LOCUS       c00011_gnlPro..        16497 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MFHNKMOJ_11.
ACCESSION   c00011_gnlPro..
VERSION     c00011_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 07:59:11
            Original ID  :: gnl|Prokka|MFHNKMOJ_11
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16497
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16497
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2018:6497]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2019..6497
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
     cand_cluster    1..16497
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /kind="single"
                     /product="Glycine_cleavage"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16497
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Glycine_cleavage"
                     /region_number="1"
                     /rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T, GDC-P,
                     SoxG]) and GCV_H and GCV_T_C)"
                     /tool="gutsmash"
     CDS             65..763
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S11"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg11_1"
                     /sec_met_domain="Peptidase_S11 (E-value: 6.6e-54, bitscore:
                     175.3, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDALTGKVLFSHNGLQHRQVASTQKLVTAMVVMEHGSLDKKVVIQ
                     PSDTKADPTKLGFRAGEVYSRRELLNAMMIRSFNDVALALARDTAGSVPRFAQLMNAKA
                     RQMGMYNSRFANPNGLPADQYSTAIDMARCAYYVYRNPELRNIICKRQYAFTRANGRTL
                     LLRNTNKLLTQNPWVTGMKTGYTNAAGRCLVSSAGVNGRHVIVVVLGCHPSRIWTESEN
                     LIRWALGYAV"
     CDS             822..1943
                     /locus_tag="ctg11_2"
                     /transl_table=11
                     /translation="MLQAGIVGLPNVGKSTLFNAVTRTRKAQAANYPFCTIDPNVGMVT
                     VPDPRLQVLSDMSGSEKIIPTLIEFVDIAGLVKGASEGAGLGNQFLANIREVDAIVQVV
                     RCFDNDDIIHELGSVNPLRDIDIINSELILADIATMEKRLSSRERKARSGDKEAKAEVA
                     LITKLLPHLNEGNPALTLEPQLDDDERKLLHSFQLLSDKKSIFACNVNEDELADAISNP
                     DAHPYVSQVKKYVAEHHNAEAIVISARIEEELIDVSEEESREFLESLGVRDSGVSDLIR
                     AVYHLLGLRTYLTTGIKETRAWTIPSGAKAPQAAGVIHTDFERGFIAAEVVHYDDLVSC
                     GGKAGAREHGKLRIEGKEYVVKDGDVIEFRFNV"
     CDS             2019..3104
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_3"
                     /sec_met_domain="GCV_T (E-value: 1.3e-87, bitscore: 285.9,
                     seeds: 72, tool: rule-based-clusters)"
                     /sec_met_domain="GCV_T_C (E-value: 1.1e-22, bitscore: 72.2,
                     seeds: 348, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTDVKSTPLAAKHVELGARMVPFAGWNMPVQYTGILDEHKAVR
                     ETCGIFDISHMGQFTVAGDSAAAWLNSMLTNDINKLNVGQGQYSVMLNDRAGVIDDLIL
                     YRMEPETFFVVVNASKIDEDFAWLSAHQPAGVTLENHSDEYVGLAVQGPECGEVFSRVI
                     PGVELPPRNGISRISAEGTDLIVCRTGYTGEDGFEFFCPAKEGVKWFEAFLGAGAKPCG
                     LGARDSLRLEMCYPLNGSDLSPDKTPLEAGLGFFCALDTDFIGSDILREQKANGLSQRL
                     AAIEYTGKGAPPRAHYAVHVPGGEAIGELTSGVLSPSLMKGIALAYLPAAHAKVGTELE
                     IDVRGRKFPAVVVKKPFYKKG"
     CDS             3175..3555
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_H"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_4"
                     /sec_met_domain="GCV_H (E-value: 1.4e-47, bitscore: 153.0,
                     seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDVPENLLYSKDHEWIEIDGDIGTIGISDHAQAELSDVVFVDLP
                     EVGATVAAGDPVAVVESVKAASDVYTPVSGEILEVNEELSNDPSLINSDPYGAGWLYKI
                     RLDVPTETEDMMNATDYEEYCS"
     CDS             3651..6497
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GDC-P"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Beta_elim_lyase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_5"
