LOCUS       c00159_gnlPro..        13472 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CJGKLLAI_159.
ACCESSION   c00159_gnlPro..
VERSION     c00159_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 12:01:00
            Original ID  :: gnl|Prokka|CJGKLLAI_159
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13472
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13472
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:3472](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..3472
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..13472
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13472
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             2..3472
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg159_1"
                     /sec_met_domain="PFOR_II (E-value: 8.6e-19, bitscore: 58.0,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1.6e-81, bitscore: 263.5,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 8.8e-32, bitscore: 100.6,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.9e-12, bitscore:
                     37.3, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 3.6e-12, bitscore: 37.3,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 5.5e-09, bitscore: 26.1,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.7e-05, bitscore: 14.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 2.2e-25, bitscore: 78.5,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="AAIYPITPSSTMAEYVDEWAAAGRKNIFGETVLVQEMQSEGGAAG
                     AVHGSLQAGALTTTYTASQGLLLMIPNMYKIAGEFLPCVFHVSARTLASHALCIFGDHQ
                     DVMSARQTGFAMLAEGSVQEVMDLAGVAHLATIKSRVPFMNFFDGFRTSHEIQKIEMLE
                     NDDLAPLIDQEALAEFRARALNPMKPVARGMAENPDHFFQHRESCNNYYEAVPAIVEEY
                     MNEISKITGRKYGLFDYYGAEDAERVIIAMGSVTEAAREAIDYLVANGEKVGMVAVHLY
                     RPFSAKHFLAAVPKTAKTIAVLDRTKEPGANGEPLYLDVKDCFYGAENAPVIVGGRYGL
                     GSKDTTPAQILSVFENLAMPMPKNHFTIGIVDDVTFTSLPQKEEIALGGEGMFEAKFYG
                     LGADGTVGANKNSVKIIGDNTDKHCQAYFSYDSKKSGGFTCSHLRFGDNPIRSTYLVNT
                     PNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIWEGEELAKNLPNKVKKYFAQNNISVYY
                     INATQIALEIGLGNRTNTILQSAFFRITGVIPVEQAVEQMKKFIVKSYGKKGEDVVNKN
                     YAAVDRGGEYKTLAVDPAWANLPDDAKAENNDPAFINEVVRPINAQDGDLLPVSAFKGI
                     EDGTWYQGTAKYEKRGVAAFVPEWNPENCIQCNKCAYVCPHASIRPFVLDAEEQKGAKF
                     EQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADICPGNPKKGGKALTMKHLESQLAQAEN
                     WTYCAENVKTKQHLVDIKANVKNSQFATPLFEFSGACSGCGETPYVKLISQLFGDREMV
                     ANATGCSSIYSGSVPSTPYTTNENGHGPAWANSLFEDFCEFGLGMELANEKMRARLVKV
                     MNEAIAADCTPAEVKELFAEWINNMLDADKTKELAAKIIPVVEANKDKCNHCKQIAELQ
                     QYLVKRSQWIIGGDGASYDIGYGGLDHVIASGKDVNILVLDTEVYSNTGGQSSKATPVG
                     AIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIAMGADQAQTLKAIREAEAYPGPSLIIA
                     YAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWRYNPALEEEGKNPFQLDSKEPNWEDFQ
                     GFLKGEVRYASVMKQYPAEAEELFKAAEENAKWRYNSYKRLARENWGAE"
     CDS             complement(3625..4491)
