00063_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 13:13:16
            Original ID  :: gnl|Prokka|DJAIALGN_63
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16345
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..156
                     /locus_tag="ctg63_1"
                     /transl_table=11
                     /translation="LAMTAAIRKTFAEKPAEFDPRKYLGPARDNMEKLYKHKILNVLGS
                     DNKLAE"
     protocluster    1..16345
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1783:6345]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1784..6345
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..16345
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16345
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(236..484)
                     /locus_tag="ctg63_2"
                     /transl_table=11
                     /translation="MAFIYFYSLKDKKNTERCLEAFLKTRPKEDKEEEAKLNERGELVL
                     GTKNYYNAAANWLKDIQSKQKIEDFFLGGNVPAQKPE"
     CDS             761..1168
                     /locus_tag="ctg63_3"
                     /transl_table=11
                     /translation="MCFVIFLFRIIADTQIITGMKRTVALAHQVFITLDSGRIILIQTI
                     CQCILAVDSDVGGVNLPIFLRGFNCFVEIRTGYVQCGELGGGKIVVGVFLLYIIVAPRG
                     GEKLSHTFETLGLQMQGDGGTVFLCHQTTFS"
     CDS             complement(1784..2944)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_4"
                     /sec_met_domain="OAD_beta (E-value: 2.3e-153, bitscore:
                     500.7, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFINFLGNNLADFWTYTGFANATGGHIAMIIIGLGFIYLAVAK
                     EFEPMLLIPIGFGILIGNIPFNMDAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYMIALEMGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRLLTTKHERVIRMKPPRAVSHTEKVIFP
                     IIGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDVITILLGLTVGAS
                     TQASEFLTLDSIKIFALGALSFIIATASGVIFVKIFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             complement(2946..3380)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 66.7; E-value:
                     4e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_5"
                     /sec_met_domain="Biotin_lipoyl (E-value: 1.4e-21, bitscore:
                     66.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNSYKVTIGDIEDNIAHVEVNGTHYKVEMEKQPKAT
                     PKPAVVRPMPNSPAAPTTPVVKPAAPSTGKSGVKSPLPGVILDIKVNVGDTVKRGQTII
                     ILEAMKMENNINADKDGKVTAINVNKGDSVLEGNDLVIIE"
     CDS             complement(3405..4325)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_6"
                     /sec_met_domain="OAD_gamma (E-value: 6.1e-15, bitscore:
                     46.2, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLLLLIGLTSCGEQKSNNKLLLNEVLIDNQNNFQD
                     DYGLHSAWIEIFNKSYGSADLAACLLKVSSQPGDTVTYFIPKGDILTLVKPRQHALFWA
                     DGEPNRGTFHTSFKLNPETANWVGLFDSGRKLLDQVVIPAGTLGPNQSYARISDGAADW
                     EVKGGSKDKYVTPSTNNKTLDSNAKMEKFEEHDSVGIGMSISAMSVVFCGLILLFIAFK
                     VVGKVAVNLSKRNAMKAKGIDKVEAKELSQAPGEVYAAISMALHEMQDEVHDVEETVLT
                     ITRVKRSYSPWSSKIYTLRENPNRK"
     CDS             complement(4357..5910)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_7"
                     /sec_met_domain="CT_Btheta (E-value: 7.2e-291, bitscore:
                     955.2, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIERRAVARIGGGEKAIAKQHEKGKYTARERIAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYLFAQDFTVTAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAKTEEEGLALIRTLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDSPN
                     KPYDMYEVISAIVDNGEFLEIQKDYAKNIIIGFARFNGQSVGIVANQPKFLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKDQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLSNPAKKHGNIPL
                     "
     CDS             complement(5941..6345)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_8"
                     /sec_met_domain="Glyoxalase_4 (E-value: 2.3e-24, bitscore:
                     76.4, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGETKIELLEPTCPESTIAKFIENKGAGVHHVAFAVEDGVANALAEAESKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             complement(6519..7517)
                     /locus_tag="ctg63_9"
                     /transl_table=11
                     /translation="MPLKLTTYYRGKDIPDLPGTNTFHSKELFQIYESTPGYTPLLIVA
                     TEEGRPVARLLAAIRKTKKWLPSSLVKQCVVYGAGEFLDTSLPASKEKEEEIFGEMLEH
                     LTQEASRTCILIEFRNLDNSMFGYRFFRKNDFFPVNWLRVRNSLHSTQKAEDRFSPSRI
                     RQIRKGLKNGAKVVEAHTVEEIKEFSRMLHKVYSSRIRRYFPANDFFRHMNSMLIRGKQ
                     AKIFIVKYKEKIIGGSVCIYSGENAFIWFSGGMRKTYALQSPGILAVWKALEDAHERGF
                     RHMEFMDVGLPFRKHGYRDFVLRFGGKQSSTRRWFRISWPWLNNLLVKFYV"
     CDS             7841..10960
                     /locus_tag="ctg63_10"
                     /transl_table=11
                     /translation="LCAPSAISVYAENGVNDITVQAVMQTKTVKGTVLDENGEPLIGVS
                     IVVKGTSTGTITDFDGKFSINLPGGSKELVVSYIGYKEQAIIVSGNAPLNIKMVPDTQA
                     LDEVVVIGYGTVKKRDLTGAVASVKSEDITMNPGVNPMDALQGKIAGLDITNSSGQAGS
                     SPTVQLRGTRSLQLDEDGNISSDAFKPTYIIDGMPGDIATLNPNDIESIEVLKDASSTA
                     IYGSSGANGVIIVTTKGSKSGKPVINFNAYAGTTMGARVPKMRTGDSYINYIKDSYKPV
                     GTTNEEEIFGERYDAIKNNQWVNWGDEVLHSGLKQNYSISVAGGTEKTKAYFSLNYTDE
                     KSMYENDDYKVYSTRVRIDQEINKWMNAGINVQASFSNKNSRNAVLERALFATPLGVPY
                     NEDGSITEFPIPGSSSDPNPLADEQDGVYKNNTKAGRAYVDAYLEWKPVKGLSVKSQLG
                     GSYSQSRAGKFMGEGSYNVLKGSTVAYGEATNKTGYNYKWENIVTYHNTFNKDHDLTVT
                     GVTSWNYNQSEEYYVYGENPATNDMLWYALQNADNKKLNSKYLMSKGMGFIGRVNYSYK
                     GKYLFSASSRYEADSRLSKDNRWNLFPAVSVGWRISDEAFMAGTKSWLDNLKLRVGYGV
                     AGTTAGIAEYSSMASLENVTTSLGGMTVPSAKFTEYITNRNLTWEKTHDLNIGIDASFL
                     NNRIDLTVDLYRTKTTDVILSQALPTSIMGNYTGSTTYKMNKNAAETENRGIELALNTR
                     NIVKKDFTWSSTVTFTANKEKIKSLIEGQDMMFNAKKGDMVFKVGEGVGSFYRYKVLGI
                     WQYSEKETAALFGCEPGDIKLDLPSVKKDGNGYYYMNPEGERVDITAENPYGVRADYDR
                     QVIGRNTPDWTLGFKNNFRYKDFDLSVFLYARWGQMMNYGSVIGKYSPNPDYNIPTYFT
                     YYDKTIEADQNVLFYAIDKSKDRSAYEGYDSMYYVDGSFFKLKNVTLGYTLPGKLTKRF
                     GISNLRVYATMTNLFTYSPNKYVKNYDPEMNGSINFPLSRDCIFGLNLTF"
     CDS             complement(10996..11286)
                     /locus_tag="ctg63_11"
                     /transl_table=11
                     /translation="LPHFIIIAIIGFHTVITMITLIAGARFRFFPNISTRFRTNQIVTT
                     LIDVVDQGCIARVGECLISFQCIRTIGELTRVVGVHFIKTARAPRKNTGNK"
     CDS             11320..12927
                     /locus_tag="ctg63_12"
                     /transl_table=11
                     /translation="VIDGAENVTGDENEINECVAQARCLRAYYYMNLVEQFGNVDLQLK
                     AADSENISFDAHRSTVPEIYAAIIEDLKFAVENLPVSFSDYYSRVTKKSAMGLLARAYI
                     NGAGYDLKDIDGVSFLEKAYDTATTMINNKAIYEWYMHPAFADVFNENNNRNNEEALFI
                     AAGAERNSDAYTNGNYSQSEMFRHFLPSLGTYTDLGLVDKTSNFVYGRPNSNIFLPSKY
                     LMDCFAADMNDSRFRYSFISAYSSYSIPAWGATYEYGGSACAKEITSTLATKFGIPASN
                     IGKKVYPHFNLESNSTADANYCQLAIWNADGTAKTTQDKTDGNILHPAMPLDPAEAHQY
                     AVYCSLKTLTEEEKAQYPGLVLNVFDLYDENGTARATYDKPSAASALWLSIYPALSKFN
                     MPGNKFVGRDVQRKTVDVMIMRMAEVYLIAAEASVRLNKGDAAKYINVLRTRAGAGTVS
                     ESQVDLNYIFDEYARELCGECGRWYLLKRNAAFETRLAAYNKRAAEHFKKEFYLRPIPT
                     KYLDAINNPAEFGQNAGY"
     CDS             13114..13656
