LOCUS       c00664_gnlPro..        11053 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IENNHJCG_664.
ACCESSION   c00664_gnlPro..
VERSION     c00664_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 13:01:49
            Original ID  :: gnl|Prokka|IENNHJCG_664
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11053
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11053
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[107:4720]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      108..4720
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..11053
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11053
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             108..524
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg664_1"
                     /sec_met_domain="Glyoxalase_4 (E-value: 2.1e-26, bitscore:
                     81.7, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGDVKIELLEPTSPESPIAKFIEKNNGNGGMHHLAFAVEDGVAGALAEVEEKGIRL
                     IDKAPRKGAEGLNIAFLHPKSTLGVLTELCEKPE"
     CDS             583..2136
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg664_2"
                     /sec_met_domain="CT_Btheta (E-value: 9.4e-292, bitscore:
                     956.9, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIDRRAAARLGGGEKAIAKQHEKGKYTARERIAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYIFAQDFTVSAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAQTEEEGLALIRKLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDNPN
                     KPYDMYEVIGAIIDNGEFLEIQKDYSKNIIIGFARFNGQSVGIVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKEQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRIIRALQQLQTKKLTNPAKKHGNIPL
                     "
     CDS             2168..3100
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg664_3"
                     /sec_met_domain="OAD_gamma (E-value: 7.6e-18, bitscore:
                     54.3, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLMLVLGFCSSCKEQKSNNKLLLNEVLVNNESNYQ
                     DDYGVHSAWIEIFNRSYGSADLAGCYLKFSSQPGDTASYFIPKGDVLTLIKPRQHALFW
                     ADGEPRRGTFHTNFKLDATNANWIGLYDSGKKLLDQVIVPAGTLKANQSYARVSDAADQ
                     WEVKGGSEDKYVTPSTNNKTIDSNAKMEKFEEHDSVGIGMAISAMSVVFCGLILLYISF
                     KIIGKISVNLSKRNAMKAKGITDKQEAKEKQLGQAPGEVFAAISMAMHEFQSDVHDVED
                     TILTITRVKRSYSPWSSKIYTLRETPHKK"
     CDS             3124..3558
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 67.3; E-value:
                     2.7e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg664_4"
                     /sec_met_domain="Biotin_lipoyl (E-value: 3.9e-22, bitscore:
                     67.3, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNVYKVAIGDIEDNIAHVEVNGTPYKVEMEKAPKVV
                     VKPVARPAATSAPAAPATPVVKPAAASTGKSGVKSPLPGVILDIKVNVGDTVKKGQVII
                     ILEAMKMENNINADKDGKITAINVNKGDSVLEGTDLVIIE"
     CDS             3560..4720