                     /locus_tag="ctg159_2"
                     /transl_table=11
                     /translation="MRIYKIVGIVLSAMLLLASCAHSDLEEKKIKIAYANWLEGIAMSH
                     LAKVVLEEHGYEVELQNADLAPIFVSMSGKKSDVFLDAWLPITMKDYMDQYGDSIEFLG
                     EVYGEARVGLVVPQYVTIQSISELEANKDRFSSEIVGIDAGAGIMKTTDKAIAAYGLDG
                     YTLMTSSSSTMLASLKKAMDKGEWIVITGWTPHWMFDQFDLKFLDDPKKVYGDLEEIHA
                     IAWKGFSEKDPFAAEFFGNIKLTTEELSSFMTAMKDARMDEEEIARKWRDEHRQLVDSW
                     IPKSENK"
     CDS             complement(4512..5336)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 92.5; E-value: 9e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg159_3"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.3e-29, bitscore:
                     92.5, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIEMAINWMMVHFSTFFDAINAGIGSFIIGFQHVLFGIP
                     FYITILVLAALAWMKAGRGTAIFTALGLLLIYGMGFWEATMQTLALVFSSTCLALIVGV
                     PLGVWTANSPRAEKILRPVLDLMQTMPAFVYLIPAVLFFGLGAVPGVFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATRWQLLYKVQLPLALPTILTGVNQTIMMSLSMVVIA
                     AMIAAGGLGEIVLKGITQMKIGLGFEGGIVVVILAIILDRITQGMAGRKNKN"
     CDS             complement(5333..6559)
                     /locus_tag="ctg159_4"
                     /transl_table=11
                     /translation="MSKIEIKDLYLIFGNEKQKALKMLKKDKSKEEILKDTGCTVGVKD
                     ANLSINEGEFFVIMGLSGSGKSTLLRCINRLIRPTAGQVLVNGVDISKISEKELLQVRR
                     KELAMVFQNFGLLPHRSVLSNIAFGLELQGVKKEEREKKAMESMKLVGLKGYENQMVGE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLALQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEVVQVGTSEEILTEPANDYVARFVENVDRSKIITASSLMID
                     KPLVARLKKEGPEVLIRKMRAKNITVLPVIDADDKLVGEVRLNDLLKLRSRQEKSIETI
                     VRTEVHSVLEDTVLEDILPLMTKSNSPVWVIDETHEFLGTIPLSSLIIEVTGKDKEEIN
                     EIIQNAIDL"
     CDS             complement(6859..7143)
                     /locus_tag="ctg159_5"
                     /transl_table=11
                     /translation="VYQVVREIPVGKVSTYGGIAALLGMPQCSRMVGRALKQVPDDLST
                     PCHRVVNASGRLVPGWTEQKQLLLEEGISFKQNGCVDLKKHLWNYSVPE"
     CDS             7281..8669
                     /locus_tag="ctg159_6"
                     /transl_table=11
                     /translation="MQLYLLYLQIIPTFVPIKSNPIINKTSTAVMKKKTILFASCLFGV
                     FAFSSCEKNLYDESKQPEKEIQVKDLDIPAGFQWKLTQVAAGTVAATTPTMVSFFLDEA
                     CSKEEKIADIPVDTEISSLPLSIPTYVNTLYAQYKTSTNEIKKVAIPVNADRSFSLNIA
                     NDAKSKSNTTRSITRGHDIEDDIQLSKGVIFHPKDGWGTIMFEDQFPSLGDYDFNDFVV
                     NYKVQFQGIKKVDKKYTAQYIQIGLRLKAIGGIFPYSPYLRLKEIDSDEVESIEVYETK
                     NVIPAIDGVDLVPNKHLIIDYSPLIKNLAKPAGSQYYNTEKNALVATSDLPEINILITL
                     KKRKEVKEILEGDEFDLYLKRNDSGTEIHMNGIEPITYQYPFNDKNLLPVYTNGDEEDD
                     NYYFSAGRLIWGLRVPGNAAHAIEKANFLEAYKGFAKWAQSSGKNEQNWYNQGNADKSL
                     LIHN"
     CDS             complement(8750..11545)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 61.6; E-value: 2.7e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg159_7"