                     /locus_tag="ctg63_13"
                     /transl_table=11
                     /translation="MIEEMLAYNREFVKNEGYKEYITNKYPDKKIAILSCMDTRLTALL
                     PAALGIKNGDVKMIKNAGGVISHPFGSVIRSLLVAIFELGVEEIMVIAHSDCGACHMHS
                     EEMLEKMKARGINADYIHMMSFCGVDFHSWLDGFEDTEKSVRGTVDFIVHHPLIPSDVK
                     VHGFIIDSTTGELTRIV"
     CDS             13878..14591
                     /locus_tag="ctg63_14"
                     /transl_table=11
                     /translation="VLFDFCLTAGFTIRFDVIVLCNSFFHNEYISQCKDTISFLITIGL
                     RYLCIHKSNENGNNMENFSELIKNRRSMRKFTDEELTQDEVVALMKAALMSPSSKRSNS
                     WQFVVVDDKEKLKELSHCKEQASSFIADAALAIVVMADPLASDVWIEDASIASIMIQLQ
                     AEDLGLGSCWVQVRERFTATGMPSDEFVHGILDIPLQLQILSVIAIGHKGMERKPFNEE
                     HLQWEKIHINKFGGK"
     CDS             14594..14929
                     /locus_tag="ctg63_15"
                     /transl_table=11
                     /translation="MGAVKANNNKDTYKATAVAFIVIGTLFLINKLLPFASIGLPWVMN
                     KDNLLLYASISFLIFKRDKSVGFVLLGLWLVMNIGLVMSLLGSLSGYLLPLALLIIGII
                     LFWVSKR"
     CDS             14937..15731
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg63_16"
                     /sec_met_domain="F420_oxidored (E-value: 8e-14, bitscore:
                     42.7, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRSIEDTPVVFLGAGNLATNLAKALYRKGFRIMQVYSRTEESAR
                     TLANEVEAEYITDLKDVSNEARLYIISLKDAAFVELLPQITDGKQHALLVHTAGSIPMN
                     IWEGHAERYGVFYPMQTFSKQREVDFREVPFFIEAKRPEDTELLKAVAGTLSDKVYEAD
                     SEQRRSLHLAAVFTCNFTNHMYALAAELLEKYHLPFDVMLPLIDETARKVHELAPRDAQ
                     TGPAVRYDENVMNKHLSMLADSQALQEIYKLMSKSIHEHHQL"
     CDS             15712..16233
                     /locus_tag="ctg63_17"
                     /transl_table=11
                     /translation="MSTINYDLSRIKALAFDVDGVLSSTTVPLHPSGEPMRTVNIKDGY
                     AIQLAVKKGLHIAIITGGRTEAVRIRFAALGVKDLYMGSAVKIHDYRNFRDKYGLSDDE
                     ILYMGDDVPDIEVMRECGLPCCPKDAVPEVKSVAKYISYADGGRGCGRDVVEQVLKAHG
                     KWMAEDAFGW"
ORIGIN
        1 ctggctatga ctgctgctat ccgtaagact ttcgctgaaa aaccagctga attcgaccca
       61 cgtaagtatc ttggtccggc tcgtgacaac atggaaaaac tgtacaagca caaaatcctt
      121 aatgtgctgg gttcagacaa caaattggct gaataatcac agattatcct attatataga
      181 aaggctgcaa tcgtttgacg gttgcagcct tttttacgta atatccttta tctgcttatt
      241 ccggtttctg agcgggcaca tttcctccca agaagaaatc ttctatcttt tgcttacttt
      301 gaatgtcttt cagccagttg gctgcagcat tataataatt cttagtgcct aaaacgagtt
      361 cgcctcgttc gtttagtttc gcttcttctt ccttatcttc tttcgggcgt gtttttaaga
      421 atgcttccag acagcgttcg gtgtttttct tgtctttcag cgaatagaaa taaatgaaag
      481 ccatatcata gagcagctta tgattttgtt tatcgtattt ccggtagcgt tctctgatcg
      541 attcaatctg ctctttaggc atctgtgcca ttttgtagca gtcggtcatg ccaatataga
      601 gccgtaccat attactgtct ttgggaatag tcagatcaag cgctttttcg agatactcta
      661 cgcctaactt cttccatgaa gtcttggcgc aggcacggcc gagataataa agcaggttta
      721 cgttttcagg atcatgtttt cgggcggctt ccagaaagtc atgtgcttcg taatatttct
      781 cttccgcata atagctgata cccagataat aacaggtatg aaaagaactg tcgccctggc
      841 tcaccaggta ttcataacgc tggatagcgg taggataatc cttattcaga caatatgcca
      901 gtgcattctg gcggttgaca gcgatgttgg tggtgtcaat ctgccgatat ttctccgtgg
      961 cttcaattgc ttcgttgaaa taagaaccgg ctatgttcag tgcggcgagc ttggcggcgg
     1021 caagatagtc gtcggggtat ttctcctgta tattatagta gcaccccgtg gcggggagaa
     1081 gctctcccat accttcgaaa ctttgggcct gcagatgcaa ggcgatggcg gaactgtctt
     1141 tctctgtcat cagactactt tctcctaaag catcctgaaa cttctgtaaa gagagcagta
     1201 gtccgatgta ttgaatacgc acatatttgt tttccggatt cagatcaagt gcctgttcat
     1261 aatatttcag tgcctgttgg tatttggcca atgaacggca gcattcggct gcttcgatat
