LOCUS       c00095_gnlPro..        13176 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OANONJOL_95.
ACCESSION   c00095_gnlPro..
VERSION     c00095_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 10:16:14
            Original ID  :: gnl|Prokka|OANONJOL_95
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13176
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13176
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[217:3176]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      218..3176
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13176
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13176
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             3..89
                     /locus_tag="ctg95_1"
                     /transl_table=11
                     /translation="QRYESFFNLQIIPQKNIRKVYLEVITAI"
     CDS             218..2446
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg95_2"
                     /sec_met_domain="Gly_radical (E-value: 1.5e-46, bitscore:
                     148.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1164.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFKDGLWSKEINVRDFVSNNITPYEGDASFLQGPTERTKA
                     VWNHCLKALEEERNNNGIRALDYTTVSTITSHPAGYIDKENELIVGLQTDQVLKRAIKP
                     FGGINVVMKACRENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGLDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKEIK
                     VLGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSQ
                     GTITETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKAFCAQVSIDTSSVQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKDIPVLTGETL
                     KFEEVMANYKKVLIQIARVYNEAMNIIHYMHDKYYYEKAQMAFVETDPRINLAYGVAGL
                     SIAIDSLSAIKYAHVKARRNDIGLTEGFDIEGAFPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGIAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATQEDRIDNLVTMMDGYFTKGAHHLNVNVLN
                     REMLQDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             2451..3176
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.3;
                     E-value: 1.6e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg95_3"
                     /sec_met_domain="Radical_SAM (E-value: 2e-30, bitscore:
                     97.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAKGG
                     TATDPEEIVRMAVSQKAFFGKKGGITFSGGEPTFQAKSLIPLFKRLKEAGIHICLDTNG
                     GLWNNDVEELLELTDLVLLDIKEFNPEHHQSLTGRSNEQTLKTAAWLETNHKPFWLRYV
                     LVPGYSDFEDDIRQLGEHLGTYQMIQRVEILPYHTLGVHKYEAMNKEYMLKGVKENTPE
                     QIEKAEKLFRQYFRTVQVN"
     CDS             complement(3409..4668)
                     /locus_tag="ctg95_4"
                     /transl_table=11
                     /translation="MKEDEKWIKAFKDKLEDYSEPMPASGWERLERELMPVTEKRIYPY
                     RRWAVAAAAVVLVVTTAVSLYFLNSPVADEIRYATAPSLAVNPDVLPEPALPDVQVAVS
                     EPVKPVGTTSINPVSGYLAKNTDPVIVPEVSSLAEKQPEAVTEEKRAEPQQEATAAIEK
                     KESVTAQPPKRKEARRPSGKDKYQLPIGDSSAKRGGKWSMGVGIGNGGGLPTNGSENFA
                     PRPMTNRVDLMTIMNGAVSIPADQEVIFEEGVPYLKSNTTAVVDYEHHQPVSFGLSVRK