                     /sec_met_domain="Peripla_BP_1 (E-value: 7e-20, bitscore:
                     61.6, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRMMGYTKWIAVLLCLLGMTACRQDAPRFRIGVAQCSDDSWRHK
                     MNDEILREAMFYDGVSVEIRSAADDNRKQAEDVHYFIDEGVDLLIISANEAAPMTPIVE
                     EAYQKGIPVILVDRKILSDKYTAYIGADNYEIGRAVGNYIASSLKGKGNVVELTGLGGS
                     TPAMERHQGFMAAISNFPDIKLIDKADAAWEREPAEVEMDSMLRRHPKIDAVYAHNDRI
                     APGAYQAAKKVGREKEMIFVGIDALPGKGNGLEMVLDSVLNATFIYPTNGDKVMQLAMN
                     ILEKKPYPRETVMNTAVVDRTNAHVMQLQTTHISELDQKIETLNGRIGGYLSRVATQQV
                     VMYGGLVILLLVAGLLLVVYKSLRAKNRLNKELSEQKKQLEEQRDKLEEQRDQLIQLSH
                     QLEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADHTLSGDQHRMLMLIQRNVNILL
                     RLVNQILDFRKYENGKMEYTPVQVDVLSSFEGWNESFLAVARKKHIHFSFDNMPDTDYH
                     TLADMEKLERIYFNLLSNAFKFTPENGKITVRLSSLTKEDTRWIRFTIANTGSMISAEH
                     IRSIFDRFYKIDMHHAGSGIGLALVKAFVELHKGTISVESDEKQGTVFTVDLPVQTCET
                     ILAEDSLKSSISAVPLNPASPGSPASSDLNESLVVEEEELEKGYDSSKPSVLVIDDNAD
                     IRSYVRGLLHTDYTVIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQ
                     TCHIPVILLTACSLDEQRIQGYDGGTDSYISKPFSSQLLLARVRNLIDSHRRLKQFFGD
                     GQTLAKEDVCDMDKDFVEKFKALIEAKMGDSNLNVEDLGKDMGLSRVQLYRKIKSLTNY
                     SPNELLRIARLKKAASLLASSDMTVAEIGYEVGFSSPSYFTKCYREQFGESPTDLLKRK
                     G"
     CDS             complement(11969..12856)
                     /locus_tag="ctg159_8"
                     /transl_table=11
                     /translation="MNNIIVGMGEALWDVLPEGKKIGGAPANFAYHVSQFGFDSRVVSA
                     VGKDELGDEILNVFNEKKLKTQIEQVDYPTGTVQVTLDNEGVPCYEIKEGVAWDNIPFT
                     DELKRLALSTRAVCFGSLAQRNEVSRATINRFLDTMPDIDGQLKIFDINLRQDFYTKEV
                     LRESFRRCNILKINDEELVTISRMFGYPGIDLQDKCWILLAKYNLKMLILTCGINGSYV
                     FTPGVVSFQETPRVPVADTVGAGDSFTAAFCASILNGKPVPEAHKLAVEVSAYVCTQSG
                     AMPELPQVLKDKLM"
ORIGIN
        1 agcagctatc taccccatca ctccttcttc gactatggct gagtacgtag acgaatgggc
       61 tgccgcagga cgtaagaaca tcttcggcga aacagtatta gtacaggaaa tgcaatctga
      121 aggtggtgct gccggtgcag ttcacggttc tcttcaggct ggtgcgttga ctactactta
      181 cactgcttcc cagggtcttc tcctgatgat ccctaacatg tacaaaattg ccggtgagtt
      241 cttgccttgc gtattccatg tatctgctcg tacattggct tctcacgcat tgtgtatctt
      301 cggtgaccac caagacgtaa tgtcagctcg tcagactggc tttgctatgt tggctgaagg
      361 ctctgtacag gaagttatgg atttggctgg tgttgctcac ttggctacca tcaaatctcg
      421 cgttccgttc atgaacttct tcgatggttt ccgtacatct cacgaaatcc aaaagattga
      481 aatgttggaa aatgatgatc ttgctccact gatcgaccag gaagctttgg ctgaattccg
      541 tgcccgcgca ctgaacccga tgaaaccggt agctcgtggt atggctgaaa atcctgacca
      601 tttcttccaa catcgtgaat catgcaacaa ctactatgaa gcagttcctg ctatcgtaga
      661 agaatacatg aatgaaattt ctaagatcac aggtcgtaaa tacggtttgt tcgattacta
      721 tggtgcagaa gatgcagaac gcgtaattat cgctatgggt tctgtaacag aagctgcccg
      781 cgaagctatc gactacctgg tagcaaacgg cgaaaaagtg ggtatggttg ccgtacacct
      841 gtatcgtccg ttctctgcta aacacttctt ggctgctgta cctaagactg ctaaaactat
