LOCUS       c00062_gnlPro..         5734 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OIKCEHMJ_62.
ACCESSION   c00062_gnlPro..
VERSION     c00062_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 13:18:40
            Original ID  :: gnl|Prokka|OIKCEHMJ_62
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5734
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5734
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1275:5734]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1276..5734
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..5734
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..5734
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(2..1132)
                     /locus_tag="ctg62_1"
                     /transl_table=11
                     /translation="LLKYYIMKKFQILVMLLWLSVCLAGAVESKIRLVHGPYLQNLGPD
                     EVTIVWLSDKPSVGWVELAPDDDTNFYATERPKYYDARNGVKNTSTIHTVKIKGLKPGT
                     NYRYRVFVQEVLSHVGHKIIYGNYASTDVYSKKPLVFKTSDPADNSVSFAMVNDIHGKN
                     DLLTNLVSKCDLKKTDFFLFNGDMVSVFNEENHIFDGFMDTATKLFASEIPMYYTRGNH
                     ETRGAFATEFQRYFSPKEENIYYTFRQGPICFVVLDTGEDKPDSDIEYAGITVYDEYRT
                     EQAEWLRRVLDSKEYKDAPFKIIVAHIPPIGGWHGNLEVEQKFMPLLRDAKPDVMLCGH
                     LHRFIHQDATDRTPFPIIVNSNTAILKAAADPKELKI"
     CDS             complement(1276..2319)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg62_2"
                     /sec_met_domain="IlvN (E-value: 3.3e-45, bitscore: 142.3,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.7e-44, bitscore: 140.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVMNFGGVDENVVTREEFPLEKAREVLKDEVIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRPGKTYDKAVADGWVPGETLFGIEEACERATIIQVLLSDAAQIE
                     CWPRIKKYLTPGKALYFSHGFAITYKERTNIIPPADVDVILVAPKGSGTSLRRMFLQGR
                     GLNSSYAIFQDATGRAWDRVIALGIGVGSGYLFETTFKKEVYSDLTGERGTLMGAIQGL
                     LLAQYETLRENGHEPSEAFNETVEELTQSLMPLFAENGMDWMYANCSTTAQRGALDWMG
                     PFHDAVKPVFEKLYREVACGNEAQRSIDTNSKPDYREGLEKELAALRESEMWRAGAVVR
                     KLRPENN"
     CDS             complement(2405..3175)
                     /locus_tag="ctg62_3"
                     /transl_table=11
                     /translation="VVCELPQQKRIMDKDKSKIGEFHFVTEPYLLDFRGRVTIPMIGNY
                     LIHVASSHAAERGFGFNDMSERHTAWVLSRLAIEMIEYPAMSEPITLYTWVDEVGRLFT
                     SRCFELVDGNGKTFGYARSIWAAIDVETRRPTLLDIARLSAYVTDRPCPIEKPGKIAAV
                     ENETEGVPYFIKYSDLDINGHLNSIKYMEHLLDLFDLDLFKTKDIKRFEIAYQSEGKYG
                     MKLMLYKREADNGKYDMAICNEGKAICRAAVMWH"
     CDS             complement(3183..3734)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg62_4"
                     /sec_met_domain="ALS_ss_C (E-value: 3.5e-18, bitscore:
                     54.4, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKKLYTVIIFSENTVGLLNQITIIFTRRQLNIETLSVSPSAIQ
