LOCUS       gnlProkkaFPKEEMHG_139  12521 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FPKEEMHG_139.
ACCESSION   gnlProkkaFPKEEMHG_139
VERSION     gnlProkkaFPKEEMHG_139
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 07:02:58
            Original ID  :: gnl|Prokka|FPKEEMHG_139
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 1874
            Orig. end    :: 14395
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12521
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10351]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10351
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12521
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12521
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(335..1000)
                     /locus_tag="ctg139_3"
                     /transl_table=11
                     /translation="MFEIKVSKEIKDACPVFAGAAVYAAVKNTAYSEGLWQEIDAFTGQ
                     LTSTTQMEDIKHQPVIFATREAYKRCGKDPGRYRPSAEALRRRLMRGIPLYQIDTLVDL
                     INLVSLRTGHSIGGFDADKIQGTHLELGIGKAGEPFEGIGRGVLNIEGLPVYRDSFGGI
                     GTPTSDHERTKMDLGTTHILAIVNGYNGKEGLREAAEMIQTLLRNYTESDGGKIVFFE"
     CDS             complement(1051..1863)
                     /locus_tag="ctg139_4"
                     /transl_table=11
                     /translation="MISLTKHNELKGYKSLEAYPEVAHFVTTRHEGISTGAYGSFNCSP
                     YTNDSCMNVNRNQSWLFQCMNHQIKELFIPEQNHGCASLIINESFFKESLEMRRLLLRG
                     MDALITNVPGYCVCVTTADCVPVLLYDKKQHVVAAVHAGWKGTVKHIVSNVMDHLNKMF
                     GTQGEDVIACIGPSISLESFEVGDEVYDAFEESGFDMSLISMKKKETGKYHIDLWEANR
                     IELLNLGVPAEQIEVAGICTYIHHDEFFSARRLGIDSGRTLSGIMIRK"
     CDS             complement(1860..3023)
                     /locus_tag="ctg139_5"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKGRSFGKDGADKIIEVPCGTVVYNAET
                     GEYLCDVTEDGQEVVLLKGGRGGQGNWHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSSISAAKPKIADYPFTTLEPNLGIVSYHGGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     VTKSDMLDQELMDEIEPTLPEGIPHVFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEDIVYEYEEDVDDDDDIDYEYEEEDWEEK"
     CDS             complement(3113..3682)
                     /locus_tag="ctg139_6"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMVDLDVPEEELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTAPLIDWYKNE
                     KKYQHINGLGTMEGIFAEICEAVDKL"
     CDS             complement(3742..4278)
                     /locus_tag="ctg139_7"
                     /transl_table=11
                     /translation="MDTIQIKDKLFTVSIKEQEIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGITSTGVIKEVIGLNEDIAGRTIVIVEDI
                     VDTGLTMQRLLETLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             complement(4319..5863)
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 47.6; E-value: 1.5e-14)"
                     /gene_kind="transport"
                     /locus_tag="ctg139_8"
                     /transl_table=11
                     /translation="MSALKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASTLDNTN
                     LAHWMMYGGLGFLILGNGCFKPTVSSLVGQLYEPGDRRLDAAYTIFYMGVNVGSFAAPL
                     ICGYLGDTGDPHDFKWGFLAAGIMTLFTVVLFETQKNKYLFSPSGEPIGIIPDAKREKK
                     EDKVDHISHPKMDKRTKVRNTLVITILTIALIAFFNYAFEGDWVSIGIFTACIVFPVLI
                     LLDGSLTKIERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTNRDIFGWEMPASW
                     FQSFNPLFVVILAYIMPGVWGFLNKRKMEPASPTKQAIGLLLLSLGYLFICFGVKDAVP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEAGKVKSIFGYQIATMYDFFMVFVVMSGVASLILFLLSKKLQKMMHGVE"
     CDS             complement(6057..6281)
                     /locus_tag="ctg139_9"
                     /transl_table=11
                     /translation="MMEKTKIGLNAGKVWRILNEKGELSMFDLCRELSLTFEDVALAIG
                     WLAREDKIFLRKREGMLFASIENVEFTFG"
     CDS             6922..7062
                     /locus_tag="ctg139_10"
                     /transl_table=11
                     /translation="MINKFSSHNKREKSEESCTFVIRKLKEHRNENISKQQYQEIGRLY
                     H"
     CDS             7010..8521
                     /locus_tag="ctg139_11"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPALTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSKDGIEEMET
                     NYEMLEIEQIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCQTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
     CDS             8594..9661
                     /locus_tag="ctg139_12"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELASVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVSKKVAPAPAVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKIPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             9698..9982
                     /locus_tag="ctg139_13"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(10001..10351)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg139_14"
                     /sec_met_domain="PqqD_RRE (E-value: 3.9e-11, bitscore:
                     32.8, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.7e-17, bitscore: 53.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYELRVSAYLSQMQ
                     KDGFIKLVIPVV"
     CDS             complement(10449..11837)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg139_15"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMAIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             complement(12087..12482)
                     /locus_tag="ctg139_16"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
ORIGIN
        1 cgacatacgc accactccat caaaagcagc acgaatcgta tcttttgcac aggtcttaat
       61 gtctgttccc gaatgtcctc cacgagttcc ataggcagag attacttttc ctccgggtaa
      121 tgggaaagca tattcatggt ctttcagaga atccaaatgc agatagatat gattgctttt
      181 agcaaataac ccgggagtag ctacccgtac atcagccatt tcgcgggcag agaaggagga
      241 tttatcctgc ccgtcggcag tcagtggcaa taataaaact gtcagtaaga taagtatgtt
      301 tttcatgtct tttttcttag agcactcatt ctaattattc gaagaatacg attttgcctc
      361 catccgattc tgtatagttt cttaataagg tctgtatcat ttcagcagct tctcgcaaac