      901 cgcagttctt gaccgtacta aagaaccggg tgctaacggc gaacctcttt accttgacgt
      961 taaagactgc ttctacggtg cagaaaatgc tccggttatc gttggcggtc gctacggttt
     1021 gggttcaaaa gatactactc ctgctcaaat tctttcagta ttcgaaaact tggctatgcc
     1081 aatgccgaag aaccacttca ctatcggtat cgtagacgac gttactttca cttctcttcc
     1141 tcaaaaagaa gaaatcgctt taggcggcga aggtatgttc gaagctaaat tctacggttt
     1201 gggtgctgac ggtacagtag gtgctaacaa gaactctgta aagattatcg gtgacaacac
     1261 tgacaaacac tgccaggctt acttctctta tgactctaag aagtcgggtg gtttcacttg
     1321 ttctcacttg cgtttcggtg acaatccaat ccgttctact tatctggtaa atactccgaa
     1381 cttcgttgct tgtcacgttc aggcttacct gcacatgtac gatgtaactc gtggtttgcg
     1441 taagaacggt tctttcttgc tgaacacaat ctgggaaggt gaagaactgg ctaagaacct
     1501 gcctaacaag gttaagaaat attttgcaca gaacaacatt tctgtatact atatcaacgc
     1561 aacacagatt gcactggaaa ttggtttggg taaccgtacc aacacaatcc ttcaatctgc
     1621 attcttccgt atcacaggcg ttattcctgt agaacaagct gttgagcaga tgaagaaatt
     1681 catcgttaag tcttacggca agaagggtga agacgttgtt aacaagaact atgctgccgt
     1741 tgaccgtggt ggtgaataca agactttggc tgttgatcct gcttgggcta accttccgga
     1801 tgacgcaaaa gctgaaaaca acgatcctgc attcatcaac gaagtagttc gtccgatcaa
     1861 tgcacaagac ggtgacttgt tgccggtatc tgcattcaag ggtatcgaag acggtacttg
     1921 gtatcaaggt actgctaaat acgaaaaacg tggtgtagct gcattcgttc ctgaatggaa
     1981 tccggaaaac tgtatccagt gtaacaagtg tgcatacgtt tgtcctcacg cttctatccg
     2041 tccgttcgta ctcgacgctg aagagcagaa gggtgctaag ttcgaacaac tgaaagctgt
     2101 aggtaaagca ttcgacggta tgacattccg tatccaggtg gacgttctcg actgtctggg
     2161 ttgcggtaac tgtgccgaca tctgtccggg taatccgaag aagggtggca aagcattgac
     2221 aatgaaacac ctcgaaagcc aattggctca agctgaaaac tggacttact gtgctgaaaa
     2281 cgtgaagact aaacaacatc ttgttgatat caaggctaac gtgaagaact cacagttcgc
     2341 tactccgttg tttgagttct ccggcgcttg ctctggttgt ggtgaaactc catacgtgaa
     2401 attgatttct caattgttcg gtgaccgtga aatggttgct aacgctaccg gatgttcttc
     2461 tatctactct ggttctgttc cttctactcc gtatactaca aacgaaaacg gacacggtcc
     2521 tgcttgggct aactcactgt tcgaagactt ctgtgaattc ggtttgggta tggaactggc
     2581 taacgaaaag atgcgtgctc gtctcgtgaa agtgatgaac gaggctattg ctgctgattg
     2641 cactcctgct gaagtaaaag aactgttcgc tgaatggatc aacaatatgc tggatgcgga
     2701 caagactaag gaattggctg ctaagatcat tccggttgtt gaagctaaca aggataaatg
     2761 taaccactgc aaacaaatcg ctgaactgca acaatatctt gtaaaacgca gccagtggat
     2821 cattggtggt gacggtgctt cttacgatat cggttacggt ggtcttgacc atgtaatcgc
     2881 ttccggtaag gacgttaaca tcctcgttct ggatactgaa gtttactcta acacaggtgg
     2941 tcagtcttct aaagctactc cggtaggtgc tatcgctaag ttcgctgctg ctggtaagcg
     3001 cgtacgtaag aaagacctcg gtctgatggc tactacttac ggttatgtat atgttgcaca
     3061 gatcgctatg ggtgctgacc aagctcaaac tctgaaagct atccgtgaag ctgaagcata
     3121 tcctggacca tctttgatta tcgcttacgc tccatgtatc aaccacggtc tgaaagcagg
     3181 tatgggtaag agccaggaag aagaagaaaa agctgttaag tgcggttact ggcacttgtg
     3241 gcgttacaac ccagctttgg aagaagaagg caagaaccca ttccaattgg atagcaaaga
     3301 accgaactgg gaagatttcc aaggtttctt gaagggtgaa gttcgttacg cttctgtaat
     3361 gaaacaatat cctgctgaag ctgaagaact gttcaaagct gctgaagaaa acgctaaatg