                     GIHKFTITTFADEDMIDKVVKQIDKRVDILKAYYNTDEDLVFQEIALYKLSTELFIKMG
                     TVEDLIRKYNARILEMNETCVVLEKSGHYDETQALFRELSETIGVLQFIRSGRVAITKS
                     RVERLSDMLAEMERKLQEKK"
     CDS             complement(3747..5447)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg62_5"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8e-52, bitscore:
                     163.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKQKITGSEALLKSLIAEGVDTIFGYPGGQAIPIYDSLYDYRDK
                     LKHVLVRHEQGATHAAQGYARVSGKVGVTLVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRKPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGFVEYEYKKVDYIRSYQPEPDINQDRIKAAAALINKAEKPFCLVGQGVLLGG
                     AEEELKAFLLKNDIPAGSTVLGLSALPSDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKVIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFEPDAQEEYEKVIEKELYPMNGSLKMGEVVRKVSEATGNDAVLVTDVGQNQM
                     MGVRYFKYKRTRSVVTSGGLGTMGFGLPAAMGAKFGAPDRTVCFFTGDGGMQMTIQELG
                     TIMQEKLDVKIIILNNNFLGMVRQWQELFFHERYSNTIMENPDFVAIAKAYGIAGRTVE
                     KREELDEAIAEMLNHNGAFVLVANVETCGMVYPMVPAGGSVTNMILGDK"
     CDS             complement(5471..5734)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg62_6"
                     /sec_met_domain="ILVD_EDD (E-value: 5.3e-26, bitscore:
                     79.9, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="HISPEAAAGGAIGLVKDGDIIEIDIPERTINVKVSDEELAERRKA
                     EEARGTKAFTPPHRQRVVSKALRAYGKMVSSADKGGVRVVED"
ORIGIN
        1 gtatttttag ttctttcgga tcggcagccg ctttcaaaat agccgtattg gaattgacga
       61 taatcgggaa cggtgtacga tccgttgcat cctgatggat gaaacggtgg aggtgaccac
      121 acaacataac gtccggcttg gcatcgcgta gcaaaggcat gaacttctgc tccacttcca
      181 agtttccatg ccatccgccg atcggtggga tatgggctac aataatttta aacggcgcgt
      241 ccttatattc tttgctatcc aatactcggc gcaaccattc ggcctgttct gtccggtatt
      301 cgtcgtagac tgttataccg gcatattcaa tatcggaatc cggcttgtcc tctcccgtat
      361 ccaaaacgac aaaacagatc ggaccttgcc ggaatgtata gtagatattc tcttcttttg
      421 gagagaaata acgttggaac tcggttgcaa aagcgccacg tgtttcgtgg ttgcctcttg
      481 tataatacat cggaatctca gaggcaaaca gcttggtcgc cgtatccata aaaccgtcga
      541 agatatgatt ttcctcattg aagactgaca ccatatcacc gttaaaaaga aaaaagtccg
      601 tctttttcaa atcacacttg gaaactaggt tcgtcaacag gtcatttttg ccatgtatat
      661 cgttcaccat cgcaaatgag acggaattat ccgcaggatc gctcgtcttg aacaccaacg
      721 gctttttgga gtaaacatca gtcgaggcat agttcccata gatgatctta tgtccgacat
      781 ggctcagtac ttcctgtacg aagacacgat aacggtagtt cgtacccggt ttaagccctt
      841 tgatcttcac ggtatggatc gtagatgtat tttttactcc gttacgggca tcataatatt
      901 tgggacgttc ggtagcataa aagttcgtat cgtcatccgg cgccagctcc acccaaccga
      961 cagaaggttt atccgacaac cacacgatcg tcacctcatc aggccctaga ttctgcaaat
     1021 aaggaccatg caccaaccga atcttcgact ctactgctcc tgctagacaa acagacagcc
     1081 acaataacat tactaaaatt tggaatttct tcatgatata atatttaagc aattaaattc
