LOCUS       gnlProkkaCJGKLLAI_186  12530 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CJGKLLAI_186.
ACCESSION   gnlProkkaCJGKLLAI_186
VERSION     gnlProkkaCJGKLLAI_186
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 06:20:11
            Original ID  :: gnl|Prokka|CJGKLLAI_186
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12530
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12530
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2179:2530]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2180..2530
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12530
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12530
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             51..446
                     /locus_tag="ctg186_1"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             694..2082
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4.1e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg186_2"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMTIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             2180..2530
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg186_3"
                     /sec_met_domain="PqqD_RRE (E-value: 1.7e-11, bitscore:
                     34.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 6e-18, bitscore: 55.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVA"
     CDS             complement(2713..2997)
                     /locus_tag="ctg186_4"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(3034..4101)
                     /locus_tag="ctg186_5"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELTSVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVGKKAAPAPTVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKIPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             complement(4174..5685)
                     /locus_tag="ctg186_6"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPITSINLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPALTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSEDGIEEMET
                     NYEMLEIEEIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCLTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
     CDS             6748..6972
                     /locus_tag="ctg186_7"
                     /transl_table=11
                     /translation="MMEKTKIGLNAGKVWRILNEKGELSMFDLCRELSLTFEDVALAIG
                     WLAREDKIFLRKREGMLFASIENVEFTFG"
     CDS             7177..8721
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 47.5; E-value: 1.6e-14)"
                     /gene_kind="transport"
                     /locus_tag="ctg186_8"
                     /transl_table=11
                     /translation="MSALKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAMMMAVGQFLMFMSASTLDNTE
                     LAHWMMYGGLGFLILGNGCFKPTVSSLVGQLYEPGDRRLDAAYTIFYMGVNVGSFAAPL
                     ICGYLGDTGDPHDFKWGFLAAGIMTLFTVVLFETQKNKYLFSPSGEPIGIIPDAKREKK
