LOCUS       c00097_gnlPro..        14831 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CKKHKCMJ_97.
ACCESSION   c00097_gnlPro..
VERSION     c00097_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 13:21:18
            Original ID  :: gnl|Prokka|CKKHKCMJ_97
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14831
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14831
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1391:4831]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1392..4831
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14831
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14831
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             37..1068
                     /locus_tag="ctg97_1"
                     /transl_table=11
                     /translation="MKIGTIDLGERPVFLAPMEDVTDISFRLMCKRFGADMVYTEFVSA
                     DALIRSVNKTQQKLNVADEERPVAIQIYGRDVPTMVEAAQICEAAHPDILDINFGCPVK
                     RVAGKGAGAGMLRNIPLMLDITREVVKAVNIPVTVKTRLGWDADNRIIVDLAEQLQDCG
                     IAALSIHGRTRAQMYTGEADWTLIGEVKNNPRIQIPIIGNGDVTSAEICKQRFEQYGVD
                     AVMIGRGSIGRPWIFREVRHYLDTGETLPAESFSWYLDILKKQVEQSVERLDERRGILH
                     IRRHLAATPLFKGIADFKQTRVAMLRAETVEALFDILDSIPDKFHTGYGFQSDSQVSES
                     IDC"
     CDS             complement(1041..1199)
                     /locus_tag="ctg97_2"
                     /transl_table=11
                     /translation="MKKTHCKYKVYLLNTQEFVITFYCKFATFCFKIDTVCGFTLLLYQ
                     QSIDSDT"
     CDS             complement(1196..1381)
                     /locus_tag="ctg97_3"
                     /transl_table=11
                     /translation="MYVYGKARRQWQRAFFMFVQTHKKAALPIIKVDAAFLLLSSETVS
                     RFPLCKDFVNLRSKIL"
     CDS             complement(1392..2147)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg97_4"
                     /sec_met_domain="Fer2_3 (E-value: 2e-26, bitscore: 83.0,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 5.8e-12, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.2e-06, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKGPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANAIPISKADADLAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFISAKLQD"
     CDS             complement(2175..4118)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 194.4; E-value:
                     1.1e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg97_5"
                     /sec_met_domain="FAD_binding_2 (E-value: 4.8e-60, bitscore:
                     194.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3.1e-38,
                     bitscore: 121.5, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQIDSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKIERFAAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDFQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNSTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFVEAEKAINARIAKLMNVKGKETVDSIHRKLGHI
                     MWEHVGMARDAEGLKEAIQMLKDLKKEFWSNVFIPGEANSLNVELDKALRLADFIEIGA
                     LMAHDALDRAESCGGHFRTEHQTEEGEAMRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     QFVVPQTRNYKK"
     CDS             complement(4157..4831)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg97_6"
                     /sec_met_domain="SucD_FumR (E-value: 2e-67, bitscore:
