LOCUS       c00447_gnlPro..        14226 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JBDCPNAF_447.
ACCESSION   c00447_gnlPro..
VERSION     c00447_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 09:08:28
            Original ID  :: gnl|Prokka|JBDCPNAF_447
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14226
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14226
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1253:4226]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1254..4226
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..14226
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14226
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             105..608
                     /locus_tag="ctg447_1"
                     /transl_table=11
                     /translation="MAMTVTYSVVPRKNPAKKDESAKYYAQAQASGELDFEELCEGITS
                     RSTCTETDVRAAISGILYEAKRALKAGRIVRLGDLGSLQIGLNSEGAVSVKEFSSSLIT
                     AAHIIFRPGKTLADITKILSYQQVTTRAVTQTGGSGNEGEDDDKGSGGGSDGGGSGEAP
                     DPAA"
     CDS             629..796
                     /locus_tag="ctg447_2"
                     /transl_table=11
                     /translation="MKEIVTKILDVIMFLVPFFGKRKRNRIVREVRFNATHKEVCNVKT
                     TEREKDDEKD"
     CDS             783..1226
                     /locus_tag="ctg447_3"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRVDRDFTAKDVDTAHRFRGFSCWGYHYYIRK
                     SGQIEPMRDEDTVGAHARGFNAISLGVCYEGGLDENGKAADTRTSRQKEAMHRLVNELL
                     QRYSEAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVKAETW"
     CDS             complement(1254..1982)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74.2;
                     E-value: 4.3e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg447_4"
                     /sec_met_domain="Radical_SAM (E-value: 4.2e-30, bitscore:
                     94.9, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGVTFSGGEPTFQAKALVPLVRELKEKGIHVCIDSN
                     GGIWNEEVEELFKLTDLVLLDIKEFNPARHQALTGRSNEQTIRTAAWLEENEKPFWLRY
                     VLVPGYSDFEEDIRRLGEALGKYKMVQRVEILPYHTLGVHKYEAMEQEYKLKDVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(1998..4226)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg447_5"
                     /sec_met_domain="Gly_radical (E-value: 4.7e-47, bitscore:
                     148.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1173.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSTEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERANNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLRNLTGPMTDARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYMEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     NFEEVMSNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIQGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATEEDRVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLYDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             complement(4794..5270)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-2S_thioredx"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg447_6"
                     /sec_met_domain="Fe-2S_thioredx (E-value: 2.5e-55,
                     bitscore: 175.9, seeds: 130, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDIKLACDMAEQIKTICDKHGNKPGELINILHEAQHLQGYLPEE