      421 cttcttttcc gttataacca ttgactatgg ctaggatatg agtggttccg agatccattt
      481 tcgtacgttc atgatcgctt gtcggggttc cgattcctcc gaaagaatcg cgatatacag
      541 gtaatccttc gatattcaat acaccgcgtc cgataccttc aaacggttct cctgctttgc
      601 cgataccgag ttcaaggtgc gtaccttgta ttttgtccgc gtcaaaacca ccgatcgaat
      661 gtcccgtacg aagagacact aaattaataa ggtctaccaa cgtatcaatc tgatataaag
      721 gaattccacg catcaggcgg cggcgtagag cttcggctga cgggcggtaa cgtccggggt
      781 ctttgccaca acgtttataa gcctcacggg tagcaaagat aacgggttga tgtttgatgt
      841 cttccatctg tgtagtagaa gtcagttgcc cggtaaaagc gtcaatttcc tgccaaagcc
      901 cttcgctgta agctgtattc ttcacggcag catacacggc ggctccggca aaaaccggac
      961 atgcgtcttt tatttcttta gatactttta tttcaaacat aacttatcat aaaccaatca
     1021 tcagcgtcct gcaataacgg acaccaatta ttactttcta atcattattc ccgacaatgt
     1081 acgaccggaa tctattccca gtctacgtgc agagaagaat tcatcatgat gaatataggt
     1141 acagattccg gccacttcta tctgttctgc aggcactccg agattcagta attcaatccg
     1201 gttggcttcc cacaaatcaa tatgatattt gcctgtttct ttcttcttca tagaaatgag
     1261 agacatatcg aagccgcttt cttcaaaagc atcatacacc tcatcaccta cttcaaatga
     1321 ttcgagcgaa atgctcggcc cgatgcaagc tatcacatct tcgccttgcg tcccgaacat
     1381 cttattcaag tggtccatca cattactgac aatatgcttc accgttccct tccatccggc
     1441 atgaacggca gccacaacgt gttgtttttt gtcgtacagc aatacaggaa cacaatccgc
     1501 cgtcgtgaca caaacgcaat atcccggcac attagttatc aaggcatcca ttcctcgcag
     1561 aagtagccgt ctcatttcca atgattcttt aaaaaatgat tcattgataa tcagactggc
     1621 acagccatga ttctgttcag gaataaataa ttcctttatc tgatgattca tgcactgaaa
     1681 caaccagctc tgattgcgat tgacgttcat acatgagtcg ttggtataag gcgaacagtt
     1741 gaaagagccg taagctccgg tgcttatacc ttcgtgacgc gtagttacaa aatgagctac
     1801 ttcgggatat gcctccagtg acttatatcc cttcaactcg ttatgttttg taagtgaaat
     1861 catttttctt cccaatcttc ttcttcgtat tcataatcga tatcatcgtc atcgtcgaca
     1921 tcttcctcat attcataaac gatgtcttca tcttcgccca tgtctttgag ttcctgttgc
     1981 agacgggtca cgtctttcgg acggtgaacg atgtcctcta tcttattgct ttccttgttc
     2041 agttcttccc aaaggatgtc tttcaacacc gagatgccca aaccggaaac agaagatatg
     2101 aatacatgtg gaatgccttc cggcaatgta ggttcaatct cgtccatcaa ctcctgatcg
     2161 agcatatcac ttttggtgac agccaacaca cgttgcttgt ccaacatttc aggattgaag
     2221 gtacgcagtt cgttcagcaa aacttcgtat tctttacgaa tgtcgtcgct gtctgccgga
     2281 accataaaca gcagtaatga attacgctcg atatgacgca agaaacgcag tcccaaacct
     2341 tttccctgac tggctccttc gataataccc ggtatgtccg ccatcacaaa ggattttcca
     2401 ccgtgatagg aaacgatgcc caagttgggt tcgagcgtag taaacgggta atcggcaatt
     2461 ttcggtttgg cagccgaaat ggaagaaagc aaagttgact ttcccgcatt cgggaaacct
     2521 accagaccga catcggcaag cagtttcagc tccatgataa cggtcatttc ctgcatcggc
     2581 tctcccggct gcgcaaaacg cggagcctga cgggtggccg tcttgaaatg ccagttaccc
     2641 tgaccgccgc gaccgccttt gagcaagacc acttcctgtc cgtcttctgt tacgtcacaa
     2701 agatactccc ctgtctcggc attataaact accgttccgc agggtacttc tattatttta
     2761 tccgcaccgt cttttccgaa actacgtcct ttgctccccg attcaccatg accggccatt
     2821 gcatgacggt catacttcaa gtgcagcaat gtccagtaat tacggttacc gcgcaagatg