     3421 gcgttacaac agctacaaac gtttggctag agaaaactgg ggtgctgaat aatagtaata
     3481 ccctataaat ataaagcggt aatcttgtag aagattaccg cttttttatt gtatgaaccc
     3541 tgtctaacat aaacaatact ccctttttcc cactagagtt catatctatt ttatatttaa
     3601 aattaagaat aacaatgctc caatctattt attctctgac ttcggaatcc aactatccac
     3661 caactgccga tgttcatccc tccatttgcg ggctatttct tcttcatcca tccgggcatc
     3721 cttcatagct gtcataaaag agctaagttc ttctgtcgtt agtttgatgt taccaaagaa
     3781 ttcggcagca aacggatctt tctcactgaa tcctttccat gcaatagcat gtatttcttc
     3841 caagtctcca tatactttct tcggatcatc caagaatttc aagtcaaact ggtcgaacat
     3901 ccaatgcggt gtccaccccg tgatgacaat ccattctcct ttgtccatcg cttttttcaa
     3961 agaagccagc atggtggaac tacttgaagt catgagggta tacccatcaa gtccgtaagc
     4021 agcaatggcc ttatcggtcg tcttcattat ccctgctccc gcatcaattc ctactatttc
     4081 agaagagaaa cggtctttat tagcttccag ctcactaata gactggatcg taacatattg
     4141 aggaacaacc agtccgacgc gagcttctcc gtatacctcc cccaaaaatt cgatgctgtc
     4201 cccatactga tccatataat ctttcatcgt tattggtaac caggcatcca gaaacacatc
     4261 agatttcttt cctgacatag atacaaagat gggggcaagg tcagcatttt gcagttcaac
     4321 ctcatatcca tgctcttcca ataccacctt ggccaaatga ctcatggcaa taccttccag
     4381 ccaattggca taggctattt ttattttctt ttcctctagg tctgaatgag cacaggaagc
     4441 cagcaaaagc atagccgaaa gcactattcc tactatttta tatattctca tacgtatttt
     4501 atcctttccg tttagttctt attttttcgt cctgccattc cttgtgtgat acggtctaag
     4561 ataatagcta aaataacaac tactatacca ccttcaaacc caagtccgat tttcatttgg
     4621 gtaatacctt tcaatacaat ttctcccaga ccaccggcag caatcatggc agcaatgaca
     4681 accatagaaa gcgacatcat tattgtctgg ttgacaccag tcaggatagt gggcaacgcc
     4741 aaaggaagct gcactttata caataactgc caacgggtag ctccgaacga acgggaagct
     4801 tccactacat ttttaggaac ttgccggatt cccaatccgg taaggcggac cacaggaggc
     4861 atagcaaaga taatggtggc aaacactccc ggcactgctc ccaatccgaa aaacaaaacg
     4921 gcaggaatca gataaacaaa agcaggcatc gtctgcatca agtcgagaac aggacggagt
     4981 attttctctg cacgcggact gtttgccgtc cacactccta aaggtacacc aacaatcaga
     5041 gccagacagg tagatgaaaa aacgagagcc agagtttgca tggtagcctc ccaaaatccc
     5101 attccataaa tcagtaataa tcccaatgcg gtgaaaattg ccgtaccacg tcctgccttc
     5161 atccatgcga gtgcagcaag cactagaatg gttatataaa aaggtattcc aaaaagtacg
     5221 tgttggaatc ctataataaa actaccgatg cctgcattta tggcatcaaa gaaagtggaa
     5281 aaatgtacca tcatccaatt gatggccatc tctatatatt gtcctatatt tatcataaat
     5341 ctattgcgtt ttgaattatt tcgtttattt cttctttatc tttccccgtc acttcgatga
     5401 ttaaggagga aagcgggatt gttcctaaaa actcatgcgt ctcatcaatc acccataccg
     5461 gcgaattgct ctttgtcatt aaaggaagta tatcctccaa cactgtatcc tccaatacag
     5521 aatgtacttc tgtacgcaca atcgtttcaa tggatttttc ctgtctgcta cgtaacttaa
     5581 gcaggtcgtt cagacgtact tctccgacca gtttatcatc ggcgtctatg acaggtaata
     5641 cggtgatatt cttcgcacgc atcttacgaa tcaatacttc aggtccctct ttcttcaaac
     5701 gggccaccag tggtttgtca atcattaaag aagaagcggt gataatttta ctcctgtcca
     5761 cgttttcaac aaaacgggct acataatcgt tagccggttc ggtcagtatt tcttctgaag
     5821 tacctacctg caccacctct ccgtctttca taatagcaat acggtcgccc agtttaatcg
     5881 cttcactcaa gtcatgggta ataaagacaa ttgttttttt catcttcgat tgcaaagcca