                     TQRIIASKLGIPVSKVYGVVTFYTFFTMTPKGKHPISVCMGTACYVRGSEKLLEEFKRV
                     LGIEVGDTTPDGKFSLDCLRCVGACGLAPVVMIGEKVYGRLQPVDVKKIIEELE"
     CDS             complement(5290..7056)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer2_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NADH-G_4Fe-4S_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg447_7"
                     /sec_met_domain="Fer4 (E-value: 3e-10, bitscore: 29.3,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.8e-05, bitscore: 14.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_4 (E-value: 6.8e-24, bitscore: 73.4,
                     seeds: 126, tool: rule-based-clusters)"
                     /sec_met_domain="NADH-G_4Fe-4S_3 (E-value: 2.2e-19,
                     bitscore: 58.4, seeds: 418, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEKQITLQIDGHFITVPEGSTILEAAIKIGINIPTLCHIDLKGT
                     CIKNNPASCRICVVEVMGRRNLAPACATRCTEGMVVKTSTLRVMNARKVVAELILSDHP
                     NDCLTCPKCGNCELQTLALRFNIREMPFNGGELSPRKREITASIVRNMDKCIFCRRCES
                     VCNDVQTVGALGAIRRGFNTTIAPAFDRMMTESECTYCGQCVAVCPVGALTERDYTNRL
                     LDDLANPDKVVIVQTAPAVRAALGEEFGFPPGTLVTGKMVYALRELGFDYVFDTDFAAD
                     LTIMEEGSEILNRLTRYLNGDKSVRLPILTSCCPAWVNFFEHHFPDMLDIPSTARSPQQ
                     MFGSIAKSYWAEKMGIPREKLVVVSIMPCLAKKYECARDEFKVNGIPDVDYSISTRELA
                     RLIKRANIGFPLVLDSPFDNPMGESTGAGVIFGTTGGVMEAALRSVYEIYTGEPLKNVN
                     FEQVRGLNGVRRATINLNGFELKVGIAHGLGNARHLLEDIRNGHNEYHVIEIMACPGGC
                     IGGGGQPLHHGNSEILYARANALYREDANKPLRKSHENPYIKTLYEDYLGKPLGEKSET
                     LLHTHYFNKAID"
     CDS             complement(7070..8977)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-2S_thioredx"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NADH_4Fe-4S"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg447_8"
                     /sec_met_domain="Fer4_7 (E-value: 1.4e-10, bitscore: 31.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 3.7e-11, bitscore: 32.4,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 9.9e-51, bitscore:
                     161.2, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00027, bitscore: 11.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="Fe-2S_thioredx (E-value: 1.7e-12,
                     bitscore: 37.0, seeds: 130, tool: rule-based-clusters)"
                     /sec_met_domain="NADH_4Fe-4S (E-value: 2.6e-34, bitscore:
                     106.7, seeds: 645, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKILSIHDLATIRKRAKHNLSLREESNEKVTEKCYGLASGAQHLQ
                     ILICGGTGCKASSSQGITDNLLKAIKKNEITDKVEVITVGCFGFCEKGPIVKIIPDNTF
                     YTQVTPEDAEEIINEHIIGGRRIERLLYVDPKTEHTVSDSKHMDFYRKQLRIALRNCGF
                     IDPENIEEYIAREGYFALADCLLNKQPTDVIDIIKRSGLRGRGGGGFPTGLKWEFANKQ
                     QSDVKYVVCNADEGDPGAFMDRSIMEGDPHSIVEAMCVCGYSIGSTKGLVYIRAEYPLA
                     INRLKTAINQAREYGLLGDHILGTDFSFDIEIRYGAGAFVCGEETALIHSMEGKRGEPT
                     LKPPFPAESGYLGKPTNVNNVETLANIPIILTKGADWFATIGTERSKGTKVFALAGKIN
                     NVGLIEVPMGTTLREVIYEIGGGIKGGKKFKAVQTGGPSGGCLTEKHLDTPIDFDNLLS
                     AGSMMGSGGMIVMDEDDCMVSVARFYLDFTVEESCGKCTPCRIGNKRLLELLNKITEGK
                     GTEKDLDTLATLGQVIKDTALCGLGQTSPNPVLSTLDNFYDEYMEHVRDKTCRAKQCKS