                     SLPKGFSVETGLTYTLLSSDIKRQGDTKMQSQKLHYIGIPVRGNWNFLEKKYFTLYVSA
                     GGMVEKCVYGKLADDKVNVKPLQFSVAGVVGAQFNATDHVGLYVEPGVSYFFDDGSKVQ
                     TIRKERPCNFNLQAGLRFTY"
     CDS             complement(4723..5271)
                     /locus_tag="ctg95_5"
                     /transl_table=11
                     /translation="MNELELSERCRQGDNRARKELYEQYAGRMLGVCLRYAGDRDMAQD
                     LVHDGFLKIFDSFDKFTWRGEGSLRAWMERVMVNTALQFLRKNDVMNQTTALDEVPETY
                     EEPDASAVEAIPQKVLMQFINELPAGYRTVFNLYTFEDKSHKEIAQMLGINEKSSASQL
                     FRAKSVLAKKVKEWLVTNG"
     CDS             5459..6211
                     /locus_tag="ctg95_6"
                     /transl_table=11
                     /translation="MKKFNLITFAVILMLLPILQSCLDDANNDEWVTCPPGGILAIGTM
                     KIPNADTPRDFFIALDNGDNVLPADTADIRNRKYTVAEGQRVFVGYLQMGEEKPGYENG
                     KIFTIEDILTKEIIPLTEATADSIGDDRINVTAHALTKDYLTIEYQYLGSMNENKKHML
                     NLVQNEITGPIKDDGYIYLEFRHNAFNDSPNQLGSSLVSFKLDSIAEQLATAKGIKLRV
                     NTIYDNIQYVTIDINEDKNLKIKSFHSQ"
     CDS             complement(6316..7314)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -3.5; E-value: 38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg95_7"
                     /sec_met_domain="LysR_substrate (E-value: 7.3e-47,
                     bitscore: 150.8, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 3.1e-18, bitscore: 57.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVKLKISIFALIDSISLINQRTMTIQQLEYILAVDQFRHFAKA
                     AEYCRVTQPTLSAMIQKLEDELGVKLFDRSMTPVCPTAIGKKVLEQARKILSEVICVKE
                     IISEEQHSLSGTFRLAVLPTIAPYLLPRFFPQLMEKYPDLDIRVMEMKTPDIRKALLTG
                     EADAAIIASMLDDAALTEETLFYEQFLGYVSKKEPLFKHDVIRTSDVTGERLWLLDEGH
                     CFRDQLVRFCQMEAVKISQMAYRLGSMETFMHMVESGKGITFIPELAVMQLSEEQKELV
                     RPFAIPRPTRQIVLVTRKDFIRTSLLQVLKEEIQAAVPKEMLTLQAVQCLV"
     CDS             7384..7857
                     /locus_tag="ctg95_8"
                     /transl_table=11
                     /translation="MKTLNYTHLEEKGANTIVLSLQQLLADFQIHYANLRGFHWNIKGH
                     GFFVLHSKFEDLYNGAAEKVDEIAERILMLGGTPANKYSDYLKMAQIKEVDGVNKADDA
                     LNHILETYGHLIAEERKILSLASSHNDEVTVAMMSDYLKEQEKMVWMLTAYNG"
     CDS             complement(7961..8959)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_130"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg95_9"
                     /sec_met_domain="Glyco_hydro_130 (E-value: 1.6e-69,
                     bitscore: 225.7, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIKIAGAALPAMPWEERPAGCKDVVWRCSVNPIIPRDLLPTSN
                     SIFNSAVVPFKDGYAGVFRCDDTNRRMRLHVGFSKDAVHWDINEEPLKFQCDDAEVGTW
                     VYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTYDFVTFHQLENAFIPFNRNGVLFPRK
                     INGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAPFEDSAWQCTKIGAGP
                     IPIETSEGWLLIYHGVLASCNGFVYSFGSALLDIDQPWKVKFRSGPYLISPQKDYECMG
                     DVPNVCFPCAALHDSETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII"