     1141 gaatttatag ctacgaagat atcgattact attcaaaaat ttcttatcaa aatgatacat
     1201 tttcattaaa aaaagtgaca attcataccg aattgccact ttctttatgc actcaaataa
     1261 aaaatgcgat gtctatcaat tgttttccgg gcgcaattta cgaacgactg cacctgcacg
     1321 ccacatttcg ctttcgcgca atgctgccag ttctttttcc aaaccttcac gataatccgg
     1381 cttactgttc gtatcgatag aacgctgcgc ttcgttaccg caggcgacct cccggtataa
     1441 tttttcaaat acaggcttaa cggcatcgtg gaacggcccc atccagtcta aagcgccacg
     1501 ctgtgcagta gtcgaacagt ttgcatacat ccagtccatt ccgttttcag caaacagcgg
     1561 catcaaagac tgagtcagtt cttcgactgt ttcgttgaat gcttcggaag gttcgtggcc
     1621 gttttcacgc aatgtttcgt attgagccaa caataaacct tggatagccc ccatcaaagt
     1681 tccacgttca ccagtcagat cggaataaac ttccttcttg aatgtcgttt cgaacagata
     1741 gcctgaacca acgccgatac ccaaagcgat cacacgatcc catgctctac cggttgcatc
     1801 ctggaaaatt gcatagcttg aattcaagcc acgtccctgc aggaacatac gacgcaaaga
     1861 agtaccagaa cctttcggtg cgactagaat cacgtcaaca tcagcaggag ggataatatt
     1921 ggtacgttcc ttgtaagtga tagcaaaacc atgagagaaa tacagcgctt ttcccggagt
     1981 cagatatttt ttgatacgcg gccagcattc gatctgagcg gcgtcggaaa gcaacacctg
     2041 tatgatagtt gctctttcgc aagcttcttc aataccgaac agtgtttcac ccggtaccca
     2101 gccgtcggca acagctttgt cataggtttt accaggacgc tgtcctacga taacgttgaa
     2161 accattatca cgcaagttca agctctgtcc aggaccttga acaccgtaac cgataactgc
     2221 aatcacttca tctttcaata cttctcttgc cttttccaac ggaaattctt cgcgggttac
     2281 tacgttttcg tcaacaccgc caaaattcat tactgccatt ttttctacta ttaaatgtaa
     2341 tgtgttaata aaataattct tttgtcagga cagttcgcaa accatccgcc cgtaccatgt
     2401 ttgttcaatg ccacataaca gcagcacggc aaatcgcttt gccttcatta cagatcgcca
     2461 tatcatattt tccgttatca gcctccctct tgtacaacat gagtttcatc ccatatttgc
     2521 cttcagactg gtaggcgatt tcgaaacgtt tgatatcttt tgtcttgaac aggtcaagat
     2581 caaacaggtc tagaagatgt tccatatact tgatactgtt caggtggccg ttgatatcaa
     2641 ggtcgctgta cttaatgaaa taaggaaccc cttccgtctc attctccaca gccgcaatct
     2701 ttcccggctt ttctatcggg caggggcgat ccgtgacata agcgctcaac ctggcgatat
     2761 ccaacaaggt cggccggcgt gtttccacat cgatagccgc ccaaatagaa cgggcgtaac
     2821 cgaatgtctt accgttgcca tccaccagct caaaacaacg gctggtaaag aggcggccga
     2881 cttcatccac ccaggtataa agagttatag gttcggacat ggctggatat tcgatcattt
     2941 cgatcgccag acgggaaaga acccaagccg tatgccgttc tgacatatcg ttgaaaccga
     3001 atccgcgttc agcagcatgg ctggatgcga catgtatcag atagtttccg atcatcggta
     3061 tcgttacacg tccacgaaaa tccaacaggt acggttccgt gacgaaatga aattccccta
     3121 ttttgctttt atctttatcc atgattcttt tctgttgggg cagttcgcaa accacccgta
     3181 cgttattttt tttcctgcaa cttacgttcc atttcggcca acatatcgct caaacgctcg
     3241 acacggcttt ttgtgatcgc aacgcgaccg gaacggatga actgcaagac accgatcgtt
     3301 tcgctcaact ccctgaaaag ggcttgcgtc tcatcgtaat gaccactctt ttcgagaacg
     3361 acacacgttt cgttcatttc cagaatacgg gcgttatatt tgcgaatcag atcctcgacc