                     LLTYTISPERCIGCHLCAKNCPADAISGLVRKPHVIAPDKCIKCGMCMARCKFNAILVC
                     "
     CDS             9141..11894
                     /locus_tag="ctg447_9"
                     /transl_table=11
                     /translation="MRRILLGLCFLSFLNSASGQEIPLPEKMPQTHPRVLTTPAGKQET
                     WKLIKKEEWAKDVFNKLKERTEVYTNLTDAQPAWLLSRLAMYWKSHATEVYVKGETFDH
                     AGGERAPYPTVRYTGTRGTAATHGRPKLADVVPYDDEDGNVTFCNNALPDRPMESVHPS
                     KTGRNIESLNCEILGIARDAAFLYWMTDEEKFAKLAAGVFDTYMTGIYYRNVPIDLNHG
                     HQQTLVGLTSFEVIHEDALHIAVPLYDFLYNYLKANYPDKMEIYAGAFKKWADNIIANG
                     VPHNNWNLLQARFVMNVGLVLEDNKEYADGKGREYYIDYVMNRSSIRQWSLTRLADYGF
                     DINTGIWAECPGYSSVVINDYANFVNQFDTNLQYDLVKAVPVLSKAVATTPQYLFPNRM
                     ICGFGDTHPGYLSTNFFIRMIQNAQANGKKEQENYFTALLKCLNPDLGNDKTEKKNVRV
                     SVNSFFEDKPLTLNPKVQPGKIEDYVSPLFYAPNVSWLVQRNGMHPRNSLMISLNGSEG
                     NHMHANGISMELYGKGYVLGPDAGIGLFLYSGLDYAEYYSQFPSHNTVCVDGISSYPVM
                     KSNHSFDLLSCFPASAEPGKAFTSVTYSNLYFREPESRADQTRMMSIVTTGAETGYYVD
                     VFRSRKEKGGDKMHDYFYHNLGQTLTLTTADGSDLNLQPTEELAFAGAHLYAYSYLYDK
                     KVAATNKDVKATFTIDMKDKDGDDIYMNLWMKGEPDREVFTALAPMTEGLSRTPNMPYN
                     IKEQPTLTFVARQHGEAWNRPFVSIYEPSTKKEPSAIQSVSYFDAEGAGLEDFAGICVK
                     SKNGRIDHIFSLSDAAQTATYQGMKVKADYAVISNEYAGNRTLFLGNGTQLVAPGVMIQ
                     TDNAANVLLEKKEGKWYIISSAPCTVVIGDKKIKSDAASEPMLLRI"
     CDS             12123..12680
                     /locus_tag="ctg447_10"
                     /transl_table=11
                     /translation="MVYVMRNGRRVIAALSFLLLCCGVHVHAQRVAVKTNALGWLTASP
                     NVEAEFVLGSHVSLNMGIAANPISTDNFKTTFTHFQPEVRYWLNRPMVSHFLGITAFVN
                     NFDMMVKDVHHKGDAYAAGLTYGYAWVLGDHWNIEATAGVGVLRYRQFKYDKGTPKPGA
                     VNDSKTTIAPVKLGVSFVYIIR"
ORIGIN
        1 gaaacttcgt tggggaatcc ggaggatgga aaatgtgtta tctttatgtc gttaacaaat
       61 aaggaacgcg ttcgaaatgt gtgaaatctt aaaattattt tattatggca atgacagtaa
      121 cttattcagt agtgccgcgc aagaatcctg ccaaaaagga tgagtcggca aagtattacg
      181 cgcaggcaca ggcttcggga gagttggatt ttgaagagtt gtgcgaagga atcaccagtc
      241 ggtctacctg tacggagaca gatgtgcgtg ccgccatttc gggtattctt tatgaggcga
      301 agcgtgcgtt gaaagcggga agaatagtcc ggttgggtga tttgggcagt ttgcagatcg
      361 ggttgaacag tgaaggagct gtgtcggtca aggagttttc aagttcgctg attacggctg
      421 cccatattat tttccgtccc ggaaagacgt tggcggacat cacgaagatt cttagctacc
      481 aacaagtaac gacgcgtgcg gtgacccaaa cgggcggtag cggcaatgaa ggagaagacg
      541 atgacaaagg ttccggtggt ggttcagacg gtggtggaag cggagaagct ccggatccgg
      601 cagcatgata actttaatat tagatcaaat gaaagaaatt gtaactaaga ttttggatgt
      661 aatcatgttc cttgtgcctt tcttcggaaa aagaaagcgg aacagaattg tgagagaggt
      721 gcgcttcaat gctacccata aggaagtgtg taatgtgaaa acgacggaaa gggagaagga
      781 cgatgagaaa gattagtctg attgtgattc actgctctgc tacccgtgtc gatcgcgact
      841 tcacggcgaa ggatgtggac actgcccatc gctttcgggg cttttcgtgt tgggggtatc
      901 attattatat ccgcaagtcg ggacagatag aaccgatgag ggatgaagat acggtgggtg
      961 ctcatgcacg cggttttaat gcgattagtt taggggtgtg ctatgaaggc gggctggatg
     1021 agaacggaaa ggcagcagat acgcgtactt cccgccagaa agaggcgatg catcgcctgg