                     EDKAEHISHPKMDKRTKLRNTLVITILTVALIAFFNYAFEGDWVSIGIFTACIVFPVLI
                     LLDGSLTKIERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTNRDILGWEMPASW
                     FQSFNPLFVVVLAYIMPGVWSFLNKRKMEPASPTKQAIGLLLLSLGYLFICFGVKDAIP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEAGKVKSIFGYQIATMYDFFMVFVVMSGVASLILFLLSKKLQKMMHGVE"
     CDS             8763..9299
                     /locus_tag="ctg186_9"
                     /transl_table=11
                     /translation="MDTIQIKDKQFTVSIKEQDIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGVTSSGVIKEVIGLNEDIAGRTVVIVEDI
                     VDTGLTMQRLLDTLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             9367..9936
                     /locus_tag="ctg186_10"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMVDLDVPEEELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTAPLIDWYKNE
                     KKYQHINGLGTMEGIFAEICEAVDKL"
     CDS             10052..11218
                     /locus_tag="ctg186_11"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKGRSFGKDGADKVIEVPCGTVVYNAET
                     GEYLCDVTEDGQEVILLKGGRGGQGNWHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSSISAAKPKIADYPFTTLEPNLGIVSYHGGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     VTKSDMLDQELMDEIEPTLPEGIPHVFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEDIVYEYDDNVDDDDDDIDYEYEEEDWEEK"
     CDS             11215..12027
                     /locus_tag="ctg186_12"
                     /transl_table=11
                     /translation="MISLTKNNELKGYKSLDVYPEVAHFVTTRHEGISTGAYGSFNCSP
                     YTNDSCMNVNRNQSWLFQCMNHQIKELFIPEQSHGCASLIINESFFKESLEMRRLLLRG
                     MDALITNVPGYCVCVTTADCVSVLLYDKKQHVVAAVHAGWKGTVKHIVSHVMDHLNQKF
                     GTQGEDVVACIGPSISLESFEVGDEVYDAFKESGFDMSLISMKKKETGKYHIDLWEANR
                     IELLNAGVPAEQIEVAGICTYIHHDEFFSARRLGIDSGRILSGIMIRK"
ORIGIN
        1 tcagattttt ggagaaattg attattaacg ctaattcaaa ataactaaaa atgtacttat
       61 tattcgttat cttaatggtt attgcagcct tgttgatgtg tttcatcgtg ctgattcaga
      121 actcaaaagg aggcggactt gcttctggtt tctcttcatc taacgccatc atgggcgtgc
      181 gcaagactac agactttctg gaaaaagcaa catggggcct ggccatcttt atggttgtaa
      241 tgagcattgc tactgcttat gtagttcctc gctctgctgt tgctaaagac gcagtgttgg
      301 aacaggcaca gaaagaacaa cagactaacc cgtataactt acccgcaggt acggctgcgc
      361 cgcaaactga agctcctgct accaatgcac ctgctacaga aactccggca ccggctactg
      421 aaactcctgc tcctgcagca gagtaattca ctccgtcgtc aagtaagact ttggggtaaa
      481 accattaatg ggaaggtgca gacggatgct gcatttcttt gatatttaag tgcggattac
      541 gcagattaca cggattttca atgttccgcg tggtcagtgt aatccgcact taactttttc
      601 ttgtaaaaac aatctctttg tgatagaaac aaacgagatt taactacctt tgttggctgt
      661 ataagattat taactacttt tttaaatata acaatgacag aacatttgaa acagaaattg
      721 aatgactccg ccgtactccg atggagtgtt ctagcattgg tcgcatttac tatgctatgc
      781 ggctatttcc tcaccgacgt aatgtctcct ctaaaaccca tgcttgagaa agaactacta