     CDS             complement(9014..10282)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg95_10"
                     /sec_met_domain="MFS_1 (E-value: 2.7e-11, bitscore: 34.3,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKPISPVCWVPTVYFAMGLPFVALSMVSVLMFSDMEVSNAQIA
                     FWTSLIMLPWTLKPLWSPFLEMFKTKKYFVVATEIITGLAFALVALSLPLPDFFRYAIA
                     LMGIIALSGATHDIAGDGVYLTELTATQQAKYIGWQGAFYNLAKILANGGLVWLAGMLK
                     DEFGVIHAWMIVMLMCAGIMILIGLYHIRILPSGGGASGEVNTMSDALNMLWEVIRSFF
                     QKKHIAFYIVFIILYRFAEGYAIKIVPLFLKASVADGGLGLSTQDIGLVYGTFGAGAFI
                     LGSLLAGYYISAFGLRKTLFSLCCAFNIPFLVYFLLALYQPSDLWIIGMAIVSEYLGYG
                     FGFVGLMLFMMQQVAPGKHQMAHYAFATGIMNLGVMLPGMMSGYLSDWLGYRDFFIWVL
                     IATIPAFIVTWLVPFTYPDGKKK"
     CDS             complement(10532..11545)
                     /locus_tag="ctg95_11"
                     /transl_table=11
                     /translation="MNRHLNFVTLICLITGFVLLASCSNDDDEMDKYQKIYIRTGVAPG
                     AEMGAAVVVDCVSNSSTADRSDFEIQLCAVQPVTRDVTAALGVDTLKVDTYNSANKTKC
                     KLLPQDNYTIETSEVVLKTGQTVADSSFQVVLKNIEKLTNPDGYVLPVTLKGVTGMDEQ
                     AVSTSMKTVYIRIYTSVLYTSYTKPGNWSAVDRSAWSVSCSNVYADDDAKYGAHLAIDG
                     EINTTWFTWGVANAGECWWNTVLDRPVTLTGFSVTKQSAYGSGYNLRSAEIKVRKEGET
                     EWVTYPRVLTFRNFKGADPQYAAIEPPIPNVKEFRINCLTPDNYTGFAEINLYVKQ"
     CDS             complement(11568..12704)
                     /locus_tag="ctg95_12"
                     /transl_table=11
                     /translation="MKRITIKQYLLACFVLPMILAGCNDADYQVIDNAIYLNEASENGS
                     AKVTVDPENVTTTTLTVRVGQPVTENVTAVLTVDPSILKEYNEANETSYEVLPEQYFTY
                     DKEIKIAAGDVSAIPSEFRVKPYSNENGELYAIPVSLTEIQGPVSTIGLSSKFIILLDK
                     PLIQSVPFMNTTNAVKPAKDELWGVTTNEWSLEAWVQMDGFDINNQAIFNSGSSDHEVY
                     IRFGDAMIPYNSLQVKTLGSQVNTVTLFEKNKWYHLAFVYNSSGLLSIYINGVLDVTLQ
                     TKGGPVRFDKMNMVSSGSYFRNNCQMAQVRLWKSAISQTQIQSNMYFAVKPADPNLIGY
                     WKMDEGKGNAFADCTGHGYDLVAGGTLVWKEHVRFDKQ"
ORIGIN
        1 tgcaaaggta cgaatcattt tttaacttgc aaattattcc gcaaaaaaat attagaaaag
       61 tatatttgga agtaataact gctatctagc ttctccccat aaataggtat ttttatgcta
      121 ttcaacataa aataggaccc ttttatatac ctaaaccgaa aaaaggttgt aaatttgcgc
      181 gctctaaagg ataactaacc actaactgat taattttatg gaactgaata agacctttaa
      241 agatggactt tggagtaaag aaatcaatgt aagggatttc gttagtaaca acatcactcc
      301 ttatgaaggg gatgcttctt tcctgcaagg acctaccgaa cgcaccaaag ctgtctggaa
      361 tcactgtctc aaagctctcg aagaagagag aaacaataat ggtattcgtg cactcgacta
      421 cacaactgta tctactataa cctctcaccc tgccggctac atcgataaag agaacgaact
      481 gatcgtcgga ctacagaccg atcaggtgtt aaaacgtgcc atcaaaccgt ttggcggaat
      541 caatgtggtt atgaaagctt gccgtgaaaa cggagtggaa gtagatgaca gagttaagga
      601 tatcttcact cactatcgca agactcacaa tgatggggta ttcgatgtgt ataccgaaga
      661 aattcgttcg ttccgttcat tgggattcct taccggactt cccgacaact atgcacgcgg
      721 acgtatcatc ggtgattatc gccgcctggc tctctatggt cttgaccgtc tgatagaagc