     1081 taaacgagtt gttgcagcgt tattcggagg caaaggtggt cggtcatcgg gacttgagtc
     1141 ctgacaccaa ttataatgga attgttgacc cttgggagcg gatcaaagag tgtccctgtt
     1201 tcgaggtgaa agcagagaca tggtgatttt tatcctattt attactgtgg tggttaattg
     1261 accaccacag tagtgaaata ctctttaaat acctccgcag ctttttcaag ttgttcgggg
     1321 gtattttctt ttacgtcttt cagcttgtat tcctgctcca tcgcttcata cttatgtacg
     1381 cctaatgtat gataaggcag gatttccact cgttgcacca tcttatattt tcccagagct
     1441 tctcctaaac ggcggatgtc ttcctcgaaa tcgctgtatc cgggcactaa tacataacgc
     1501 agccagaaag gtttctcgtt ttcttccagc catgctgccg tgcggatggt ttgctcgtta
     1561 cttcttccgg tcagtgcttg atggcgtgcc ggattgaact ctttaatatc cagcaataca
     1621 agatccgtca gtttgaaaag ttcttcaact tcttcgttcc agataccgcc gttgctgtct
     1681 atgcatacat gtattccctt ttctttcagt tcacgcacta aagggactag tgctttggcc
     1741 tgaaacgtag gttctcctcc ggagaaagtg actcctccgc gtttcccgaa aaaaggacgt
     1801 tggctcatag ccatgcggac gatttcttcc ggtggggtag gtgtgcctcc ttttccggct
     1861 atcgtgtcgg ggttggcaca atacaggcag cggaaattgc atccttgaag aaaaacgacg
     1921 agccgtaagc ccggcccgtc gaatgttccc atactttcgt atgaatgtac gtttatcgtc
     1981 atattgagta gatctgatta catacgttcg tggaagctac ggctgattac ttccaattga
     2041 tgttcgcggc tcaacttcac gaagtttacg gcataaccgg aaacacggat ggtgagttgc
     2101 ggatattttt ccggatgttc catggcatcg taaagcattt cacggttcag tacgttcacg
     2161 ttcaggtggt gagcgccttt ggtgaaatag ccatccatca ttgtcaccag attttctacg
     2221 cgatcctctt cagtagctcc cagtgatttg gggacgatgg agaaagtgtt gctgataccg
     2281 tcctgtgagt cgcggtaacg taatttcgct acggaactca aagaggcgat ggcaccgttc
     2341 ttgtcacgtc cgtgcatagg gttggctccc ggagcaaaag cgacaccttt ggcgcgtccg
     2401 tcgggagtag cacctgtctt cttgccatac atcacgttgg aagtgatggt gagcaaagat
     2461 aaagtaggac gggcattttt gtaaaccgga agtttcttca attcttcgct gaagaaatag
     2521 accaggtcaa cacccaggtg gtctaccttg tcgttgtcat taccgaagca agggaattcg
     2581 ccttgaatat cgaaaccttc tgtcagaccg atgtcattgc ggcgtgcggt cactttggca
     2641 tatttgatgg ccgacagtga atcgagggcg atagaaagtc cggctacacc ataagcaagg
     2701 ttgatgcgtg ggttggtatc tacaagagcc atttgggctt tttcgtagta atacttatca
     2761 tgcatataat ggatgatgtt catcgcttcg ttgtaaacac gggcgatttc cgtcaatacc
     2821 ttcttgtagt tgctcattac ttcttcgaag ttcagtgtgt cgctggttag tacggggata
     2881 tttttcacca ttaccgtacc ggtgttttcg caacgtccac cgttgatggc aagcaacagg
     2941 gcttttgcca ggttgcaacg tgcgccgaag aattggattt gttttccgat ttcctgataa
     3001 gatacgcagc atgcgattcc gtaatcgtca gactggcgca cttcacgcat caggtcgtcg
     3061 ttttcatatt ggatggaaga agtgtcgata gatacttttg cgcagaattc tttgaatcct
     3121 tccggcagtt ccgggctcca caatacagtc aggttcggtt ccggtgaagg gccgaggttg
     3181 tagagtgttt gcaggaagcg gaaagaagtc tttgtcacct tcgtgcgtcc gtcgttgagg
     3241 cgtccaccca gggattcggt tacccatgtc gggtcgccgg caaagatgtc gttgtaagat
     3301 tgcatacgca ggtgacgcac catacgcagt ttgatgacaa actggtcgat cagctcctgt
     3361 gcgaaagatt ctgtgatggt tcctttgctc aattcatatt ccatataaat gtcgaggaac
     3421 gaagagacgt tacctagtga catagcagca ccgtcttgtt cttttacggc agcgaggtaa
     3481 gccatgtata cccattgtac tgcttcttgt gcggtgtagg caggacggct caagtcgagt
     3541 ccgtagtatt cgcccattac cttcatgtcc ttcaatgcct tgatttgctc tgccacttct
     3601 tcgcgcaggc ggatgcgggc atcggtcatc ggaccggtaa ggttacgcaa gtcttctttt
     3661 tttgcctcaa tcagtcggtc gataccatag agagccatac ggcggtagtc gccgatgata
