LOCUS       c00771_gnlPro..         9368 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IENNHJCG_771.
ACCESSION   c00771_gnlPro..
VERSION     c00771_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 13:01:49
            Original ID  :: gnl|Prokka|IENNHJCG_771
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9368
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1077
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg771_1"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.5e-48, bitscore:
                     152.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="ERPLVLVGQGVELGEAQQELRAFIEKAGMPAGCTLLGLSALPTDH
                     PLNKGMLGMHGNLGPNINTNKCDVLIAVGMRFDDRVTGKLETYAKQAKIIHFDIDPAEI
                     DKNVKTDVAVLGDCKETLAAVTQLLEPANHQEWIDSFRQYEEVEEEKVIRPELHPAGKA
                     LSMGEVVRAVSEATHNEAILVTDVGQNQMMSARYFKYSKERSIVTSGGLGTMGFGLPAA
                     IGATFGRPDRTVCVFMGDGGLQMNLQELGTIMEQKAPVKMILLNNNFLGNVRQWQAMFF
                     NRRYSFTPMMNPDYMKIASAYDIPARRVMTREELAKAIDEMIATDGPFLLEACVEEEGN
                     VMPMTPPGGSVNQMLLEC"
     protocluster    1..9368
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:3513]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1..3513
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..9368
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..9368
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             1110..1670
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg771_2"
                     /sec_met_domain="ALS_ss_C (E-value: 4.8e-20, bitscore:
                     60.8, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLYTIIVHSENFAGLLNQVTAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTDKDTIEKVTKQITKKIDVLQAHYFTDDEIYQHEIALYKITTPTLEEKPE
                     VSKVIRKYNARIVEVNAVFAIVEKNGMSEEITNLYEELRQLDCVLQFVRSGRVAITTSC
                     FERVNEYLADREAKYRQSKHQES"
     CDS             1667..2419
                     /locus_tag="ctg771_3"
                     /transl_table=11
                     /translation="MMSENNKIGTYKFVAEPFHVDFTGRLTMGVLGNHLLNCAGFHASD
                     RGFGIATLNEDNYTWVLSRLAVELDEMPYQYEDFSIQTWVENVYRLFTDRNFAIIDKEG
                     KKIGYARSVWAMISMNTRKPADLLALHSGSIVDYVCDEPCPIEKPSRIKVASKEPVAAL
                     VAKYSDIDINGHVNSIRYIEHILDLFPIEMYKEKRIRRFEMAYVAESYYGDELTLFMDD
                     AGEGVYDVEVKKNGSEVVCRSKVMFTEK"
     CDS             2470..3513
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg771_4"
                     /sec_met_domain="IlvN (E-value: 3.1e-47, bitscore: 149.3,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.8e-41, bitscore: 130.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGVIENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     ACNLRDNGFNVIVGQRPGKTYEKAVADGWVPGETLFGIEEACQKGTIIMCLLSDAAVMS
                     VWPTIKPYLTPGKALYFSHGFAITWNDRTGVVPPKDIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAVYQDATGKAFDKTIALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMT
                     PFHDAIKPVVQKLYASVKSGNEAQISIDSNSKPDYREKLNAELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             complement(3575..5488)
                     /locus_tag="ctg771_5"
                     /transl_table=11
                     /translation="MITFATMKEQDSNSPIIHLQQQQLLLRMEYEYEKEEFKRQTENMG
                     IARKVKRGLCWYPATPGRSYYNSLNQLVIEITHTENTDIEHNFEFGRPVCFFRQSADGK
                     ITYMNFTATVSYADETRMVAIMPGAGAVMEVQETDNLGVQLYFDETSYRTMFEALEDTL
                     RSKGNRLAELRDILLGTSKAGFRELYPVRFPWLNSTQETAVNKVLCARDVAIVHGPPGT
                     GKTTTLVEAIYETLHREPQVLVCAQSNTAVDWISEKLVDRGVNVLRIGNPTRVNDKMLS
                     FTYERRFENHPLYPELWSIRKNLRELGSRARRGSYDEREGVRSRMSRLRDRATALEIQI
                     NSELFDGAHVIASTLVSSNHRLLNGRRFGTLFIDEAAQALEAACWIAIRKADRVVLAGD
                     HCQLPPTIKCYEAARGGLERTLMEKVVSNKPAVVSLLKVQYRMHEEIMKFPSQWFYNGE
                     LEAASEVRYRGILDWDTPIHWIDTSEMDFKEEFVGETFGRINKAEADLLLSELKIYINR
                     ISGNRILEEKIDFGIISPYKAQVQYLRNKIKADASLKPYRSLFTVNTVDGFQGQERDVI
                     FISLVRANEEGQIGFLNDLRRMNVAITRARMKLVILGEAETLKHHGFYRKLLEFIQNIG
                     NQ"
     CDS             5603..7846
                     /locus_tag="ctg771_6"
                     /transl_table=11
                     /translation="MVYDLTMLKTFYAAYSEKIERVRNVLQRPMTLAEKILYAHLYDGD
                     KVKNYRRGEDYVNFRPDRVAMQDATAQMALLQFMNAGREQVAVPSTVHCDHLIQAYKGA
                     KEDIATATKTNEEVYNFLRDVSSRYGIGFWQPGAGIIHQVVLENYAFPGGMMVGTDSHT
                     PNAGGLGMVAIGVGGADAVDVMTGMEWELKMPRLIGVHLKGKLSGWVAPKDVILKLAGI
                     LTVKGGTNAIIEYFGPGTASLSATGKATICNMGAEVGATTSLFPYDERMGTYLKATGRE
                     EVAKMAASVAADLRADDEVLANPEKYYDRIIEIDLSLLEPYINGPFTPDAATPISKFAE
                     VVITNNYPRRMEVGLIGSCTNSSYQDLSRAASLARQVKEKNLKVASPLIVNPGSEQIRA
                     TAERDGMIAAFEDIGATIMANACGPCIGQWKRHTDDPERKNSIVTSFNRNFAKRADGNP
                     NTFAYVASPEITMALTIAGDLCFDPLRDTLVNAKGEVVKLSEPVGEELPAHGFIGGKEG
                     YIAPGKGQTEITVNPHSQRLQLLTPFPAWDGMDLLNMPLLIKVQGKCTTDHISMAGPWL
                     RFRGHLENISDNMLMGAVNAFNGETNKVWNRSTNTYGTVSGTAKLYKAEGIPSIVVAEE
                     NYGEGSSREHAAMEPRFLNVRVILAKSFARIHETNLKKQGMLALTFTDKADYDKIRERD
                     LISVMGLKDFASGRTLKVVLHHEDGSKESFEVQHTYNEQQIAWFRAGSALNAR"
     CDS             7850..9010
                     /locus_tag="ctg771_7"
                     /transl_table=11
                     /translation="MEKITVPFISGDGVGAEVTPSMQAVVNAAVRKSYGDRRGIEWKEV
                     LAGERAFHETGSWLPDETMEAFRTYKVGIKGPLTTPVGGGIRSLNVALRQTLDLYVCQR
                     PVRWYKGIVSPLKEPQKVDMCVFRENTEDIYAGIEWEAGTPEAEKFYRFLHDDMGVTKV
                     RFPETSSFGVKPVSREGTERLVRAACQYALEHHLPSVTLVHKGNIMKFTEGGFKKWGYE
                     LAECEFGKELAEGRLVIKDCIADAFLQNTLLIPEEYSVIATLNLNGDYVSDQLAAMVGG
                     IGIAPGANINYKTGHAIFEATHGTAPNIAGKDIVNPCSIILSAVMMLEYLGWKEAASLI
                     ENALEESFTEARATADLARFMPGGVSLSTSTFTREIVRRIENGNNE"
     CDS             9023..9367
                     /locus_tag="ctg771_8"