      841 tgggacagtc ttgattatgg tttcttcaca agtgcttacg ggtggtttaa tgtattccta
      901 ttgatgctga tcttcggtgg tatcattttg gataagatgg gagttcgttt caccggaatg
      961 ggggcttgct tattgatggt gtttggttgt ggattgaaat actatgcgat ttctactact
     1021 tttccggaag gtgccatgct cttcggattc aaaacacagg tgacgttggc tgcattggga
     1081 tatgctatct ttggtgtagg tgtggagatt gctggtatca ctgtttccaa gattatagtg
     1141 aaatggttca agggcaagga aatggcattg gctatgggac ttgaaatggc tacggcacgt
     1201 atcggaacaa ctctggcgat ggtattgaca gttcctttgg cagacttttt cggatctacg
     1261 gatgagagtg gcacattcca tacaaatatt cctgctccga ttttgttttg tctgattatg
     1321 ttgtgcgtgg gtacgattgc ttttttcctt tatactttct atgataagaa gttggatgct
     1381 tctttggatg cagagggatt ggaaccggaa gaaccgttcc gtatgaaaga tattgtgtat
     1441 attattacca ataaaggatt ctggttgatt gcattactat gtgtattgtt ctactcggct
     1501 gtattcccct ttatcaagta tgctgccgac ttgatggtgc agaaatataa cgtagatccg
     1561 aagttggcgg gaacgattcc cggattgttg ccgattggtg cgattatcct gactccgttg
     1621 ttcggttcgc tttatgaccg tatcggtaag ggagccacat tgatgataat cggatcagtg
     1681 atgcttattt ttgtgcatac gatgtttgct ctgcctatac tgaatatatg gtggtttgct
     1741 actatcatca tgattatatt gggatttgcc ttctcgttgg tgccttcagc tatgtggccg
     1801 tctgttccga agattattcc ggaaaaacag ttgggtaccg catacgcatt gattttctgg
     1861 gtacagaact ggggattgat gggtgttcct ttgttgatcg gatgggtgtt gaatacttat
     1921 tgcaaaggtc cggtagtaga cggtgcacag acttatgact acacgttgcc gatgactatt
     1981 tttgctctct ttggtgtact tgctctgatt gtggctttga tgttgaaggc agagaacaag
     2041 aagaagggat acggtctgga agaggcgaat atccaaaagt aactgggaaa ttcaatacct
     2101 aaagtaacaa aggaattttg tatcaaggtg taaacaaaag ggtatcagta tgaatactct
     2161 gaaataaaaa ataagaagta tggctgccaa agagaaaatc aacctgttag aggtcattcc
     2221 ctgtcgcagt gaacatatta cagcagaaag ggaaggggag acaattgtgc tctcctttcc
     2281 ccgttttaaa tatccgtgga tgcaacgctt ccttgtgccg aaaggaatgt cgaaagaact
     2341 tcatgtgaaa ttggaagaac acggtacggc tgtatgggaa ctgatagatg gaaaacgcaa
     2401 tgttcgtgag attatagaaa aactcgcaga ccattttcaa aatgaagagg gctacgagtc
     2461 gcgtgtatcg gcttatcttt ctcaaatgca gaaagatgga tttataaaac tggtgatacc
     2521 agtcgcataa ataggaattt atatttcacc acagaggaca cggaggacac agagttcttc
     2581 tctctctttc cgcaagtaaa acagagcgat aaatacgatt ctcaatacgt gagactctgt
     2641 gttactctat agtgaataaa aaagattaaa cctctgtgtc ctccgtgtcc tctgtggtga
     2701 atttattatt atttatttga taaatacagc ccaaagtatg acggcaattg ctatcaggac
     2761 tcccatgata ataagcgttc cccaaacaaa ataattgctg tctttctctt tctttttctc
     2821 cgagtcgtgg atgatacgtt ccatttcttc gggagtggta ttgggtagtg gataaggttc
     2881 gtttgcacgg tttaaatgct tcaacttgtc gttagcacgt tcacgacgta ggcgggaagc
     2941 ttcccgtccc tcttttattc ggcgtatcat gtcgaatgca tgtccttcac caaccatatt
     3001 ctttgttttt tagaagttca ctttctcgtt tttctatttc ccttcttctc tgtccacttt
     3061 gagcaatcct cccgtattcg gatcaaaata aactttgatg gtagaattct tgttgaacaa
     3121 aaccggagcc agatattcta tcacaccaaa ttgagtaata ggaagttcac cttcgtaaag