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg664_5"
                     /sec_met_domain="OAD_beta (E-value: 3.5e-153, bitscore:
                     498.9, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEFITFLGNNLADFWTYTGFANATVGHVVMLLVGLFFIYLAVAK
                     EFEPMLLIPIGFGMLIGNIPFNMEAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLVGAAAQFGIFGAYMIALAIGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRWLTSKNERLIRMKPPRVVSHTEKVMFP
                     IIGLLLTTFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDTITILLGLTVGAS
                     TQASEFLTLDSIKIFGLGALSFVIATASGVIFVKIFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             4890..6242
                     /locus_tag="ctg664_6"
                     /transl_table=11
                     /translation="MRKLFISLCFSACCSLLAAQTTNPIQEAMANYDYETALMLIDQET
                     PTVPLLYQKGKALKGLGNNLEALSVFQEVVAQDSLNPRAYIEAAECCKSLAKYSEALDY
                     YQNALHINPDNKYARIQYISLLMNMKRYRESLKESNLLAERDSSAYVLHLRAESMGQVY
                     DNTEIMHVIDAYLDIQKRYPNDYLSAAKLGNIYVAGHQYEDAINITEKYRSIDSTNVLV
                     NRINAQAYCLNKDYPKAIERYEQLLQEKDSSFQTCFYAGISYYALEDFYPAHDLLERAL
                     KDDNTNINVLYYLGRACSKTSWKEDGVTYLETAVSLAMPSDSVMSRLYVGLADCYKMAF
                     QYTDQANTLLTQYEKYDRQKHKLLYDAAFIYYYYLKDASKAERYLTAYLKTRPKNSKDK
                     VQEVDADGVPIIGEDNRYNAAENWLKDIREKRKKEDFFKGKVDTASVTPIK"
     CDS             6353..8203
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg664_7"
                     /sec_met_domain="Alpha-amylase (E-value: 1.6e-64, bitscore:
                     207.8, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVFLILGTLLLSLSTYAAMNVNKIDPPFWYTGMQNPELQLMVY
                     GEGIGNAAVSVNYPGVSLSSTVKLESNNYLLVYLKLDKDVKPGKFNLTFTEGKKKLVKE
                     YELKARNKKGCEHKGFDASDALYLLMPDRFANGNPDNDQIAGMAEYKIDRKDPNARHGG
                     DLAGIEQHLDYFSDLGVTALWFTPVLENNMTGGSYHGYATTDYYKVDPRFGTNEEYKQL
                     IEKAHARGIKIVMDMIFNHCGVEHVWIKDMPSKDWFNNPDHENNFVQTSFKLTPHVDPY
                     TSQYDADQMNDGWFVPSMPDLNQKNPHVYRYLVQNSFWWIEFANIDGIRMDTYPYADYD
                     AMSNWMKELNEEYPNYNTVGETWVTEPAYTAWWQKDSKLSAPKNSNLKTVMDFSFFDKI
                     NTAKNEQTETWFKGLDRIYNNFVYDFLYPNPASVLAFIENHDTDRFLGEGNNLPMLKQA
                     STLLLTTRRIPQLYYGTEVMMNGVKSKSDGYVRKDFPGGWTGDATNALTPAGRTKIQNE
                     CYDFYKTILNWRKGNDVIAKGSMVQFMVQNGVYAYARQYEGKTIFVMLNGTDAETTVPL
                     KFYKEILKDSKQGKDILSGKAITFGEELKMGPRESLVIEL"
     CDS             complement(8674..9684)
                     /locus_tag="ctg664_8"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTREMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCKHPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYEENVALTKKVVDYAHQFDVTVEGELGVLAGVEDEVSAEHHT
                     YTNPEEVIDFATRTGCDSLAISIGTSHGAYKFKPEQCHVDPATGRLVPPPLEFAVLDAV
                     MEKLPGFPIVLHGSSSVPQEEVDTINKYGGKLEAAIGIPEEQLRKAAKSAVCKINIDSD
                     SRLAMTAAIRKTFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSENKLAQLD"
     CDS             complement(9967..10974)
                     /locus_tag="ctg664_9"
                     /transl_table=11
                     /translation="MRKLLVLCSFWLCVATLGAQNAERKLYSVAFYNLENLFDTIHDAG
                     KNDYEFLPNGSYQWTAKKYESKLQNLSKVLGSLSRDLVPEGPAFIGVAEAENSRVLEDL
                     VKQPAISNYEFVHYEGPDRRGIDCALLYDPKQFSVTHSKLVLSTPFEGDTVHLTRGFLI
                     VDGQLAGERVCVIVNHWPSRGAKSPVRVHAARQVKALKDSLMRSDKKLKLIVMGDMNDD
                     PMDESMEVLGARKYPKQVKKGEFYNPWWVTLEDKGVGTLLYRGKWNLFDQIVISKPLLK
                     AKKGLRYDHNEVFIRDYLIQQDGKYKGSPLRTHGGRTWLNGYSDHLPTIIYLKN"
ORIGIN
        1 ataattaatt gcagaaaaat ttctttatta aacaagaatt gattttcttt gtgctgtttt
       61 ataccattcc gaaaagacga ttaataccaa aatttaaaaa tatagttatg aagatttcac
      121 acattgagca tctgggcatt gccgttaaga gcattgaaga agcccttccg tactacgaaa
      181 acgttttagg tttgaaatgc tacaacatcg aaaccgtgga agatcagaaa gttagaaccg
      241 ctttcctgaa agtgggcgat gtaaagatcg aattgttgga acctacttct cccgaaagcc
      301 caattgccaa gttcatcgaa aagaacaacg gtaacggtgg catgcatcat ctcgcattcg
      361 ccgttgaaga cggagtggcc ggtgcgcttg ccgaagtcga agaaaaaggt atccgcctta
      421 tagacaaagc tccccgcaaa ggtgcagaag gtctgaacat tgcattcctg catccgaagt
      481 caactctcgg tgtcctgacc gagctttgcg agaaaccgga ataagcaaga ctgtaaaatc
      541 atcaaatcat aaattgtata aacacttaaa gaatataaat tcatgagtaa tcaacttgaa
      601 aagattaaag agcttataga ccgccgcgct gcagcacgtc tcggtggtgg tgaaaaagcg
      661 attgcaaagc aacacgagaa gggtaaatat acagctcgcg agcgcatagc catgcttctc
      721 gacgaaggca gtttcgaaga aatggacatg ttcgtagaac atagatgcac caacttcggc
      781 atggaaaaga aacactaccc cggtgacggt gtagtaaccg gttgcggtac aatcgaaggc
      841 cgtctggttt atatcttcgc acaggacttc acagtttctg ccggttcact gtccgaaacc
      901 atgtctctga aaatctgtaa gattatggac caagccatga aaatgggtgc tccgtgtatc
      961 ggtatcaacg actcgggcgg tgcacgtatt caggaaggta ttaatgcctt ggctggctac
     1021 gctgaaatct tccaacgtaa catacttgct tcgggtgtca ttccgcagat ttccggtatt
     1081 ttcggtcctt gtgccggtgg tgccgtttac tctcctgcat tgactgactt tacgctgatg
     1141 atggaaggta catcctacat gttccttacc ggtccgaagg tagtaaagac tgtaaccgga
     1201 gaagacgtaa gccaggaaaa cctgggtggc gcgagcgttc actccaccaa atctggtgtt
     1261 actcatttta ctgcacagac agaagaagaa ggcttggctc ttatccgcaa actgttgagc
     1321 tacattcccc agaacaacct ggaagaagct ccttatgtag actgcacaga ccctattgac
     1381 cgtctggaag attccctgaa cgatatcatt cctgataacc cgaacaaacc gtacgatatg
     1441 tacgaggtaa ttggcgctat catagataat ggtgagttcc tcgaaatcca aaaagattat
     1501 tcaaagaata tcattattgg tttcgcacgt ttcaacggac agtccgtagg tatcgttgcc
     1561 aaccagccga agtatctggc aggtgtgctc gacagcaacg catcccgcaa gggcgcacgc
     1621 ttcgtccgtt tctgcgacgc cttcaatatt cctatcgtat cattggtaga cgtaccggga
     1681 ttccttccgg gaaccggcca ggagtacaac ggcgtcatcc tgcacggtgc caaactgctg