     5941 gcagttcatc ctgcatttgc acacgaatca gaggatcgag cgcagagaaa gcctcatcca
     6001 ttagaagtac ttcaggatta ttagccaggg cgcgggccaa tccgacacgc tgttgcattc
     6061 caccggaaag ctcgcctacc atctgatttt catatccttt caatccgaca agcttcatac
     6121 tttccatcgc tttcttctca cgttcctctt tcttcactcc ctgaagttcg agaccgaacg
     6181 cgatattgct caatacggaa cggtgaggca acagaccgaa attctggaaa accatcgcca
     6241 actctttccg gcgaacttgc aataactctt tttcggatat tttagatata tctactccgt
     6301 ttacaagcac ttgtccggca gtaggacgta tcagacgatt gatacaacgc agtaatgtcg
     6361 attttccact tcccgagagt cccattatca cgaaaaactc tccttcatta attgaaagat
     6421 tggcatcttt cactcctacc gtacaaccgg tatctttcag aatttcctct ttactcttat
     6481 cttttttcaa catcttgagg gctttctgct tctcgttacc aaagataagg tacaaatcct
     6541 ttatttctat tttactcata taatatattg gtttagatta taatatttgt tttgttttca
     6601 actgccgcat tccttattct cacttacgat aaacaagttg aatgttcgca tggttcagtc
     6661 atgtcacatg ataacatgac ggtccgacgt tttttaaatg gtttaaaaaa aacagacaga
     6721 gtagtttaaa aggaatagaa tttgataaga ttatcctctt aatgaacagt agaaaatagt
     6781 attttcataa ataaataaca gtctgttctt gcatattgtt ggcacaaagg taaggaaaat
     6841 agattaaata tgcaaatttc attcaggtac ggagtaattc caaagatgct ttttcaagtc
     6901 tacgcatcca ttttgcttga aagagatccc ttcttccaac aagagttgtt tctgctctgt
     6961 ccaacccgga acaaggcgtc ccgatgcatt gacaacccgg tgacaaggcg tagataaatc
     7021 atccggaacc tgtttcaagg cacgccccac catacgggaa cattgaggca ttcccaataa
     7081 tgcggcaatt cccccatagg tagaaacttt acctaccgga atttcccgaa caacctgata
     7141 cacctcttga caaaaggatg cggagagact cgctttgtct actttataat ctttcatcac
     7201 tcaaacatta ctttatttca gttccaaaac tagataaaaa ggaaagaatt tgcaaataat
     7261 aaaagtattt caaataaaat atgcaacttt atttgcttta tttacaaata atcccgacct
     7321 ttgtacccat taaaagcaac cctattatta acaaaacaag cactgctgtt atgaaaaaga
     7381 agacaattct attcgcttct tgtttatttg gagtattcgc tttcagctcc tgtgagaaga
     7441 acctttatga tgaaagtaaa caacccgaga aagaaattca agtaaaagac ttggatatac
     7501 ccgcaggctt tcaatggaaa ttaactcaag tagccgcagg aacagtagct gctactaccc
     7561 ccactatggt ttccttcttt ttggatgaag catgtagtaa agaagagaaa atagccgaca
     7621 ttcctgtaga tacagaaatt tcaagtctcc ctttgagcat cccaacctac gtaaatacat
     7681 tgtatgccca gtacaaaacc agcaccaatg aaatcaaaaa agtagccata cctgtaaatg
     7741 cagatagaag tttctcactg aacattgcta atgatgccaa atccaaatct aacaccaccc
     7801 ggtcaatcac tcgtgggcat gatatagaag atgacatcca attgtcaaaa ggagtcattt
     7861 ttcatcccaa agatggttgg ggaacaatca tgtttgaaga ccaattccca tcattaggag
     7921 attatgactt taatgatttt gtagtcaatt ataaggtgca gttccaaggt attaaaaagg
     7981 ttgacaaaaa atacactgcg cagtatatac aaataggatt acgtctaaaa gctatcggag
     8041 gaatattccc ttattctcct tatttaagac tgaaagaaat agattctgac gaagtggaaa
     8101 gtatagaagt ttatgaaact aaaaacgtga ttcctgcgat cgacggagta gatcttgtcc
     8161 ccaataaaca tcttatcatt gattacagcc ctttaattaa gaatctggct aaacctgcag
     8221 gcagccaata ttataataca gaaaagaatg ctttggtagc aacaagtgat ttaccggaga
     8281 tcaatattct gatcacccta aagaagagaa aagaagtaaa ggaaatatta gaaggcgatg
     8341 aattcgactt gtatttaaaa cgtaatgata gcggaacaga aatccatatg aatggtattg
     8401 aaccgatcac ttaccaatat ccattcaatg ataaaaatct gctaccggta tatacaaacg