     3181 tttctttttg ccgtcggtca atgtaaccat agcttgtccg ggtacgttgt aggcgattcc
     3241 atccaaatct ttcttcttct taccatcttc ctgtggtatc ttgaccgatt tcaggtcttt
     3301 cagactgata taaaacggag ttcctgccaa atcattgttg gcaactacac ctaacttctt
     3361 cgagaagcgg aaagcaactt cattgttgaa ttccttgtca ggggtaaggc ggacagtgaa
     3421 tgttctctct tccttgttgc aggtgccgga gaacatttgc gtcatggctt cttcctgtgc
     3481 attcagattg tcgagcataa tcttaagctg tgctccgtct gaaggcatat tgtcagcctg
     3541 tccgcgcaat aaggcatttt tgctttcgcg gatgttatag atttctttag ccaccagttc
     3601 ggccatcttg gcggtagagc tagccatcag aatctcttcg gtcaggaatt cacgaggatt
     3661 tgctttcttt tggaggactg tgggagcggg agcggctttt ttgcctacac tgctgttgct
     3721 gtaaggaaca ttgatcgttt tcacaatgcc atcctctgtc agttccatga gcggtgctac
     3781 tgtcttatcc ttcaatttta cgaaatacgt cgtttcgctg ttgggcacac ctacggattt
     3841 cacttttacg ctagtcagtt cccagtactc ttcagggtcg gcggagacgt tggtcagtcg
     3901 caggtaacga tcagcatatt tgctgaattc tcccggagta tagttgactt tgttggcttt
     3961 tatttcaagt tctatttggg ttttgggaag actgtaaacc actccatagt cttttcctcg
     4021 ggtaacccct gtcagtactt cggtttgtgc ataggcggac gttgtcataa gtagtcctgc
     4081 tgctataatc aactttttca tattcggttc tttttaactg gttttgaaaa caaagttaat
     4141 gaagttattg aaaaaactgt aagttcttaa cttttattcg cttacaagtc gccatgctgt
     4201 cggcagacag gtgataatat cgcttgcgat cattccgatc attccttgct tcttttgagc
     4261 gacatcgccc gccaatccgt gaatgtaagt gccgatttta gcggcttctt cggtgggata
     4321 accttgggca agcagcgcca ggattactcc ggtcagtacg tcaccgctac ctccggttgc
     4381 cattcccgga tttccggttg ggttgaagaa acatttacct tcgggggtga tgatggcgga
     4441 gtaggctcct tttaaaataa tgtggacatg ggcggcacgg gccagttcgc aagccttcat
     4501 cagacgttcg taagagtcct ggcatttgcc ggtcagacgt tccagttctt ttggatgcgg
     4561 ggtgaggatg gaacccttcg gcagatgggt aagggcatga cggtggttgg cgaggatatt
     4621 aagagcgtcg gcatctacta caacaggagt caggcagtgt tccagttgtt ccaataaggc
     4681 agcttccgtt tcctcgtttc gtcccagtcc cgggccgatg ccgactgctt gatagtcgtc
     4741 cgtgtcggta ggtacggcaa aacaggtttc gttgatgtcg gtttctacga ttgcttcggg
     4801 tatggaggtc tgcaagatgt cgttgttgca cattggcgca tgaacagtca gcagccctac
     4861 tcccgaacgg aggcaggcgc gggcagcgag aacagaggct cctgccattc cttttgaacc
     4921 ggcaatcaat agtgcatggc cgaagttccc cttgtgggca aactgtttgc gtggcttgat
     4981 gagtgaacgg atttcttcta tttccaacat ttcgtagtta gtctccatct cttcaatacc
     5041 gtcttcgctt aattggatat ccagcacttc ccattctccg acaaattcag tgttctctgc
     5101 gaaaagaaag gcgagcttcg gcagttgcag actgaaagtt acgtcggcgc ggataatatt
     5161 agcttttacg ttgaatgtat tttcttctcc catcagtccg gaaggaatgt cgatggctac
     5221 taccatagca ggggaggaat tgatgtattt cactacggca gcgaatccgc cgcttaacgg
     5281 tttgttcagg cctgaaccga ataatccgtc gattaccaga tggtcgggcg tcagggcggg
     5341 aggtacgaat tgggtactga tttcgtggaa ttttacttct tccatcattt ctaccagttc
     5401 tttattggtc tggcagtcgg gtgaaagttc tcctttcgtg ttgaagagaa atacctcgat
     5461 tttatatcct ttttcagcca tcatgcgggc tacggcgaga gcgtctccac cattattccc