     3721 cgtccgcggg catagttgtc aggaagtccg gtgaggaatc ccagagaacg gaacgaacgg
     3781 atttcttcgg tatatacgtc aaatactccg tcattgtgtg tcttgcggta gtgagtgaat
     3841 atatctttta cacggtcgtc cacttccacg ccgttttcgt ggcaggcttt gctcaccacg
     3901 ttgatacctc cgaaaggttt gattgcacgt ttcagaagtt cgtctgtttg cagaccgacg
     3961 atcagttcgt tttctttgtc gatatatccg gctttatgag aagtgatggt tgagacggtg
     4021 acattatcca gtgagcgtac tccgttattg gctctttctt ctgccagtgc ttcgaggcag
     4081 cggttccata cagctttagt gcgttcggta ggtccttcga ggaaagaagc atctccataa
     4141 tacggagtga tgttgtggct aacgaaatct cttacgttga tttctgtgct ccaaagaccg
     4201 tctttaaaga tcttatttaa ttccataaat gataaaatta gaggttgtag ttatcctttt
     4261 ctttagagcg cacaaagtta caacgttttt tcatataatc agcataaata tgctctattt
     4321 tatgcttttc aacataaaat acctagatat tgctattctt tggaaatgat gttcgtgatt
     4381 ttttttgtga aaactcttgc aagtttaaaa tatcttcgta cctttgcacc gcttttaacg
     4441 aaaagcactt ctgataaaga agttttggag aggtggcaga gtggtcgatt gcggcggtct
     4501 tgaaaaccgt tgtactgcga ggtacccggg gttcgaatcc ctgtctctcc gctagaaagc
     4561 agctttttgc tgctttctgt ttttatggag agttttttct ctagttggta attgtaagga
     4621 gaggtgctcg agtggttgaa gaggcacgcc tggaaagcgt gtatacccct aaagggtatc
     4681 acgagttcga atctcgttct ctccgcatca tttttttaca ttttaatatt aatgaacggc
     4741 tgttttgact tatcaaggca gccgtttgtt ttatattgtt ttcgggaatt cggttattcc
     4801 aattcttcaa taatcttctt tacatctacc ggttgtaatc gaccatatac cttctcgccg
     4861 atcatcacta ccggagccag tccgcaggcg cctacacaac gcagacagtc taatgagaac
     4921 tttccgtccg gggtagtgtc accgacttcg atacctaata cacgtttgaa ctcttccagt
     4981 agtttttctg aaccacgtac ataacaagct gtacccatgc aaacagagat gggatgtttt
     5041 cctttgggag tcatggtaaa gaaagtatag aaagtgacga caccatacac tttcgatacg
     5101 ggaattccaa gtttggaagc gataatccgt tgcgtttcct cgggtagata cccttgcaaa
     5161 tgctgtgcct catgcaaaat attgataagt tcgcccggtt tgtttccatg cttgtcgcag
     5221 atcgttttga tttgctctgc catgtcacag gctagtttga tatctgacat aatactcttc
     5281 atttaaaagt taatcaatcg ctttgttgaa ataatgcgta tgcaggagag tttccgattt
     5341 ctcacctagc ggtttgccga gataatcctc gtataatgtc ttgatatacg gattctcgtg
     5401 cgatttgcgc aaaggtttgt tggcgtcttc acggtaaagt gcgttggcgc gtgcatagag
     5461 tatttccgag ttgccgtgat gcaaaggctg cccgccgcca ccgatacagc ctccggggca
     5521 agccataatt tcgattacat gatattcgtt gtgcccgttc cgtatatctt ccagtagatg
     5581 acgagcgttg cctagtccgt gtgcaatgcc tacttttaat tcaaatccgt ttaggttaat
     5641 ggtagcacga cggacgccat ttagtccgcg tacctgttcg aaatttacat ttttcaaagg
     5701 ttctccggta tagatttcat agacagaacg gagggcggct tccattacac cacctgttgt
     5761 tccgaaaatg acaccggcac ctgtcgattc acccatcggg ttgtcgaatg ggctgtccag
     5821 tacgagaggg aacccgatat tggcacgttt aattagtcgt gccagttcac gggtagagat
     5881 agaataatcc acatcgggga taccgttcac tttgaattca tcacgtgcac attcgtactt
     5941 tttagccaga caaggcatga tagatacgac aaccagtttt tctctgggta tgcccatttt
     6001 ctccgcccaa taggatttgg caatggaacc gaacatctgt tgtggggagc gggcggtgga
     6061 cggaatgtcc agcatgtccg ggaaatgatg ttcgaagaag ttgacccatg ccggacagca
     6121 ggaagtcagg ataggtaatc gtacggattt atctccgttg agataacgtg tcaggcggtt
     6181 cagaatttca gaaccctctt ccataatggt aaggtcggct gcaaaatcag tatcgaatac
     6241 atagtcgaat cccagttcgc gaagtgcata caccattttt ccggttacca gagtgccggg
     6301 aggaaatccg aattcttcac ctagggccgc ccgtacggca ggtgcggtct gcacaatcac