      781 taaaaaagaa gatctgcata atctgacagg tcctatgact gaagcccgca ttcgtcttcg
      841 cgaagaagta gccgagcaaa tcaaggccct gaaagagatt aaagtattgg gcgaatatta
      901 tggtttggat ctgagccgac cggcatatac cgcacaggaa gctgtacaat gggtgtatat
      961 ggcttatctg gctgccgtaa aagagcagga tggtgctgcc atgtcactgg gtaatgtatc
     1021 ttcattcctc gacatctatc ttgaatatga attaagccag ggtacgataa ccgaaacatt
     1081 cgctcaggaa ctgatcgacc aattcgttat caaactccgt atggtacgcc acttgcgtat
     1141 gcagtcgtac aacgatattt ttgcgggtga tcccacatgg gtgaccgaat ctatcggtgg
     1201 acgtttcaat gatggacgta ccaaagttac taaaacttct ttccgcttct tgcagacact
     1261 ttataactta ggcccgtcac cggaacctaa catgactgta ctatggagcc ctgagttgcc
     1321 cgaaggtttc aaagcattct gtgcacaagt atctatcgac acttcttccg tacaatacga
     1381 aaacgacgac ctgatgcgtg aagtccgtca atcggatgac tacggaatcg cttgttgtgt
     1441 ttcatatcag gaaatcggaa agcagattca gttcttcggc gcacgtgcca accttgccaa
     1501 agccctgcta ctggctatca acggaggacg ttgcgaaaat acaggtacag ttatggtaaa
     1561 agacatccct gtattgaccg gtgaaacact gaagttcgaa gaagtaatgg ccaactataa
     1621 gaaagtattg atacaaattg cacgtgtata caacgaagca atgaatatca tacattacat
     1681 gcacgataag tattactacg aaaaggcaca gatggctttc gtggaaactg atccccgcat
     1741 taacctcgct tatggtgtag ccggactttc aatcgccatc gattcactgt ccgccatcaa
     1801 atatgcacat gtgaaagccc gtcgcaacga catcggactg acggagggat tcgatatcga
     1861 aggtgctttc ccttgtttcg gtaatgacga tgaccgtgta gaccacctgg gtgtagacct
     1921 ggtatatttc tttagcgaag aattaaagaa actccccgta tataagaatg cccgtcctac
     1981 cctctcgctg ctgactatca cttcgaacgt aatgtatggc aagaagaccg gtgccactcc
     2041 tgacggacgc gccaaaggca ttgcctttgc tcccggtgcc aaccccatgc acggacgtga
     2101 taaaaatggt gcaatcgcct cactgagttc tgtagccaag ttgcgttatc gcgactcaca
     2161 ggatggtatc agcaatacat tctcgatcgt tcccaaatca ttgggagcaa cacaagagga
     2221 ccgtatcgac aatctggtga ccatgatgga cggatatttt acaaaaggcg cacaccacct
     2281 gaacgtaaac gtgctgaacc gggaaatgtt gcaggatgcg atggaacatc ccgaaaagta
     2341 tccgcaactg actatccgtg tctcaggata tgccgttaat ttcgtgaaat tgagccgcga
     2401 acatcagttg gaagtaatca gccgcagttt ccacgaaaga atgtaattga atgataaacg
     2461 tacactcata cgagtcaatg ggaacattcg acgggccggg tctccggctc gtcgttttcc
     2521 ttcaagggtg taacttccgt tgcctctatt gtgccaatcc ggacacaatt gaagccaaag
     2581 gagggacagc aaccgatcct gaggaaatag ttcgcatggc cgtcagtcag aaagctttct
     2641 tcggtaaaaa gggaggtatc accttttccg gcggagagcc tacttttcaa gcaaaatcgc
     2701 ttatcccact ttttaaaaga ctaaaggaag caggaatcca tatttgcctt gataccaatg
     2761 gcgggctatg gaacaatgat gtagaggaac tattggaatt gactgatctg gttttattag
     2821 atatcaaaga atttaatccg gaacatcatc agtctttaac cggaagaagc aacgagcaga
     2881 ccctgaaaac cgcagcctgg cttgaaacca atcataaacc attctggttg cgatacgtat
     2941 tagtgcccgg ctacagtgac ttcgaagacg atatccggca gctgggagag catcttggaa
     3001 cgtaccagat gattcagcgt gtagaaatat tgccttacca caccttgggc gttcacaaat
     3061 atgaagcaat gaacaaagaa tatatgctga aaggagtgaa agagaatact ccggagcaga
     3121 tagaaaaggc tgagaaacta ttcaggcaat acttccggac cgtacaagtg aattgactta
     3181 tataagtgtc gaaattcgta ttcgccacag attacacgaa tttacacaga taaagattca
     3241 ttggcaatca acagattaag ttcattctgc ggtgaattat gacgactgca cttatttata