                     217.4, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLILFLVFHLCMNIAAVFSGEAYNVI
                     CGLLGSNWYALLGTLVLAAGVVVHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGVIVILFMVLHFTQFWYNMMFAELAGIHGDIHPQDGAAFINFYFQGNVVNTVLYL
                     IWFVALWFHLTHGFWSAIHTIGWNNTVWLSRWECISKWVATIICGLFAVITVIFYLNGV
                     GA"
     CDS             5091..6044
                     /locus_tag="ctg97_7"
                     /transl_table=11
                     /translation="MKTAIFSIGVFLISLFLGSCQPSETSCSVVDTGKTLDYKIGDKLL
                     FSYNYTTVYPAPGVDSVYKRSGFIHPLKTLGGEVMTNCSPADHYHHFGLWYAWTKTTFE
                     GNEIDFWNLHKKQGTVRFRNFEHVSDNGFVATLDHVVYPDSPAEKVAMNERLEINIGTT
                     SLPGYYIDYHTTIRLASPSPITMEAYRYGGICIRTREDWNDQTAEMLTSEGLSRDEADG
                     SRARWCYYQGKAGNEKACILIVASPSNLNYPEPLRVWDKTVNKPAGDVMWNFSPTKQKA
                     FTLEPGKELSLSYRIYVLDKNINATTAEVLSDFERD"
     CDS             7101..10382
                     /locus_tag="ctg97_8"
                     /transl_table=11
                     /translation="MLKKTKLVSLMLLAGTLAVPESAFAEITPERPSVSLSQQNGKVVC
                     VVEDSFGPVIGASVVVKGTTNGNVTDMDGKVVLENLKKGDIIQISYIGYATQEITYTGQ
                     PSIPVTLKEDTQALQEVVVVGYGTQKKENLTGAVAAVAGDVLENRPITNVGQGLQGVVP
                     NLNVTMSKGGAPGSSSDFNIRGNNSINGGSPLVLVDNVQMDANLVNPEDIASISVLKDA
                     ASAAIYGARAAYGVILITTKKGKSEQKPQISVSASGYWQSPALRMHNINSLEYLEMRDI
                     AAANSGMSSLITPGQLDYVKKYMDGSYKYSEYFDQSQDQSRWIYCGNTDWFNELYKTSF
                     SQQYNVNISGGDSKTTYYGSVGFADQNGILKTADDNYKKFNATLNLSSQLTKWLQVSAK
                     IADNYSTEDHPITNSTAGIDAYGGMLKNDLSPLMPVRFGHTGRLVYSPGAAAINDSNLG
                     IQTSGDYIYKEEGINNYSGQNGNTNPAAVGDLGGYTKYKINDLWLTGAVKITPLEGLVI
                     NADYTYNIYSKNASEVQRTFTDYTAVAGTEALYGWTKPSYANYTTNEDYYYAFNAFAEY
                     SKSFLENTHNFKIMAGYNQEKKSNKKYNAKRTNLIVEDIPDLDLATGEQSMSSEDTYWA
                     INGFFFRFNYNYKQRYLLEVNGRYDGSSKFAKDHRYAFFPSVSAAWRISEENFWQPLKG
                     WWNDMKIRGSYGSLGNQVMDDLGNFPYLATYGTNSSYNYLINGSKPVIVKAPGLVAPDF
                     TWETVTQMDFGFDASFLNNRLTGTFDWYRRNTKDMLVAGATLPATLGASVPKSNSADMK
                     TIGWELSLGWNDRLENGFSYWVKGVLSDYQATITKYAGNDAGFYSQSDDDGKYYVGQKI
                     GEIWGYHSNGLFQSDDEAATIDQSELYAGKWGAGDVKYEDLDNDGKITKGEETIYNPGD
                     KSIIGNKTPRYQFGITVGFDYKNFDFEMFWQGTGKRDYMLSGAQFWGFTSQWDVPYTPA
                     LDYWTETNTDAYFPRPGWQNGGNRVTSDRYLQSAAYGRLKNLTVGYTIPKNLTTKWGIS
                     RLRLYVTGENLLTITPLNDAFDPETLGGMTYPINRKVAIGLNLTL"
     CDS             10393..12252
                     /locus_tag="ctg97_9"
                     /transl_table=11
                     /translation="MTMKTKHILLGLSLGLLGGFTACDVTDLNPKDSITDNSYWNTVSD
                     LENYAKGFYMNLTGKGLRADGSENLDDLNTLDERSDNRLVASPDQWLFNEWVIPSEANF
                     DSKWYWNNIRNLNYFMTRYQRVNATESEVNPVVAVIRFFRAFDYFDKIKTFGDVPWYEK
                     DLTTADIDELYKARDDRDFVLGKIIEDLEFAIEWLPEKSAAEVGALHKDAARTFLARVC
                     LHYGTYKKYHNVSTSPTSQELLQKAATLAKEVMDSGLYDIVQGSDAGANQSAFADYPLY
                     YANQFTQEDLTTNKECILARVFEADVLTHNLARGGGVGLSKDFAESFLCKDGLPIANSS
                     EYKGDETLDDEMANRDPRMYQIIDSKYRPYTVKSNGMRVVNSGIDDKKEFSPSEEPGTN
                     IHSAPGLTGTATGYSPIKLVSASQSQQDAVKTSSYDWFVFRYAEILLIYAEAKCELGEC