     6361 tactttgtcc ggattagcca gatcgtcgag cagacggttg gtgtagtcac gttctgttaa
     6421 tgcgcctacg ggacagacag ccacgcactg accgcagtaa gtacattcac tttccgtcat
     6481 cattcggtca aaggcaggag cgatggttgt attgaatccg cgacggatgg cacccaatgc
     6541 tccgaccgtc tgtacatcat tgcaaacact ttcacaacgg cgacagaaaa tgcatttatc
     6601 catattacgg acgatagaag cggtaatttc ccgtttgcgg ggggacagct caccgccatt
     6661 gaaaggcatt tcgcgaatgt tgaaacgcag tgctaacgtt tggagctcgc agttgccgca
     6721 tttagggcaa gtgaggcagt cattggggtg atccgaaagg atcagttcag ccaccacttt
     6781 gcgagcgttc attacgcgca gggtactggt ttttactacc atgccctccg tgcaacgggt
     6841 agcgcaggca ggagccaggt tgcgccgtcc catcacttca accacacaaa tacggcagga
     6901 agccggatta ttttttatac aggttccttt caggtcgata tgacacagcg taggtatatt
     6961 gataccgatt ttgatagcgg cttcaagaat agtgcttccc tcgggcacag tgatgaaatg
     7021 accgtctatc tggagagtaa tttgtttttc ttccatagta aataagattt tagcagacaa
     7081 gaatagcgtt gaatttgcag cgtgccatgc acatgccgca tttgatacat ttatcgggag
     7141 caatgacatg tggcttgcgc accagtccgc tgatagcatc cgccggacag tttttagcgc
     7201 atagatgaca accaatgcag cgttccggac tgatggtata tgttaatagt gatttacatt
     7261 gcttggcgcg acaagtctta tcccgcacgt gttccatata ttcatcgtag aagttatcca
     7321 atgtggataa aacgggattt ggagaggttt gtcccaatcc gcagagggca gtatctttga
     7381 tgacttgtcc caaagtggca agtgtgtcca ggtctttttc tgtgcctttt ccttccgtaa
     7441 tcttgttcag tagttccagc agacgtttgt ttccaatgcg gcaaggtgtg catttcccgc
     7501 aggactcttc cactgtaaaa tccagataaa agcgggctac ggataccatg cagtcgtcct
     7561 catccatgac aatcatccct cctgaaccca tcatggaacc ggccgagaga aggttgtcaa
     7621 agtcaatggg agtgtccaga tgtttttctg tcagacagcc gcctgacggt cctcctgttt
     7681 gtacagcttt gaacttcttt ccgcctttga tgcctcctcc gatttcgtag attacttccc
     7741 gaagagtagt tcccatcggc acttcgatca gtccgacatt attaatcttt ccggcaagag
     7801 caaacacttt ggttcctttg gaacgttctg tgccaatcgt tgcaaaccag tcggctcctt
     7861 tggttagaat aatgggaata ttggcaagcg tttccacatt atttacattg gttggttttc
     7921 ccagataacc ggattcggca gggaagggag gtttcagagt cggctctccc cgttttcctt
     7981 ccatcgaatg aataagggca gtttcttctc cgcagacaaa agctccggct ccgtatcgta
     8041 tttctatgtc gaaactgaaa tctgttccta agatatgatc tcctagtaat ccgtattcgc
     8101 gtgcctgatt gatagctgtt ttcagtcggt tgatagctaa cggatattcg gcacggatat
     8161 atactaatcc tttggtggaa ccaatggaat aaccgcagac acacatcgct tctacaatcg
     8221 aatgtgggtc gccctccata atggaacggt ccatgaatgc accgggatct ccttcgtcgg
     8281 cgttacaaac cacgtatttg acatctgact gttgcttgtt ggcaaattcc catttcagtc
     8341 ccgtcgggaa accgccacca ccacgtccgc gaagtcccga acgtttgata atatcaataa
     8401 cgtccgtcgg ctgtttgtta agcaggcaat cggccaatgc aaagtatcct tcacgggcga
     8461 tatactcttc aatattttcg ggatcgataa aaccacagtt acgcaatgcg atgcgaagtt
     8521 gtttccggta gaaatccatg tgcttggagt cgctgacggt atgttccgtt ttaggatcta
     8581 catacagcaa ccgttcgatt cttcgtcctc cgatgatatg ctcgttgatg atttcttccg
     8641 catcttcggg agtgacttgg gtgtaaaagg tattatcggg gatgattttc acgataggac
     8701 ctttttcaca gaagccgaaa cagcctacgg tgatgacttc tactttatcg gtgatttcgt
     8761 tctttttgat ggcttttaga agattgtctg taataccctg gctggaagat gccttacagc
     8821 ctgtaccacc gcagatcaga atctgaagat gttgcgcacc ggatgccagt ccgtaacact
     8881 tttcagtcac cttttcattg ctttcttcgc gcaatgaaag attgtgcttt gctctcttcc
     8941 tgattgttgc caaatcatgg atagataaaa ttttcataag tatcagaatt gttagtcggt