                     /transl_table=11
                     /translation="MKKEYLIYKLSEDLKEATRIENELFRKFDVKRGLRNEDGTGVLVG
                     LTQIGNVVGYERIPGGGLKPIPGKLFYRGYDVDDLAHAIIKEKRFGFEEIAYLLLSGRL
                     PDKEELSSFRE"
ORIGIN
        1 gaacggcctt tggtgctggt aggacaaggc gtggagctgg gagaagccca gcaagagctt
       61 cgtgctttca ttgagaaagc cggaatgcct gccggatgca ctttattggg actttccgca
      121 ttgcctacgg accatccgtt gaacaaagga atgcttggta tgcacggtaa cctggggccc
      181 aatatcaata ccaataaatg tgatgtcctt atcgccgtag gcatgcgctt tgatgaccgt
      241 gtgacgggta aattggaaac atatgccaag caggcgaaga ttatccactt tgatattgac
      301 cctgccgaaa tagataagaa tgtaaagact gatgttgctg tcctgggaga ttgcaaagag
      361 acactggctg ccgttaccca attgctggaa cccgccaacc atcaggaatg gattgacagt
      421 ttccggcaat acgaggaagt ggaagaggaa aaggtaatcc gtccggaatt acatccggca
      481 ggaaaagcgc taagcatggg tgaggtggtg cgtgctgtga gtgaggctac ccataacgag
      541 gcgatattgg tgactgatgt cggccagaat cagatgatgt ccgcccgtta tttcaaatac
      601 agcaaggaac gtagcattgt tacttccggt ggcctgggta ctatgggctt cggccttccg
      661 gcagctatcg gtgccacttt tggacgtccg gaccgcacgg tatgcgtatt catgggagac
      721 ggcggcttgc agatgaacct gcaggaactg ggtaccatca tggaacaaaa ggctccggtg
      781 aagatgattc tgttgaacaa taacttcctg ggcaatgttc gtcaatggca ggcgatgttc
      841 ttcaatcgtc gttattcgtt tactccgatg atgaatccgg attatatgaa gattgcttcg
      901 gcatatgata ttcctgcacg cagggtaatg acccgcgagg agctggcaaa agcgattgac
      961 gagatgatag cgactgacgg accattcctg ctcgaagctt gtgtggagga agaaggaaat
     1021 gtaatgccga tgacacctcc gggcggttcg gtcaatcaga tgttgttgga atgctgaagt
     1081 catgcgaaat taaagaattt actctatcta tggataaaaa actatataca atcattgttc
     1141 attcggaaaa ctttgccggt ttgctgaatc aggtgacggc tgtgtttacc cgccggcaga
     1201 taaacatcga gagtttgaat gtatcggcct cctccatcaa gggggtacat aaatatacca
     1261 ttaccgcttg gacggataag gataccattg aaaaggtgac caagcagatt accaagaaaa
     1321 tagatgtgct gcaagcccat tatttcacgg atgatgaaat ctatcagcac gagattgccc
     1381 tttataaaat aacgacccct acgctggaag aaaaaccgga ggtgtccaaa gtaatccgta
     1441 agtacaatgc ccgtattgtg gaggtgaatg ctgtatttgc cattgttgag aagaatggca
     1501 tgagtgagga aataaccaat ctttatgagg agttgcgcca gttggattgc gtacttcagt
     1561 tcgtccgttc gggtcgcgta gccattacga ccagctgctt tgagcgtgtc aatgaatatc
     1621 tggcggaccg tgaagcaaaa tatcgtcaaa gtaaacacca ggaatcatga tgagcgagaa
     1681 caataaaata ggtacctaca agtttgttgc cgaaccgttt catgtcgact ttaccggacg
     1741 gctgacaatg ggagtattgg gcaaccattt gttgaattgt gcgggtttcc atgccagcga
     1801 ccgcggtttt ggcatcgcga ctctaaacga ggacaattat acttgggtat tgtcccgtct
     1861 ggctgtcgaa ctggatgaaa tgccttatca gtacgaagat ttctccattc agacttgggt
     1921 ggagaatgtc tatcgccttt ttacagaccg taatttcgct atcatcgata aggagggcaa
     1981 gaagattggg tatgcacgtt ccgtttgggc gatgattagc atgaataccc gtaagccggc
     2041 agatttgctg gctcttcata gtggcagcat tgtagattat gtttgcgatg agccttgccc
     2101 gatagaaaaa ccttcgcgga taaaggtggc ctcaaaggaa ccggttgctg ctttggtagc
     2161 caaatacagt gatattgaca ttaacgggca tgtgaacagc atccgttaca ttgagcatat