     1741 tatgcatacg gtgaagctac tgtacccaag gttaccatta cactgcgtaa gtcctacggt
     1801 ggttcgcaca tcgtgatgag ctgtaagcag ctgcgtggcg acatgaatta tgcttggcct
     1861 actgctgaaa tcgctgtaat gggtggtgca ggtgctgtag aagtattata tgcccgcgaa
     1921 gccaaagagc aggaaaatcc ggctcaattc ctggctgaaa aagaggctga atacaccaag
     1981 ttgtttgcca atccttataa tgcagctaaa tatggctaca ttgatgatgt tatcgaaccg
     2041 cgtaacacac gtttccgcat cattcgtgcc ctgcaacagt tgcaaaccaa gaaattgact
     2101 aacccggcta agaagcatgg taatattccc ttgtaatcaa gcttttcaca ctaaaacaag
     2161 aacgattatg aataaaacaa aaatcggaat attcctttca ttgatgctgg tgttgggctt
     2221 ttgctcttct tgcaaagaac agaaatcgaa caacaaactg ctgctgaatg aagtgctggt
     2281 caacaacgag agcaactatc aggatgacta cggtgtgcac agcgcatgga ttgaaatatt
     2341 caacagatca tacggcagcg ccgaccttgc aggttgctat ctgaaattca gcagccagcc
     2401 gggtgatact gccagttatt tcattcccaa aggtgacgtt ctgacactca taaaaccacg
     2461 tcagcatgca cttttctggg ctgatggaga accaagacgc ggtacatttc atacgaactt
     2521 caaactggat gccacaaatg ccaactggat tgggttgtat gattccggca agaaattgct
     2581 tgatcaagtc atagtgcctg ccggtacttt aaaagccaac caatcctatg cccgtgtcag
     2641 tgatgcagcc gaccaatggg aagtaaaggg tggaagcgaa gataaatatg tcactccgag
     2701 taccaacaac aagactatcg acagcaatgc caaaatggaa aaattcgaag agcatgacag
     2761 cgtaggtatc ggtatggcta tttctgccat gagcgttgta ttctgcgggc tgatattact
     2821 ctacatctcc ttcaagatta taggtaaaat atcagttaac ctcagcaaac gcaatgccat
     2881 gaaagctaaa ggtattactg ataaacaaga agcaaaagag aaacaactgg ggcaggctcc
     2941 gggagaagtt tttgctgcca tttcaatggc catgcacgaa ttccaaagcg atgtacacga
     3001 tgtggaagac acgatactta ccattacccg tgtaaaacgc agttactcac cgtggagttc
     3061 aaagatttat acgttgcgtg agactcctca caaaaagtaa gtcacccata ataaaataaa
     3121 acgatgaaag aatataaata taaaattaac ggtaacgtat ataaagttgc cattggagat
     3181 attgaagaca acatcgctca tgtagaagtg aacggtactc cctacaaagt tgaaatggaa
     3241 aaagcaccga aggtagtcgt taaaccggta gcacgtccgg cagccacatc cgctcctgct
     3301 gctcctgcta ctccggtagt aaaaccggcc gctgcttcta ccggcaagtc aggtgtaaaa
     3361 tctccgcttc ccggtgtaat cctcgatatc aaagtaaatg tcggcgatac agtaaagaag
     3421 ggacaagtta tcatcatttt ggaagccatg aagatggaaa acaatatcaa tgctgataaa
     3481 gacggtaaga ttacagccat caatgtaaac aaaggggact ctgttctcga aggtactgac
     3541 ctcgtaatta ttgaataata tgggagaatt tatcacattt ttaggaaaca accttgccga
     3601 cttctggact tatacaggtt ttgccaatgc aacggtagga catgtggtaa tgcttctggt
     3661 aggtttgttt ttcatatact tggctgtagc caaggaattt gagccgatgc tattaattcc
     3721 tatcggtttc ggtatgctga ttggtaatat acctttcaat atggaagccg gattgaaagt
     3781 tggtatctat gaagaaggtt ccgtacttaa tattctgtac cagggagtaa cctccggttg
     3841 gtacccgcca ctcatattcc tgggtatcgg tgccatgacg gatttctctg ctttgatatc
     3901 gaaccccaaa ttaatgttgg ttggtgcagc agcccaattc ggtatattcg gtgcttatat
     3961 gattgccctt gccataggat ttgacccgat gcaggctggt gcaatcggta tcattggtgg
     4021 tgccgatggt ccgactgcca tcttcctctc ttctaaactg gctcctaact taatgggtgc