     9001 tttttgcaaa tataattctt tgtttgaaat aacagcgtag tctcgtacaa ataaaattgt
     9061 tctttgacgg aggatttagg taaataaatc tctatcttcg tatttaatag gtatcaaacc
     9121 taaaaaaaga aaattgaagt atgagacgaa ttttacttgg actatgtttt ctatcctttc
     9181 tgaacagcgc atccggacaa gagattcctt tgccggaaaa gatgccgcag acacatccgc
     9241 gggtactgac tactccggcg ggaaagcagg aaacatggaa gctgattaaa aaagaagaat
     9301 gggcgaaaga tgttttcaat aaattgaagg aacggacgga agtatatacg aacctgacgg
     9361 atgctcaacc ggcgtggttg ctgtctcgtt tggcaatgta ctggaagtct catgccacgg
     9421 aagtatatgt gaaaggtgaa acgttcgacc atgcaggtgg tgaaagagct ccttatccca
     9481 ctgtgcgcta cacgggaacc cgtggcacag ctgctaccca cggccgtccc aaattggcgg
     9541 atgtcgttcc ttatgatgat gaggatggga atgtcacttt ctgcaataat gcacttcccg
     9601 accgtcctat ggagagtgta cacccatcca aaacaggccg gaatattgaa agcctgaact
     9661 gcgaaatcct gggaattgcc cgtgatgccg ctttccttta ttggatgacg gatgaagaga
     9721 aattcgctaa acttgccgca ggggtctttg atacatatat gacgggtatt tattatagaa
     9781 acgtgcccat cgacctgaat cacggccatc agcaaacatt ggtaggattg acttctttcg
     9841 aagtcatcca tgaagacgca ctccatatcg ctgtaccttt atacgatttt ctatataatt
     9901 atctaaaggc caattacccg gataaaatgg aaatctacgc cggggctttt aagaaatggg
     9961 cggataatat cattgcgaac ggtgtacctc ataacaactg gaatttgcta caggcacggt
    10021 ttgttatgaa tgtcggattg gtattggaag acaataaaga atatgccgac ggaaaaggac
    10081 gtgaatatta tatcgactat gtgatgaacc gttccagcat ccgccagtgg agtctgacgc
    10141 gattggcgga ttatggtttc gatataaata cgggaatttg ggcagaatgt ccgggatata
    10201 gcagtgtggt aatcaatgat tatgccaatt tcgtgaatca gtttgatacg aatctgcaat
    10261 atgatttggt gaaagcagtg cctgtattgt cgaaagcggt agcaaccact ccccaatatc
    10321 tgtttcccaa ccgtatgatt tgtggctttg gagatacgca tccgggatat ttgagtacga
    10381 acttctttat ccgtatgata cagaatgcac aggcgaacgg gaagaaagaa caggaaaact
    10441 atttcacggc tttattgaaa tgcctgaacc cggatttggg aaatgataaa acagaaaaga
    10501 agaatgtgcg tgtatctgtc aattctttct ttgaagataa accgctgacg ctaaatccca
    10561 aagtgcagcc gggaaagata gaagattatg tttctccttt gttttatgct cccaatgtgt
    10621 catggctggt acagcgtaac ggtatgcatc cgcgcaacag tttgatgatt tcgttgaatg
    10681 gcagtgaagg gaatcacatg cacgctaacg gcatttcgat ggaactttac ggaaaaggat
    10741 acgtattggg tccggatgca ggtatcgggc ttttcctgta tagcggactg gattatgcgg
    10801 aatattattc tcaattcccc agtcataata cagtttgtgt ggatggaata tcgagctatc
    10861 cggtgatgaa aagtaaccat tcttttgatt tgctttcctg tttcccggca tcagcggaac
    10921 cgggcaaagc atttacgtcc gttacttaca gtaaccttta ttttcgtgaa ccggaaagca
    10981 gggcggatca gacccgtatg atgagtattg tcactactgg ggcggagacg gggtattatg
    11041 tcgatgtatt ccgcagccgg aaagagaaag gaggcgataa gatgcacgat tatttttatc
    11101 acaaccttgg gcagactttg acattgacga cagcagatgg cagcgacctg aatctccagc
    11161 ctacggaaga actcgccttt gcaggcgcac atctttacgc ttattcctat ttatatgata
    11221 agaaagtggc tgcgaccaat aaggatgtca aggcaacttt caccatagat atgaaagata
    11281 aggacggcga tgatatatac atgaatcttt ggatgaaagg cgaaccggat cgtgaagtct
    11341 ttacggcttt ggcgccaatg accgaagggc taagccgtac accgaatatg ccctataata
    11401 taaaggagca gccgacgctg acatttgttg cccgtcagca tggagaagct tggaatcgtc
    11461 cttttgtctc gatatatgaa ccgagtacga aaaaggaacc gtctgctatt cagtctgttt
    11521 cttattttga tgcagaagga gcaggtttgg aagactttgc cggtatctgt gtgaaaagca