                     TQAVLDETINKLRDRVEMKHLTVSPVADLNPVDYGYSITPLLYEIRRERRIELALEGFR
                     YDDIMRWNAMKLFENPKTYLGMRVTDKVKALYQPEVFEGSTARDLIEYNGKTYIRMYSG
                     KSLNEAGRKWTGNDKRLYYPIPTSQITLSASHGSLLKQNPGWE"
     CDS             12432..14213
                     /locus_tag="ctg97_10"
                     /transl_table=11
                     /translation="VFKTGFYMNKKDLILNILLFISQIIVFYYFFCYLFPFKEQLQMFQ
                     FTSQYLTETLKQAGGVAIYISEFLSQFYVVFWTGPIISALLLTLVALLSSLILKKINSR
                     NDLPLIFLLPWLSLLIISLDYDYYEQGTIAYLFLLLFLWLYTNIKTRIKFIYGICIIPI
                     LYGIAGPIVHLFAISALFFEFLTNGKKKYISIIYLLIAALSAIAGTYLGYSRNLTLAFL
                     PEAYCNPLQTVSGIYYAWYALPMTMLLVAYLKRYKEPVSLKGKCIWEGAQWAIMFLLVY
                     QGIFHFGKLDAQHSMKQDYLLRTEQWDLVISEFNHDVLSKRRMCGLNLALAHKGQLSER
                     LLDYPQHGIETLMLHWDQSIYTAQLHSDLYYCMGIISAAQKFAFEAFVSSRSSGNPRML
                     KRLIETNLITGSYPIADKYIQLLEKTWFYKDWATAHRRFLYNDKAVEEDKILGMKRRCW
                     KAEASAAKLYTDPVSSLINLLPACPDNKAGLAYLTSFLLLNKDIETYKTLQESLYRSPA
                     WRDMTECQQEAIVICSPNDPHFWLEHGVSIKVRNRAIAFMQKVQDISRSGQNPAVALAS
                     EYDKTYWYYYMFNMMDK"
ORIGIN
        1 atcagtacct ttgtccccgt cattgataat ataaatatga aaataggtac aatagattta
       61 ggcgaacgcc ccgtcttctt agctccgatg gaagacgtta cagatatttc tttccggttg
      121 atgtgcaaac gttttggtgc cgatatggtt tataccgaat tcgtttcagc agacgcccta
      181 atccgcagtg taaataaaac acagcaaaag ctgaatgtgg cggatgaaga acgtccggtc
      241 gccatacaaa tatatggccg tgatgttccg acaatggtcg aagccgcgca aatttgcgaa
      301 gccgctcatc cggacattct cgatatcaat ttcggttgcc ctgtcaaacg agtggcaggc
      361 aaaggagcag gcgccggcat gctgcgcaat attccactga tgctggacat cacccgtgaa
      421 gtcgtcaaag cggtgaacat ccctgtcacc gtaaaaaccc gcttgggctg ggatgccgac
      481 aaccggatca tcgtagactt ggccgaacag ctacaggatt gcggtatcgc agccctttcc
      541 atccacggac gtacccgggc acagatgtac acaggagagg cagactggac actgatcggt
      601 gaagtaaaaa acaatccccg tatacaaatt cccatcatcg gcaatggcga tgtgacttcc
      661 gccgaaatct gcaaacaacg tttcgaacaa tatggcgtgg atgccgttat gattggccgg
      721 ggcagcatag gccgcccctg gattttcaga gaagtgaggc attatctgga tacaggcgag
      781 acattgcctg ccgaatcttt ttcatggtat ctggacatac tgaaaaagca ggtggaacaa
      841 agcgtggaac gtttggatga gcgccgggga attctccaca ttcgccgcca tttggctgca
      901 actccgctgt ttaaaggtat tgcagacttc aagcagacac gcgtcgccat gctacgtgcg
      961 gaaacagtgg aagcattatt cgacattctg gattccatcc ccgacaaatt tcatacagga
     1021 tacggatttc aaagcgactc tcaagtgtca gaatcgatcg attgttgata taataacagt
     1081 gtgaatccgc acacagtgtc aattttaaaa caaaaagtag caaatttgca ataaaatgta
     1141 attacaaact cttgcgtatt cagtaaatat actttatatt tgcagtgagt ttttttcata
     1201 gtattttaga tctaaggtta acaaagtctt tgcagagagg gaatcgagag actgtttcac
     1261 tggaaagcaa caaaaaagcc gcatccactt ttattatagg gagtgcggct tttttgtggg
     1321 tttgaacgaa cataaagaaa gcccgttgcc attggcgacg ggcttttcca tatacataca
     1381 tatataatgt attagtcttg taacttagca gagatgaact cgcggttcaa gcgagcgatg
     1441 ttgctaacgg agatgttctt cggacattcc atttcgcaag cgcgagtgtt cgtacagtta
     1501 ccaaagccca gttcatccat cttagcaacc attgcttttg cacgacgagc agcttccacc
     1561 ttaccctgag gcaaaagagc cagctggcta acctttgcag agacgaacag catagctgaa
     1621 ccgttcttac aagcagcagc acaagcaccg cagccgatac aagcagcagc atccatagcc