     5521 cggtccggca aagatagtga ccggcgtttc cgtattccat ctgtctgtga tggcttttgt
     5581 taatacggtt gctgcacgtt ccatcagatt gattgatgta ataggttcgt tctcaatggt
     5641 ataagcgtcc aatttcttga tactgctgct tggaaatatt ttcattgcga tgttctttta
     5701 gttttcggat tacaaatgta catgattctt ctgacttttc ccgtttgttg tgggaagaaa
     5761 accataattg caacttttaa ttcatcatta gttctatctt ttggtcaaag aaatatctgc
     5821 ttttaaacta ttaagtgtta gaataactcc gctaaaaaat aattcaatgc tgcaccatta
     5881 tgaacttact tttatttctc cctgaaaaag atttcttcat ttcatttctc atattctcat
     5941 tgtttttcga taaacgaaag ataatcaaat agatatctta tgagaaacac tttttcaaaa
     6001 cggtatttct cataagttct cccatgtttt ggctcaaaag ccaccttatt ctcatcgtat
     6061 ttcagggtat ttctcatagt caaaagccat tctttcttcc ttttttcttt cagcctgcct
     6121 tatttttatc aggaaatgaa gctactattt agataaaata gtggcttttt gcttggagat
     6181 gctcgttgtt ctcgattgtc ccatatattg tgggaaagta ttctcgtata ttgaaggaaa
     6241 actttcccac aaaataaggg aatactttcc caagccttag ggaatctttt cccacaatat
     6301 gtgggactaa gacactgtgt atggaagcaa gcaaaaggaa tatatagttc tatttattca
     6361 atgtcagctt ccggcacgct acactatgag aaatgaagca aaatccgggt tattttgcga
     6421 agaaactatg agaaatgcct gttttaaaat catttctcat agtctatctt attagtttac
     6481 tgccacttgt gccttattta tgagaatatg agaaatgaaa atgaaaaatc tttttctgta
     6541 gaggggcgga tggaaattgt gtttagttta tctccatacc ttcttaaaca aatttttaat
     6601 gcggttccct tgattaagcc tttgattatt tgccgtttcc gataaaaatg ttatctttgg
     6661 agatagataa tgtgcatcac attaatttcc tgtgctcaca atgaattaga atctaaataa
     6721 cggattgttt aatcttctaa agtttgcatg atggaaaaga caaaaattgg cttgaatgcc
     6781 gggaaagtat ggcgcatctt aaatgaaaaa ggtgaacttt caatgttcga tttgtgccgt
     6841 gaattaagtt tgacgtttga agacgtagct cttgctattg gttggctggc ccgagaagac
     6901 aaaatctttt tgaggaaaag agaaggaatg ctttttgcca gtatcgaaaa tgtcgaattt
     6961 acttttggct aaggtggtag ctaacctata tttaagatgg atctccactt tgttatttac
     7021 acagctaaaa aaataatgaa gtggatcagt aggatttttt atgcccattt ttattattcc
     7081 ccctatattc ccgtttgata agaactttct ttttttgaag catttaatct atttttcgta
     7141 cctttgcacc ccataaacta ctaaacacat aaattcatga gtgcattgaa agggcatccg
     7201 aaaggccttt atctgatttt cgcgacaagc acggcagaac gtttcagtta ctacggtatg
     7261 cgtgcgatct ttattctttt cctgacgcag gcattattgt ttgacaaaga agcggcagca
     7321 tccatttacg gtagctatac cgggttagtc tatttaactc ctttgattgg cggatacatt
     7381 gccgataaat attggggaat ccgtcgctct gtgttttggg gagcaatgat gatggcagtc
     7441 ggacaattcc tgatgtttat gagtgcctct actttagata atacggaact tgctcactgg
     7501 atgatgtatg gcggactcgg attcctgatc ttgggaaatg gttgtttcaa acctaccgtt
     7561 tcttctcttg taggtcaact ctacgaaccg ggagacagac ggctggatgc tgcatatacc
     7621 atcttctata tgggagtgaa tgtaggttct tttgccgccc ctttgatttg tggttatctg
     7681 ggcgataccg gtgacccgca cgattttaaa tggggatttc ttgcagccgg aatcatgaca
     7741 ctgttcactg ttgtactttt tgaaactcaa aagaataaat atcttttctc tccttccgga
     7801 gagccaatcg gtattatccc cgatgccaaa cgtgaaaaga aagaggataa agccgagcat