                     /sec_met_domain="Beta_elim_lyase (E-value: 2.5e-10,
                     bitscore: 32.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="GDC-P (E-value: 1.2e-178, bitscore: 586.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTHSDFASRHIGPQGEERREMLDSLGYRTLDELIADIVPADIRM
                     KAPLDLPAAKSETEALEELRSILRKNKLLKTFIGQGYYGTITPSVILRNVLENPGWYTA
                     YTPYQPEIAQGRLEMLMNFQTMVSSLTGLPVANASLLDEGTAAAEAVTMCRNARPKANT
                     FFVADTCHPQTISVIRTRAAFQGVNIIVGDCSSFDPASIGADLAGVLVQYPDTLGRICD
                     YTDFFSRVHATGALCVVAADLMALTVIREPGAFGADICIGNTQRFGIPMGFGGPHAAYM
                     SCTDALKRRMPGRLIGMSIDTLGRPAYRLALQTREQHIRRDKATSNICTAQVLLAVLAA
                     FYAVYHGQEGLKRIGTEIHLKTKSLYKALTEAGIAIKNKNFFDTLLLSVPGQADAMVQK
                     ALEAGYNIRRVDADHAAISLDETATCADIAALASALAGAETSAACDCDAPAWDPVHTRQ
                     TPFCTEKAFNSYHSETEMMRYIRRLESRDLALNEAMIPLGSCTMKLNAASEMIPITWPE
                     ANSLHPFVPADQSEGIREMLSVLSDRLAKITGFAAVSLQPNAGAAGEYAGLLAIRRYQK
                     HAGEGHRNVCLIPTSAHGTNPASSAMAGLKVVPVKCDERGNIDMADLKSQAEAHKDNLS
                     CIMVTYPSTHGVYEQTIKELCDIVHANGGQVYMDGANMNAQVGLTCPGCIGADVCHLNL
                     HKTFAMPHGGGGPGIGPIGVAEHLVPFLPGHLTLGHEEGAVASAAWGSASIAAICWMYL
                     SMMGPDGLREATEMAILNANYIAKKLGHLFPVLYSGNKGLVAHECILDPRQLTHDAGLT
                     VDDIAKRLMDYGFHGPTMSFPVPGTLMVEPTESEPKKELDRFIEAMERIHAEITAIING
                     TADKEDNVLKNSPHTAEMVSADEWRHPYSRSEAAYPVSGLLIHKFWPYVGRVDNVYGDR
                     NLVCTCDTVEEFSKAVEL"
     CDS             6853..7818
                     /locus_tag="ctg11_6"
                     /transl_table=11
                     /translation="MIFHHVFGLYALPAGVDTAWIAPQLTKAAPIFKICVPIFIFITGY
                     AMGWKTNSSPTFGSLIKTGFSHYFKFWKIYFLCLLLAILVSWAFPLPILPSVADMGWKN
                     GLLVVTGLRPCYPDWWYMALFAAATMALYPICAWITHHIAPVPSMAALLGVSLLFQSTA
                     HIPSLPGIAYSFPPFLPCFILGYMCAFLASRLSALSISQSLGAILLLALEILSIHLFSF
                     SKAKTLTVIFLFTLWCLPWITRKLRLTPLLTLLGTYSALMWLNHRFIFGYHFSWDLYGT
                     QSISVVFIVTLVSSLLLAMAMQKLFNRMIPSNPQTQSKTL"
     CDS             complement(7850..8482)
                     /locus_tag="ctg11_7"
                     /transl_table=11
                     /translation="MSDLYEYQAIDGSSKGPVDLVLLLRARNLGRLSNRTLVRKVPGGD
                     WRPLASFIPSMTVMDDDGEPSVLPDPGSEPGGADSGWSRKKYWIRVIKAWCRFEGRAGK
                     GELHEVFSRVGVAWLAVAGVPSFAECGFFPSLVPWVELVSPLLYVVLAVLSIPLAATMV
                     RRLHDVGRSGFFLVFLAVPFIGWLLLWYLSHGESRIGENKYGDPPWN"
     CDS             complement(8491..10599)
                     /locus_tag="ctg11_8"
                     /transl_table=11
                     /translation="MGASGQATKPAARSVKTSKPNVIFILVDDMGWGDLDSNWSQQKLN
                     GRTVERKNEFKTPALSALAREGIQLRRHYSAAPVCAPARASLLLGVHQGNSRVVRNNRF
                     DQPIEDSHTLGTVMRDAGYDTAAIGKWGVGGGGQSHVPMTAGPHQRGFNYFYGILDHLA
                     GHFHYPSESRDVFEYNGYASNPEWKNIKDQVPQTAYSTDLFAARAKQWIVDQRKFARKT
                     GKPFFLYLAFPAPHGNLVVPGVPYPSGGGLKGGLQWVKKEGTESVNTAFDAKAEKNKDT
                     YIHPDNSRFPNDVAKRHSTMIRRVDDAVADLIRLLKDLKIDDNTMIVFSSDNGPHNEGG
                     ADSRHWHGAQNPQFFKSYGMMDGIKRDCWEGGMRVPTLVRWPARIPKGQISLHPGQFHD
                     WLATLADVAEVPVPARSDGVSLLPTLTGHADQQKPGIVYAEYNFAGKTPEYKDFLGEHK
                     GAQRGQQQIVFVDGLKGLRMGVKDADKDFMIFDTLNDPQESKDLASSKPELQARMKAAA
                     LSNRRASLPSKTVFDSALVPAVDVKGTVSPGLRWALYEGDFPWVPDFRQWKKPASAHGV
                     TPSPSVKMNGSDKRGVELTGYVKIPEDGAYTFYLTTDENKGSKAFVRLHGMELIDADKT
                     YEPGAEVSSDLGDRKNPVYLKAGLHPIRIGYVGNSGTASKLVLKWEGPGLSKKEIPASA
                     FSHGKESR"
     CDS             complement(11069..12925)
                     /locus_tag="ctg11_9"
                     /transl_table=11
                     /translation="MFSFFRDFDRSFFPMTQTSSFSALGISPEILEAIEVLGFDTPSSI
                     QEQAIPAAISGADIVGLSHTGSGKTLAFAIPALECIEPEERCVQVLALCPTRELAVQIC