     1681 aaatccgcat cagccttaga aataggaatt gcattagcat caggaacccc acctgtgttt
     1741 acagaaacga aaccacctgc ctggataatc ttatcataag cataacggtc taccatcaag
     1801 tcgcggatta ccgggaaacc agcagaacgc cacggctcga tcgtaatcgt ctcaccatca
     1861 ttgaaacggc gcatatagag ctgacaggtt gttgcacctg ttgccggtcc gtgcggatgt
     1921 ccgtttacat acaatgaaca cataccgcag ataccttcac ggcagtcgtg gtcgaatacg
     1981 ataggttctt tgccttcgct aaccaaacgt tcattcaaaa tgtctaacat ttccaagaaa
     2041 gaaacactct gattgatttt gtcgatttgg taagtctcaa actgtccttt atctttcgga
     2101 cctttctgac gccaaacttt aagtgttacc tttatatctt tatccatgat tctaattttt
     2161 gtgattgatg attattactt cttgtagtta cgtgtttgag gaacaacgaa ctgatagttc
     2221 aaatcttcct tcagcataac cgggtctttg tcttcaccct ggtattccca acaagagacg
     2281 tacatgaact tatcgtcatg acgcatagct tcgccttctt cggtctgatg ttccgtacgg
     2341 aagtgaccac cacaagattc tgcacggtct aacgcatcgt gtgccatcaa cgcaccgatt
     2401 tcgataaagt cagccaaacg caatgccttg tccaattcca cgttcaagct attggcctca
     2461 cccggaatga atacattgct ccagaattcc ttcttcaggt ctttcaacat ttggatagct
     2521 tctttcaagc cttccgcgtc gcgtgccata ccgacgtgtt cccacatgat atgtcccagc
     2581 ttacggtgga tagaatcgac tgtttcttta cccttcacgt tcatcaactt cgcgatacgg
     2641 gcgttaatag ccttttctgc ttccacaaat tcaggcaggt cagtgctaaa gcgcggaacc
     2701 tggatctggt cagacagata gttctggatc gtgtaaggca atacgaagta accatcggcc
     2761 aatccctgca tcaaagcaga agcacccaga cggttagcgc cgtggtcaga gaagttggct
     2821 tcaccaattg cgaacagccc cggaatagaa gtcatcaatt catagtctac ccacaaacca
     2881 cccattgagt agtgcaatgc aggataaatc atcatcggag tttcgtacgg atcatcgttc
     2941 gtgatctctt cgtacatatc gaacaggtta ccatatttct gtttaaccac ttccttaccc
     3001 agacggttga tagcatcgga gaaatccagg aatacagcca agcccgtgct atttacaccg
     3061 aaaccggcat cacaacgttc tttagcggca cgtgaagcca cgtcacgagg aaccaagtta
     3121 ccgaatgccg gataacgacg ttccagatag tagtcgcgat ctgcttcagg aatatccttt
     3181 cccttttttg ttccggcctg caatgccttc gcatcttcca gcttcttcgg aacccagata
     3241 cggccgtcgt tacgcagtga ttctgacatc aaagtcagct tagactggaa gtcacctttc
     3301 accggcacac aagtcgggtg gatctgcacc atacaaggat tagcaaagta agcccctttc
     3361 ttgtagcact gccatgcagc agaaccgtta gacgccatcg cgttagtaga caagaagaat
     3421 gtatttacat aaccacctgt cgcaacaacg actgcgtgag cggcaaaacg ttcgatctta
     3481 ccggtaatca aattacgggc aataataccg cgagcacgtc cgtcaacctt cacaacatcc
     3541 agcatttcat ggcgtgtgta catcttcacc tttcccaaac caatctgacg actcaatgca
     3601 gagtaagcac ccaacagcag ctgctgtccg gtctgaccac gagcatagaa cgtacgggat
     3661 acctgagcac ccccgaatga gcggttatcc aacagaccac catattcgcg agcgaatggt
     3721 acaccctgtg ctacgcactg gtcgataata gagtttgaca cttcagccaa acgatagacg
     3781 tttgcttcgc gggcacggta gtcaccacct ttgattgtat cgtagaacag acgataaacc
     3841 gagtcaccat cattctgata attctttgcc gcattgatac cgccctgtgc agcgatagag
     3901 tgtgcacgac ggggagagtc ctgaatacag aaattcaata cattgaatcc catttcagcc
     3961 agagaggcag cagcagaagc acccgccaga ccagtaccta ctacaattat gtccaaacga
     4021 cgtttgtttg cgggattcac caatttctgg tgatttttat aatttgtcca cttctcagcc
     4081 aacgggcctt gaggaatttt agaatctatt tgagtcataa tgttttattt tcaaattgaa
     4141 aaaataatat ccgaaattaa gcacctacac cgttcaggta gaagataact gtgataacag
     4201 cgaataagcc acaaataata gtggcaaccc atttagagat acattcccaa cggcttaacc
     4261 aaacggtatt gttccagcca attgtgtgaa tcgcagacca gaaaccgtga gtcaggtgaa