     1321 atgcacgggt attggcagtg tcattggtta tgatttcctg ataagtggaa agtgcttctg
     1381 tattcatccc aagtccccgt tgtgctttac ctttttgcaa gagtagggga attgtcggct
     1441 tttctttggc aatgagagtg agagctgcct cgtaatcgta gtttgctatt gcttcctgaa
     1501 catgattgat gcgctgcgcc atcaccaggg tggtggtaca aaggaaggcg aggagaataa
     1561 tccgtttcat aaatatttat tttagtgtgt cgtaacaaag acgcaagatg ctaaaaaata
     1621 tcgtatttac gaattattcg tagccttttt ggaatagatt aacggaatga taagagaaga
     1681 taacataatg ataagtgcgg atattgcatc taaaacagca atatccgcac ctaatatttt
     1741 gtcccggcat tccgaatgga agcctgacag gggcaccttg tccctacatt aagaatccta
     1801 acaggatacc ggcagcaaca gctgaaccga ttacacctgc tacgttcgga cccatagcgt
     1861 gcatcagcaa gtagttggtt ggatcatatt ccagaccgac aacttgtgag atacgtgcag
     1921 agtcgggaac ggcagataca cctgcattac cgatcaacgg attgatctta ttgcccttct
     1981 tgaggaagag gttgaagatc ttaacgaaga tcacacctga tgcggtagca atgataaatg
     2041 acagtgcacc gagggcaaag atcttgatgg agtcgagtgt caggaactcg gaagcctgag
     2101 tagaggcacc tactgtcaaa cctaacagga tagtgataac gtcaatcagc ggaccgctgg
     2161 ctgtgttagc cagacgacgg gttacaccac tttctttcaa caggttaccg aagaacagca
     2221 tacccagcag aggcagaccg gaaggaacca ggaagcaggt cagcaacaga ccgataatcg
     2281 ggaaaatcac tttctctgta tgagaaacgg cacgtggcgg tttcatacgg ataacgcgtt
     2341 cgtgtttggt ggtgagcaga cgcatgatag gcggctgtat caccggaact aacgccatat
     2401 aggagtaggc ggataccgca atggctccca ttaagttagg tgccagcttg gacgaaagga
     2461 agatagccgt cggaccatct gctccaccga tgataccgat agcaccggcc tgcatcgggt
     2521 caaatcccat ttccaatgcg atcatgtatg caccgaagat accaaactgg gcagccgcac
     2581 cgatcagcat cagcttcgga ttggagatta gcgccgagaa gtctgtcatg gcaccgatac
     2641 ctaagaagat gagcggtgga taccagccgg acgttactcc ctgatacaat atgttcaata
     2701 cagaaccttc ttcatatata ccgactttta gtccggcgtc catattgaaa ggtatattac
     2761 cgatcagaat accgaatccg ataggaatta acaacatcgg ctcgaactct ttggctacag
     2821 ctaagtaaat aaagcctaaa ccgataatga tcatagcaat atgtccacct gtcgcgttgg
     2881 caaatcccgt gtaggtccag aaatcggcaa ggttatttcc taaaaagtta ataaaatctc
     2941 ccatattatt caataattac gaggtcatta ccttcaagaa cagaatctcc cttgttgaca
     3001 ttgatggcag tcactttacc gtctttgtct gcattgatat tgttttccat cttcatggct
     3061 tccaatataa tgatagtctg tcctcttttc actgtatcac ctacatttac tttgatgtca
     3121 aggataacgc ctggcagtgg ggacttaacg cctgatttgc cggtagaagg agcagccggt
     3181 tttactaccg gtgtggtagg agcagccggt gagttaggca tagggcgtac tactgccggt
     3241 ttgggagtag ctttcggttg tttctccatt tctactttgt aatgcgtacc gttcacttct
     3301 acatgagcga tattatcttc aatatctccg atggttactt tgtatgagtt accgttgatt
     3361 ttatatttat attctttcat cgttttatct ttttagggaa tgatttactt tctgttagga
     3421 ttttcacgca aggtgtaaat cttcgaactc cacggtgaat aactgcgctt cacacgagtg
     3481 atggtcagca ccgtttcttc tacgtcgtgt acctcatcct gcatttcgtg taatgccatt
     3541 gaaatagcag cataaacttc acccggagcc tgtgaaagct ctttcgcttc gactttatcg
     3601 atgcctttag ccttcatcgc attgcgtttg ctcaggttga cagcaacttt acctaccacc
     3661 ttgaaggcaa tgaagagaag aatcaatccg cagaatacta cgctcatggc tgaaatagac
     3721 ataccgatac cgactgagtc atgttcttcg aacttttcca tcttggcatt actgtcaagg
     3781 gttttgttgt tcgtgctcgg ggttacgtat ttgtctttgc ttccgccttt tacttcccag
     3841 tctgctgctc cgtcgcttat gcgtgcataa gactggttgg gacctaaagt tcctgctggt
     3901 atgacaactt gatcaagtag ctttctgcct gaatcaaaaa gaccgaccca attggctgtt
     3961 tcgggattca gtttgaagct ggtatggaag gtaccacgat taggttcgcc gtctgcccaa
     4021 aataacgcat gttggcgtgg ctttactaat gtaagtatgt cacctttcgg gataaaataa
     4081 gttactgtat cgcccggctg gctgcttact ttcaataaac aagctgctaa gtctgcgcta
     4141 ccgtatgatt tgttgaatat ttcaatccat gcactgtgca agccgtagtc atcctgaaag
     4201 ttgttttgat tgtctatcag gacttcattc agcaatagct tattgttcga cttttgctct
     4261 ccgcaggaag tcaatccaat cagcaacagc agagaaagga atattccgat tttggttttg