                     REVDKLALFMDGVSAVPIYGGASFRPQLDALRRGVQFVVGTPGRVMDLMESGALRLDGL
                     RMLILDEADEMLDMGFLEDIERIAEAMPETKQTLFFSATMSPEINRLVSRFMKEPIQIS
                     IERPTLTVPTIEQVYYEVVFSSRIEVLSRLLDTGKIKMGLVFANTKKVVDDVVDGLTAR
                     GYPVDRLHGDMPQMMRERVMDSFRKGSLRLLVATDIAARGLDVDDVDAVVNFELPRDPE
                     DYVHRIGRTARAGRKGKAITFVGRRDFSLMSRIERFIGVKLTPEPVLTAVQVDQLRTES
                     LVDDILERLKPDAVLPEELKEVEAAPEAMAAALFDLLRERTHREVQPIPEDKPARRARR
                     MPQTGEEAESPQKGDSWQHKGDTVTLFMNGGRMIGLRPKDIAGLFYNTVEMEKGAVGDI
                     RIFPKHSLIEVDASVAPLLLEALATATVCGYEVNVREDKGAPEYSGTPRSSRRNGGFRN
                     SYRGERDRSDRSGFRGNRGGFRSDRGERWGERSRRDDRKKRF"
     CDS             13075..13878
                     /locus_tag="ctg11_10"
                     /transl_table=11
                     /translation="MIQIFPSEFMDKTPNKSQSSLLGIFINILLPVLILDYCSAGPANP
                     LERPEGENFWHIGPVWALVIALSLPLVYGIRSLVVSRKFDLMSVVGMAGVLLTGVISIF
                     VIGPEGRIHSATPWLFAGKEALIPLILAAAVVVSRSAGTPLLNMFIYTPELFDVRRIEQ
                     TVAANGEERAYQKLLANSSWILAGTLVASSIGNFFLSLSFMSSVIQQPEAEQQVAYNAA
                     IGSITWWGFLIIGIPILAALVFIMTRLIKRLGRLTGLSRDELLLK"
     CDS             13889..15427
                     /locus_tag="ctg11_11"
                     /transl_table=11
                     /translation="MRLHTSCILAAAIALHAAWADTPRFDRVFGSHMVLPHGKNIPVSG
                     TAAPNREITVTFGNTALKTKTDSKGKWSVTLPPMPPCATGQTLAAVQNGDSAKLEDVLV
                     GEVWLASGQSNMLFRLNQTTTAKEDIAASGDDQLRLLNNVPQAHTNNAPYSAKDFDAVT
                     TDNFYKGQWAASSPATSGPMTAVGYYFGKKLREGLGIPVGIIHSSLGGSEIAAWIPRQV
                     INANNSFRTLRGNHWLDSPLISDWVRGRARKNISPRLNQGSPDHPYKPAFLYESGIAWT
                     TALPITGVIWYQGESDAEIIDNAQNSMLLKTMISSWRKAFRNPEMPFVMIQLPRINDPS
                     KIRAGWPEFREMQDAVAKTVPKVYSVNTIDLGSTNSDVHPPFKRPVGERAGNTALNKVY
                     GKKIPCEGPALKAFKPSGSNILVQLDQAAGLTTTDGKEPAQFEIAGTDGTYHPAAAEII
                     NRKGNTAVIRLSSPEVKSPKHARYCWNRFVTPNLVNGNQLPARPFRTDEPVLKK"
     CDS             15449..16426
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg11_12"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 2.4e-26, bitscore:
                     85.7, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLHLILASLTATLSLGIAAQAAPAKVACVGDSITFGTGLKPGET
                     RYPQVLATLMGPDFDVRGFGNPGKTAGDYPGQAGRWYGSTREHKQALEFKADIYICNLG
                     INDTGRWWNPELFSKGYDALLHAWKNANPKTRFFAWGLLGPDYRGPLNKKAFPGNCYPD
                     VRKYAGSDNGSSANRPEAEKLIAAVARKYKVSLFDALHPLSDHPEWYVDGLHPTEQGAR
                     RIAEITFAKLAKSLRLKQPAPRLEPGTGNVIINNPGNSGILLDGWKLTDGTNTLIFENS
                     TVIHPKDRLIIAIGPETQKDPTKPLQIKSSQSPAAFRLIPAKKY"
ORIGIN
        1 cacacgccct gtagccatcc cctcaagcgc cccgcgcacg ccccgctgcg ccagtgcctg
       61 cgtcatggac gcccttaccg gcaaagtgct cttttcccac aacggcctcc agcaccgcca
      121 ggtagccagc acgcagaaac tcgtgacagc catggtcgtg atggaacacg gcagcctgga
      181 caaaaaagtg gtcatccagc cttccgatac caaggcggac cccaccaaac tgggattccg
      241 ggcgggggaa gtctattcac gccgcgaact gctcaatgcc atgatgatcc gcagtttcaa
      301 cgacgtagcc ctggcgctgg cccgcgatac ggcgggttcc gttccccgtt tcgcccagtt
      361 gatgaatgcc aaagcccggc agatgggcat gtacaactca cgcttcgcca atcccaacgg
      421 cctcccggca gatcaatatt ccactgccat tgacatggcc cgctgcgcct attacgtgta
      481 ccgcaacccg gaactgcgca atattatctg caaacgccaa tatgccttta cccgcgccaa
      541 cggcagaacg cttctgttga gaaacaccaa caagctgctc acccagaacc cctgggttac
      601 cgggatgaaa actggataca cgaacgccgc cggacgctgc ctggtttcct cagccggcgt
      661 caacgggcgc catgtcatcg tcgtcgtcct cggctgccat ccgtcccgta tctggacgga
      721 atcggaaaac ctgatcagat gggctctggg atacgccgta taaatgcccg tcggcaattg
      781 gtatttgact ttcacggcgt gacccgctat cagtcctgcc tatgttacag gcaggtattg
      841 taggtctccc caacgtcggc aaatccactc tattcaatgc ggtcacccgg acgcgcaagg
      901 cccaggcggc caactatccc ttctgcacca ttgacccgaa cgtgggtatg gtaacagtcc