     2221 ccttgatttg ttcccgatag agatgtataa ggagaagcgc atccgtcgtt ttgaaatggc
     2281 atatgtagcc gaaagctatt atggggatga gttgactttg ttcatggatg atgccggtga
     2341 gggcgtttac gatgtggagg tgaaaaagaa tggcagcgaa gtggtctgtc gctctaaagt
     2401 gatgtttaca gagaaataaa taaatttatc aacgttggcg taagccacaa ataaaaatta
     2461 aaacaaaaaa tggcacaatt gaattttggc ggtgttattg agaatgtaat gacccgcgaa
     2521 gaatttcctt tggaaaaagc acgtgagatt ttgaaagatg aaacaattgc agtaatcggt
     2581 tatggcgtac aaggcccggg ccaggcttgc aacttgcgtg ataacggttt caatgtgatt
     2641 gtaggacaac gtccgggcaa gacatacgaa aaggctgtgg ctgacggatg ggtaccgggt
     2701 gagactttgt tcggcatcga agaggcttgt cagaaaggta ctatcatcat gtgtctgttg
     2761 tctgacgcag ctgtaatgtc tgtatggccg actatcaaac cttatttgac tcccggaaag
     2821 gctctttact tctctcatgg ttttgctatt acctggaacg accgtaccgg cgtggttcct
     2881 cctaaagata ttgatgttat tatggttgct cccaaaggtt ccggtacttc acttcgtacc
     2941 atgttcctcg agggtcgtgg cttgaactca tcatatgccg tctatcagga tgctacgggt
     3001 aaggcttttg acaagacgat tgcactgggt atcggcatcg gttcgggata tttgttcgag
     3061 acaactttca tccgtgaagc cacttccgac ttgaccggtg aacgtggttc cttgatgggt
     3121 gctatccagg gattactgtt ggctcagtat gaggtattgc gcgaaaacgg ccatactcct
     3181 tctgaagcat tcaatgaaac agtggaagag ttgactcaat ctttgatgcc attgtttgcc
     3241 aagaatggta tggactggat gtatgccaac tgttctacta cggcacagcg tggtgcgctg
     3301 gattggatga ccccgttcca tgatgccatc aagccggttg tacagaaatt gtatgcaagt
     3361 gtgaagtcgg gtaacgaagc tcagatttct atcgacagta actccaaacc cgattatcgt
     3421 gagaagctga atgcagaatt gaaagccttg cgtgaaagcg aaatgtggca gacagctgtt
     3481 acagttcgta aacttcgtcc ggaaaacaat taatcagctt tatataaata ggtgaaatac
     3541 cctcttcggt gttaccggag ggggtatttc tttattattg attccctata ttttgaataa
     3601 actccaatag cttccggtaa aaaccgtgat gtttcagcgt ctctgcctct cccaatatca
     3661 ccagcttcat acgtgcccgg gtgatggcta cattcattct ccttaaatca ttcaggaatc
     3721 ctatctgccc ttcttcgttg gcacggacaa ggctgatgaa gataacatcg cgctcttgcc
     3781 cttggaagcc atccaccgta tttacagtga acaagctgcg ataaggcttg agtgaagcgt
     3841 ctgcctttat cttgttgcgg agatattgca cttgtgcctt gtaaggggag atgatgccga
     3901 agtctatttt ttcttccaga atgcggttgc cactgatacg gttgatgtag attttcagtt
     3961 ctgataggag caggtccgct tccgccttat taatgcgccc gaaagtctct cccacaaatt
     4021 cttctttgaa atccatttcg gaggtgtcaa tccagtggat gggggtatcc cagtccagga
     4081 tgccccggta acgcacttcg gaagcggctt ccaactcgcc attataaaac cattgggaag
     4141 gaaatttcat gatttcctcg tgcatgcggt attgtacttt cagcaaagag acaacggcag
     4201 gtttgttgga caccactttc tccatcaatg ttcgttccag acctccacgg gcggcttcgt
     4261 agcattttat ggtgggcgga agttggcagt ggtcacccgc caataccacg cggtctgctt
     4321 ttcggatagc tatccagcag gcagcctcta aggcctgggc tgcttcatca atgaaaaggg
     4381 tgccgaaacg gcgtccgttc agtagccggt gattgctgct taccagcgtg gaggctatga
     4441 catgtgcccc atcaaaaagc tctgaattga tttgtatttc caatgcggtg gcgcggtcgc
     4501 gcaggcggct catacggctg cgtactcctt cgcgttcgtc atagctgcca cggcgggcac
     4561 ggctgcccag ttcacggaga tttttccgga tgctccacag ttccggataa agcggatggt