     4321 accacagagc aacgaaccag atcagataca acaccgtatt cacaacattg ccctggaagt
     4381 agaaattgat aaacgctgca ccatcctgcg gatgaatgtc accatgaata cctgccagtt
     4441 cggcaaacat catgttgtac cagaactgag taaagtgcag aaccatgaac aggataacga
     4501 tcacacccaa aacaaacatg ttctgagaag cccattcaac acctttcgga cgagcgttga
     4561 tggcataacg gtcgttaccg cgagccttac gattctgcag agtcaagata atagcataca
     4621 cgaagtgcac gactacacct gcagccaaca ccaatgtacc gagcaaagca taccagttag
     4681 aacccagcaa accgcaaatc acgttatacg cttcaccaga aaatactgcc gcaatgttca
     4741 tacataagtg gaacaccaag aacagaatga gaaaaagacc tgatatactc attatcagct
     4801 tcttcccgat agaagaatta agtaaccaca taagataata atttaagtta tttaattgta
     4861 tttagaaatt tcctccaatc tatggttatt atcgtgcaaa ggtatgctaa atccccatat
     4921 cacgcaaacg attaaagaaa tatttcatca attagaacgc tgcttgctgg ctggttttat
     4981 ttgcatcaga tatcacaaac ggattgtgcg aaacgaaaaa atttcgtttt tttgtagccg
     5041 atacaggcaa ggtcttgccg gataactgat tattatttaa ttgtcatatt atgaaaactg
     5101 ctattttttc tattggtgtt tttttgattt ctctgttctt aggctcttgt cagccttccg
     5161 aaacatcctg ttccgtcgtc gacacgggga aaaccttaga ctataagata ggagataaac
     5221 tgttgttctc ttacaactat accacggttt acccagcccc tggcgttgac tcggtctata
     5281 aacgcagcgg tttcatccat cctttgaaga cattgggagg cgaagtgatg accaattgtt
     5341 ctcccgccga ccattaccat catttcggtt tgtggtatgc ctggacgaaa accacgttcg
     5401 aaggaaacga gatcgatttc tggaatctcc acaaaaaaca aggaacagtt cgcttccgca
     5461 acttcgaaca cgtatccgac aacggttttg ttgcgacact ggaccatgtg gtctaccccg
     5521 attctcccgc agaaaaagta gcaatgaacg aacgcctgga gatcaacatc gggacaacat
     5581 ccttaccagg ttattacatc gactatcata ccactatccg cctcgccagc cccagcccga
     5641 tcaccatgga agcttaccgt tatggcggca tatgcatccg tacgcgcgaa gactggaacg
     5701 atcagacagc cgaaatgctc acctcggaag gcctttcccg cgacgaagct gacggttcga
     5761 gagcccgttg gtgctactac caagggaaag ccggaaacga aaaggcctgt atcctaatcg
     5821 ttgcctcccc ttccaaccta aactatcctg agcccttacg cgtatgggac aaaactgtca
     5881 acaagcctgc cggtgacgtc atgtggaatt tctcaccgac caagcagaag gcattcacat
     5941 tggaacccgg taaagaactg agcctgtctt accgcattta tgtattggac aagaacatca
     6001 acgctactac ggcagaagtg ctgtccgatt tcgaacgtga ttgaatttct actaaaacaa
     6061 actgacaatt tgcagggcaa ggtaaacaag aaaaggaaaa agggcttgtt ctcctatatc
     6121 atcaaagaca aggctctttt atgtaaatac agctacaaat caatgaaaaa cacgtaataa
     6181 aacttaccca acacccccat gtatccgccc ccgacacccg gatctataag agcgtaagat
     6241 ccgggtgtcg ggggcggata catgggggtg ttgataaaat tgtctcccta cttttacctt
     6301 aaaatgcttg gagtttattc atttaaaaca gatagatgag cgattacaga tagtgataga
     6361 agcgtgatat ataaaacagg tatctatcac ttcagatacg cactgattat caagactcac
     6421 acgacattta gtgatagagt gacagatgtt catgaaaaaa catcctagaa atcaccccat
     6481 cccgactact gagcttcaat aaagttgcac taaaattaga taaattaaca caggcattgt
     6541 atttcattgc ctattgccct tttcccagtt tttcgacaga tacaaaatca tgttctgtgc
     6601 tgatgagaat atgcataacc acaaaacttt cagacaaata tgcaatatta taaaaataag
     6661 attatttttt gaccacccat gcacagaaag agatataagt tctatcagaa ctatggtttt
     6721 taattatctc atatccgggt caaaggtatg aaattttcat ttcgttgtat gtttttttat
     6781 taaaaaagtt catatagcac tcatttttaa caattcagac ttacaggcta ccaacaagca
     6841 tcagacaata tcagactttt gaaccttttt aagcacaaga agtaatttgc ggcttatcat
     6901 tcaactctat ttttgtacaa tattcacact tatcagatac atttcttcat aaatacatga