     2881 atatgacctc ctcttccacc atcgccccca tcaggacctc cgttaggaca atatttctcg
     2941 cgcctcatgt gcgtagagcc tcttccgccc ttacccgagc gacagtatat ctttacgtaa
     3001 tcaacaaaat tcgattcagc catatttttt taaagagtta aagtagtcag tagttagagc
     3061 agttaattag aacactccgg ctactgactt atttatttat aatattgtat tattacaatt
     3121 tatctactgc ttcgcagatt tcagcgaaga taccttccat agtacccaag ccgttgatgt
     3181 gttggtattt cttttcgttc ttgtaccagt cgatcagtgg agcagtctgt gaatgatata
     3241 catgcagacg tttcttgatt gtctcttcgt tatcatcagc acgaccggaa tccttgccac
     3301 gtttaatgag acgtaccatc agttcttctt ccggaacatc caggtcaacc ataacagaaa
     3361 cgtcctgtcc tctttctgcc aacattttct ttaatgcttc tgcctgtgca attgttcttg
     3421 ggaaaccgtc gaaaattacc cctttactat ctttgaagct gtcgaatacg cttgccagaa
     3481 tatcaatcat taattcatca ggaatcaatt gaccttggtc gatgtaacct ttagctgttt
     3541 tacccagttc tgtgccattc ttgatttcag cacgcaatac atctcctgtc gagatgtgat
     3601 tgattccata cttttctacg atacgttcgc tctgtgttcc ttttcctgaa cccggagcac
     3661 cgaaaattac gatgttcaac attttgttat ttacaattta acgatttact atttaccatt
     3721 taaactggta cctatttaat attaatctac tactgtataa atatcgggat aattacgtcc
     3781 gaaaccatca taatccagtc cgtaacctac gataaagtcg ttcgggattt ccatcgctac
     3841 atattcaatg ttgaggttta ccttgagctt ttcaggtttc accaacagag aagcgatatg
     3901 aatagcttcg ggattgcgtg tacctaatgt ttcgagcagt cgctgcatcg tcagtcctgt
     3961 gtctacgata tcttctacga tcacaatggt acgtccggca atgtcttcat tcaggccgat
     4021 tacctcttta atcactccgg tggaagtgat gccctgataa gacgccaact tcacaaatga
     4081 gatttcacaa gggatggtga tgtgcttcag taaatcagcg gtaaacatga acgaaccgtt
     4141 caacacacta aggaaaagcg gattcttacc tgccaaatcg cggttaattt cgttcgctac
     4201 gcgaatcact tctttctgaa tttcttgttc cttaatagaa acggtaaaca atttgtcttt
     4261 tatctgaatg gtatccataa ccggtaattt aaaaataacc ttgcaaaaat acgatttttt
     4321 attctacccc gtgcatcatc ttctgtaatt tcttcgagag aaggaacaga atcaacgaag
     4381 caacaccgga cattacgacg aataccataa agaaatcata catggtagca atctgataac
     4441 caaagattga cttcactttt ccggcttccg gatagagtcc gctcaacatt cccgcaaatt
     4501 tattggctgt ggcagtagac agataccaga ttcccatcat cagggaggcg aaacgtagcg
     4561 gactcaattt atttaccatt gaaagtccga taggcgacaa agctatttca cccatggtat
     4621 gaataaagta aagtcctgtc agccaaatca tgctcacttt cactccggga acagcatctt
     4681 tcactccgaa acagatgaaa agataaccta aagaaaggag taacagacca atcgcttgtt
     4741 tggtaggaga agcaggttcc atctttcgct tgttcaggaa accccataca cccggcatga
     4801 tatatgccag gataactaca aacaggggat tgaaggattg aaaccatgaa gccggcattt
     4861 cccaaccgaa tatgtcacga ttcgtctgtt cggacgcaaa aagagttaaa gaagctcccg
     4921 cctgttcgta ggctgcccag aagaagatga caaagaaggc tactatatag ataacgaaaa
     4981 tacggctgcg ttctattttg gtcaatgaac cgtctaacag gatcagaaca gggaaaacaa
     5041 tgcaggcggt aaaaatgcca atactcaccc aatcgccttc aaatgcatag ttaaagaagg
     5101 ctattaaagc aatggtaaga attgtgatta caagggtatt acgtactttg gtacgtttgt
     5161 ccatctttgg gtgtgagata tggtcgacct tgtcttcttt cttttcacgt ttagcatcgg
     5221 ggataatacc aatcggttct ccggaaggag aaaaaagata tttattcttt tgagtctcga