     4621 tctcgaaacg acgctcgtag gtaaaggaaa gcatcttgtc gttgacacgg gtcggattgc
     4681 cgatacgcag gacattgacg ccacggtcca caagtttttc cgaaatccag tcgacggcag
     4741 tattgctttg ggcacatacc agtacctgcg gttcccgatg cagggtttca tagatggctt
     4801 ccactaaggt ggtcgttttt ccggttcccg gaggaccatg tacaatggcc acgtcgcggg
     4861 cacacagcac tttgtttaca gctgtctcct gcgtggagtt cagccaggga aaccgtacgg
     4921 ggtagagctc tcggaaaccg gctttcgagg ttcccagcaa tatgtcccgc aattcggcca
     4981 ggcggttgcc tttggagcgt aacgtatctt ccaaggcttc gaacatggtc cgataggatg
     5041 tttcgtcgaa ataaagttgc acgccgaggt tgtccgtttc ctgcacttcc ataacggcac
     5101 cggctccggg cattatcgct accatccgtg tctcgtcggc atagcttacg gtagcggtga
     5161 agttcatata ggttattttt ccatcggcag actggcggaa aaaacatacg ggacggccga
     5221 actcaaaatt atgttctata tcggtatttt ctgtgtgtgt aatttctatt actaattgat
     5281 tcagtgaatt atagtaactt cgtcccggag tggcaggata ccagcaaagt ccccgtttca
     5341 ctttccgggc aatccccatg ttttcggttt ggcgtttgaa ttcctctttt tcgtattcgt
     5401 attccatgcg cagcaaaagt tgttgctgct ggaggtgaat aataggacta tttgaatctt
     5461 gttccttcat ggttgcaaag gtaatcattc ttcacttccg acggaaaaaa tgctttattt
     5521 tgttaaacta ttcagccttt ttatttgttt atgatattaa tttgtaatct ttacaataat
     5581 gaaaaactaa aaaatagtgg ttatggtata tgatttaacg atgctcaaaa cgttttatgc
     5641 cgcttattcg gagaagatag aacgcgtacg gaatgtacta cagcgtccga tgactttagc
     5701 ggagaaaatt ttgtatgctc atttgtatga tggggataaa gtgaagaact acagacgggg
     5761 agaagactat gtgaatttcc gtcccgaccg tgtggccatg caggatgcaa cggcccaaat
     5821 ggccttattg caatttatga atgcaggccg tgagcaggtt gccgtgcctt ccactgtgca
     5881 ctgtgaccat ttgattcaag catataaagg tgcaaaagaa gatatcgcga ctgctacgaa
     5941 gaccaacgag gaggtctata attttctccg tgatgtttct tcccgctatg gcataggttt
     6001 ttggcagccg ggagcaggca ttattcacca ggtggtattg gagaactacg catttccggg
     6061 tggaatgatg gtaggcacgg actctcatac gcccaatgcc ggaggtttgg gcatggtggc
     6121 cattggtgtg ggtggtgccg atgcggtgga tgtgatgact ggcatggaat gggaattgaa
     6181 aatgccgcgt ctgataggcg tacacttgaa gggtaaattg agtggctggg tagctcccaa
     6241 agatgttatt ctgaagttgg cgggtattct tactgtaaaa gggggaacca atgccatcat
     6301 tgaatatttt ggaccgggaa ccgcttcatt gtctgccact ggaaaggcta ccatctgcaa
     6361 tatgggggca gaggtggggg cgactacctc ccttttccct tacgatgagc gcatgggtac
     6421 ttatttgaag gctaccggac gtgaagaagt ggcaaaaatg gctgcttccg tagctgccga
     6481 ccttcgcgcc gacgacgaag tgctggcaaa tccggaaaaa tattacgacc gcatcattga
     6541 aatagacctc tcgctgttgg aaccgtatat caatgggccc tttacgccgg atgcagcaac
     6601 accgatatcg aaatttgccg aggtagtgat aaccaataac tatccccgcc ggatggaagt
     6661 cggcctgata gggtcgtgta ccaattcgtc ctatcaggat ttgagccgcg cagcctccct
     6721 tgcccggcag gtaaaggaaa agaatttgaa ggttgcttct ccgctgattg tcaaccccgg
     6781 ttcggagcag atacgtgcca ctgctgaacg cgacggcatg attgccgctt tcgaagatat
     6841 tggcgcaacg ataatggcga atgcctgcgg accttgtatt ggccagtgga agcgccatac
     6901 tgatgaccct gaacgaaaaa attccatcgt cacctctttt aaccgtaatt ttgccaaacg