     4321 ttcataatcg ttcttgtttt aatgtgaaaa gttggattac aacggaatat taccatgttt
     4381 cttcgccggg ttagacagtt tcttagtctg caactgctgc aaagcacgga tcacgcggaa
     4441 acgtgtgtta cggggttcga tgacatcatc gatgtaacca tacttagctg cattataagg
     4501 attggcaaac agttttgtat attctgcttc tttttcggca aggaactgag ccggattttc
     4561 ctggtctttg gcttcacgcg cgtacaatac ttctactgca cctgcaccac ccattacagc
     4621 gatttcagct gttggccaag catagttcat gtcaccacga agttgtttac aactcatcac
     4681 gatgtgagaa ccaccgtaag atttacgcaa tgtgattgtt actttaggta cagtagcttc
     4741 accgtaagca tacagcagtt tggcaccatg aaggataacg ccattgtatt cctggcctgt
     4801 tcccggaagg aatcccggta cgtctaccaa cgacacgata gggatattga aagcatcgca
     4861 gaaacgaacg aaacgtgcgc ctttgcgaga tgcgttgctg tcgagtacac cggcaaggaa
     4921 tttaggctga ttggctacaa tacctacaga ctgaccgttg aaacgggcaa aaccgataat
     4981 gatattcttg gcatagtctt tctggatttc caggaattca ccgttgtcca cgatagcgct
     5041 gataacctcg tacatatcat acggtttgtt ggggctgtcg gggataatat cgttcagaga
     5101 atcttccaga cggtcgatcg gatctgtgca atccacgtat ggagcttctt cgaggttgtt
     5161 ttgaggaata tagctcagaa gtgtgcggat caatgccaga ccttcttctt ctgttttggc
     5221 agtgaaatga gtaacacccg atttggtaga gtgaacgctt gctccgccga ggttttcctg
     5281 gcttacgtct tcaccggtta cagttttcac tactttcgga cctgtaagga acatataaga
     5341 agtaccttcc atcatcagtg tgaagtctgt cagtgccgga gaataaacag caccgccggc
     5401 acaaggaccg aagataccgg aaatctgcgg aatgacaccc gaagcgagga tattgcgctg
     5461 gaagatttct gcgtaacctg ccaaagcgtt aataccttcc tggatacgtg caccgcccga
     5521 gtcattgata ccgatacaag gagcacccat cttcattgcc tgatccataa tcttacagat
     5581 cttcagtgac attgtttccg acagtgaacc tgcagtaacg gtaaagtcct gtgcaaaaag
     5641 atatacgaga cgaccttcga tagtaccgca accggttact acaccatcac ccggatagtg
     5701 ctttttctcc atgccgaagt tcgtgcatct gtgctcaacg aacatgtcca tttcttcgaa
     5761 gctaccttca tccaacagca tggctatacg ctcacgcgct gtgtatttcc ctttttcatg
     5821 ttgcttcgca attgcttttt cgccgcctcc gatgcgtgca acggcacggc gttcaataag
     5881 ctctttaatt ttttcaagtt gattactcat gagttcttgt tgttttttta gagtttatga
     5941 ttagtgttcg cagagttctg tcagcacacc cagtgttgat ttcgggtgaa ggaaagcgat
     6001 gttcagacct tcggcacctt tgcggggagc cttgtcaatc agacggattt ctttgctttc
     6061 tgcttctgcc aaagcattag ctacgccatc ttctacggca aatgctacgt gatgaacacc
     6121 tgcacctttg ttttcaataa atttagcaat ggtgctttcg gggcaagtcg gctccaacaa
     6181 ttcgattttt gtttcaccta cctttaaaaa agcggttctt actttttgat cttctactgt
     6241 ttcgatgttg taacatttca gacccaatac gttttcgtag taaggaaggg cttcttcgat
     6301 gctttttaca gcaatgccca gatgctcaat gtgtgaaatc ttcataacta tattttttta
     6361 tatggtttaa ttatgtgctt atatggcata aaacagcaca aagaaagaca tttcttgtct
     6421 aataaagaaa tatttctgca tttaattatt ggggaataaa gcataaaaaa tgctccggat
     6481 gggtgacaaa gacgggtttt gtaatcttga gattacattt agacataaaa cttgaccaga
     6541 agattattca gccatggcca gctgatacgg aaccaacggc gggtactgct ttgtttgcct
     6601 ccgaaacgga gtacgaaatc acgataacca tgtttgcgga agggaagtcc tacatccatg
     6661 aactccatgt gacggaatcc ccgttcatgg gcatcttcaa gtgctttcca tactgccagt
     6721 atgccgggtg actgcagtgc ataggtcttt cgcattcctc ctgaaaacca gataaaagca
     6781 ttttcgccgg aatagatgca gacggagccg ccgataatct tttccttgta ttttacgatg
     6841 aatatttttg cctgttttcc tctgataagc atgctgttca tgtggcggaa aaagtcattg
     6901 gcagggaaat atctccgtat tcgtgaagaa taaactttgt gcagcatccg cgagaattcc
     6961 ttaatctctt ccaccgtatg ggcttctact actttggctc cgtttttgag tcctttccgg
     7021 atctgacgga tacgtgacgg gctgaaacgg tcttccgctt tctgcgtact atgcagagag
     7081 ttacggacac gcagccagtt gaccggaaaa aagtcgttct ttcggaagaa acggtaaccg
     7141 aacatggaat tatccagatt gcggaattca ataagaatgc aggtgcgtga tgcttcttgt
     7201 gtgagatgct ccagcatttc accgaaaatt tcttcctcct tctctttact tgccggtaga
     7261 gaagtgtcca gaaattcacc tgcaccatat accacacatt gtttgacaag agaggaggga