     5281 aaagaacaac ggtgaacagt gtcataattc cggctgcaag aaatccccat ttaaagtcat
     5341 gcggatcacc ggtatcaccc agataaccac aaatcaaagg agcagcaaaa gagcctacat
     5401 tcactcccat ataaaaaatg gtgtatgcag catccagccg cctgtctccg ggttcgtaga
     5461 gctgacctac cagagaagag acagtgggtt tgaagcaacc attgcccaga atcaggaagc
     5521 ctagtccgcc atacatcatc cagtgggcaa ggtttgtatt atctaaagtg gaggcactca
     5581 taaacatcag gaattgtccg actgccatca tcaccgctcc ccaaaacacg gaacgacgga
     5641 ttccccaata tttatcggca atgtatccgc caatcaacgg ggttaaataa actagtccgg
     5701 tatagctgcc gtagatggat gctgccgctt ctttgtcaaa caataatgcc tgcgtcagga
     5761 aaagaataaa gatcgcacgc ataccgtaat aactgaaacg ttctgccgtg cttgtcgcga
     5821 aaatcagata aaggcctttc ggatgccctt tcaatgcact catgaattta tgtgtttagt
     5881 agtttatggg gtgcaaaggt acagaaaaag tagattagat gcttctctta tcaaacagaa
     5941 taataggggg aatagtaaaa acgagcataa aaaatcctac tgatccactt cattactttt
     6001 ttagcagtgt aaataataaa gtggagatcc atcttaaatg taggttagct accaccttag
     6061 ccaaaagtaa attcgacatt ttcgatactg gcaaaaagca ttccttctct tttcctcaaa
     6121 aagattttgt cttctcgggc cagccaacca atagcaagag ctacgtcttc aaacgtcaaa
     6181 cttaattcac ggcacaaatc gaacattgaa agttcacctt tttcatttaa gatgcgccat
     6241 actttcccgg cattcaagcc aatttttgtc ttttccatca tgcaaacttt agaagattaa
     6301 acaatccgtt atttagattc taattcattg tgagcacagg aaattaatgt gatgcacatt
     6361 acctatctcc aaagataaca tttttatcgg aaacggcaaa taatcaaagg cttaatcagg
     6421 ggaaccgcat taaaaatttg tttaagaagg tatggagatg aaggaaaccg taaccacaca
     6481 tgaggtatat agcttaatac tgcctaatgt cggcactata cgacaatttt gaagttgagt
     6541 tattaataga caactgaagt cagctattta gtcaactgca gttgaccatg tagccgacag
     6601 tagtcatcta agtagccaac tacagttggc taatatcatg ccaactattt caatccggtc
     6661 ttcaatcata ttcgttctcc tatgtcttgc catattgaag aaacacctaa gcttttgctt
     6721 tgaccgggct tctttcttaa gggtgtgaac agtgtgaaag atgtgaagaa ttaaaaagag
     6781 aaccttaaat cacaacaaac atctgtcaca ctacaactta cgtgtccgtg aaacttgtga
     6841 aaggtacaaa atgattattt ttaataaatc aaaccaccac gagtttgatt catttccctg
     6901 cccccaacaa gtcatctcct tatgattaac aagttttctt cccacaacaa acgggaaaag
     6961 tcagaagaat catgtacatt tgtaatccga aaactaaaag aacatcgcaa tgaaaatatt
     7021 tccaagcagc agtatcaaga aattggacgc ttataccatt gagaacgaac ctattgcatc
     7081 aatcgatctg atggaacgtg cagcaaccgt attaacaaaa gccatcacag acagatggaa
     7141 tacggaaacg ccggtcacta tctttgccgg accggggaat aatggcggag acgctctcgc
     7201 cgtagcccgc atgatggctg aaaaaggata taaaatcgag gtatttctct tcaacacgaa
     7261 aggagaactt tcacccgact gccagaccaa taaagaactg gtagaaatga tggaagaagt
     7321 aaaattccac gagatcagta cccaattcgt acctcccgcc ctgacgcccg accatctggt
     7381 aatcgacgga ttattcggtt caggcctgaa caaaccgttg agcggtggat tcgctgccgt
     7441 agtgaaatac atcaattcct cccctgctat ggtagtagcc atcgacattc cttccggact
     7501 gatgggagaa gaaaatacat tcaacgtaaa agctaatatt atccgtgccg acgtaacttt
     7561 cagtctgcaa ctgccgaagc tcgcctttct tttcgcagag aacacggaat ttgtcggaga
     7621 atgggaagtg ctggatatcc aattgagcaa agacggtatt gaagagatgg aaacgaacta