     3301 attttgtaag tcacgatata aaagtctccc tgttcttgcc ttaattcatt acaatacaag
     3361 gcaagaacag ggagataatg taaccggcat attttttgcc accctacttt aataagtgaa
     3421 tcgcaatcct gcctgcaagt taaagttaca aggcctttct tttcggatgg tttgtacttt
     3481 ggagccatca tcaaagaaat acgaaactcc cggttccaca tataggccga catgatctgt
     3541 cgcattgaat tgcgctccca cgacaccggc tacagaaaat tgcaaaggct tcacattcac
     3601 cttatcatcc gccaactttc cataaacaca cttttcaacc attcctccgg cagatacata
     3661 gagtgtaaaa tatttctttt ccagaaaatt ccagtttcca cgtacaggaa tacctatata
     3721 atgcaatttc tgactctgca tcttggtatc cccctgccgt ttgatgtcag aagacaacaa
     3781 cgtataagtc aatcccgtct ctacagagaa acctttggga agagacttac gtacagacag
     3841 tccgaagcta accggctgat gatgttcata atccaccacg gcagttgtat tggacttcag
     3901 gtaagggact ccttcttcaa atataacttc ctgatcggca ggaatactca cagctccatt
     3961 catgatcgtc atcaagtcga ccctgttagt catcggacgg ggcgcaaaat tttcggaacc
     4021 atttgtcgga agtccacctc cattaccgat acccactccc atcgaccatt taccaccacg
     4081 tttagcagaa gagtctccga taggcaactg atacttgtct ttaccggacg gtcgccgcgc
     4141 ttctttcctc tttggaggct gcgctgtcac actttctttt ttctcgattg ccgcagttgc
     4201 ttcctgttgc ggctcagctc tcttttcctc cgtcactgcc tccggttgct tctctgccag
     4261 ggaggatacc tccggaacaa tcaccggatc agtattcttt gccaaatagc ccgaaacagg
     4321 gttaatactc gtcgttccta ccggcttaac gggttcggat acagctacct gtacatccgg
     4381 caaggcaggt tccggcaata catccgggtt gacagccagt gaaggagccg ttgcataacg
     4441 gatttcatca gctaccggac tattcagaaa atacaaactg acagcagtcg ttaccaccaa
     4501 taccacagct gccgcagcaa ccgcccaccg gcgatacgga tatattcgtt tttcggttac
     4561 aggcatcagt tccctttcca gtcgttccca accggaagca ggcatcggct ccgaataatc
     4621 ttcgagctta tccttgaatg ctttaatcca tttttcgtct tctttcatca ttctatttca
     4681 tttttgaaat ccaaggttca cctcagtatc tgtaaataca tgtcaaccat tggtcaccaa
     4741 ccattctttc actttctttg ccaatacact ttttgcgcga aaaagctgtg aggcagaaga
     4801 tttttcatta atccccaaca tctgtgcgat ttccttgtgc gacttatctt caaaggtgta
     4861 taaattgaat acggtacgat atccggcggg gagttcatta ataaattgca tcagcacttt
     4921 ctgtggtatt gcttcaacag ccgaagcatc cggttcttca tacgtttcgg gaacttcatc
     4981 cagtgccgtg gtctggttca tcacgtcgtt ctttcttaag aactgtaaag ccgtattcac
     5041 cattacacgc tccatccatg ctctcagaga gccttcaccc cgccaggtaa acttgtcgaa
     5101 ggagtcgaaa atcttcagga aaccgtcgtg taccaagtct tgtgccatgt ccctgtctcc
     5161 ggcataacga agacagacac caagcatgcg ccctgcgtac tgctcataaa gttctttgcg
     5221 ggcacgatta tctccctgcc tgcaacgttc cgacagctct aattcattca ttctcctaaa
     5281 cacgtgttta ccttataaat gcagcaaaga tagaaatact gcacagagag aacaactctt
     5341 ttatcacttt tgtttcttta acattttagg atgcaatatt tcatcacttc ctgcattttc
     5401 tcaatacaat aaagaataaa tctcaatgga taaataggat aaaaccaaca agaaacttat
     5461 gaagaaattt aatttaataa cttttgccgt catcctgatg ttattgccca ttttacagtc
     5521 atgtctggac gatgccaaca acgacgagtg ggtcacttgt cctccgggtg gaatattggc
     5581 catcggcaca atgaagattc ccaatgcgga cactcccagg gactttttca ttgcattgga
     5641 caatggagac aatgtacttc cggcagatac ggccgatata cgcaacagga aatacactgt
     5701 tgcagaaggt caaagagtct tcgttggcta tctgcagatg ggagaagaga aacccggata