     7321 agccactttt tggtcttgcg tatggcggca agcaggcgtg ctacaggtct gccttcttct
     7381 gttgccacta tcagtagcgg ggtatatccc ggagtcgatt catagatctg aaacaactcc
     7441 ttggaatgaa aagtattggt tcccggtaaa tcaggaatgt cttttccgcg ataatatgtt
     7501 gttagtttaa gtggcatcca aatacaaatt tacacttttt attcttcatt caacaataaa
     7561 aaagagaatt tgttggctta gcctaaaatt tgtcttttta tcctttgcat atatttgagg
     7621 aaaaaaaggc ttggaaaagc gaatttttgt attattgtcg tcctttgtga gtacagaagt
     7681 aaaatggaaa cgtctatgta aaagattatg ctaattgtat tttactaaac aaaggaaaat
     7741 taatattaac tttaaattaa aacgaatgag agagaatgca tttgttgaag cgtggaagac
     7801 acagcataga cgcgtttcca tgattttagg gctgacttta ttgtgtgccc cttctgccat
     7861 atctgtttat gcagaaaatg gtgtgaatga tattactgtg caagccgtca tgcagacaaa
     7921 gacagtgaaa ggaactgttt tagatgaaaa tggagaaccg ttgatcggtg tttctattgt
     7981 ggtgaaaggt acaagtacag gtacgataac tgattttgac ggtaagttct ccattaatct
     8041 tccgggcgga agtaaagaac tggttgtttc ttatatcgga tataaagaac aggctatcat
     8101 tgtgagcgga aatgccccgc tgaatataaa gatggttccg gatacacagg ctttggatga
     8161 ggtagtggtc atcggttacg gtacggtaaa gaaacgtgat ttgacaggtg cggttgcttc
     8221 tgtgaaatca gaggatatca ccatgaatcc gggcgtgaat ccgatggatg cgctgcaagg
     8281 taaaattgca ggtctggata tcactaattc ttcaggtcag gcaggttcgt caccgacagt
     8341 tcagttgcgt ggtacccgct ctttgcagtt ggatgaggat ggtaatattt cttccgatgc
     8401 atttaagccg acttatatta tcgatggtat gccgggtgat attgctacct tgaatcccaa
     8461 tgatattgaa tctatcgaag tactgaaaga tgcatcttct acggctatct acggttcaag
     8521 tggtgcgaat ggtgttatta tcgtgactac gaaaggatcc aagagtggaa aaccggtcat
     8581 caattttaat gcttatgccg gaacgactat gggtgcccga gttcctaaga tgcgtacggg
     8641 tgactcatac attaattata taaaagattc ttataagcct gtcggtacta ctaatgagga
     8701 ggaaattttc ggtgaaagat acgacgccat caaaaacaac caatgggtaa attggggaga
     8761 tgaagtatta cattcaggct tgaagcagaa ctatagtatt tccgttgccg gaggtactga
     8821 gaagacgaaa gcttatttct cgttgaacta tactgatgag aagagtatgt atgagaatga
     8881 tgactataaa gtgtactcta cccgtgtccg tatagatcag gaaatcaata aatggatgaa
     8941 tgccggtatt aatgttcagg catctttctc caacaagaat tcacgtaatg ccgttttaga
     9001 aagagcattg tttgctaccc cattgggtgt tccttataat gaagatggct ctattacgga
     9061 atttccgatt cccggttcat catcagatcc aaatccgtta gcagacgaac aagatggagt
     9121 atataagaat aatactaaag caggaagggc ttatgttgac gcttatcttg aatggaaacc
     9181 ggtaaaagga ttgtctgtca agtcacagct tggaggcagt tattctcaat ctcgtgccgg
     9241 taaatttatg ggagaaggct cttataatgt gttgaaaggc agtacggtgg catatggcga
     9301 agctaccaat aagacgggat ataattacaa atgggaaaac atagtaactt atcacaatac
     9361 atttaataag gatcatgacc tgacggttac aggggttact tcctggaatt acaatcagag
     9421 tgaagaatat tatgtctatg gtgaaaaccc ggcgaccaat gatatgttgt ggtatgcatt
     9481 gcagaatgct gataataaga aactgaacag caaatatctg atgtcgaaag ggatgggctt
     9541 tatcggtcgt gtcaactact catacaaagg taaatacctg ttctctgctt ccagtcgtta
     9601 tgaagcggat tcccgtttgt cgaaagacaa tagatggaat ttattcccgg cagtttctgt
     9661 aggctggaga atctcggatg aagcatttat ggctggtaca aaaagctggt tggataactt
     9721 gaaactgcgt gtaggctatg gtgttgccgg aactactgcc ggtattgctg aatacagttc
     9781 tatggcatct ttggaaaatg tgacaacttc tttgggagga atgactgttc cgtcagccaa
     9841 gtttacggag tatatcacta accgtaatct gacatgggaa aagactcatg acttgaatat
     9901 tggtattgac gccagcttcc tcaataatcg tattgatctg acggtggatt tgtatcggac
     9961 aaaaacaacg gatgtaattc tttcgcaggc attgccgaca tctattatgg gtaattacac
    10021 aggtagcact acttataaaa tgaacaagaa tgctgctgaa acagaaaatc gcggtattga
    10081 acttgctctt aatacccgta atattgtgaa gaaagatttt acttggagct caacagtgac
    10141 atttaccgcc aacaaagaaa aaattaaatc tttgatcgaa gggcaggata tgatgttcaa
    10201 tgcaaaaaag ggtgatatgg tgttcaaagt cggcgaagga gtcggttctt tctatagata
    10261 taaagtgttg ggtatctggc aatatagcga aaaggaaact gctgctttgt tcggatgcga