     8461 gggacgaaga agatgataat tattatttta gtgcaggacg cctgatttgg ggattaagag
     8521 taccaggcaa cgcagcgcat gctattgaaa aagctaattt cttggaagcc tataaaggat
     8581 tcgcaaaatg ggcgcaaagt agtggcaaaa acgaacaaaa ctggtataat caaggaaacg
     8641 cagataaaag tttattgatt cataactaac acatatcaat aaatcccggt aaacattgaa
     8701 aattcaagtt accgggattt attgtattct gacgtgaata gttttgattc tatcctttcc
     8761 ttttcagcaa atctgtcgga ctttcgccaa actgctctct ataacatttg gtaaaataag
     8821 aaggagaact aaaaccgact tcataaccaa tctccgccac tgtcatatct gacgaagcaa
     8881 gcagggaagc agccttcttc aagcgagcga tgcgaagcaa ttcattcgga gaataattag
     8941 tcagggattt tattttgcga tagagctgca cacgacttaa tcccatatcc ttacccaaat
     9001 cttctacatt caaatttgag tctcccatct ttgcttcaat caaagccttg aatttttcca
     9061 caaagtcttt atccatgtca caaacatcct ctttcgccaa cgtttgtccg tcaccaaaga
     9121 actgtttcag gcggcgatgt gaatctatca gattacgaac gcgtgccaac agcaattgcg
     9181 aactgaaggg cttggagata taagaatccg tacctccgtc atatccctga atccgttgtt
     9241 catccaaaga acaggctgtc aataagatga cagggatatg gcaggtttgc agttcgcttt
     9301 tcagccgacg acaacactct attccatcaa taccgggcat catcacatca gagattatca
     9361 agtctgggac atatttcatt gctttgcgga tgccctccga accgtctgct gcttcaatta
     9421 cagtataatc ggtatggagt aatccgcgta catacgaacg gatatctgca ttatcatcaa
     9481 ttaccaaaac agaaggtttg gaagaatcat agcctttttc cagttcctct tcttcgacaa
     9541 ctaaagattc attcaggtcg gaagaggcgg gagatccggg agaagcagga tttaaaggaa
     9601 ctgcagagat tgatgacttt agagaatctt cggccagaat agtctcacaa gtctgtaccg
     9661 gtaaatcaac ggtaaagaca gtgccctgct tttcatcact ttccacagaa attgtacctt
     9721 tatgcaattc aacaaaagct ttaaccagtg caagtccgat tcccgaaccg gcatgatgca
     9781 tgtctatttt ataaaaacga tcgaaaatgc tccggatatg ttcggcggaa atcattgaac
     9841 cggtattggc tatagtaaaa cgaatccagc gagtatcctc tttcgtcaag gaagataaac
     9901 gaactgttat ctttccattt tccggtgtga acttgaacgc attggaaagc agattaaaat
     9961 aaatacgttc caacttttcc atatccgcca atgtatggta atccgtatcc ggcatattat
    10021 caaaagagaa atgaatgtgt ttcttccggg caactgcaag gaatgattcg ttccagccct
    10081 caaaagagga aagaacatct acctgaacag gtgtatattc catcttaccg ttctcgtatt
    10141 tacggaaatc cagaatctga ttgacaagac gtaagaggat attcacgttt cgttgaatca
    10201 gcatcaacat tcgatgctga tctccactta gtgtatgatc ggccaataaa tgttctaccg
    10261 gatcagcaac caatgtaagc ggagtacgga aatcgtgaga tatatttgtg aagaaaacca
    10321 gtttggcatg cgttgcctct tccagttgat gagaaagctg gatgagctga tcccgttgtt
    10381 cttccagttt gtcccgctgt tcttccaact gtttcttctg ctcggaaagt tccttattca
    10441 gacgattttt agcacggaga gatttataga ctaccaataa taaacctgcc accaatagaa
    10501 gaataaccaa accgccatac atcaccacct gctgcgtagc aacccgagac agatatccgc
    10561 cgatacgtcc gttcaatgtt tcaatcttct gatccagttc cgagatgtga gttgtctgaa
    10621 gttgcatgac atgcgcattc gtacggtcga ccaccgcagt gttcatgacc gtttcccggg
    10681 gataaggctt tttctcaaga atattcattg ccagttgcat cactttgtcg ccattggtcg
    10741 gataaataaa agtagcattc aacacactgt cgagcaccat ttccaatccg ttacctttgc
    10801 cggggagagc atcgataccg acaaaaatca tttccttctc ccgtcccact ttctttgcag
    10861 cctgataagc tcccggagcg atacggtcgt tatgtgcata caccgcatca atcttcggat
    10921 gacggcgaag catactatcc atttccactt ccgccggttc acgttcccac gcagcatccg