     5761 tgagaacggt aaaatattca cgatagaaga tatattgacg aaagagatca tcccactgac
     5821 ggaagctaca gcagacagca ttggagacga ccgtatcaac gtcacagcgc atgcacttac
     5881 gaaagattat ctgaccatcg aatatcaata tctgggcagc atgaatgaaa ataaaaaaca
     5941 catgctgaac ttggtacaaa acgaaataac aggtcccata aaagatgacg gatatatcta
     6001 tctggagttc cggcataatg cctttaatga ctcccccaat caattgggtt cgagccttgt
     6061 ttctttcaag ctggatagta tagccgagca attggcgaca gccaaaggaa taaaactccg
     6121 tgtgaacacc atttatgaca atatacagta tgtcacaata gatatcaacg aagacaaaaa
     6181 cttaaaaata aaatcatttc attctcaata aaacaacaag aaacacctac acaatcaggc
     6241 aaaacgagta ataattctga tacataaaag aaataaggcg gcgatgtttg tgaaaatatc
     6301 gccgtcgttt ttatattata ccagacactg aacggcctgc agggtaagca tctccttggg
     6361 aaccgccgcc tgaatctcct ctttcaaaac ctgcagcaga ctggtgcgga tgaagtcttt
     6421 ccgggtcacc aggacaatct gacgggtagg ccgcgggata gcaaacggac ggaccagttc
     6481 tttctgttct tcgctcaatt gcatcactgc cagttcagga ataaacgtaa tccccttacc
     6541 actctccacc atatgcataa aggtttccat actacccagc cgatacgcca tttggctgat
     6601 cttaaccgct tccatctgac aaaaacgaac caactgatcg cggaagcaat gcccttcgtc
     6661 aagaagccaa agccgttccc ctgtcacatc ggacgtacga atcacatcgt gcttgaacaa
     6721 cggttccttc tttgagacat agcccaggaa ttgctcgtag aataaggtct cttccgttaa
     6781 tgcggcatca tctagcatgc tggcaatgat agcagcatcc gcttcaccgg tcagcagagc
     6841 cttgcgaatg tcgggcgtct tcatctccat cacccgtata tcaagatccg ggtatttctc
     6901 catcagttgc ggaaagaaac ggggcagaag ataaggagca atcgtcggta acactgccaa
     6961 tcggaatgta cccgacaggg agtgctgttc ttcgctgatg atctccttga cacagataac
     7021 ttccgaaaga atcttacggg cctgttccag cactttctta ccaatggcag tagggcaaac
     7081 cggtgtcatg ctacggtcga acagtttcac ccccaattcg tcttccagct tttggatcat
     7141 tgcactcaaa gtaggttgcg tcacccggca atactcggca gctttagcaa aatgccggaa
     7201 ctggtcgaca gccagaatat attccaattg ttgtatagtc atcgttctct gatttattaa
     7261 agatatagaa tctatcaatg caaagataga aattttcagt ttgacacgaa tcattttgtg
     7321 ccgtatcttt gttccagata aaaagaagaa atatagtatt aactcaaaaa aaacaatatc
     7381 attatgaaga ctttaaatta tacacatttg gaagaaaaag gagctaacac catcgtactg
     7441 tcattacagc aactgcttgc cgattttcag attcattatg caaacctgag aggatttcac
     7501 tggaacatca aaggacacgg tttcttcgta ctgcacagca agtttgaaga tttatataac
     7561 ggagccgccg aaaaggtgga cgaaatagcc gaacgtatac tgatgctggg aggaactccc
     7621 gccaataaat acagtgacta tctgaagatg gcgcagatca aggaagtgga cggagtgaat
     7681 aaggccgacg acgctctgaa tcatattctc gaaacttacg ggcatctgat tgcggaagaa
     7741 cgtaaaatcc tgtctctcgc ctcttcacac aacgacgaag taacagtggc catgatgagc
     7801 gactacctga aagaacagga aaagatggtt tggatgctga ctgcatacaa cggataacag
     7861 ccgaaagggt gtagccatct gaccgaaaag gtgtagccat acaaacaaaa gggtgtagcc
     7921 atcccggcgg gatagctaca ccctttctgt tttattcgat tcagatgata cttgtacgtt
     7981 tggtaaattc aataatctcc ggaatgtatc cgaatgcgag cccggtcact gtatccgcac
     8041 acccataata gatggcaatc cgtccggtct ccgaatcatg aagcgccgcg catgggaaac
     8101 agacattagg cacatcaccc atacattcgt aatccttctg aggtgaaatc agataaggcc
     8161 ccgaacggaa ttttactttc cagggttgat cgatgtcaag cagtgccgaa ccaaaactat