     6961 gttctgatag aactaaatta caaaaacaca gaaaaacgct ataaaaatat gcaaaatcta
     7021 atgagcatga tctaataaag acactcaaca gatgtaagcc gttttcgtgg tatgtattat
     7081 ttcttttaaa tatatactct atgttgaaaa aaactaaatt agtaagtctg atgctactgg
     7141 caggaacttt agctgttcca gaaagtgctt ttgccgaaat tactccggaa aggccgtcag
     7201 taagtctatc ccaacaaaat gggaaagtag tatgtgtggt ggaagattcg ttcggccctg
     7261 tgatcggagc ttcagttgtt gtaaaaggaa caaccaacgg aaatgtgaca gacatggacg
     7321 gcaaagttgt tttggaaaat ttgaagaaag gagatattat tcaaatttct tacattggat
     7381 acgcgacaca ggaaataacc tatacaggac aaccgtcaat ccctgtaaca ttaaaagaag
     7441 atacccaggc gctacaagaa gtagtagtag taggttacgg tacacagaaa aaagagaatt
     7501 tgacaggtgc tgtggcagct gttgccggtg atgtactaga aaaccgtcct ataacaaatg
     7561 ttggacaagg attacaaggt gttgttccaa acttaaacgt caccatgagt aaaggtggtg
     7621 ctcctggtag tagctctgac tttaatattc gcggtaacaa ctcgattaac ggtggtagcc
     7681 ctttagtgtt agttgataat gttcaaatgg atgccaacct tgttaatccg gaggacatcg
     7741 cgtctatttc tgttttaaag gatgccgcat ctgctgctat ctacggtgcc cgcgctgctt
     7801 atggcgttat tttaattaca acaaagaaag gtaaaagtga acaaaaacct cagatttccg
     7861 tatcagcaag tggctattgg cagagccctg cattaaggat gcacaatatc aactctttgg
     7921 agtatctgga aatgagagat attgctgccg ccaatagcgg gatgagctcc ttgatcactc
     7981 cgggacaatt agactatgta aagaaatata tggatggctc ttataagtat tcagaatatt
     8041 tcgatcagtc gcaagatcaa agtcgatgga tttattgtgg caacactgat tggtttaatg
     8101 aattgtacaa aacaagtttc tctcaacaat ataatgtaaa cattagtggt ggagactcaa
     8161 aaacaactta ttacggctct gtcggatttg ctgaccagaa tggtatttta aaaacagctg
     8221 atgataatta caagaaattt aatgcgacac tgaatctttc ttcacaactg acaaagtggt
     8281 tgcaggtcag tgccaaaatc gcagataatt attcaacaga ggatcacccc attaccaact
     8341 ctacagctgg aatcgatgcc tatggaggta tgttgaaaaa tgacttaagc ccgttaatgc
     8401 ctgtacgttt tggccataca ggaagactcg tttatagtcc tggcgcagca gccatcaatg
     8461 attctaactt aggtatccaa acttcaggcg attatatcta taaagaagaa ggtattaaca
     8521 actattcagg tcagaacggg aacacaaatc ccgctgctgt aggagattta ggcggatata
     8581 ccaaatataa aatcaacgat ttatggttga caggtgctgt aaaaatcact cctttggaag
     8641 gattggttat caatgctgat tatacatata atatttatag caagaatgca tcagaggttc
     8701 aacggacatt tacagattat acggctgtag ctggaacaga agctctttat ggttggacaa
     8761 agccaagtta tgcaaattat actacaaatg aagattacta ctatgcattc aatgcatttg
     8821 cagaatattc taaatcattt ttagaaaata cgcataactt taagattatg gccggttata
     8881 accaagaaaa gaaatccaac aaaaaatata atgcaaaacg taccaatctg attgttgaag
     8941 atattcctga cttggatttg gcgacaggtg aacaaagcat gtcttcagaa gatacatatt
     9001 gggcaattaa tggtttcttc ttccgcttca attacaatta caaacaacgt tatctactcg
     9061 aagttaacgg ccgttatgac ggttcatcca agtttgcaaa agatcatcgt tatgcattct
     9121 tcccatctgt ttccgcagca tggcgtatct cagaagaaaa tttctggcag ccgttaaaag
     9181 gttggtggaa tgatatgaaa atccgtggtt cttatggttc attgggaaat caggtaatgg
     9241 atgatctagg taatttccca tatttagcaa catatgggac gaattcttcc tacaattatt
     9301 tgattaacgg atccaaacct gttattgtaa aagcaccggg gcttgtcgct cctgatttta
     9361 cttgggaaac agtcactcaa atggacttcg gttttgatgc ttcatttctg aataatcgac
     9421 tgacgggaac atttgactgg tatcgtagaa atacaaaaga catgttggta gccggagcaa
     9481 ctttacctgc aacattgggc gccagtgttc ctaaaagtaa ctctgctgac atgaagacca