     4081 cattgcggta tcagcctatt catatatggc attagtaccg gtgatacagc cgcctattat
     4141 gcgttggctg accagtaaaa atgaacgtct tatccgtatg aaacctcccc gtgtggtttc
     4201 acatacggaa aaagtaatgt tcccgattat cggtttgtta ctgaccacat tccttgtacc
     4261 atccggtctg cctttgctgg gtatgctgtt cttcggtaat ttactgaaag aaagtggagt
     4321 tacacgtcgt ctggcaaaca cagccagtgg tccgctgatt gataccatta ctattctgct
     4381 tggtttgaca gtaggtgctt ctacgcaagc atccgagttc ttaacccttg attcaatcaa
     4441 gatattcggt ctgggcgcct tatcatttgt cattgccaca gcatccggtg tcatcttcgt
     4501 gaagattttc aacctcttcc tgaagaaagg caacaagatt aatccgttga tcggtaatgc
     4561 cggtgtatct gccgtacccg actctgcacg tatctcccaa gtagtaggtc tggaatacga
     4621 tcctaccaac tatctgctga tgcatgccat gggcccgaac gttgccggtg taatcggttc
     4681 cgctgtagca gcaggtatcc tgctgggatt cttaatgtaa tacatttatt cattccgtta
     4741 tccggcttga attctgaact attttagagc cccttcattt ttggaggggc tttttcgtta
     4801 atctatctaa aacagattac gattatttcg taaatacatt ctttttagta acttgcagtc
     4861 agtttaacct catataaatg atatactgta tgcgaaagct ttttatctcc ttatgtttca
     4921 gtgcatgctg ttcgcttctg gcggcacaga ccacaaatcc cattcaagag gcgatggcca
     4981 actacgatta tgaaacagcc ttgatgctga tcgatcaaga aaccccgacc gtccccctgc
     5041 tctaccaaaa agggaaagcg ctgaaaggac tgggcaataa ccttgaagct ctgagcgtat
     5101 ttcaagaagt cgtagctcag gattctctca atccccgggc atacattgaa gctgccgaat
     5161 gctgcaaatc actagccaaa tatagcgagg cactggatta ctaccagaat gcgctccaca
     5221 taaatccgga caataaatac gcacgcatcc agtatatcag tctgctgatg aacatgaaga
     5281 gataccgtga gtctctaaag gaaagtaacc tgctggcaga aagggacagt tccgcctatg
     5341 tactacacct tagagccgaa agtatggggc aagtctatga caacacagaa atcatgcatg
     5401 tgatagatgc ctacctggac atacagaaaa gatatcccaa tgattacctg tctgctgcca
     5461 aactcggcaa catctatgta gcaggccacc agtatgaaga cgccataaac ataacggaga
     5521 aataccgttc catagactcc accaacgtcc ttgtgaaccg catcaatgcc caagcctatt
     5581 gcctgaacaa agattacccc aaagcaatag aaagatatga acaactgtta caggaaaaag
     5641 acagctcctt ccaaacctgc ttctacgccg gaatcagcta ttatgccctc gaagacttct
     5701 acccagcaca cgacctgctg gaaagggctc ttaaagatga caataccaac atcaacgttc
     5761 tctattatct gggacgcgcc tgctccaaga catcatggaa agaggatgga gtgacttatc
     5821 tggaaactgc cgtaagcctc gccatgccca gcgacagtgt catgtcccgc ctatatgtgg
     5881 ggcttgcgga ctgctacaag atggcatttc aatacaccga ccaggcgaat acccttctga
     5941 cgcaatacga aaaatacgac cggcagaaac acaaactgct ctacgacgca gcctttatct
     6001 attattacta tctgaaagat gcgtccaaag cagagagata cctaacggcc tacctgaaaa
     6061 cccgtccgaa aaacagcaag gacaaagtgc aggaagtaga tgcggacgga gttcccatca
     6121 tcggagaaga caaccgatac aatgccgccg aaaactggct gaaggacatc agagaaaagc
     6181 gcaagaaaga ggacttcttc aagggaaagg tcgataccgc cagcgtaacc cccatcaaat
     6241 agccccaatg aaaacgtttg cataatataa taaggtacag taacggagaa agattaactt
     6301 tctccgttat ttgttttaaa ttagcgcaaa aattaaccgt aaagttacta tcatgaaaaa
     6361 agtattctta atcttgggaa cactcttact ctccctcagt acgtatgcag ctatgaatgt