      961 cggatccccg cctgcaggtt ctttccgaca tgtccggttc tgaaaaaatc atccccacgc
     1021 ttattgaatt cgtggatatt gccggcctgg tcaagggcgc ctcggaaggc gccggcctgg
     1081 gcaaccagtt tctggcgaac attcgtgaag tggacgccat cgtgcaggta gtccgctgct
     1141 ttgacaatga tgatatcatt catgaactcg gttccgtgaa tcctctgcgc gacattgaca
     1201 tcatcaactc ggaactcatt ctggcggata tcgccaccat ggaaaagaga ctctcttccc
     1261 gcgaacgcaa ggcacgcagc ggcgacaagg aagccaaggc cgaagtggcc ctcatcacca
     1321 aactcctgcc ccacctgaac gaaggcaatc ccgccctcac ccttgaaccg cagctggacg
     1381 acgatgaacg caagctgctc cattccttcc agctgctttc ggataaaaaa agcattttcg
     1441 cctgcaatgt caatgaagac gaactggcgg acgccatctc caacccggac gcccatccct
     1501 acgtctccca ggtgaaaaaa tacgtagcgg aacaccacaa cgcggaagcc attgtcatct
     1561 ctgcccggat tgaagaggaa ctcatcgacg tctcggagga agaatcccgc gaatttctgg
     1621 aatccctggg cgtgcgggat tccggcgttt ccgacctcat ccgggccgtg taccaccttc
     1681 tgggcctgcg cacctacctc accacgggaa tcaaggaaac gcgggcctgg accattccgt
     1741 ccggggcaaa agcacctcag gcggccggcg ttatccacac ggactttgaa cgcggtttta
     1801 tcgccgcaga ggtagtgcac tacgacgacc tggtttcctg tggcggcaag gccggagcga
     1861 gggaacacgg caagctgcgc atcgaaggaa aagaatatgt cgtcaaagac ggggacgtta
     1921 tcgaattccg cttcaatgtc tagacggaag cgttaccgga attccattga cttttactga
     1981 tataaggagc agattgctca caaccttcac atcgcctcat gactgataca gacgtcaaat
     2041 ccacccccct ggcagctaaa cacgttgaac tgggagccag aatggttcct tttgccggct
     2101 ggaatatgcc ggtgcagtac accggcattc tggacgaaca caaagcagtg cgcgaaacct
     2161 gcggcatctt tgacatctcc cacatggggc agttcacggt agccggcgat tctgccgcgg
     2221 cctggctgaa ctccatgctg accaatgaca tcaacaaatt gaatgtaggg caggggcaat
     2281 actccgtcat gctcaatgac agagccggag tcattgacga ccttatcctg taccggatgg
     2341 aaccggaaac cttcttcgta gtggtgaacg cctccaagat tgatgaagac ttcgcatggc
     2401 tttccgccca tcaacctgca ggcgtaaccc tggaaaacca ctccgacgaa tacgtggggc
     2461 tggctgttca aggtcccgaa tgcggagaag tattctcccg cgtcatcccc ggtgtggaac
     2521 ttcccccccg caatggaatt tcccgcatct cggcggaagg gacggatctc attgtctgcc
     2581 gcaccggcta taccggggaa gatggttttg aattcttctg cccggctaag gaaggcgtca
     2641 aatggtttga agcctttctt ggagcaggag ccaaaccctg cggcctgggc gcccgcgaca
     2701 gtctgcgtct ggaaatgtgc tatcctctga acggctccga cctctctccg gacaagacgc
     2761 ctctggaagc cgggctcggc ttcttctgcg cgctggatac ggatttcatc ggttccgata
     2821 tcctccggga acaaaaagcc aacggtctca gccagcggct ggcggctatt gaatacaccg
     2881 gcaagggagc ccctccccgc gcccattatg ccgttcacgt ccccggcgga gaagccatcg
     2941 gagaacttac cagcggcgtg ctctctcctt cgctgatgaa gggtattgcc ctggcctacc
     3001 tgcctgccgc ccatgccaag gtcggcacgg agctggaaat tgacgtaagg ggaaggaaat
     3061 ttccggccgt ggtcgtaaaa aaaccctttt ataaaaaagg ctgacacgac ggcgcaaaaa
     3121 taaactgaca aacacctcat tttactacac tctcacttca aacaattaca tcttatgcac
     3181 gacgtaccag aaaatctgct gtattccaag gatcacgaat ggattgaaat tgacggggac
     3241 atcggcacca tcggcatttc agaccatgcc caggccgaac tctccgatgt cgtctttgta
     3301 gaccttcccg aagtaggcgc caccgtcgcg gccggcgacc ccgtcgccgt cgtggaatct
     3361 gtcaaagccg ccagcgacgt gtacaccccc gtttcaggag aaatcctgga agtgaatgaa
     3421 gagctttcca atgacccctc cctcattaac tccgacccct acggcgcagg ctggctgtac
     3481 aaaatccgcc tggacgttcc cacggaaacg gaagatatga tgaacgccac ggattacgag
     3541 gaatactgct cctgaaccat tctttcctcc cccgccccgg tgattccatc ccggggcatt
     3601 ttgtttggcc cgtcccgcgg ccggacgcta ttaccagcca gagataccac atgaataccc
     3661 actcagattt tgccagccgg cacatcggcc cccaggggga agaacgccgg gaaatgcttg
     3721 acagcctcgg ctaccggacg cttgacgaac tcattgcgga catcgtcccc gcagatatcc
     3781 gcatgaaggc cccgctggac ctgcccgcag ccaaatcgga aacggaagcc ctggaggaac
     3841 tccgttccat tctgcggaaa aacaagctcc tgaaaacctt cattggccag ggctattacg
     3901 gcaccatcac tccctccgtc atcctccgca atgtactgga gaaccccggc tggtacacgg
     3961 cctacacccc ttatcaaccg gaaatcgccc agggacggct ggaaatgctc atgaatttcc