     7681 cgaaatgttg gaaatagagc aaatccgttc actcatcaag ccacgcaaac agtttgccca
     7741 caagggaaac ttcggtcatg cactattgat tgccggttca aaaggaatgg caggagcctc
     7801 tgttctcgct gcccgtgcct gcctccgttc gggagtaggg ttgctgactg ttcatgcacc
     7861 aatgtgcaac aacgacatct tgcagacctc catacccgaa gcaatcgtag aaaccgacat
     7921 caacgaaacc tgttttgccg tacctaccga cacggacgac tatcaagcag tcggtatcgg
     7981 tccggggctg ggacgaaacg aggaaacgga agctgccttg ttggaacaac tggaacactg
     8041 ccagactcct gttgtagtgg atgccgacgc acttaatatc ctcgccaacc accgtcatgc
     8101 acttacccac ctaccgaagg gttccatcct caccccgcat ccgaaagaac tggaacgtct
     8161 gaccggcaaa tgccaggact cttacgaacg tctgatgaag gcctgcgaac tggcccgtgc
     8221 cgcccatgtt cacattattt taaaaggagc ctactccgcc atcatcaccc ccgaaggtaa
     8281 atgtttcttc aacccaaccg gaaatccggg aatggcaacc ggaggtagcg gtgacgtact
     8341 gaccggagta atcctggcac tacttgccca aggttaccca accgaggaag ccgcaaaaat
     8401 cggcacttac attcacggac tggcgggcga tgtcgctcaa aagaagcaag gaatgatcgg
     8461 aatgatcgca agcgatatta tcacctgtct gccgacagca tggcgacttg taagcgaata
     8521 aaagttaaga agttaccctt ttttcaataa cttcattaac tttgttttca aaaccagtta
     8581 aaaagaaccg aatatgaaaa agttgattat agcagcagga ctacttatga caacgtccgc
     8641 ctatgcacaa accgaagtac tgacaggggt tacccgagga aaagactatg gagtggttta
     8701 cagtcttccc aaaacccaaa tagaacttga aataaaagcc aacaaagtca actatactcc
     8761 cggagaattc agcaaatatg ctgatcgtta cctacgactg accaacgtct ccgccgaccc
     8821 tgaagagtac tgggaactgg ctagcgtaaa agtgaaatcc gtaggtgtgc ccaacagcga
     8881 aactacgtat ttcgtaaaat tgaaggataa gacagtagca ccgctcatgg aactgacaga
     8941 ggatggcatt gtgaaaacga tcaatgttcc ttacagcaat agcagtgtaa gcaaaaaagt
     9001 tgctcccgct cccgcagtcc tccaaaagaa agcgaatcct cgcgaattcc tgaccgaaga
     9061 gattctgatg gctagttcta ccgccaagat ggccgagctg gtggctaaag aaatctataa
     9121 catccgcgaa agcaaaaatg ccttattgcg cggacaagct gataatatgc cttcagatgg
     9181 ggcacagctt aaaattatgc tcgacaatct gaatgcacag gaagaagcca tgacgcaaat
     9241 gttctccggc acctgcaaca aagaagagag aacattcact gtccgcctta cccctgacaa
     9301 ggaattcaac aatgaagttg ccttccgctt ctcgaagaag ttaggtgtag ttgccaacaa
     9361 tgatttggca ggaactccgt tttatatcag tctgaaagac ctgaaatcgg tcaagatacc
     9421 acaagaagac ggtaagaaga agaaagattt ggatggaatc gcctacaacg tacccggaca
     9481 agctatggtt acattgaccg acggcaaaaa gaaactttac gaaggtgagc ttcctattac
     9541 ccaatttggt gtgatagaat atctggctcc ggttttgttc aacaagaatt ctaccatcaa
     9601 agtttatttt gatccgaata cgggaggatt gctcaaagtg gacagagaag aagggaaata
     9661 gaaaaacgag gaagtgaact tctaaaaaac aaagaatatg gttggtgaag gacatgcatt
     9721 cgacatgata cgccgaataa aagagggacg ggaagcttcc cgcctacgtc gtgaacgtgc
     9781 taacgataag ttgaagcatc taaaccgtgc aaacgaacct tatccactac ccaacaccac
     9841 ccccgaagaa atggaacgta tcatccacga ctcggagaaa aagaaagaga aagacagcaa
     9901 ttattttgtt tggggaacgc ttattatcat gggagtcctg atagcaattg ccgtcatact
     9961 ttgggctgta tttatcaaat aaataataat aagttcctat ttatacgact ggtatcacca
    10021 gttttataaa tccatctttc tgcatttgag aaagataagc cgatacacgc aactcgtagc