     6421 gaacaaaatc gaccctccgt tttggtacac cggcatgcag aacccggaac tccagctgat
     6481 ggtctatggc gaaggcatcg gcaacgcggc agtatccgtc aattatcccg gcgtctcatt
     6541 gagcagcacc gtcaagctgg aaagcaacaa ctacctcctg gtctatctga aactggacaa
     6601 ggatgtaaaa cccggcaaat tcaacctcac cttcactgaa ggaaaaaaga aactcgtaaa
     6661 ggaatatgaa ctgaaggcac gcaacaagaa aggttgcgaa cataaaggtt tcgacgcctc
     6721 cgacgcactg tacctgctga tgcccgaccg ctttgccaat ggcaacccgg acaatgacca
     6781 gattgcgggc atggccgagt acaagataga ccgcaaagac cccaatgcac gccacggcgg
     6841 tgaccttgcc ggcatagaac aacacctgga ctacttctcc gacctcggcg tcacagccct
     6901 ctggtttact ccggtactgg aaaacaacat gaccggcggt tcctatcacg gctatgccac
     6961 cacagactac tacaaggtgg acccgcgctt cggtaccaac gaagaataca agcaactgat
     7021 tgaaaaagcc catgcacgcg gcatcaaaat cgtaatggac atgattttca accactgcgg
     7081 cgtagagcat gtatggatta aggacatgcc ctccaaagat tggttcaaca accccgacca
     7141 cgaaaacaac ttcgtgcaga cctccttcaa actgaccccg cacgtagacc cttatacttc
     7201 ccagtacgat gccgaccaga tgaacgacgg ctggtttgta ccttccatgc ccgacctcaa
     7261 ccagaagaat cctcacgttt accgctacct ggtacagaac agtttctggt ggattgaatt
     7321 cgccaacatc gacggcatcc gcatggacac ttacccgtat gccgactatg atgccatgag
     7381 caactggatg aaagagctca acgaagaata tcccaactac aacaccgtgg gcgagacctg
     7441 ggttaccgaa cccgcctaca ccgcctggtg gcagaaggat tccaagctat cagcccccaa
     7501 gaacagtaac ctcaagaccg ttatggactt cagcttcttc gacaagataa acaccgccaa
     7561 gaatgaacag accgaaactt ggttcaaggg actggaccgc atatacaata acttcgtata
     7621 cgacttcctc taccccaacc ccgcttccgt actggcattc atcgaaaacc acgacaccga
     7681 ccgcttcctg ggcgaaggca acaaccttcc gatgctgaag caagcctcta ccctgctgct
     7741 taccacccgc cgcattccgc aactctacta cggaacggaa gtcatgatga atggcgtgaa
     7801 gagcaagagc gacggctatg tccgcaagga cttccccggc ggatggaccg gtgacgcaac
     7861 aaacgcactg accccagccg gacgtaccaa aatacagaac gagtgctacg acttctacaa
     7921 gaccatccta aactggcgca aaggaaacga tgtgattgcc aaaggcagca tggtgcagtt
     7981 catggtacag aatggtgttt atgcctacgc acgccagtac gaaggcaaga cgatattcgt
     8041 gatgctgaac ggtacagatg cagagaccac cgttcctttg aaattctaca aggaaatcct
     8101 aaaagacagc aagcagggaa aagatattct tagcggcaag gccatcacct tcggtgaaga
     8161 gctgaagatg ggccccagag aatcattagt gatagaatta taacgcgcac tccacacaga
     8221 gagctcattc ttgcaaatct cccttgcaga tagcttgcag acacctcgcc tgccagccat
     8281 ctgcaaggga tttttagtat ggaataggtg tcacggggat atgcttttca ccggtctcaa
     8341 atatagctaa tctgttagtt cataacggtg aacactttgt tccagtatag agaaacaaag
     8401 tgttcggata tgtagaaaca aagtgttctt acgtattgga acgaagtgtt tttgcatatt
     8461 ggaacgaagt gttctcttta ttgaaacaaa ctgttcagtt aagggaaaca gactgttttg
     8521 ttaaaggaaa cagactgttg tacacgttga aacatccgct tctgaaataa ccggcgaact
     8581 taaccatccc acaacaccgg cctatatata acaagtcagc ccttgcaaca tcaatattgc
     8641 aagggctgac gctatattcg gattatcttt cgattagtcc agttgagcca atttgttctc
     8701 tgaaccaagc acgttgatga ttttatgctt gtacagtttt tccatattgt cacgagccgg