     4021 agaccatggt ctcttccctg acagggctgc cggtagcgaa cgcctccctg ctggatgaag
     4081 gcaccgcagc agcagaagcc gtcaccatgt gccggaacgc gcgccccaaa gcaaacacct
     4141 tctttgtggc ggacacctgc catccccaga ccatcagcgt catccgtacc cgcgccgcct
     4201 tccagggcgt taacatcatc gtgggagatt gctcatcctt tgaccccgca tccatcggtg
     4261 cggatctggc cggagtgctt gtccaatatc cggacacgct cggccgcatc tgcgactaca
     4321 cggacttctt ttcccgcgtg catgccacgg gcgcgctctg cgtcgtggcg gcggatctca
     4381 tggcccttac cgtcatccgg gaacccggcg ccttcggagc cgatatctgc atcggcaaca
     4441 cgcagcgctt cggcatccca atgggcttcg gcggccccca tgccgcctac atgtcctgca
     4501 cggacgctct caaacgccgc atgcccggcc gccttatcgg catgtccata gataccctgg
     4561 gccgcccggc ctaccgcctg gccctgcaaa cgagggaaca gcatattcgc cgcgacaagg
     4621 cgacctccaa catctgcacc gcccaggtgc tcctggccgt gcttgccgcc ttttacgccg
     4681 tataccacgg acaggaaggc ctcaaacgca tcggcacgga aatccacttg aaaaccaaaa
     4741 gcctgtacaa ggcgctcacg gaagccggca tcgccattaa aaacaaaaac ttctttgaca
     4801 ccctgctgct gtccgttccc ggacaagcgg acgccatggt gcaaaaagcc ctggaagccg
     4861 ggtacaacat ccgcagggtg gatgccgacc acgcagccat ctctctggat gaaaccgcaa
     4921 cctgtgcgga tatagcggca ctggcctccg cccttgcagg tgcggaaaca tccgctgcct
     4981 gcgattgcga cgctcctgcc tgggatcccg tccacacgcg ccagacgcct ttctgcacgg
     5041 aaaaggcttt caactcctac cattccgaaa cggaaatgat gcgctacatc cgccgcctgg
     5101 aatcccggga cctggctcta aatgaagcca tgatccctct gggctcctgc acgatgaagc
     5161 tgaacgccgc ctctgaaatg attcccatca cgtggccgga agccaactcc ctgcatccct
     5221 ttgttccggc ggaccagtcg gaaggcatcc gggaaatgct ctccgtcctg tccgaccgtc
     5281 tggcgaaaat caccggcttt gccgccgtat ccctccagcc caacgccggc gccgcagggg
     5341 aatatgccgg gctactggcc atccgccgct accagaagca cgccggagaa ggccaccgca
     5401 atgtctgcct cattcccacc tccgcccacg gaacaaatcc cgcatcctcc gccatggccg
     5461 gcctcaaggt ggtgcccgtc aaatgcgacg aaagaggcaa catcgacatg gcagacctga
     5521 aatcccaggc ggaagcccat aaggacaatc tctcctgcat catggtcacg tacccctcca
     5581 cgcacggggt atatgaacag acaatcaagg aactctgcga catcgtccat gccaatggcg
     5641 gccaggtgta catggacggc gccaacatga atgcccaggt aggtctgact tgccccggct
     5701 gcattggcgc ggacgtctgc cacctgaacc tgcataaaac ctttgccatg ccgcacggcg
     5761 gcggcggtcc cggcatcggg cccatcggcg tagcggaaca cctcgtaccc ttcctgcccg
     5821 ggcacctcac gctgggccat gaagaagggg ccgtagcgtc tgcggcgtgg ggaagcgcct
     5881 ccatcgccgc catctgctgg atgtacctct ccatgatggg gccggacggc ctcagggaag
     5941 ccacggaaat ggccatcctt aacgccaact acattgccaa gaaactcgga catctcttcc
     6001 cggttctcta ctccggcaac aaggggctgg tggcgcatga atgcattctg gatccgcgcc
     6061 agctcactca tgacgccggc ctcacggtgg atgacattgc caaaaggctc atggactacg
     6121 gcttccacgg ccccaccatg tccttccccg ttccgggcac cctgatggtg gagccgacgg
     6181 aatcggaacc caaaaaagaa ctggaccgct tcattgaagc catggaacgc attcatgcgg
     6241 aaatcacggc cattatcaac ggtacggcag acaaggaaga caacgtcctg aaaaactcgc
     6301 cccataccgc agaaatggtc tccgccgacg aatggcggca cccctactcc cgcagtgaag
     6361 cggcttatcc ggtctccggt ctccttattc acaaattctg gccgtatgta ggccgggtgg
     6421 ataatgtgta cggagaccgc aatctggtct gcacctgcga cacggtggag gaattctcca
     6481 aggccgtaga gttataaaaa tctcatcctt cctttcaaaa aggctgttcc attcatttgg
     6541 agcagccttt ttcttatgtt caagaatcgg atttccaatc cgaaagagca aacatatcca
     6601 gaaaacaatt aagcccaaaa gcaatatggg ttgaaaaaga aaaaaggaac atttctccca
     6661 ccccgctttt cctccccttt cattttgatg acccatttgt tctcaaaata gagtgttgac
     6721 ttcggattgg aaatccgttg agctacgtct cagatgagct ttttctctgc ccttactgtt
     6781 cctggccttc aacagcatct ttctttttcc agggaagatt ccgctatcct caaagggtat
     6841 ggaattctct tcatgatctt tcatcatgtc ttcggcttat acgctctacc cgcaggtgtg
     6901 gatacggcat ggattgctcc ccagcttacc aaagccgctc ccatctttaa aatttgcgtg
     6961 cccattttta ttttcatcac ggggtacgct atgggatgga aaacaaattc atccccaacc
     7021 ttcggttccc tcattaaaac aggcttttcc cattacttta aattctggaa aatttatttc
     7081 ttatgcctcc ttctggctat tctggtttcc tgggcattcc ccttgcccat tttgccatcc