     8221 acacaaaacc gttgcaggaa gccaatacac catgatagat cagtaaccag ccttccgagg
     8281 tttcaatcgg gataggccct gcaccgatct tggtacactg ccaggcactg tcttcgaacg
     8341 gagccggcga cataacatga cgatgacgtc cccagaactc catatcggga gactcgctat
     8401 agaaaatatc tccaaaagga gtatgcccat tatcactcgg gcgactcaac atcgcaaaac
     8461 gaccgtttat cttacgaggg aacaagactc cattccgatt gaaaggaata aaggcattct
     8521 ccaactggtg aaaagtaaca aaatcatagg tgtaggccac accgatagta ggaccatgat
     8581 agccattaca ccaggtcaca tagtagcggt cttcgataaa gcaaacccgt ggatcatatc
     8641 catagaccca ggttccaacc tcagcatcat cacattgaaa ctttaacggt tcttcgttga
     8701 tatcccaatg aacagcatcc ttgctgaatc ccacatgcaa acgcatgcga cgattagtat
     8761 catcacaacg gaacacccct gcatagccat ccttaaacgg aactacggca ctgttgaata
     8821 tactgtttga agtagggagc aagtcgcgcg gaataatcgg attgaccgaa caacgccaca
     8881 ctacatcttt acatcctgcc ggacgttctt cccaaggcat agccggcaaa gcagcacctg
     8941 caattttaat ttcttccatg attcgattaa attaatatta tgtatatatc ttgtttatat
     9001 tgaaaatctc tttttatttc ttctttccgt ccggatatgt gaaaggtacc agccaagtca
     9061 cgataaaagc cggtatggta gcgataagta cccagataaa gaaatcgcga taacccagcc
     9121 aatcgctcag gtatccgctc atcattccgg gaagcatcac ccccagattc ataataccgg
     9181 tagcaaaagc ataatgtgcc atctgatgtt tgccgggagc cacttgctgc atcataaaga
     9241 gcatcaatcc gacaaaacca aacccgtaac ccaagtattc agacacaatg gccataccaa
     9301 taatccatag atcggaaggc tggtaaaggg ctaacaggaa atataccaag aacggaatat
     9361 taaaagcgca acataaagaa aacaaagtct tccgaagtcc gaaagccgaa atgtaataac
     9421 cggccaaaag cgaaccgaga ataaaagctc ccgctccgaa cgtaccatat accagtccga
     9481 tatcctgagt gctgagtccc aatccaccat ccgcaaccga cgctttcagg aacaacggta
     9541 caatcttgat ggcatatcct tcggcaaacc ggtacaaaat gataaagaca atgtagaaag
     9601 caatatgttt tttttggaaa aaagagcgga tgacttccca aagcatattc aatgcgtcac
     9661 tcatcgtatt cacttcaccg gaagcgcctc ctcccgaagg caaaatccgg atgtggtaaa
     9721 gaccgatcag aatcataata cccgcacaca tcaacatgac aatcatccag gcatgtatca
     9781 ctccaaattc atccttcagc atacctgcca gccaaaccaa gcctccgttg gcaagtatct
     9841 tggccagatt ataaaaagct ccctgccaac cgatatactt ggcttgctgg gtagcagtca
     9901 gttcagtcag gtatactccg tcacccgcaa tgtcatgagt cgcaccactg agagcaatga
     9961 tccccatcag agcgatggca taacgaaaaa agtcgggcag cggcagcgaa agtgctacca
    10021 atgcaaatgc cagtccggta atgatttccg tagcgacaac aaagtatttt ttcgttttaa
    10081 acatttccag aaacggactc cataaaggct tcaatgtcca gggaagcata ataagagaag
    10141 tccagaaagc aatctgtgca ttcgacactt ccatatcgga aaacataagg acagaaacca
    10201 tcgaaagggc cacaaacggc aatcccatag caaagtaaac agtaggcacc caacatacag
    10261 ggcttatcgg ctttttattc atcagttagt tttttataat aattccatcg gttaacaatt
    10321 ccagtaagca aagatagggg atattaaaaa cataacccaa gattacgaca agaagttgct
    10381 ttcattattt aataatacaa ctcacccggg aaaactacta acctctatca cccttttttt
    10441 attaaacttt atcaatacaa tacacgcaaa gaagcaccga agactttcat ccccgatgcc
    10501 tctcgccccc ttatctacaa tctaaacacc tctattgctt cacatataaa tttatctcag
    10561 caaacccggt ataattatcc ggagtcagac agtttattct gaattccttt acattcggga
    10621 taggtggttc gatggccgca tattgcggat cagccccttt aaaatttctg aaagtcaaga