     8761 acccagatac ttacgcgggt cgaattctgc cggtttttca gcaaatgtct tgcggatagc
     8821 agctgtcata gccagacgtg agtcagagtc gatgttgatt ttgcaaacag cagacttggc
     8881 agccttacgc aactgctctt cggggatacc gatagcagct tccagcttac caccatactt
     8941 gttgatagta tcaacttctt cctgaggaac tgaagaagaa ccgtgaagaa cgatggggaa
     9001 tcccggaagt ttctccatta cagcatccag aacggcaaat tccaaaggag gaggaaccag
     9061 acgaccggta gcagggtcaa cgtggcattg ttcgggtttg aacttgtatg caccatgaga
     9121 agtaccgatt gagatagcca gtgaatcgca acctgtacgg gtagcgaagt caataacttc
     9181 ttcaggatta gtatatgtat ggtgttctgc agaaacttca tcttctacac cggccaatac
     9241 accgagttcg ccttctacag ttacgtcgaa ctgatgggca tagtcaacta ccttcttagt
     9301 cagtgcaacg ttttcttcgt acggaaggtg tgaaccgtca atcattactg aagagaaacc
     9361 ggagtcgata cagctcttgc aagtttcgaa tgtatctccg tggtcaaggt gaagaacaat
     9421 ttcaggatgt ttgcaaccca attccttagc gtactcaaca gcaccctgag ccatgtaacg
     9481 caacagcgta gcgttggcat actgacgggc acccttagat acctgaagaa taaccggaga
     9541 ctttgtttca actgcagcct tgatgatagc ctgcatctgt tccatattgt tgaagttgaa
     9601 tgccggaata gcatatccac ctttgatagc cttagcaaac atctctcttg tgtttaccag
     9661 tcctaaatct ttgtaattaa ccattttgtt taaattttat tgttagtgaa ttaaaattct
     9721 acgcaaaagt aatcattatc ctttaaagta aagaacttga cgggaataaa atatccggct
     9781 catcctacca aatccattct attttaaagc tattggcttc atttaacaga ttattgtaat
     9841 ctctatatta caaactcttt gcatttatct ctgccagcca tacttttgcc atctatactt
     9901 ctatcaacaa aaaagccgga gaacatgttt gctctccggc atctgtttac acattattat
     9961 gtaatactaa tttttcagat agatgatggt cggcaaatgg tcactgtaac cgttcagcca
    10021 agtcctgccc ccatgcgtac gcaaggggga acctttgtat ttgccatcct gctgaatcag
    10081 ataatcgcgg atgaaaactt cattgtgatc atagcgcaac cctttcttag ccttcagcaa
    10141 cggtttcgaa atgacaatct ggtcaaacaa gttccacttg ccccgataga gcaatgtccc
    10201 cactcccttg tcttccagcg tcacccacca gggattgtag aattcgcctt tcttcacctg
    10261 cttcggatat ttgcgcgctc ccagcacctc catgctttcg tccatcgggt cgtcattcat
    10321 atcccccatc acgatgagct tcagcttctt gtcgctacgc atcagagagt ccttcaaggc
    10381 ctttacctgc ctggctgcat gcacacgcac cggcgacttt gccccacggg agggccagtg
    10441 gttcactatc acgcagacac gctctcccgc cagttgtccg tccacaatca agaagccacg
    10501 cgtcaagtgc accgtatccc cctcaaaagg agtggaaagc accaactttg agtgggtaac
    10561 gctgaattgc ttcgggtcgt acagcaaggc acagtcgatg ccccgtctgt ccggtccttc
    10621 ataatgcacg aactcataat tggaaatggc cggctgcttc acgaggtctt ccagcacccg
    10681 gctgttctct gcctctgcca caccgatgaa tgccggacct tccggcacta aatcacgcga
    10741 aagggacccc aacactttgg aaaggttctg cagcttggac tcatacttct ttgccgtcca
    10801 ctggtaactg ccgttaggca ggaactcata gtcattctta cctgcatcat gaatcgtatc
    10861 aaataagttc tcaagattgt agaacgcaac actatacagt ttccgttccg cattttgtgc
    10921 ccccagcgtt gccacgcaca gccagaaaga gcataagaca agtagtttcc tcataaattc
    10981 acaagattaa gtcctgcaaa aatcagaaat aaaatgcgat aaacctacta aataaaaata
    11041 aatctgaatt tat
//