     7141 gttgccgaca tgggttggaa aaatggcctg cttgtcgtaa caggattgag gccctgttat
     7201 cccgactggt ggtacatggc tcttttcgcg gcagccacca tggcccttta tccaatctgt
     7261 gcgtggatca cgcatcacat tgcgcctgtc ccgtccatgg cagctctgct gggagtgtcc
     7321 cttttatttc aaagtacggc ccacattccc agcctgccgg gaatcgccta ttccttccct
     7381 cctttcctgc cctgcttcat tctcggctac atgtgcgcct ttctggcttc acgcctctct
     7441 gctctttcaa tttcccaaag cttgggagca atcctgttgc tggctcttga aatactatcc
     7501 atccatctct tcagtttttc aaaagccaaa accctgacgg ttatctttct cttcaccctc
     7561 tggtgtctgc cttggataac ccggaaactc cgcctcacac cgctcttgac gctgctggga
     7621 acttattccg cacttatgtg gctgaatcac agattcattt tcggctacca cttcagctgg
     7681 gacctctatg gaacccaaag catcagcgta gtattcatcg tgacgctggt ctcctccctt
     7741 ctgctggcca tggccatgca aaaacttttt aaccggatga ttccctcaaa tccgcaaacg
     7801 cagtcaaaaa ctttgtagca actttacaag gtccggattc caacacctct taattccaag
     7861 ggggatctcc gtacttattt tctccaatcc ggctttcccc atgggataaa taccacaaca
     7921 gcagccaccc tatgaaggga acggccagaa aaaccaggaa aaagccgctc ctcccgacat
     7981 catgcagacg ccggaccatg gtagccgcca gcggaataga cagcacggcg agcaccacgt
     8041 acagcagagg ggaaaccagc tcaacccacg gaaccaggga cgggaaaaaa ccgcattccg
     8101 caaaagaggg gactcccgcc acggccagcc acgcaacccc cactctggaa aaaacctcgt
     8161 gcagctcccc tttcccggca cggccctcaa aacggcacca tgccttgatg acgcgtatcc
     8221 agtacttctt cctgctccag ccggagtcgg cgcctccagg ctctgaaccg ggatccggca
     8281 gaacggaggg ctccccatca tcatccataa cagtcatgga ggggataaaa gaggccagag
     8341 gcctccagtc tccgccggga accttccgga ccaaagtccg gttggacagg cggccgaggt
     8401 tacgggcccg cagcaaaagc accaggtcaa ccgggccttt ggaagaaccg tcaattgcct
     8461 gatactcgta cagatcgctc atggggacgc ttacctggat tccttcccgt ggctgaaggc
     8521 ggaggcggga atctccttct tggacaaacc gggaccttcc cacttcaaaa ccagtttgga
     8581 ggcagtaccg gagttcccca catagccaat gcggatggga tgaagtccag ctttcaaata
     8641 aacgggattc ttccggtcac ccagatcgga ggagacctcg gcccccggct cataagtttt
     8701 gtccgcgtca atcaattcca tgccgtgcag acggacaaaa gccttgctgc ccttattttc
     8761 atccgtggtc agataaaacg tatatgctcc gtcctctgga atcttcacat atcccgtcag
     8821 ctccacaccg cgcttgtccg aaccgttcat tttcacggat ggggaaggcg tcacgccatg
     8881 ggcggaagca ggcttcttcc actggcggaa atccggtacc cagggaaaat ccccctcata
     8941 caaggcccat cgcaacccgg gagaaacggt tcccttcaca tccacggcag gcaccagcgc
     9001 agaatcaaac actgttttgg aaggaaggga agcccggcga ttggacaaag cggcggcttt
     9061 catgcgggcc tgaagttccg gcttggagga tgcgagatct ttgctttcct gcggatcatt
     9121 caaagtatca aaaatcatga aatccttgtc cgcatccttc acccccatgc gcaagccttt
     9181 caatccatcc acaaaaacaa tctgctgctg gcctcgctgc gctcccttgt gttcgcccag
     9241 gaaatcctta tactccggcg ttttgccggc gaaattatat tcggcataaa caatgccggg
     9301 cttctgctgg tccgcatgac cggtcagcgt cggcagcagg gaaacgccgt cactgcgggc
     9361 tggaaccggc acctcggcga catccgccag cgtagccagc cagtcatgga actgtccagg
     9421 atgcaggctg atctgccctt tgggaatgcg ggcgggccag cgtaccagcg taggcacgcg
     9481 catgcctcct tcccagcaat cgcgcttaat accgtccatc atgccataac tcttgaaaaa
     9541 ctgcggattt tgcgctccgt gccagtgcct ggagtcggcg ccaccctcat tgtgggggcc
     9601 attgtcggac gagaaaacga tcatcgtatt atcgtcaatc ttcaaatctt tcagcagacg
     9661 gatcaaatca gccacggcat cgtccacgcg gcggatcatg gtggaatgac gtttggccac
     9721 atcattcggg aaacgggaat tgtccggatg aatataggta tccttattct tttccgcctt
     9781 ggcgtcaaaa gccgtattca cggattccgt gccttccttc tttacccatt gcaggcctcc
     9841 tttcaatccg ccgccggaag gatagggaac ccccggaacc accagattgc cgtggggcgc
     9901 cggaaaagcc aggtacagga aaaacggctt tccggtcttg cgggcgaact tgcgctggtc
     9961 cacaatccac tgcttggcgc gggcggcaaa taaatccgtg gaataagccg tctggggcac
    10021 ctggtccttg atatttttcc actcgggatt ggaagcgtaa ccgttgtatt cgaaaacgtc
    10081 acgggattcg gaaggatagt gaaaatgccc tgccaaatgg tccaggatac cgtaaaaata
    10141 attgaatccc cgctgatggg ggccggcggt catgggcaca tggctctggc ctccgccgcc
    10201 tacaccccat ttgccaatgg cggcagtatc atacccggca tcacgcatca cggtacccag