    10321 accgggcgat attaagctgg atttacctag tgtgaagaag gacggaaatg gttactatta
    10381 tatgaatcct gaaggagagc gcgttgatat tacggcagaa aatccttatg gtgtacgtgc
    10441 ggattatgat cgtcaggtaa taggtcgtaa tactccggac tggacattgg gctttaagaa
    10501 taatttcaga tacaaagatt ttgatttgtc tgtcttcctt tatgcacgtt gggggcaaat
    10561 gatgaactat ggtagtgtga taggtaaata ttcgcctaac ccggattaca atattcctac
    10621 ttattttact tactatgaca agacgatcga agcagatcag aatgtcttgt tctatgctat
    10681 cgataaatcc aaggatagaa gtgcttatga aggatatgat tcgatgtatt atgtggatgg
    10741 atcattcttt aaacttaaaa acgtaacatt gggttatacg ttacccggta aacttacaaa
    10801 acgttttggt atcagtaatc tgagagttta tgcgacaatg accaacctgt ttacttattc
    10861 gccaaacaaa tatgtgaaga attacgatcc ggaaatgaac ggaagcatca acttcccatt
    10921 gtctcgtgat tgcatatttg gtcttaattt aactttctaa aaaatagcaa tatgaaaaag
    10981 atatatagtt tagttctact tgttgccggt gttttttctt ggggctcttg cagtcttgat
    11041 gaagtgaacc ccaacaactc gggtcagttc tccgatggtt cttatacatt ggaaacttat
    11101 aaggcattca ccaactcgtg ctatacagcc ttgatcaaca acatctatca gagtagtgac
    11161 tatctggttt gtacggaagc gggtactgat atttgggaag aacctaaatc gggctccagc
    11221 tatcagcgtt atcatagtta taacggtatg aaaaccgatg atagctatta ttataaagtg
    11281 tggcaatatt cttatctgtg tatcaacagc tgtaatattg tgattgacgg agctgagaat
    11341 gtgacagggg atgagaatga aatcaatgaa tgtgtggcac aggccagatg tctgcgtgct
    11401 tactattata tgaatctggt ggagcagttt ggaaatgtcg atttgcagtt gaaggctgcc
    11461 gatagcgaga atatttcttt tgatgctcac cgttctaccg ttcccgaaat ttatgctgcc
    11521 attatcgaag acctgaagtt tgccgtagag aatctgcccg taagtttcag tgattactat
    11581 agccgcgtta caaagaaatc ggcgatggga ttattggcac gtgcatatat taatggtgcc
    11641 ggttatgatc tgaaagatat cgatggtgtc agctttctgg aaaaagccta tgatacggcg
    11701 acaaccatga ttaataataa agcgatttat gagtggtata tgcatcctgc ttttgccgat
    11761 gtattcaacg aaaataataa tcgtaacaat gaagaagctc tgttcattgc tgcgggtgcc
    11821 gaaagaaatt cggacgctta caccaatggt aactactcac aaagtgaaat gttccgtcac
    11881 ttcttacctt cgttgggaac atatacggac ctgggtttgg tagacaagac ttcaaacttc
    11941 gtttacggtc gtccgaacag taatatcttc ctgccatcca aatatctgat ggactgtttt
    12001 gctgctgata tgaacgactc tcgttttcgt tattcattta tctcagctta ctcgtcttat
    12061 tcaataccgg catggggggc gacttatgaa tatggaggtt cagcgtgtgc caaagaaatc
    12121 acaagcacac ttgctactaa atttggtatt cccgcatcta atataggtaa gaaagtttat
    12181 cctcatttta acttggaatc caatagtaca gccgatgcta attactgcca gctggctatc
    12241 tggaatgcag atggaacagc gaagactact caggataaaa cagatggtaa tattcttcat
    12301 cctgctatgc ctttagatcc ggcagaagct catcaatatg ccgtttattg ttctttgaag
    12361 acgctgacag aagaggaaaa agctcaatat ccggggttgg ttcttaatgt tttcgatctt
    12421 tacgatgaga atggaacagc cagggctacc tatgacaagc ctagtgctgc cagtgctttg
    12481 tggttatcta tttatccggc tctttctaaa ttcaatatgc cgggtaataa gtttgtcggc
    12541 agagacgttc agagaaaaac tgtggatgtg atgatcatgc gtatggcgga agtttacctg
    12601 attgctgctg aagcatcggt acgcttgaac aagggagatg ctgccaaata tattaatgta
    12661 ctccgtacgc gtgccggtgc cggtacggtc agtgagtcgc aagtggatct gaattatatt
    12721 ttcgatgaat atgcccgtga actttgtggc gaatgtggcc gctggtattt gctgaaacgt
    12781 aatgctgctt ttgagactcg tttggctgct tataataagc gtgctgccga gcactttaag
    12841 aaagaattct atttgcgtcc tattcctacg aaatatctgg atgcgatcaa taatccggca
    12901 gaattcggac aaaacgccgg ttattaatca gttaattaat aatcaagcat aattaatagg
    12961 agccgggcag gagatttctc ttgtccggct ctttgtttcc atacctgtat cctgcgtaaa
    13021 agtttaaaaa ggatttccgg tatattttca ttgtttcctg atacagcttt ttattatttt
    13081 ctttattttt gtgtgtccaa acaaaatagc gctatgatag aagaaatgct tgcttataac
    13141 agagagttcg ttaagaacga gggatataaa gaatatataa cgaataagta tcccgataaa
    13201 aagattgcta tcttatcctg tatggataca cgtctgacag ctttactccc ggccgcatta
    13261 ggcattaaga acggagacgt taaaatgatc aagaatgcag gaggcgtcat ttcccatcct