     9541 taggctggga actttcttta ggatggaatg atcgattaga aaatggattt tcttactggg
     9601 taaaaggtgt tttgtctgac tatcaggcga ctatcaccaa atatgccgga aatgacgcag
     9661 gtttctattc acaaagtgat gatgatggta aatattatgt aggacaaaag attggtgaga
     9721 tttggggata tcactcaaac ggccttttcc aatcagacga tgaagctgca acaatagacc
     9781 aaagcgaact ttatgctgga aaatggggtg cgggtgatgt aaaatacgaa gacttagata
     9841 atgatggtaa aatcacaaaa ggggaagaaa caatctataa cccgggtgat aagagcatca
     9901 taggtaataa aacacctcgt tatcaatttg gtattaccgt tggatttgat tataagaact
     9961 tcgatttcga gatgttttgg caaggaacag gaaaacgtga ctatatgttg agtggcgctc
    10021 agttctgggg attcaccagc caatgggatg ttccatatac tccggccctt gattattgga
    10081 cagaaacaaa tacagatgct tattttccaa gaccaggatg gcaaaatggc ggtaacagag
    10141 tcacaagtga ccgttattta caaagtgcag cttacgggcg tttgaagaat ttgacggtag
    10201 gttacacaat tccgaagaat ctaacgacaa agtggggcat ttctcgtttg agattatatg
    10261 tgacaggaga aaacctactc actatcactc ctctgaacga tgccttcgat cccgaaacat
    10321 tgggaggaat gacatacccg attaatcgaa aagttgcaat tggattaaat ttaacactgt
    10381 aaaaaacgaa agatgacaat gaaaactaaa catatcttat taggattaag tcttggattg
    10441 ttaggaggat ttacggcttg tgacgtgaca gacctcaatc caaaagacag cattaccgac
    10501 aatagctact ggaatacagt tagcgatttg gaaaattatg ccaaaggctt ttacatgaac
    10561 ctgacaggaa aaggtttaag ggcagatgga agtgaaaatt tggatgattt aaatactctt
    10621 gatgaaagaa gtgacaatcg tctggtcgct tctcccgacc aatggttgtt caacgaatgg
    10681 gttatacctt ctgaagcaaa tttcgattca aaatggtatt ggaacaatat tcgtaatcta
    10741 aactatttta tgactcgtta ccaacgggta aatgcgacag aatctgaagt aaatccggtt
    10801 gttgccgtaa ttcgcttttt ccgggctttc gattatttcg ataaaatcaa gacatttgga
    10861 gatgttcctt ggtatgaaaa ggatttgaca actgccgata ttgacgaatt gtataaagca
    10921 cgtgacgacc gtgactttgt actagggaaa attatcgaag atctggaatt tgcaattgaa
    10981 tggttaccgg aaaaaagtgc agcagaggta ggtgctttac ataaagatgc cgctcgtaca
    11041 tttttagccc gtgtttgcct acattatgga acatataaaa agtatcataa tgtttcgaca
    11101 tcacctacat ctcaggaatt attacaaaaa gcggcgactc ttgccaaaga agtgatggat
    11161 agtggtcttt acgatatcgt acaaggctcg gatgccggag caaaccagtc tgcttttgcc
    11221 gattatccct tgtattatgc aaaccagttt acacaagagg atttaacgac taataaagaa
    11281 tgtattttag cacgtgtttt cgaagcagac gtattgactc ataatctcgc tcgtggtgga
    11341 ggagtcggcc tttctaaaga ttttgcagaa tcattccttt gcaaggacgg tttgcctatt
    11401 gcaaacagta gtgaatacaa gggagatgaa acactggatg atgaaatggc aaaccgcgat
    11461 cctcgtatgt atcagattat agacagtaaa tatcgtccat atacggtcaa aagcaatggt
    11521 atgcgtgtag taaattccgg tattgatgat aaaaaggaat ttagtccgtc tgaagaacca
    11581 ggaacaaata tccattcagc tccgggatta accgggactg ccacaggata ctcacctatc
    11641 aaactggtgt cagcaagcca gagccaacaa gatgcagtga aaacatcttc ttacgactgg
    11701 tttgttttcc gttacgcaga aatcctgctg atctacgctg aagccaaatg cgaattaggt
    11761 gaatgcacac aggctgtttt ggatgagacg attaataaat tgcgcgaccg tgttgagatg
    11821 aaacatttaa cagtatctcc agtagccgat ctgaatccgg ttgattatgg gtattctata
    11881 actccgttgt tatatgaaat ccgccgtgaa cgtcgtattg agttggcttt ggaaggtttc
    11941 cgttatgatg atatcatgcg ttggaatgcg atgaaactat tcgaaaatcc taaaacatat
    12001 ctaggcatgc gtgttacaga taaagtaaaa gcgttatacc aacctgaagt atttgaagga
    12061 tcaacagccc gtgatttaat cgaatataat ggtaaaactt atatccgcat gtattctggt
    12121 aaaagtttga acgaagccgg ccgtaaatgg acaggaaacg acaagcgtct gtactatcct