    10261 cgtatgggaa tcttcaatag gctggtcgaa acggttgttt ctcaccacgc gggaattccc
    10321 ctggtgcacc cccagcagca gggaggcgcg cgccggagcg caaaccggag cggcggaata
    10381 atgacggcgc agctgaatcc cctcccgagc cagagcggac agggcaggag tcttgaactc
    10441 gttctttctc tccaccgtcc ggccattcag cttctgctgg ctccagttgg aatccagatc
    10501 accccagccc atgtcgtcca ccagaatgaa aataacattg ggttttgaag ttttgacaga
    10561 ccgggcagcc ggcttcgttg cctgcccgga agcacccatg cacggaacca gggaagtcag
    10621 aagaacggat agtaaagata ccagcttcat gattcaaaga aaatagactc taaaaaagac
    10681 gttaaaataa agcgttatct tacatgaatt ttctcatccc tcaagaaaat tacgaggaaa
    10741 gggcacagag gattgaatcg ccagtattat cggcaaaaaa catcagggaa ccagccttca
    10801 cagccggaac aactacaacc cgccatactg caccaatgag cggcttttct ggctgaagcc
    10861 aggaatggga gaaaattcct cctgcattcc cggcgccccg gtcaccagcc ccgcccggcc
    10921 atgctttatc ctgaataaaa cggcaatccc cccgccgggc agaaaataca gaaaccggcg
    10981 gaaacagcaa tcatgaaccg gaacgttcca aaatgtccgc gccaattccg gaacagcgtt
    11041 aataaccctg tccggaatag cgaaggcatc agaaacgctt cttcctgtcg tccctgcggg
    11101 aacgttcgcc ccagcgttcg ccgcggtcac tgcggaagcc cccgcggttt cccctgaatc
    11161 cgctccggtc actgcggtcc cgctctccgc ggtaactgtt gcggaatcct ccattgcggc
    11221 gggaagagcg cggagttccg gaatattccg gagccccctt gtcttcacgg acattaactt
    11281 catagccgca gacggtagcc gtcgccaggg cctccagaag caggggcgcc acggaagcgt
    11341 ccacttctat cagggaatgc ttggggaaaa tccggatatc gcccacggct cccttttcca
    11401 tttccaccgt attgtaaaat aacccggcta tgtctttggg ccgcaagcca atcatccggc
    11461 ctccattcat aaacagcgta accgtatccc ccttatgctg ccaggaatca cccttctgcg
    11521 ggctctccgc ctcctccccg gtctgcggca tacgccgcgc cctgcgggcg ggcttgtctt
    11581 ccggaatggg ctgcacttcc cggtgcgtac gttcccggag caagtcaaac agggccgcag
    11641 ccatggcctc cggcgcagcc tccacttcct tcaattcctc cggcagcacg gcatccggct
    11701 tgagacgttc caggatatca tccaccaggg actctgtccg gagctggtcc acctgaacgg
    11761 cagtcaacac aggttccgga gtcaacttaa cgccgatgaa acgttcaatg cggctcatca
    11821 gggaaaaatc acggcgcccc acaaaagtga tggccttccc cttgcggccg gcgcgtgccg
    11881 tgcggccgat gcggtgcacg taatcctccg gatcacgcgg caattcaaaa ttcaccacgg
    11941 catccacatc gtccacatcc aggccgcgag cggcaatatc cgtcgccacc agaaggcgca
    12001 ggctcccctt gcggaaggaa tccatcacgc gctccctcat catctggggc atatccccat
    12061 gaaggcgatc caccggataa ccgcgggccg tcagaccgtc caccacgtca tccaccacct
    12121 ttttggtatt ggcgaacacc agccccattt taatctttcc ggtgtcaagc agccggctga
    12181 gtacctcaat ccgggaggaa aacaccactt cgtaataaac ctgttcaatg gtaggcaccg
    12241 tcagcgtagg ccgttcaatg gaaatctgga tgggctcctt catgaacctg ctcaccagac
    12301 ggttgatttc cggagacatg gtagcggaaa aaaacagggt ctgcttcgtt tccggcatgg
    12361 cctccgcaat gcgttcgatg tcttccagaa aacccatatc cagcatctcg tccgcctcat
    12421 ccagaatcag catgcggagt ccgtccagcc ttaatgcccc cgactccatc agatccatga
    12481 cgcgtccggg cgtccccacc acaaactgca ccccgcggcg cagggcgtcc agttgcggac
    12541 ggaaagaagc ccccccgtaa atggggacgg cggaaacgcc gtccataaat aaagcaagct
    12601 tgtccacctc ccggcaaatc tgaacggcca gttcccgagt aggacaaaga gccagcacct
    12661 gaacgcagcg ttcctcaggc tcaatgcact ccagggccgg aatggcgaag gcaagcgttt
    12721 ttccggaacc cgtatgggac agccccacaa tatcggcccc actgatcgcg gcgggaatcg
    12781 cctgctcctg aatggaggaa ggagtatcga agccgagcac ttcgatagcc tccagaatct
    12841 ccggtgaaat accaagagcc gaaaaagaag atgtttgagt catggggaaa aatgatctgt
    12901 caaagtcacg gaagaagctg aacattcttc cctcccgtgt ccagccaaaa gaacggaaga
    12961 taccgtagat gccacgattt ccgcaaagcc gcctgcgaat aaaaaaacgg ctctccccgc
    13021 ttctggtctt tactgtcaca cacggggttg caacttgcag gggcgcattc gcgtatgata
    13081 caaatatttc cctccgaatt catggataaa acgccaaaca aatcacagtc ctccctgctg
    13141 gggattttca tcaacatcct cctcccggtg ttgattctgg actattgcag cgcggggccc
    13201 gccaatcccc tggaacgccc ggaaggagaa aatttctggc atatcggccc ggtatgggcc
    13261 ctcgtcatcg ccctttccct cccccttgtc tatggtatcc gttccctggt cgtctccagg
    13321 aaatttgacc tgatgtccgt cgtaggcatg gccggcgtgc tgctgacggg tgtcatcagc