     6961 tgccgatgga aatcccaaca cttttgctta cgtcgcttcc ccggagataa cgatggcgct
     7021 gaccattgcc ggtgaccttt gtttcgaccc gttgagggat acgctggtca atgccaaagg
     7081 agaggttgtg aaactgtccg aaccggtcgg tgaagaactg ccggcacacg ggtttatagg
     7141 aggaaaggaa ggatacattg ctccaggcaa aggacagacg gaaattacgg tcaatcctca
     7201 ttcacagcgc ttgcaactgc tgactccctt ccctgcctgg gatggcatgg acttgctgaa
     7261 tatgccctta ttgattaaag tgcaagggaa atgtaccacc gaccacatct ctatggcggg
     7321 gccatggctc cgtttccggg gacatttgga gaatatttcg gacaatatgc tgatgggggc
     7381 tgtcaatgct ttcaatggag agacgaacaa ggtttggaac cgctccacca atacctatgg
     7441 aacagtgtca ggcactgcga agctgtataa ggccgaaggt atcccttcca ttgtcgttgc
     7501 cgaagagaat tatggtgaag ggtccagccg tgagcatgct gccatggaac cacgcttctt
     7561 gaatgtacgc gtcattttgg cgaaaagctt tgcccgtatc catgagacga atttaaagaa
     7621 acaaggcatg ttggcactga cctttacgga taaggccgat tatgacaaga ttcgggaacg
     7681 cgacctgatt tctgtcatgg ggttgaaaga ttttgcttcg ggacgtacgt tgaaggtggt
     7741 tcttcatcac gaggacggga gtaaagaaag ttttgaagta caacatacgt ataacgaaca
     7801 gcagatagcc tggttccggg ccggttctgc acttaatgca agatagaata tggaaaaaat
     7861 tactgtacct tttatttccg gcgatggagt gggagcagaa gtgaccccat ccatgcaggc
     7921 tgtcgtgaat gccgctgtca ggaaatccta tggtgaccgg cgtggcattg aatggaaaga
     7981 agtgctggca ggagaacgtg ctttccacga aaccggctcc tggctgccgg atgaaacgat
     8041 ggaagccttc cgcacttata aggtgggcat caaaggtcct ttgacaacac ctgtcggcgg
     8101 aggtatccgt tcgttgaacg tggcattgcg tcagacgctt gatttgtatg tctgccaacg
     8161 tccggtacgt tggtataagg gtattgtttc tccactcaaa gagccgcaga aggtggatat
     8221 gtgcgtattc cgtgagaata ccgaggatat ttatgcaggc atcgaatggg aagccggaac
     8281 tccggaggct gaaaagttct atcgttttct ccatgatgac atgggggtga caaaagtccg
     8341 ttttcccgaa acctcctcgt ttggcgtgaa gcccgtttca agagaaggaa cagagcgctt
     8401 ggtgcgtgcc gcctgccaat acgcgcttga gcatcatctg ccttccgtga ccttggtaca
     8461 caaaggaaac atcatgaaat ttacggaagg cggtttcaag aagtgggggt acgagctggc
     8521 agaatgtgag tttggtaaag agctggcaga agggcgtctg gtcatcaagg actgcattgc
     8581 cgatgcattc ttgcagaaca cgttgcttat ccccgaagaa tattccgtga ttgccacgtt
     8641 gaatctgaac ggtgattatg tgtccgacca actggctgcc atggtaggcg gcatcggcat
     8701 tgcaccgggt gcgaatatca actataaaac ggggcatgcc atttttgagg ctactcacgg
     8761 gacggctccg aacattgccg ggaaagacat tgtgaatccc tgttccatca tcctttccgc
     8821 tgtgatgatg cttgaatatc tgggttggaa ggaagcagcc tctcttatag agaacgcctt
     8881 ggaggaaagt ttcacagaag cccgtgctac tgccgacttg gcccgtttta tgccgggtgg
     8941 cgtctcgctg tccacttcga ctttcacccg ggagattgta aggagaatag aaaatgggaa
     9001 taacgaataa aacgaaacga ttatgaagaa ggagtatctg atttacaagc tttccgaaga
     9061 tttgaaggaa gctacccgga ttgagaatga actgttcagg aagtttgatg tgaagcgcgg
     9121 tttgcgtaat gaggacggca cgggagtctt ggtggggttg acccaaatag gcaatgtggt
     9181 cggctatgaa cgcatccccg gtggagggct gaagcctatt cccggcaaat tgttctaccg
     9241 cggttatgat gtggatgact tggcacacgc catcatcaaa gagaagcgtt tcggttttga
     9301 ggaaattgcc tacttgttgc tttccggtcg cctgcccgac aaggaagaac tctcttcttt
     9361 ccgtgaac
//