    10981 ctttatcaat cagtttgata tccggaaagt tactgatagc agccataaat ccttgatggc
    11041 gttccatggc aggagttgag ccacccagtc cggtaagttc caccacattc ccttttcctt
    11101 tcaggcttga cgcaatataa ttacctaccg cacgtcctat ttcataattg tcggcaccga
    11161 tataggcagt atatttatca gaaagaatct tccggtctac caggatgaca ggtattccct
    11221 tttgataggc ttcctctaca atcggagtca tgggggccgc ttcgttggca gagataatca
    11281 ataaatcaac cccttcatct ataaaataat gaacgtcttc cgcctgttta cgattatcat
    11341 ccgcagccga ccggatttca accgatactc catcataaaa cattgcttcg cggagaattt
    11401 catcattcat cttatgccgc caggagtcat cactacattg cgccaccccg atacggaaac
    11461 gcggtgcatc ctgccgacaa gccgtcatgc caagaagaca gagcaagact gctatccact
    11521 ttgtatatcc catcattcta atcattctca tttttttcgt atttctttct atgacccaaa
    11581 tggacgattg agaacaaaaa taagaaataa aactgtgagt atgctatcta tcacccaatt
    11641 attctcatca ttaccctcca aagaaatgca aaacagttcc caatattcaa ccggaaacta
    11701 ttaacaaaag tataaagcgt aagacaaaca ctcaataaat gttataaaac atctcttttt
    11761 atttggatta tttgcagatt tagcagaagt ccgtatcttt gcaatgtgtt tttcatagta
    11821 ttagatttaa ggttaacaaa ggttggagca aggcgttgct ccttttttta tgtctatacc
    11881 tctcatatca tacgaatcat gcaaaaagaa caagaggtat attcccacag actgagatat
    11941 acctctatac ttactttcca tcaaacaatt acattagttt gtctttcaaa acctgcggaa
    12001 gttcgggcat tgcaccgctt tgcgtgcaga cataagcaga aacttcaacg gcaagtttat
    12061 gagcttcagg aaccggtttt ccattgagaa tagaagcaca gaaagcagcg gtaaaagaat
    12121 cacctgctcc caccgtatcg gcaaccggaa ctctcggcgt ctcttggaaa gagacaacac
    12181 ccggagtaaa cacataacta ccattaattc cgcaagtcag aatcagcatc ttcaggttgt
    12241 attttgccaa cagaatccaa catttatcct gtaagtcgat gccgggatag ccaaacatac
    12301 ggctgatggt caccagttct tcgtcgttta tcttcagaat gttgcaacgg cggaaagatt
    12361 cgcgcaatac ctctttggtg tagaagtcct ggcggagatt aatatcaaag attttcagtt
    12421 gtccgtctat gtcgggcatc gtatccagaa aacggttgat agtggcacgg ctcacttcat
    12481 tacgttgagc cagggaaccg aagcaaacgg cgcgcgtact caatgccaaa cgtttcagtt
    12541 catccgtaaa aggtatgtta tcccatgcca cgccttcttt gatttcgtaa caaggcactc
    12601 cctcgttatc cagtgtcact tgtaccgtac cggtaggata atccacttgt tcaatctgcg
    12661 ttttcagttt cttctcgttg aatacgttca gaatctcatc tcccaactca tccttgccca
    12721 cggcactcac cacgcgactg tcaaaaccaa actgtgatac atgataggca aagtttgccg
    12781 gagcaccacc tattttcttt ccttcgggca acacatccca aagtgcctcg cccattccta
    12841 cgattatatt attcatgatc tacggatttt attgtttcca aagttataaa attatttttt
    12901 aatacggaac gtatagaaca agagataaag cacgcccact gtcattacgg ctactgcccc
    12961 actctgtccc atggcatcgg atgctactcc catagccaac ggaaataccg tgccgccgaa
    13021 cagtcccata atcatcagac cggaaacttc atttttctta cccggcagat aaagcaatgc
    13081 ctgcgagaag actacggaga acacattgga attgccgaaa ccaatcagac cgatgcatac
    13141 ataaatcatt gtcttgtcat ggaatataaa caagcctgcc atcgctatca gcatcatcac
    13201 aacgctaatg ccgaagaaag acttcggtga catcttacgt aaaatgaaag aaccgaggaa
    13261 gcagcctgcc gtacggaaga tgaaataaag gcttgttgca aaagccgcat catcaaggcc
    13321 catgccgaga cgttccatca aaatcttggg ggcagtggta tttgttccca catcaattcc
    13381 aacgtgacac atgatgccga tgaaagaaag caggataaac ggtttgccaa gcaaagcgag
    13441 acattgtccg aaagtagacg gtttgccttc tt
//