    13321 ttcggtagtg tgattcgcag tctgcttgtc gctatcttcg agttaggtgt ggaggaaata
    13381 atggtgattg cccattctga ttgtggagcc tgccatatgc acagtgaaga aatgcttgag
    13441 aagatgaagg cacggggtat taatgccgat tatattcata tgatgagttt ttgtggagtc
    13501 gattttcatt cttggctaga tggctttgaa gatacggaga agtcggtaag gggaacggtc
    13561 gattttatag ttcatcatcc tttgattccg tcggacgtga aagtgcacgg gtttatcata
    13621 gactccacta ctggagaact gacgcgaatt gtataggaaa tcgccctttc tgcctatcag
    13681 gaactgcata aaacatggtg tcactatcgc aacaggatag tgtcactatc actgtctcat
    13741 ggtgtcacta tgtcattggg ataccgacac tatcccaaat gaaaaaaata aggcagcttt
    13801 ttatcggctg cctttatctt tctgcggtta tatactttct ttgactcatg cactcgtttg
    13861 taacaaacgg ggtgtccgtg ctctttgatt tctgcctcac ggctggcttt acgattcgct
    13921 ttgatgtaat cgtcttgtgt aattcgtttt ttcataatga atatatttct cagtgcaaag
    13981 atacaatttc atttcttatt acgatcggtt tgcgctatct ttgcatacat aaatcaaatg
    14041 aaaacggaaa taatatggaa aatttcagtg aactgataaa gaatcgccgc agtatgcgca
    14101 aatttacgga tgaggagtta acacaggatg aggttgtggc actgatgaaa gctgccttga
    14161 tgtctcccag ttccaaacgt agtaatagct ggcagtttgt ggtagtcgat gataaagaaa
    14221 agttgaaaga actgtctcac tgcaaagagc aggcttcctc gttcattgcg gatgctgctt
    14281 tggcgattgt tgtgatggct gatccgttgg caagcgatgt gtggattgaa gatgcttcta
    14341 ttgcttccat catgatacag ttgcaggcgg aagatttggg gctgggaagc tgttgggtac
    14401 aggttcgcga acgtttcact gcaaccggaa tgccgtctga cgagtttgtt catggaattt
    14461 tggatattcc tttgcaactg cagattcttt ccgtgattgc catcggacat aagggaatgg
    14521 aacgtaagcc tttcaacgaa gaacacctcc agtgggagaa aattcatatt aataagttcg
    14581 gaggaaaata acgatgggag ctgtcaaagc aaataataat aaagatactt ataaggctac
    14641 tgccgtcgct tttattgtta tcggaactct tttcctgata aataaactgc tcccctttgc
    14701 ttctataggt ttgccttggg tgatgaataa ggacaatttg ttgttgtatg cctctatcag
    14761 ttttcttatt ttcaagcgtg acaagtcggt cggctttgtg ctgttgggac tgtggctggt
    14821 aatgaatatc ggtctggtaa tgtcattgct cggttccttg tccggttatc tgttgccatt
    14881 ggcactgttg atcatcggaa ttattttatt ttgggtttca aaacgttaaa gaaacaatga
    14941 aaagaagtat tgaagatacg cccgttgtgt ttctcggtgc cggaaatctg gcaactaatc
    15001 tggcgaaagc gctttaccgg aaaggattcc gtatcatgca ggtgtacagc cgaacggaag
    15061 aatcggctcg tacgttagcc aatgaagtgg aagcggaata tatcactgat ttaaaagacg
    15121 tatcgaatga agcgagatta tatattattt cattgaaaga tgccgctttc gtcgaactgt
    15181 tgcctcagat cactgatggg aagcagcatg cgctgttggt gcatacggca ggcagcatcc
    15241 cgatgaatat ttgggaaggt catgcggaac gctacggagt attttatccg atgcagacgt
    15301 tcagcaaaca acgtgaagtt gattttcggg aagtaccttt ctttattgaa gcaaaaagac
    15361 cggaagatac cgagctgctg aaagcggttg ccggtacact ctctgataag gtgtacgaag
    15421 ccgattcgga gcaacgcagg agtcttcatc tggcagctgt ctttacctgt aactttacca
    15481 accatatgta tgctcttgcc gccgaattgc tggaaaaata tcatttgcca tttgatgtta
    15541 tgcttcccct gattgacgaa acggcacgca aagtgcatga acttgctcct cgtgatgcgc
    15601 agaccggacc ggctgtacgc tatgacgaga atgtgatgaa taagcatctt tctatgctgg
    15661 cagacagtca ggcattgcag gaaatttata aattaatgag taaaagtatc catgagcacc
    15721 atcaattatg atctatcccg catcaaagca ctggcttttg atgttgacgg agtattgagt
    15781 tcgacaacag tcccgttgca tccttccgga gaaccgatgc gtacggtgaa tattaaagac
    15841 ggttatgcca ttcagttggc agtaaagaaa ggactccata ttgctatcat taccggtgga
    15901 cggacagaag cggtacgtat ccggtttgca gcattgggtg tgaaggatct gtatatgggg
    15961 tctgcagtga aaattcatga ttaccgtaat ttccgcgata aatacggtct gtctgatgac
    16021 gaaattctgt atatgggcga tgatgtgcct gatatagaag tgatgcgtga gtgcgggttg
    16081 ccttgttgtc ccaaagatgc tgttccggaa gttaagtcgg tcgcgaagta tatatcttat
    16141 gccgatggcg gtcgtggctg tggacgtgat gtggtggaac aagtattgaa agctcatggc
    16201 aagtggatgg cggaagatgc tttcggctgg tgagttgtaa atcacttaat aataaataaa
    16261 attatgcttg gaaatttaga taaatatcag attatattag cctccaattc tccccgccgg
    16321 aaagaactga tgtcaggttt gggag
//