    13381 atcttcgtca tcggcccgga agggcgcatc cacagcgcca caccctggct gttcgccgga
    13441 aaagaagccc tgatccccct tatcctggcg gcggcggtcg tcgtctcccg gtccgccggc
    13501 acgccccttc tcaacatgtt tatctacacg ccggagttat tcgacgtgcg caggatagaa
    13561 caaacggtgg ccgccaacgg cgaggaacgg gcttatcaga aactgctggc aaactcgtcc
    13621 tggattctgg cgggcacgct ggttgcctcc tccatcggca atttcttcct gagcctctct
    13681 ttcatgtctt ccgtcataca acagccggaa gcggaacagc aagtggccta caacgccgcc
    13741 atcggcagca tcacctggtg gggcttcctg atcatcggaa tccccatcct ggcagccctt
    13801 gtcttcatca tgacccgcct gattaaacgg ctcggcaggc tgaccggcct ctcgcgggac
    13861 gaactccttc tcaaataacc cccaaaccat gcgcctccat acttcatgca tcctggctgc
    13921 cgccatcgcc cttcatgcgg cgtgggcgga cacgccccgg ttcgaccggg tcttcggttc
    13981 ccatatggta cttccccacg ggaaaaacat tcccgtttcc ggtacggccg cccccaacag
    14041 ggaaataacc gtcacttttg gaaacactgc cctgaaaaca aaaaccgact ccaaggggaa
    14101 atggagcgtc acgctgcccc ccatgcctcc ctgcgccaca ggccagacgc tggcggccgt
    14161 gcaaaacggg gactccgcca aattggaaga tgtgctcgtg ggagaagtgt ggctggcttc
    14221 cggccaatcc aacatgctgt tccgcctgaa ccagaccacg acggccaaag aagacatagc
    14281 ggcttccgga gacgaccagc tccgtctgct caacaacgtt ccgcaagccc acaccaacaa
    14341 tgccccctac tccgcgaaag actttgacgc cgtcaccacg gacaacttct ataaagggca
    14401 atgggctgcc agctctcccg ccacctcagg gccaatgact gccgtgggct actacttcgg
    14461 gaaaaaactc cgcgaagggc tgggcattcc ggtaggcatc atccactcct ccctgggagg
    14521 ctcggaaatc gcagcgtgga tcccccggca ggtcattaat gccaacaaca gcttccgcac
    14581 cctgcgcggc aatcactggc tggactcccc ccttatctcc gactgggtga ggggacgggc
    14641 caggaaaaac atctctccgc gtctgaacca gggctctccg gaccatccct acaagccggc
    14701 gttcctttac gaatccggca tcgcatggac aacggccctc cccatcacgg gcgtcatctg
    14761 gtatcagggc gaatccgatg cggagatcat tgacaatgcc caaaacagca tgctgctgaa
    14821 aaccatgatc tcctcctgga gaaaagcttt ccgtaacccg gaaatgcctt tcgtcatgat
    14881 ccagctcccc cgcatcaacg acccgtcaaa aatccgtgcc ggatggccgg aattccgtga
    14941 aatgcaggac gccgtggcca aaaccgttcc aaaagtttac agcgtcaaca ccattgatct
    15001 tggctccacc aattccgacg ttcatcctcc attcaagcgc cctgtggggg aacgtgcagg
    15061 aaatactgcc ctgaacaagg tttacggtaa aaagatcccc tgtgaaggcc ctgccctcaa
    15121 ggccttcaaa ccttccggtt ccaacatcct ggttcaactg gatcaagctg ccggactgac
    15181 caccacggac ggcaaagaac cggcccagtt tgaaattgcc gggacggacg gaacttatca
    15241 tcccgccgca gcggaaatca taaacagaaa aggcaacaca gccgttatcc gcctctcatc
    15301 accggaagta aaatccccca aacacgcccg gtattgctgg aaccgtttcg tgacccccaa
    15361 cctggtcaac ggcaaccagc tccccgcccg tcccttccgg acggacgaac ctgttctgaa
    15421 aaaataactt ttaccacacc atcactccat gaaccttcat cttatcctcg cttctctgac
    15481 agccacactc tcactgggca ttgcggcaca agctgctccc gccaaagtag cctgtgtggg
    15541 ggacagtatc accttcggca ccggccttaa acccggagaa acccggtatc cgcaagtgct
    15601 cgccacactc atggggccgg actttgacgt cagaggcttc ggcaatcccg gaaaaacggc
    15661 aggcgactac ccgggccagg caggacgctg gtacggcagc accagggaac acaagcaagc
    15721 cctggaattc aaggcggata tttatatctg caaccttggc atcaacgaca cgggccgctg
    15781 gtggaacccc gaactgttct ccaaaggcta tgacgctctg cttcatgcgt ggaaaaacgc
    15841 caatcccaaa acacggttct ttgcctgggg gctgctgggg ccggactacc gcggcccgct
    15901 caacaaaaag gcatttcccg gcaactgcta tccggacgta cgtaaatatg caggctcgga
    15961 caacggctca tccgccaacc gcccggaagc ggaaaaactg atcgccgccg tagcgcgcaa
    16021 gtacaaagtc agtctctttg acgcgctgca cccgctctcc gaccatccgg aatggtacgt
    16081 tgacgggttg caccctacgg aacagggcgc acggcgcatt gcggaaatca cctttgccaa
    16141 gctggcaaaa agcctcaggc ttaagcagcc cgcccccaga ttggaaccgg gcaccggcaa
    16201 cgtgattatc aacaacccag gcaactccgg catccttttg gatggatgga aactgacgga
    16261 cggaaccaat acgctcatct ttgaaaactc caccgtcatt catcccaagg acaggcttat
    16321 catcgccatt ggcccggaaa ctcaaaaaga cccgaccaag cccctgcaaa tcaagtcctc
    16381 ccaatccccc gcagctttcc gcctcattcc tgcgaaaaaa tattaaaaac ttccagaacc
    16441 gcttatggga acatgcggaa ctcctgcatg ttcccataag cccggcacac gctattc
//