    10081 cctcttcatt ttgaaagtgg tctgcgagtt tttctataat ctcacgaaca ttgcgttttc
    10141 catctatcag ttcccataca gctgtaccgt gttcttccaa tttcacatga agttctttcg
    10201 acattccttt tggcacaagg aagcgttgca tccacggata tttaaaacgg ggaaaggaga
    10261 gcacaattgt ctccccttcc ctttctgctg taatatgttc actgcgacag ggaatgacct
    10321 ctaacaggtt gattttctct ttggcagcca tacttcttat tttttatttc agagtattca
    10381 tactgatact cttctgttta caccttgata caaaattcct ttgttacttt aggtattgaa
    10441 tttcctagtt acttttggat attcgcctct tccaaaccgt atcccttctt cttgttctct
    10501 gccttcaaca tcaaagccac aatcagagca agcacaccaa agagagcaaa aatagccatc
    10561 ggcaacgtgt aatcataagt ctgtgcaccg tctactaccg gacctttgca ataagtattc
    10621 aacacccatc cgatcaacaa aggaacaccc atcaatcccc agttctgtac ccagaaaatc
    10681 aatgcatatg cggtacccaa ctgtttttcc ggaataatct tcggaacaga cggccacata
    10741 gctgaaggca ccaacgagaa ggcaaatccc aatataatca tgatgatagt agcaaaccac
    10801 catatattca gtataggcag agcaaacatc gtatgcacaa aaataagcat cactgatccg
    10861 attatcatca atgtggctcc cttaccaata cggtcataaa gcgagccgaa caacggagtc
    10921 aggataatcg caccaatcgg caacaatccg ggaatcgttc ccgccaactt cggatctacg
    10981 ttatacttct gcaccatcaa gtcggcagca tacttgataa aggggaatac agccgagtag
    11041 aacaatacac atagtaatgc aatcagccag aatcctttat tggtaatgat atacacaata
    11101 tctttcatac ggaacggctc ttccggctcc aatccttctg catccaaaga agcatccaac
    11161 ttcttatcat agaaagtata aaggaagaaa gcaatcgtac ccacgcacaa cataatcaga
    11221 caaaacaaaa tcggagcagg aatattggta tgaaatgtgc cactctcatc cgtagatccg
    11281 aaaaagtcgg ccaaaggaac cgtgagcacc attgccagag ttgttccgat acgtgccgta
    11341 gccatttcaa gtcccatagc caatgccatt tccttaccct tgaaccattt cacgataatt
    11401 ttggaaactg tgataccggc aatttccaca cctacaccga agatagcata ccccaatgca
    11461 gccagggtta cctgtgtttt gaatccgaag agcatggcac cttccggaaa agtagtagaa
    11521 atcgcatagt atttcaatcc acaaccaaac accatcaata agcaagctcc cattccggta
    11581 aaacgaactc ccatcttatc caaaatgata ccaccgaaaa tcagcatcaa taggaataca
    11641 ttaaaccacc cgtaagcact tgtgaagaaa ccataatcaa gactgtccca tagtagttct
    11701 ttctcaagca tgggttttag aggagacatt acgtcggtga ggaaatagcc gcatagcata
    11761 gtaaatgcga ccaatgctag aacactccat cggagtacgg cggagtcatt caatttctgt
    11821 ttcaaatgtt ctgtcattgt tatatttaaa aatagtagtt aataatcttc atacgaccaa
    11881 caaaggtagt taaatctcgt ttgtttctat caaaaagaga ttgtttttac aagaaaaagt
    11941 taagtgcgga ttacactgac cacgcggaag attgaaaatc cgtgtaatct gcgtaatccg
    12001 cacttaaata tcaaagaaat gcagcatccg tctgcacctt cccattaatg gttttacccc
    12061 aaagtcttac ctgacaacgg agtgaattac tctgctgcag gagcaggagt ttcagtagcc
    12121 ggtgccggag tttctgtagc aggtgcattg gtagcaggag cttcagtttg cggcgcagcc
    12181 gtacctgcgg gtaagttata cgggttagtc tgttgttctt tctgtgcctg ttccaacact
    12241 gcgtctttag caacagcaga gcgaggaact acataagcag tagcaatgct cattaccacc
    12301 atgaagatag ctaagcccca tgttgctttt tccagaaaat ctgtagtctt gcgcacgccc
    12361 atgatggcgt tagatgaaga gaaaccagaa gcaagtccgc ctccttttga gttctgaatc
    12421 agcacgatga aacacatcaa caaggctgca ataaccatta agataacgaa taataagtac
    12481 atttttagtt attttgaatt agcgttaata atcaatttct c
//