    12181 atcccaacaa gtcagattac attgtctgca agccatggtt ctcttctaaa acaaaatccg
    12241 ggttgggaat aaatctcata caagagggaa ggttagcctt ccctctttat ttccctcaat
    12301 aaaatataat gagaatatat tacttatctt attgtctgct ggctaacagg acgtttatat
    12361 tacaatctta tagaatatat agagagttac acacatcata aatgttccga aatcaggcat
    12421 gtatacagta ggtgttcaaa acgggatttt atatgaacaa gaaagactta atattaaata
    12481 ttcttttatt tattagtcaa ataatagtct tttattattt cttctgctat ttattccctt
    12541 ttaaggaaca gctacaaatg tttcaattta catcacagta cctaactgaa acactgaagc
    12601 aggctggtgg tgtcgctatt tatatatcgg aatttctctc tcaattctat gtggtatttt
    12661 ggacaggacc tatcatttct gctctacttt taactttagt ggctttatta tcatcattaa
    12721 tactgaaaaa gattaactca cgaaacgatt tacctcttat tttcctgtta ccctggctat
    12781 ctttactaat tattagttta gactatgatt attatgaaca aggaactatt gcttatttat
    12841 ttttattgct ttttctatgg ctatatacaa acataaaaac acgaataaaa tttatttatg
    12901 gcatttgcat cattcctatt ttatatggaa tagcaggtcc tatcgtacat ttatttgcta
    12961 tatcggcatt gttctttgag tttttaacca atggaaagaa aaaatatatt agtattattt
    13021 atttgttgat tgccgcactt tcagcaattg caggtactta cttaggatat agtagaaatt
    13081 taactttagc gtttttacca gaggcttatt gtaatccact acaaacagta tccgggatat
    13141 attatgcatg gtatgcatta cctatgacaa tgcttctggt tgcttatttg aaacgataca
    13201 aagaacccgt ttctctaaaa gggaaatgta tatgggaagg ggcacaatgg gcaatcatgt
    13261 ttctattggt ctatcaagga atctttcatt ttgggaaatt ggatgcacag cattccatga
    13321 agcaggacta tttgctccgg acggaacagt gggaccttgt tatcagtgaa tttaaccatg
    13381 atgtattgtc taaacgccga atgtgcggtt taaacttagc tttggcacat aaaggccagc
    13441 tttcagagag attgttagat tatcctcaac acggtattga aaccttgatg ctacattggg
    13501 atcagtcgat ctatacagca caactgcata gtgatctgta ttattgtatg ggaataataa
    13561 gcgcagcaca aaaattcgct tttgaagcgt ttgtcagttc tcgttcttcc ggtaatccgc
    13621 ggatgttgaa aaggctgata gagacaaatc tgataacagg gtcctatccg attgcggata
    13681 aatatattca attgttggaa aagacttggt tctataagga ttgggctact gctcaccgtc
    13741 gatttcttta caatgataaa gcagtcgagg aagataaaat tttaggaatg aaacgtcgct
    13801 gttggaaggc cgaagcctct gctgcaaaac tatatacaga tcctgtcagt tcattaataa
    13861 acttgctccc ggcttgtccg gataataaag caggattagc atatttgact tcgtttttac
    13921 tgttgaacaa agatattgaa acttataaaa ccttgcagga gagcttgtac cgttctcccg
    13981 cctggcgcga tatgacggaa tgccagcagg aggcaatcgt gatttgcagt cccaatgatc
    14041 cgcacttctg gttagagcat ggggtgagca tcaaagtaag gaacagagcg atcgctttta
    14101 tgcagaaagt gcaagatatt tcccgttcgg ggcagaatcc tgcggtcgct ttggcttccg
    14161 agtatgacaa aacgtattgg tactattata tgtttaatat gatggacaaa tgaaacaatt
    14221 gcttttttgc atattccttt tgttgttgga aggatgttct tccaaccagc cacctgccgt
    14281 ctccgggcag atagatgaac tgccgaccat ctatccggat tatattgacg taaccatacc
    14341 gcaatcgatc gcacctttga attttgccgt gcaaacggaa gggaaagcat gcgcggtatt
    14401 tacaaccgaa ggatatgcat ttaccgttta cgcctccaac ggagcctttt ccattcccga
    14461 tacagactgg gaaaagttat tgactgcggc aaaagggaaa caggtagagg tatctgtcct
    14521 gacagaagaa aaagggaaat ggaatgcctt tcttccgttt catatccggg tttccgaaga
    14581 cccgatcgat ccgtatatcg cttaccgcct gatcgatccc ggttaccagc tatggaacga
    14641 gatgggaatc tatcaacgcg aattatcctc tttcgatcag gaaccgattc tggaaaaccg
    14701 cctgacggat aataattgca tgaactgcca ttcgttttgc atgcaggacc cggacaaaat
    14761 gctgttccat gtccgtgcaa agtatggctg taccgtgttt gtggatggcg accggataga
    14821 aacgctcgat a
//