     3421 gtccccatct tgataaacag ctcggtgctc agcttataaa gggcgatctc ctggaaaacc
     3481 agatcttcat ccgtattata gtaagccttc aagatatcca cccgtttgtc gatctgcttc
     3541 acaaccttgt cgatcatatc ttcatcggca aatgtcgtga ttgtaaattt atgtataccc
     3601 tgtatggcgg aaggtgaaac ggaaagcgtc tcgatgttca actgccgacg cgtaaagata
     3661 atcgtaatct ggttcagaag acctactgta ttctctgaaa agataataac ggtatataat
     3721 ttttttgttg tcatagcttc acctccttac ttatctccta atatcatgtt cgttacgctt
     3781 cctccggcag gcaccatcgg atataccata ccacacgttt ccacattggc gaccaacaca
     3841 aacgctccgt tatggttcaa catctcggca atagcctcat ccagttcctc ccgtttttca
     3901 acggtacggc cagcgatacc gtacgctttc gcgatcgcca cgaaatccgg gttctccatg
     3961 atcgtattcg aataacgttc gtggaagaac aactcctgcc actgacgtac cattcctaag
     4021 aaattattat tgaggataat gattttcaca tccagttttt cctgcataat ggttcccaac
     4081 tcctgaatcg tcatctgcat cccaccgtca ccggtaaaga agcagaccgt acggtcaggt
     4141 gcaccgaact tggctcccat agcagcggga aggccaaagc ccatcgtccc cagaccacct
     4201 gaagtaacca cgctacgagt gcgtttatat ttgaaatagc ggacacccat catctggttc
     4261 tgtccgacat ccgtaactaa aacagcatcg tttccggtcg cctcggacac ttttcgaacg
     4321 acttcaccca ttttcaaaga tccgttcatc ggatacaact ccttctcgat caccttttca
     4381 tactcttcct gtgcatccgg ctcaaactca gcattccact ccggacgttt ccgttcttcc
     4441 aacaacgcag ttatcatcgg aatggtatgt ttggcatttc cgagaacctt cacatcgacc
     4501 ggtacattct tcccgatctc cgagttgtcg atatccaaat ggatcacttt cgcctgcttg
     4561 gcgtatgtct tcaaatcacc tgtaacacga tcgtcgaaac gcataccgat ggcgatcaac
     4621 acgtcacatt cattggtctt cctgttcgga ccgacattgc cgtgcatacc caacataccc
     4681 ttattcaaag gaaaatcgga aggcaacgcc gatagaccga gaacagtcga accggcagga
     4741 atgtcattct tcaacaggaa tgctttcagc tcctcttcag cacctcccaa cagaacaccc
     4801 tgtccgacca ggcagaacgg tttctccgct ttattgatca acgcggcagc cgctttaatc
     4861 cgatcctggt tgatatccgg ttccggctga tagctgcgga tatagtctac tttcttatat
     4921 tcatactcta caaatccgac ctgagcatcc tttgccaaat cgagtacaac aggccccggc
     4981 cgtccggtag aagcgatata aaaagcacgt gaaacagccc acgctatctc ttccggcttg
     5041 cgaatctggt acgcccattt ggtgatcggt tgcgtaatgc cgatcacatc gacttcctgg
     5101 aaagcatctg ttccaagcaa tggagaaggg acctgtccgg ctatgaccac cataggcgtg
     5161 ctgtccatca gtgcatcggc aatgccggtg atggtatttg ttgcgccggg tcctgaagta
     5221 accaacgtca cccctacttt accggataca cgggcatacc cttgtgcagc atgcgtcgcc
     5281 ccttgttcat gacgcaccaa tacatgcttc aatttatccc tgtaatcgta caaactatcg
     5341 taaataggaa tcgcttgccc gccgggataa ccgaaaatcg tatctactcc ttcagctatc
     5401 agtgacttca gcaaagcttc cgaaccggtt atcttctgtt tctccatatc tctttatttt
     5461 agtcttgtgt ttaatcttct actactctca ctccaccctt atcggccgaa ctgaccatct
     5521 taccgtaagc tctcaaggct tttgagacga cacgctggcg atgaggcggc gtaaaggctt
     5581 ttgtgccgcg ggcttcttcc gctttacggc gttctgccaa ctcttcatcg cttaccttca
     5641 cattaatcgt acgttcaggg atatcaatct cgattatatc gccgtctttc accagtccaa
     5701 tcgctcctcc tgccgcagct tcgggagaaa tatg
//