    11581 aaaacggacg tatagatcat atcttctctc tatctgatgc tgcacaaacc gctacttatc
    11641 aaggaatgaa agtgaaagcg gattatgctg ttatcagcaa tgaatatgca ggaaaccgga
    11701 cgttgttttt agggaatgga acccaattgg ttgcacccgg ggtaatgatt cagaccgaca
    11761 atgccgctaa tgtattgctc gaaaagaaag aagggaaatg gtatattatt tcttctgctc
    11821 cctgtacggt tgttatcggc gataagaaga taaaatccga tgctgcgtcg gagcctatgt
    11881 tgttgcgtat ctgatgtttc attggtaata aagaaaaatt gtatatctta tccgtagtat
    11941 ggtatattat ggcctaagat ggaaattgtt gcaataaaaa acaaaaaaag cgtgtttaaa
    12001 cgtttttaat actatatttt ttctaatttt gtggctttct gtccaagtag tatataaaat
    12061 ggacagtaag cccttttttg tgggtaaata tttagtggga aatatttagt gggaaataaa
    12121 tgatggtata tgtgatgaga aatggtcgca gggtaatagc tgcgttatca tttctgttat
    12181 tatgttgtgg tgtacatgtg cacgcacaac gggtggctgt aaagacaaat gcattgggtt
    12241 ggctgaccgc cagtccgaat gtagaagcag aatttgtatt gggtagtcat gtctccttga
    12301 acatggggat tgctgcgaac ccaatcagta cagacaactt taaaacgact ttcacgcatt
    12361 ttcagcctga agttcgttac tggctaaatc gtccgatggt gagtcatttt cttggaatca
    12421 ccgctttcgt gaataatttt gatatgatgg taaaagatgt gcatcacaaa ggcgatgcat
    12481 acgccgccgg tttgacctat ggatacgcat gggtgctggg cgatcattgg aacatcgaag
    12541 caactgccgg agtgggtgtg ttgcgctacc gtcagtttaa gtatgataag ggtactccga
    12601 aaccgggtgc ggtcaacgat agtaagacca ccattgcacc tgtcaaactg ggggtatcct
    12661 ttgtttatat tattcgataa cgaacattag ctagtcagaa aagagaatga aaatcaattt
    12721 gaaacgtgat agattaacag gtatacttct cgtggcgatg atgttcgtcg gtatgaatgt
    12781 atccgcccaa cggatccgcg tgcaggggca tatcacaaac ccgcagggaa aaagtgttcc
    12841 gaatgtaaat gtgttgaatc cggtcaatga cgaacgtata gaaatgtccg acgaggatgg
    12901 tcgttacagt gtcttggttg agaaaaacgg ctcgttgaag tttacatgtg tcggttatga
    12961 agacaaaaca gtgaaggtgg caggaaagca gattctgaat gtagtattga aagatgccgt
    13021 catcgaactg gacgaagtta cgattacttc caaagtgaag gacaaagtga ttccggaacc
    13081 tacggacatc gaaatcaaag gtaattattt tcatctgaaa acccgtgtcc cggtgcctaa
    13141 ggagatgttt aactcacatc gtcgcttggt attgcagcct tccatttatg atgtgacact
    13201 gaaaaagcgt ctgttgatgc gtcctgttgt attcgacggg gatacttata atacaacgca
    13261 aaatcgaatg tacgattatg atatggataa agatcctttg cacgattaca tccgtgtgaa
    13321 aactacttct tcacgcaagg gggatattat tgcttaccat gattctatct atatagaata
    13381 tctgcaacat gactaccgtg cagatgtgca tctggcgatg gaaaattacc ggaatatcat
    13441 ttatcgtgac tctttctcca ttgcacgcgg aacggtcaac ccgcttcgtt tcttggagta
    13501 taaattctcc gctttcagcc tgacggacga gaaatatctt ccgaaacccg tgatgcagtt
    13561 gcgggatacg aaaggtgagg taaacttaac cttcctggta ggtaaagccg acctggatga
    13621 taagaatcca caaaatcagg tggaactgaa ccgattgaat caggaattac gtgctattga
    13681 gacgaacccg gatgcctctt tgaagagttt tcatattacg ggggtggctt cgccggacgg
    13741 ttcttacgcg acgaatcttc gtctggcaaa attgcgtacg gataaggccc tggaacgtat
    13801 actggcacaa ctggacccgg aaacacgtaa actgttggag gtgaaatcgg atgcatcggt
    13861 tgcctcctgg aaggaggtag ctgaattgct gaaaaaaaac tccaagccgg aactggctaa
    13921 agaagtagag gacttaatca aacaatatgc agctactcct taccggttga atggggtctt
    13981 gaaatcgaaa cctttctaca aggaacttgc ggctacttat ctgcctaaat tgagaaaggt
    14041 gcaatatacc tatggttatt caatcttccg ttctttgacg gacgacgaga ttagagaact
    14101 ttacagaaag aatccgaagc aactgacccg tttcgaatat taccgtatga ttacgacagc
    14161 aaaaactccc gacgaaaggg aaaagtattg cagggaagct cttgaacttt atgataactt
    14221 tacgta
//