     7861 atctcacacc cgaagatgga taagcgtacc aagttgcgta atacccttgt aatcactatt
     7921 cttacagttg ctttaatagc cttctttaat tacgcttttg agggtgactg ggtgagcatc
     7981 ggtattttta ccgcctgcat tgttttccct gttctcatcc tattggatgg ttcattaacc
     8041 aagatcgaac gtagtcgtat tttcgttatc tatatagtag ctttctttgt cattttcttc
     8101 tgggcggctt acgaacaggc aggagcctct ttaactctct ttgcctccga acaaaccaat
     8161 cgtgatattt taggttggga aatgccggct tcgtggtttc aatccttcaa tcctctgttt
     8221 gttgttgttc tggcatatat aatgccgggt gtgtggagct tcctcaacaa acgaaagatg
     8281 gaacctgctt ctcctaccaa acaagcgatt ggcttgttac ttctttcttt aggttatctt
     8341 ttcatctgtt tcggagtgaa agatgctatc cccggagtga aggtaagtat gatttggctg
     8401 acaggacttt attttattca tacaatgggt gaaatagcct tgtcacctat cggactttca
     8461 atggtaaata agttgagtcc gctacgtttc gcctctttga tgatgggaat ctggtatctg
     8521 tctactgcca cagccaataa atttgcaggc atgttgagtg gactttatcc ggaagccgga
     8581 aaagtgaaat caatctttgg ttatcagatt gctaccatgt acgatttctt tatggtattc
     8641 gttgtcatgt ccggtgttgc ttcattgatt ctgttccttc tctcgaagaa attacagaag
     8701 atgatgcacg gggtagaata aaaaatcgta tttttgcaag gttatttttt aaattaccgg
     8761 ttatggatac cattcagata aaagacaaac agttcactgt ttctattaag gaacaggata
     8821 ttcagaaaga agtgattcgc gtagcgaacg aaatcaaccg cgacttggca ggtaagaatc
     8881 cgctcttcct tagtgtgttg aacggttcat ttatgtttac tgccgacttg ttgaagcaca
     8941 tcaccatccc ttgcgagatt tcgtttgtga aactggcttc ttatcaggga gtgacttcct
     9001 cgggagtgat taaggaagtg atcggactga atgaagacat tgccggacgt acagtagtta
     9061 ttgtagaaga tattgtggat accgggctaa ccatgcaacg cctgttggat acattgggta
     9121 cacgcaaccc tgaagcaatc catattgctt ctctgctagt gaagcctgaa aaactcaagg
     9181 tcaatctgaa catcgaatac gtagcaatgg aaatcccgaa cgactttatc gtaggttacg
     9241 gactggatta tgatggtttc ggacgcaact atcccgatat ttatacagta gtagattaaa
     9301 cagttaatat taaataggta ccagtttaaa tggtaaatag taaatcgtta aattgtaaat
     9361 aacaaaatgt tgaacatcgt aattttcggt gctccgggtt caggaaaagg aacacagagc
     9421 gaacgtattg tagaaaagta tggaatcaat cacatctcaa caggagatgt attgcgtgct
     9481 gaaatcaaga atggcacaga attgggtaaa actgctaaag gttacatcga ccaaggtcaa
     9541 ttgattcctg atgaattaat gattgatatt ctggcaagcg tattcgacag cttcaaagat
     9601 agcaaaggtg taattttcga cggtttccca agaacaattg cacaagctga agcattaaag
     9661 aaaatgttgg cagaaagagg acaggatgtt tctgtaatgg ttgacctgga tgttccggaa
     9721 gaagaactga tggtacgtct gattaaacgt ggtaaggatt ccggtcgtgc tgatgataac
     9781 gaagagacaa tcaaaaaacg tctgcacgta tatcattcac agactgcccc actgatcgac
     9841 tggtacaaga acgaaaagaa ataccaacac atcaacggct tgggtactat ggaaggtatc
     9901 tttgctgaaa tctgcgaagc agtagataaa ttgtaattta gtaatcttac taattatcaa
     9961 tacactatta taaatgaata agtcagtcag tagccggagt attctactta attactctaa
    10021 ctactgacta ctttaactac ttaaaaagaa tatggctgaa tcgaattttg ttgattacgt
    10081 aaagatatac tgtcgctcgg gtaagggcgg aagaggctct acgcacatga ggcgcgagaa
    10141 atattgtcct aacggaggtc ccgatggggg cgatggtgga agaggaggtc atatcatctt