    10681 ctctcgggta agtaacccac tcggtttcac cctctttccg aaccttaatc tcagcacttc
    10741 tcagattata acccgatccg taggcactct gtttagtgac cgaaaatccg gttaaggtaa
    10801 caggccggtc cagtaccgta ttccaccaac actctccggc attagccact ccccatgtaa
    10861 accaagtagt atttatctca ccgtcaatag ccagatgtgc accatatttg gcatcatcat
    10921 cggcataaac attgctgcaa cttacactcc acgcacttcg atctacagcg gaccaattcc
    10981 cgggtttcgt ataactggta taaagcacgc tggtataaat ccggatataa accgtcttca
    11041 tagatgtact gacagcctgt tcgtccatgc ccgtaactcc tttaagcgtc acgggaagca
    11101 catatccgtc aggattagtc aacttttcta tattcttcaa aacgacctga aaagatgaat
    11161 cggccactgt ctgtcccgtt tttaagacaa cttcacttgt ttcaatggta taattatctt
    11221 ggggcaacaa cttacatttc gtcttattgg cagaattgta agtatccact ttcagcgtat
    11281 ctactcccaa agcggcagtg acatcccgcg taaccggctg tacggcacac aattgtattt
    11341 caaaatcaga acggtcggca gtagaggaat tgctcacaca atccaccact accgcagcac
    11401 ccatctcggc ccccggtgca actcccgttc tgatatatat cttttgatat ttgtccattt
    11461 catcatcatc gttgctgcac gaagccaaca atacaaagcc tgttatcagg cagattaagg
    11521 tcacaaaatt caaatgtcta ttcatatctt atcttctttt tacatagtta ttgcttatca
    11581 aaacgaacat gctctttcca gacaagagtt cctcctgcca ccaaatcgta tccgtgtccg
    11641 gtacagtcgg caaaggcatt tcctttacct tcatccattt tccaatagcc tatcaggttc
    11701 ggatcggcgg gtttcacggc aaaatacatg ttggactgaa tttgcgtctg gctgattgcg
    11761 ctcttccaaa gacgcacctg ggccatctga caattgttgc ggaagtagct accgctcgaa
    11821 accatgttca tcttgtcgaa tctaaccggg ccaccctttg tctgcagagt cacgtcgagc
    11881 actccgttga tataaatcga caataacccg gaagaattat aaacgaaggc cagatgatac
    11941 cacttattct tctcaaacaa agtcaccgta ttgacctgac ttccaagtgt cttcacctgt
    12001 aatgaattat aagggatcat agcgtcaccg aaacggatat aaacctcgtg gtcgctgctg
    12061 cccgaattaa atatagcctg attattaata tcgaatccgt ccatctgtac ccaagcctcg
    12121 agtgaccatt cattggttgt cactccccac aattcgtcct tggcgggctt cacggcattg
    12181 gtcgtattca taaacggtac agactgtatc agcggcttat ccagcaaaat gataaacttc
    12241 gacgaaagcc cgattgtgga caccggtccc tgaatttctg tgagagatac cggaatagca
    12301 tacaattctc cgttttcgtt tgaataaggt ttcactctaa actcactggg gattgcgcta
    12361 acatcgcctg ccgctatctt tatctctttg tcataagtaa aatactgctc gggaaggact
    12421 tcgtacgaag tttcattagc ttcattgtac tctttaagaa tagaaggatc taccgtcagg
    12481 acagcagtca cattttcggt tacaggctgt cccacacgta cggtcagagt agttgttgtt
    12541 acattttcag gatcaacggt aacctttgcc gaaccattct cggatgcttc attcaaataa
    12601 atcgcattgt cgataacctg gtaatcggca tcgttgcatc ctgccaggat catcggcaga
    12661 acgaaacagg caagcaaata ttgttttatt gttattcttt tcataatcaa attctttaaa
    12721 gtcattttac agcaggattc attattctga ttgcttcacg caggtactta tattcgatgt
    12781 cgcccggata gtcatattcc atgtgatagg tgcctactcc acccttccgt acctgttttc
    12841 cgtcaatagt cggagtccag cgtgccatgc cggcaagtgc tctcattttg tttccgtaac
    12901 gatctacata atcacctcct cctgtcggag cataagattc gaaattctcc gtaacgatgt
    12961 acatattagc cactttctcc ggaggaagta ttcctttaaa gttggcaatc gtaccagcca
    13021 gacgtctgtc aagattagcg tcggaattac ccgcaaggtt agagtatgcc tgcacaatga
    13081 aatagtcaaa gtaaggcccg gtttccggat gaatactttg aggctcgcca tcaatcacaa
    13141 gtaaccgtcc cgtacccgat ttaggtccga ttcttt
//