    10201 gcgcggtaac cgtaattact ggacattgtt gcacttgaag tatgaccgtc acgcaatggc
    10261 cggtcatggt gaatcgggga gtaaaggacg tagtttcgga aaagacggtg cggataaagt
    10321 aatagaagtg ccctgcggaa cggtcgttta taatgccgag acaggggaat atctttgtga
    10381 cgtaacagaa gacggacagg aagtgatctt gctcaaaggc ggtcgtggtg gtcagggtaa
    10441 ctggcatttc aagacggcaa cccgtcaggc tccgcgtttt gcacagccgg gagaaccgat
    10501 gcaggaaatg accgttatca tggagctgaa actgcttgcc gatgttggtc tggtaggttt
    10561 cccgaatgcg ggtaagtcaa ctttgctttc ttctatttcg gctgccaaac cgaaaattgc
    10621 tgattatccg tttactacgc tcgaacccaa tttgggtatc gtttcctatc acggtggaaa
    10681 gtctttcgtg atggcggaca taccgggtat tatcgaggga gccagtcagg gtaaaggctt
    10741 gggactgcgt ttcctgcgtc atatcgagcg caattcatta ctgctgttta tggttccggc
    10801 agacagtgac gacattcgta aggaatacga agtcttgctg aacgaactgc gtactttcaa
    10861 tcctgaaatg ttggacaagc aacgtgtgtt ggctgtcacc aagagcgata tgctcgatca
    10921 ggaattgatg gacgaaatag aacctacatt gccggaaggc attccccacg tattcatatc
    10981 ttctgtttcc ggtttgggta tctcggtgtt gaaagacatt ctttgggaag aactgaataa
    11041 ggaaagcaat aagatagagg acatcgttca ccgtccgaag gacgtaaccc gtctgcaaca
    11101 ggagctcaaa gacatgggcg aagatgaaga catcgtttat gaatatgatg acaatgttga
    11161 tgatgatgac gatgatatcg actatgaata cgaggaagaa gattgggaag aaaaatgatt
    11221 tcacttacaa aaaataatga gttgaaggga tataagtcac tggatgtata tcccgaggta
    11281 gctcatttcg taacaacgcg tcacgaaggt ataagcaccg gagcttacgg ctctttcaac
    11341 tgttcgcctt ataccaacga ctcatgtatg aacgtcaatc gcaatcagag ctggttgttt
    11401 cagtgcatga atcatcagat aaaggagttg tttattcctg aacagagcca tggttgtgcc
    11461 agtctgatta tcaatgaatc attttttaaa gagtcattag aaatgagacg gctacttttg
    11521 cgaggaatgg atgccttgat aactaatgtg ccggggtatt gcgtttgcgt cacgacggcg
    11581 gattgtgttt ctgtattgct gtacgacaaa aaacaacacg ttgtggctgc cgttcatgcc
    11641 ggatggaaag gaactgtgaa gcatattgtc agtcatgtga tggatcactt gaatcagaaa
    11701 ttcgggacgc aaggcgaaga tgtggtagct tgcatcgggc cgagcatttc gctcgaatca
    11761 tttgaagtag gtgatgaggt gtatgatgct tttaaagaaa gcggtttcga tatgtctctt
    11821 atttctatga agaagaagga gacgggcaaa tatcatattg atttgtggga agccaaccgg
    11881 attgaattac tgaatgccgg agtgcctgca gaacagatag aagtagctgg catctgtacc
    11941 tatattcatc atgatgaatt cttctccgca cgtagactgg gaatagattc cggtcgtatc
    12001 ttgtcgggaa taatgattag aaagtaataa ttggtgtccg taattgcagg acgctgatga
    12061 ttggtttatg ataagttatg tttgaaataa aagtatctaa agaaataaaa gacgcatgcc
    12121 cggtttttgc cggagccgcc gtgtatgctg cagtgaagaa tactgcttac aacgaagggc
    12181 tttggcagga aatcaacgct tttaccaggc aactgacttc cactacacag atggaagaca
    12241 tcaaacatca acccgttatc tttgctaccc gtgaggctta taaacgttgt ggcaaagacc
    12301 ccggacgtta tcgcccgtca gccgaagctc tacgccgccg cctgatgcgt ggaatcccgc
    12361 tatatcagat tgatacactg gtagacctga ttaacctcgt gtctcttcgt acgggacatt
    12421 ctattggtgg tttcgatgcg gataaaatac aaggtacgca ccttgaactc ggtatcggca
    12481 aagctggaga accgtttgaa ggtatcggac gcggggtgtt gaatatcgaa
//
